Molecular Biology and Microbiology (5,140 patents)
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Patent No.
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Title
Simplified in-vitro interferon production
Electrode for the electrochemical regeneration of coenzyme, a
method of making said electrode, and the use thereof
Coupled enzyme systems for determination of dissolved
substances
Method for screening microorganisms for the production of
amylolytic enzymes
Polysaccharide production using novel strains of Pseudomonas
mendocina
Production of ethanol by yeast using xylulose
Production of ethanol by fermentation
Process for the separation and purification of dextranase
Microorganisms of the genus Pseudomonas and process for
degrading compounds which contain methyl groups in aqueous
solutions
Sensitive tests for malignancies based on DNA detection
Labeled antibodies and methods
Anaerobic digestion process for organic wastes
Device for dispersing a second phase in a first phase
Assay method for lipid component, assay composition, and
process for production of enzyme used therefor
Process for producing antibodies to hepatitis virus and cell lines
therefor
Package for collecting cultures
Probe for use in a microcalorimeter
Heterogenous specific binding assay employing an enzyme
substrate as label
Method for discriminating between unstained and absorbing dye
stained cells
Method and means for assessment and prediction of risk of
subsequent ischemic cardiac events
Composition and method for the determination of hydrogen
peroxide
Process for isomerizing L-mannose to L-fructose
Microorganisms of the genus Hyphomicrobium and process for
degrading compounds wich contain methyl groups in aqueous
solutions
Process for preparing L-threonine
Hybrid vector and process for improving the amplification and
expression of hybrid vectors by the use of mitochondrial DNA
HLA D Typing assay
Complement assay method
Method for separating ethanol from an ethanol containing solution
Method and system of generating heat by biological
decomposition of organic refuse
Soluble immunoassay reagent comprising lectin covalently bonded
to reactive component
Preservative and fixative preparations for biological systems
Activated apoglucose oxidase and its use in specific binding
assays
Determination of oxidized .alpha.-1-proteinase inhibitor in serum or
plasma
Solvent system for peroxidase inhibitor reagent for fecal occult
blood determinations
Process for cloning the gene coding for a thermostable alpha-
Link to doc.
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amylase into Escherichia coli and Bacillus subtilis
Polysaccharide beads
Microbial degradation of obnoxious organic wastes into innocuous
materials
Dual chamber microplate washer
Method of testing for particular antibodies in the serum of a patient
Method of preserving organ and apparatus for preserving the
same
Process for producing and obtaining anaphylatoxin-and
cocytotaxin-containing leucotaxine preparations and of
anaphylatoxin and cocytotaxin proteins in molecularly
homogeneous, biologically active form
Element for immunoassay
Phosphopeptides from casein-based material
Process for making novel blood clotting enzyme compositions
Isoelectric focussing-polynucleotide/polyacrylamide gel
electrophoresis
Cloned high signal strength promoters
Tricyclic antidepressant drug immunogens, antibodies, labeled
conjugates, and related derivatives
Process for producing target cell lysis factor and uses therewith
Process for producing L-histidine by fermentation
Microbiological process for the preparation of 1-carvone
Plasminogen activator derivatives
Antibiotic complex producing bacterial culture
Process for producing gene products of plasmid having
temperature dependent plasmid copy number
Method of culturing anchorage dependent cells
Tissue culture cluster dish
Apparatus for composting
Method for determining bacterial endotoxin and kit therefor
Immunoassays using support-containing separate antigens and
antibodies derived from an immune complex
Labeled anti-hapten antibodies and their use as a universal
reagent for solid phase radio- and/or enzyme-immunoassays
Chloramphenicol derivatives, antigens and antibodies
Biologically stable alpha-interferon formulations
Erythromycin D and esters thereof
Process for the determination of antithrombin-BM
Detection of HCG with solid phase support having avidin coating
Process for the production of tyramine oxidase
Process for production of cellulase
Microplate washer
Method for enzyme immunoassay and production of antibody
Covalently attached complex of alpha-1-proteinase inhibitor with a
water soluble polymer
Method for obtaining periplasmic proteins from bacterial cells
using chloroform
Microbial leaching of sulphide-containing ores
Method for labeling phagocytic cells
Specimen embedding composition
Method of regulating appetite and efficiency of food utilization
employing interferon
Gene transfer in intact mammals
.beta.-Galactosidase inhibitor GT-2558 and its derivatives
Mycostatic whey and process of manufacture
Fermentation of glucose with recycle of non-fermented
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components
Liquid proteinase concentrate and method for preparation
Immunoassay for Chlamydia trachomatis antigens
Immunoassay for Neisseria gonorrhoeae antigens
Method for purifying gamma-interferon
Assessment of nutritional status of individuals
Chymopapain allergen and method
Antibiotic agents from S. coeruleorubidus, rubidus
Detecting intracellular antigens in swelled and fixed cells with
labeled antibody
Analysis for total cholesterol using lecithin:cholesterol acyl
transferase (LCAT)
Test for esterase activity in a liquid sample
Diagnosing autoimmune rheumatoid arthritis by measuring
proteolytic activity of .alpha..sub.2 -macroglobulin
Method for evaluating mutagenicity
Bacterial production of heterologous polypeptides under the
control of a repressible promoter-operator
Bacteria carrying plasmid having temperature dependent plasmid
copy number
Organic waste bioconverter and method
Angular mold for dental use
Cross-linked protein composition using aluminum salts of acetic
acid
Polyprenyl carboxylic acid derivatives
Radionuclide labeled lymphocytes for therapeutic use
Metachromatic dye sorption and fluorescent light emmisive means
for differential determination of developmental stages of
neutrophilic granulocytic cells and other leukocytes
Influenza vaccine production in liquid cell culture
Cheese with micro-organism--caused decoration on its rind and
process for producing same
Prevention of graft versus host disease following bone marrow
transplantation
Infectious bronchitis virus strain
Culturing Bordetella in media containing etherified cyclodextrin
Plasmids
Flow cytometer for identifying algae by chlorophyll fluorescence
Packing, in particular for transporting and dispatching products, for
example biological products
Charge effects in enzyme immunoassays
Method of preparing immunostimulant proteoglycans which induce
production of interferon, proteoglycans obtained and
pharmaceutical compositions containing them
Bioluminescence method for determining NADH or NADPH
Process for producing a high fructose sweetener, high protein
meal, and cereal germ oils
Article for culturing differentiated cells
23,23-Difluoro-1.alpha.,25-dihydroxy-vitamin D.sub.3
Protein purification process and product
Process for producing a biochemical vaccine against Salmonella
infection
Dermatic medicament
Process for the manufacture of ethyl alcohol from citrus molasses
Open reading frame vectors
Enzyme immunoassay with two-part solution of
tetramethylbenzidine as chromogen
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Method and composition for the determination of cholesterol
Quantitative analysis film
Method for eliminating turbidity in a biological fluid and reagent
therefor
Monomethylamine-oxidizing enzyme
Process for determining the pH value in the interior of a cell
Method of microbial assay
Polyurethane foam and a microbiological metabolizing system
Recombinant cDNA construction method and hybrid nucleotides
useful in cloning
Process for preparing antibiotic AM-2604-A
Method for producing aldehydes from primary alcohols
Anaerobic digestion of organic waste for biogas production
Multifunctional, cloning vectors for use in Streptomyces, Bacillus,
and E. coli
Acetaminophen analogs, antigens, and antibodies
Process for producing supports for cell cultures and supports so
obtained
Stabilized peroxidase compositions
Antibiotics produced by fermentation of a novel strain of
Streptomyces hygroscopicus
Method for producing L-histidine by fermentation
Vermiculite as a carrier support for immobilized biological
materials
Process for crystallizing egg white lysozyme
Cultures of novel strains of Streptomyces
Affinity immunoassay system
Hybridoma tumor cell lines and their monoclonal antibodies to
human colony stimulating factor subclass number 1
Procedure for immunologic determination of procollagen peptide
(type III) and procollagen peptide col 1 (type III) together and a
process for preparing anti-procollagen peptide col 1 (type III)
serum
Alpha-amylase assay and substrates for use therein
Fibrin gel-containing filter of porous material
Method of treating waste liquors containing phenolics and
formaldehyde
Process for separating substances from one another using a fibrin
gel filter
Infectious bronchitis vaccine for poultry
Purified plasminogen activator, process for its production and
thrombolytic composition containing it
Antibiotic 273.sub.a1
Lauter tuns
Heterogeneous immunoassay method
Method for testing microbial degradation of cellulose
Process for preparation of aspartylphenylalanine alkyl esters
Production of organic acids by a continuous fermentation process
Stabilizing and selecting recombinant DNA host cells
Plasmid pAC 1, a process for obtaining it and its use
Multi-layer immobilized enzyme compositions
Hepatitis-A viruses adapted to human fibroblast cells
Modified Pasteurella haemolytica bacteria
Colored molecular weight marker
Pharmacologically active compounds
Method of storing red blood cells which minimizes both red blood
cell hemolysis and exposure to blood extractable plasticizers
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Urea determination method
Determination of collagenase by reacting with peptide substrates
Method for detecting the presence of G.sub.D3 ganglioside
Magnetic separation using chelated magnetic ions
Rat antibody to hCG
Antitumor antibiotics BBM-2040A and BBM-2040B
Virus vaccines and process for preparing the same
Non-sucrose fermenting Pedioccus pentosaceus
Method for culturing cells or tissues
Method for simultaneously monitoring turnover rate in multiple
proteins
Detection of white cell associated bacteria with a fluorescent dye
Biochemical process
Gene splicing method and products produced therefrom
Pseudomonas degradation of hydrocarbons
Method for the separation of extracellular amylase and protease
produced during the fermentation of enzyme producing
microorganisms
Bacteriophage DNA cloning vector TG1 and microorganisms
containing TG1
Molecular cloning vectors for use in gram-negative bacteria
Assay
Anti-streptolysin O latex reagent and process for the preparation
thereof
Recovery of alcohol from a fermentation source by separation
rather than distillation
Reagent for the determination of ristocetin cofactor (v.Willebrand
factor)
Method and apparatus for cryopreparing biological tissue for
ultrastructural analysis
Filter sheet material
Double antibody immunoassays of enzymes such as prostatic acid
phosphatase
Homogeneous enzyme immunoassay with heating step after
incubation, THERESIA
Peptide-type substrates useful in the quantitative determination of
endotoxin
Process for producing fuel grade alcohol by solvent extraction and
carrier gas stripping
Anaerobic digestion process of wastes containing cellulose
Cell labeling with antigen-coupled microspheres
Adenovirus promoter system
Isolation of cyclase, epimerase and a ring expansion enzyme for
producing unnatural cephalosporins
Use of glucose oxime to increase glucose isomerase activity in
bacterial cells
Process for concentrating and purifying human urinary kallikrein
Apparatus for chemical froth suppression in a fermenter
Antibiotic X-14934A
Process for the utilization of household rubbish or garbage and
other organic waste products for the production of methane gas
Process for the continuous rectification of alcoholic fermates
Cooperative enzymes comprising alkaline or mixtures of alkaline
and neutral proteases without stabilizers
Purification and activity assurance of precipitated heterologous
proteins
Purification and activity assurance of precipitated heterologous
proteins
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1-(p-Substituted or unsubstituted aminoalkyl)phenylpropane-1,2dione bis(thiosemicarbazone) derivatives, and their production and
use
Inactivation of a lipid virus
Alpha-lactalbumin contraceptive
Antibiotic substances DC-45, and their use as medicaments
Reagent composition and assay for the determination of .gamma.glutamyltransferase activity
High efficiency eukaryotic metallothionein promoter system
Process for the industrial preparation of collagenous materials
from human placental tissues, human collagenous materials
obtained and their application as biomaterials
Production of high sugar syrups
Process for producing 4-cyclopentenones
Direct fermentation of D-xylose to ethanol by a xylose-fermenting
yeast mutant
Treatment of obnoxious chemical wastes
ATCC HB8116 And its monoclonal anti-H-Y antibody, Hyclonalan
Process for selectively controlling unwanted expression or function
of foreign nucleic acids in animal or mammalian cells
Purification and activity assurance of precipitated heterologous
proteins
Macbecin derivatives and their production
Antibiotic stubomycin and process for the production thereof
Preparation of malt and beer having a low nitrosamine content
Preparation of an antibiotic selectively effective against
staphylococcus infections
Mutant strain of Clostridium thermoaceticum useful for the
preparation of acetic acid
Functionally independent cloning vectors for use in streptomyces
Cloning vectors for use in streptomyces and related organisms
Assay for monoclonal antibody against surface Ig of a human B
cell tumor
Method and apparatus for the detection of toxicants
Bioreactor
Fermentation composition using a selected lactobacillus
Method for testing microbial interaction with growth affecting
substances
Process for producing alcohol by fermentation without cooking
Modified live pseudorabies viruses
Hybrid cell lines producing monoclonal antibodies directed against
Treponema
Cell culture using a monolithic support
Cell growth on liquid-liquid interfaces
Method for cultivation of microorganism
Composite plasmid
Monoclonal antibody mixtures and use thereof for enhanced
sensitivity immunoassays
Method for the identification and purification of human lung tumorassociated antigens (hLTAA) and clinical detection and
determination of these antigens
Assay for interferon
Assaying for a multiplicity of antigens or antibodies with a
detection compound
Method for the diagnosis of Legionnaires' disease
Aggregating polysaccharide derived from aureobacidium
Highly viscous polysaccharides
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Compositions containing odor purified proteolytic enzymes and
perfumes
Compounds for determining the pH value in the interior of a cell
Method for carrying out analytical determinations
Immunoassay of terminal deoxynucleotidyl transferase
Process for the production of disaccharide-tripeptide and
disaccharide-tetrapeptide
Fermentation process
Hybrid cell line for producing complement-fixing monoclonal
antibody to human T cells
Hybrid cell line for producing monoclonal antibody to human T
cells
Hybrid cell line for producing monoclonal antibody to human
helper T cells
Antibiotics KA-6606 XII, XIII, XV, XVI and XVII
Compositions containing and methods of use of an infectivitycured Hr plasmid-bearing microorganism
Reduced biodegradability in a polymer flood process
Novel antibiotic 76-11, process for the production thereof,
anticoccidiosis agent and domestic animals growth accelerator
comprising the same as an effective ingredient
Method and reagent for the enzymatic determination of enzyme
substrates
Solid phase system for ligand assay
Monoclonal antibodies for human tissue cross-matching
Method for enzyme immunoassay and peptide-enzyme conjugate
and antibody therefor
Biological detection process using polymer-coated electrodes
Method and apparatus for testing microbial interaction with growth
affecting substances
High yield process for in vitro production of serum-free and
mitogen-free interleukin-2 using a roller bottle culture system
Human antithrombin III
Hyaluronic acid from bacterial culture
Antibiotic acmimycin and its production
Method for the preparation of physiological effectors
Process for producing fuel grade ethanol by continuous
fermentation, solvent extraction and alcohol separation
Acetylesterases
Plasmid pSAN 181
Specific binding assays utilizing analyte-cytolysin conjugates
Production of viral antigens
Multiple reactor system and method for polynucleotide synthesis
Wine fermentation apparatus
Purification and activity assurance of precipitated heterologous
proteins
Reagent test device holder
Imparting low- or anti-cariogenic property to orally-usable products
Human recombinant interleukin-2 muteins
BBM-2478 Antibiotic complex
DNA promoter sequence of Avian tumor virus and use thereof for
enhanced gene expression in E. coli
In vitro enzymatic process for preparing glucuronides of estercontaining anticholinergics
Production of L-amino acids by transamination
Immobilized biocatalysts
Aqueous compositions containing stabilized enzymes
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283
4,518,695
284
285
286
287
288
289
290
291
292
293
4,518,696
4,518,697
4,518,698
4,519,934
4,519,959
4,519,984
4,520,016
4,520,020
4,520,100
4,520,101
294
295
296
4,520,102
4,520,103
4,520,104
297
298
4,520,105
4,520,106
299
4,520,107
300
4,520,111
301
4,520,113
302
303
304
305
306
307
4,520,226
4,520,821
4,521,252
4,521,339
4,521,349
4,521,376
308
309
4,521,407
4,521,408
310
311
312
4,521,434
4,521,509
4,521,510
313
314
315
4,521,511
4,521,512
4,521,513
316
4,521,514
317
4,521,515
318
319
4,521,516
4,521,517
320
321
4,521,518
4,522,261
322
4,522,786
323
4,522,809
Process for eluting egg white lysozyme
Stabilized liquid bacterial suspension for oral administration to
animals
Acid stable protease from mutants of genus Aspergillus
Plasmid and production thereof
Liquid enzyme concentrates containing alpha-amylase
Gas-liquid contacting apparatus
Apparatus for carrying out sparged reaction
Bacteriolytic proteins
Method of preventing virus increase in plants
Method for measuring thrombin
Production of cephalosporin C
Microbial process for producing 12.alpha.-hydroxypregna-1,4-dien3-one-20.alpha.-carboxylic acid
Microbial production of indigo
Production of butanol by a continuous fermentation process
Process for production of sugars and optionally cellulose and
lignin from lignocellulosic raw materials
Tartrate catabolism gene
Tissue culture and cell growth-promoting material and its method
of manufacture
Diagnostic method for determining content of sialic acid or
sialoprotein
Serological detection of antibodies to HTLV-III in sera of patients
with AIDS and pre-AIDS conditions
Treatment of graft versus host disease using a mixture of Tlymphocyte specific monoclonal antibody: ricin conjugates
Growing of long-term biological tissue correction structures in vivo
Process for producing a high-purity isomaltose
Ansatrienols
Fluid diffuser for gases and liquids
Glutaraldehyde indicator
Treatment of acquired immune deficiency syndrome with thymus
extract
Antibiotics-859A and production thereof
Fermentation method and compositions including a lactobacillus
species strain
Method for degrading DNA
Hybridoma cell lines and monoclonal antibodies to theophylline
Catalyzed colorimetric and fluorometric substrates for peroxidase
enzyme determinations
Microorganism identification technique
Protection against dental caries
Process for producing an addition compound of a dipeptide ester
and an amino acid ester
Bacterial strain for purifying hydrocarbons pollution and purification
process
Strain of Clostridium acetobutylicum and process for its
preparation
Compost aeration system
Multi-purpose blood diluent and lysing agent for differential
determination of lymphoid-myeloid population of leukocytes
Biosurfactant and enhanced oil recovery
Multilayered test device for detecting analytes in liquid test
samples
Process for obtaining lipid envelope virus sub-units, notably
antigens for use as vaccines, the products obtained and their
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324
325
4,522,810
4,522,832
326
4,522,918
327
328
329
330
331
332
333
334
335
336
337
338
4,522,919
4,522,920
4,522,922
4,522,923
4,522,924
4,523,999
4,524,025
4,524,133
4,524,134
4,524,135
4,524,136
4,524,137
339
340
4,524,145
4,524,198
341
4,525,218
342
4,525,265
343
4,525,349
344
345
4,525,351
4,525,354
346
4,525,452
347
348
4,525,453
4,525,454
349
350
351
352
4,525,455
4,525,456
4,525,457
4,525,458
353
354
355
356
4,525,465
4,525,704
4,526,753
4,526,782
357
358
4,526,791
4,526,865
359
360
361
4,526,866
4,526,867
4,526,868
362
363
364
4,526,871
4,528,159
4,528,199
applications
Feline calicivirus vaccine
Lactase-containing baking formulations
Process for producing monoclonal antibodies reactive with human
breast cancer
Method of producing antibacterial agents and bioconverting
microorganism therefor
Production of ethanol
Soluble assay
Self-contained assay method and kit
Immobilized enzyme composite/process using a mica carrier
Ultrafiltration method
Hybridoma cell lines and monoclonal antibodies to theophylline
Test device for lactase activity in a meconium sample
Process for preparing 1,2-dehydro steroids
A-21978C cyclic peptides
Process for preparing a cosmetic material
Preparation of catalysts for biochemical conversion reactions
4'-Deschlororebeccamycin pharmaceutical composition and
method of use
Poly(1,2-disubstituted cyclohexa-3,5-dienes
Selective hydrolysis of cellulose to glucose without degradation of
glucose using zinc chloride
Electrochemical sensor capable of determining hydrogen peroxide
concentration and analyzer using the same
Process for the large-scale production of a vaccine against
poliomyelitis and the resulting vaccine
Liquid adherent disinfectant compositions for topical application
and method of preparation
Antibiotic and process for the production thereof
Enzyme immunoassay with step of immersing sample in deionized
water
Process for rapidly differentiating between gram-negative and
gram-positive microorganisms
Production of L-4-phenyl-2-aminobutanoic acid by transamination
Method for preparing a cell free homogenate of Chrysanthemum
cinerariaefolium (Trev.) Bocc. containing enzymes and methods of
use
Support matrix and immobilized enzyme system
Method of immobilizing enzymatically active materials
Method for the production of sphingomyelinase
Water-insoluble biospecific absorbent containing argininal
derivative
Enzymatic toxic gas sensor
Multiple profile reagent card
Process for recovering interferon
Bioconversion of agricultural wastes into proteinaceous animal
feed
Microorganism identification technique
Angiotensin I-converting enzyme inhibitor and preparation of the
same
Process for preparing immobilized microorganism
Rennet substitute from seals for making cheese
Conjugate obtained by coupling a lectin and a specific ligand,
containing such a conjugate and its applications in biology
Automated analysis instrument system
Silage production from fermentable forages
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365
366
4,528,265
4,528,266
367
368
4,528,267
4,528,268
369
4,528,269
370
4,528,270
371
372
373
374
375
4,528,271
4,528,272
4,528,273
4,528,369
4,529,542
376
377
4,529,693
4,529,694
378
379
380
381
4,529,695
4,529,696
4,529,697
4,529,698
382
4,529,699
383
4,529,700
384
385
386
387
388
389
390
391
4,529,701
4,529,702
4,529,709
4,529,734
4,529,797
4,530,763
4,530,784
4,530,786
392
393
394
395
396
397
398
4,530,787
4,530,790
4,530,831
4,530,834
4,530,835
4,530,846
4,530,900
399
400
4,530,901
4,530,902
401
402
403
4,530,903
4,530,904
4,530,905
404
405
4,530,906
4,530,907
406
4,530,908
Processes and products involving cell modification
Method of inserting unique DNA sequences into DNA vectors
Fluorometirc enzyme inhibition immunoassay for measuring
potency of allergen extracts
Apparatus and method for testing the sufficiency of sterilization
Method for producing single and/or mixed strain concentrates of
bacteria
Electrochemical method for detection and classification of
microbial cell
Process for the intensification of microbiological conversions of
steroids using cyclodextrin additives
Fermentation of bile
Microorganism strains for the fermentative preparation of L-serine
20-Dihydro-20-deoxy-23-de(mycinosyloxy)tylosin
Novel proteinous substance KUD-PC and its production
Detecting neoplastic mammary epithelial cells by detecting
thioesterase II marker
Cell fusion
Recombinant cloning vector, host for the vector, and method for
using same
Process for liquefaction of starch
Process for producing L-glutamic acid by fermentation
Process for preparing a 2-oxo-1-azetidinesulfonic acid salt
Process and installation for obtaining ethanol by the continuous
acid hydrolysis of cellulosic materials
Hybridoma cells secreting a monoclonal antibody specific for 5bromo and 5-iodoeoxyuridine and reagents for measuring cellular
proliferation
Product and process for stimulating bacterial action in an
anaerobic digestion system
Transport medium for microorganisms
Method for determination of 5-aminosalicylic acid
2-formyloxymethyl-clavam
Heteropolysaccharide S-198
Method for treating waste fluid with bacteria
Large scale extraction process for contact inhibitory factor
Antibody for the detection and quantification of atrazine
Controlled oxidation of microbially produced cysteine-containing
proteins
Cholecystokinin antagonists
Infectious Bursal Disease vaccine
Preparation of an entomopathogenic fungal insect control agent
CL-1577 Antibiotic compounds and their production
Method for the production of selenium yeast
Soluble insoluble polymers in enzymeimmunoassay
Recombinant DNA molecules and their use in producing human
interferon-like polypeptides
Method for producing fructose-1,6-diphosphoric acid
L-2-hydroxy-4-methylpentanoic acid-dehydrogenase, process for
obtaining it and its use
Method for conferring bacteriophage resistance to bacteria
Crosslinked gelatin foams
Microbial rennet having increased milk coagulating activity and
method and method for production thereof
Perfusion-cultivation of animal cells and equipment therefor
Diagnosis and treatment of fluke infections with monoclonal
antibodies
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407
4,532,203
408
4,532,204
409
410
4,532,205
4,532,206
411
412
413
4,532,207
4,532,208
4,532,209
414
4,532,210
415
4,532,211
416
417
418
419
420
421
422
423
4,532,212
4,532,213
4,532,214
4,532,215
4,532,220
4,532,232
4,532,733
4,533,359
424
4,533,493
425
4,533,496
426
4,533,547
427
428
429
430
431
432
433
434
435
436
437
438
439
4,533,548
4,533,628
4,533,629
4,533,630
4,533,631
4,533,632
4,533,633
4,533,634
4,533,635
4,533,636
4,533,637
4,533,638
4,534,483
440
441
4,534,864
4,534,965
442
4,534,970
443
4,534,971
444
445
4,535,057
4,535,058
446
447
4,535,059
4,535,060
Fluorescent determination of microlymphocytotoxicity
Mutation assays involving blood cells that metabolize toxic
substances
Process for the injection of very small amounts of samples into
cells
.beta.-Streptococcus selective medium
Process for the preparation of polypeptides utilizing a charged
amino acid polymer and exopeptidase
Constitutive glucose isomerase producer
Production of para-cresol
Process for producing hydrogen by alga in alternating light/dark
cycle and environmental aerobic/microaerobic conditions
Coliform bacillus having a gene for the production of
staphylokinase and a process for production of staphylokinase
therewith
Process for the dissolution of peptides in non-aqueous and mixed
non-aqueous/aqueous systems
Recovery of acid fungal protease
Method for isolation of aminoacylase
Isolation of hepatitis A virus strain HM-175
Assays for the determination of carcinogenicity
Lectin-containing separation agent
In vitro propagation of grape
Process for modifying animal fibers
Theophylline immunogens, antibodies, labeled conjugates, and
related derivatives
Method of isolating monoclonal antibodies from hybridoma
cultures
Antiviral antibiotic substance AM-2722 and process for production
thereof
Acidic polysaccharide CH-1 isolated from Chlorella pyrenoidosa
and the use thereof
Colony hybridization method
Simultaneous calibration heterogeneous immunoassay
Toxins and antibodies of C. difficile
Fermentation process for preparation of antibiotic Bu-2517
Production of a cephalosporin by fermentation
Process and apparatus for isomerizing glucose to fructose
Tissue culture medium
Process for stimulating the growth of epidermal cells
Medium for plant protoplast culture
Culture medium
Blood typing apparatus
Culture flask closure
Process and device for the regeneration of a group of solid
particles having a coating of a biological material
Controlling plant fungi using streptomycetes grown on chitin
Antibacterial antibiotics LL-CO8078.alpha..sub.1, .alpha..sub.2,
.alpha..sub.3 and .beta.
Complexation of anthracycline and anthraquinone antibiotics by
the apo riboflavin binding protein from eggs
Immunoassay employing monoclonal herpes simplex antibody and
biotin-avidin detection system
Characterization of oncogenes and assays based thereon
Muconic acid productivity by a stabilized mutant microorganism
population
Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthetase,
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448
449
4,535,061
4,535,062
450
451
452
453
454
455
4,535,083
4,535,153
4,536,391
4,536,397
4,536,474
4,536,475
456
457
458
459
460
4,536,476
4,536,477
4,536,479
4,537,715
4,537,763
461
462
463
464
465
4,537,764
4,537,777
4,537,790
4,537,852
4,537,858
466
467
468
469
470
4,537,859
4,537,860
4,537,956
4,537,957
4,539,182
471
4,539,201
472
473
4,539,203
4,539,292
474
475
476
477
4,539,293
4,539,294
4,539,295
4,539,333
478
479
480
4,540,506
4,540,517
4,540,549
481
482
483
484
485
4,540,565
4,540,575
4,540,659
4,540,660
4,540,661
486
487
488
489
490
4,540,662
4,540,663
4,540,664
4,540,665
4,540,666
production and use
Bacteria capable of dissimilation of environmentally persistent
chemical compounds
Apparatus for growing microorganisms
Cleavage products of 4',6'-didesoxy-4'-thio-,6'-amino-hepturonic
acid nucleosides
Heteropolysaccharide S-88
Process for preparing urokinase complex
Antibiotics, neoviridogriseins, and their method of production
Tissue culture of lichens
Plant vector
Stable epimerase reagent, cyclase reagent and ring expansion
reagent for cell-free production of cephalosporins
Thermostable glucoamylase and method for its production
Use of anti-idiotype antibodies in immunoassays
Glycopeptide antibiotic CUC/CSV and process for its production
Products sweetened with .alpha.-glycosyl glycyrrhizin
Stabilized enzymatic dentifrice containing B-D-glucose and
glucose oxidase
A52688 Antibiotics and process for their production
Process for growing cell cultures of diploid cells on cell supports
Process for the production of human urokinase
Plastatin
Process for preparing 3-hydroxy-ML-236B derivatives known as
M-4 and M-4'
Static cell culture maintenance system
Antibiotics X-14889 A, C and D
Process for the production of mycaminosyltylonolide
Automated reagent blotter
Medicament and method for inducing immunity to infectious
bovine keratoconjunctivitis
CL-1577D And CL-1577E antibiotic/antitumor compounds, their
production and use
Immunoassay technique for specific immunoglobulin E
Production of butanol by fermentation in the presence of
cocultures of clostridium
Immobilization of proteins on polymeric supports
Binary kinetic assay method and apparatus
Prostacyclin, methods of using and method of making
Composition for cleaning drains clogged with deposits containing
hair
Antibiotic TAN-420
Chemical analyzing apparatus
Reduced IgG in low ionic strength medium for immunohematologic
agglutination
Choline oxidase inhibitor
Simultaneous calibration heterogeneous immunoassay
Substrate for fluoroimmunoassay of biological fluids
Composition of matter and process
Semisynthetic macrolidic antibiotics, intermediate compounds for
their preparation and related pharmaceutical compositions
containing compounds for their preparation and related
pharmaceutical compositions containing them
Liquefaction of starch
Method of saccharifying cellulose
Process for producing D-.beta.-hydroxyalkanoic acid
Methane fermentation
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491
492
493
494
495
496
4,540,667
4,540,668
4,540,669
4,540,670
4,541,952
4,541,953
497
4,542,096
498
4,542,097
499
500
4,542,098
4,542,099
501
502
4,542,100
4,542,101
503
504
505
4,542,102
4,542,154
4,542,683
506
4,543,212
507
508
509
510
511
512
513
4,543,236
4,543,252
4,543,259
4,543,325
4,543,326
4,543,327
4,543,328
514
515
516
4,543,329
4,543,330
4,543,331
517
518
4,543,332
4,543,333
519
4,543,334
520
521
4,543,335
4,543,338
522
523
4,543,339
4,543,350
524
4,543,439
525
526
4,544,381
4,544,546
527
528
529
4,544,552
4,544,558
4,544,629
530
531
4,544,630
4,544,631
Fluorescent siderophore genes
Alcohol oxidase from Pichia-type yeasts
Herpes simplex type I subunit vaccine
Method for measurement of liquid samples
Purification method of human interferon
Preparation of anti-T-lymphocyte globulin
Detecting rearranged human c-myc DNA fragments associated
with oncogenes
Production of gamma-lactone, rich flavor additives by
Pityrosporum species cultured on lipid rich substrates
Production of glucose dehydrogenase and use of the resultant
enzyme in the enzymatic synthesis of L-carnitine
Method for manufacturing restriction enzymes from Bifidobacteria
Strain of Pseudomonas putida for producing an intermediate
compound in the production of para-cresol
Process for the cultivation of matrix-bound biologic cell systems
Coupling of nucleic acids to solid support by photochemical
methods
Antibiotic compound
Brewing apparatus
Xeronine, a new alkaloid, useful in medical, food and industrial
fields
Incubating apparatus for selective and exact treatment of
histological preparations
Cationic oligopeptides having microbicidal activity
Substance TH69E and immunopotentiator containing the same
Process and reagent for the determination of creatinine
Stabilization of oxidase
Malate dehydrogenase method
Process for detecting pathogens
Process for the specific cleavage of protein sequences from
proteins
Process for the production of a fermentation starting material
Fermentative or enzymatic production of 2-keto-L-gulonic acid
Method for the preparation of spherical microorganism cell
aggregates
Liquid proteinase concentrate and method for preparation
Streptomyces capable of producing neutral macrolide antibacterial
agents
Device and method for the quantitative determination of heparin in
mammalian blood plasma
Wipe-off test device
Early pregnancy detection by detecting enhanced blood platelet
activation
Carcinostatic agent
Production and use of monoclonal antibodies to phosphotyrosinecontaining proteins
Process for removal of emission gas pollutants by biological
means
Fluorescent nucleic acid stains
Process for the preparation of cell and tissue regenerating
substances
Process for preparing carbohydrates from vegetal juice
Receptor-based histamine assay
Process for specific determination of cholesterol in the presence of
the HDL fraction in serum
Process and reagent for the determination of .alpha.-amylase
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532
4,544,632
533
534
4,544,633
4,544,634
535
4,544,635
536
537
4,544,636
4,544,637
538
4,544,638
539
540
541
542
543
544
545
546
4,544,640
4,545,147
4,545,382
4,545,831
4,545,909
4,545,945
4,545,986
4,545,987
547
548
549
550
551
552
553
554
4,545,988
4,545,991
4,546,076
4,546,077
4,546,078
4,546,079
4,546,080
4,546,081
555
556
557
558
559
560
561
562
563
564
565
566
567
4,546,082
4,546,083
4,546,084
4,546,085
4,546,086
4,546,095
4,546,161
4,546,500
4,547,226
4,547,280
4,547,367
4,547,368
4,547,373
568
569
4,547,374
4,547,460
570
4,547,461
571
572
4,547,462
4,547,463
573
574
575
4,547,465
4,547,523
4,547,569
Human T cell lines and method of producing same
Process for producing vitamin B.sub.12 by the fermentation
technique, and vitamin B.sub.12 -producing microorganism
Method of producing acyclovir
Preparation of optically active cis-1,3-dibenzyl-hexahydro-1Hfuro[3,4-d]imidazole-2,4-dione and its intermediates
Starter cultures of improved activity for dairy products and process
of making same
Culture media from clarified diary whey lactose permeates
Synthesis of cross-links in the helical domain of collagen using
pyridoxal 5-phosphate and copper or iron
Anti immune complex antibody for determining SLE, rheumatoid
arthritis or tetanus
Asexual embryogenesis of callus from theobroma cacao L.
Sensor for components of a liquid mixture
Method for transferring a thin tissue section
Growth of biomass
Process for improving the gas distribution in air-lift loop reactors
Timothy grass antigen specific anti-idiotypic antibodies
Psoralen inactivated double-stranded RNA viral vaccines
Urokinase-plasmin complex adsorbable by fibrin and process for
preparing same
Difficidin and derivative antibacterials
Enzymatic process for the determination of beta-lactam antibiotics
Leucine dehydrogenase and a process for production thereof
Polymer containing biocatalyst
Streptomyces species and process for producing antibiotic
Manufacture of halogenated ketones and aldehydes
Continuous alcohol fermentation process using immobilized yeast
E. coli/Saccharomyces cerevisiae plasmid cloning vector
containing the alpha-factor gene for secretion and processing of
hybrid proteins
Method and device for cell culture growth
Biologically pure culture of Actinomadura Sp.
