Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Available online at www.ordoneardentistrylibrary.org ISSN 2249-488X Case – report INTERNATIONAL JOURNAL OF RESEARCH IN DENTISTRY RECONSTRUCTION OF A MIDFACIAL DEFECT USING AN INTRAORAL-EXTRAORAL COMBINATION PROSTHESIS EMPLOYING MAGNETS: A CLINICAL REPORT Dr. Arun Khalikar, Dr. Sattyam Wankhede , Dr. Bipin Muley, Dr. Nitesh Kumar Srivastava* Dept. of Prosthodontics. Govt. Dental College and Hospital, Nagpur Received: 2 Aug. 2015; Revised: 23 Sep. 2015; Accepted: 15 Oct. 2015; Available online: 5 Nov. 2015 ABSTRACT Radical maxillectomy frequently leads to extended defects in hard and soft tissues that result in a connection between the oral cavities and orbit. If the defect cannot be surgically reconstructed, a combination prosthesis may be necessary to remedy dysfunction in patient function, comfort, esthetics. For minor defects, enlargement of the base of the intra oral prosthesis is generally sufficient. Resections that affect more than one third of the maxilla usually require an intra oral and an extra oral prosthesis that could be assembled and retained in the patient. This clinical report describes a technique of prosthetic rehabilitation of midfacial defect with a silicone orbital prosthesis and intra oral obturator that are retained by magnets. Key words: Combination Prosthesis, Silicone Prosthesis, Magnets, obturators. INTRODUCTION Head and neck cancer treatment frequently leaves the patient with some facial deformity due to extensive muscle and bone loss which, in turn, can cause the patient to become depressed and isolated 1. Surgical facial reconstruction in suborbital, pre auricular, buccomandibular region are performed using skingrafts, local flaps, regional myo cutaneous flaps and composite flaps.2 Post‑surgical adjunct radiation therapy sometimes can compromise the successful regional myocutaneous flap and thus resulting in unaesthetic facial defect or oro cutaneous fistulas.3Post‑surgical defects could be rehabilitated or camouflaged using polymethyl methacrylate, latexes, vinyl polymers, copolymers, polyurethane elastomers, silicone elastomers and the various modes of retaining the facial prosthesis include straps, spectacle frames, extension from the denture, magnets, adhesives and implants material.4 This clinical report describes a technique of prosthetic rehabilitation of midfacial defect with a silicone orbital prosthesis and intraoral obturator that are retained by magnets. 46 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Case report A 34‑year‑old male patient was referred to the department of prosthodontics with an oro facial communication defect. His medical records suggested that he was diagnosed with carcinoma cuniculatum‑squamous cell carcinoma on the left maxillary alveolus extending to floor of orbit. The treatment involved extensive surgical excision of carcinomatous tissues . Post surgically he underwent 60 CYG of radiation therapy for a period of 4 weeks. The patient’s chief complaint was limited mouth opening and any solid or liquid food tends to flow out from the oro facial communication. His other major concern was his facial disfigurement and inability to socially present him to others. On extra oral examination, the defect is seen on left side of face extending from roof of orbit to upper border of zygomatic bone. Intra oral examination revealed he had partially edentulous upper arch(missing teeth 21,22,23,24,25,260 and partial edentulous lower arch(missing teeth 35,36,46). Hemimaxillectomy of maxillary left alveolus showing non healing defect that comminucate orbital defect. Procedure: 1-Diagnostic impression & fabrication DiagnosticCast & Surveying of castPreliminary impression of the maxillary arch along with the intraoral defect was made using irreversible hydrocolloid (Dentalgin; Prime Dental Products, Mumbai, India). The impressions was poured in type III gypsum material (Kalstone; Kalabhai Karson, Mumbai, India). (Fig.2) Surveying of the diagnostic cast was done and necessary mouth preparation steps were undertaken. (Fig.3) 2- Mouth Prepration,final impression & master cast fabricationAfter surveying proper guiding planes and occlusal rest seats were prepared in mouth. Maxillary custom impression tray was fabricated and adjusted for proper extensions,including the palatal defect. The impression compound was relieved and a physiologic definitive impression was made using a medium viscosity polyvinylsiloxane impression material (AQUASIL). Conventional prosthodontic protocols of boxing and pouring the impression with type III gypsum material was used to create a maxillary definitive cast. (Fig.4) 3-Wax pattern fabrication & fabrication of metal frameworkA wax pattern for framework was fabricated and casting was contemplated. (Fig.5) 4-Try in of metal framework & impression of defectMetal frame work was tried in patient mouth and impression of defect was made with medium fusing impression material (green stick) and light body impression material (AQUASIL). (Fig.6) 47 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 5-Altered cast fabricationAfter impression was made , an altered cast was fabricated (in dental stone) that contain both dentulous part and impression of defect.