C O V E R S T O R I E S Antitrust, Vol. 30, No. 1, Fall 2015. © 2015 by the American Bar Association. Reproduced with permission. All rights reserved. This information or any portion thereof may not be copied or disseminated in any form or by any means or stored in an electronic database or retrieval system without the express written consent of the American Bar Association. Prominent Market Definition Issues in Pharmaceutical Antitrust Cases B Y G E O R G E FA R A H A N D L A U R A A L E X A N D E R I N THE LAST TWO DECADES, MANY leading antitrust cases have challenged alleged efforts by brand-name drug manufacturers to raise or maintain supracompetitive prices for prescription drugs, largely through one method or another of delaying entry of generic competition into the marketplace. In such cases, one of the primary issues that has been consistently and contentiously litigated is what plaintiffs must show to establish market power or monopoly power. This is not a mere theoretical issue. Streamlining proof of market or monopoly power would simplify pleadings, obviate the need for expert testimony regarding market definition, and prevent dismissal of viable claims. Given ongoing controversies as to such questions in antitrust law generally, it is not surprising that there has been considerable confusion regarding the legal principles that govern questions of market power and monopoly power in cases involving pharmaceuticals. This article addresses primary points of disagreement and uncertainty with regard to how those legal principles apply in cases involving alleged efforts to delay entry of generic drugs into the marketplace. In concludes that, in the pharmaceutical context, formal market definition is not necessary to establish market or monopoly power and, when courts nonetheless insist on such a definition, there should be no presumption against defining single-product markets. “the very wording of Section 7 requires a prognosis of the probable future effect of the merger.” 2 In the context of a proposed merger, such prognostications are required because “direct” observation of the effects of the proposed merger is not possible. Indeed, recent commentary has recognized that the “necessary predicate” language of Brown Shoe stemmed from the fact that other tools for predicting future effects of a planned merger were limited in the 1960s.3 By contrast, in the context of damage claims from violations of Sections 1 and 2 of the Sherman Act—as well as damage claims for past violations of Section 7 of the Clayton Act—the challenged conduct, if proven, often will already have affected the marketplace. In such cases, when an actual lessening of competition caused by challenged conduct can be observed directly, the Supreme Court has held that a market need not be defined. Thus, in FTC v. Indiana Federation of Dentists, which involved alleged violations of Section 1 of the Sherman Act, the Court observed that “as a result of” the challenged conduct, dental insurers “were, over a period of years, actually unable to obtain compliance with their requests for submission of x rays.” 4 The Court reasoned: Is Market Definition Necessary? In Brown Shoe Co. v. United States, the Supreme Court famously stated that “proper definition of the market is a ‘necessary predicate’” to determining whether the effect of a merger may be substantially to lessen competition, or to tend to create a monopoly, “in any line of commerce,” in the context of a suit seeking to enjoin a proposed merger.1 It based that statement on “line of commerce” language in Section 7 of the Clayton Act, which has no counterpart in Sections 1 or 2 of the Sherman Act, coupled with an observation that The Court therefore concluded that “the finding of actual, sustained adverse effects on competition . . . is legally sufficient to support a finding that the challenged restraint was unreasonable even in the absence of elaborate market analysis.” 