Cell cultivation container
Microbial culture apparatus
Use of fructose-1,6-diphosphate for treating myocardial infarction
Media for affinity chromatography
Fabrication of living blood vessels and glandular tissues
Preparation of high fructose syrups from citrus residues
Maltose sensor
Hepatitis B core antigen vaccine
Hepatitis B core antigen vaccine made by recombinant DNA
Wine preparation with new strains of Leuconostoc oenos
Saccharomyces species FD 612 and the utilization thereof in
bread production
Multizone analytical element and method for analyte determination
Composition, analytical element and method for the quantification
of creatine kinase
Process for preparing substance having carcinostatic and
immunostimulating activity
Method of immobilizing microorganisms
Analytical element having improved spreading zone and method of
use
Polyether antibiotic from streptomyces
Intercalating agents specifying nucleotides
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576
577
578
579
580
581
4,548,727
4,548,802
4,548,803
4,548,816
4,548,900
4,548,901
582
583
584
4,548,906
4,548,909
4,548,974
585
586
587
588
589
4,549,011
4,550,016
4,550,017
4,550,019
4,550,021
590
591
592
4,550,075
4,550,076
4,550,077
593
4,550,078
594
595
596
4,550,079
4,550,080
4,550,081
597
598
599
600
4,550,085
4,550,086
4,550,159
4,550,528
601
602
603
604
4,551,272
4,551,275
4,551,307
4,551,425
605
4,551,426
606
4,551,427
607
608
609
4,551,428
4,551,429
4,551,430
610
611
612
613
614
615
616
617
4,551,431
4,551,432
4,551,433
4,551,482
4,551,529
4,551,533
4,552,060
4,552,145
618
4,552,633
Aqueous compositions containing stabilized enzymes
Continuous flow separation with moving boundary sorption
Continuous flow separation with moving boundary sorption
Antibiotic SF-2288 and its preparation method
Method of interferon production
Plantlet generation by cell culture
Integral multilayer analytical element for the analysis of ammonia
or an ammonia forming substrate and a method for the detection
thereof using the same
Method of diagnosis
Antibiotics produced by Kibdelosporangium aridum shearer
Modified sheet of material and method of making and using same
in connection with biochemical procedures
Composite cytologic counterstain formulation
Fluorescence screening for blood typing
Manufacture and use of fowl egg antibodies
Antitumor antibiotic 81-484 and process for its production
Method for ligand determination utilizing an immunoassay
monitorable by biotin-containing enzymes, and compositions
therefor
Rapid assaying method for guanase
.beta.-Amylase determination
Method for the quantitative determination of individual polyamine
components in a mixture
Determination of L(+)-tartrate or D(+)-malate with L(+)-tartrate
dehydrogenase
Process for the preparation of a plasminogen activator
Non-reverting salmonella
Method of detecting or determining histamine in histamine
containing materials
Monoclonal antibodies that recognize human T cells
Anthracycline compounds
Asexual propagation of pine trees
Derivatives of dipeptide and their use in determining the activity of
carboxypeptidase A
Desmethylimipramine derivatives and poly(amino acid) conjugates
Analytical element
Pyroelectric gas sensor
Heterogeneous immunoassay for digoxin using ouabain as a
separation means
Process and reagent for the determination of blood glucose in
haemolysed whole blood
Agent for the determination of esterolytic and/or proteolytic
enzymes
Stimulation of antigen production by Bordetella pertussis
Constitutive producer of a thermostable glucose isomerase
The use of gallium and indium salts for the immobilization of
proteins
Paracoccus denitrificans, FUM-14: a fumarase overproducer
Microbial hybrid promoters
Macroporous, hydrophilic enzyme carrier
Guanine-N.sup.7 -oxide
Antibiotic LL-D42067.alpha.
Apparatus for the continuous boiling of wort
Nerve identification method
Fine particulate for use in clinical testing and a process for
producing thereof
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619
4,552,757
620
4,552,758
621
4,552,760
622
4,552,761
623
624
4,552,812
4,552,840
625
626
4,552,841
4,552,842
627
628
629
630
4,552,843
4,552,844
4,552,845
4,552,846
631
4,552,867
632
633
634
4,553,990
4,554,075
4,554,157
635
4,554,158
636
637
638
639
4,554,159
4,554,162
4,554,165
4,554,248
640
4,554,249
641
642
643
644
645
646
647
4,554,250
4,554,251
4,554,252
4,554,253
4,554,256
4,554,289
4,555,396
648
4,555,402
649
650
651
4,555,483
4,555,484
4,555,485
652
653
4,555,486
4,555,487
654
655
656
657
658
4,556,073
4,556,460
4,556,556
4,556,634
4,556,635
Use in an animal host and precursors for vaccines utilizing avianhuman reassortants to combat influenza A virus
Human use of avian-human reassortants as vaccines for influenza
A virus
Method for stabilizing tissue plasminogen activator and a stable
aqueous solution or powder containing the same
Method for influencing the immune systems of mammals using
leukorecruitin
Process for the production of polyacrolein microspheres and
grafted microspheres
Enzyme electrode and method for dextran analysis
N-Acetyl-.beta.-D-glucosaminides for determining N-acetyl-.beta.D-glucosaminidase activity
Process for producing rebeccamycin
Process for producing an acidic polycyclic ether antibiotic by
cultivation of a novel strain of Streptomyces endus subspecies
aureus
Plant growth medium
Method for separating lysozyme from egg-white
Aspartase from a Bacillus subtilis
Antibiotic LL-BO1208.alpha. and LL-BO1208.beta., process of
preparation, pharmaceutical composition and method of use
Device for separating gaseous and liquid components from a
foamy gas liquid mixture
Process of degrading chloro-organics by white-rot fungi
Hepatitis B vaccine
Modified live sendai virus vaccine for administering through an
aerosol and method of producing the same
Vaccine and method of immunizing against herpes simplex virus
(types 1 and 2)
CL-1724 Antibiotic compounds, their production and use
Method of making cheese with proteinase negative lactic bacteria
Composition and method for detecting Antistreptolysin O
Method for the quantitative determination of physiological
components in biological fluids
Method of increased production of penicillin acylase and plasmid
employed therein
Process and medium for culturing ant venom gland cells
Plant tissue cultivation process
Apparatus for synthesizing adenosine-5'-triphosphate
Antigen associated with early detection of mammalian pregnancy
OF4949
Use of pyrylium and thiapyrylium compounds as biological stains
Physiologically active substance K-252, process for producing
same and pharmaceutical composition containing same
Methods, compositions and elements for the determination of
lipase
Analytical element and method for alkaline phosphatase assay
Production of edible protein containing substances
Method for using an amino-terminus DNA sequence to synthesize
a specific double-stranded DNA
Method for cultivation of Pseudomonas bacteria
Process for reduction of nitrate content of tobacco by microbial
treatment
Dehydration of ethanol
Vaccine for the prevention of vesicular stomatitis virus infection
High sensitivity assay method
Determination of alcohol content in water imiscible organic
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659
4,556,636
660
661
662
4,556,637
4,556,638
4,556,639
663
664
665
4,556,640
4,556,643
4,557,186
666
667
668
669
670
671
4,557,280
4,557,862
4,557,863
4,557,901
4,557,927
4,557,931
672
673
674
675
4,557,933
4,558,004
4,558,005
4,558,006
676
677
4,558,007
4,558,008
678
4,558,009
679
4,558,010
680
4,558,011
681
682
4,558,012
4,558,013
683
684
685
4,558,130
4,558,739
4,559,109
686
687
4,559,120
4,559,142
688
689
4,559,221
4,559,229
690
691
4,559,298
4,559,299
692
693
694
695
4,559,300
4,559,301
4,559,302
4,559,303
696
4,559,304
systems
Composition, analytical element and method for the detection of
bacteria
Immobilized cholinesterase enzyme preparations and a process
for the preparation thereof
Microorganism capable of degrading phenolics
Method and apparatus for dislodging cultured cells
Stabilized test composition, device and method for the
determination of peroxidatively active substances
Assay method and probe for polynucleotide sequences
Brewing apparatus
Process for reduction of nitrate and nicotine content of tobacco by
microbial treatment
Rhodamine derivatives as fluorogenic substrates for proteinases
Device for collection of proteins in a urinal and method of use
Analytical element
Food products and process for producing same
Antigenic compositions and methods for using same
Antibiotic called "chloropolysporin", a process for its preparation,
and its therapeutic and veterinary use
Monitoring preneoplastic antigen
Monoclonal anti-erythropoietin
A.T.C.C. HB8209 and its monoclonal antibody to erythropoietin
Process for detecting LDH.sub.k isozyme activity in human serum
for use as a diagnostic aid and for monitoring response to cancer
therapy
Process for production of A-51568B antibiotic
Process for producing antibiotic A-51568 by fermentation and
microorganism
Recombinant deoxyribonucleic acid which codes for plasminogen
activator and method of making plasminogen activator protein
therefrom
Method for preparation of pure hepatitis B surface antigen from
human plasma
Method and member for detecting and/or measuring the
concentration of a chemical substance
Calibrated reaction measurement system
Fluorogenic dihydroquinolone and dihydrocoumarin indicators for
hydrogen peroxide
Situ microbial plugging process for subterranean formations
Dehydration of alcohol with extractive distillation
Agarose gel electrophoresis technique for the determination of
amylase isoenzymes
Split feed for the anaerobic biological purification of wastewater
P-Glyoxyloylphenylalkanoic acid bis(thiosemicarbazone)
derivatives, and their production and use
Avian proventriculitis vaccine
Cryopreservation of biological materials in a non-frozen or vitreous
state
Cytotoxicity assays in cell culturing devices
Method for using an homologous bacillus promoter and associated
natural or modified ribosome binding site-containing DNA
sequence in streptomyces
Process for preparing macrocin derivatives
DNA for directing transcription and expression of structural genes
Carrier composed of particulate polymer
Substratum for cell culture and a method for culturing and isolating
cells using same
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697
698
699
700
701
702
703
704
705
706
707
708
4,559,305
4,559,306
4,559,307
4,559,308
4,559,310
4,559,313
4,560,479
4,560,504
4,560,509
4,560,647
4,560,648
4,560,649
709
710
711
712
713
714
715
716
4,560,650
4,560,651
4,560,652
4,560,653
4,560,654
4,560,655
4,560,656
4,560,657
717
718
719
720
4,560,658
4,560,659
4,560,660
4,560,661
721
4,560,662
722
723
724
725
726
727
728
4,561,961
4,561,974
4,562,003
4,562,020
4,562,043
4,562,045
4,562,051
729
730
731
732
4,562,070
4,562,077
4,562,147
4,562,148
733
734
735
736
737
738
739
4,562,149
4,562,150
4,562,151
4,562,152
4,562,153
4,562,154
4,562,155
740
741
742
743
744
4,562,156
4,562,157
4,562,159
4,562,160
4,562,245
Microbial culture system
Modified Pasteurella multocida bacteria
Treatment of yeast cells with proteolytic enzymes
Corynebacterium plasmid and vector
Assay methods and systems utilizing mast cell clones
Removal of inorganic contaminants from catalysts
Process for preparing biomass attached to a carrier
Carboxyl anchored immobilized antibodies
Antibiotic A39079 factor S-1
Antibody/antigen determination method
Homogeneous enzyme immunoassay for ferritin
Assaying for hLH or hCG with immobilized hormone receptors
Method and compositions for determination of gamma glutamyl
transpeptidase
Debranching enzyme product, preparation and use thereof
Process for producing L-tryptophan by fermentation
Process for preparing L-aspartic acid
Method for producing L-lysine by fermentation
Serum-free cell culture medium and process for making same
Production of .gamma.-decalactone
Microbiological production of alkylene oxides
Production of butanol by fermentation in the presence of carbon
monoxide
Ethanol production from fermentation of sugar cane
Fixation support for microorganisms
Process for purifying enzymes
Streptomyces antibioticus ATCC 31771 and process for obtaining
same
Cooled microscope slide and electrode apparatus for use in live
cell fusion system
Apparatus for the anaerobic filtration of waste water
Monoclonal antibodies against alveolar surfactant protein
Process for producing self-supporting glucan film
Self-contained swab cartridge apparatus for detecting occult blood
Carrier for holding analytical samples
Generation of anaerobic or microaerophilic atmosphere
Method of enhancement of piliated phase of Bordetella
bronchiseptica
Method for converting malic acid to lactic acid in wine
Method and kit for diagnosis of pseudorabies
Analytical element and method for preventing reagent migration
Yeast culture containing S-adenosyl methionine in high
concentrations, and process for production of S-adenosyl
methionine
Method for manufacture of cellulase
Stabilization of L-phenylalanine ammonia-lyase enzyme
Process for obtaining pure L-leucine
Process for the separation of L-leucine and L-isoleucine
Continuous alcohol manufacturing process using yeast
Hybrid viral plasmid and microorganisms containing same
Mutant microorganism and its use in removing organic sulfur
compounds
Diagnostic device incorporating a biochemical ligand
Diagnostic test for hepatitis B virus
Melanoma tumor antigen and autologous antibody
Extraction process
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745
4,563,303
746
747
4,563,304
4,563,331
748
749
4,563,349
4,563,356
750
751
4,563,417
4,563,418
752
4,563,419
753
4,563,420
754
4,563,421
755
4,563,422
756
757
758
759
4,563,423
4,563,424
4,563,425
4,563,426
760
4,563,462
761
4,563,485
762
4,564,444
763
4,564,453
764
4,564,472
765
766
767
768
769
770
771
772
773
774
4,564,532
4,564,592
4,564,593
4,564,594
4,564,595
4,564,596
4,564,597
4,565,552
4,565,635
4,565,643
775
776
777
778
779
780
781
4,565,687
4,565,688
4,565,696
4,565,697
4,565,699
4,565,780
4,565,781
782
783
784
785
4,565,782
4,565,783
4,565,784
4,565,785
Method for purification of filamentous hemagglutinin
Pyridine compounds modifying proteins, polypeptides or
polysaccharides
System for measuring bioluminescence flash kinetics
Superoxide dismutase, its immobilized form, and their production
and use
Lactic acid fermentation products of sunflower seed milk
Nucleic acid hybridization assay employing antibodies to
intercalation complexes
Process for detection of selected motile organisms
Detection of microbial nucleic acids by a one-step sandwich
hybridization test
Process for assaying the activity of tissue plasminogen activator,
and kit suitable for use in said process
Method for determining the presence of endohydrolase in a liquid
and composition therefor
Method and composition for the removal of ascorbic acid from
aqueous liquids
Products displaying the antigenicity of hepatitis B virus e antigens
and methods of producing those antigens
Method and means for somatostatin protein conjugate expression
Enzyme reaction method for isomerization of glucose to fructose
Process for producing biotin-vitamers
Substance AX-2, a process for producing the same and an
antitumor composition containing the same
Injection-resistant materials and method of making same through
use of nalidixic acid derivatives
Filamentous microorganism detector and an apparatus with the
detector for controlling the process using microorganisms
Method and apparatus for the detection of toxic substances in
waste water feeding a biological treatment plant
3-Aminomethylene-2,4-pentanedione bis(thiosemicarbazone)
derivatives, and their production and use
Glass-surface microcarrier for anchorage-dependent cell
cultivation
Toxoplasmosis factor and production of same
Messenger RNA, production and use thereof
Fermentation process for production of carboxylic acids
Alcohol manufacturing process
Urokinase derivatives covalently bound to fibrinogen
Anti-Sm hybridoma
Method of producing biogas and compost
Flocculation of aqueous media with novel flocculating adjuvant
Antifreezing agent
Monoclonal antibodies specific for the unbound .beta. subunit of
human chorionic gonadotropin
Quaternized phthalocyanin derivatives
Production of immunogens by antigen conjugation to liposomes
Process for producing a hepatitis B infection preventing vaccine
Composition of matter and process
Method for determination of cholinesterase activity
Antibiotic, Spicamycin
Process for producing optically active aryloxypropionic acids and
derivatives thereof useful as herbicides
Dry culture media
Hydrogels capable of supporting cell growth
Recombinant DNA molecule
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786
787
4,565,789
4,566,469
788
789
790
791
4,566,985
4,567,024
4,567,136
4,567,137
792
4,567,138
793
4,567,139
794
795
796
797
798
4,567,140
4,567,141
4,567,142
4,567,143
4,567,144
799
800
801
802
803
804
805
4,567,145
4,567,146
4,567,147
4,567,149
4,568,457
4,568,488
4,568,542
806
807
808
809
4,568,544
4,568,545
4,568,636
4,568,637
810
811
4,568,638
4,568,640
812
4,568,641
813
814
815
4,568,643
4,568,644
4,568,645
816
817
818
4,568,646
4,568,675
4,568,739
819
820
4,569,647
4,569,788
821
4,569,790
822
823
824
825
826
827
4,569,840
4,569,841
4,569,845
4,569,907
4,569,908
4,569,909
Cell matrix receptor system and use in cancer diagnosis and
management
Process for dissimilatory denitrification of tobacco materials
Method of cleaning using liquid compositions comprising stabilized
mixtures of enzymes
Analytical element
Analytical element
Serum thrombin time in clinical medicine
Method for determining .gamma.-glutamyltransferase activity and
kits containing a novel substrate solution for use therein
Chromogen for measuring the formation of hydrogen peroxide
based on 1-substituted-aminoantipyrin compounds
Microbial polysaccharides, process for their preparation,
microorganisms suitable for this and use of the polysaccharides
Plasmid vectors including Tn904
Process for isomerizing glucose
Process for preparing 4'-deschlororebeccamycin
Method of producing long chain wax esters from ethanol
Continuous production of ethanol by use of respiration deficient
mutant yeast
Synthetic plasmid and bacteria containing it
Attenuated smallpox vaccine strain
Binding assay system and method of making and using same
Staged anaerobic reactor
Reverse immunoaffinity chromatography purification method
Vaccine compositions
Aqueous solution of a tissue plasminogen activator dissolved
therein at an increased concentration and a method
Thrombolytic agent
Tripeptide derivatives
Method of determining antibiotics in biological liquids
Method for screening microorganisms for the production of
glucose-2-oxidase
Method of inserting amino acid analogs into proteins
Process for producing optically active aryloxypropionic acids and
derivatives thereof
Continuous process for producing n-butanol employing anaerobic
fermentation
Fermentation method producing ethanol
Fungal pyranose-2-oxidase preparations
Preparation of antibiotic LL-D05139.beta. from cultures of
Glycomyces harbinensis, gen. nov., sp. nov.
Phenazine ACE inhibitor produced from streptomyces species
Method for degumming decorticated plant bast fiber
Apparatus for preparing and embedding tissue samples for
histological examination
Monoclonal antibodies against non small cell lung cancer
Process for recovering microbially produced interleukin-2 and
purified recombinant interleukin-2 compositions
Thymidine kinase-negative temperature resistant bovine
herpesvirus-1 mutant as a vaccine against infectious bovine
rhinotracheitis
Erwinia herbicola strain that inhibits pathogenic plant bacteria
Process for the batchwise preparation of vinegar
Thiopeptolide substrates for vertebrate collagenase
Multiclass hybrid interferons
Process for preparing uridine diphosphate-N-acetylgalactosamine
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828
829
830
831
832
833
834
835
836
4,569,910
4,569,911
4,569,912
4,569,913
4,569,914
4,569,915
4,569,916
4,570,379
4,571,332
837
4,571,381
838
4,571,382
839
840
4,571,383
4,571,384
841
842
843
844
4,571,385
4,571,386
4,571,387
4,572,219
845
846
4,572,798
4,572,894
847
848
849
850
4,572,895
4,572,896
4,572,897
4,572,898
851
4,572,899
852
4,573,195
853
4,574,083
854
4,574,116
855
856
857
858
859
860
861
4,574,117
4,575,459
4,575,484
4,575,485
4,575,486
4,575,487
4,575,488
862
863
864
865
4,575,489
4,575,490
4,575,500
4,575,551
866
867
868
869
870
871
4,576,718
4,576,793
4,576,796
4,576,817
4,576,912
4,576,913
Methods and reagents for pyranosone production
Method of making aspartic acid and purifying aspartase
Production of bilirubin oxidase
P. obtusus pyranose-2-oxidase preparation
Process for the sterile micropropagation of plant material
P. obtusus strain
Assay for tumor promoting agents
Lily processes
.sup.125 I and .sup.131 I labeled phospholipids
Hybrid cell lines producing monoclonal antibodies directed against
neurotransmitter degrading enzymes
Process for determining tumor-associated glycolinkage and
method for diagnosis of cancer
Reagent for measuring direct bilirubin by enzymatic method and
method for measurement thereof
Methane production
Genetic reassortment of rotaviruses for production of vaccines and
vaccine precursors
Feline infectious peritonitis vaccine
Biological-acid leach process
Process for improving tobacco
Method for promoting disulfide bond formation in recombinant
proteins
Process for synthesizing peptides or peptide derivatives
Process for preparing an antibiotic complex by culturing
actinomyces strain ATCC 39417
Monoclonal antibodies to herpes simplex virus type I polypeptides
Carrier for immobilizing enzymes
Thermophile isolate having thermostable hydrolytic activity
Aqueous solution for suspending and storing cells, especially
erthrocytes
System for the automatic observation and quantification of
phenomena capable of being detected by fluorescence
Isolates of pythium species which are antagonistic to Pythium
ultimum
Methods and cell lines for immortalization and monoclonal
antibody production by antigen-stimulated B-lymphocytes
Stabilization of phenylalanine ammonia-lyase in a bioreactor using
reducing agents
Toxoids of elastase of Pseudomonas aeruginosa origin
Binding assay for the detection of mycobacteria
Ultrasonic enhanced immuno-reactions
Process for differentiating the origin of particles in urine
Method for determination of transglucosidase
Interference free transaminase assay
Streptomyces albulus subsp. ochragerus subsp. nov. culture for
making peptide
One step method for sphering and fixing whole blood erythrocytes
Antifungal substances and process for their production
Acidic heteropolysaccharide AM-2
Use of water-absorbing, highly-filled polyurethane (urea)
compositions for biological treatment of waste-containing liquids
Analytical element
Centrifugal tissue processor
Enzymatic bandages and pads
Fluoroimmunoassaying
NAD(P)-Independent glycerol dehydrogenase, a process for the
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872
4,576,914
873
4,576,915
874
875
876
877
878
879
4,576,916
4,576,961
4,578,079
4,578,167
4,578,168
4,578,245
880
881
882
883
884
885
886
4,578,271
4,578,282
4,578,335
4,578,336
4,578,349
4,578,350
4,578,351
887
4,578,352
888
4,578,353
889
890
891
892
893
4,578,354
4,578,355
4,578,358
4,578,359
4,578,361
894
895
896
897
898
899
900
4,578,458
4,578,468
4,578,483
4,578,499
4,579,562
4,579,631
4,579,642
901
902
4,579,654
4,579,660
903
4,579,663
904
905
906
907
908
4,579,733
4,579,734
4,579,739
4,579,740
4,579,818
909
4,579,819
910
911
912
913
4,579,820
4,579,821
4,579,822
4,579,823
preparation thereof and the use thereof for the determination of
glycerol and triglycerides
Method for enhancing a fungus-lytic activity of .beta.-1,3-Dglucanase
Strains of Rhizobium phaseoli and preparation of cyclic
(1.fwdarw.2)-.beta. Electro-optical apparatus for microbial identification and
enumeration
Antibiotic heterocyclic oxygen compounds and use
Tetrapeptide
Cell fusion
Apparatus for fusing live cells with electric fields
Multilayer analytical element
Biologically active WS 6049 substances, a process for the
production thereof and their pharmaceutical compositions
Composition for diagnostic reagents
Interleukin 2 receptor
Producing nucleosides
Immunoassay for carcinoembryonic antigen (CEA)
Immunoassays employing protected labels
Production of chemical compounds with immoblized plant cells
Novel thermostable, aciduric alpha-amylase and method for its
production
Fermentation of glucose with recycle of non-fermented
components
Immobilization of catalytically active microorganisms in agar gel
fibers
Plasmid cloning vector pAS1
Collection of specimens and detection of occult blood therein
Occult-blood detection
Creatinine antibody
Mucoid exopolysaccharide vaccine against Pseudomonas
aeruginosa
Antibiotic LL-D42067.beta.
Gibberellin amine salts
Oxalic acid ester derivatives
Thermochemical beneficiation of low rank coals
Measurement of oxygen concentration
Electrochemical sensor having an immobilized enzyme membrane
Apparatus for the anaerobic fermentation of organic waste
material such as liquid manure
Method for treatment of biomass
Apparatus and method for optimizing separation of an unknown
sample by liquid chromatography
Hypocholesterolemically and/or hypotriglyceridemically active
products
Novel lactobacillus and uses therefor
Process for the manufacture of a naturally carbonated beverage
Fermentation method using a selected lactobacillus
Biosynthesis of unnatural cephalosporins
Method for production of ursodeoxycholic acid by means of
microbial transformation
Process for enzymatic replacement of the B-30 amino acid in
insulins
Control of DNA sequence transcription
Process for producing dihydroxyacetone kinase
Sterilization indicator
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914
915
4,579,827
4,580,682
916
4,581,028
917
918
919
920
921
4,581,223
4,581,231
4,581,237
4,581,331
4,581,332
922
923
4,581,333
4,581,334
924
925
4,581,335
4,581,336
926
927
4,581,337
4,581,338
928
929
4,581,360
4,581,847
930
4,582,514
931
932
4,582,699
4,582,704
933
934
935
4,582,787
4,582,788
4,582,789
936
4,582,790
937
4,582,791
938
4,582,792
939
940
941
4,582,793
4,582,794
4,582,795
942
4,582,796
943
4,582,797
944
945
946
947
4,582,798
4,582,799
4,582,800
4,582,801
948
4,582,802
949
4,582,803
950
4,582,804
Monoclonal antibodies to human gastrointestinal cancers and
hybridoma method of production of the monoclonal antibodies
Self-contained indicator device
Infection-resistant materials and method of making same through
use of sulfonamides
Individual leukocyte determination by means of differential
metachromatic dye sorption
Inactivation of viruses containing essential lipids
Cannery spoilage avoidance method
Method for the rapid detection of virus and viral antigens
Novel alkaline protease
Method of detecting and characterizing a nucleic acid or reactant
for the application of this method
Simultaneous detection of leukocyte phagocytic and killing ability
Process for producing a cloned luciferase-synthesizing
microorganism
Surface-modified electrodes
Polyether polyamines as linking agents for particle reagents useful
in immunoassays
Preparation of catalyst supports and materials produced thereby
Sparsomycin (S.sub.c -R.sub.s) derivative; pharmaceutical
composition having anti-tumor activity
Tryptophan overproducer mutants of cereal crops
Method for the removal of gaseous, volatile and/or liquid impurities
from waste gases
Assay of immunoglobulin A protease and the rapid diagnosis of
gonorrhea
Control of bean rust with Bacillus subtilis
Method of testing a patient for a predisposition to lung cancer,
certain other cancers, neurofibromatosis and certain other
hereditary disorders
HLA typing method and cDNA probes used therein
Process for labeling nucleic acids using psoralen derivatives
Monoclonal antibody to angiotension-converting enzyme and
methods of preparing and using same
Reducing non-specific background in immunofluorescence
techniques
Immunoassay method using two immobilized biologically active
substances
Anti-RNA polymerase I antibody test for the diagnosis of
rheumatological diseases
Method of determining polyamine content of biological fluids
Device for rapid diagnosis of dental caries
Erythromycin D and esters thereof by fermentation with Nocardia
sp. ATCC 39043
Monoclonal antibodies specific for human hematopoietic cell
surface glycoproteins
Preparation and use of enzyme-detergent extracted Streptococcus
equi vaccine
Process for recovering nonsecreted substances produced by cells
Novel vectors and method for controlling interferon expression
Process for producing glutathione
Stimulation of enzymatic ligation of DNA by high concentrations of
nonspecific polymers
Staged immobilized amyloglucosidase and immobilized glucose
isomerase in producing fructose from thinned starch
Microbiological synthesis of hydroxy-fatty acids and keto-fatty
acids
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951
952
953
954
955
4,582,805
4,582,806
4,582,807
4,582,811
4,582,860
956
4,582,875
957
4,582,878
958
959
960
4,583,952
4,584,141
4,584,194
961
962
4,584,197
4,584,268
963
4,584,269
964
965
966
4,584,270
4,584,271
4,584,272
967
968
969
970
971
972
973
974
4,584,273
4,584,274
4,584,275
4,584,277
4,584,400
4,585,488
4,585,585
4,585,598
975
976
977
4,585,623
4,585,653
4,585,735
978
979
980
981
982
983
4,585,736
4,585,737
4,585,738
4,585,739
4,585,740
4,585,741
984
4,585,742
985
986
987
988
4,585,754
4,586,604
4,587,018
4,587,044
989
990
991
992
993
994
4,587,100
4,587,102
4,587,212
4,587,213
4,587,214
4,587,215
Immobilization of biological matter via copolymers of
isocyanatoalkyl esters
Purification of phenylethanolamine N-methyltransferase
Cultivation medium for mycobacteria and use thereof
Method and diagnostic aid for detecting occult faecal blood
Oxirane resins for enzyme immobilization
Method of activating hydroxyl groups of a polymeric carrier using
2-fluoro-1-methylpyridinium toluene-4-sulfonate
High-rigidity ethylene-propylene copolymer and process for
producing same
Method for teaching multiplication and division with numbers 6
through 9
Process relating to triglyceride oils
Inactivated rabies vaccine for veterinary use
Process for preparation of fish and shellfish extracts having
pharmaceutical functions
Method and compositions for carcinoma diagnosis
Method for stabilizing the enzymatic activity of phenylalanine
ammonia lyase during L-phenylalanine production
Process for preparing optically-active 4-amino-3-hydroxybutyric
acid
Bacterial regeneration apparatus and process
Adenylate kinase and process for the production thereof
Method for the production of phenylalanine ammonia-lyase by
fermentation
Bacteriophage-resistant plant growth promoting rhizobacteria
Incubator
Fluorescent multiparameter particle analysis
Refining phenylalanine
Method for disinfecting contact lenses
Decapeptides produced from bioadhesive polyphenolic proteins
Phosphate esters of hydroxy-pyrene-sulfonic acids
Device for performing quantitative chemical and immunochemical
assays
Neuraminidase treated ancrod
Prolonged storage of red blood cells
Flow cytometric measurement of total DNA and incorporated
halodeoxyuridine
Preparation of oxygenated ambroxides
Immobilized enzyme systems
Plasmid for foreign gene expression in B. subtilis
Prolactin immunoassay using synthetic peptide
Method of assay for vitamin D metabolites
Monoclonal antibody with specificity to human small cell
carcinoma and use thereof
Stabilization of proteins and peptides by chemical binding with
chondroitin
Culture collection instrument and sealed swab holder therefor
Fibrin gel
Linkage of proteins to nucleic acids
Multilayer analytical element for the detection of hydrogen
peroxide
Multi-layer analysis element utilizing specific binding reaction
Immunoassay
Methods and means of determining microorganism population
Process for preparation of aspartylphenylalanine alkyl esters
Highly thermostable amyloglucosidase
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995
996
997
998
4,587,216
4,587,217
4,587,218
4,587,219
999
1000
1001
1002
4,587,220
4,587,333
4,588,561
4,588,579
1003
1004
1005
1006
4,588,584
4,588,585
4,588,586
4,588,588
1007
1008
1009
1010
4,588,595
4,588,680
4,588,681
4,588,682
1011
1012
4,588,683
4,588,684
1013
1014
1015
1016
1017
4,588,685
4,588,686
4,588,687
4,588,688
4,588,689
1018
4,588,690
1019
4,588,691
1020
1021
1022
4,588,692
4,588,693
4,588,694
1023
1024
1025
1026
1027
1028
1029
1030
1031
1032
1033
4,588,822
4,588,836
4,589,548
4,589,987
4,590,003
4,590,072
4,590,156
4,590,157
4,590,158
4,590,159
4,590,160
1034
1035
1036
1037
1038
4,590,161
4,590,162
4,590,163
4,590,164
4,590,168
Microbiological oxidation reactions using purified monooxygenase
enzyme components
Vicinal heterogeneous dihalogenated products and method
Novel bioconverting microorganisms
Device for measuring concentration including valve means
Ascorbate interference-resistant composition, device and method
for the determination of peroxidatively active substances
Cephalosporins and their production
Package for removing oxygen from a gaseous mixture
Process for the production of thin sections of biological tissue
Medium for the isolation of Pseudomonas cepacia biotype from
soil and the isolated biotype
Human recombinant cysteine depleted interferon-.beta. muteins
Method for disinfecting a contact lens
Antibiotic EM5487
Culture containing a viable cell mass of Bifidobacteria and lactic
acid bacteria
Assay for viruses
Process for producing adult T cell leukemia associated antigen
Binding nucleic acid to a support
Method of preparing 11.beta., 17.alpha., 20, 21-tetrahydroxy
steroids and corresponding 11.beta., 17.alpha., 21-trihydroxy-20oxo steroids
a-Factor and its processing signals
Process for the preparation of a new-type active substance
selectively inhibiting food intake
Enzymatic process for preparing glucuronides
Method for producing L-tryptophan by fermentation
Process for the production of muconic acid
Restriction endonuclease XcyI
Preparation of the enzyme .beta.-glucanase by fermentation of
fungi
Method for preparation of Fraction I protein and by-products
thereof
Antibiotic compounds, process for the preparation and
pharmaceutical compositions thereof, methods of treatment
therewith and Staphylococcus bacteria
Development of plant roots
Process for production of optically active oxazolidinone derivative
Physiologically active substances SS 12538, their preparation and
a novel microorganism producing same
Novel synthetic substrate and assay method using the same
Sputum collection apparatus
Separating animal cells from a liquid culture
Platelet related growth regulator
Live vaccine for bovine babesiosis and method of preparation
Agglutination assay and product for rubella antibody
Method for detecting antigens and antibodies
Microbial monitor
Enhancement of expression of protein synthesis in E. coli
Process for production of .beta.-glycosyl stevioside derivatives
Microbiologically produced L-phenylalanine-dehydrogenase,
process for its recovery and use
Transposable cloning vector
Broad host range DNA cloning system for gram-negative bacteria
Process for the preparation of a glucose-free hemoglobin standard
Protein immunoassaying and purification
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1039
4,591,456
1040
1041
4,591,504
4,591,505
1042
4,591,550
1043
4,591,551
1044
4,591,552
1045
1046
1047
4,591,553
4,591,554
4,591,555
1048
4,591,556
1049
4,591,557
1050
1051
4,591,558
4,591,559
1052
1053
1054
1055
4,591,560
4,591,561
4,591,562
4,591,563
1056
1057
1058
4,591,564
4,591,565
4,591,566
1059
1060
4,591,567
4,591,570
1061
1062
1063
4,591,572
4,592,728
4,592,760
1064
1065
1066
1067
4,592,868
4,592,994
4,592,995
4,592,996
1068
1069
1070
1071
1072
1073
1074
4,592,997
4,592,998
4,592,999
4,593,000
4,593,001
4,593,002
4,593,003
1075
4,593,004
1076
4,593,005
Process for obtaining homogeneous layers of native collagen, its
application in covering or encapsulating various supports and the
supports thus covered
Human leucocyte pepsin-like enzyme as a therapeutic agent for
treating allergic disorders and immune complex diseases
Process for inactivating hepatitis B virus
Device having photoresponsive electrode for determining analytes
including ligands and antibodies
Radioenzymatic method for assaying normetanephrine and
octopamine
Detection of hepatitis B surface antigen (or antibody to same) with
labeled synthetic peptide
Process and analytical agent for the determination of the activity of
glutamate-oxalacetate-transaminase
Rapid method for detecting microorganisms
Malate dehydrogenase method
Apparatus and associated methods for use in microbiological,
serological, immunological, clinical-chemical and similar laboratory
work
Process and materials for producing soluble biological mediators
from white blood cells
Novel substances having antitumor and immunostimulating
activity, process for preparing the same and antitumor agent
containing the same
Antibiotic X-14934A and a method for its preparation
Process for saccharification of starch using enzyme produced by
fungus belonging to genus Chalara
Process for the preparation of maltopentaose
Method for producing L-phenylalanine by fermentation
Process for the purification of dextran-sucrase
Transferase enzymes which modify the 3'-termini of ribonucleic
acid and methods
Method for thermal destabilization of microbial rennet
Biological indicator probe for steam sterilizing systems
Recombinant DNA screening system including fixed array
replicator and support
Matrix of antibody-coated spots for determination of antigens
Pigmentation associated, differentiation antigen of human
melanoma and autologous antibody
Periodontal lavage delivery system
Coal slurry
11-hydroxypregn-4-en-3-one-20-carbaldehyde and a method for
its production
Method for the determination of biochemical data
Reagent for streptococcal anti-esterase assay
Process for determining reduced form coenzymes
Process for the detection of the presence of an allergy and for the
specific detection of the allergen responsible for the allergy
Process for coupling biological substances by covalent bonds
Process for producing daunomycin
Method of producing guanosine
High temperature isomerization process
Viruses with recombinant surface proteins
Bacterial method and compositions for isoprenoid degradation
Process for the immobilization of cyclodextrine glycosyltransferase
enzyme
Strains of Aspergillus and use thereof to produce amylolytic
enzymes
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1077
1078
4,593,097
4,593,611
1079
1080
1081
1082
4,594,078
4,594,224
4,594,237
4,594,244
1083
1084
1085
4,594,245
4,594,248
4,594,318
1086
1087
1088
1089
1090
1091
1092
1093
1094
1095
1096
1097
1098
1099
4,594,319
4,594,320
4,594,321
4,594,322
4,594,323
4,594,324
4,594,325
4,594,327
4,594,466
4,594,810
4,594,884
4,595,418
4,595,439
4,595,505
1100
1101
1102
1103
1104
1105
1106
1107
1108
4,595,524
4,595,582
4,595,588
4,595,589
4,595,590
4,595,653
4,595,654
4,595,655
4,595,656
1109
4,595,657
1110
4,595,658
1111
4,595,659
1112
4,595,660
1113
1114
1115
1116
1117
1118
4,595,661
4,596,089
4,596,696
4,596,707
4,596,709
4,596,768
1119
1120
4,596,769
4,596,770
Phenazine carboxylic acid derivatives and a process for
production thereof
Vinification apparatus
Continuous digester of the production of biomethane for organic
substances
Analytical element
Method for testing chemical and biological substances
Antigenic materials
Augmenting factors for human antibody production and process
for peparing the same
CL-1577-B.sub.4 compound, its production and use
Isolation and localization of DNA segments
Protein kinase enzyme AUT-PK 500 and a radioimmunoassay for
detection of neoplasia
Process for producing 3-deoxyguanosine
Process for producing 3-deoxyguanosine
Glucose or maltose from starch
Hybrid DNA conferring osmotic tolerance
Microbiological process for oxidizing organic compounds
High fusion frequency fusible lymphoblastoid cell line
Assay method for whole blood samples
Recovery of alcohols
Inbred corn line
Diffusion measuring device
Production of powdery maltose
Process of forming a multiple profile reagent card
Method for suppressing algal growth in solar ponds
Two component stain composition for producing a Giemsa blood
stain effect
Dyestuff composition for histological examinations
Natural inhibitor that protects against viral infections
Fungistatic method
Method for preventing or treating pseudo-membranous colitis
Process for assaying cellular immunity
Method for detecting immune complexes in serum
Assay method and reagent therefor
Coupling agents and products produced therefrom
Process for preparing an inhibiting agent against proliferation of
animals malignant tumor cells
Method for facilitating externalization of proteins synthesized in
bacteria
Fermentation production of ascorbic acid from L-galactonic
substrate
Molecular cloning with bifunctional plasmid vectors in Bacillus
subtilis, mutants and substantially stably transformed mutants of
Bacillus subtilis, and methods for utilizing the transformed mutants
Immunoassays and kits for use therein which include low affinity
antibodies for reducing the hook effect
G-banding of plant chromosomes
Disposable sterilizer mechanical air removal test pack
Babesia parasite antigen useful in vaccine and diagnostic reagent
Novel immunostimulating glycoproteins
Antibodies for penicilloic acid their preparation and use
Monoclonal antibodies to peptidoglycan and methods of preparing
same
Assay of peroxidase enzyme activity
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1121
1122
1123
4,596,771
4,596,772
4,596,773
1124
1125
1126
4,596,774
4,596,775
4,596,776
1127
1128
1129
1130
1131
1132
4,596,777
4,596,778
4,596,779
4,596,822
4,597,762
4,597,940
1133
1134
1135
4,597,968
4,597,982
4,598,042
1136
1137
1138
4,598,043
4,598,044
4,598,045
1139
1140
1141
1142
1143
1144
1145
1146
1147
1148
4,598,046
4,598,047
4,598,048
4,598,049
4,598,050
4,598,051
4,598,089
4,598,145
4,598,146
4,599,176
1149
4,599,197
1150
4,599,226
1151
1152
4,599,303
4,599,304
1153
4,599,305
1154
4,599,306
1155
1156
4,599,307
4,599,308
1157
1158
4,599,309
4,599,310
1159
4,599,311
1160
4,599,312
1161
4,599,313
Monoclonal antibodies to vitamin B-6 and immunossay method
Reagent for assaying cholinesterase
Sterilization indicator
Method of preparing murine monoclonal antibodies against cellfree products of activated human T-lymphocytes
Microorganism and its use for the preparation of glutathione
Process for making starch hydrolyzates and high fructose syrups
Process for preparing (3S)-3-[[[2-(protected or unprotected
amino)-4-thiazolyl]acetyl]amino]-2-oxo-1-azetidinesulfonic acid
and 4-substituted derivatives thereof
Single cell protein from sulfur energy sources
Culture vessel with agitator
Heterocyclic inhibitors of serine proteases
Collagen preparation