( Fig.7) 6-Hollowing of defect to form intraoral obturatorTo reduce the weight of intra oral obturator defect part was hollowed by packing , a pouch of salt was used( lost salt technique). Curing procedures were performed according to the manufacturer’s instructions. The cured bulb was then retrieved after deflasking, and the salt was removed after drilling 2 mm holes in the lid portion. Bulb was in two pieces that were attach together.5,6 (Fig.8.1,8.2,8.3,8.4,8.5,8.6) 7-Centric relation &teeth arrangementWith intra oral obturator was placed in mouth record centic relation teeth arrangement was done. (Fig.9.1,9.2.9.3) 8-Attach magnet on superior aspect of obturatorA pair of commercially available closed-field magnets (Cobalt-Samarium), 5 mm in diameter and 2 mm in thickness, was positioned with the help of autopolymerizing acrylic resin, and finishing and polishing was carried out in the conventional manner.7Fig-10) 9-Flasking & finishing of obturatorAfter performing adjustments, the bulb was checked in patient’s mouth .Then the bulb was kept on the cast, and a marking was done on the top portion of magnets with a copying pencil. The finished and polished prosthesis was then tried to seat on the cast. The marks transferred on the tissue surface of the prosthesis determined the position of the counter magnets. After attaching magnet flasking of obturator was done. (Fig.11.1,11.2,11.3) 10-Extraoral impression & Attachment of magnet on extra oral part of prosthesis – An irreversible hydrocolloid facial-moulage was made to record the facial defect along with surrounding normal extraoral structures and the extraorally exposed portion of the obturator with the second magnet placed over the obturator-magnet. (Fig.12) A definitive cast was formed from type III gypsum. (Fig.13) A single thickness baseplate wax was adapted over the extraoral defect area of the definitive cast. The wax sheet was flasked and processed in heat polymerized clear PMMA (Trevalon clear; Dentsply, York, PA, USA) using conventional technique. The inner PMMA framework was tried over the patient’s extraoral defect by placing obturator and second magnet in position. An indentation for the second magnet was formed on the tissue surface of the framework. A cellophane paper (DPI, Mumbai, India) was placed in between the obturator magnet and the second magnet to act as a separating medium. Auto-polymerizing clear PMMA was mixed and placed in the indentation of the second magnet formed inside the tissue surface and the framework was seated over the defect area.8 (Fig.14) 48 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 11- Waxup the facial moulge The position of the magnet was verified intra orally as well as extra orally .The other circular magnet measuring the same diameter was mounted on the orifice of the cylindrical part of acrylic conformer.The final portion of the facial prosthesis was sculpted with baseplate wax over the completed hollow PMMA substructure. (Fig.15) The wax sculpture was evaluated by positioning it on the patient’s face.( Fig.16) The wax sculpture of the prosthesis was invested in type IV gypsum material (Ultrarock; Kalabhai Karson, Mumbai, India) to form a mold for packing the silicone. Dewaxing was carried out in usual manner.9 (Fig.17) After dewaxing, a uniform coat of mold separator was applied on the warm mold (both master cast and plaster index) to facilitate separating the silicone from the mold. The prosthesis was packed with a silicone and colored using intrinsic stains selected according to the patient’s skin color. The silicone was heated for 2 hours at 90℃, deflasked, trimmed and cleaned. A conditioner was also applied onto the acrylic conformer to obtain a good bonding between the conformer and silicones. (Fig.18) The gypsum-mold was preserved for future re-packing in case of discoloration or damage of the overlying silicone layer. 14-Finishing of prosthesisWhen the mold temperature had cooled down the final RTV silicone base and catalyst were mixed in 10: 1 proportion and the thixotropic material, intrinsic colors were added similar to the trial silicone preparation.10 Once a uniform homogenous mix was obtained the silicone base shade was reverified against the patient’s skin tone and using a brush the RTV silicone was painted uniformly on the mold surface. This uniform brush application will help in eliminating any void formation. After the complete application, the plaster index was reoriented back onto the master cast and complete seating of the same was verified with the help of notches created on the land of the cast. The master cast and plaster index were secured with elastics and left for overnight curing of the RTV silicone.11 The completely cured RTV silicone’s facial prosthesis was retrieved from the mold the following day and subjected to finishing and polishing. Extrinsic