Optional Friday Courses / ACG’s 2015 Three-Day Clinical Review GI Pathophysiology Course Friday, October 16, 2015 • 6:30 am – 11:30 am • 310 Theater Course Director: Michael F. Vaezi, MD, PhD, MSc(Epi), FACG ACG Members/Fellows: ACG Resident/Trainee/Candidate Members: ACG PA / NP/Allied Health Members: All Non-Members: 6:30 am Welcome and Introduction Michael F. Vaezi, MD, PhD, MSc(Epi), FACG $200 $160 $175 $225 6:35 am Eosinophilic Esophagitis: Pathophysiology Directing Treatment Ikuo Hirano, MD, FACG Outline the etiology for eosinophilic esophagitis and discuss state of the art literature on diagnosis and treatment of this condition. Course Description Gain a better understanding of gastrointestinal course available on disease processes and their impact on clinical presentation of patients when you attend ACG’s GI Pathophysiology Course. Experts will review the underlying causes and clinical implication of commonly encountered diseases seen in practice. The outline includes discussion of pathophysiology of eosinophilic esophagitis, gastric and intestinal motility, H. pylori, gut microbiota, IBD, celiac disease, and endocrine neoplasms of the pancreas. Lecture presentations will be followed by interactive question and answer sessions. The discussions will be clinically based and will offer points on how to better help patients with difficult-to-manage disease processes. The course faculty are recognized experts in their fields and pioneers in better understanding of the disease processes in gastroenterology. The course is designed primarily for clinicians in GI/hepatology, as well as physician assistants, nurse practitioners, and other advanced practice healthcare professionals interested in the clinical application of GI pathophysiology. 7:15 am Gastric and Intestinal Motility: From Normal to Dysfunction Satish S. C. Rao, MD, PhD, FACG Review the physiology of gastric and intestinal motility and outline clinical conditions in which motility dysfunction leads to disease. 7:55 am Helicobacter pylori Involvement in Peptic Ulcer Disease, Gastric Cancer, Dyspepsia and Reflux: What the Clinician Should Know Douglas R. Morgan, MD, MPH, FACG Discuss the role of commonly encountered H. pylori in gastric pathology including peptic ulcer disease, cancer and dyspepsia and review its role in GERD. 8:35 am Dysbiosis, Obesity and NAFLD: What Every Gastroenterologist Needs to Know Zobair M. Younossi, MD, MPH, FACG Gut microbiota are involved in sustaining health and their imbalance may result in various GI disorders. Better understanding is needed for the role of enteric microbiota in obesity and liver disease such as NAFLD. Accreditation 9:15 am Break The American College of Gastroenterology is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. 9:30 am Mucosal Healing in the Era of Biologic Agents for Treating IBD David T. Rubin, MD, FACG Discuss recent developments in IBD including the role of mucosal healing in the era of biologic agents. The American College of Gastroenterology designates this live activity for a maximum of 4.75 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 10:10 am Celiac Disease: From Etiology to Therapy Joseph A. Murray, MD, FACG Assess the mechanisms and discuss the exciting new diagnostic options and treatment strategies for patients with celiac disease. Faculty Course Director – Michael F. Vaezi, MD, PhD, MSc(Epi), FACG Jamie S. Barkin, MD, MACG Ikuo Hirano, MD, FACG Douglas R. Morgan, MD, MPH, FACG Joseph A. Murray, MD, FACG Satish S. C. Rao, MD, PhD, FACG David T. Rubin, MD, FACG Zobair M. Younossi, MD, MPH, FACG 10:50 am Endocrine Neoplasms of the Pancreas: When to Suspect? How to Diagnose? Jamie S. Barkin, MD, MACG Formulate up to date information on endocrine neoplasms of the pancreas with emphasis on patient presentation and optimal diagnostic testing strategies. 11:30 am Course Adjourns 42 Optional Friday Courses / ACG’s 2015 Three-Day Clinical Review GI Pathophysiology Course Friday, October 16, 2015 • 6:30 am – 11:30 am • 310 Theater Course Director: Michael F. Vaezi, MD, PhD, MSc(Epi), FACG Faculty Listing and Disclosure Information The American College of Gastroenterology (ACG) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. ACG, as an ACCME accredited provider, ensures balance, independence, objectivity, and scientific rigor in all of its directly and jointly provided education activities. All who are in a position to control the content of an education activity (including their spouse or partner) are required to disclose to ACG all relevant financial relationships in any amount occurring in