Preservative treatment of wood
Antibiotic 13-384 complex from Micromonospora carbonacea var
africana
Method for processing flexible sheets
Immunoassay with an increasing cyclic detection system
Method for quantitatively assaying blood coagulation factor XII in
human plasma
Enhanced luminescent or luminometric assay
Triphasic mycoplasmatales detection method
Mutant strain of Escherichia coli and its use for the preparation of
glutathione
Phenylalanine ammonia lyase-producing microbial cells
Preparation of a maltogenic amylase enzyme
General purpose gene synthesizer
Culture plate for surfaces
Liposome conjugates and diagnostic methods therewith
Leucine derivatives
Albacarcins V and M
Compound, arugomycin
Process for the production of cell stimulating agents
Purification and activity assurance of precipitated heterologous
proteins
Wound dressing comprising silver sulfadiazine incorporated in
animal tissue and method of preparation
Nucleic acid hybridization assay employing probes crosslinkable to
target sequences
Method for monitoring activated cell subpopulations
Method and composition for detection of human chronic
myelogenous leukemia
Monoclonal antibodies which specifically bind to human immune
interferon
Method for elimination of selected cell populations in analytic
cytology
Protein from SV40 recombinants
Post cultivation treatment of yeast cells to facilitate product
recovery
Process for producing antitumor antibiotic compound
Glycolytic promotersfor regulated protein expression: protease
inhibitor
Method of producing endomycorrhizian fungi with arbuscules and
vesicles in vitro
Preservation of foods with non-lactose fermenting Streptococcus
lactis subspecies diacetilactis
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1162
1163
1164
1165
1166
1167
4,599,314
4,599,315
4,599,318
4,599,754
4,600,477
4,600,580
1168
1169
1170
1171
4,600,589
4,600,646
4,600,689
4,600,690
1172
1173
4,600,691
4,600,692
1174
1175
1176
1177
4,600,693
4,600,694
4,600,786
4,601,904
1178
1179
1180
1181
1182
1183
4,601,908
4,601,977
4,601,978
4,601,979
4,601,980
4,601,981
1184
4,601,982
1185
1186
4,601,983
4,601,984
1187
4,601,985
1188
1189
4,601,986
4,601,987
1190
1191
1192
4,602,007
4,603,013
4,603,105
1193
4,603,106
1194
1195
4,603,107
4,603,108
1196
1197
1198
1199
1200
1201
4,603,109
4,603,110
4,603,111
4,603,112
4,603,977
4,604,206
1202
1203
4,604,234
4,604,235
Multiple vessel specimen tray with lid for releasably adhering
vessel covers
Microdroplet test apparatus
Tissue protein PP.sub.19, a process for obtaining it, and its use
Combination wind screen and beach blanket apparatus
Method of processing fermented liquid
Novel enzyme derivatives
Meat tenderization with a proteolytic enzyme from Trichoderma
reesei
Metal oxide stabilized chromatography packings
Novel bilirubin oxidase, its production and use
Immunoassay
R-(Z)-4-amino-3-chloro-2-pentenedioic acid, novel antibacterial
agent
Immobilized cells for preparing phenylalanine
Thermostable alpha amylase having a low requirement for calcium
ions, derived from a bacillus microorganism
Apparatus for harvesting cells
Antibiotic obafluroin
Antibiotics xylocandin A and xylocandin B
Process for the preparation of penicillin-free mycelium masses
from penicillin production cultures formed by fermentation, and
their use as animal feeds and fertilizers
Method for measuring the activity of plasma factor XIII
Mammalian metallothionein promoter system
Process for preparing human insulin or B-30 esters thereof
Microbial expression of a gene for human growth hormone
Enzymatically active protein-enzyme complex membranes
Method for producing L-tryptophan by fermentation with a
brevibacterium flavum mutant
Coryneform bacteria carrying recombinant plasmids and their use
in the fermentative production of L-threonine and L-isoleucine
Process to produce antibiotics X-14873 A, G and H
Microorganism belonging to streptococcus thermophilus and a
composition containing said microorganism
Protein product of reduced nucleic acid content and low
allergenicity
Enzymatic production of optical isomers of 2-halopropionic acids
Salicylate culture media for inactivation of bacterial growth
inhibitors
Estrane derivatives
Efficient screening methods for low probability variants
Lipoprotein lipase suppression by endotoxin-induced mediator
(shock assay)
Reagent and process for the determination of the activity of the
enzyme gamma-glutamyl transferase
Method for identification of bacterial species
Method and apparatus for contacting reactants in chemical and
biological reactions
Starch hydrolyzates and preparation thereof
Preparation of biocatalysts in bead form
Modified vaccinia virus
Micromotility meter
Staged anaerobic reactor
Protein having cell growth stimulating action, composition thereof
and method for producing the same
Purification of monoclonal antibodies
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1204
1205
1206
1207
1208
1209
4,604,264
4,604,284
4,604,285
4,604,347
4,604,348
4,604,349
1210
1211
1212
4,604,350
4,604,351
4,604,352
1213
1214
1215
1216
1217
1218
1219
1220
1221
4,604,353
4,604,354
4,604,355
4,604,356
4,604,357
4,604,358
4,604,359
4,604,360
4,604,361
1222
1223
1224
1225
1226
4,604,364
4,604,377
4,605,558
4,605,559
4,605,614
1227
4,605,615
1228
4,605,616
1229
4,605,617
1230
1231
4,605,618
4,605,619
1232
1233
1234
4,605,620
4,605,621
4,605,622
1235
1236
1237
1238
1239
4,605,623
4,605,624
4,605,625
4,605,626
4,605,627
1240
1241
4,605,629
4,605,630
1242
4,606,351
1243
1244
1245
4,606,751
4,606,855
4,606,917
1246
1247
4,606,919
4,607,007
Test strips
Homogeneous immune interferon fragment
Protein C enzyme derivatives
Analytical element for dry analysis
Composition for use in immunoassays
Process for preparing uridine diphosphate-N-acetylgalactosamine
Screening test for beta-thalassemia trait and a diagnostic kit for its
individualization
Method for determining bacterial sensitivity to chemical agents
Co-culture production of thermostable enzymers and ethanol
Method for producing conjugated ursodeoxycholic acids by means
of microbial transformation
Immobilized glucose isomerase containing microbial cells
Maltogenic amylase enzyme, preparation and use thereof
Purification of flavin adenine dinucleotide synthetase
Antimicrobial disinfecting urinal block means and methods of use
Preparation of pasteurized human plasminogen
Microbial expression of a gene for human growth hormone
Culture transport apparatus
Reactor for producing gas by means of micro-organisms
Bioluminescent tracer composition and method of use in
immunoassays
Pharmaceutical compositions of microbially produced interleukin-2
Process for cell separation
Compound, FR-900447, production and use thereof
Method for measuring plasmin
L-glutamic acid oxidase (H.sub.2 O.sub.2 -generating), its
production and analytical method therefor
Determination of oxidized .alpha.-1-proteinase inhibitor in serum or
plasma
Process for culturing anaerobic bacteria and agents for preparing
culture atmosphere
Method for measuring anti-inflammatory properties of a
composition
Process for preparing fructose from starch
Process for fermenting carbohydrate- and phosphate-containing
liquid media
Clay-enzyme complexes and method for preparing same
Process for producing granular fixed enzymes or microorganisms
Method of altering growth and development and suppressing
contamination microorganisms in cell or tissue culture
Nocardia species capable of producing nargenicin C.sub.1
Process for producing S-adenosyl-L-homocysteine
Electrochemical system with rotating electrode/sparger assembly
Plasmid vehicle for cloning in Agrobacterium tumefaciens
Method of eluting reagent from reagent strips for chemical
analyses and reagent strip therefor
Large-liposome agglutination reagent and method
Optical indicator device for the remote measurement of physical
changes in a test subject
Biological method of controlling johnson grass and similar weeds
in agricultural crops
Monoclonal antibody to digoxin
Synergistic antiviral composition
Vaccine for the treatment of urinary tract infections containing
aluminum phosphate
Differentiation of natural killer cell subpopulations of cells
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1248
1249
4,607,008
4,607,009
1250
1251
1252
4,607,010
4,607,011
4,607,012
1253
1254
1255
1256
1257
1258
4,607,013
4,607,453
4,608,140
4,608,231
4,608,246
4,608,252
1259
4,608,253
1260
1261
1262
4,608,255
4,608,335
4,608,336
1263
1264
4,608,337
4,608,338
1265
1266
1267
4,608,339
4,608,340
4,608,341
1268
1269
4,608,342
4,608,343
1270
4,608,344
1271
1272
1273
1274
1275
4,608,397
4,609,460
4,609,548
4,609,549
4,609,550
1276
4,609,551
1277
4,609,622
1278
1279
4,609,623
4,609,624
1280
1281
1282
4,609,625
4,609,626
4,609,627
1283
1284
1285
1286
4,609,629
4,609,662
4,609,742
4,610,800
1287
4,610,815
Enzyme/immunofluorescent assay for anti-Epstein-Barr Virus
antibodies
Lewis blood group phenotype assay
Analytical process and means for measuring protease inhibitor
capacity of serum
Accumulation and isolation of N-acylphosphatidylserine
Antibiotic SB 22484
Biochemical process for optical resolution of cyclopentenolone
derivatives
Hybrid corn plants with improved standability
Electrodialysis apparatus and process
Self-contained reagent package device for an assay
Testing for a blood group immunological reaction
Chloramphenicol derivatives antigens and antibodies
Process for removing immune complex in blood by use of the
immobilized pepsin
Biocompatible method for in situ production of functional platelets
and product produced thereby lacking immunogenicity
Enzymatic urea assay
#3B theophylline immunoassay employing 9-theophylline reagents
Human hybridomas and the production of human monoclonal
antibodies by human hybridomas
Process for bioconversion-product recovery
Protoplast fusion method for high-frequency DNA transfection in
human cells
Immobilized aminoacylase enzyme
Living, fast-growing thyroid cell strain, FRTL-5
Method of growing a confluent layer of cells on a porous or semipermeable substrate and apparatus for practicing the method
Biologically pure culture of Streptomyces majorciensis Labeda
Method for the determination of species in solution with an optical
wave-guide
Filler-containing polyurethane (urea) compositions prepared from
prepolymers reacted with water in the presence of lignite or peat
Anaerobic purification equipment for waste water
Vaccines for pseudorabies disease and methods for use of same
Biologically active substance from Islets-Activating Protein
Bacillus cereus subspecies israelensis
Process of and material for stimulating growth of cartilage and
bony tissue at anatomical sites
Clinical determination and/or quantification of thyrotropin and a
variety of thyroid stimulatory or inhibitory factors performed in vitro
with an improved thyroid cell line, FRTL-5
Microbiologically produced D-2-hydroxy-4-methylpentanoic acid
dehydrogenase, process for its production and its use
Process for producing isopropyl alcohol from cellulosic substrates
Process for the production of modified proteins and product
thereof
Method for producing S-adenosyl-L-homocysteine hydrolase
Enzymatic conversion of certain sub-type A and AB erythrocytes
Process for the immunological determination of proteins in body
fluid which display a non-parallel inhibition curve to a reference
inhibitor
Method for using purine derivatives
Difficol, intermediate in antibiotic preparation
Method for unclogging drainage pipes
Process for producing and obtaining anaphylatoxin- and
cocytotaxin-containing leucotaxine preparations and of
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1288
1289
4,610,826
4,610,868
1290
1291
4,610,878
4,610,879
1292
1293
1294
1295
4,610,960
4,610,961
4,610,962
4,610,963
1296
1297
1298
1299
1300
1301
1302
4,610,964
4,610,965
4,612,169
4,612,247
4,612,281
4,612,282
4,612,283
1303
1304
1305
4,612,284
4,612,285
4,612,286
1306
1307
1308
1309
4,612,287
4,612,288
4,612,289
4,612,337
1310
4,612,725
1311
1312
1313
1314
1315
4,612,873
4,613,433
4,613,458
4,613,459
4,613,501
1316
1317
4,613,503
4,613,566
1318
4,613,567
1319
1320
4,613,568
4,613,569
1321
1322
1323
1324
1325
1326
1327
1328
1329
4,613,570
4,613,571
4,613,572
4,613,573
4,613,576
4,613,666
4,614,548
4,614,549
4,614,587
anaphylatoxin and cocytotaxin proteins in molecularly
homogeneous, biologically active form
Tetra-alkyl-2,2,5,5-cyclohexanone-4-ol-1 and sulphonylated
derivatives thereof
Lipid matrix carriers for use in drug delivery systems
Use of in vitro assay techniques to measure parameters related to
clinical applications of transfer factor therapy
Fibrinolytic enzyme from snake vernom
Monoclonal antibody to thrombospondin and method for assaying
for and isolating thrombospondin
Inhibition of reduction activities of leukocytes
Carriers for immobilization of physiologically active substances
Novel glutathione oxidase, its production and use
Novel microorganism and its use in a process for the preparation
of alpha amylase
Adsorption-desorption purification of glucose isomerase
Process for sterilization of enzyme contaminated by bacteria
Magnetic cellulose-derivative structures
Immunoassay for detecting immunoglobulins and test kit
Monoclonal antibodies reactive with human breast cancer
Method for purification of HBs antigen
Process for the enzymatic hydrolysis of non-gelatinized granular
starch material directly to glucose
Novel antitumor antibiotic awamycin and its production
Acid hydrolysis of biomass for alcohol production
Plasmids containing a gene coding for a thermostable pullulanase
and pullulanase-producing strains of Escherichia coli and Bacillus
subtilis containing the plasmids
Oxirane resins for enzyme immobilization
Method for analyzing liquid sample
Method for preparing infection-resistant materials
Method for acclimatizing and propagating plant tissue culture
shoots
Centrifuge chamber for cytodiagnostic investigation of epithelial
cells contained in a sample
Anaerobic fermentor
Regulatory substance of DNA synthesis
Lymphocyte growth factor
Inactivation of viruses in labile blood derivatives
Antibiotic A26201-1 and antibiotic A26201-2 produced by a novel
strain of actinoplanes
Hybridization assay and kit therefor
Immunoassay method for measuring immunological antigen in
fluid sample
Method for release and separation of parasites or parasite eggs
from meat
Stabilized composition of tetrazolium salts
Novel thermostable, aciduric alpha-amylase and method for its
production
Polyprenyl sulfone derivatives and process for producing the same
Yeast BAR1 gene plasmid
Automatic bacterial colony transfer apparatus
Human monoclonal antibodies to cancer cells
Neplanocin A derivatives
Chromatographic separation of dextrose from starch hydrolysate
Method for enzymatic cleaning and disinfecting contact lenses
Wastewater treatment method
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1330
1331
4,614,651
4,614,712
1332
1333
1334
1335
4,614,713
4,614,714
4,614,715
4,614,716
1336
1337
1338
4,614,717
4,614,718
4,614,719
1339
4,614,720
1340
1341
1342
1343
4,614,722
4,614,769
4,614,770
4,615,141
1344
4,615,877
1345
1346
1347
4,615,878
4,615,884
4,615,972
1348
1349
4,615,973
4,615,974
1350
1351
4,615,975
4,615,976
1352
1353
1354
1355
1356
1357
1358
1359
1360
1361
4,615,977
4,615,978
4,615,979
4,615,980
4,615,981
4,615,985
4,617,156
4,617,260
4,617,261
4,617,262
1362
1363
1364
1365
1366
4,617,263
4,617,264
4,617,265
4,617,266
4,617,267
1367
1368
1369
4,617,268
4,617,269
4,617,270
1370
1371
1372
4,617,271
4,617,272
4,617,273
1373
4,617,274
Interferon epsilon
Immunoassays with luciferase labeled ligands or receptors
Fluorogenic phosphate esters of hydroxy-pyrene-sulfonic acids for
fluorimetric determination of phosphatases
Use of novel L-glutamic acid oxidase
Predictive test for impending ovulation in mammals
Filter cell for electrochemically measuring enzyme concentrations
Process for cultivation of organisms wherein a uniform protein
from microorganisms is enzymatically degraded
Synthesis of sugar or sugar-alcohol fatty acid esters
Process for producing ribavirin
Hybrid cell line for producing monoclonal antibody to a human T
cell antigen, antibody, and methods
Method and apparatus for measuring the degree of reaction
between antigens and leukocyte cellular antibodies
NADH.sub.2 mimics as chiral pseudohydrogenases
NADHCN mimics as chiral pseudocyanotransferases
Process for encapsulating asexual plant embryos
Method of determining the oxidizing activity of a biological liquid,
and a corresponding reagent
Metachromatic dye sorption means for differential determination of
sub-populations of lymphocytes
Method and vaccine for treatment of demyelinating diseases
Stabilization of indicators for detecting enzyme activity
Genetically engineered organisms expressing surface proteins of
T. cruzi
Yeast expression vectors
Purified culture of Actinomadura verrucaspora subspecies
veractimyces
Synthesis and isolation of octopine and its analogues
Method for the cultivation of normal diploid cells and cultivation
medium used therefor
Bacterial growth medium and method of use
Diagnostic urine culture apparatus and method of using same
Plasmid pOA15
Process for obtaining cholesterol esterase from microorganisms
Immobilized protein on nylon for immunoassay
2-hydroxymuconic semialdehyde bisulfite adduct
RIA assay for HBcAg
Process for labeling nucleic acids and hybridization probes
Assaying for circulating immune complexes with labeled protein A
Method for quantitative determination of acetylputrescine in a
mixture
Pretreatment method and composition
Colony blot assay for enterotoxigenic bacteria
Production of Protein A
Plasmid pCG1 from Corynebacterium glutamicum
Process for the preparation of adenosine-5'-triphosphate by
fermentation
Process for the preparation of fructosyl disaccharides
Alcohol and distillers grain recovery process
Process for producing immobilized L-asparaginase preparations
for the therapy of leukemia
Enzyme drying process
Alpha-acetolactate decarboxylase enzyme and preparation thereof
Biochemical conversions by yeast fermentation at high cell
densities
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1374
1375
1376
1377
1378
4,617,378
4,617,383
4,618,475
4,618,486
4,618,492
1379
4,618,493
1380
1381
1382
1383
1384
4,618,494
4,618,576
4,618,577
4,618,578
4,618,579
1385
4,618,580
1386
1387
4,618,581
4,618,582
1388
1389
4,618,583
4,618,584
1390
4,618,585
1391
4,618,586
1392
4,618,588
1393
1394
1395
4,618,589
4,618,691
4,619,754
1396
1397
4,619,823
4,619,895
1398
1399
1400
1401
4,619,896
4,619,897
4,619,898
4,619,899
1402
1403
1404
4,619,903
4,620,817
4,620,819
1405
1406
4,620,928
4,620,930
1407
1408
4,620,948
4,620,978
1409
1410
1411
4,621,048
4,621,049
4,621,050
1412
1413
4,621,051
4,621,052
Purification of biologically active human immune interferon
Method for degumming and bleaching decorticated plant bast fiber
Reagent test device containing hydrophobic barriers
Monoclonal antibody formulation for diagnostic use
Acid-cleavable compound
Temperature sensitive strains of bovine viral diarrhoea virus,
preparation thereof and vaccines containing them
Human Immune Factors and processes for their production and
use
Diagnostic test for Streptococcus A
Human-human hybridoma, CLNH5
Expression of glycoprotein D of herpes simplex virus
Raw starch saccharification
Process for the production of L-tryptophan using sulfaguanidineresistant microorganisms
Clavine-producing strain, a process for the preparation thereof as
well as a microbiological process for producing clavine alkaloids
Process for producing Xanthomonas biopolymers
Method of preparing L-(+)-.beta.-hydroxyisobutyric acid by
fermentation
Ultrafiltration purification of glucose isomerase
Hybridoma cell lines producing monoclonal antibodies directed
against cervical cancer cells
Apparatus for administering a controlled dosage of a chemical
substance having an improved culture chamber
Reagent and merchandising kit for use in the diagnosis of syphilis
and preparation thereof
Immunoprecipitation assay of immunoglobulins using monoclonal
antibodies
Cyclotriphosphazatriene-derivatives
Chemically modified electrodes and their uses
Radioactive iodine labeled metaraminol and diagnostic agent
containing platelets labeled therewith
Lipoprotein marker for hypertriglyceridemia
Process for obtaining delta antigen of hepatitis D virus and use of
said antigen as a diagnostic agent
Enzyme immobilization in a fluorine resin membrane
Alcohol oxidase from Pichia-type yeasts
Method and device for performing microoperations on cells
Process for carrying out serological investigations according to the
principle of the complement fixation test, and test packages for
use in this process
Underground discharge for downspouts and sump pumps
Submarine working equipment
Process for reducing the hydrogen sulfide content in anaerobic
decomposition processes, especially in sludge digestion
processes
Process for rapidly determining biological toxicity of wastewater
Purification and activity assurance of precipitated heterologous
proteins
Hepatitis A virus purified and triply cloned
Reagents containing an anti-ligand bound to an anti-enzyme and
methods for employing said reagents in an immunoassy
Enzymatic high range glucose test
Process for the production of human colony-stimulating factor
Process for the production of human multiplication-stimulating
activity
Process for the production of human epidermal growth factor
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1414
4,621,053
1415
1416
1417
1418
1419
1420
1421
1422
1423
1424
1425
4,621,054
4,621,055
4,621,056
4,621,057
4,621,058
4,621,059
4,621,060
4,621,061
4,621,137
4,621,631
4,622,207
1426
4,622,222
1427
1428
4,622,291
4,622,292
1429
1430
4,622,293
4,622,294
1431
4,622,295
1432
1433
4,622,296
4,622,297
1434
1435
1436
1437
1438
1439
1440
1441
4,622,298
4,622,299
4,622,300
4,622,301
4,622,302
4,622,303
4,622,304
4,622,362
1442
1443
1444
1445
4,622,389
4,622,982
4,623,465
4,623,485
1446
4,623,618
1447
1448
1449
1450
1451
1452
1453
1454
4,623,619
4,623,620
4,623,621
4,623,622
4,623,623
4,623,624
4,623,625
4,623,626
1455
1456
1457
4,623,627
4,623,629
4,623,717
1458
4,624,835
Process for the production of human peptide hormones
Biologically active substance, process for preparing the substance
and immunoactive composition
Process for producing biologically active factors
Process for producing stable sulpho-adenosyl-L-methionine salts
N-acetylhexosamine oxidase and process for producing the same
Method of preparing cheese starter media
Apparatus for measuring velocity of enzyme reaction
Apparatus for taking samples from a fermenter
Plasmid p SG 2 and process for its preparation
Alpha-glycosyl ginsenosides
Process for the production of a bonded collagen fiber sheet
Reagent test device having sealed matrix boundaries
Process for the preparation of a lyophilized vaccine against duck
virus hepatitis
Method and device for quantitative end point determination in
immunofluorescence using microfluorophotometry
Assay and kit for determining interferon
Iodothyronine immunoassays employing HMS as TBP blocking
agent
Liposome immunoassay reagent and method
Modified oligosaccharides used as substrate for measuring
.alpha.-amylase activity
Process for measuring activity of dehydrogenase employing a
reaction stopper
Process and agent for testing the sensitivity of bacteria
Detection and quantitation of microorganisms, leukocytes and
squamous epithelial cells in urine
Production of high D.E. syrups
Hydrolysis of lactose in whey
2-Oxocarboxylic acid reductase and its preparation
Process for inducing membrane fusion under an electric field
Defoamers for yeast fermentation
Method of growing cheese starter microorganisms
Polyacrolein microspheres
Novel substrate for determining the activity of blood coagulation
factor Xa (Stuart-Prower factor)
Continuous method of denitrating tobacco extracts
Removal of combined organic substances from aqueous solutions
4- or 6-substituted aldosterones
Simultaneous quantitative immunoassay for different antigens or
antibodies
Method for the determination of liability in human individuals to
develop atherosclerosis
Enucleated granulocytes, their preparation and use
Immunoassay for peptide and protein oligomers
T-cell growth factor and method of making same
Process for producing L-lysine by fermentation
Isolation of pancreatin
Enzyme extraction and purification processes
L-glutamic acid oxidase and its production
Monoclonal antibody having specificity for the double-stranded
conformation of native DNA and diagnostic methods using same
Solid-phase immunoassay support and method of use thereof
Pasteurized therapeutically active protein compositions
Microcentrifugation tube for the concentration of samples for
electron microscopy
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1459
1460
4,624,850
4,624,915
1461
1462
4,624,916
4,624,917
1463
1464
4,624,918
4,624,919
1465
1466
4,624,920
4,624,921
1467
1468
1469
4,624,922
4,624,923
4,624,924
1470
4,624,925
1471
1472
1473
1474
1475
1476
1477
4,624,926
4,624,929
4,624,930
4,624,931
4,625,014
4,626,277
4,626,354
1478
1479
1480
1481
4,626,430
4,626,431
4,626,432
4,626,501
1482
4,626,502
1483
1484
1485
4,626,503
4,626,504
4,626,505
1486
4,626,506
1487
1488
1489
4,626,507
4,626,508
4,626,509
1490
1491
4,626,510
4,627,982
1492
4,627,983
1493
4,628,026
1494
1495
4,628,027
4,628,028
Live attenuated human rotavirus vaccine
Positive selection sorting of cells
Process and composition for the rapid quantitation of small levels
of creative kinase-MB isoenzyme
Process for the production of human T-cell growth factor
Purification process for hepatitis surface antigen and product
thereof
Enzymatic production of phospholipid-saccharide derivatives
Process for the preparation of dicarboxylic acid using
microorganism
Human lymphoblastold cell line and hybridomas derived therefrom
Plasmid, method for construction of the same, microorganism
carrying the plasmid and method for cultivation of the
microorganism
Metal-coated polyaldehyde microspheres
Novel collagenase "discolysin" and production method thereof
Hybrid cell line for producing monoclonal antibody to a human
early thymocyte antigens, antibody, and methods
Novel cloning vehicles for polypeptide expression in microbial
hosts
Sample collector and assay device and method for its use
Immunochemical process
Recognins and their chemoreciprocals
Cell-delivery agent
Plant growth regulator
Method for anaerobic treatment of high strength liquors
Processes for growth of modified Pasteurella haemolytica bacteria
and preparation of a vaccine therefrom
Storage of red blood cells
Storage of red blood cells
Labeled DNA
Method for exposing bacterial antigen in bacterial cells assay
using same
Antitumor agents LL-D49194.alpha..sub.1, LLD49194.beta..sub.1, LL-D49194.beta..sub.2, LLD49194.beta..sub.3, LL-D49194.gamma., LL-D49194.delta., LLD49194.epsilon., LL-D49194.xi., LL-D49194.eta., LLD49194.omega..sub.1, LL-D49194.omega..sub.2, and LLD49194.omega..sub.3
DNA transfer vector for gram-negative bacteria
Selectable markers for yeast transformation
Process and device for the determination of cells secreting cellular
contents
Hybridomas producing monoclonal antibodies specific for a human
cell surface glycoprotein
Method for extending the viability of virulent Bacillus popilliae
Culture media transfer assembly
Plasmidic vectors for expressing in bacillus subtilis and a method
of preparing them
Partially purified bone-inducing factor
Functional protein hydrolyzates, a process for their preparation,
use of these protein hydrolyzates as a food additive, and foods
containing these protein hydrolyzated
Method and apparatus for automated double fluorochromization
analysis in lymphocytotoxicity testing
Vitro diagnostic methods using monoclonal antibodies against
connective tissue proteins
Novel thermostable pullulanase enzyme and method for its
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1496
1497
1498
4,628,029
4,628,030
4,628,031
1499
1500
1501
4,628,032
4,628,033
4,628,035
1502
1503
4,628,116
4,629,567
1504
1505
1506
1507
4,629,686
4,629,687
4,629,688
4,629,689
1508
1509
4,629,690
4,629,691
1510
1511
1512
4,629,692
4,629,693
4,629,694
1513
1514
1515
1516
4,629,695
4,629,696
4,629,697
4,629,698
1517
4,629,699
1518
4,629,700
1519
1520
1521
1522
4,629,701
4,629,706
4,629,742
4,629,783
1523
1524
1525
1526
4,629,792
4,629,819
4,630,448
4,631,135
1527
1528
1529
1530
1531
1532
1533
1534
1535
1536
1537
1538
1539
4,631,174
4,631,254
4,631,255
4,631,256
4,631,257
4,631,258
4,631,259
4,632,758
4,632,759
4,632,808
4,632,830
4,632,901
4,632,902
production
Method for the conversion of a cellulosic substrate to glucose
using Microbispora bispora, strain Rutgers P&W
Process for the production of rhamnolipids
Thermostable starch converting enzymes
Monoclonal antibody specific for a mammary tumor cytoplasmic
antigen
Novel host strain for transformation of Yarrowia lipolytica
Immunoassay method
Vinyl bromide extraction of butyric acid and butanol from microbial
fermentation broth
Alpha-1-antiprotease purification
Apparatus for delivering a controlled dosage of a chemical
substance
Positive selection sorting of cells
Homogeneous specific binding assay method
Binding assay with amplified read-out and gas-phase detection
Homogeneous enzyme specific binding assay on non-porous
surface
Tricyclic antidepressant conjugates with antigens and enzymes
Immunoassay for nonenzymatically glucosylated proteins and
protein fragments an index of glycemia
Sensitivity in fluorescence assays in icteric samples
Detecting and distinguishing between plasminogen activators
Peptide derivatives and use thereof as substrates for quantitatively
assaying enzymes
Process for the selective production of reduced oxygen species
Test system and procedure for the determination of NAD (P) H
Plasma expander based on starch
Process for the preparation of oligosaccharide fractions by
degradation of heparin
Selective conversion of cyano compounds to amides and
carboxylic acids
Process for preparing optically active carboxylic acids and
antipode esters thereof
Method for determining allergic sensitivity
Hydrolysis of fats
Synthetic antigen for the detection of AIDS-related disease
Chromatographic separation of tropicamide O-.beta.-Dglucuronide diastereomers
Novel hybrid corn plant
Container for storing solid living tissue portions
Treating a medium
Multilayer chemical analysis member having an outer waterproof
layer
Carcinoembryonic antigen determination
Composition for assaying for nitrites
Fermentation process for BBM-928
Stable high copy number plasmids
Irradiation alcohol fermentation process
Transposon in cloning DNA
Anaerobic wastewater treatment system
Wastewater treatment method
Chemical manipulator
Oral vaccine for immunization against enteric disease
Method and apparatus for immunoassays
Method for detecting biological activity in a body fluid
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1540
4,632,903
1541
1542
1543
4,632,904
4,632,905
4,632,906
1544
1545
1546
1547
1548
4,632,909
4,632,981
4,634,417
4,634,422
4,634,586
1549
4,634,590
1550
1551
4,634,663
4,634,664
1552
1553
4,634,665
4,634,666
1554
4,634,667
1555
1556
1557
4,634,668
4,634,669
4,634,670
1558
1559
1560
1561
1562
1563
1564
1565
1566
1567
1568
4,634,671
4,634,672
4,634,673
4,634,674
4,634,675
4,634,676
4,634,677
4,634,678
4,635,790
4,635,791
4,636,383
1569
1570
1571
4,636,385
4,636,386
4,636,388
1572
4,636,390
1573
1574
1575
1576
4,636,463
4,636,464
4,636,465
4,636,466
1577
4,636,467
1578
1579
1580
4,636,468
4,636,469
4,636,470
1581
4,636,471
Enzyme modified soy protein for use as an egg white substitute
Immobilized enzyme composites having carriers derivatized with
an organotitanate
Microbial sulfhydryl oxidase
Biodesulfurization of carbonaceous materials
Monoclonal antibodies which block infectivity of malarial parasites
to mosquitoes
Human antithrombin III
Process for treatment of tumors and apparatus therefor
Percutaneous access device and method for implanting same
Reagent and method for radioimaging leukocytes
Cell membrane proteins, compositions containing them and
procedure for their preparation
Method and reagent for quantitative determination of Nacetylhexosamine
Process for the production of human mono-clonal antibodies
Processes for inserting DNA into eucaryotic cells and for
producing proteinaceous materials
Human-murine hybridoma fusion partner
Process for preparing a heteropolysaccharide,
heteropolysaccharide obtained thereby, its use, and strain NCIB
11883
4-methylcyclohexa-3,5-diene-1,2-diol-1-carboxylic acid produced
by Pseudomonas putida ATCC No. 39119
Process and device for the differentiation of particles in a medium
Process for the preparation of cellulase
Water-soluble cross-linked polymer of lysyl endopeptidase,
process for preparing same and use of same
Immobilization of cells in polyurethane hydrogel
Enzyme purification process
Plant regeneration from protoplasts
Agitator for a fermentation and tissue culturing vessel
Replica plating device
Plasmid capable of expressing human growth hormone
Plasmid cloning and expression vectors for use in microorganisms
Container package for staining a biological specimen
Container package for staining biological specimens
Interferon-cyclaradine combination
Vaccine, method for its preparation, and use thereof in vaccinating
humans against rotavirus infection
Mycological method for controlling italian thistle growth
Preparing protein for hydrolysis and product
Process for producing protein aliments and various by products
from cereals
Antibodies to human interleukin-2 induced by synthetic
polypeptides
Pyranose oxidase, method of making and method of use
Method and composition for determination of glycerol
Phenylalanine ammonia lyase-producing microbial cells
Mixed microbial fermentation of carbonaceous matter to road deicer
Lipolytic enzyme derived from a aspergillus microorganism having
an accelerating effect on cheese flavor development
Isolation of hepatitis A virus strain HM-175
Resolution of racemates of amino acids
Biochemical method for preparation of optically active carnitine
Enterobacter sp. Y-239-b
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1582
4,636,472
1583
1584
1585
1586
1587
1588
4,636,473
4,636,474
4,637,053
4,637,861
4,637,977
4,637,978
1589
1590
1591
1592
4,637,979
4,637,980
4,637,981
4,637,982
1593
4,637,983
1594
1595
1596
1597
4,637,984
4,637,988
4,638,028
4,639,373
1598
1599
1600
1601
1602
1603
4,639,419
4,639,420
4,639,421
4,639,422
4,639,423
4,639,425
1604
1605
1606
4,640,767
4,640,778
4,640,785
1607
1608
4,640,834
4,640,835
1609
1610
1611
4,640,893
4,640,894
4,640,895
1612
1613
1614
4,640,897
4,641,528
4,642,120
1615
1616
4,642,131
4,642,220
1617
1618
1619
4,642,284
4,642,285
4,642,286
1620
4,642,287
1621
1622
4,642,288
4,642,289
1623
1624
4,642,290
4,642,291
Disposable sterilization biological test pack
Membrane and static mixer-moderated bioreactor with anti-fouling
device
Toilet apparatus
Computer assisted biological assay system
Stabilized, lipid membrane-based device and method of analysis
Method of determining dTk isoenzyme activity and the use thereof
Assay for analysis of whole blood
Composition and test device for determining the presence of
leukocytes containing a zwitterion coupling agent
Externalization of products of bacteria
Antibiotic A-4696 factor G
Process for biological preparation of amides
Hybrid cell line for producing monoclonal antibody to human
cytotoxic and suppressor T cells, antibody, and methods
Monoclonal anti-ornithine decarboxylase antibody and method of
producing same
Fluorescent labels for immunoassay
Rubber polymerases and methods for their production and use
Stabilization of granulocytes
Immunological color change test involving two differently colored
reagent spots
Method for the immunoanalysis of cholesterol epoxides
Fluorescent gram stain
Cell culture filter apparatus and method
Apparatus for the production of biocatalyst beads
Heterogeneous immunoassay and reagent therefore
Hydrocarbon extraction agents and microbiological processes for
their production
Fibrin gel-containing filter
Separation of lymphocytes and monocytes from blood samples
Method of inactivating reproducible filterable pathogens in blood
products as well as a method of producing blood products
Plasminogen activator derivatives
Novel rhodamine derivatives as fluorogenic substrates for
proteinases
Production of isomaltulose using immobilized microorganisms
Biphasic media culture apparatus
Immunoanalysis of basophil-containing blood fraction for
diagnosing parasitoses and allergies
Specimen analysis instrument assembly
Repair of cartilage and bones
Production of disease suppressive compost and microorganism
culture for use therein
Apparatus for carrying out analysis
Method and system for detection of complement pathway
activation
Sandwich EIA for antigen
Composition and method for ethanol determination
Process for pretreating biomasses in advance of their enzymatic
treatment
Process for producing thermostable alpha-amylases by culturing
micro-organisms at elevated temperatures
Process for cell disruption
Process for preparing a compound for use in the production of Lcarnitine
Cell surface antigens of human astrocytoma
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1625
4,642,292
1626
1627
1628
1629
4,642,293
4,642,334
4,642,411
4,643,756
1630
1631
4,643,899
4,643,901
1632
4,643,967
1633
4,643,968
1634
1635
4,643,969
4,643,970
1636
4,643,971
1637
1638
1639
4,643,972
4,643,973
4,643,974
1640
4,643,975
1641
4,644,057
1642
1643
1644
1645
1646
4,645,541
4,645,666
4,645,669
4,645,672
4,645,737
1647
4,645,738
1648
4,645,739
1649
1650
1651
4,645,740
4,645,741
4,645,830
1652
1653
1654
4,645,842
4,647,408
4,647,430
1655
1656
4,647,529
4,647,531
1657
4,647,532
1658
1659
1660
1661
4,647,533
4,647,534
4,647,535
4,647,536
1662
1663
1664
4,647,537
4,647,538
4,647,539
Method for isolation of connective tissue biomatrix
Novel hybridoma cell line producing monoclonal antibodies against
laminin and a process for the production thereof
Hybrid DNA prepared binding composition
Tryptophan overproducer mutants of cereal crops
Bioherbicide for Florida beggarweed
Microorganism having characteristics of an Arthrobacter capable
of degrading peanut hull lignin
Yeast strains, method of production and use in baking
Antibody method for lowering risk of susceptibility to HLAassociated diseases in future human generations
Process for determining metabolism and growth of cells under
various conditions
Novel cloning vehicles for polypeptide expression in microbial
hosts
Production of HCG
Monoclonal antibodies to human bladder and ureter cancers and
method
Method and apparatus for multiphase contacting between gas,
solid and liquid phases
Gas generator/indicator unit
Device for identifying microorganisms
Novel cloning vectors for use in streptomyces, escherichia coli and
related organisms
Process for the cleavage of peptides and proteins at the methionyl
bond using cyanogen chloride
Method of producing level off DP microcrystallinecellulose and
glucose from lignocellulosic material
Vaccine for bluetongue disease employing platinum compounds
Culturing and emplacement of differentiated cells in vivo
Preparation of improved bread with gamma-glutamyl transferase
Enzyme/immunofluorescent assay for anti-treponemal antibodies
Method for differential diagnosis of T cell leukemias using
monoclonal antibodies
Process and reagent for the determination of Ncarbamoylsarcosine with the use of a new enzyme
Process for enzymatic replacement of the B-30 amino acid in
insulins
Modified lipase
Stable composition of interleukin-2 and albumin
Pyrrole compounds for detecting the presence of hydrolytic
analytes
Carbapenem-type antibiotics
Volume independent test device
Hybridization method of detecting nucleic acid sequences with
probe containing thionucleotide
Generalized cytometry instrument and methods of use
Method for determination of hydrogen peroxide by
chemiluminescence analysis
Method for screening bacteria and application thereof for field
control of Pythium spp. on small grain crops
Ethanol production by high performance bacterial fermentation
Human nonsecretory plasmacytoid cell line
Method of encapsulating biomaterial in bead polymers
Immobilization of microorganisms antagonistic to plant pathogenic
microorganisms
Thermostable beta-amylase
Method and apparatus for growing cells in vitro
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1665
4,647,540
1666
4,647,543
1667
4,647,554
1668
1669
1670
1671
4,647,655
4,647,657
4,647,668
4,647,693
1672
4,647,773
1673
1674
1675
1676
1677
1678
4,648,968
4,649,026
4,649,049
4,649,058
4,649,105
4,649,106
1679
1680
4,649,107
4,649,108
1681
4,649,109
1682
1683
4,649,110
4,649,111
1684
1685
4,649,112
4,649,113
1686
1687
4,649,114
4,649,115
1688
1689
1690
1691
1692
1693
1694
1695
1696
4,649,116
4,649,117
4,649,118
4,649,119
4,649,121
4,649,135
4,650,547
4,650,662
4,650,674
1697
1698
4,650,676
4,650,689
1699
1700
1701
4,650,750
4,650,751
4,650,752
1702
1703
1704
4,650,753
4,650,754
4,650,755
1705
4,650,756
Automatic observation system for microorganisms and the like
Process for analyses to be carried out on immobilized biological
tissue
Biologically active substances from fibrinogen their preparation
and compositions containing them
Method for splitting di-sulphide bonds and a compound obtained
thereby
Heteropolysaccharide - NW-01
Disopyramide phenyl derivatives and labeled conjugates
Antibiotics DO-248-A and B and process for preparing the same
Method of continuous production of retroviruses (HTLV-III) from
patients with AIDS and pre-AIDS
Floating cover tank with guides for vertical displacement of the
cover
Diagnostic strips
Rabies vaccine
Gluco-oligosaccharide mixture and a process for its manufacture
Method of measuring biological ligand
Distinguishing subsets of human cells
Phenylethanolamine N-methyltransferase based radioenzymatic
assay for norephinephrine
Alpha amylase assay
Methods for isolating mutant microorganisms from parental
populations
Polymeric substance, and method of separating and culturing
bacteria to provide polymeric substance useful in liquid clarification
and soil conditioning
Process for the preparation of 5'-ribonucleotides
Utilization of xylan and corn fiber for direct fermentation by
clostridium acetobutylicum
Alkaline peroxide treatment of nonwoody lignocellulosics
Oxygen permeable membrane in fermenter for oxygen enrichment
of broth
Monoclonal antibodies to skin cells
Magnetic means for withdrawing magnetic gel beads from an
assay fluid
Air lift bioreactor
Cell culturing apparatus with improved stirring and filter means
Cloning systems for corynebacterium
Viability test device
Mycotrienin-related compounds
Method and membrane applicable to implantable sensor
Portable blood typing apparatus and method
Synergistic cytotoxic composition
Antigens and monoclonal antibodies reactive against merozoites
of Eimeria spp.
