Title: A Closer Look at Generic Prescription Drugs As all of us continue to look for ways to save money on products that we use everyday, generic prescription drugs offer cost savings that many of us often overlook. To take advantage of these savings, ask your physician about generic alternatives for any drugs you are currently taking. Generic drugs are almost always lower in cost than their brand-name drug equivalents. And when you take prescription drugs on a daily or routine basis (such as diabetes or high-blood pressure medications) your cost savings can quickly add up. What are generic drugs? A generic drug is a chemically identical version of a brand-name drug in the following ways: dosage form, safety, strength, route of administration (e.g., by mouth or inhalation), quality, effectiveness and intended use. Generic drugs are required by the Food and Drug Administration (FDA) to have the same quality, strength, purity, potency and stability as their brand-name counterparts. In short, generic drugs are required to have the same active ingredients as brand-name drugs. Generic drugs may look different from brand-name drugs due to the inactive ingredient(s) used to manufacture the generic drug. This may make the drug different in color, shape, size or even taste compared to its brand-name equivalent. These inactive ingredients do not affect the effectiveness of generic drugs. The following chart lists some commonly prescribed drugs and their generic equivalent: Brand Name Ambien® Cozaar® Valtrex® Effexor XR® Prozac® Zocor® Protonix® Wellbutrin XL® Generic name Zolpidem Losartan Valacyclovir Venlafaxine Fluoxetine Simvastatin Pantoprazole Buproprion Treatment condition Insomnia high blood pressure Herpes Depression Depression high cholesterol heartburn/GERD Depression When a pharmaceutical company receives approval for its brand-name drug by the FDA, the company is given a patent for up to 20 years. This patent allows the company to manufacture, market, price and sell their patented product exclusively during this time period. Once the patent expires on the brand-name drug, other pharmaceutical companies can manufacture and sell generic versions of the brand-name drug. Page 1 of 3 Brand-name drugs are expensive because of the high initial investment costs associated with the research, development, clinical trials, marketing, advertising and promotion required to develop and market a new product. For example, in 2009, Astra Zeneca spent $132 million to advertise Crestor®, a brand-name drug used to treat high cholesterol. Pharmaceutical companies that manufacture generic drugs can sell them at lower prices, not because the products are of lesser quality, but because they don’t have the same upfront investment costs. In the next four years, six of the 10 top-selling brand-name drugs in the U.S. will no longer be under patent. These include Plavix® (a blood thinner), and Lunesta® (a drug commonly used to treat insomnia). Greater numbers of generic drugs means greater saving opportunities. The following chart lists drugs that will be losing their patent in the next few years Estimated date of generic availability July 2012 November 2013 May 2014 July 2016 Brand Name Generic Name Treatment condition Lunesta® Aciphex® Nexium® Crestor® Eszopiclone Rabeprazole Esomeprazole Rosuvastatin Insomnia Heartburn/GERD Heartburn/GERD High cholesterol How to save by using generics? Most health plans offer generic drugs at the lowest copayment tier which will help you reduce your healthcare costs. The chart below shows how you can save money on your copayments by using generics. Formulary tier Copayment (30-day supply) Total copayment savings for a 30-day supply Total annual savings* Brand-name Drug X Tier 2-Preferred brand $40.00 $30 Generic version of Drug X Tier 1-Generic brand $10.00 $360 *Total annual savings based on 12 monthly fills You can begin saving money on generic drugs quickly and easily. The next time you have a prescription, ask your physician or pharmacist if a generic alternative is available. Conclusion: Generic drugs are just as effective as brand-name drugs. Using generic drugs, when appropriate, is one of many cost-saving solutions that can reduce your prescription drug costs. Page 2 of 3 Page 3 of 3