stains were added to mimic the keratinized appearance and to achieve a darker lip tone. Instruction to patient- 49 • Insert and remove the prosthesis gently • Clean underline facial surface properly • Follow up regularly Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Post Prosthesis evaluationPost prosthesis delivery periodic recall and check-ups were scheduled at 1st month, 3rd month and 6th month to make any necessary adjustments. Patient was satisfied in terms of facial appearance, color matching, swallowing activity and prosthesis preventing escape of food and fluids from the mouth. There was no noticeable complication at the orocutaneous communication site due to the use of prosthesis; alternatively patient’s psychological morale was improved with the use of silicone prosthesis. Discussion Large orofacial defects result in serious functional (impairment of speech, mastication, and deglutition) as well as cosmetic deformity. The cosmetic deformity often has a significant psychological impact upon the patient. Acceptable cosmetic results usually can be obtained with a facial prosthesis. However, retention of a large prosthesis can be challenging. With ingenuity and an understanding of the remaining anatomic structures, intraoral and extraoral prostheses that mutually retain one another can be constructed. Various methods of auxiliary retention for facial prostheses have been described in the literature; they include eyeglasses,12 extensions from the denture that engage tissue undercuts,12,13 magnets,12,14 adhesives,12 combinations of the above,12,13-15 and osseointegrated implants.12,13,16,17 Although osseointegrated implants may provide the most reliable prosthesis retention; additional surgeries, expenses, inadequate bone, and prior radiation to the area may contraindicate this type of treatment.18,19 The prosthetic rehabilitation of a patient with a combined intraoralextraoral defect has been presented in this article. A 2-piece (intraoral obturator and facial) combination prosthesis was fabricated. Magnets provided mutual retention of the prosthesis. This was an esthetic option as there was sufficient space to utilize magnets without hindering the external appearance of the prosthesis. Several authors have reported different problems that compromise the serviceability of facial prostheses made of a combination of PMMA and silicone.4,20 These include degradation of the silicone properties, delamination of silicone from the PMMA base, reduced marginal integrity of the facial prosthesis, resulting in open margins, and poor simulation of facial expressions due to the rigidity and heavy-weight of the PMMA base.4,20 Increased bulk of the PMMA framework was always a worry for the prosthodontists. There has been increased interest in using a fiber-reinforced composite as a dental and medical biomaterial for the fabrication of a facial prosthesis framework which would be light-in-weight.3 This requires more sophisticated techniques and expensive materials than PMMA. This article describes a technique to make a light-weight PMMA substructure by making it hollow. The light-weight facial prosthesis facilitates better retention with magnets. The problems of delamination of silicone from PMMA base can be easily overcome by bonding the processed silicone to an underlying substructure with medical adhesive type A under vacuum as described by Lemon et al. 10 This technique is advantageous as there is no need to fabricate the whole prosthesis again in case of discoloration or damage of the silicone layer because the outer silicone layer can be removed and re-packed with the new silicone on the PMMA substructure if the mold is preserved.. The cast-metal framework improves retention, 50 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 stability, support and bracing of the prosthesis and thus increases the longevity of both prosthesis as well as supporting tissues. Major disadvantage of 2-piece prosthesis is that the mobility of intraoral obturator can make facial prosthesis mobile especially during functions. We did not find clinically significant vertical mobility or sinking down of the prosthesis during functional movements due to light weight of the prosthesis and good extraoral bony support of the remaining orbital roof and zygoma. Durability of surface-coatings of the longterm magnets is a major concern; hence it is advised to use the magnets with strong surface coatings. Periodic recall appointments at the interval of 6 months are advisable for assessment of the prosthesis (retention, stability and support) and the supporting tissues. Conclusion The oro facial communication can be successfully rehabilitated close to patient’s normal skin tone using RTV silicone facial prosthesis. The magnetically retained maxillofacial prosthesis provides an esthetically acceptable facial contour, functionally prevents food spill over from the oral cavity and boosts patient’s psychology to present themselves socially. References 1. De Sousa A. Psychological issues in acquired facial trauma. Indian J Plast Surg 2010;43:200‑5. 