6 Prominent case law since then has reaffirmed that direct evidence of market power or anticompetitive effect may obviate the need for any formal market definition analysis for Section 1 rule of reason claims.7 In the context of monopolization claims under Section 2, courts have readily reached a similar conclusion in view of the classic definition of “monopoly power” under Section 2 as “the power to control prices or exclude competition.” 8 When a competitor can be shown to have acquired actual power to control prices as a consequence of the challenged conduct, multiple courts of appeals have squarely held that market def- George Farah is a partner in the New York office of Cohen Milstein Sellers & Toll PLLC. Laura Alexander is an associate in the Washington office of Cohen Milstein Sellers & Toll PLLC. 4 6 · A N T I T R U S T Since the purpose of the inquiries into market definition and market power is to determine whether an arrangement has the potential for genuine adverse effects on competition, “proof of actual detrimental effects, such as a reduction of output,” can obviate the need for an inquiry into market power, which is but a “surrogate for detrimental effects.” 5 inition is not necessary for a Section 2 claim.9 Leading commentators have largely agreed.10 In particular, at least three prominent authorities have recently raised compelling theoretical challenges to the notion that formal market definition is useful to antitrust analysis when market power can already be shown based on direct, historical evidence.11 In the specific context of antitrust litigation involving claims of delayed generic entry, principles that support dispensing with any formal market definition requirements apply even more clearly. When a generic drug comes to market, the price that can be charged for the brand-name drug invariably plummets by a substantial margin.12 When generic entry has this price effect in the marketplace, some courts have expressly recognized that the observed price effect by itself can establish market or monopoly power, without a need for formal market definition.13 Furthermore, even when no generic competitor has yet entered the market, some courts have recognized that the frequency with which generic drug entry sharply depresses brand-name drug prices may justify a factfinder in concluding that the brand-name company exercises market power prior to generic entry.14 Is Functional Substitutability Enough to Warrant Inclusion in the Same Product Market? Despite the principles outlined above and their clear support in the Supreme Court’s decision in Indiana Federation of Dentists, some lower courts have continued to treat formal market definition as though it were a necessary step in establishing market power or monopoly power in pharmaceutical antitrust cases.15 In many of these cases it is questionable whether any genuine market definition analysis is required, as distinguished from analysis of direct evidence of market power, since the basis for the market definition is often merely the observation that market power exists.16 These cases illustrate one of the principal points made by Professor Louis Kaplow in recent scholarship, that much of what passes for “market definition” analysis is really nothing more than “a purely results-oriented market definition stratagem under which one first determines the right legal answer” based on direct observations about market power “and then announces a market definition that ratifies it.” 17 In such cases, it would be more accurate to recognize that the basis of the analysis is reliance on direct evidence of market power, rather than any genuine formal market definition analysis, and that adherence to any requirement of “market definition” only tends to obscure the real issues in play. Nevertheless, when courts have required proof of the relevant market in pharmaceutical antitrust cases, fact issues frequently arise as to whether other drugs in the same therapeutic class should be included in the relevant product market with the drugs at issue in the case. The Supreme Court has