Bio 230 - Microbiology - Spring 2010 Learning Guide 01 http://www.bact.wisc.edu/Microtextbook/index.php?module=Book&func=displaychapter&chap_id=32&theme=Printer One does not have to "see bacteria" to know that they exist and that they are responsible for "chemical transformation" and infectious disease. What do you know that supports this statement? John Snow 1854 P P P P P P P http://clareverse.files.wordpress.com/2006/12/613px-snow-cholera-map.jpg IGNAZ SEMMELWEIS (July 1, 1818 - August 13, 1865) In 1841 (30 years before the GERM THEORY of disease was established) young doctor IGNAZ SEMMELWEIS was hired to run a maternity ward in a Vienna hospital. http://en.wikipedia.org/wiki/Ignaz_Semmelweis http://users.stlcc.edu/kkiser/resizeLeeuw.gif http://www.nndb.com/people/356/000087095/robert-hooke-1.jpg http://lane.stanford.edu/graphics/portals/history/HookeMicroscope800x1209px.jpg The Francesco Redi experiment 1668 History of Spontaneous Generation Year 1668 1745 1768 1859 1870 1877 Event Francesco Redi attacks spontaneous generation and disproves it for large organisms John Needham adds chick broth to a flask and boils it, lets it cool and waits. Microbes grow and he proposes it as an example of spontaneous generation. Lazzaro Spallanzani repeats Needham's experiment, but removes all the air from the flask. No growth occurs. Louis Pasteur's swan-neck flasks show that spontaneous generation does not occur. Thomas H. Huxley gives his "Biogenesis and Abiogenesis" lecture. The speech offered powerful support for Pasteur's claim to have experimentally disproved spontaneous generation. John Tyndall publishes his method for fractional sterilization, showing the existence of heat-resistant bacterial spores. What is this? http://web.ukonline.co.uk/b.gardner/kochwife.gif http://media.wiley.com/Lux/26/8326.nfg002.jpg http://www.bact.wisc.edu/themicrobialworld/anthrax.html Bacillus anthracis. Gram stain. 1500X. http://www.usal.es/~revistamedicinacine/Indice_2005/Revista/numero%202/esp/carpeta_padres_microb/Foto%2010%20a%20Robert%20K och%20(1406.jpg Lister, Joseph BRITISH SURGEON 1827–1912 http://www.chemistryexplained.com/images/chfa_03_img0510.jpg Martinus Willem Beijerinck (March 16, 1851 - January 1, 1931) http://en.citizendium.org/images/thumb/4/48/BacterConjugation.gif/350px-BacterConjugation.gif http://www2.bc.cc.ca.us/bio16/images/pilus.jpg http://www.nature.com/nrg/journal/v2/n8/images/nrg0801_634a_f3.gif Highlights in the History of Microbiology http://users.stlcc.edu/kkiser/History.page.html#Timeline A Brief History of Microbiology http://www.microbiologybytes.com/introduction/History.html MICROBIOLOGY 101/102 INTERNET TEXT CHAPTER I: A BRIEF HISTORY OF MICROBIOLOGY http://www.slic2.wsu.edu:82/hurlbert/micro101/pages/Chap1.html Antecedents of Escherichia coli B have been traced through publications, inferences, and personal communication to a strain from the Institut Pasteur in Paris used by d'Herelle in his studies of bacteriophages as early as 1918 (a strain not in the current collection). This strain appears to have passed from d'Herelle to Bordet in 1920, and from Bordet to at least three other laboratories by 1925. The strain that Gratia received from Bordet was apparently passed to Bronfenbrenner by 1924 and from him to Luria around 1941. Delbrück and Luria published the first paper calling this strain B in 1942. Its choice as the common host for phages T1– T7 by the phage group that developed around Delbrück, Luria, and Hershey in the 1940s led to widespread use of B along with E. coli K-12, chosen about the same time for biochemical and genetic studies by Tatum and Lederberg. Not all currently available strains related to B are descended from the B of Delbrück and Luria; at least three strains with somewhat different characteristics were derived independently by Hershey directly from the Bronfenbrenner strain , and a strain that appears to have passed from Bordet to Wollman is in the current Collection of the Institut Pasteur. The succession of manipulations and strains that led from the B of Delbrück and Luria to REL606 and BL21 (DE3) is given, established in part through evidence from their recently determined complete genome sequences. The End