Process for ethanol production from cellulosic materials
Method of chemical analysis employing molecular release tag
compounds
Protected binding assay avoiding non-specific protein interference
Method for determining the freshness of fish and mollusks
Novel substrates for use in measuring the concentration of
kallikrein in urine
Method of quantifying storage mold contamination
Immobilizing microbial cells with polyfunctional aziridines
Monoclonal antibodies to cell surface antigens of human renal
cancer
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1706
4,650,757
1707
1708
1709
4,650,758
4,650,759
4,650,760
1710
1711
1712
1713
1714
1715
1716
4,650,761
4,650,762
4,650,763
4,650,764
4,650,765
4,650,766
4,650,767
1717
1718
1719
4,650,771
4,650,856
4,651,759
1720
1721
1722
1723
1724
4,652,447
4,652,449
4,652,450
4,652,451
4,652,452
1725
4,652,517
1726
1727
1728
4,652,518
4,652,519
4,652,520
1729
1730
1731
1732
4,652,521
4,652,522
4,652,523
4,652,524
1733
1734
1735
4,652,525
4,652,526
4,652,527
1736
4,652,533
1737
1738
4,652,599
4,652,639
1739
1740
4,653,510
4,654,197
1741
1742
4,654,210
4,654,211
1743
1744
1745
4,654,215
4,654,216
4,654,298
1746
1747
4,654,299
4,654,300
Process of enzymatic conversion of polysaccharides
Stabilization of enzymes useful in the production of glucosone and
other enzymatic processes
Method of producing L-carnitine
Modified alkaline phosphatase
Method for stabilizing and selecting recombinant DNA containing
host cell
Isolation of carboxypeptidase B enzyme
Protease and process for production and use thereof
Helper cell
Biologically pure culture of Streptoverticillium stramineum sp. nov.
Culturing apparatus
Respirometer module with replaceable sample chamber
Immunogens, antibodies, labeled conjugates, and related
derivatives for lidocaine and analogs thereof
Process for producing gluten having high solubility
Start-up process for the thermophilic denitrification of tobacco
Methods and compositions using monoclonal antibody to human
helper T cells
Encapsulating biological active substances into erythrocytes
Bacterial FSH binding inhibitor
Controlling alcohol fermentations
Oxalic acid removal in beer production
Methods for the in vitro detection and identification of unknown
pathogens or genetic entities
Diagnosing chlamydia infections with Re-lipopolysaccharide
complexed to carrier or antibody thereto
Bifunctional chelating agents and process for their production
Comparative assay method and device
Method for the early diagnosis of bordetella diseases and kit
therefor
Continuous lymphocyte cell lines, their production and use
Method of preparing a new polyether antibiotic from streptomyces
Soluble stabilized enzymes
Recombinant bacterial plasmids containing the coding sequences
of insulin genes
Ethanol-producing mutants of Clostridium thermosaccharolyticum
Process for culturing methylophilus methylotrophus
Method of solid phase immunoassay incorporating a luminescent
label
Method of continuous production of retroviruses (HTLV-III) from
patients with AIDS and pre-AIDS using permissive cells
Manufacture and expression of structural genes
Apparatus for collecting and/or growing protected biological
cultures
Cuvette for sampling and analysis
Methods and compositions using complement fixing monoclonal
antibody to human T cells
New compound, FR-900451, production and use thereof
Method for automatically controlling feed rate of alcohol solution
as raw material in a process for producing vinegar
Bread antistaling method
Method for detection of peritoneal inflammation or infection
Procedure for the irreversible binding of proteins onto polystyrene
surfaces with retention of their biological activity, polystyrene
surfaces obtained by this procedure, and their use
Fluorescent microbead quenching assay
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1748
1749
1750
1751
4,654,301
4,654,302
4,654,303
4,654,304
1752
4,654,305
1753
1754
1755
1756
1757
1758
1759
1760
1761
4,654,306
4,654,307
4,654,308
4,654,310
4,654,312
4,654,334
4,655,794
4,655,814
4,655,835
1762
1763
1764
1765
1766
1767
1768
1769
1770
1771
1772
1773
1774
1775
4,655,880
4,655,918
4,655,924
4,655,926
4,656,025
4,656,035
4,656,036
4,656,037
4,656,047
4,656,127
4,656,128
4,656,129
4,656,130
4,656,131
1776
4,656,132
1777
1778
1779
1780
1781
1782
4,656,133
4,656,134
4,656,135
4,656,136
4,656,137
4,656,138
1783
1784
4,656,140
4,656,251
1785
1786
1787
1788
1789
4,656,252
4,656,253
4,656,255
4,656,288
4,657,658
1790
4,657,739
1791
1792
4,657,760
4,657,849
Process for detecting LDH.sub.k isozyme activity in human serum
for use as a diagnostic aid and for monitoring response to cancer
therapy
Process for the preparation of desulfatohirudins
Construction of novel mutant microorganisms
Composition for cell cultivation, production and use thereof
Multiphase reactor systems based on foams for simultaneous
growth and separation of products
Novel bacterium, Acetobacter altoacetigenes MH-24, useful for the
fermentation production of vinegar
Novel bacteria containing a plasmid having a tRNA code
Bioreactor
Instrumentless quantitative analysis system
Lysing agent for analysis of peripheral blood cells
Manganese-containing antibiotic agents
Liquid cleaner containing viable microorganisms
Waterways treatment composition and method
Process for evaluating the solubility of a colorant
Apparatus and method for sensing species, substances and
substrates using oxidase
Apparatus for cleaning waste water
Process for preparing biomass attached to a carrier
Process of treating effluent from a pulp or papermaking operation
Quantitative screening assay of tumor globulin from gastric juice
Method of separating blood platelets
Antibiotics Tejeramycin and production thereof
SPF-100 and process for the preparation thereof
Rapid method for cell block preparation
Method of detecting mutations in DNA and RNA
Modified alkaline phosphatase
Assay for a ligand by use of supported binder and sac lysing agent
Collagen coated cell growth plates
Method for producing interferons
Method of improving the yield of heterologous protein produced by
cultivating recombinant bacteria
Method for enzymatic synthesis of isotopically labeled
carbohydrates
Gene amplification in eukaryotic cells
Process for producing L-isoleucine by fermentation
Method for producing L-aspartic acid
Method of processing animal cartilage
Fermenter
Method for a measurement of alcohol concentration in acetic acid
fermenting broth
Rapid separation of Dirofilaria immitis immune complexes
Amidobiotin compounds useful in a avidin-biotin multiple layering
process
Monoclonal antibodies against alveolar surfactant protein
Protein recovery
Antibiotics, their production and use
Semiconductor devices
Integral element for biological reaction and process for the
preparation thereof
Methods and compositions using monoclonal antibody to human T
cells
Compositions and methods useful for uropathogenic bacterial
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1793
1794
1795
4,657,850
4,657,851
4,657,852
1796
1797
4,657,853
4,657,854
1798
4,657,855
1799
4,657,856
1800
4,657,857
1801
4,657,858
1802
1803
4,657,859
4,657,860
1804
4,657,861
1805
1806
1807
4,657,862
4,657,863
4,657,864
1808
4,657,865
1809
4,657,866
1810
1811
1812
1813
4,657,867
4,657,868
4,657,869
4,657,870
1814
4,657,873
1815
4,657,909
1816
1817
1818
1819
1820
1821
4,658,017
4,658,018
4,658,022
4,658,082
4,659,471
4,659,550
1822
4,659,567
1823
1824
1825
1826
1827
4,659,568
4,659,569
4,659,570
4,659,655
4,659,656
identification or diagnosis and inhibition of adherence of
uropathogenic bacteria to cells having a structural element similar
to that of the active principle of the invention
Serodiagnosis of heartworm infection
Breast cancer diagnostic blood test
Method for B cell typing of total human lymphocyte sample
Immunoassays utilizing covalent conjugates of polymerized
enzyme and antibody
Assay systems based on magnesium-responsive enzymes
Composition and test device for determining the presence of
leukocytes, esterase and protease in a test sample
Glutathione peroxidase, process for production thereof, method
and composition for the quantitative determination of lipid peroxide
Yeast of the genus kluyveromyces modified for the expression of
preprothaumatin or its various allelic and modified forms or their
maturation forms, and the proteins obtained by that expression
Cloning vectors comprising a restriction site bank and the
construction thereof
Process for the treatment of fermentation broth containing vitamin
B.sub.12 and other corrinoids and for the preparation of vitamin
B.sub.12 concentrates
Process for producing L-lysine by fermentation
S-tetrahydroprotoberberineoxidase, process for producing the
same and use thereof
Preparation of naturally-occurring C2-C5 alkyl esters of C4-C5
carboxylic acids by means of fermentation of C5-C6 amino acids
in the presence of C2-C5 alcohols
Stabilization of a mutant microorganism population
Method for stabilizing peroxidase solutions
Pullulanase-like enzyme, method for preparation thereof, and
method for saccharification of starch therewith
Serum-free, synthetic, completely chemically defined tissue culture
media
Multiwell tissue culture assembly with features for reduced media
evaporation
Apparatus for testing reactions
Self-contained device for carrying out specific binding assays
Incubator optical system for viewing sterilization indicator
Preactivated plastics surfaces for immobilizing organo-chemical
and biologic materials
Antimicrobial and antitumor phenazine carboxaldehydes and
derivatives
Method for the large scale purification of human fibroblast
interferon
Process for producing homogeneous colony stimulating factor
Binding of antibody reagents to denatured protein analytes
Method for producing intact plants containing foreign DNA
Method of controlling an anaerobic treatment process
Method and apparatus for measuring blood coagulation time
Molecules with antibody combining sites that bind to hydrolytic
transition states
Process for solubilization, purification and characterization of
protein from insoluble protein aggregates or complexes and
compositions of matter therefrom
Process for the production of virus vaccine
Preparation containing stabilized physiologically active substance
Method for isolating product-producing cells
Method of detecting mastitis in cows
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1828
1829
1830
1831
4,659,657
4,659,658
4,659,659
4,659,660
1832
1833
1834
1835
1836
1837
4,659,661
4,659,662
4,659,663
4,659,664
4,659,665
4,659,666
1838
4,659,667
1839
1840
1841
1842
1843
1844
1845
1846
4,659,668
4,659,669
4,659,670
4,659,671
4,659,672
4,659,673
4,659,697
4,659,855
1847
1848
1849
1850
1851
1852
4,660,639
4,661,235
4,661,347
4,661,348
4,661,349
4,661,350
1853
4,661,351
1854
1855
1856
4,661,352
4,661,353
4,661,356
1857
1858
1859
4,661,407
4,661,442
4,661,443
1860
1861
1862
4,661,444
4,661,445
4,661,446
1863
1864
1865
4,661,447
4,661,448
4,661,449
1866
1867
1868
1869
1870
1871
1872
4,661,450
4,661,451
4,661,452
4,661,453
4,661,454
4,661,455
4,661,456
Chromogenic and fluorogenic esters for photometric or fluorimetric
determination of phosphatases or sulphatases
Lectin-coated latex agglutination assay for Neisseria gonorrhoeae
Diagnostic method for diseases having an arthritic component
A47934 antibiotic and process for production thereof
Process for the preparation of fermentation broth for coenzyme
B.sub.12 and other corrinoid production
Batch fermentation process
Methods for isolating cell fusion products
Structures containing immobilized microbial cells
Enzyme membranes for electrodes
Pure alkaline phosphatase, its preparation and use
Process to recover crystalline enzymes and crystalline enzymes
produced thereby
Controlled regeneration of corn plants and breeding strategies
therewith
Microbial expression of human influenza hemagglutinin proteins
Biological desulfurization of coal
Enzymatic separation of racemic mixtures of hydroxy compounds
Colony replicating device
Replicator for cultures of microorganisms
Antianaemic composition and a process for producing the same
Aryl sulfonyl fluoride compounds
Removal of volatile contaminants from the vadose zone of
contaminated ground
Chemo-receptive lipid based membrane transducers
Cytotoxic compositions
Babesiosis antigen and method for preparation
Herpes simplex virus subunit vaccine
Dental vaccine for inhibiting periodontitis
Compositions containing biosynthetic pesticidal products and at
least one phosphate, processes for their preparation and their use
WS 7739 substances, their preparation and pharmaceutical
composition containing the same
CL-1577-B.sub.4 compound, its production and use
Production of vineger with bacteria on a support
Glass-surface microcarrier for anchorage-dependent cell
cultivation
Producing lipid-protein membranes for chemical detection
Assay for measuring gene expression
Homogeneous immunoassays employing double antibody
conjugates comprising anti-idiotype antibody
Competitive ELISA for the detection of HTLV-III antibodies
Monoclonal antibodies and method of immunizing therewith
Regulatory glycoprotein for immune response and the use there of
in the production of T-cell growth factor
Method for producing reduced-form coenzyme
Process and installation for the preparation of a sweet wort
Molecular cloning of RNA using RNA ligase and synthetic
oligonucleotides
Methods for immobilizing and translocating biological cells
Enzyme containing granulates useful as detergent additives
Production of tissue plasminogen activator factor
GAL1 yeast promoter linked to non galactokinase gene
Membrane cell culturing device
Method for cultivation of pseudomonas bacteria
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1873
1874
1875
1876
1877
4,661,457
4,661,458
4,661,586
4,662,900
4,663,043
1878
1879
1880
1881
4,663,162
4,663,163
4,663,277
4,663,278
1882
4,663,280
1883
1884
1885
1886
1887
1888
1889
1890
1891
1892
4,663,281
4,663,282
4,663,283
4,663,284
4,663,285
4,663,286
4,663,287
4,663,288
4,663,289
4,663,290
1893
4,663,291
1894
1895
4,663,292
4,663,293
1896
4,663,294
1897
1898
4,663,295
4,663,298
1899
4,663,306
1900
1901
1902
1903
1904
1905
4,664,097
4,664,803
4,664,805
4,664,912
4,664,913
4,664,919
1906
1907
4,665,016
4,665,018
1908
1909
4,665,019
4,665,020
1910
1911
1912
1913
1914
1915
4,665,021
4,665,022
4,665,023
4,665,024
4,665,025
4,665,026
1916
4,665,027
Method for cultivation of pseudomonas bacteria
Cell culture system
Monoclonal anti-idiotype antibodies
Method for biological treatment of waste gases
Method of treating peroxide-containing wastewater
Method of using Bacillus polymyxa 9A to protect plants against
verticillium wilt
Modified polysaccharide supports
Virus detection method and materials
Agglutination dependent enzyme channeling immunoassay
Expression and secretion vectors and method of constructing
vectors
Enhanced production of proteinaceous materials in eucaryotic
cells
Glycopeptide antibiotic CUC/CSV and process for its production
Method of altering double-stranded DNA
Process for enhanced fermentation of xylose to ethanol
Chimeric plasmids
Encapsulation of materials
Biologically active conjugates and their preparation and use
Process for purification of enzymes
Electrolyte solutions and in vitro use thereof
Production of reverse transcriptase
Method for solubilizing microbial protein obtained from Chlamydia
trachomatis
High-voltage biological macromolecule transfer and cell fusion
system
Device for testing air for microorganism content
DNA coding for a signal amino acid sequence and DNA containing
the same
Estrogen-progesterone control reagents and methods for making
same
Method for determining endotoxin concentrations
Pyridine-soluble extract-refined detoxified endotoxin composition
and use
Nuclear transplantation in the mammalian embryo by microsurgery
and cell fusion
Anaerobic treatment of wastewater
Analog enrichment decontamination process
Process for the large scale production of rabies vaccine
Method for treating plasma for transfusion
Method of producing lactic-acid fermented soy milk
Chromogenic compounds, a process for their preparation and their
use
Methods and test kit for diagnosing/monitoring cancer in humans
Method for measuring the plasma levels of an inhibitor of
(Na.sup.+ +K.sup. +
Flow cytometer measurement of binding assays
Diagnostic method of screening for immune deficiency in a
nephrotic patient by determination of SIRS in the urine
Bioluminescent assay reagent and method
Imidazole derivatives as redox indicators
Fluorescent gram stain
Process for the preparation of isoglucose
Enzymatic synthesis of (S)3-hydroxy-3-methylglutaryl coenzyme A
Immobilized cell reactor-separator with simultaneous product
separation and methods for design and use thereof
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1917
1918
1919
4,665,028
4,665,029
4,665,030
1920
4,665,031
1921
4,665,032
1922
1923
4,665,033
4,665,034
1924
4,665,035
1925
4,665,036
1926
1927
1928
1929
4,665,160
4,665,192
4,666,425
4,666,497
1930
1931
1932
1933
1934
4,666,605
4,666,606
4,666,697
4,666,699
4,666,713
1935
4,666,714
1936
1937
4,666,715
4,666,718
1938
1939
4,666,719
4,666,828
1940
1941
1942
1943
4,666,829
4,666,830
4,666,831
4,666,832
1944
1945
1946
4,666,833
4,666,834
4,666,835
1947
4,666,836
1948
1949
4,666,837
4,666,838
1950
1951
1952
1953
1954
1955
4,666,839
4,666,840
4,666,841
4,666,842
4,666,843
4,666,844
1956
4,666,845
Method for production of an immobilized enzyme preparation by
means of a crosslinking agent
Heat-resistant lipase
Process for regenerating corn
Clone of the sea kale (Crambe maritima L.), and process for
vegetative propagation thereof
Human T cell hybridomas which produce immunosuppressive
factors
Process and an apparatus for culturing microorganisms in a
nutrient solution
Device for performing qualitative enzyme immunoassays
Fermentation apparatus and systems for the cultivation of
microorganisms and other biological entities
Illuminating device for the optical, particularly image-analytical
evaluation of microbiological objects
Novel human growth hormone like protein HGH-V encoded in the
human genome
2-(2-furoyl)-4(5)-2(furanyl)-1H-imidazole
Device for perfusing an animal head
Bioactivating system for increased plant growth and yields
Methane fermentation process for treating evaporator condensate
from pulp making system
Method for eliminating grease and odors from sewage systems
Radioactive diagnostic agent
Stain-fixative composition for enteric parasites
Relating to hepatitis B vaccine
Nematophagous agent and a process for controlling the growth of
nematoda of the melodogynic species
Antibiotic AM-5344-A.sub.2 substance and process for the
production thereof
Preparation of low calorie beer
Admixture of a lactobacillus brevis and a saccharomyces dairensis
for preparing leavening barm
Test for Huntington's disease
Polypeptide marker for Alzheimer's disease and its use for
diagnosis
Assay employing sacs and sac lysing agent
Lipid-dependent diagnostic assays
Pyruvate oxidase
Process for the production of a diagnostic device for the detection
of increased dehydrogenase
Leukocyte adherence inhibition assay
2-vinylpenams and process
Novel cloning vehicles for polypeptide expression in microbial
hosts
DNA sequences, recombinant DNA molecules and processes for
producing the A and B subunits of cholera toxin and preparations
containing so-obtained subunit or subunits
Process for the production of L-aspartyl-L-phenylalanine esters
Methods and materials for obtaining microbial expression of
polypeptides including bovine prolactin
Process for the preparation of L-.alpha.-aminoacids
Production of picolinic acid and pyridine products
Novel aldehyde oxidase and process for producing same
Method for the purification of calf rennet
Process for regenerating cereals
Monoclonal antibodies to ovarian, cervical and uterine human
cancers and method of diagnosis
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1957
1958
4,666,846
4,666,847
1959
4,666,848
1960
1961
4,666,849
4,666,850
1962
1963
1964
1965
4,666,851
4,666,852
4,666,853
4,666,854
1966
4,666,855
1967
1968
1969
1970
4,666,864
4,666,866
4,666,937
4,667,016
1971
4,667,018
1972
1973
1974
4,667,504
4,668,476
4,668,503
1975
1976
1977
4,668,617
4,668,618
4,668,619
1978
4,668,620
1979
4,668,621
1980
4,668,622
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
4,668,623
4,668,624
4,668,625
4,668,626
4,668,627
4,668,628
4,668,629
4,668,630
4,668,631
4,668,632
1991
1992
4,668,633
4,668,639
1993
4,668,696
1994
1995
1996
1997
4,668,771
4,668,779
4,670,037
4,670,140
Novel cloning vectors containing selectable genetic markers for
use in streptomyces and related organisms
Recombinant DNA means and method
Polypeptide expression using a portable temperature sensitive
control cassette with a positive retroregulatory element
Lactic acid bacteria which do not decarboxylate malic acid and
fermentation therewith
Microbial pathogen detecting system and process
Specific mycoplasma membrane antigen and antibody and their
clinical applications
Photosynthetic bioconversion sulfur removal
Self-sufficient incubation assembly
Apparatus for producing compost
Rapid method for determining the isoelectric point for amphoteric
molecules
Gel composition for determining the fibrinogen content in plasma
by electroimmunodiffusion
Immunoassay for antigens employing supported binder
Avermectin bioconversion products
Erythropoietin purification
Process for the purification of proteins using acidic polysaccharide
gels
Flow through device for determination of the penetration rate of
chemicals across biological membranes in vitro
Automated polypeptide synthesis apparatus
Process for labeling amines with .sup.99m Tc
Apparatus and method for optically analyzing a plurality of analysis
items in a sample in a container
Nuclear isolation medium and procedure for separating cell nuclei
Multilayer homogeneous specific binding assay device
Reducing background interference activity in enzyme-label
immunoassays
Detecting blood clotting factors with immobilized fibrinogen and
labeled fibrinogen
Phenolsulphonphthaleinyl-.beta.-D-galactosides and diagnostic
agents containing them
Method of fluorometrically measuring the activity of fat-degrading
enzymes
Protein translation method
Process for preparing peptides
Method for the preparation of branched cyclodextrins
Novel antibiotic compound
Resolution of racemic mixtures of aliphatic acid esters
Human hybridomas, precursors and products
Stabilized enzymatic composition
Process for producing a restriction enzyme
Sparger and apparatus for and method of growing cells
Growth container and method for pathogenic and other laboratory
organisms
Biochemical detection method and kit for use therein
Novel averonectin fermentation product of a microorganism with
anthelmintic activity
Method for separating bovine lactoferrin from cow's milk and
purifying same
Gel-forming semisynthetic polygalactan metallic oxide complex
Fertilizer utilizing a chitin-producing fungus and method for its use
Fixed bed reactor column for anaerobic decomposition processes
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1998
1999
2000
4,670,255
4,670,259
4,670,260
2001
2002
4,670,379
4,670,380
2003
4,670,381
2004
2005
2006
4,670,382
4,670,383
4,670,384
2007
4,670,385
2008
2009
2010
2011
4,670,386
4,670,387
4,670,388
4,670,389
2012
4,670,390
2013
2014
4,670,391
4,670,392
2015
4,670,393
2016
4,670,394
2017
2018
2019
2020
2021
2022
2023
2024
4,670,395
4,670,396
4,670,397
4,670,398
4,670,399
4,670,406
4,671,909
4,671,937
2025
4,672,028
2026
4,672,029
2027
2028
2029
2030
2031
4,672,030
4,672,032
4,672,033
4,672,034
4,672,035
2032
2033
2034
4,672,036
4,672,037
4,672,038
2035
2036
4,672,039
4,672,040
2037
2038
4,672,044
4,672,108
Hair tonic composition
Compound FR-68504, production thereof and use thereof
Antibiotic for animal feeds
Polynucleotide hydridization assays employing catalyzed
luminescence
Assays utilizing labeled nucleic acid probes
Heterogeneous immunoassay utilizing horizontal separation in an
analytical element
Monoclonal antibody to Candida albicans cytoplasmic antigens
and methods of preparing same
Immune-chemical measurement process for haptens and proteins
Diagnostic reagent for swine trichinosis
Compositions and elements containing triarylmethane leuco dyes
and methods using same
Cancer tests using tumor antigen generated lymphokines and
compositions
Fermentative production of isomaltulose
Method of incorporating DNA into genome of drosophila
Process for producing N-acetylneuraminate lyase
Process for the immobilization of compounds comprising
nucleophilic groups
Sunflower regeneration through embryogenesis and
organogenesis
Sunflower regeneration through embryogenesis
DNA vectors encoding a novel human growth hormone-variant
protein
Isolation and culture of adrenal medullary endothelial cells
producing blood clotting factor VIII:C
Enantioselective hydrolysis of N-acylamino acid esters using a
combined enzyme system
Vertical culture system with removable culture unit
Fermentation apparatus
Plant tissue culture vessel and filter
Hybrid plasmid with marker
Tracers for use in assays
Method for making hollow porous microspheres
Multilayer analytical element
Compositions and method for simultaneous multiple array of
analytes using radioisotope chelate labels
Color-forming couplers and their use in the analytical
determination of hydrogen peroxide or other analytes
Test kit for the determination of activated thromboplastin time
(PTT) with increased sensitivity to heparin
Dental enamel production
Antibiotics X-14889 A,C and D
Oxidative enzyme-catalyzed crosslinking of beet pectins
Controlled regeneration of cotton plants from tissue culture
Pure cultures of Kibdelsporangium aridum Shearer gen. nov., sp.
nov. ATCC 39323 and mutants thereof
Method of culturing freeze-dried microorganisms
Optical readout for blood sample analysis
Apparatus for registering the presence of bacteria, particularly in
field conditions
Magnetic particles for use in separations
Murine monoclonal antibody combining site to human C3b
receptor (CR1)
Crystalline human leukocyte interferon
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2039
2040
2041
2042
2043
2044
2045
4,673,505
4,673,512
4,673,566
4,673,572
4,673,573
4,673,633
4,673,634
2046
2047
4,673,635
4,673,636
2048
2049
4,673,637
4,673,638
2050
2051
2052
2053
4,673,639
4,673,640
4,673,641
4,673,642
2054
4,673,643
2055
4,673,644
2056
2057
4,673,645
4,673,646
2058
2059
4,673,647
4,673,648
2060
2061
2062
2063
4,673,649
4,673,650
4,673,651
4,673,654
2064
4,673,733
2065
4,673,734
2066
2067
2068
2069
2070
2071
2072
2073
4,673,763
4,675,176
4,675,183
4,675,184
4,675,185
4,675,187
4,675,281
4,675,282
2074
2075
4,675,283
4,675,284
2076
2077
2078
2079
2080
2081
4,675,285
4,675,286
4,675,287
4,675,288
4,675,289
4,675,290
Wastewater treatment bacterial additive
Particle separation
Microencapsulation of living tissue and cells
Live purified Marek's disease vaccine
Novel fibrinolytic enzyme compounds
Method of determining cystic fibrosis ciliostatic factor
Purified antigen from non-A, non-B hepatitis causing factor
Triphenyl methane derivatives and method of quantitatively
measuring an oxidative substance
Medium for lysine decarboxylation test
Method for detecting bacteria in urine and for treating rheumatoid
arthritis, essential hypertension and other diseases associated
with bacteriuria
Method for detection and isolation of a microorganism
Dry form micronitrous acid streptococci extraction-agglutination
test
Regulated protein production using site-specific recombination
Co-aggregate purification of proteins
Plasmid P SVH 1 and its use
Process for the manufacture of iso-malto-oligosaccharide
monovalent haptens
Novel strains of agrobacterium and preparation of cyclic
(1.fwdarw.2)-.beta .