defined monopoly power innumerable times as “the power to control prices or exclude competition.” The fact that two products may be substituted for one another functionally should therefore have no bearing on the presence of market power or monopoly power, absent evidence that such substitutability eliminates the power to control prices.18 By extension, two drugs in the same therapeutic class should not be considered part of the same product market if competition from the second drug fails to trigger competitive pricing for the first drug. Accordingly, many cases in the pharmaceutical context have limited the relevant antitrust market to the branded and generic versions of a single formulation of a single drug, even when other drugs within the same therapeutic class have been available.19 Courts in a few other cases have reached the opposite conclusion, in our view based on a misconception as to when mere functional substitutes should be excluded from the relevant market.20 This confusion arises in part from the ABA Model Jury Instructions, which state (erroneously, we believe) that different products should be included in the same product market whenever they are “reasonable alternatives,” without regard to whether competition from one product prevents the manufacturer of the other from raising prices above a competitive level.21 This approach to market definition is analytically inappropriate because it does not focus on the drug maker’s “power to control price,” which is the touchstone for determinations of market and monopoly power. In the specific context of antitr ust litigation involving claims of delayed generic entr y, principles that suppor t dispensing with any for mal mar ket definition requirements apply even more clear ly. “Single Brand” Markets When successful marketing permits a competitor to raise prices on its products even though others produce essentially identical products, some courts have found it inappropriate to define the successful brand by itself as a distinct product market. Accordingly, in non-pharmaceutical antitrust cases, “single brand” markets have been generally disfavored when the products being considered for inclusion in the market are essentially identical.22 It makes no sense to apply these principles, however, where differences among products do not merely involve brand names but instead are substantive differences that stem from patent or copyright protection. Thus, in Fortner Enterprises, the Supreme Court recognized that one manufacturer’s product can confer economic power “when other competitors are in some way prevented from offering the distinctive product themselves. Such barriers may be legal, as in the case of patented and copyrighted products.” 23 In most pharmaceutical antitrust cases, the branded drug maker has unexpired patents on the branded drug, along with corresponding regulatory limitations on the manufacF A L L 2 0 1 5 · 4 7 C O V E R ture and sale of competing generic drugs under the HatchWaxman Act. Thus, differences between the brand-name drug and its generic equivalents, on the one hand, and other drugs in the same therapeutic class, on the other, are not mere branding differences but instead are substantive differences stemming from ways in which the law prevents competing producers “from offering the distinctive product themselves.” Moreover, prescriptions that physicians write for a particular brand-name drug may be filled with a generic equivalent but not by a different drug in the same class. Accordingly, consistent with the Fortner decision, presumptions against “single brand markets” should not apply in pharmaceutical antitrust cases, as some courts have recognized.24 Nonetheless, some courts have applied a presumption against “single brand markets” in pharmaceutical antitrust cases even when controlling law—including patent law protection for the brand-name product—prevents rival drug makers in the same drug class from offering a product identical to the branded drug at issue in the case.25 These rulings in our view misapply the presumption against “single brand markets,” which should apply only where there is no legal hindrance to competing producers selling the same product as the brand in question. S T O R I E S Trading Co., 381 F.3d 717, 736–37 (7th Cir. 2004); Toys “R” Us, Inc. v. FTC, 221 F.3d 928, 937 (7th Cir. 2000). 