2. Jeng SF, Kuo YR, Wei FC, Su CY, Chien CY. Reconstruction of concomitant lip and cheek through‑and‑through defects with combined free flap and an advancement flap from the remaining lip. Plast Reconstr Surg 2004;113:491‑8. 3. Balakrishnan C, Narasimhan K, Gursel T, Jackson O, Schaffner A. Closure of orocutanous fistula using a pedicled expanded deltopectoral flap. Can J Plast Surg 2008;16:178‑80. 4. Kumar TP, Azhagarasan NS, Shankar KC, Rajan M. Prosthetic rehabilitation of orofacial donor site fistula following surgical reconstruction: A clinical report. J Prosthodont 2008;17:336‑9. 5. Guttal SS, Patil NP, Nadiger RK, Kulkarni R. A study on reproducing silicone shade guide for maxillofacial prostheses matching Indian skin color. Indian J Dent Res 2008;19:191‑5. 6. Javid N. The use of magnets in a maxillofacial prosthesis. J Prosthet Dent 1971;25:334‑41. 7. Nagaraj E, Shetty M, Krishna PD. Definitive magnetic nasal prosthesis for partial nasal defect. Indian J Dent Res 2011;22:597‑9. 8. Soganci G, Yalug S, Kocacikli M. An alternative approach to combine orbital prosthesis and obturator: A case report. Eur J Dent 2011;5:459‑64. 9. Morrow RM, Rudd KD, Rhoads JE. Dental laboratory procedures complete dentures. 2nd ed. St. Louis; Mosby; 1986. p. 312-38. 51 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 10. Lemon JC, Martin JW, King GE. Modified technique for preparing a polyurethane lining for facial prostheses. J Prosthet Dent 1992;67:228-9. 11. Udagama A. Urethane-lined silicone facial prostheses. J Prosthet Dent 1987;58:351-4. 12. Thomas K. Prosthetic rehabilitation. London; Quintessence Publishing; 1994. p. 93-103. 13. Beumer J III, Curtis TA, Marunick MT. Maxillofacial rehabilitation: prosthodontic and surgical considerations. St Louis; IshiyakuEuroAmerica Inc; 1996. p. 408-16. 14. Dumbrigue HB, Fyler A. Minimizing prosthesis movement in a midfacial defect: a clinical report. J Prosthet Dent 1997;78:341- 5. 15. Verdonck HW, Peters R, Vish LL. Retention and stability problems in a patient with a large combined intra- and extraoral defect: a case report. J Facial Somato Prosthet 1998;4:123-7. 16. Menneking H, Klein M, Hell B, Bier J. Prosthetic restoration of nasal defects: Indications for two different osseointegrated implant systems. J Facial Somato Prosthet 1998;4:29-33. 17. Worthington P. Branemark PI. Advanced osseointegration surgery: Applications in the maxillofacial region. Carol Stream, Ill; Quintessence; 1992. p. 307-26. 18. Arcuri MR, LaVelle WE, Fyler E, Jons R. Prosthetic complications of extraoral implants. J Prosthet Dent 1993;69:289-92. 19. Roumanas E, Nishimura R, Beumer J III, Moy P, Weinlander M, Lorant J. Craniofacial defects and osseointegrated implants: Six-year follow-up report on the success rates of craniofacial implants at UCLA. Int J Oral Maxillofac implants 1994;9:579-85. 20. Taft RM, Cameron SM, Knudson RC, Runyan DA. The effect of primers and surface characteristics on the adhesion-in-peel force of silicone elastomers bonded to resin materials. J Prosthet Dent 1996;76:515-8. ACKNOWLEDGEMENTS- I would like to thanks Dr.Arun Khalikar (HOD & GUIDE), Dr.Sattyam Wankhede & Dr.Bipin Muley for success of the case. 52 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 LIST OF FIGURES FIGURE 1: Preoperative photos fig.1.1 fig.1.2 fig.1.3 FIGURE 2: Diagnostic impression Fig.2 FIGURE 3: Surveying of cast Fig.3 53 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 FIGURE 4: Mouth Prepration,final impression & master cast fabrication 3- Fig.4 FIGURE 5: Wax pattern fabrication & fabrication of metal framework 4- Fig.5 FIGURE 6: Try in of metal framework & impression of defect Fig.6 54 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 FIGURE 7: Altered cast fabrication Ho Fig.7 FIGURE 8: Hollowing of defect to form intraoral obturator Fig.8.1 Adaptation of a layer of wax and Sealed wax lid. Fig.8.2 Flasking of waxed-up bulb. Fig.8.3 Dewaxing of waxed-up bulb. 55 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Fig.8.4 Packing with heat-cured PMMA. Fig.8.5 A pouch of packed salt Fig.8.6 Defect side view of bulb. FIGURE 9: Centric relation &teeth arrangement Fig.9.1 Fig.9.2 Fig.9.3 FIGURE 10: Attach magnet on superior aspect of obturator Fig-10 56 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 FIGURE 11: Flasking & finishing of obturator E E Fig.11.1 Fig.11.2 Fig.11.3 FIGURE 12: Extraoral impression Fig.12 . FIGURE 13: Definitive cast of extra oral prosthesis Fig.13 FIGURE 14: Magnet attached onextra oral prosthesis Fig.14 57 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 FIGURE 15: Wax pattern fabrication of facial sculpture Fig.15 FIGURE 16: Trial of wax sculpture Fig.16 FIGURE 17: Dewaxing Fig.17 58 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 Dr. Nitesh Kumar Srivastava et al . / IJRID Volume 5 Issue 5 Sep.-Oct. 2015 FIGURE 18: Packing of silicone material Fig.18 FIGURE 19: Pre operative &Post operative Fig.19 59 Dr. Nitesh Kumar Srivastava et al / IJRID Volume 5 Issue 5 Sep.-Oct. 2015