Process and microorganisms for producing mitomycin A by
fermentation
Production of 2-hydroxymuconic semialdehyde
Process to solubilize enzymes and an enzyme liquid product
produced thereby
Sunflower regeneration through organogenesis
Process and defined medium for growth of human epidermal
keratinocyte cells
Protein harvesting system
Multi-cell tray
Composition for determining peroxidase-like activity of hemoglobin
Treatment of biological and pharmaceutical products adsorbed on
a solid phase with virus and pyrogen inactivating agents
Porous mineral support coated with an aminated polysaccharide
polymer
Alpha-functionalized derivatives and labeled conjugates of
procainamide and NAPA
Moraxella bovis protease vaccine
Method for solubilization of interferon
Pharmaceutical composition containing interferon in stable state
Solution for stabilizing red blood cells during storage
BBM-1675, a new antibiotic complex
Quantification of hydroperoxides using prostaglandin H synthase
Assay for interferon epsilon
Detection and isolation of homologous, repeated and amplified
nucleic acid sequences
Process and apparatus for evaluating liver disease
Method for identification and isolation of DNA encoding a desired
protein
Fetal cell separation and testing
Monoclonal antibody directed to human ganglioside GD.sub.2
Method for the performance of a mutagenicity test
Method of measuring the number of eumycete cells
Assaying peptidase enzyme activity
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2082
2083
2084
2085
4,675,291
4,675,292
4,675,293
4,675,294
2086
2087
2088
2089
2090
2091
4,675,295
4,675,296
4,675,297
4,675,298
4,675,299
4,675,383
2092
2093
2094
2095
2096
2097
2098
2099
2100
4,675,386
4,675,387
4,676,951
4,676,956
4,676,974
4,676,980
4,676,981
4,676,986
4,676,987
2101
4,677,054
2102
4,677,055
2103
4,677,056
2104
4,677,057
2105
2106
2107
2108
2109
2110
2111
4,677,058
4,677,059
4,677,060
4,677,061
4,677,062
4,677,063
4,677,064
2112
2113
4,677,065
4,677,066
2114
2115
2116
4,677,067
4,677,068
4,677,069
2117
2118
2119
4,677,070
4,677,071
4,677,072
2120
2121
2122
4,677,073
4,677,080
4,677,194
2123
4,677,196
2124
2125
4,678,553
4,678,582
Human cultured cell line
Stabilization of glucose isomerase
Preparation of maltose and maltitol syrups
Process for production of methane by anerobic fermentation
Process for producing subculturable lymphokine-producing human
T cell hybridomas
Process for the extraction of .beta.-amylase from barley grains
Genes encoding bovine prolactin
Petri dish
Self-contained reagent package device and an assay using same
Purification of T-cell growth factor
Monoclonal antibody methods and compositions specific for single
antigens in antigen aggregates
Method for extracting protein with organic acid
Automatic specimen analyzing system
Apparatus for photosynthesis
Breath test for pancreatic exocrine function
Target specific cross-linked heteroantibodies
Monoclonal antibodies against GnRH
Schwanniomyces castellii strains and brewing process
Production of fermented whey containing calcium propionate
Method for simple analysis of relative nucleic acid levels in
multiple small samples by cytoplasmic dot hybridization
Immunological detection of bacterial pathogens with antibodycontaining magnetic gel
Monoclonal antibody subsetting human helper and killer T-cells
and method
Diagnostic assay for the presence of apolipoproteins associated
with plasma high density lipoproteins
Detecting malignant cells with monoclonal antibodies specific to
type IV collagenase enzyme
Process and reagent for the enzymatic determination of sulphite
Process for determining the pH value in the interior of a cell
T-cell lymphocyte subset monitoring of immunologic disease
Process for producing bilirubin oxidase
Human tumor necrosis factor
Human tumor necrosis factor
Production of improved protein isolate derived from seeds of a
grain legume
Method for promoting fusion of plant protoplast
Magnetotactic bacteria in clinical assay, immunoassay, and cell
separation procedures and the like
Process for obtaining cholesterol esterase
Clam derived proteinases
Pseudomonas aeruginosa exotoxin A antibodies, their preparation
and use
Antibiotic agents from S. coeruleorubidus, rubidus
Rhodotorula having desaturase enzymes
Process for preparing a stabilized Saccharomyces cerevisiae cell
culture
Rapid particle agglutination test for enterotoxigenic bacteria
Isolation of an endotoxin inactivator from human plasma
Purification and activation of proteins from insoluble inclusion
bodies
Renaturing reversibly denatured polypeptides and proteins by
electrodialysis of solutions thereof in denaturants
Treatment system for landfill leachate
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2126
4,678,746
2127
4,678,747
2128
4,678,748
2129
2130
2131
2132
2133
2134
2135
4,678,749
4,678,750
4,678,751
4,678,752
4,678,753
4,678,757
4,678,894
2136
2137
2138
4,680,174
4,680,176
4,680,180
2139
4,680,258
2140
2141
2142
2143
4,680,259
4,680,260
4,680,261
4,680,262
2144
2145
2146
4,680,263
4,680,264
4,680,265
2147
2148
4,680,266
4,680,267
2149
2150
2151
2152
2153
4,680,268
4,680,274
4,680,338
4,681,063
4,681,760
2154
2155
2156
4,681,762
4,681,782
4,681,839
2157
2158
4,681,840
4,681,841
2159
2160
2161
4,681,842
4,681,843
4,681,844
2162
4,681,845
2163
2164
2165
2166
4,681,846
4,681,847
4,681,848
4,681,849
Monoclonal antibodies to epizootic hemorrhagic disease virus
antigen
Monoclonal antibodies for detection of an H (O) blood group
antigen
Process for the production of immunobiological preparations
applicable in the diagnosis, prevention and/or treatment of
Candida guilliermondii infections
Ligands for affinity chromatographic purification of aldose
reductase
Method and compositions for use in the treatment of fireblight
Hybrid human leukocyte interferons
Automatic random access analyzer
Blood-culture flask with integrated subculture
Device and method for whole blood separation and analysis
Sample identification system
Induction of immune response by immunization with encapsulated
antigen-producing cells
Deletion mutant of a herpesvirus and vaccine containing said virus
Low alcohol beer prepared with hydrogenated starch hydrolyzate
Process for sex determination in man by use of monoclonal
antibodies to the H-Y antigen
Analytical element and method for colorimetric determination of
total cholesterol
Method for producing human leukocyte interferon alpha-2
Process for producing interferon
Periplasmic protein recovery
Continuous alcohol manufacturing process using immobilized
microorganism
Class II mobilizable gram-negative plasmid
Method of selecting recombinant DNA-containing streptomyces
Cell culture chamber with means for automatic replenishment of
nutrient
Fermentor control system
Implantable gas-containing biosensor and method for measuring
an analyte such as glucose
Particles for inhibiting non-specific immunoreaction
Bifunctional linker
High speed automated injection system for avian embryos
Method of conferring immunotolerance to a specific antigen
Genetically attenuated bacterial vaccines with multiple mutations
of the same phenotype
Article for determining the presence of immune complexes
Systems to preserve living tissue
Deoxyribonucleic acid molecules useful as probes for detecting
oncogenes incorporated into chromosomal DNA
Enzymatic assay method
Process and reagent for the differentiated determination of
isoenzymes of alkaline phosphatase
Immobilization of cells and enzymes
Process for producing an Interleukin-1 preparation
Increased glucose levels in starch saccharification using
immobilized amyloglucosidase
Process for the preparation of difficidin and derivative
antibacterials
Novel lysozyme-sensitive microorganism
Novel peptide and use thereof
Sunflower induction, maintenance and regeneration media,
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2167
4,681,850
2168
2169
2170
2171
2172
2173
2174
2175
4,681,851
4,681,852
4,681,853
4,681,930
4,681,931
4,682,654
4,682,890
4,682,891
2176
2177
4,683,062
4,683,135
2178
4,683,136
2179
4,683,137
2180
4,683,194
2181
4,683,195
2182
2183
4,683,196
4,683,197
2184
2185
4,683,198
4,683,199
2186
4,683,200
2187
2188
4,683,201
4,683,202
2189
2190
2191
4,683,203
4,683,204
4,683,205
2192
2193
2194
2195
2196
2197
2198
2199
4,683,206
4,683,207
4,683,209
4,683,213
4,683,221
4,683,230
4,683,293
4,683,295
2200
2201
2202
4,683,814
4,684,468
4,684,469
2203
4,684,609
2204
4,684,610
2205
4,684,611
methods of use and plants regenerated therefrom
Phenylalanine ammonia lyase-producing microbial cells
Biologically active composition for purifying waste water and
outgoing air
Novel microorganism and method
Perfusion slit chamber for filter-bound sample analyses
Immune interferon and a method for its extraction and purification
Process for the isolation and purification of alpha-interferons
Enzymatically-treated guar gums
Microsample holder and carrier therefor
Microcircle system
Method of circulation of a liquid phase through a solid phase
particularly for biocatalytical reactions and a device for realization
thereof
DSCG binding protein and process for preparing same
Proteinaceous antigens with conformation-independent and
conformation-dependent determinants
Temperature sensitive reassortant viruses and a vaccine against
equine influenza
Method for detection of polymorphic restriction sites and nucleic
acid sequences
Process for amplifying, detecting, and/or-cloning nucleic acid
sequences
Method and materials for the identification of lipopolysaccharide
producing microorganisms
Detection method for occult blood
Novel maltose dehydrogenase, process for its production, and
analytical method using the same
Interleukin-2 dependent cytotoxic T-cell clones
Monoclonal antibody to human cancer antigen and method for
producing same
Antibiotic A80190-producing Actinomadura oligospora and
process
Process for amplifying nucleic acid sequences
Immobilized enzymes, processes for preparing same, and use
thereof
Process for producing antibiotic A80190
Method for transforming microorganisms
Recombinant DNA cloning vectors containing selectable genetic
markers for use in Streptomyces and related organisms
Culture monitoring system
Viability test device
Method for predicting the fertility of male mammals
Lymphocyte-activating polypeptides
BMY-28121, a new antitumor antibiotic
Purification of pichia produced lipophilic proteins
Method for the preparation of anti-receptor antibodies
Apparatus and processes for compressing and/or biodigesting
material
Process and installation for anaerobic digestion
Two component biocidal process
Method and substance for the enhanced labelling of cellular
material
Process for converting 1,2-saturated steroids to 1,2-dehydro
steroids
Process for the in-vitro transformation of plant protoplasts with
plasmid DNA
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2206
4,684,612
2207
4,684,613
2208
4,684,614
2209
4,686,098
2210
4,686,179
2211
2212
2213
2214
2215
4,686,180
4,686,181
4,686,182
4,686,183
4,686,184
2216
2217
2218
2219
2220
2221
2222
4,686,185
4,686,186
4,686,187
4,686,188
4,686,189
4,686,190
4,686,191
2223
2224
2225
4,686,243
4,686,284
4,686,299
2226
2227
2228
4,686,307
4,686,308
4,687,489
2229
2230
2231
2232
2233
2234
2235
2236
2237
4,687,529
4,687,606
4,687,638
4,687,645
4,687,664
4,687,666
4,687,668
4,687,732
4,687,733
2238
2239
2240
2241
4,687,734
4,687,735
4,687,736
4,687,737
2242
4,687,738
2243
2244
4,687,739
4,687,740
2245
2246
4,687,741
4,687,742
Process for regenerating soybeans
Device for carrying out withdrawals of samples from semi-solid
media
Mixing or pumping apparatus for the treatment of flowable thin or
highly viscous media
Encapsulated mouse cells transformed with avian retrovirusbovine growth hormone DNA, and a method of administering BGH
in vivo
4- or 6-substituted aldosterones, their production and use in
immunoassay
Onco-fetal specific monoclonal antibodies, methods of preparation
and use
Specific binding assay employing anti-G6PDH as label
Method and kit for detecting antibiotics in a liquid sample
Process for the manufacture of p-menth-8-ene-1,2-diol
Gene transfer vector
Microorganism of new species of genus Streptomyces and use
thereof for production of chitinase
Recombinant vector and eukaryotic host transformed thereby
Process for preparing pectin from plant tissues
Producing anaerobic conditions
Apparatus for bioconversion of vegetal raw material
Device useful for growing and/or testing biological materials
Recombinant plasmid containing human interferon-beta gene
Copolymer, a process for its preparation and its use as enzyme
supports
Production of monomeric human .gamma.-interferon
Aerocavin antibiotics
Preparation of naturally-occurring C.sub.2 -C.sub.5 alkyl esters of
C.sub.4 -C.sub.5 carboxylic acids by means of fermentation of
C.sub.5 -C.sub.6 amino acids in the presence of C.sub.2 -C.sub.5
alcohols
Novel physiologically active substance MH435
Stabilizer for biological staining solutions
Method of making a reagent test device containing hydrophobic
barriers
Metalloid precursor powder and method of making same
Device for detecting and quantifying agglutinates
Composting unit
Method of inactivating reproducible pathogens
Vaccine for Leishmaniasis
Continuous microbiological production of acetic acid and vinegar
Visualization polymers and their application to diagnostic medicine
Early cancer detection method
Immunoassay for the detection of human colon cancer using a
polyclonal antibody derived from a capillary culture of tumor cells
Enzymatic poly-reactant channeling binding assay
Detection of biological substances by specific labelling techniques
Mammalian suppressor genes
Method for the production of HA fraction containing protective
antigens of Bordetella pertussis and pertussis vaccine
Method for treating aqueous solution of soybean protein with
enzymes
Decapeptides produced from bioadhesive polyphenolic proteins
Novel enzymes which catalyze the degradation and modification of
lignin
Xylose isomerase (glucose isomerase) from Streptomyces
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2247
2248
4,687,743
4,687,744
2249
2250
4,687,745
4,687,746
2251
4,687,747
2252
2253
4,687,748
4,687,764
2254
4,687,807
2255
2256
2257
2258
4,688,387
4,689,160
4,689,221
4,689,225
2259
2260
2261
2262
2263
2264
4,689,226
4,689,293
4,689,294
4,689,295
4,689,296
4,689,297
2265
2266
2267
2268
2269
2270
2271
2272
2273
4,689,298
4,689,299
4,689,300
4,689,301
4,689,302
4,689,303
4,689,304
4,689,305
4,689,306
2274
2275
4,689,309
4,689,311
2276
2277
2278
2279
2280
2281
4,689,401
4,689,406
4,690,773
4,690,801
4,690,815
4,690,826
2282
4,690,890
2283
4,690,891
2284
4,690,892
2285
4,690,893
2286
2287
4,690,894
4,690,895
murinus cluster
Sunflower regeneration media, method of use and plants
regenerated thereon
Artificial culture of the sexual stage of lagenidium giganteum
Use of rLDM.TM. 1-6 and other ligninolytic enzymes in the
treatment of mechanical pulps
Microorganism culture-transfer device
Phenanthridinium ester as a labelling compound in luminometric
immunoassay
Magnetic carbohydrate particles as carriers for affinity separation
purposes
Hypotriglyceridemically active polysaccharides
Use of amidase for reducing the acrylamide content of water-in-oil
emulsions containing acrylamide polymers
Method for preservation and storage of viable biological materials
at cryogenic temperatures
Acid stable heteropolysaccharide s-421
Oral composition containing antibodies to Bacteroides gingivalis
Vaccine for cytomegalovirus
Process for the production of a bacterial preparation for the
prophylaxis of intestinal disturbances in poultry
Microencapsulation of living tissue and cells
Enhancement of hybridization of nucleic acids by anionic polymers
Test for Salmonella
Method of preparing novel thermostable transglucosidase
Dust free particulate enzyme formulation
Mallory body specific monoclonal antibody and process for
producing same
Human monoclonal antibodies against bacterial toxins
Antibiotic producing Streptomyces thiolactonus
Transparent polyurethane foam wall
Spiral designed reactor
Controlled circulation incubator
Air/liquid detection device for blood sample analysis
Solid-state photometer circuit
Device for sterile sampling from a fermenter
Test device, method of manufacturing same and method of
determining a component in a sample
Screening antibodies for capacity to deliver toxin to target cells
Method of recovering microbially produced recombinant ricin toxin
a chain
Enhancement of microbial expression of polypeptides
Microbial enzymatic contact lens cleaner and methods of use
Device for performing enzyme immunoassays
Method for testing skin for presence of moisturizer
Bacterial enzyme used as cheese ripening aid
Process for simultaneously detecting multiple antigens using dual
sandwich immunometric assay
Method and the microorganism and enzyme used therein for
degrading the xanthan molecule
Process for the recycle of phase-forming liquids of multi-phase
aqueous systems
Hybridoma cell lines producing monoclonal antibodies which
specifically bind to mouse interleukin-2
Treatment of microorganisms with alkaline solution to enhance
metal uptake properties
Use of rLDM.TM. 1-6 and other ligninolytic enzymes in the
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2288
2289
2290
2291
2292
4,690,896
4,690,897
4,690,898
4,690,901
4,690,903
2293
4,690,906
2294
4,690,926
2295
4,691,009
2296
2297
2298
2299
2300
4,691,010
4,692,218
4,692,249
4,692,310
4,692,330
2301
4,692,333
2302
2303
4,692,403
4,692,404
2304
4,692,405
2305
2306
2307
2308
2309
2310
2311
4,692,406
4,692,407
4,692,408
4,692,409
4,692,410
4,692,411
4,692,412
2312
4,692,413
2313
4,692,414
2314
4,692,416
2315
2316
4,692,417
4,692,509
2317
2318
2319
4,693,842
4,693,893
4,693,898
2320
2321
2322
4,693,966
4,693,967
4,693,968
2323
2324
2325
4,693,969
4,693,970
4,693,971
bleaching of kraft pulp
Device for the determination of micro-organisms
Method for transformation of anaerobic microorganisms
DNA coding for a signal peptide and DNA containing the same
Silver methenamine staining method
Process for preparing organic fuels and chemicals from biomass
Nephelometric determination of HB.sub.s antigen with antibodycontaining microparticles
Boxazomycin A and B, new antibiotics containing benzoxazole
nucleus
Hybrid proteins produced by an ultrahigh prokaryotic expression
system
Hybrid cell line for producing monoclonal antibody to a human
early thymocyte antigen, antibody, and methods
Process for producing ethanol
Flotation process for sludge recovery and energy conversion
Substance K-259-2 and a process for producing the same
Process for accelerating antigen-antibody reaction
Antimicrobial and antitumor antibiotic M 9026 and its pure
individual factors 1, 2, and 3 and microbial process for production
thereof
Methods and compositions for the detection of acquired immune
deficiency syndrome
Method of measuring biological ligand by the use of enzymes
Monoclonal antibodies to antigen on activated human B-cells and
assay therefor, protein antigenic determinant therefor and method
of making same
Process and a reagent for the simultaneous determination of
fibrinogen and fibrinogen fission products in plasma
Method for the determination of Streptococcus mutans
Fermentation process for the production of polysaccharides
Method for producing L-aspartic acid
Infections bronchitis virus strains
Separation of specific biological cells by a biochemical filter
Method of preparing an autogenous vaccine
Use of rLDM.TM. 1-6 and other ligninolytic enzymes for the
decolorization of E1 effluent
Apparatus for automatically controlling the feed rate of alcohol
solution as raw material in a vinegar production process
Monoclonal antibodies reactive with shared idiotypes on human
antibodies to native DNA from patients with systemic lupus
erythematosus
Immunological identification test for group D streptococci using
achromopeptidase
Radioactive labeling of proteins with nucleosides or nucleotides
Cyanobacterium-produced bioemulsifier composition and solution
thereof
Vaccines for equine influenza
Novel baker's yeast and process for making bread
Human monoclonal antibodies from lymphocytes of patients with
malignant melanoma
Monitoring therapy results in body samples of receptor cells
Agent for quantitative determination of microorganisms
Reagent for use in a sandwich solid-phase enzyme-immunoassay
and process for employing same
Immunoassay using complement
Highly sensitive enzyme assay method
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2326
4,693,972
2327
2328
4,693,973
4,693,974
2329
4,693,975
2330
2331
4,693,976
4,693,977
2332
4,693,978
2333
4,693,979
2334
2335
2336
2337
4,693,980
4,693,981
4,693,982
4,693,983
2338
2339
2340
2341
4,693,985
4,694,069
4,694,070
4,694,074
2342
2343
4,695,384
4,695,392
2344
4,695,454
2345
2346
4,695,455
4,695,460
2347
2348
4,695,484
4,695,536
2349
2350
4,695,537
4,695,538
2351
2352
2353
4,695,539
4,695,540
4,695,541
2354
2355
2356
2357
4,695,542
4,695,543
4,695,544
4,695,545
2358
2359
2360
2361
4,695,546
4,695,547
4,695,548
4,695,549
2362
2363
4,695,550
4,695,551
2364
2365
4,695,552
4,695,553
Composition and method for rapid detection of microorganisms in
clinical samples
DNA sequences, recombinant DNA molecules and processes for
producing bovine growth hormone-like polypeptides in high yield
Processes for producing leucrose
Human hybridroma fusion partner for production of human
monoclonal antibodies
Process for the incorporation of foreign DNA into the genome of
dicotyledonous plants using stable cointegrate plasmids
Enzyme immobilization for producing cephalosporin antibiotics
Type II restriction endonuclease MaeI, a process for obtaining it
and the use thereof
Type II restriction endonuclease Mae II, a process for obtaining it
and the use thereof
New type II restriction endonuclease mae III, a process for
obtaining it and the use thereof
Preparation of inactivated viral vaccines
Enzymatically-treated guar gums
Reactor for cultivating biological material such as immobilized cells
Methods of concentrating ligands and active membranes used
therefor
Kibdelosporangium aridum SK&F-AAD-609
Water soluble xanthylium derivatives substrates
Process for the purification of HBsAg
Method for improving the phosphorus elimination capacity of a
lake
Magnetic particles for use in separations
Process for preparing hepatitis B surface antigen containing
particles in novel forms which are highly immunogenic
Cellular encapsulation of pesticides produced by expression of
heterologous genes
Synthetic, plasma-free, transfusible platelet storage medium
Process for forming moisture-permeable waterproof coating on
fabrics
Corneal storage system
Particles sensitized with detergent-treated antigen for agglutination
immunoassay
Human monoclonal antibodies to cell surface antigens
Process for quantitative determination of substrate treated with
oxidase
Quantitative determination of substrate treated with oxidase
Enzymatic detection of bacterial capsular polysaccharide antigens
cDNA clones coding for polypeptides exhibiting multi-lineage
cellular growth factor activity
Alpha Interferon GX-1
Process for the preparation of cholecystokinin antagonists
Culture and process for producing A41030 antibiotics
Transforming Bacillus stearothermophilus with plasmid vector pTB
19
Probe for electrofusion, electroporation, or like procedure
Gel inserts useful in electrophoresis
Metabolically active preparations obtained from yeast of any type
ATP: polynucleotide adenylyltransferase enzyme and method of
preparation thereof
Sampling apparatus for a biological reactor
Process and reagent for the determination of the hemoglobinhaptoglobin complex in the presence of free hemoglobin
Method for increasing agglutination of groups of cells to produce
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2366
4,695,623
2367
4,695,624
2368
2369
2370
4,695,956
4,696,286
4,696,746
2371
2372
4,696,747
4,696,794
2373
4,696,895
2374
2375
2376
4,696,896
4,696,897
4,696,898
2377
2378
2379
2380
2381
4,696,899
4,696,900
4,696,901
4,696,902
4,696,925
2382
4,696,980
2383
2384
4,698,142
4,698,224
2385
2386
2387
2388
2389
4,698,298
4,698,299
4,698,300
4,698,301
4,698,302
2390
2391
2392
2393
4,698,303
4,698,304
4,698,305
4,698,306
2394
2395
2396
2397
2398
2399
2400
4,698,307
4,698,308
4,698,309
4,698,310
4,699,669
4,699,670
4,699,785
2401
2402
2403
2404
4,699,786
4,699,789
4,699,790
4,699,875
improved cell layer interface in centrifuged blood sample using
antibodies
Consensus human leukocyte interferon
Covalently-modified polyanionic bacterial polysaccharides, stable
covalent conjugates of such polysaccharides and immunogenic
proteins with bigeneric spacers, and methods of preparing such
polysaccharides and conjugates and of confirming covalency
Apparatus and method of quantifying hemostasis using oscillations
from a transducer immersed in the blood sample
Coated transplants and method for making same
Two phase anaerobic digestion
Process for the elimination of nitrates by means of a
microbiological conversion in the presence of hydrogen gas
CL-1957D antibiotic compound and its production
Monoclonal anti-protein C antibody, its preparation and use
thereof
Gonococcal Pili processes for the preparation thereof and the use
thereof for the detection of and prevention of infections caused by
Neisseria gonorrhoeae
Process for preparing 2-keto-L-gulonic acid
Vector encoding hepatitis B surface antigen
Process for the preparation of human leukocyte and human
gamma interferon
Production of bacterial polysaccharides
Immobilization of microorganisms on a plastic carrier
Modular apparatus for cell culture
Cholecystokinin antagonist compounds
Sulfone activated thioether adsorbents for the separation of
proteins and the like
Free-flow electrophoretic separation method and apparatus
therefor
Production of alcoholic beverages
Competitive immunoassay protocal for targets including
lipoproteins and alpha-fetoprotein
Lipid-dependent diagnostic assays
Process and reagent for the determination of .alpha.-amylase
Angiogenic factor production
Enzymatic reactions using magnetic particles
Production of lactic acid by continuous fermentation using an
inexpensive raw material and a simplified method of lactic acid
purification
Method for producing hydrocarbon mixtures
Method of treating wood
Process for producing peroxidase
Recombinant DNA cloning vectors containing selectable genetic
markers for use in streptomyces and related organisms
Device for measuring the number of bacteria in superpure water
Germination floor systems
Apparatus for fermentation of organic material
Low D.E. starch hydrolyzates
Low D.E. starch hydrolyzates
Cell line producing feline leukemia virus
Enhanced large scale cultivation of bordetella pertussis cells for
vaccine production using lactoglobulin
Viral free semen and methods of producing the same
Antibiotic LL-C19004
Diagnosis of amyotrophic lateral sclerosis by neurotrophic factors
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2405
2406
4,699,876
4,699,877
2407
4,699,878
2408
2409
2410
4,699,879
4,699,880
4,699,881
2411
2412
4,699,882
4,699,883
2413
2414
2415
2416
2417
4,699,884
4,699,978
4,701,261
4,701,285
4,701,324
2418
2419
2420
2421
4,701,406
4,701,407
4,701,408
4,701,409
2422
4,701,410
2423
4,701,411
2424
2425
2426
2427
4,701,412
4,701,413
4,701,414
4,701,415
2428
2429
4,701,416
4,701,419
2430
2431
2432
4,701,420
4,701,421
4,701,558
2433
4,701,850
2434
4,702,909
2435
4,702,910
2436
4,703,001
2437
2438
2439
4,703,002
4,703,003
4,703,004
2440
2441
2442
4,703,005
4,703,007
4,703,008
2443
4,703,009
Nonradiometric polynucleotide probes
Methods and compositions for detecting human tumors
Process for the determination of the toxicity preventing activity of
human blood serum
Process for microbial production of an optically active 3-(3,4dihydroxyphenyl)serine
Method of producing monoclonal anti-idiotype antibody
Chamber for the treatment of cells in an electric field
Stable glucose isomerase concentrate and a process for the
preparation thereof
Process for producing N-acylneuraminate aldolase
Process and apparatus for the simultaneous application of a
multiplicity of liquid samples to an object stage
Site-specific chiral ruthenium (II) and cobalt (III) antitumor agents
Process for the separation of metals from aqueous media
Acyl phosphate salts and their use
Novel cell-cidal antibiotic 82-85-8A and its production
Assay for the detection of epigenetic toxic (non-genotoxic)
substances
Diagnosis of Alzheimer disease
Monoclonal antibody to activated macrophages
Detection of B-cell neoplasms
Method for the immunochemical determination of hepatitis B core
antigens
Bilirubin-specific enzyme preparation, assay compositions,
analytical elements and methods using same
Method and apparatus for preventing cross-examination of
biochemical test wells in a microtiter test plate
Method of producing inosine and/or guanosine
Method for producing ethanol from xylose-containing substance
Controlled atmosphere enclosure
Feline leukemia virus vaccine plasmids for fusion protein of the
gp70 envelope protein of FELV
Analysis of polymeric protein and protein products
Analytical compositions, elements and methods utilizing reduction
of ferric ion chelates to form detectable dyes
Determination of protecting anti-HBV immunoglobulins
Method for purifying aqueous acrylamide solution
Method and apparatus utilizing agar diffusion technique for
determining quantitative drug concentration parameter
Non-A, non-B hepatitis antigen, antigen compositions, vaccine and
diagnostic reagent
Common antigen (PSC-A) to Pseudomonas aeruginosa which
acts as an agent for pretecting Pseudomonas aeruginosa infection
Immunoassay for the detection of serum analytes using pH
dependent chastropic acids
Method for preparing coating compositions containing an
immunologically reactive species and elements containing same
Monoclonal antibody with a high affinity for digoxin
Synthesis of protein with an identification peptide
Expression vector carrying a gene coding for a phosphate-binding
protein, a method for preparing the same and a method for
preparing the same and a method for producing a polypeptide
using the same
Separation of volatiles from aqueous solutions by gas stripping
DNA sequences encoding erythropoietin
RDNA cloning vector pVE1, deletion and hybrid mutants and
recombinant derivatives thereof products and processes
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2444
2445
2446
2447
4,703,010
4,703,011
4,703,012
4,703,017
2448
2449
2450
4,704,193
4,704,274
4,704,275
2451
2452
2453
4,704,276
4,704,352
4,704,353
2454
2455
2456
4,704,354
4,704,355
4,704,356
2457
4,704,357
2458
2459
2460
4,704,358
4,704,359
4,704,360
2461
2462
2463
2464
4,704,361
4,704,362
4,704,363
4,704,365
2465
4,704,380
2466
4,704,460
2467
2468
4,705,604
4,705,678
2469
2470
2471
4,705,686
4,705,688
4,705,748
2472
4,705,749
2473
2474
4,705,750
4,705,751
2475
2476
4,705,752
4,705,753
2477
2478
4,705,754
4,705,755
2479
2480
2481
2482
4,705,756
4,706,463
4,707,287
4,707,291
Electrolytic bioreactor assembly and method
Thymidine kinase deletion mutants of bovine herpesvirus-1
High copy-number plasmid vectors, production and use thereof
Solid phase assay with visual readout
Covalently coupled cofactor modified electrodes and methods of
synthesis and use
Method for the purification of LPF-HA
Vaccine against rotavirus diseases
Compositions and methods for increasing the growth rate of meat
producing animals, improving the efficiency of feed utilization
thereby and enhancing lactation in lactating ruminants
L-ascorbate-2-phosphate salts in blood cell storage
Photoresponsive redox detection and discrimination
Virion assay method for use in in vitro screening of teratogens and
carcinogens
Assay utilizing ATP encapsulated within liposome particles
Method of diagnosing cartilage tissue abnormalities
Immortalized T-lymphocyte cell line for testing HTLV-III
inactivation
.DELTA..sup.1 -dehydrogenation with heat or air-dried B.
cyclooxidans
Protease and process for production and use thereof
Enzymatic degradation of lipopolysaccharide bioemulsifiers
Pharmaceutical compositions containing the cytidine
monophospate of 5-acetamido-3,5-dideoxy-D-glycero-Dgalactononulosaminic acid and a method for preparing said
compound
Recombinant cloning vehicle microbial polypeptide expression
Fermentation system
Composition and method for stabilization of dinucleotides
Method of stimulating the growth of macrophage-like cells utilizing
mitogenic peptides
Novel compounds for detecting the presence of hydrolytic analytes
in a test sample
Process for extracting poly-beta-hydroxybutyrates by means of a
solvent from an aqueous suspension of microorganisms
Sterile radioactive indium-containing aqueous solution
Process for the preparation of acellular Bordetalla pertussis
vaccine
Antibiotic LL-E19020 .alpha. and .beta.
Antigen associated with early detection of mammalian pregnancy
Process and reagent for the determination of glycerol with the use
of glycerol kinase
Promoter plasmid containing the promoter and use thereof in
transforming Bacillus
Process for preparation of multimeric plasma fibronectin
Process for the enzymatic hydrolysis of D-.alpha.-amino-acid
amides
Biologically active acrylonitrile-based copolymeric membrane
Biofouling side-stream apparatus (BSSA) for monitoring the
microbial growth in oilfield water systems
Apparatus for collecting lysozyme from egg white by adsorption
Method of determining the existence and/or the monitoring of a
pathological condition in a mammal
Recovery of microorganism having ice nucleating activity
Dry bleach stable enzyme composition
Enzymatic detergent composition
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2483
4,707,357
2484
2485
2486
4,707,359
4,707,364
4,707,438
2487
4,707,439
2488
4,707,440
2489
4,707,441
2490
4,707,442
2491
2492
2493
2494
2495
2496
2497
2498
2499
2500
4,707,443
4,707,444
4,707,445
4,707,446
4,707,447
4,707,448
4,707,449
4,707,450
4,707,493
4,707,542
2501
4,707,543
2502
2503
4,708,818
4,708,850
2504
2505
2506
4,708,862
4,708,871
4,708,872
2507
2508
4,708,875
4,708,929
2509
4,708,930
2510
2511
2512
2513
2514
2515
4,708,931
4,708,932
4,708,933
4,708,934
4,708,935
4,708,936
2516
2517
4,708,937
4,708,938
2518
2519
2520
4,708,944
4,708,948
4,709,015
2521
2522
4,709,016
4,709,020
Immunologically active peptides capable of inducing immunization
against malaria and genes encoding therefor
Insecticide composition for controlling insects which have an
aquatic breeding site
Composition for accelerating cheese aging
Immunoassay for breast cancer employing monoclonal antibodies
Screening test for reverse-transcriptase containing virus such as
non-A, non-B hepatitis, NANBH
Nucleic acid hybridization assay and detectable molecules useful
in such assay
Binding assays in automated apparatus with liposome compatible
surfactants
Hybrid cell line producing monoclonal antibody cytolytic to
Trichomonas vaginalis
Soluble interleukin-2 receptor as a disease indicator and a method
of assaying the same
Method for predicting the acceptability of coarsely ground beef
Intact gene and method of excising and cloning same
Stable haloperoxidase method
Fungal chloroperoxidase method
Immortal line of human fetal glial cells
Pichia pastoris yeast strains of enhanced tryptophan content
Specimen collection and test unit
19-epi-dianemycin as an anticoccidial and antibacterial agent
Immunogenic HbsAg derived from transformed yeast
Process for the preparation of detoxified polysaccharide-outer
membrane protein complexes, and their use as antibacterial
vaccines
Human immunodeficiency viruses associated with Acquired
Immune Deficiency Syndrome (AIDS), a diagnostic method for
AIDS and pre-AIDS, and a kit therefor
Self-contained portable apparatus for blood typing
Radioimmuno detection of human cancers using anti-tumor
monoclonal antibody
Antigenically active amino acid sequences
Antitumor antibiotic complex
Production of fermented alcoholic products having a low diacetyl
content
Methods for protein binding enzyme complementation assays
Monoclonal antibody to a human carcinoma tumor associated
antigen
Laminated rod having alternating detection and spacer layers for
binding assays
Method and device for biospecific affinity reactions
Immunoliposome assay-methods and products
.alpha.-amidation enzyme
(2-5')-Oligo (3'-deoxyadenylate) and derivatives thereof
Process for the continuous production of L-carnitine
Purified migration inhibitory factor also having colony stimulating
factor activity
Alcoholic fermentation
Protease adsorbent and process for purifying TPA utilizing the
same
Substantially purified tumor growth inhibitory factor
Monoclonal antibody to human suppressor T cells
Molecular analytical release tags and their use in chemical
analysis
Heptaose compounds and preparation thereof
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2523
2524
2525
4,709,023
4,709,819
4,710,370
2526
4,710,377
2527
2528
4,710,457
4,710,458
2529
2530
2531
2532
4,710,459
4,710,460
4,710,461
4,710,462
2533
2534
2535
2536
2537
4,710,463
4,710,464
4,710,465
4,710,466
4,710,467
2538
2539
2540
2541
2542
2543
2544
2545
2546
4,710,468
4,710,469
4,710,470
4,710,471
4,710,472
4,710,473
4,710,583
4,711,163
4,711,245
2547
2548
2549
2550
2551
2552
4,711,739
4,711,778
4,711,839
4,711,840
4,711,841
4,711,842
2553
2554
2555
4,711,843
4,711,844
4,711,845
2556
2557
2558
4,711,846
4,711,847
4,711,848
2559
4,711,849
2560
4,711,850
2561
4,711,851
2562
4,711,856
2563
2564
4,711,963
4,712,290
Process for the preparation of 7-amino-3-(3formamidopyridinium)methyl-3-cephem-4-carboxylate, and its use
for the synthesis of .beta.-lactam antibiotics
Method for preserving plated media and product
Method for detection of Cushing's syndrome in domestic animals
Antigens and monoclonal antibodies reactive against sporozoites
of Eimeria spp.