8 Eastman Kodak Co. v. Image Technical Servs., Inc., 504 U.S. 451, 481 (1992) (monopoly power is the “power to control prices or exclude competition”) (citation omitted). 9 Broadcom Corp. v. Qualcomm Inc., 501 F.3d 297, 307 & n.3 (3d Cir. 2007) (stating in Section 2 case that “direct proof of monopoly power does not require a definition of the relevant market”); Heerwagen v. Clear Channel Commc’ns, 435 F.3d 219, 227 (2d Cir. 2006) (stating in Section 2 case that “[i]ndirect proof of market power, that is, proof that the defendant has a large percentage share of the relevant market, is [merely] a ‘surrogate’ for direct proof of market power” when direct evidence is not available or is ambiguous), overruled on other grounds by In re IPO Securities Litig., 471 F.3d 24, 42 (2d Cir. 2006); see also King Drug, 791 F.3d at 412; PepsiCo., Inc. v. Coca-Cola Co., 315 F.3d 101, 107 (2d Cir. 2002); Re/Max Int’l, Inc. v. RealtyOne, Inc., 173 F.3d 995, 1026 (6th Cir. 1999); Rebel Oil Co. v. Atl. Richfield Co., 51 F.3d 1421, 1434 (9th Cir. 1995); United States v. Microsoft Corp., 253 F.3d 34, 51 (D.C. Cir. 2001). 10 See A NDREW I. G AVIL , W ILLIAM E. K OVACIC & J ONATHAN B. B AKER , A NTITRUST L AW IN P ERSPECTIVE 919 (2d ed. 2008) (“[E]vidence of the actual ability . . . [to] raise prices . . . establishes market power . . . and it may do so more reliably than market share evidence.”); L AWRENCE A. S ULLIVAN & WARREN S. G RIMES , T HE L AW OF A NTITRUST 74 (2d ed. 2006) (“Disputes about market definition . . . are of little consequence in the face of actual evidence of anticompetitive effects.”); Phillip Areeda, Market Definition and Horizontal Restraints, 52 A NTITRUST L.J. 553, 565 (1983) (“[M]arket definition and market shares are second best to direct measurement.”). 11 Louis Kaplow, Why (Ever) Define Markets?, 124 H ARV. L. R EV. 437, 440 (2010) [hereinafter Kaplow, Why (Ever) Define Markets? ]; U.S. Dep’t of Justice & Fed. Trade Comm’n Horizontal Merger Guidelines § 2.1.2 (2010), http://www.ftc.gov/os/2010/08/100819hmg.pdf; Herbert Hovenkamp, Markets in Merger Analysis; Merger Policy, Structuralism, and the Legacy of Brown Shoe, 57 A NTITRUST B ULL . 887; see also J. Douglas Richards, Is Market Definition Necessary in Sherman Act Cases When Anticompetitive Effects Can Be Shown with Direct Evidence?, A NTITRUST , Summer 2012, at 53–59 (discussing these three authorities at greater length); Louis Kaplow, Market Definition: Impossible and Counterproductive, 79 A NTITRUST L.J. 361 (2013) (elaborating on prior work and subsequent response); Daniel A. Crane, Market Power Without Market Definition, 90 N OTRE D AME L. R EV. 31 (2014) (proposing framework for market power analysis in a post-market definition world). But see Gregory J. Werden, Why (Ever) Define Markets? An Answer to Professor Kaplow, 78 A NTITRUST L.J. 729 (2014); Gregory J. Werden, The Relevant Market: Possible and Productive, http://www. americanbar.org/content/dam/aba/publishing/antitrust_law_journal/at_ alj_werden.aut hcheckdam.pdf. 12 See Eric L. Cramer & Daniel Berger, The Superiority of Direct Proof of Monopoly Power and Anticompetitive Effects in Antitrust Cases Involving Delayed Entry of Generic Drugs, 39 U.S.F. L. R EV. 81, 106–08 & nn.86–94 (2004) (citing data showing that entry of generic drugs virtually always yields much lower prices, so that actions taken to delay generic entry unquestionably have anticompetitive effects in most cases). 