the past 12 months with any commercial interest that may create a conflict of interest related to the subject matter of an education activity. Safeguards against commercial bias have been put in place by ACG. Anyone who refuses to disclose relevant financial relationships will be disqualified. ACG ensures any conflicts of interest are resolved before the educational activity occurs and discloses all relevant financial relationships to the learners prior to the beginning of an education activity. ACG staff involved with this activity have nothing to disclose. Faculty have noted the following relationships related to their GI Pathophysiology Course presentations. Zobair M. Younossi, MD, MPH, FACG Chairman, Department of Medicine; VP for Research, Inova Health System, Falls Church, VA Dr. Younossi has indicated no relevant financial relationships. Course Director Michael F. Vaezi, MD, PhD, MSc(Epi), FACG Professor of Medicine, Vanderbilt University Medical Center, Nashville, TN Research Grant: Sandhill Scientific Investigational Use Disclosures ACG’s disclosure policy maintains that if any unapproved or off-label use of a product is to be referenced in a CME program, the faculty member is required to disclose that the product is either investigational or it is not labeled for the usage being discussed. The following faculty member(s) have indicated they may reference an off-label use in their GI Pathophysiology Course presentation(s). Faculty Jamie S. Barkin, MD, MACG Professor of Medicine, University of Miami, Miller School of Medicine, Miami, FL Dr. Barkin has indicated no relevant financial relationships. Ikuo Hirano, MD, FACG Professor of Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL Consultant: Meritage Pharmaceuticals, Receptos, Regeneron Douglas R. Morgan, MD, MPH, FACG Associate Professor of Medicine, Division of Gastroenterology, Hepatology and Nutrition, Vanderbilt University, Nashville, TN Dr. Morgan has indicated no relevant financial relationships. Joseph A. Murray, MD, FACG Professor of Medicine, Consultant, Division of Gastroenterology and Hepatology and Department of Immunology, Mayo Clinic, Rochester, MN Advisory Committee/Board Member: Alvine Pharmaceuticals, Inc. Consultant: AMAG Pharmaceuticals, BioLineRx, Entera Health, Inc., Genentech, GlaxoSmithKline, Glenmark Pharmaceuticals, Sonomaceuticals Grant/Research Support: Alba Therapeutics, Alvine Pharmaceuticals, Inc. Patent Holder: Miomics Satish S. C. Rao, MD, PhD, FACG Professor of Medicine, Georgia Regents University, Augusta, GA Advisory Committee/Board Member: American Medical Systems, Forest Laboratories, Hollister, In Control Medical, Ironwood Pharmaceuticals Grant/Research Support: Covidien, Salix Pharmaceuticals, Sun Sweet Corporation, Synergy Pharmaceuticals, Ventrus Laboratories David T. Rubin, MD, FACG Professor of Medicine, University of Chicago Medicine, Chicago, IL Consultant: Abbott/AbbVie, Amgen, EMMI, Genentech, Janssen, Pfizer, Prometheus, Santarus, Shire, Takeda, Telsar Pharmaceuticals, UCB Grant/Research Support: Abbott/AbbVie, Genentech, Janssen, Prometheus, Shire, Takeda, UCB Co-Founder (non-profit medical education company): Cornerstones Health Inc. Dr. Hirano – No medications or diet therapies are FDA approved for eosinophilic esophagitis at this time. All therapies are being used off label. 43 EDUCATIONAL PROGRAMS Peer Review Subcommittee Members To resolve identified conflicts of interest, the educational content was peer reviewed by the Course Director or a member of the ACG Educational Affairs Peer Review Subcommittee. J. David Horwhat, MD, FACG, Mark T. DeMeo, MD, FACG, Lancaster, PA Chair, Burr Ridge, IL Dr. Horwhat has indicated no Dr. DeMeo has indicated no relevant financial relationships. relevant financial relationships. Joseph C. Anderson, MD, FACG, Amy S. Oxentenko, MD, FACG, Rochester, MN Hanover, NH Dr. Oxentenko has indicated no Dr. Anderson has indicated no relevant financial relationships. relevant financial relationships. Michael A. Poles, MD, Steven L. Carpenter, MD, New York, NY Savannah, GA Dr. Poles has indicated no relevant Dr. Carpenter has indicated no financial relationships. relevant financial relationships. Francisco C. Ramirez, MD, FACG, Joseph G. Cheatham, MD, Scottsdale, AZ San Diego, CA Dr. Ramirez has indicated no Dr. Cheatham has indicated no relevant financial relationships. relevant financial relationships. Aasma Shaukat, MD, MPH, FACG, Edith Y. Ho, MD, Cleveland, OH Minneapolis, MN Dr. Ho has indicated no relevant Dr. Shaukat has indicated no financial relationships. relevant financial relationships.