Monoclonal antibody for human hematopoietic glycoproteins and
method
Nylon strips for medical assay
Process and reagent for the determination of fibrin monomer in
plasma
Diagnostic applications of phosphofructokinase
Promoter derived from chloroplast DNA
Cell proliferation inhibitor and method of preparation
Recombinant DNA molecules capable of expressing HBV core
and surface antigens
Transcription terminators
Junction-fragment DNA probes and probe clusters
Method of cloning modified streptomycetes DNA
Process for preparing phenylalanine
Process for preparing L-carnitine and chemical intermediates
employed therein
Novel phosphotyrosyl protein phosphatase
Process for producing neuraminidase
Novel vector plasmids
Magnetic separation device
DNA plasmids
Dipeptides and process
Acetic acid fermentation process and apparatus
Sensor for components of a liquid mixture
Enzyme prespotter composition stabilized with water insoluble
polyester or polyether polyol
Inactivated rabies vaccine for veterinary use
Immune complex assay
Polymerization-induced separation immunoassays
Method for determining one or more antigens in a sample
Method for production of biologically active substances
Method and vector organism for controlled accumulation of cloned
heterologous gene products in Bacillus subtilis
Modified signal peptides
Portable temperature-sensitive control cassette
Process for the production of L-aspartyl-L-phenylalanine methy
ester or L-aspartyl-L-phenylalanine
Preparation of secretin
Site specific mutagenesis in alpha-1-antitrypsin
Construction of selectable shuttle cloning vectors for Thiobacillus
ferrooxidans
Pseudorabies virus mutants, vaccines containing same, methods
for the production of same and methods for the use of same
Test apparatus for determining a metabolic characteristic of
microorganisms
Nuclear binding assay for steroid receptor functionality in
cancerous cells
4-amino-2-methyl-3-phenyl-1-(2,4,6-trichlorophenyl)-3-pyrazolin-5one
Textile and method of manufacture
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2565
2566
2567
2568
2569
4,713,055
4,713,165
4,713,240
4,713,241
4,713,324
2570
4,713,325
2571
4,713,326
2572
2573
2574
2575
2576
2577
2578
2579
2580
2581
4,713,327
4,713,328
4,713,330
4,713,331
4,713,332
4,713,333
4,713,334
4,713,335
4,713,336
4,713,337
2582
2583
2584
4,713,338
4,713,339
4,713,340
2585
4,713,341
2586
2587
2588
2589
4,713,342
4,713,343
4,713,344
4,713,345
2590
2591
4,713,347
4,713,348
2592
4,713,352
2593
2594
4,713,448
4,713,449
2595
2596
2597
2598
4,713,975
4,714,606
4,714,611
4,714,613
2599
2600
2601
2602
2603
2604
2605
2606
2607
4,714,672
4,714,673
4,714,674
4,714,675
4,714,676
4,714,677
4,714,678
4,714,679
4,714,680
2608
2609
4,714,681
4,714,758
Artificially vascularized graft
Sensor having ion-selective electrodes
Vaccines based on insoluble supports
Bacterial insecticide and production thereof
Inverted latency specific binding assay
Hybridomas producing monoclonal antibodies specific for FeLV
p27
Coupling of nucleic acids to solid support by photochemical
methods
Determination of total creatine kinase or an isoenzyme with a
multilayer analytical element
Microbial Enzyme assays
Visual bioassay for rhizobium competition variants
Microbial production of A41030 antibiotics
T cell specific CDNA clone
Immobilization of biocatalysts on granular diatomaceous earth
Process for the saccharification of celluloses
Protein modification to provide enzyme activity
Gene for lignin degradation and uses thereof
Method for deletion of a gene from a bacteria
Porous spherical glass filtrating beads and method for the
manufacturing thereof
Polycistronic expression vector construction
Biodegradation of pentachlorophenol
Starter cultures of improved activity for dairy products and process
of making same
Novel isolate of trichoderma, fungicidal compositions containing
said isolate and use thereof
Biodegradation of halogenated aliphatic hydrocarbons
Hand operated press for tissue extraction
Fermentation methods and apparatus
Measurement of ligand/anti-ligand interactions using bulk
conductance
Fluorescent multiparameter particle analysis
Monoclonal antibody panel for early diagnosis and therapy of renal
carcinoma
Chemically modified hyaluronic acid preparation and method of
recovery thereof from animal tissues
Polysaccharide polymer made by xanthomonas
Dense star polymers for calibrating/characterizing sub-micron
apertures
Method of staining and identifying cells and compositions thereof
Stable composition of gamma-interferon
Method of suppressing cell growth by immunotherapy
Immunoassays involving complement lysing of chromophore
containing microcapsules
Method for measurement of concentration of substance
Chemotactic assay for immunogenicity
Stabilized sensitivity test disk
Protein modification to provide enzyme activity
Protein modification to provide enzyme activity
Temperature sensitive strain of bovine viral diarrhoea virus
In vitro propagation of grape
Human stem cells
Quadroma cells and trioma cells and methods for the production of
same
Surfactant composed of acylated collagen or acylated gelatine and
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2610
4,715,881
2611
4,715,899
2612
4,715,932
2613
2614
2615
2616
2617
4,716,030
4,716,101
4,716,102
4,716,103
4,716,104
2618
2619
2620
2621
2622
2623
2624
2625
4,716,105
4,716,106
4,716,107
4,716,108
4,716,109
4,716,110
4,716,111
4,716,112
2626
4,716,113
2627
4,716,114
2628
2629
2630
4,716,115
4,716,116
4,716,117
2631
2632
2633
4,716,123
4,716,217
4,716,219
2634
2635
2636
2637
4,717,545
4,717,652
4,717,653
4,717,654
2638
2639
4,717,655
4,717,656
2640
4,717,657
2641
2642
4,717,658
4,717,659
2643
2644
2645
2646
2647
2648
4,717,660
4,717,661
4,717,662
4,717,663
4,717,664
4,717,665
2649
2650
2651
4,717,666
4,717,667
4,717,668
a production process thereof
Control of eastern black nightshade with a fungal pathogen
Liquid cleaner containing inactivated protease for protein soiled
contact lenses
Method to separate polar organic compounds, in particular
aliphatic alcohols, from fermentation fluids
Method for detection of exogenous or ACTH stimulated
glucocorticoids in domestic animals
Rapid enzyme assay by product selective blot
Purified AIDS-associated virus ARV-2
Chemically active triazine support composition
Detecting presence of HCMV-specific IgM
Mini Mu containing plasmid and a method for rapid DNA
sequencing
Detecting polynucleotide sequences
Method for diagnosis of A.I.D.S.
Assaying anti-TP IgM antibodies for syphilis diagnosis
Immunoassay
Composition for assaying hydrogen peroxide
Process for producing human antibodies
Vectors for increased expression of cloned genes
Process for the production of an (S)-methyl or (S)-ethyl 4-amino-6fluorochroman-4-carboxylate
Procedure for the enhancement of the resistance to arsenite and
arsenate of Thiobacillus ferrooxidans and Bacillus subtilis
Derived nisin producing microorganisms, method of production
and use and products obtained thereby
Protein modification to provide enzyme activity
Monoclonal antibodies to factor VIIIC
Solid phase biological diagnostic assay via visual observation as
enhanced by Mie scattering
Hybrid lymphoblastoid-leukocyte human interferons
Adsorbent for protein purification
Device and method for chemical analysis of fluids with a reagent
coated light source
Composition for detection of peritoneal inflammation or infection
Method for identifying and characterizing organisms
Process for solid phase platelet antibody assay
Method and apparatus for distinguishing multiple subpopulations
of cells
Device for chemical analyses and use thereof
Predictive test for adverse reactions to iodinated radiographic
contrast media
Gram negative bacteria screening method with horseshoe crab
amebocyte lysate (LAL)
Novel method for determining cholinesterase activity
Detection of bacteria by fluorescent staining in an expanded buffy
coat
Biological indicator for sterilization processes
Thermal stabilization of alpha-amylase
Method of producing xanthan gum
Method for producing secondary metabolites of plants
Recovery of microbial lipase
Cloned streptomycete lividans excretable .beta.-galactosidase
gene
Colony replicating device
Plastic roller bottle for suspension cultures
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2652
2653
2654
2655
4,717,669
4,717,670
4,717,673
4,719,085
2656
2657
2658
2659
4,719,097
4,719,109
4,719,114
4,719,176
2660
2661
2662
4,719,177
4,719,178
4,719,179
2663
4,719,180
2664
4,719,287
2665
4,720,287
2666
2667
4,720,453
4,720,454
2668
2669
4,720,455
4,720,456
2670
2671
2672
4,720,457
4,720,458
4,720,459
2673
4,720,460
2674
4,720,461
2675
2676
4,720,462
4,720,463
2677
2678
2679
2680
2681
4,720,786
4,721,096
4,721,585
4,721,652
4,721,668
2682
4,721,669
2683
4,721,670
2684
4,721,671
2685
4,721,672
2686
4,721,673
2687
4,721,674
2688
2689
2690
4,721,675
4,721,676
4,721,678
Centrifugal film fermenter
Porcine beta FSH
Microelectrochemical devices
Mount for ammonia-sensitive test elements
Phosphates of resorufin derivatives and compositions thereof for
the determination of the activity of phosphatases
EM5596--an antibiotic
Encapsulated yeast
Enzyme-free diagnostic binding reagents
Production of complementary DNA representing RNA viral
sequences by recombinant DNA methods and uses therefor
Rearrangement process
Six base oligonucleotide linkers and methods for their use
Synthetic urogastrone gene, corresponding plasmid recombinants,
transformed cells, production thereof and urgastrone expression
Higher alkyl pyrrolidone extractants for water soluble phenolic or
carboxylic antibiotics
Low temperature thermal-chemical pretreatment process for peat
dewatering
Detecting environmental pollutants with protoplasts in alginate
matrix
Genetic probe used in the detection of adrenal hyperplasia
Progesterone assay method for mammals and monoclonal
antibody therefor
Trehalose lipid tetraesters
Selective production of ethyl acetate and acetaldehyde by
microorganisms
Heat sensitive bacterial alkaline phosphatase
Myelomas for producing human/human hybridomas
Process for preserving acid producing bacteria and compositions
produced thereby
Succinate-sensitive, nodulation-enhancing Rhizobium mutants for
use with legumes
Culture system for the culture of solid tissue masses and method
of using the same
Automated microbiological testing apparatus
Method of compensating for offset distortion in rows of
electrophoretic patterns
Process for replicating bone marrow in vitro and using the same
Process for the biological treatment of sewage
Composite for decomposing and adsorbing urea dissolved in liquid
Pre-electrophoretic nucleic acid hybridization
Chemical probes for left-handed DNA and chiral metal complexes
as Z-specific anti-tumor agents
Analytical reagent, analytical method, and multilayer chemicalanalytical element
Efficient prokaryotic expression system using portions of the E.
coli .beta .
CDNA and gene for human angiogenin (angiogenesis factor) and
methods of expression
Recovery and activation process for microbially produced calf
prochymosin
Process for obtaining lysozyme by a micro filtration from a starting
material based on white of egg
Production of hepatitis A virus in vitro utilizing a persistently virus
infected cell culture system
Novel thermophile isolate having thermostable hydrolytic activity
Triphasic mycoplasmatales culture device
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2691
4,721,679
2692
2693
4,722,741
4,722,840
2694
4,722,846
2695
4,722,848
2696
4,722,865
2697
4,722,887
2698
4,722,888
2699
4,722,889
2700
2701
2702
2703
2704
4,722,890
4,722,891
4,722,892
4,722,893
4,722,894
2705
2706
2707
2708
4,722,895
4,722,896
4,722,897
4,722,898
2709
4,722,899
2710
4,722,900
2711
4,722,901
2712
4,722,902
2713
2714
2715
2716
2717
2718
2719
4,722,903
4,722,906
4,722,917
4,722,924
4,723,000
4,723,004
4,723,020
2720
4,723,968
2721
2722
2723
4,724,144
4,724,145
4,724,146
2724
2725
4,724,202
4,724,203
2726
2727
2728
2729
2730
4,724,204
4,724,205
4,724,206
4,724,207
4,724,208
Tissue typing tray
Production of high methane content product by two phase
anaerobic digestion
Hybrid particle immunogens
Novel variant and process for producing light colored soy sauce
using such variant
Method for immunizing animals with synthetically modified
vaccinia virus
Poly(meth)acrylic network coated biologically or chemically active
substrate and method of making same
Phase partition separation of sperm based on seminolipid
expression
Cell line producing human monoclonal antibody which binds to
HTLV-I producing cells
Immunoassays using multiple monoclonal antibodies and
scavenger antibodies
Quantitative assay for human terminal complement cascade
activation
Methods and compositions for detection of Legionnaires' disease
Monoclonal antibodies against metal chelates
Reagents for enzyme immunoassay for apolipoprotein B
Method for the determination of ceruloplasmin activity
Synthetic peptides for the production of specific keratin protein
antibodies
Method for affinity purification of hybridoma antibodies
Viral enhancer DNA segments
Immobilization of biological cells in polytetrafluoroethylene matrix
Producing highly specific, low cross-reactive antibody by
immunizing with copolymer of D-glutamic acid and lysine
Method for increasing the milk clotting activity of thermolabile
rhizomucor pusillus rennet
Method and apparatus for the ultrasonic treatment of a dilute
alcoholic solution
Apparatus and method for culturing cells, removing waste and
concentrating product
Monoclonal antibodies specific to in vivo fragments derived from
human fibrinogen, human fiberin I or human fibrin II
Binding reagents and methods
Anti-I sorbent
Peptide substituted penicillins
Human interferon gamma and interleukin-2
Cephem compounds
Chromogenic amino acid esters and peptide esters
Method and apparatus for the purification of waste air containing
biologically decomposable impurities
Immuno-therapeutic composition of killed cells from
mycobacterium vaccae
Eimeria acervulina immunogens
Method for preparation herpes simplex virus subunit vaccine
Use of non-hybridizable nucleic acids for the detection of nucleic
acid hybridization
Caproylamidobiotinylated peroxidase
Diagnostic device for the detection of increased dehydrogenase or
oxidase and the use thereof
Diagnosis of Shigella dysenteriae
Protein production using hypertonic media
Modified siliceous chromatographic supports
Process for the production of solution stable alpha-amylase and
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2731
2732
4,724,209
4,724,210
2733
4,724,211
2734
2735
2736
2737
4,724,212
4,724,214
4,724,215
4,724,258
2738
2739
2740
2741
2742
4,725,148
4,725,406
4,725,436
4,725,443
4,725,535
2743
4,725,536
2744
2745
2746
4,725,537
4,725,538
4,725,539
2747
2748
2749
4,725,540
4,725,541
4,725,542
2750
2751
4,725,543
4,725,544
2752
2753
2754
2755
2756
4,725,545
4,725,546
4,725,547
4,725,548
4,725,549
2757
4,725,550
2758
4,725,557
2759
2760
2761
4,726,903
4,726,946
4,726,949
2762
2763
2764
2765
2766
4,726,954
4,727,018
4,727,019
4,727,020
4,727,021
2767
4,727,022
2768
4,727,023
2769
4,727,024
liquid alpha-amylase produced thereby
Process for producing restriction enzyme
Method for purification of influenza virus
Human monoclonal antibodies and lymphokines and cell lines
producing same
Murine hybridoma Lym-2 and diagnostic antibody produced
thereby
Apparatus for photosynthesis
Automated microbiological testing apparatus and method
Adult T cell leukemia virus antigen polypeptide
Turbidimeter employing a semiconductor laser diode and a
photodiode
Apparatus and method for diagnostic analysis of biological fluids
Method for controlling harmful fungi in cereals
Meat tenderization with proteolytic enzyme-containing oil
Promoter probe vectors
Reagent polynucleotide complex with multiple target binding
regions, and kit and methods
Assay, reagent and kit employing nucleic acid strand displacement
and restriction endonuclease cleavage
Method of assaying the presence of cancer cells
Method for analyzing plural oxidizable components in a liquid
Process for the preparation of amine-oxidase containing material,
so produced amine-oxidase containing material
Process for producing L-histidine by fermentation
Production of nylon 6,6 salt
Hybrid cell line for producing complement-fixing monoclonal
antibody to human suppressor T cells, antibody and methods
Method for purifying xylanase
Aryl sulfonyl fluoride inhibitors of elastase and chymotrypsin-like
enzymes
Method for purification of Japanese encephalitis virus
Method for purfication of rabic virus
Method and fermenter for growing tissue cells
Human and rat prolactin and preprolactin cloned genes
Novel mutation of the c-K-ras oncogene activated in a human lung
carcinoma
Production of fucosyl antigens and antibodies for recognizing
same determination of cancer associated carbohydrate linkage
using same and kit for the determination
Continuous flow separation or mixing by electrophoresis with
moving boundary sorption
Inactivated rabies vaccine for veterinary use
Irradiation of blood products
Lipolytic enzyme derived from a aspergillus microorganism having
an accelerating effect on cheese flavor development
Immunoregulation of transplantable tissue
Method and apparatus for immunoassays
Method for analysis of subpopulations of blood cells
Human monoclonal antibodies to cytokeratin
Methods for modulating ligand-receptor interactions and their
application
Preparations for use in solid phase immunoassays comprising
monoclonal antibodies covalently embedded in their immobilized
hybridoma cells
Binding assays involving formation and detection of light scattering
crystals
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2770
4,727,025
2771
4,727,026
2772
4,727,027
2773
4,727,028
2774
4,727,029
2775
2776
4,727,030
4,727,031
2777
4,727,037
2778
2779
4,727,039
4,727,040
2780
2781
4,727,137
4,727,138
2782
2783
2784
2785
4,728,427
4,728,502
4,728,516
4,728,604
2786
2787
2788
2789
2790
2791
4,728,605
4,728,607
4,728,608
4,728,609
4,728,610
4,728,611
2792
4,728,612
2793
4,728,613
2794
4,728,614
2795
2796
2797
2798
2799
2800
2801
4,728,637
4,728,660
4,729,875
4,729,947
4,729,948
4,729,949
4,729,950
2802
2803
2804
2805
2806
4,729,951
4,729,952
4,729,953
4,729,954
4,729,955
2807
4,729,956
2808
2809
4,729,957
4,729,958
Process and reagent for the fully enzymatic determination of urea
Method for direct saccharification of raw starch using enzyme
produced by a basidiomycete belonging to the genus Corticium
Photochemical decontamination treatment of whole blood or blood
components
Recombinant DNA cloning vectors and the eukaryotic and
prokaryotic transformants thereof
Apparatus and method for the pretreatment of biological
specimens for use in scanning electron microscopes
Preparation of porous polyvinyl alcohol gel containing an
immobilized enzyme
Nutrient for stimulating aerobic bacteria
Assay kit and method for the determination of antibody class and
subclass
Living bacterial preparation as well as method for preparing and
storing same
Sparger for fermentation and tissue culturing vessels
Purified protein having angiogenic activity and methods of
preparation
Human immune interferon
Reduction of trace elements to the elemental form by
microorganisms
Apparatus for the chemical synthesis of oligonucleotides
Method for the preservation of creamed cottage cheese
Process and reagent for the determination of transaminase
Methods for recognizing and diagnosing subsets of Alzheimer's
disease associated with immune system dysfunction, and for the
in vitro testing of possible therapeutic agents for treatment of same
Miniaturized yeast identification system
Bacterial screening system with enhanced shelf life
Recombinant growth hormone releasing factor
Method for producing L-glutamic acid
Production of phenylalanine with immobilized cells
Boxazomycin A and B, new antibiotics containing benzoxazole
nucleus
Method for the recovery of extracellular enzymes from whole
fermentation beer
Mutant human T cell line producing immunosuppressive factor and
method for obtaining such mutants
Complex of macromolecules extracted from mesenchymal cells for
treating chronic degenerative disease
Method of treating diseases arising from platelet hyperactivation
Device for performing immunochemical assays
DNA sequencing
Dry analytical element for .alpha.-amylase
System and methods for cell selection
Enhanced luminescent or luminometric assay
Process for the improvement of antibiotic production by in vivo
genetic recombination
Process for producing L-glutamic acid by fermentation
Optically active 4-hydroxy-2-cyclopentenones, and their production
pLS010 plasmid vector
Method of producing reverse transcriptase
Stabilized alcohol oxidase compositions and method for producing
same
Process for manufacture of L-asparaginase from erwinia
chrysanthemi
Method for improving the filterability of a microbial broth
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2810
2811
4,729,959
4,729,961
2812
2813
4,730,036
4,730,050
2814
4,731,245
2815
2816
4,731,323
4,731,324
2817
2818
4,731,325
4,731,326
2819
2820
2821
4,731,327
4,731,328
4,731,329
2822
2823
2824
2825
2826
4,731,440
4,732,155
4,732,608
4,732,681
4,732,736
2827
4,732,811
2828
4,732,847
2829
4,732,848
2830
2831
2832
2833
2834
2835
2836
2837
4,732,849
4,732,850
4,732,851
4,732,852
4,732,853
4,732,854
4,732,855
4,732,856
2838
2839
4,732,857
4,732,859
2840
2841
2842
2843
4,732,860
4,734,111
4,734,279
4,734,360
2844
2845
2846
4,734,361
4,734,362
4,734,363
2847
2848
2849
4,734,364
4,734,365
4,734,366
2850
2851
4,734,367
4,734,368
Glucose reference control for glucose test strips
Process for the detection and assay by erythroadsorption
Purifications of B-cell inducing factor (BIF) and B-cell growth factor
(BGF)
Novel enzyme derivatives
Vaccine, antigen and antibody for treating microorganisms of the
MCLS-type streptococcus sanguis
Methods of measurement and detection employing photosensitive
compositions and products
Viral lysis assay
Arrays of alternating nucleic acid fragments for hybridization
arrays
Disease diagnosis by detection of shed normal tissue antigens
Method for stabilizing recombinant DNA molecules and enhancing
the expression thereof in strains of Bacillus
Process for the production of muconic acid
Ethanol production by high performance bacterial fermentation
Method of somatotropin solubilization using dimethylsulfone and
naturation
Implantable chemoattractant system
Method for biological processing of metal-containing ores
Removal of contaminants
Analytical element for the detection hydrogen peroxide
Agarose-polyaldehyde beads and their biological application
affinity chromatography, hemoperfusion, cell separation, etc.
Monoclonal antibodies for DNA-RNA hybrid complexes and their
uses
Process for the determination of an immunologically-bindable
substance involving a Fab fragment
Multilayered chemical analysis material for analysis of aqueous
liquids
Frangible container with rupturing device
Immobilization of cells with a polyazetidine prepolymer
Site directed peptidase cleavage
Method of making chiral epoxy alcohols
Method of producing dextranase
Process for preparation of propionic acid
Transposable elements and process for using same
Process for producing enzyme capable of inactivating cytosolic
aspartate aminotransferase isozyme
Method for conferring bacteriophage resistance to bacteria
Process for determining the perkallikrein content and the partial
thromboplastin time of a plasma sample
Process and apparatus for cleaning styrene-polluted spent air
Combination of immunoglobulins with therapeutic agents
Colorimetric ethanol analysis method and test device
Low temperature-sensitive variant of lactobacillus bulgaricus and a
selection method therefor
Process for purifying recombinant proteins, and products thereof
Large scale production of DNA probes
Production of dextrose and maltose syrups using an enzyme
derived from rice
Process for liquefying starch
Biological process for L-fructose synthesis
Process to produce alpha-substituted derivatives of 3hydroxypropionic acid
Process for the bioconversion of fumarate to L-malate
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2852
2853
2854
2855
2856
2857
4,734,370
4,734,371
4,734,372
4,734,373
4,734,374
4,734,403
2858
4,734,439
2859
2860
4,734,491
4,734,492
2861
2862
2863
2864
2865
2866
2867
2868
4,735,697
4,735,724
4,735,776
4,735,778
4,735,794
4,735,800
4,735,801
4,735,895
2869
4,735,896
2870
4,735,897
2871
2872
2873
2874
2875
2876
4,735,898
4,735,899
4,735,900
4,735,901
4,735,902
4,735,903
2877
2878
2879
2880
2881
4,736,019
4,736,020
4,736,866
4,737,363
4,737,413
2882
4,737,453
2883
2884
2885
4,737,454
4,737,455
4,737,456
2886
4,737,457
2887
2888
2889
2890
4,737,458
4,737,459
4,737,460
4,737,461
2891
4,737,462
2892
2893
4,737,466
4,737,560
Antibiotic-producing microorganism culture
System for introducing noxious gas into an exposure chamber
Cell culturing methods and apparatus
Apparatus for enhancing cell growth, preservation and transport
Germination floor systems
Membrane polysaccharides which are useful as immunostimulants
Foam-containing polyurethane(urea) compositions and process for
the preparation thereof
DNA sequences encoding hybrid lymphoblastoid-leukocyte human
interferons
Macrolide antibiotic M 119
Method and apparatus for separating complex mixtures of bioorganic materials
Solids concentrating anaerobic digestion process and apparatus
Chemical manipulator
Microtiter plate
Method for drying biological specimens
Vaccines against rift valley fever virus
Novel non-reverting salmonella live vaccines
Cancer susceptibility test
Synthetic peptide and process of using same for the detection and
diagnosis of AIDS and pre-AIDS conditions
Method and kit for detecting polyriboadenosine segments and
messenger RNA
Monoclonal antibodies and method of identifying species using the
same
Detection of airborne microorganisms
Enzyme preparation for interesterification
Transformation of Candida albicans
Stabilized composition containing inositoltriphosphate
Micromonospora carbonacea var africana
Process for the separation of antifactor VIII:C antibodies, more
particularly usable for the purification of the blood plasma of a type
a hemophiliac
Purification of hTNF
Transgenic non-human mammals
Bacteroides nodosus vaccine
Chemorepellant compound
Sandwich immunoassay utilizing a separation specific binding
substance
Fast photochemical method of labelling nucleic acids for detection
purposes in hybridization assays
Analytical utilization of phagocyte cell lines
Reducing interference in ligand-receptor binding assays
Analytical composition, element and method for the determination
of hydrogen peroxide
Aminopyrazolinones, reagent containing them and the use thereof
in the enzymatic determinaton of hydrogen peroxide
Regulation and enhancement of enzyme production
Peroxidase and a process of its preparation
Novel bacteriolytic enzyme and process for preparing the same
Structural genes, plasmids and transformed cells for producing
cysteine depleted muteins of interferon-.beta.