13 See New York v. Actavis, PLC, No. 14-cv-7473, 2014 U.S. Dist. LEXIS 172918, at *101 (S.D.N.Y. Dec. 11, 2014) (“Market power may also be established by considering evidence of anticompetitive effects of the challenged conduct.”), aff’d, 787 F.3d 638 (2d Cir. 2015); Apotex, Inc. v. Cephalon, Inc., No. 2:06-cv-2768, 2014 U.S. Dist. LEXIS 131453, at *7 (E.D. Pa. Aug. 18, 2014) (“Monopoly power is ‘the power to control prices or exclude competition.’ That power may be proven through ‘direct evidence of supracompetitive prices and restricted output,’ or ‘inferred from the structure and composition of the relevant market.’”) (citations omitted); In re Nexium (Esomeprazole) Antitrust Litig., 968 F. Supp. 2d 367, 388 n.19 (D. Mass. 2013) (“Where direct evidence of market power is available, however, a plaintiff need not attempt to define the relevant market.”); In re Neurontin Antitrust Litig., MDL No. 1479, 2013 U.S. Dist. LEXIS 111587, at *16–17 (D.N.J. Aug. 8, 2013) (“Plaintiffs have proffered evidence of, inter alia, Defendants’ costs, Defendants’ lost sales after generic entry, and Defendants’ sale after generic entry of their own low-priced generic that was Conclusion In antitrust litigation involving claims of delayed generic entry, it should be, and has often been held to be, unnecessary to formally define a relevant market, as market power is evident when prices invariably plummet in response to generic entry. Some courts in pharmaceutical antitrust cases have nonetheless required the plaintiff to allege and prove a relevant market. In such circumstances, many courts have appropriately limited the relevant antitrust market to the branded and generic versions of a single formulation of a single drug, even when other drugs within the same therapeutic class have been available and regardless of the general antipathy for “single brand markets” in the non-pharmaceutical context.䡵 1 370 U.S. 294, 324, 335 (1962). 2 Id. at 332 (emphasis added). 3 Gregory J. Werden, Why (Ever) Define Markets? An Answer to Professor Kaplow, 78 A NTITRUST L.J. 729 (2014). See also Gregory J. Werden, The Relevant Market: Possible and Productive, http://www.americanbar.org/ content/dam/aba/publishing/antitrust_law_journal/at_alj_werden.auth checkdam.pdf. 4 476 U.S. 447, 460 (1986). 5 Id. at 460–61 (quoting 7 P HILLIP A REEDA , A NTITRUST L AW ¶ 1511, at 429 (1986)). 6 Id. at 461. 7 Ball Mem’l Hosp., Inc. v. Mut. Hosp. Ins., Inc., 784 F.2d 1325, 1336 (7th Cir. 1986) (stating in Section 1 rule of reason case that “Market share is just a way of estimating market power, which is the ultimate consideration. When there are better ways to estimate market power, the court should use them.”). See also King Drug Co. of Florence, Inc. v. Smithkline Beecham Corp., 791 F.3d 388, 412 (3d Cir. 2015); Republic Tobacco Co. v. N. Atl. 4 8 · A N T I T R U S T nearly identical to Neurontin.”); In re Ciprofloxacin Hydrochloride Antitrust Litig., 363 F. Supp. 2d 514, 521–23 (E.D.N.Y. 2005) (“In general, to sidestep the traditional relevant market analysis, a plaintiff must show by direct evidence ‘an actual adverse effect on competition’ . . . . [B]oth Bayer and Barr expected Bayer to lose significant sales once generic competition began, with Bayer estimating losses of between $510 million and $826 million in Cipro sales during the first two years of generic competition[.]”); Knoll Pharm. Co. v. Teva Pharm. USA, Inc., No. 01-C-1646, 2001 WL 1001117, at *3–4 (N.D. Ill. Aug. 24, 2001) (allegation that brand-name company exercised market power due to patent protection prior to generic entry sufficient to defeat motion to dismiss). 14 See Actavis, 2014 U.S. Dist. LEXIS 172918 at *101–02 (“Prior to July 2015, Defendants have 100% of the market, there is no competition, development is controlled by Defendants, Defendants’ patent [sic] are absolute barriers to entry, and demand is inelastic: Defendants have monopoly power. See generally FOF § IV. Starting in July 2015, however, several generic manufacturers enter the memantine market and Defendants’ memantine market share is projected to drop below 100%.”); Nexium, 968 F. Supp. 2d at 389 (“This Court need not engage in an extensive analysis of circumstantial evidence of market power because direct evidence of such power is available—the Direct Purchasers have thoroughly alleged that AstraZeneca, in its position as a monopolist, has been able to charge supracompetitive prices for brand Nexium.”); FTC v. Lundbeck, Inc., Nos. 08-6381 & 08-6379, 2009 U.S. Dist. LEXIS 62561 (D. Minn. July 21, 2009) (denying summary judgment on the basis that a factfinder may find defendant possessed market power prior to generic entry). 15 See, e.g., Am. Sales Co. v. AstraZeneca AB, No. 10 Civ. 6062 (PKC), 2011 WL 1465786 (S.D.N.Y. Apr. 14, 2011) (dismissing complaint premised on market limited to a single PPK, Prilosec OTC); Kaiser Found. v. Abbott Labs., No. CV 02-2443-JFW (FMOx), 2009 U.S. Dist. LEXIS 107512, at *26 (C.D. Cal. Oct. 8, 2009) (rejecting market limited to Hytrin and its generic copies because it excluded other alpha-blockers); La. Wholesale Drug Co. v. SanofiAventis, No. 07 Civ. 7343(HB), 2008 WL 169362, at *7 (S.D.N.Y. Jan 18, 2008) (product market limited to branded and generic versions of Arava was cognizable); Mut. Pharm. Co. v. Hoechst Marion Roussel, Inc., No. Civ. A. 961409, 1997 WL 805261, at *2–3 (E.D. Pa. Dec. 17, 1997); Smithkline Corp. v. Eli Lilly Corp., 575 F.2d 1056, 1064 (3d Cir. 1978). 16 See, e.g., Neurontin, 2013 U.S. Dist. LEXIS 111587, at *10–11 (“The Court concludes that Plaintiffs must define, at least with a degree of approximation, the relevant market in their analysis under the direct evidence method.”) 17 Kaplow, Why (Ever) Define Markets?, supra note 11, at 440. 18 See, e.g., Telecor Commc’ns., Inc. v. Sw. Bell Tel. Co., 305 F.3d 1124, 1132 (10th Cir. 2002) (“Reasonable interchangeability does not depend upon product similarity.”); United States v. Archer-Daniels-Midland Co., 866 F.2d 242, 248 & n.1 (8th Cir. 1988) (sugar and high fructose corn syrup, though functionally interchangeable, do not reside in the same antitrust product market); FTC v. Staples, Inc., 970 F. Supp. 1066, 1074 (D.D.C. 1997); In re Lorazepam & Clorazepate Antitrust Litig., 467 F. Supp. 2d 74, 81 (D.D.C. 2006) (“The fact that products are just functionally interchangeable does not compel a finding that they belong in the same market.”). 19 See, e.g., Actavis, 2014 U.S. Dist. LEXIS 172918, at *97 (“As in this instance, courts have found a single brand-name drug and its generic equivalents to be a relevant product market in cases where the challenged conduct involves a branded drug manufacturer’s effort to exclude generic competition.”); Nexium, 968 F. Supp. 2d at 377–88 (“The fact that other drugs may be used to treat heartburn and related conditions is immaterial to the present inquiry.”); Andrx Pharm., Inc. v. Elan Corp., 421 F.3d 1227, 1235–36 (11th Cir. 2005) (relevant market limited to controlled release naproxen); Eli Lilly, 575 F.2d at 1064 (relevant market was cephalosporins, not other anti-infectives); Wholesale Drug, 2008 WL 169362, at *7 (product market limited to branded and generic versions of Arava was cognizable); Ciprofloxacin, 363 F. Supp. 2d at 522–23 (relevant market limited to drug product ciprofloxacin, not other flouroquinolone antibiotics); In re Terazosin Hydrochloride Antitrust Litig., 352 F. Supp. 2d 1279, 1319 n.40 (S.D. Fla. 2005) (relevant market limited to branded and generic terazosin hydrochloride); Knoll Pharm., 2001 WL 1001117, at *3–4 (product market limited to hydrocodone bitartrate/ibuprofen was cognizable); In re Cardizem CD Antitrust Litig., 105 F. Supp. 2d 618, 680–81 (E.D. Mich. 2000) (approving product market limited to branded and generic versions of Cardizem CD); Hoechst, 1997 WL 805261, at *2–3 (relevant market could be limited to Seldane, and excluded Claritin, because of unique formulations). 