N-acyldihydroresorufin derivatives, processes for their preparation,
reagents containing them and the use thereof for determining
hydrogen peroxide, peroxidate-acting compounds or peroxidase
Polymer beads
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2894
4,737,579
2895
4,738,682
2896
2897
2898
2899
2900
2901
4,738,727
4,738,773
4,738,782
4,738,844
4,738,845
4,738,846
2902
4,738,920
2903
2904
2905
2906
2907
2908
4,738,921
4,738,922
4,738,923
4,738,924
4,738,925
4,738,926
2909
2910
2911
4,738,927
4,738,928
4,738,929
2912
2913
2914
2915
2916
2917
2918
2919
2920
2921
2922
2923
4,738,930
4,738,931
4,738,932
4,738,958
4,740,306
4,740,456
4,740,457
4,740,458
4,740,459
4,740,460
4,740,461
4,740,462
2924
4,740,463
2925
4,740,464
2926
4,740,465
2927
2928
2929
4,740,466
4,740,467
4,740,468
2930
2931
2932
4,740,469
4,740,470
4,740,587
2933
2934
2935
2936
4,740,593
4,740,646
4,741,346
4,741,437
Monoclonal antibodies for human non-small cell lung carinomas
Clarification agent for colored cellulose fabrics and method for
treatment of such fabrics
Process for the preparation of an aqueous solution of a
heteropolysaccharide
Separator for magnetic particles from liquid phase
Method and apparatus for aseptic filtration
Modified (1-28) beta interferons
Modified (115-145) beta interferons
Vaccine for vesicular stomatitis virus
Method for assaying a biocomponent using 4-methoxy-1-naphthol
and hydrogen peroxide
Derivative of the tryptophan operon for expression of fused gene
products
Trans-acting transcriptional factors
Process for producing and separating cyclodextrins
Method for the production of 6-hydroxynicotinic acid
Method of increasing solubility of enzymes
Method for purification of HBs antigen
Gene coded for interleukin-2 polypeptide, recombinant DNA
carrying the said gene, a living cell line possessing the
recombinant DNA, and method for producing interleukin-2 using
the said cell
Method for cloning genes
Purified culture of streptomyces galanosa
Apparatus for continuously recovering ethanol from fermentable
sugar solutions
Human interferon-.beta. gene
Reaginic test for syphilis
Ansamycin antibiotic and its use as a medicament
Chromatographic column
Immunological methods for diagnosing neurocysticercosis
Method of diagnosis
Reagent for assaying creatine kinase
Fluorescence assay for microbial beta-lactamase
Process for measuring endotoxin and apparatus used therefor
Vectors and methods for transformation of eucaryotic cells
Non-phosphorylated peptides from casein-based material
Methods and artificial genes for antagonizing the function of an
oncogene
Fermentation process and microorganism for producing aconitic
acid
Heat-resistant sarcosine oxidase N and process for producing the
same
Induction of settlement and metamorphosis in Crassostrea
virginica by melanin-synthesizing bacteria
Methods for diagnosing syphilis
Concentrating immunochemical test device and method
Enzyme-granulating method and granular composition containing
enzyme
Biologically functional molecular chimeras
Inhibin and method of purifying same
Derived nisin producing microorganisms, method of production
and use and products obtained thereby
Preparation of indanes
Speciman collector
Self-contained indicator device
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2937
2938
2939
2940
4,741,898
4,741,900
4,741,901
4,741,903
2941
4,741,998
2942
4,741,999
2943
4,742,000
2944
4,742,001
2945
2946
4,742,002
4,742,003
2947
4,742,004
2948
4,742,005
2949
2950
4,742,006
4,742,007
2951
2952
4,742,008
4,742,114
2953
4,742,158
2954
4,742,159
2955
4,742,164
2956
2957
2958
2959
2960
4,742,690
4,743,445
4,743,446
4,743,453
4,743,535
2961
2962
2963
4,743,536
4,743,537
4,743,538
2964
4,743,539
2965
4,743,540
2966
4,743,541
2967
4,743,542
2968
2969
2970
2971
4,743,543
4,743,544
4,743,545
4,743,546
Stabilized stain composition
Antibody-metal ion complexes
Preparation of polypeptides in vertebrate cell culture
Novel enzyne derivatives
Monoclonal antibody to MHS-5: a new probe for sexual assault
analyses
Monoclonal antibodies useful in the identification of
microorganisms causing periodontal disease
Antibody to human progesterone receptor and diagnostic materials
and methods
Method of terminating isocitrate dehydrogenase reaction in an
analytical system
Test kit and method for determining the presence of blood in a
specimen and for testing the effectiveness of peroxidase
inactivating solution
Human transforming growth factor
Method for producing enzymatically active eucaryotic sod in
bacteria
Method for production of cellulolytic enzymes and method for
saccharification of cellulosic materials therewith
Fermentation process for the production of fructose from aqueous
mixtures of fructose and glucose and Zymomonas mobilis mutants
which can be used for such fermentation
Process for the preparation of L-tryptophan
Preparation of the enzyme beta-glucanase by fermentation of
fungi
Water-in-oil emulsions of amidase
Purification of hepatitis pre-S antigens by polymerized serum
albumin affinity binding
Digitalis antibodies, process for the preparation thereof and the
use thereof for the therapy of digitalis intoxications
Bacterial cellulose-containing molding material having high
dynamic strength
Apparatus and method for cryopreparing biological tissue for
ultrastructural analysis
Method for treatment of essential (hemorrhagic) thrombocythemia
Liver fluke antigens derived from juvenile fasciolo organisms
Fermentation of whey to produce propionic acid
Hybridization assay employing labeled probe and anti-hybrid
Method for enzyme immuno-determinations in heterogeneous
phase
Biological indicator for sterilization processes
Test for rheumatic fever and monoclonal antibodies useful therefor
Specific antibody to the native form of 2'5'-oligonucleotides, the
method of preparation and the use as reagents in immunoassays
or for binding 2'5-oligonucleotides in biological systems
Method for diagnosis of subclassifications of common varied
immunodeficiency disease group
Luminescent substrate preparation and its use in specific binding
assays
Method for forestalling the hook effect in a multi-ligand
immunoassay system
Method for enhancing and/or accelerating immunoassay detection
of human carcinoma tumor associated antigen in a pathology
sample
Method for measuring substances by enzyme immunoassay
Hollow porous microspheres containing biocatalyst
Controlled gene excision
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2972
2973
2974
4,743,547
4,743,548
4,743,549
2975
2976
4,743,550
4,743,551
2977
2978
4,743,552
4,743,553
2979
2980
2981
4,743,554
4,743,555
4,743,556
2982
4,743,559
2983
2984
2985
2986
4,743,561
4,743,562
4,743,594
4,743,678
2987
2988
2989
2990
2991
4,743,681
4,743,689
4,744,760
4,744,868
4,744,907
2992
4,744,933
2993
4,744,982
2994
4,744,983
2995
2996
4,744,985
4,745,051
2997
4,745,053
2998
2999
3000
4,745,054
4,745,055
4,745,056
3001
4,745,057
3002
3003
4,745,058
4,745,059
3004
3005
4,745,060
4,745,061
3006
3007
4,745,062
4,745,063
3008
4,745,064
Method of producing L-phenylalanine
Plant cell microinjection technique
Hydrogen peroxide-forming sarcosine oxidase
Method for improving the partition coefficient in enzyme-containing
systems having at least two phases
Purification of microbial rennet from Mucor miehei
Method for growth in tissue culture of normal colonic epithelial
cells and method for determination of preneoplastic color cells
Synthetic genes for bovine parainfluenza virus
Recombinant DNA expression vector encoding for foot and mouth
disease virus proteins
Biologically pure culture of Streptomyces sandaensis No. 6897
Petri dish
Method for the determination of redox reactions using iodate to
eliminate ascorbic acid interference
Luminescent assay with a reagent to alter transmitive properties of
assay solution
Purified human cytomegalovirus protein
Antibiotic, antitumor compounds and their use
Method and products for detection of human T cell leukemia virus
Hybrid cell line for producing monoclonal antibody to a human T
cell antigen, antibody, and methods
Antibiotic derivative of adenine
Colloidal sized metal-polysaccharide particles
Distillation column and method
Blood cell separation
Process for encapsulation and encapsulated active material
system
Human monoclonal antibody reactive with polyribosylribitol
phosphate
Immunogenic protein or peptide complex, method of producing
said complex and the use thereof as an immune stimulant and as
a vaccine
Novel substances having carcinostatic and immunostimulating
activity, process for preparing the same and carcinostatic agent
containing the same
Method for producing a recombinant baculovirus expression vector
Process for producing human interferon and method for assaying
the interferon productivity of blood
Enzymic method of detecting analytes and novel substrates
therefor
Fused protein for enzyme immunoassay system
Streptomyces secretion vector
Method, vectors and transformants for high expression of
heterologous polypeptides in yeast
Method for producing cellulosic fibers and microcrystalline
cellulose
Process for the preparation of L-phenylalanine
Methods and compositions for the detection of Familial
Hypercholesterolemia
Novel d-aminoacid transaminase and its use
Plasmid vectors for cloning and expression of a protein in a
microorganism, comprising at least one promoter for expression of
.beta.-glucosidase in yeasts; microorganisms containing these
plasmids; a fermentation process and the enzymes obtained
Method for separating rennet components
Process for the degradation of s-triazine derivatives in aqueous
solutions
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3009
3010
3011
3012
3013
4,745,065
4,745,066
4,745,067
4,745,068
4,745,069
3014
3015
3016
4,745,180
4,745,182
4,745,759
3017
3018
3019
3020
3021
4,745,771
4,746,435
4,746,511
4,746,512
4,746,517
3022
3023
4,746,539
4,746,604
3024
3025
4,746,605
4,746,606
3026
3027
3028
4,746,607
4,746,608
4,746,609
3029
3030
4,746,610
4,746,611
3031
3032
3033
3034
3035
3036
4,746,612
4,746,613
4,746,614
4,746,615
4,746,650
4,747,685
3037
4,748,020
3038
4,748,021
3039
3040
3041
4,748,109
4,748,110
4,748,111
3042
4,748,112
3043
4,748,113
3044
4,748,114
3045
3046
3047
4,748,115
4,748,116
4,748,117
3048
3049
3050
4,748,118
4,748,119
4,748,120
Genes conferring on yeasts a resistance to herbicides
Method for producing optically active glycol derivatives
L-aminoacylases
Dispersion tool
Cloning vectors for expression of exogenous protein
Solubilization of proteins for pharmaceutical compositions using
heparin fragments
Herpes virus specific immunological materials and methods
Kidney preservation machine
Apparatus and method for cryopreparing biological tissue for
ultrastructural analysis
Biochemical process for purifying contaminated water
Lipopolysaccharide and process for preparation thereof
Anticariogenic or antiperiodontitic agent
Production of beer
Purification of cancer-associated protein and preparation of
antibody thereto
Specific binding assays utilizing a viable cell as a label
Process and a reagent for the determination of low density
lipoproteins (LDL)
Bilirubin-specific enzyme and its analytical use
Use of substituted quinone electron transfer agents in analytical
determinations
Process for producing peptides
Restriction endonuclease cleaving palindromic DNA
Efficient use of thermal energy from an internal combustion engine
in ethanol production
Process for recovering cellulases
Aotus interspecies hybridomas and monoclonal receptors
produced thereby
Poultry diseases bacterin preparation
Extraction device
Sterilizable fluidized bed fermenter
Polycyclic ether antibiotic
Biological microparticle inspection apparatus
Vaccine for diseases of staphylococcus aureus and methods of
preparation
Antifungal compositions containing trichoderma active against
fusarium
Assay method and reagent to determine antibodies to
papillomavirus virions
Immunoassay for HTLV-III antigens
Nucleic acid-protein conjugate used in immunoassay
Methods and compositions relating to regression-associated
antigens
Compositions and methods for the diagnosis of gastrointestinal
disorders involving urease
Test strip for collecting of blood sugar daily profiles and process
for its preparation
Substrate formulation in 2-amino-2-methyl-1-propanol buffer for
alkaline phosphatase assays
Peptide substrates for determination of protease activity
Method for forming amphotericin B crystals in fermentation broth
Construction of arsenic resistance vectors for Thiobacillus
ferrooxidans
Process for altering and regulating gene expression
Photochemical decontamination treatment of whole blood or blood
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3051
3052
3053
3054
4,748,121
4,748,122
4,748,123
4,748,124
3055
3056
3057
4,748,127
4,748,129
4,748,233
3058
4,748,234
3059
3060
3061
4,749,458
4,749,511
4,749,559
3062
3063
3064
4,749,566
4,749,568
4,749,570
3065
3066
3067
4,749,571
4,749,620
4,749,647
3068
4,749,648
3069
3070
4,749,649
4,749,650
3071
3072
3073
3074
4,749,651
4,749,652
4,749,653
4,749,654
3075
4,749,670
3076
3077
3078
4,749,797
4,750,454
4,750,496
3079
3080
3081
3082
3083
3084
3085
4,751,003
4,751,007
4,751,077
4,751,078
4,751,079
4,751,080
4,751,081
3086
3087
3088
4,751,083
4,751,084
4,751,177
3089
4,751,178
3090
4,751,179
components
Porous glass fibers with immobilized biochemically active material
2,5-diketo-D-gluconic acid reductase
Continuous fermentation device
Compartmentalized cell-culture device and method
Process for the detection of biodegradable and toxic substances in
aqueous solutions
Assay method employing fluorescent cell incorporative dye
Alpha-interferon Gx-1
Process for recovering refractile bodies containing heterologous
proteins from microbial hosts
Free-flow electrophoretic separation method and apparatus
therefor
Contact lens cleaning solutions containing endoproteinase lys-C
Method for detecting melanin-containing matter
Pharmaceutical composition comprising a combination of at least
one immunotoxin and at least one mannose-containing polymer
Rubradirin treatment of methicillin-resistant staph
Targeting conjugates of albumin and therapeutic agents
Physiologically-active novel substance "Aldostatin" and production
method thereof
Encapsulated active material system
Polymerization-induced separation assay using recognition pairs
Agent for the determination of esterolytic and/or proteolytic
enzymes
Microbial .DELTA.1-dehydrogenation process using a scavenger
of toxic oxygen
Bacillus containing a 5'inosinate dehydrocenase gene
Process for enzymatically saccharifying starch-containing rawmaterials
Lactic acid process
Enzyme immobilization on non-porous glass fibers
Method and apparatus for the submerged growth of cell cultures
Selective regeneration of mediators in the presence of a catalyst
and surfactant
Tetra-alkyl-2,2,5,5-cyclohexanone-4-01-1 compounds and their
sulphonyl derivatives, the process and the intermediates for
preparing them and their use in the synthesis of cis-cyclopropane
lactones
Manure digester and power generating system
Method and apparatus for measuring blood glucose concentration
Crossflow microfiltration process for the separation of
biotechnologically produced materials
Method for filtering Bacillus subtilis
Interferons with novel cysteine pattern
Process for the purification of gamma interferon
Infectious bronchitis vaccines
Vaccine against rotavirus diseases
Chitinase-producing bacteria
Production of neutralizing antibodies by polypeptide VP1 of
enteroviruses and by oligopeptide fragments of polypeptide VP1
Tissue plasminogen activator from normal human colon cells
Methods and kits for performing nucleic acid hybridization assays
Substrates, compositions, elements and methods for the
determination of gamma-glutamyltransferase
Method and reagents for differential determination of four
populations of leukocytes in blood
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3091
4,751,180
3092
3093
4,751,181
4,751,182
3094
3095
3096
4,751,183
4,751,184
4,751,286
3097
4,751,287
3098
3099
4,751,348
4,752,284
3100
3101
4,752,301
4,752,372
3102
4,752,468
3103
3104
4,752,473
4,752,474
3105
4,752,562
3106
3107
4,752,563
4,752,564
3108
4,752,565
3109
3110
4,752,566
4,752,567
3111
3112
3113
4,752,568
4,752,569
4,752,570
3114
3115
4,752,571
4,752,572
3116
3117
4,752,573
4,752,574
3118
3119
4,752,575
4,752,576
3120
3121
3122
3123
3124
4,752,577
4,752,578
4,752,579
4,752,580
4,752,581
3125
4,752,582
3126
3127
4,752,583
4,752,584
Expression using fused genes providing for protein product
Methods and compositions useful in the diagnosis and treatment
of autoimmune diseases
Process for preparing L-carnitine from DL-carnitine
Monoclonal antibody that recognizes a structure common to
human interleukin-2 (TCGF) and to the light lambda chain of
human immunoglobulin and lines of hybridoma cells that produce
these monoclonal antibodies
Selective test pack feeder for biochemical analyzing apparatus
Protein label and drug delivery system
Human leukocyte interferon N and a method of producing same in
bacterial cells
Nicotiana plants with both altered polyamine levels and flower
structures and method for obtaining these plants
Artificial gravity intracellular molecular extraction
Method to due cotton and other substrates with a micro-organism
biomass containing indigo
Moving wall, continuous flow electronphoresis apparatus
Method of controlling plant feeding mites with the fungus
Neozygites floridana
Expression of glycosylated human influenza hemagglutinin
proteins
Live rabies vaccine
Detection of serum antibody and surface antigen by radial partition
immunoassay
Monoclonal antibody for recovery of leukocytes in human
peripheral blood and method of recovery employing said
monoclonal antibody
Fermentation method and apparatus
Cell line producing AIDS viral antigens without producing
infectious virus particles
Displacement polynucleotide method and reagent complex
employing labeled probe polynucleotide
Method of visualizing individual submicroscopic metal particles
Labeled hydantoin conjugate and its use in analytical element and
immunoassays
Sialylated Lewis.sup.x epitope, antibodies and diagnosis
Process for the determination of peroxidase
Method for determining certain bacterial polypeptides and
antibodies directed against them
Lipid vesicles containing labeled species and their analytical uses
Use of tetrahydrobiopterin to enhance the proliferative activity of
interleukin-2 on T cells
Chimeric cloning vectors for use in streptomyces and E. Coli
Lymphotoxins with antitumor activity and method for producing
same
Expression of .alpha.-1 antitrypsin in yeast
Method for using a novel transcriptional- and translationalactivating sequence in streptomyces
Collagenase inducing factor
Monosaccharides from corn kernel hulls by hydrolysis
Process for preparing Xanthomonas heteropolysaccharides
Novel compounds
Monoclonal antibodies to human glycophorin A and cell lines for
the production thereof
Monoclonal antibodies to human hemoglobin S and cell lines for
the production thereof
Process for the production of inoculum for anaerobic fermentation
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3128
4,752,585
3129
4,752,586
3130
4,752,603
3131
4,752,605
3132
3133
3134
3135
4,753,349
4,753,670
4,753,795
4,753,797
3136
3137
4,753,873
4,753,874
3138
3139
3140
3141
3142
3143
3144
3145
3146
4,753,875
4,753,876
4,753,877
4,753,878
4,753,879
4,753,880
4,753,881
4,753,882
4,753,883
3147
3148
4,753,884
4,753,885
3149
4,753,886
3150
3151
3152
4,753,887
4,753,894
4,753,959
3153
4,753,983
3154
3155
3156
3157
3158
4,755,208
4,755,304
4,755,355
4,755,381
4,755,457
3159
3160
4,755,458
4,755,459
3161
4,755,460
3162
4,755,461
3163
3164
3165
4,755,462
4,755,463
4,755,464
3166
3167
4,755,465
4,755,466
of coenzyme B.sub.12
Oxidation-resistant muteins
Apparatus for encapsulating biological active substances into
erythrocytes
Plasminogen activator and pharmaceutical composition having
thrombolytic activity
7-chloro-4a-hydroxy-8-methoxytetracycline, antibiotic
compositions containing them and a method of using
Laboratory test kit and method for preserving laboratory
specimens
Herbicide
Modified (80-113) beta interferons
Enhancing platelet morphology prior to patient use
Peptides for the diagnosis of HTLV-III antibodies, their preparation
and use
Rapid mutation testing system for human cells
Method for assaying proteases with tagged proteinaceous
inhibitors
Marker genes in pseudomonad bacteria
Cephalosporium acremonium
Microorganism identification technique
Modified tissue plasminogen activators
Method of selection for spiramycin resistance in streptomyces
Purified enzyme and process therefor
Urease and process for preparation thereof
Enzyme deregulation
Pseudorabies virus mutants, vaccines containing same, methods
for the production of same and methods for the use of same
Foam control in the sugar industry and in the yeast industry
Plasmid PHJL210 and related bifunctional cloning vectors for use
in streptomycetes
Controlled environment vitrification system for preparation of
liquids
Monoclonal anti-human breast cancer antibodies
Antibiotic lactone compound
Polymeric matrix for affinity chromatography and immobilization of
ligands
Biological control of wild poinsettia and other weedy spurges with
a fungal pathogen
Method of purifying ground water
Trace level oxygen detector for anaerobic atmospheres
Klebsiella capsular polysaccharide vaccine
Method for detecting HTLV-III neutralizing antibodies in sera
Composition and method for the detection of the presence of a
polynucleotide sequence of interest
Detection of gonococcal infections using monoclonal antibodies
Bovine antigen glycoprotein, related antibody, and use in detection
of pregnancy in cattle
Tableted blood plasma microconcentrated thromboplastin
coagulation reagent
Analytical process and agents for the detection of esterolytic
and/or proteolytic enzymes
Process for preparing steroids
Preparation of plasmid DNA and products thereof
Secretion of correctly processed human growth hormone in E. coli
and Pseudomonas
Process for producing L-phenylalanine
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3168
4,755,467
3169
4,755,468
3170
3171
3172
4,755,472
4,755,610
4,756,828
3173
3174
4,756,831
4,756,832
3175
3176
3177
3178
3179
3180
3181
3182
3183
3184
3185
4,756,834
4,756,884
4,757,000
4,757,001
4,757,002
4,757,003
4,757,004
4,757,005
4,757,006
4,757,007
4,757,008
3186
4,757,009
3187
3188
3189
3190
4,757,010
4,757,011
4,757,012
4,757,013
3191
3192
3193
3194
3195
4,757,014
4,757,015
4,757,016
4,757,017
4,757,018
3196
4,757,019
3197
4,757,020
3198
3199
4,757,021
4,757,022
3200
3201
3202
3203
4,757,024
4,757,052
4,757,134
4,758,323
3204
3205
3206
3207
3208
4,758,345
4,758,349
4,758,356
4,758,417
4,758,428
3209
4,758,507
Method for the production of sorbitol and gluconate
Inocula of low water activity with improved resistance to
temperature and rehydration, and preparation thereof
Stable composition for the determination of peroxidatively active
substances
Hapalindoles
Chromatographic strip having non-compressed edges
Process and apparatus for removal of nitrate from surface and
ground water, in particular drinking water
Enzymatic process
Phase supports for the partition chromatography of
macromolecules, a process for their preparation and their use
Capillary flow device
Process for assaying ATL virus antibody and reagent therefor
Method of measuring biological ligand by utilizing amylase
Method and kit for the estimation of serum immunoglobulin
Method for the detection of cancer
Chromatographic devices having modified edges
Method and cell line for obtaining plasminogen activators
Human factor VIII:C gene and recombinant methods for production
Process for preparing hydrolyzed products of soy protein
Enzyme immobilization in a macroporous non-ionic resin
Recombinant DNA having a phosphoenol pyruvate carboxylase
gene inserted therein, bacteria carrying said recombinant DNA
and a process for producing amino acids using said bacteria
Production of clostridium acetobutylicum mutants of high butanol
and acetone productivity, the resultant mutants and the use of
these mutants in the joint production of butanol and acetone
Herbicide resistant tobacco
Ascorbic acid intermediates and process enzymes
Cloning vehicles for polypeptide expression in microbial hosts
Immobilization of biologically active protein on a polymeric fibrous
support
Phenylalanine ammonia lyase-producing strains
Process for stabilizing the activity of peroxidase in solution
In vitro cell culture system
Myeloma cell lines and uses thereof
Method for obtaining pure, stable tissue cultures of human
melanocytes
Novel expression plasmids containing the full cDNA sequence of
calf prochymosin
Recombinant plasmid and microbial strain transformed by said
plasmid
Biological fluid measuring device
Immune complex detection method and article using
immunologically non-specific immunoglobulins
Method of preserving blood
IgA binding protein
Assay systems using more than one enzyme
Anaerobic microbial dissolution of lead and production of organic
acids
Separation process for biological media
Process for preparing Xanthomonas heteropolysaccharides
Gas treatment process
Multiclass hybrid interferons
Products displaying the antigenicity of hepatitis B virus e antigens
and methods of producing those antigens
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3210
3211
3212
4,758,508
4,758,509
4,758,510
3213
4,758,511
3214
4,758,512
3215
3216
4,758,513
4,758,514
3217
4,758,515
3218
3219
3220
3221
4,758,516
4,758,517
4,758,518
4,758,522
3222
4,758,524
3223
3224
3225
4,758,549
4,758,583
4,758,656
3226
3227
4,759,344
4,759,828
3228
3229
3230
3231
4,759,927
4,759,928
4,760,017
4,760,018
3232
3233
4,760,019
4,760,020
3234
3235
4,760,021
4,760,022
3236
3237
3238
3239
3240
3241
3242
3243
4,760,023
4,760,024
4,760,025
4,760,026
4,760,027
4,760,028
4,760,067
4,761,366
3244
3245
3246
4,761,367
4,761,368
4,761,369
3247
3248
3249
3250
4,761,370
4,761,371
4,761,372
4,761,373
Analytical process and agents for the detection of esterolytic
and/or proteolytic enzymes
Microbe growth detection
Simplified in-vitro interferon production
CDNA clones coding for polypeptides exhibiting IGE binding factor
activity
Hosts and methods for producing recombinant products in high
yields
Human T or B cell lines and a process for producing
immunologically active substances using the same
Ascorbic acid intermediates and process enzymes
Process for the preparation of a low-glucose digestion product
from inulin-containing parts of plants
Molecular cloning and characterization of a further gene sequence
coding for human relaxin
Process for growth of treponema hyodysenteriae
D-2-haloalkanoic acid halidohydrolase
Immunoassay for human chromogranin A
Monoclonal antibodies with specificity for crosslinked fibrin
derivatives and assay for said derivatives
Lymphokine, monoclonal antibody specific to the lymphokine and
their production and uses
Method and agents for inhibiting protein aging
Novel human interferon-gamma polypeptide derivative
Wang's tubules for sperm preparations used for IVF-ET-GIFT and
artificial inseminations
Glucose electrode and method of determining glucose
Vaccine against Potomac horse fever and method of preparation
therefore
Antibiotic: Treponemycin
Arabinonucleic acid probes for DNA/RNA assays
Rapid method for the detection of beta-lactamase in body fluids
Antigenic preparation and diagnostic method for identification of
nocardia infections
Method for testing biocompatibility
Biological response modifier having cell differentiation-induction
activity and process for production thereof
Stabilized plasmids
[21-leucine] human urogastrone, corresponding gene,
corresponding recombinant plasmid, transformed cell and process
for production thereof
Immobilization of enzymes
Modified enzymes and methods for making same
Monoclonal antibody
Microbiological desulfurization of gases
Bioreactor apparatus with surface aerator screen
Allylsulfoxide enzyme inhibitors
Medium, apparatus and method for cell separation
Vectors suitable for detection of eukaryotic DNA regulatory
sequences
Method and agents for measuring protein aging
Process for measuring calcium levels in biological fluids
Method for determining the presence of bacteria in body fluid
specimens containing bacterial inhibitors
Insulin receptor
Mutant enterotoxin of E. coli
Herbicide resistance in plants
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3251
3252
4,761,374
4,761,375
3253
4,761,376
3254
3255
3256
3257
3258
3259
3260
3261
3262
4,761,377
4,761,378
4,761,379
4,761,380
4,761,382
4,762,711
4,762,714
4,762,779
4,762,780
3263
3264
4,762,781
4,762,782
3265
4,762,783
3266
3267
4,762,784
4,762,785
3268
4,762,786
3269
3270
3271
4,762,787
4,762,788
4,762,789
3272
3273
4,762,790
4,762,791
3274
4,762,792
3275
4,762,793
3276
4,762,794
3277
4,762,795
3278
3279
3280
3281
3282
3283
3284
4,762,800
4,762,825
4,762,914
4,762,923
4,764,368
4,764,369
4,764,370
3285
4,764,371
3286
3287
4,764,372
4,764,373
3288
4,764,459
Thermally stable tryptophanase, process for producing the same,
and thermally stable tryptophanase-producing microorganism
Human interleukin-2 cDNA sequence
Facultatively anaerobic microorganism for degrading toxic waste
materials
Human-human hybrid cell lines that produce antibodies against
antigenic determinants on cancer cells
Microbiological testing apparatus
Biological specimen collection device
Fermentation cell for continuous operation
Immunological procedure for detecting or quantifying substances
Live vaccine for bovine babesiosis
Preparation of retrovirus-free immunoglobulins
Compositions and methods for functionalizing nucleic acids
Method and composition for screening and diagnosing "HCMV"
Antibodies capable of specifically identifying haptenic groups, their
preparation and their use and to new antigens permitting their
preparation
Assay for Beta-lactam antibiotics
Process and reagent for the determination of the folliclestimulating hormone and monoclonal antibodies suitable therefor
Fermemtation process for the high level production of bovine
growth hormone
Novel method and compositions for introducting alien DNA in vivo
Vectors and conditions which allow genetic transformation of
cephalosporium
Anti-human IGM immunoadsorbent and process for producing said
immunoadsorbent
Process for producing cellulolytic enzymes
Serodiagnostic reagent for entamoeba histolytica
Process for microplant propagation through increased multiple
shoot formation
Human immune interferon
Cholesterol-rich fraction useful in culture media and process of
producing same
Process for the biotechnological preparation of optically active
alpha-arylalkanoic acids
Apparatus for contacting biological cell systems with a perfusion
fluid
Device based on an inorganic crystalline matter connected to a
source of energy and use of said device for improving bacterial
metabolism
Monoclonal antibodies to cell surface antigens of human
teratocarcinomas
Polysaccharide RON substance
Truncated protein of interleukin-1
Fermentation analogs of virginiamycin M1
Acid-cleavable compound
Undenatured virus-free biologically active protein derivatives
Vaccine utilizing an avirulent strain of Salmonella typhimurium
Postharvest biological control of stone fruit brown rot by bacillus
subtilis
Compositions containing bacillus thuringiensis toxin toxic to
beetles of the order coleoptera, and uses thereof
Method of increasing the economic value of breeding stock semen
Enzyme-linked immunosorbent assay (ELISA) for determining
anti-bodies against herpes simplex virus (HSV) types 1 and 2 in
human sera
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3289
4,764,460
3290
3291
3292
4,764,461
4,764,462
4,764,463
3293
3294
3295
3296
3297
3298
3299
3300
3301
3302
4,764,464
4,764,465
4,764,466
4,764,467
4,764,468
4,764,469
4,764,470
4,764,471
4,764,472
4,764,473
3303
3304
3305
4,764,475
4,764,507
4,764,510
3306
3307
3308
4,764,593
4,764,606
4,765,901
3309
3310
4,765,902
4,765,903
3311
3312
4,765,961
4,765,972
3313
4,765,992
3314
4,766,062
3315
4,766,063
3316
3317
4,766,064
4,766,065
3318
3319
4,766,066
4,766,067
3320
3321
3322
3323
4,766,068
4,766,069
4,766,070
4,766,071
3324
3325
4,766,072
4,766,073
3326
3327
4,766,074
4,766,075
3328
4,766,076
Recombinant sigma NS protein
Tellurium and selenium compounds for the induction of in vivo and
in vitro production of cytokines
Detectably labeled cephalosporin assay for beta-lactamase
Platelet cyropreservation
Semisynthetic enzymes: apoproteins from heme proteins as
hydrolases
Human monoclonal antibody against group A red blood cells
Method for stabilizing an immobilized fibrinolytic enzyme
Preparation of an insoluble biocatalyst
Process for stabilizing the activity of peroxidase in solution
Streptokinase-coding recombinant vectors
Alkaline protease produced by a bacillus
Continuous bioreactor and process
Rehydratable instant active dried yeast
Chamber for the treatment of cells in an electrical field
Pancreas dependant immunoassay for determining
subpopulations of monoclonal antibodies to somatostatin.
Polysaccharide RDP substance
Antibiotic A42125 and process for its production
Manufacture and expression of genes for urogastrone and
polypeptide analogs thereof
7-formylaminocephalosporin compounds
Method for purifying waste water
Process for in situ biodegradation of hydrocarbon contaminated
soil
Purification of monomeric interferon
Apparatus for detection of certain nitrogen-containing gases using
chemiluminescence
Vinca alkaloid photoactive analogs and their uses
Stimulation of alcoholic fermentation by adsorption of toxic
substances with cell walls
Displacement polynucleotide assay method and polynucleotide
complex reagent therefor
Process and device for detecting the activity of a substance on a
micro-organism or on a mixture of micro-organisms
Displacement polynucleotide assay employing polyether and
diagnostic kit
Detection of cell membrane protein
Method of using bacteriophage lambda p.sub.1 promoter to
produce a functional polypeptide in streptomyces
Gene amplification
Cytochrome P-450MC gene, expression plasmid carrying the said
gene, yeasts transformed with the said plasmid and a process for
producing cytochrome P-450MC by culturing the said transformant
yeasts
Recombinant DNA which codes for interleukin-1 B
Fermentation process and substrate
Process for regenerating coenzymes
Vectors for in vitro production of RNA copies of either strand of a
cloned DNA sequence
Expression of biologically active PDGF analogs in eucaryotic cells
Thermostable Rhizomucor rennet having increased milk clotting
activity
Human tissue plasminogen activator
Method and buffered bulk starter media for propagation of useful
bacteria
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3329
3330
4,766,077
4,766,078
3331
3332
3333
4,766,079
4,766,112
4,766,160
3334
4,766,203
3335
3336
3337
4,766,224
4,767,557
4,767,600
3338
3339
4,767,622
4,767,623
3340
3341
3342
3343
3344
3345
3346
3347
3348
3349
3350
4,767,699
4,767,700
4,767,701
4,767,702
4,767,703
4,767,704
4,767,705
4,767,706
4,767,707
4,767,708
4,767,709
3351
3352
4,767,710
4,767,711
3353
3354
4,767,712
4,767,713
3355
3356
4,767,714
4,767,715
3357
4,767,717
3358
4,767,718
3359
4,769,061
3360
3361
3362
3363
3364
3365
3366
3367
3368
3369
3370
4,769,082
4,769,112
4,769,173
4,769,216
4,769,233
4,769,238
4,769,239
4,769,240
4,769,317
4,769,318
4,769,319
3371
4,769,320
Ice nucleation deficient microorganisms by genetic manipulation
Automated consecutive reaction analyzer
Method of using polypropylene glycol to improve movement and
intermixture of blood and other fluids in capillary tubes
Anthelmintic fermentation products of a microorganism
Photo-hardenable composition for bioactive coatings
New strain of Bacillus, a toxin derived thereof and a composition
for combating Coleoptera
Purification and activation of proteins from insoluble inclusion
bodies
Dry bleach and stable enzyme granular composition
Equipment for rapid, automatic chemical-clinical analysis
Method and materials for development of immunological
responses protective against malarial infection
Method of binding microflora and preparations therefor
Diagnostic reagent, kit and method employing polynucleotide
displacement, separation, enzymatic cleavage and adenosine
phosphate detection
Detection of particular nucleotide sequences
Poly I:C covalently bonded to polymer for diagnostic purposes
Paper strip assay for neisseria species
Method for assessing the fertility of male mammals
Protein-free culture medium
Apple pomace as substrate for microbial production of citric acid
Fixation of enzymes with bis-dithioesters
Immobilization of enzymes with a water-soluble glycidyl ether
Enzyme amplification and purification
Growth-related hormones
Cell lines for the production of monoclonal antibodies to human
glycophorin A
Bovine placental lactogen gene
Assay method using nad synthetase and a process for production
of the enzyme
Pure culture of Brevibacterium acetylicum AT-6-7, ATCC 39311
Method for the preparation of yeast chromatin for isolation of p20
polypeptide
Germination floor systems
Method of detecting and quantitating cell malignancy in biological
tissue
Fluorescent opioid reagents and methods of use thereof in the
detection of opioid receptors
Inhibition resistant 5-enolpyruvyl-3-phosphoshikimate synthase,
production and use
Method of pretreatment in saccharification and fermentation of
waste cellulose resource
Method for removing water from ethanol
Enzymatic detergent and bleaching composition
Device for detecting antigens and antibodies
Structure and properties of modified interferons
Synthesis of human virus antigens by yeast
Vaccine against varicella-zoster virus
Pili of neisseria and vaccine compositions containing same
Process for growing human epidermis, product thereof
Additive solution for blood preservation and activation
Nucleic acid probes for prenatal sexing
Immunoassay means and methods useful in human native
prothrombin and human abnormal prothorombin determinations
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3372
3373
4,769,321
4,769,322
3374
3375
3376
3377
3378
3379
3380
4,769,323
4,769,324
4,769,325
4,769,326
4,769,327
4,769,328
4,769,329
3381
3382
4,769,330
4,769,331
3383
3384
3385
3386
3387
3388
3389
3390
4,769,332
4,769,333
4,769,336
4,769,447
4,770,784
4,770,853
4,770,854
4,770,856
3391
3392
3393
3394
4,770,875
4,770,876
4,770,881
4,770,992
3395
3396
4,770,993
4,770,994
3397
3398
3399
3400
3401
4,770,995
4,770,996
4,770,997
4,770,998
4,770,999
3402
4,771,000
3403
3404
3405
3406
3407
4,771,001
4,771,002
4,771,003
4,771,008
4,771,125
3408
4,771,128
3409
3410
4,771,131
4,771,384
3411
3412
4,772,464
4,772,465
Assay method and reagent therefor
Quantification of endogenous histamine
Method for fractional determination of aspartate aminotransferase
isozymes, and composition therefor
Ethanol production
2-(Allenyl)penicillins
Expression linkers
Secretion vector
Expression of biologically active PDGF analogs in yeast
Preparation of optically pure D- and L- lactic acid
Modified vaccinia virus and methods for making and using the
same
Recombinant methods and materials
Method and composition for enhancement of growth of
mycobacteria
Personal diagnostic kit
Treatment of factor VIII inhibitors
Gamma-Glutamyl-4-azoanilides
Scrubbing process for high feed concentrations
Device for self contained solid phase immunodiffusion assay
Laboratory flask
Microtiter plate for blood typing
Process for preparation of improved mutant strain of Bordetella
bronchiseptica useful for live attenuated vaccine for protection of
B. bronchiseptica infection and live attenuated AR vaccine
produced therefrom
Microbiological production of livestock growth-promoting agent
Process for producing vinegar
Detection of specific DNA sequences by flow cytometry
Hybridoma tumor cell lines and their monoclonal antibodies to
thaumatin
Determination of carbohydrate acceptors
Detection of the sensitivity of cells to the effects of tumor necrosis
factor and lymphotoxin
Identification of individuals predisposed toward alcohol abuse
Thermostable bilirubin oxidase and production process thereof
Biochemical assay of aldehydes
High yield production of active Factor IX
Structural genes encoding the various allelic and maturation forms
of preprothaumatin, recombinant cloning vehicles comprising said
structural genes and expression thereof in transformed microbial
host cells
Production of lactic acid by continuous fermentation using an
inexpensive raw material and a simplified method of lactic acid
purification
Transcription in plants and bacteria
Heat stable alkaline proteases produced by a bacillus
Method for quantitative analysis of thyroid hormone
Human soluble immune response suppressor
Method of purifying toxin conjugates using hydrophobic interaction
chromatography
Cloning and expression of Bacillus thuringiensis toxin gene
encoding a protein toxic to beetles of the order Coleoptera
System and method for fragmentation mapping
Protective antibodies to serotypic determinants of flagellar
antigens
Method of treating polymicrobial burn wound sepsis with a
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3413
3414
4,772,487
4,772,547
3415
4,772,548
3416
4,772,549
3417
4,772,550
3418
4,772,551
3419
3420
3421
3422
4,772,552
4,772,553
4,772,554
4,772,555
3423
3424
3425
4,772,556
4,772,557
4,772,558
3426
3427
3428
3429
3430
3431
4,772,561
4,772,572
4,772,584
4,772,585
4,772,749
4,774,056
3432
4,774,073
3433
3434