20 See, e.g., Bayer Schering Pharma AG v. Sandoz, Inc., 813 F. Supp. 2d 569 (S.D.N.Y. 2011) (dismissing complaint premised on market limited to oral contraceptives containing drospirenone); American Sales, 2011 WL 1465786 (dismissing complaint premised on market limited to a single PPK, Prilosec OTC); Kaiser Found., 2009 U.S. Dist. LEXIS 107512, at *26 (rejecting market limited to Hytrin and its generic copies because it excluded other alpha-blockers); Asahi Glass Co. v. Pentech Pharm., Inc., 289 F. Supp. 2d 986, 996 (N.D. Ill. 2003) (Posner, J., by designation) (stating that it “cannot merely be assumed” that Paxil does not compete with other antidepressant medications). 21 See ABA M ODEL J URY I NSTRUCTIONS IN C IVIL A NTITRUST C ASES , at C-7 (“[I]f consumers seeking to cover leftover food for storage considered certain types of flexible wrapping material—such as aluminum foil, cellophane, or even plastic containers—to be reasonable alternatives, then all those products would be in the same relevant product market.”). 22 See Pioneer Family Invs., LLC v. Lorusso, No. CV 14-00594, 2014 WL 2883058, at *5 (D. Ariz. 2014) (“Generally, a relevant market in a monopolization action cannot be limited to the products of a single manufacturer.”) (citation omitted); Dang v. S.F. Forty Niners, 964 F. Supp. 2d 1097, 1105 (N.D. Cal. 2013) (“Defendants are correct that single-brand markets typically do not constitute legally cognizable markets for the purposes of an antitrust suit.”); U.S. Ring Binder L.P. v. World Wide Stationery Mfg. Co., 804 F. Supp. 2d 588, 598–99 (N.D. Ohio 2011) (rejecting market limited to single company’s ring binder products); Apple Inc. v. Psystar Corp., 586 F. Supp. 2d 1190, 1198 (N.D. Cal. 2008) (“Single-brand markets are, at a minimum, extremely rare.”); Green Country Food Mkt., Inc. v. Bottling Grp., 371 F.3d 1275, 1282 (10th Cir. 2004) (“In general, a manufacturer’s own products do not themselves comprise a relevant product market. . . . Even where brand loyalty is intense, courts reject the argument that a single branded product constitutes a relevant market.”); Hack v. President & Fellows of Yale College, 237 F.3d 81, 86–87 (2d Cir. 2000) (housing at a single university), abrogation on other grounds recognized by Diamond v. Local 807 Mgmt. Pension Fund, 595 Fed. App’x 22, 25 (2d Cir. 2014); Flash Elecs., Inc. v. Universal Music & Video Distrib. Corp., 312 F. Supp. 2d 379, 391 (E.D.N.Y 2004) (specific movies); Mathias v. Daily News, L.P., 152 F. Supp. 2d 465, 482 (S.D.N.Y. 2001) (specific newspaper); Shaw v. Rolex Watch, U.S.A., Inc., 673 F. Supp. 674, 679 (S.D.N.Y. 1987) (Rolex watches); Deep S. Pepsi-Cola Bottling Co. v. Pepsico, Inc., No. 88 CIV. 6243, 1989 WL 48400, at *8 (S.D.N.Y. May 2, 1989) (distribution of a single soft-drink brand). 23 Fortner Enters., Inc. v. U.S. Steel Corp., 394 U.S. 495, 505 n.2 (1969). 24 See URL Pharma, Inc. v. Reckitt Benckiser, Inc., No. 15-505, 2015 WL 5042911, at *6 (E.D. Pa. Aug. 25, 2015) (holding that “a single product may, in some cases, constitute a separate relevant market” and citing several pharmaceutical cases in support); Actavis, 2014 U.S. Dist. LEXIS 172918, at *97 (“As in this instance, courts have found a single brandname drug and its generic equivalents to be a relevant product market in cases where the challenged conduct involves a branded drug manufacturer’s effort to exclude generic competition.”); Cardizem, 105 F. Supp. 2d at 680 (“[A] single brand of a product can constitute a relevant market for antitrust purposes.”); Hoechst, 1997 WL 805261, at *3 (“The Supreme Court has held that in some instances a single brand of a product may constitute a relevant market or a separate submarket.”). 25 See, e.g., Bayer Schering, 813 F. Supp. 2d 569 (dismissing complaint premised on market limited to oral contraceptives containing drospirenone); American Sales, 2011 WL 1465786 (dismissing complaint premised on market limited to a single PPK, Prilosec OTC); Kaiser Found., 2009 U.S. Dist. LEXIS 107512, at *26 (rejecting market limited to Hytrin and its generic copies because it excluded other alpha-blockers); Asahi Glass, 289 F. Supp. 2d at 996 (Posner, J., by designation) (stating that it “cannot merely be assumed” that Paxil does not compete with other antidepressant medications). F A L L 2 0 1 5 · 4 9