4,774,086
4,774,087
3435
4,774,088
3436
3437
4,774,173
4,774,174
3438
3439
3440
3441
3442
3443
4,774,175
4,774,176
4,774,177
4,774,178
4,774,179
4,774,180
3444
3445
3446
3447
3448
3449
4,774,182
4,774,183
4,774,184
4,774,185
4,774,186
4,774,187
3450
3451
4,774,192
4,775,619
combination therapy of ciprofloxacin and pseudomonas immune
globulin
Method and apparatus of forming solid phase reagent in micromodule
HTLV-III envelope peptides
Radioisotopicassay using isotope transfer to chelator-target
recognition molecule conjugate
Polymorphisms related to lipid metabolism: ApoB, ApoCII, ApoE,
ApoAIV
Heterogeneous specific binding assay employing an aggregatable
binding reagent
Method and test kit for detecting a trichothecene using novel
monoclonal antibodies
Monoclonal antibody which recognizes a 200-220 KD antigen on
natural killer cells
Method for determination of enzyme activity
Ova fertilization assay
Dedicated ribosomes and their use
Genetically stable allopolyploid somatic fusion product useful in
the production of fuel alcohols
DNA clone of human skin fibroblast collagenase enzyme
Blood culture system
Test device and method of determining concentration of a sample
component
Hybridomas and monoclonal antibodies to human IL-2
Inhibitor of C5a-mediated chemotaxis
Protein thrombolytic agent with absorption enhancing agent
Process for the recovery of malic acid
Apparatus for testing sedimentation rates of liquids
Method of assessing hypothalamus function and anterior pituitary
hormone function
Process for the purification, solubilization and/or detoxification of
protein antigens of bacteria of the Bordetella genus using a
carbonate buffer and an acellular anti-whooping cough vaccine
Micro-size fibrinolytic plasmin
Method and additives for improving the quality and shelf life of
stored blood
Microbiological assay kit and method for detecting de novo
biomolecular synthesis inhibitors
Solid phase system for ligand assay
Immunochemical methods for the detection of antibody against
HTLV-III
Sensitive tests for malignancies based on DNA detection
Immunoassay method for detection of antibodies and antigens
Immobilization of biological material within a polymer matrix
Process for preparing a 7-aminocephalosporanic acid compound
Construction and application of polyproteins
Partially defective foreign gene for conferring immunity on a
biological host
Process for producing fructose
Culture and process for producing antibiotic LL-D42067alpha
Novel superoxide dismutase and process for preparation thereof
Microbial compositions and methods for treating soil
Cell-culture apparatus
A dry reagent delivery system with membrane having porosity
gradient
Polynucleotide determination with selectable cleavage sites
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3452
3453
4,775,620
4,775,621
3454
3455
3456
3457
3458
4,775,622
4,775,623
4,775,624
4,775,625
4,775,626
3459
4,775,627
3460
4,775,628
3461
3462
3463
3464
4,775,630
4,775,631
4,775,632
4,775,635
3465
4,776,904
3466
4,777,036
3467
4,777,127
3468
4,777,128
3469
3470
4,777,129
4,777,130
3471
3472
4,777,131
4,777,132
3473
3474
3475
3476
3477
3478
4,777,133
4,777,134
4,777,135
4,777,136
4,777,137
4,777,138
3479
4,777,240
3480
3481
3482
3483
3484
4,777,241
4,777,242
4,777,245
4,777,250
4,777,267
3485
3486
4,777,269
4,777,597
3487
3488
3489
4,778,653
4,778,749
4,778,750
3490
3491
4,778,751
4,778,752
Cytokeratin tumor markers and assays for their detection
Method of distinguishing invasive E. coli that cause septicemia
Expression, processing and secretion of heterologous protein by
yeast
Process for producing L-arginine
Vectors and compounds for expression of human protein C
Inactivating enveloped viruses with a merocyanine dye
Method and compositions for protecting anerobic microorganisms
Coal desulfurization using bacteria adaptation and bacterial
modification of pyrite surfaces
Petri dish for cultivating bacteria and method of inspecting drug
susceptibility
Transcriptional control element adapted for regulation of gene
expression in animal cells
Method of localizing nucleic acids bound to polyamide supports
Enzymatic treatment of solutions of polysaccharide biopolymers
Rapid assay processor
Multilayer analytical element and method of making, using
ultrasonic or laser energy
Process for the culture of Babesia canis, application to the
preparation of antigenes and vaccines and antigenes and
vaccines against pyroplasmosis
Human retrovirus-related products and methods of diagnosing and
treating conditions associated with said retrovirus
Fluorescence immunoassay involving energy transfer between two
fluorophores
Nucleic acid probe detectable by specific nucleic acid binding
protein
Isolation of mycobacterial a 60 antigen for diagnostic purposes
Method of determining sugar content of tobacco using a discrete
analyzer
Assay for salicylate
Device for quantitative endpoint determination in
immunofluorescence using microfluorophotometry
Inositoltriphosphate
Method for producing butanol by fermentation
Monoclonal antibody reactive with Pseudomonas Aeruginosa
Method and apparatus for microbiological testing of liquids
Scoop wheel fermentation unit
SV40 expression vector containing HBxAg as an expression
marker
Proteinaceous substance showing antitumorous action and its
preparing method
Purification of recombinant tumor necrosis factor
Non-human primate monoclonal antibodies and methods
Chymotrypsin model
1,3-dioxol-2-one derivatives
7-Phenylacetic acid-4-alkyl-coumarinyl amides useful in
fluorometric determination of the activity of hydrolases
Signal processing method in autoradiography
Method for preventing biofouling of surfaces in contact with sea
water
Tissue culture and production in permeable gels
Diagnostic methods for immune function
Method for measuring antigens or antibodies in biological fluids
using ligand labeled antigens or ligand labeled antibodies
Receptors specific for hapten-modified self proteins
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3492
3493
3494
3495
3496
3497
3498
4,778,753
4,778,754
4,778,755
4,778,756
4,778,757
4,778,758
4,778,759
3499
4,778,760
3500
3501
3502
4,778,761
4,778,762
4,778,766
3503
4,778,767
3504
4,778,768
3505
3506
4,778,769
4,778,893
3507
3508
4,780,149
4,780,191
3509
4,780,209
3510
4,780,281
3511
3512
4,780,401
4,780,405
3513
4,780,406
3514
3515
3516
4,780,407
4,780,408
4,780,409
3517
4,780,410
3518
4,780,411
3519
3520
4,780,412
4,780,413
3521
4,780,414
3522
3523
3524
3525
3526
3527
3528
4,780,415
4,780,416
4,780,419
4,780,421
4,780,530
4,781,732
4,781,836
3529
4,781,858
Method of quantitatively measuring an oxidative substance using
triphenyl methane type leuco-pigment as a coloring substance
Reagent for determining the amount of magnesium ions
Immunoassay method
DNA complementary to RNA of human leukemia virus
Method for the determination of substrates or enzyme activities
Device for susceptibility testing of microorganisms
Genetic engineering in cyanobacteria
Thermostable .alpha.-amylase-producing, thermophilic anaerobic
bacteria, thermostable .alpha.-amylase and process for producing
the same
Recombinant plasmid inserted with hepatitis B virus gene, yeast
transformed with said recombinant plasmid, and production of
hepatitis B virus surface antigen
Plasmid
Method of testing for neutrophil function
Solid phase immunoassay using immunoreagents immobilized on
inert synthetic resin surfaces
Method of monitoring the progressive destruction of articular
cartilage in a joint
Methods of electrochemical assay employing a field effect
transistor
Optical indicator 3,4-dihydro-2-quinolones
Method of making and applying beta-limit dextrin containing starch
hydrolysates
L-glutamine sensor
Process for concentrating and separating trypsin inhibitor and
kallidinogenase in human urine
Method for assay of peroxidase enzyme or reducing substrate
activity
Novel monoclonal antibodies to human renin and hybridoma cells,
processes for their preparation and their applications
Carbonic anhydrase inhibitor-tagged nucleic acid probes
Flow cytometric measurement of total DNA and incorporated
halodeoxyuridine
Monoclonal antibodies to legionella, a process for their preparation
and their use in the determination of legionella pneumophila
Antibody for detection and quantification of trifluralin
Thermally induced phase separation immunoassay
Sandwich enzyme immunoassay for PIVKA-II with monoclonal
anti-PIVKA-II antibody
Water-absorbing, essentially water-free membrane for reagent
substrates and methods of preparing the same
Fibrinolytic enzymes produced from established non-cancerous
cell lines
Production of antiviral agents
Method of producing high molecular weight sodium hyallronate by
fermentation of streptococcus
Method of degrading organic products, by-products and scraps in
an anaerobic medium
Microorganism for BBM 928 production
Method of inhibiting glycolysis in blood samples
Cleavable labels for use in binding assays
Novel interferon alphas
Method for cleaning crude gas and apparatus therefore
Method for biomethanation
Cyclodextrin-silica composite and a method for the preparation
thereof
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3530
3531
3532
4,781,890
4,781,922
4,782,015
3533
4,782,016
3534
3535
3536
4,782,017
4,782,018
4,782,019
3537
3538
3539
3540
3541
3542
3543
3544
4,782,020
4,782,021
4,782,022
4,782,023
4,782,024
4,782,025
4,782,026
4,782,045
3545
3546
3547
3548
3549
3550
4,782,137
4,782,143
4,783,330
4,783,399
4,783,400
4,783,401
3551
3552
4,783,402
4,783,403
3553
4,783,404
3554
3555
3556
4,783,405
4,783,406
4,783,407
3557
3558
4,783,408
4,783,409
3559
3560
3561
3562
3563
3564
3565
3566
3567
3568
4,783,410
4,783,411
4,783,412
4,783,413
4,783,414
4,783,415
4,783,419
4,783,420
4,784,737
4,784,940
3569
3570
3571
4,784,941
4,784,942
4,784,943
3572
3573
4,784,944
4,784,945
Multilayer chemical analytical element
Control of parasitic nematode ova with Bacillus sphaericus
Method for determining the presence of malignant cells
Analytical element and method for determination of theophylline by
enzyme inhibition
Analytical element and method for determination of theophylline by
enzyme inhibition
Detection of hydrolyzing enzymes
Enzymatic production of sphingophospholipid derivatives
Process for the continuous enzymatic conversion of alphahydrocarboxylic acids into the corresponding optically active
alpha-aminocarboxylic acids
Method of producing L-serine
Nitrogen fixation regulator genes
Stabilized horseradish peroxidase conjugate composition
Fermentation process and fermenter
Novel microorganism
Collection medium for whole blood
Promoting the proliferation of intestinal bifidobacteria
Synthesis of protein with an identification peptide, and hybrid
polypeptide incorporating same
Starch hydrolyzates and preparation thereof
Monoclonal antibodies to activated platelets
Diagnostic system for the detection of cytomegalovirus
Homogeneous enzyme immunoassay system and method
Viable cell labelling
Production of primary or secondary alcohol derivatives of
phospholipids by the enzymatic technique
Process for producing l-phenylalanine
L-aminoacid oxidase from yeasts of the genus cryptococcus, their
preparation and use
Recombinant DNA expression vectors useful in bacillus and other
host cells
Method and compositions for use in the treatment of fireblight
Growth of hepatitus A virus in vero cells
Method for the preparation of a fungal body and a lipid rich in Ylinolenic acid therefrom
Immobilized enzyme having reversible solubility
Cytotoxic t lymphocyte serine esterase and method for stimulation
and inhibition
Influenza-A virus vaccine from fish cell cultures
Hybrid DNA synthesis of epidermal growth factor
Apparatus for supplying a medium to a reaction chamber
Germination floor systems
Gene coding for signal peptides and utilization thereof
Examining cells by electrophoresis
Immunoassay for carbohydrate antigenic determinant
Electromicroinjection of particles into living cells
Quantitation of cancer procoagulant activity in serum
Expression and diagnostic use of pENV-3 encoded peptides which
are immunologically reactive with antibodies to LAV
Monoclonal antibodies against autoimmune RNA proteins
Ice nucleation immunoassay
Prothrombin time determining reagent and methods of using and
preparing the same
Method for determining lipids
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3574
3575
4,784,946
4,784,947
3576
3577
3578
4,784,948
4,784,949
4,784,950
3579
4,784,951
3580
3581
3582
4,784,952
4,784,953
4,784,954
3583
3584
4,784,955
4,784,956
3585
3586
3587
3588
3589
3590
3591
4,784,957
4,784,990
4,785,077
4,785,080
4,785,086
4,786,297
4,786,589
3592
4,786,590
3593
4,786,591
3594
3595
3596
3597
3598
4,786,592
4,786,593
4,786,594
4,786,595
4,786,596
3599
4,786,597
3600
4,786,598
3601
3602
3603
4,786,599
4,786,600
4,786,601
3604
3605
3606
4,786,603
4,786,679
4,786,718
3607
3608
3609
3610
3611
3612
4,787,963
4,787,988
4,788,038
4,788,056
4,788,057
4,788,058
3613
3614
3615
3616
4,788,059
4,788,135
4,788,136
4,788,137
Method for assaying the gamma-interferon productivity of blood
Flash-photometer for nephelometric determinations
Production of streptococcal m protein immunogens and molecular
probes
Universal dominant selectable marker cassette
Expression of factor VII activity in mammalian cells
Hybrid cell line for producing monoclonal antibody to antigen on
human thymocytes
Conferred susceptibility to lambda phage in non-coliform
procaryotic hosts
Process and microorganism for degrading steroids
Procedure and device for the fusion of cells
Immunogen conjugates and the use thereof in a dihydropyridine
assay
Vector
Process for the promotion of regeneration of plants from tissue
cultures
High molecular weight sodium hyaluronate
Substantially pure cytotoxicity triggering factor
Labeled analytes
Test for Campylobacter
Gas supply and distribution system
Immunoassay utilizing formazan-prelabeled reactants
Diagnostic and therapeutic aspects of receptor-mediated
leukemogenesis
Process for determining the binding capacity of thyroxin-binding
globulin
Neisseria gonorrhoeae lectin useful as a vaccine and diagnostic
marker and means for producing this lectin
Diagnostic method for detection of neural crest disease
Enzyme immunoassay
Analytical element for analysis of an analyte
Method of preparing a test strip for alcohol testing
Method and apparatus for conducting catalytic reactions with
simultaneous product separation and recovery
Process for the biotechnological preparation of poly-d-(-)-3hydroxybutyric acid
Serum-free animal cell culture medium and methods for the
primary culture and production of cell lines using this medium
Autocatalytic replication of recombinant RNA
Tissue culture holder
Method for separating plasma from blood and silanized glass
fibres therefor
Water-in-oil emulsions of amidase
Method of preparing antibodies to characterize oncogenes
Method and means for annealing complementary nucleic acid
molecules at an accelerated rate
Cell harvester
Process for killing cells
Combined vaccine for viral and bacterial infections
Process for the treatment of psoriasis using typhoid vaccine
B. pertussis vaccine production using carbodiimides
Equine strangles vaccine and the method of preparing and using
the same
System for efficient isolation of genes using probes
Diagnostic immunoassay by solid phase separation for digoxin
Detection of activated T-cells
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3617
4,788,138
3618
4,788,139
3619
3620
4,788,140
4,788,141
3621
3622
3623
3624
3625
3626
3627
4,788,142
4,788,143
4,788,144
4,788,145
4,788,146
4,788,147
4,788,148
3628
4,788,149
3629
4,788,155
3630
4,788,211
3631
4,789,434
3632
3633
4,789,436
4,789,478
3634
3635
4,789,545
4,789,550
3636
4,789,601
3637
3638
4,789,628
4,789,629
3639
3640
3641
3642
4,789,630
4,789,631
4,789,632
4,789,633
3643
3644
4,789,634
4,789,635
3645
3646
3647
3648
3649
3650
4,789,636
4,789,639
4,789,658
4,789,663
4,789,702
4,789,742
3651
3652
3653
4,789,804
4,790,936
4,791,054
3654
4,791,055
Method to achieve a linear standard curve in a sandwich
immunoassay
Platelet aggregation reagent, reagent container and method of
determining platelet aggregation in EDTA-anticoagulated blood
Analytical element containing photosensitive compound and filter
layer and method of use
Automatic analyzer for guanase activity
Method of assaying the metabolic activity of cells capable of
endocytosis
Method for determining levels of cell-mediated immunity
Fermentation process for the high level production of swine growth
Process for preparing 1-O-alpha-D-glucopyranosido-D-fructose
Liquid loaded pad for medical applications
Method for producing ethanolamine oxidase
Plasmid with stabilized inheritance
Proteolytic enzyme from blood-sucking nematodes and its uses as
an anticoagulant as a vaccine and as an antithelminic agent
Method and apparatus for measuring the degree of reaction
between a foreign entity and a subject's blood cells
Antifungal compound and AFC complex produced from
actinomadura SCC 1838
Method and apparatus for measuring corrosion current induced by
microbiological activities
Method and apparatus for nondestructive in vivo measurement of
photosynthesis
Conversion of inorganic ions to metal sulfides by microorganisms
Removal of lipid soluble process chemicals from biological
materials by extraction with naturally occurring oils or synthetic
substitutes thereof
Microcapsule composition suitable for cardiovascular injection
Biocompatible polyorganosiloxane composition for cell culture
apparatus
Devices for carrying out ligand/anti-ligand assays, methods of
using such devices and diagnostic reagents and kits incorporating
such devices
Method and device for collecting and testing for fecal occult blood
Ionic compounds containing the cationic meriquinone of a
benzidine
Immunoassay for anti-dirofilaria immitis antibody
Process for growing granulosis viruses
Fused liposome and acid induced method for liposome fusion
Carrier for the cultivation of human and/or animal cells in a
fermenter
Apparatus for detecting micro-organisms
Double-stranded DNA having sequences complementary to a
single-stranded DNA and derived from mungbean yellow mosaic
virus
Liquid recovery device
Immunoprophylactic and immunotherapeutic agents
Methods of bone repair using collagen
Feline leukemia virus vaccine
Isomaleimide and isophthalimide derivatives of chromophors
Analytical device and method utilizing a piezoelectric crystal
biosensor
Collapsable oil spillage recovery system
Heat exchanger and blood oxygenating device furnished therewith
Homogenous specific binding assay reagent system and labeled
conjugates
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3655
3656
3657
3658
3659
3660
3661
3662
3663
4,791,056
4,791,057
4,791,058
4,791,059
4,791,060
4,791,061
4,791,062
4,791,063
4,791,064
3664
4,791,066
3665
3666
4,791,068
4,792,415
3667
3668
3669
4,792,418
4,792,446
4,792,519
3670
4,792,520
3671
3672
3673
3674
3675
4,792,521
4,792,522
4,792,523
4,792,524
4,792,525
3676
3677
3678
3679
4,792,528
4,792,545
4,792,601
4,792,602
3680
3681
3682
3683
3684
4,793,945
4,793,995
4,793,996
4,794,073
4,794,074
3685
4,794,075
3686
4,794,076
3687
3688
4,794,077
4,794,078
3689
3690
3691
3692
3693
3694
3695
4,794,079
4,794,080
4,794,081
4,794,082
4,794,083
4,794,084
4,794,090
3696
3697
3698
3699
4,794,171
4,794,175
4,794,650
4,795,459
Calibration device for heterogeneous immunoassay
Highly sensitive enzymatic assay method
Grape pomace as substrate for microbial production of citric acid
Process for preparing lipase
Device for performing qualitative enzyme immunoassays
Immobilization of microorganisms by entrapment
FVR vaccine
Polyionene transformed modified polysaccharide supports
Plasmids from nocardia
Immunoelectrophoresis method for diagnosing and differentiating
cancer using lectins
Diagnostic assay for inhibitor of tissue-type and urokinase-type
plasminogen activators
Quaternary ammonium salts of anionic gums
Method of extraction and purification of polyunsaturated fatty acids
from natural sources
Production of antibody catalysts
Method for the monitoring and control of microbial populations
Methods and kits for identifying mutagenic agents and molecular
mutations in DNA in mammalian cells
Non-enzymatic immunohistochemical staining system and
reagents
Rigolettone antitumor complex
3'Expression enhancing fragments and method
Adult T cell leukemia associated cell strain
Tetrapeptide
Methods for obtaining monoclonal antibodies useful in enhanced
sensitivity immunoassays
Boholmycin antibiotic
Monoclonal antibody to mullerian inhibiting substance
Adaptors, and synthesis and cloning of proinsulin genes
Use of inositol triphosphate as a stabilizer and compositions
formed therefrom
Modified (1-56) beta interferons
Method of making soybean extract inhibitor
Detection of nucleic acid hybrids by prolonged chemiluminescence
Method and kit for detecting human exposure to genotoxic agents
Method for locating and purifying DNA containing single base
mismatches
Simultaneous extraction of a ligand from a sample and capture by
anti-ligands therefor in ligand/anti-ligand assays
Detection of human cancer cells with anitbodies to human cancer
nucleolar antigen p145
Alpha amylase assay
Determination of hydrogen peroxide using fluorogenic
dihydroquinolone and dihydrocoumarin indicators
Microbial co-culture production of propionic acid
Process for the preparation of riboflavin
Biotinylating agents
Process for immobilization of glucoamylase
Acyl-CoA synthetase
Immobilization support for biologicals
Calcium-phosphate type hydroxyapatite and process for producing
same
Glucoamylase CDNA
Electronic tuning receiver
Implantable prosthetic device with lectin linked endothelial cells
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3700
3701
3702
3703
3704
4,795,542
4,795,633
4,795,698
4,795,699
4,795,700
3705
3706
3707
3708
4,795,701
4,795,702
4,795,703
4,795,704
3709
3710
4,795,705
4,795,706
3711
3712
3713
3714
4,795,707
4,795,708
4,795,709
4,795,711
3715
3716
3717
3718
3719
4,795,803
4,795,805
4,795,809
4,795,822
4,795,855
3720
3721
3722
4,797,181
4,797,254
4,797,259
3723
3724
4,797,276
4,797,277
3725
3726
3727
4,797,278
4,797,279
4,797,355
3728
4,797,356
3729
4,797,357
3730
4,797,358
3731
3732
3733
3734
3735
4,797,359
4,797,360
4,797,361
4,797,362
4,797,363
3736
3737
3738
3739
3740
4,797,364
4,797,365
4,797,366
4,797,367
4,797,368
3741
3742
3743
4,797,370
4,797,390
4,797,473
Electrochemical concentration detector device
Vaccine for swine trichinosis
Magnetic-polymer particles
T7 DNA polymerase
Nucleic acid probes and methods of using same
Homogeneous polynucleotide displacement assay method kit and
reagent complex
Diagnostic method for gonorrhea by assay of IgA1 fragments
Heparin assay
Multiphase asymmetric membrane reactor systems
Methods of producing herbicide resistant plant varieties and plants
produced thereby
Novel expression control sequences
Electrochemical sensor having three layer membrane containing
immobilized enzymes
Novel backteria and single cell protein production therewith
Solvent-induced autolysis of cells
Fermentation of organic materials for producing heat and fertilizer
Adhesin antigens, antibodies and DNA fragment encoding the
antigen, methods and means for diagnosis and immunization etc.
Derivative of adult T cell leukemia virus antigen peptide
Novel clavam derivatives and methods of making same
Nortriptyline conjugates to antigenic proteins and enzymes
Transformation and foreign gene expression with woody species
Flavin cofactor modified electrodes and methods of synthesis and
use
Protection means for a process analyzer system
Well-type diagnostic plate device
Control of cotton boll weevil, alfalfa weevil, and corn rootworm via
contact with a strain of Bacillus thuringiensis
Method for reperfusion therapy
Hypocholesterolemically and/or hypotriglyceridemically active
products and their use
Insecticidal hybrid bacteria from b.t. kurstaki and b.t. tenebrionis
Methods for attaching polynucleotides to supports
Monoclonal antibodies specific to glactosyltransferase isoenzyme
II and their use in cancer immunoassays
Light-stable reducible compounds and analytical compositions,
elements and methods utilizing same
Microorganism or enzyme immobilization with a mixture of alginate
and silica sol
Heat shock regulated production of selected and fused proteins in
yeast
Conversion of sucrose to fructose and ethanol
Microorganism and process
Alkaline proteases and microorganisms producing same
Bacteriophages as recognition and identification agents
Process for preparing concentrated amounts of lyophilized
microorganisms
Active dried yeast
Gas treatment and resin regeneration process
Aerobic composting apparatus
Adeno-associated virus as eukaryotic expression vector
Antibody preparation with specificity for 4-(2-Aminoethyl) Imidazoyl
group manufacture and use of the antibody preparation
Inositol triphosphate pharmaceutical compositions
Monoclonal antibodies to unreduced, nonenzymatically-glycated
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3744
3745
4,797,476
4,798,706
3746
3747
3748
4,798,723
4,798,786
4,798,787
3749
4,798,788
3750
4,798,789
3751
3752
3753
3754
3755
3756
4,798,790
4,798,791
4,798,792
4,798,793
4,798,795
4,798,796
3757
3758
4,798,797
4,798,798
3759
4,798,799
3760
4,798,800
3761
4,798,801
3762
4,798,802
3763
3764
3765
4,798,807
4,798,824
4,798,886
3766
3767
4,799,361
4,799,545
3768
3769
3770
3771
4,800,155
4,800,156
4,800,157
4,800,158
3772
4,800,159
3773
3774
4,800,160
4,800,161
3775
3776
4,800,162
4,800,163
3777
3778
4,800,164
4,800,169
3779
4,800,959
3780
3781
4,801,299
4,801,451
proteins
Mono-4-arylazoaryl phosphoric esters
Device for holding horizontal array of liquid aliquots
Agricultural products from Pseudomonas cepacia strains and
methods of preparation
Living cells encapsulated in crosslinked protein
Peptide antibodies and their use in detecting oncogene products
Processes and materials for carrying out microchemical and
microbiological tests
cDNA clones coding for polypeptides exhibiting murine interleukin2 activity
Monoclonal antibody specific for a pigmentation associated
antigen
Vector for high level gene expression
Bacterial hydroxylation of codeine
Immobilized Mucor miehei lipase for transesterification
Biotinylating agents
Cell lines and their use for the production plasminogen activators
Retrovirus associated with lymphadenopathies and adapted to
continuous lines of lymphoblastoid B cells, capable of producing
retrovirus continuously and process for their production
Apparatus for monitoring a chemical process
Process for producing diol and furan and microorganism capable
of same
Process for isolating human globular domain NC1 of basal
membrane collagen from human tissue
Production of methane by anaerobic fermentation of waste
materials
Method for accelerating composting of organic matter and
composting reactor therefor
Monoclonal antibodies and method for detecting dioxins and
dibenzofurans
Perfusate for the preservation of organs
Mutual separation of proteins
Method for cryopreparing biological tissue for ultrastructural
analysis
Bacteria and its use in a microbial profile modification process
Human monoclonal antibody to lung carcinoma and hybridoma
producing the same
Anaerobic germiculture receptacle
Process for producing the A-21978C antibiotics
Bacterial method and compositions for linalool degradation
Process for amplifying, detecting, and/or cloning nucleic acid
sequences
Process and apparatus for producing immobilized enzyme
granules
Process for the microbiological preparation of aldose-1-epimerase
Method for resolution of steroisomers in multiphase and extractive
membrane reactors
Flow chamber and electro-manipulator incorporating same
Automatic device for the analysis and cloning of cellular cultures
as well as for bacteriological analysis
Test aids and method for the preparation thereof
Microbial process for selectively plugging a subterranean
formation
Body implants of extracellular matrix and means and methods of
making and using such implants
Cleaning with enzymes from krill
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3782
4,801,463
3783
3784
3785
3786
4,801,529
4,801,530
4,801,531
4,801,532
3787
3788
3789
3790
3791
3792
3793
3794
4,801,533
4,801,534
4,801,535
4,801,536
4,801,537
4,801,538
4,801,539
4,801,540
3795
3796
3797
4,801,541
4,801,542
4,801,543
3798
3799
3800
3801
4,801,544
4,801,545
4,801,546
4,801,547
3802
3803
4,801,548
4,801,576
3804
3805
3806
3807
4,801,621
4,801,685
4,801,686
4,801,690
3808
3809
4,801,691
4,801,697
3810
4,802,101
3811
3812
3813
3814
3815
4,803,073
4,803,074
4,803,153
4,803,154
4,803,155
3816
4,803,156
3817
4,803,157
3818
4,803,158
3819
4,803,159
3820
4,803,160
3821
3822
4,803,161
4,803,162
Continuous cheese-making process utilizing an immobilized
rennet enzyme reactor
Methods for isolating mutant microoganisms using microcapsules
coated with indicator material
Nucleotide hybridization assay for protozoan parasites
Apo AI/CIII genomic polymorphisms predictive of atherosclerosis
Immunological methods for diagnosing neurocysticercosis
Method of using alpha-1 acid glycoprotein on T-cells as a marker
for alzheimer's disease
Water soluble zanthylium derivative substrates
Method for detection of periodontal disease
Method for producing heterologous proteins
Vector for expression of polypeptides in bacilli
Process for determining superoxide dismutase activity
Fermentation method for producing hyaluronic acid
PG gene and its use in plants
Method of increasing the yield of a product by altering a
microorganism
Expression of biologically active PDGF analogs in eucaryotic cells
Process and device for the differentiation of particles in a medium
Method of improving the storage life of liquid compositions
containing enzymes
Enhanced somatic embryogenesis using maltose
Apparatus for detecting micro-organisms
Device for detecting presence of micro-organisms in a sample
Petri dish for cultivating bacteria and method of inspecting drug
susceptibility
Method of inhibiting blood clotting with desulfatohirudins
Foam-containing polyurethane(urea) compositions and process for
the preparation thereof
Microbial production of mature human leukocyte interferon K and L
Purification of recombinant interleukin-1
Novel lectins derived from bacterial pili
Method for removing sodium dodecyl sulfate from sodium dodecyl
sulfate solubilized protein solutions
Physiologically active substance TPI and production thereof
Signal processing method for determining base sequence of
nucleic acid
Process for the pasteurization of plasma proteins and plasma
protein fractions
FR-900848 substance and preparation thereof
Process for separating blood serum from blood
Multi-spot enzyme immunoassay method
Monoclonal antibodies to Sclerotinia homoeocarpa
Peptide-beta-lactamase conjugates for enzyme-linked
immunoassays
Hydrolyzable fluorescent substrates for phosphatases and
analytical use thereof
Composition used for the determination of beta-hydroxybutyric
acid and a method for preparing the said composition
Analytical element and method for determination of total lacate
dehydrogenase
Use of polymeric mordants to increase the intensity of rigid
fluorescent dyes
Biological and analytical uses of phenalenone and
benzphenalenone compounds
Composition, article and process for detecting a microorganism
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3823
3824
3825
3826
3827
3828
3829
4,803,163
4,803,164
4,803,165
4,803,166
4,803,167
4,803,168
4,803,169
3830
3831
3832
3833
3834
3835
3836
3837
3838
3839
3840
4,803,171
4,803,217
4,803,224
4,803,998
4,804,381
4,804,382
4,804,450
4,804,469
4,804,518
4,804,534
4,804,537
3841
3842
3843
4,804,545
4,804,624
4,804,625
3844
3845
3846
4,804,626
4,804,627
4,804,628
3847
4,804,629
3848
3849
4,804,676
4,806,148
3850
4,806,311
3851
4,806,312
3852
3853
3854
3855
3856
3857
4,806,316
4,806,336
4,806,343
4,806,346
4,806,347
4,806,355
3858
4,806,415
3859
4,806,423
3860
3861
4,806,426
4,806,463
3862
4,806,464
3863
4,806,465
3864
4,806,466
Preparation of a protein fraction exhibiting cell growth-inhibiting
activity
Preparation of hepatitis b surface antigen in yeast
Nif promoter of fast-growing rhizobium japonicum
Microorganism for degrading toxic waste materials
Monoclonal antidigoxtin antibodies
Microencapsulation with polymers
Assay for human breast cancer
Reagent paper for immunologically analysis, a process for the
preparation thereof and the use thereof
Hapalindolinone compounds as vassopressin antagonists
Antiviral antibiotic complex
Swab retaining vial cap and method of use
Artificial vessel
Artificial vessel
Apparatus for fusing cells
Flexible jacket membrane processing apparatus
Device for occult blood testing
Antibiotic A 42867 and the addition salts thereof
Sperm selection process using a salt of hyaluronic acid
Production of beta-glucan, bran, protein, oil and maltose syrup
from waxy barley
Passive agglutination assay for pseudorabies antibody
Assay procedures
Immunometric assay for the detection of human chorionic
gonadotropin
Method for cloning lymphoblastoid cells
Hollow fiber cell culture device and method of operation
Detoxification of chlorinated aromatic compounds by organism
NRRL B-18087
Enkephalinase B inhibitors, their preparation, and pharmaceutical
compositions containing the same
Apparatus for biological treatment of waste gases
Multizone analytical element having labeled reagent concentration
zone
Multizone analytical element having detectable signal
concentrating zone
Disposable device for use in chemical, immunochemical and
microorganism analysis
Human intestinal hormone and its use
Cryogenic protectant for proteins
Method for isolation of antigen specific immunoglobulin
Interferon combinations
Microencapsulation of living tissue and cells
Method and system for determining the presence of adenosine
triphosphate or flavin mononucleotide
Agents and process for the detection of esterolytic and/or
proteolytic enzymes
Mutant microorganisms containing recombinant DNA and their use
in the production of amylases
Inhibition of HTLV-III by exogenous oligonucleotides
Nuclear binding assay for steroid receptor functionality in
cancerous cells
Cytoplasmic antigens of candida albicans and methods of using
the same
Cell agglutination reagent comprising conjugates of antibody
covalently bound to liposomes
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3865
3866
3867
4,806,467
4,806,468
4,806,469
3868
3869
4,806,470
4,806,471
3870
3871
4,806,472
4,806,473
3872
3873
3874
4,806,474
4,806,475
4,806,476
3875
3876
4,806,477
4,806,478
3877
4,806,479
3878
3879
3880
3881
3882
3883
3884
3885
4,806,480
4,806,481
4,806,482
4,806,483
4,806,484
4,806,488
4,806,546
4,806,626
3886
3887
3888
3889
4,806,627
4,806,628
4,806,631
4,806,636
3890
4,806,650
3891
3892
3893
3894
3895
3896
3897
3898
3899
3900
4,808,151
4,808,379
4,808,404
4,808,405
4,808,517
4,808,518
4,808,519
4,808,520
4,808,521
4,808,522
3901
4,808,523
3902
3903
4,808,524
4,808,525
3904
4,808,526
3905
4,808,527
Method for the detection of equine infectious anemia and other
retrovirus infections using a competitive enzyme-linked
immunoabsorbent assay and reagents useful in the same
Measurement of glycosylated hemoglobin by immunoassay
Process for the determination of lipase activity
Analytical element and method for theophylline determination
having increased alkaline phosphatase isoenzyme
Plasmids with conditional uncontrolled replication behavior
Cloning and expression vector, yeast transformed by such vector
and applications thereof
Process for enzymatic production of peptides
Preparation of mycelial chitosan and glucan fractions from
microbial biomass
Alkaline peroxide treatment of agricultural byproducts
Efficient cell fusion process
Process for reacting substrates with biocatalysts in a 2-phase
liquid system
Dry enzyme formulations containing D-amino acid oxidase
Use of stabilizing agents in culture media for growing acid
producing bacteria
Novel E. coli hybrid plasmid vector conferring sucrose fermenting
capacity
Streptococcus sojalactis
Microbial degradation of hydrocarbons
Process for regenerating corn
Perfusion airlift bioreactor
Ligand-receptor assays employing squarate dye compositions
Immobilization of nucleic acids on derivatized nylon supports
.alpha.-amylase inhibitor
Hybrid cell lines producing monoclonal antibodies dircted against
scrapie-associated fibril proteins
Monoclonal antibodies against melanocytes
Immobilization of nucleic acids on solvolyzed nylon supports
Heteropolysaccharide produced by Enterobacter sakazakii
Process for preparing 1-deoxynojirimycin and N-derivatives
thereof
Simplified method for the preparation of human lymphokine
activated killer cells
Device for obtaining stool samples and detecting occult blood
Live vaccine for coccidiosis utilizing coccidial sporozoites
P-anisoyl streptokinase/plasminogen complex
Bioassay for toxic substances
Recovery of cytomegalovirus antigen and use thereof in an assay
Method of detecting nucleic acid sequences
Labelling of oligonucleotides
Double-labeled enzymeimmunoassay methods
Enzyme immunoassays using inorganic pyrophosphatase
Constitutive production of human IFN-.beta.1 by mammalian cells
transformed by the IFN-.beta.1 gene fused to an SV40 early
promoter
Test kit and method for the determination of Streptococcus A
antigen
Site specific cleavage of DNA
Continuous process for ethanol production by bacterial
fermentation
Continuous process for ethanol production by bacterial
fermentation
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3906
3907
4,808,528
4,808,529
3908
3909
3910
3911
4,808,530
4,808,531
4,808,532
4,808,533
3912
4,808,534
3913
4,808,535
3914
4,808,536
3915
4,808,537
3916
4,808,541
3917
3918
4,808,700
4,808,702
3919
3920
3921
4,808,704
4,808,707
4,810,381
3922
4,810,394
3923
3924
4,810,413
4,810,414
3925
4,810,487
3926
3927
3928
4,810,493
4,810,494
4,810,495
3929
4,810,629
3930
4,810,630
3931
3932
3933
3934
4,810,631
4,810,632
4,810,633
4,810,634
3935
3936
4,810,635
4,810,636
3937
3938
3939
3940
4,810,638
4,810,639
4,810,640
4,810,641
3941
4,810,642
Antibody composition for the detection of malignant cells with
metastatic cell activity
Enzymes immobilized on polyamides or cellulose hydrate
Protein immobilization by adsorption of a hydrophobic amidine
protein derivative to a hydrophobic surface
New restriction enzyme and process for producing the same
Continuous human cell lines and method of making same
Method of preventing T-cell blastogenesis
Method and apparatus for the microbiological production of singlecell protein
Acinetobacter species and its use in removing organic sulfur
compounds
Immunochemical method for detection of antibody against HTLVIII core protein based upon recombinant HTLV-III gag gene
encoded protein
Methanol inducible genes obtained from pichia and methods of
use
Determination method utilizing reagents covalently labelled with
essentially non-fluorescent lanthanide chelates in combination with
time-resolved fluorescence spectroscopy and the reagents to be
used in the method
Immunogenic conjugates of non-toxic E. coli LT-B enterotoxin
subunit and capsular polymers
Decapeptides produced from bioadhesive polyphenolic proteins
Monoclonal antibodies to cell surface antigens of human malignant
melanoma
Chitosan alginate capsules
Composite chromatographic article
Process and apparatus for removing solid material including blood
cells from whole blood
Particles containing ammonium salts or other chlorine scavengers
for detergent compositions
Enzymatic detergent additive
Method of identifying polymethine stained lymphocyte
subpopulations and compositions thereof
Method for the culture of the TRT/SHS virus, and vaccine
therefrom, especially for the treatment of turkeys
Canine parvovirus vaccines
Agent for inhibiting proliferation of human malignant tumor cells
Identification of viral associated immunoreactants in biological
fluids
Use of polyoxyethylene ethers to improve the performance of
immunoassays employing peroxidase conjugates
Signal enhancement in immunoassay by modulation of chemical
catalysis
Cell surface antigen detection method
Enzymatic ethanol test
Pseudorabies virus mutants incapable of producing glycoprotein X
Specific binding assays employing label analog to reduce sample
interferences
Chromogenic acridinone enzyme substrates
Enzyme-labeled antibody reagent with polyalkyleneglycol linking
group
Immunoassay for CK-MB using bound and soluble antibodies
Method of quantitative assay for 1,5-anhydroglucitol
Biochemical assays
Method and test composition for determination of hydrogen
peroxide
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3942
4,810,643
3943
3944
3945
4,810,644
4,810,645
4,810,646
3946
4,810,647
3947
4,810,648
3948
3949
3950
3951
3952
3953
3954
3955
4,810,649
4,810,650
4,810,651
4,810,652
4,810,653
4,810,781
4,811,218
4,812,220
3956
3957
3958
4,812,310
4,812,392
4,812,393
3959
3960
3961
3962
4,812,394
4,812,395
4,812,396
4,812,397
3963
4,812,398
3964
3965
4,812,399
4,812,400
3966
3967
4,812,401
4,812,402
3968
3969
4,812,403
4,812,404
3970
3971
4,812,405
4,812,406
3972
3973
4,812,407
4,812,408
3974
4,812,409
3975
4,812,410
3976
4,812,411
3977
3978
3979
3980
3981
3982
4,812,414
4,812,441
4,812,557
4,812,559
4,813,424
4,813,432
Production of pluripotent granulocyte colony-stimulating factor
Probe and a process for the detection of specific microorganisms,
particularly legionellas, in environments which contain them
Microbial production of mature human leukocyte interferon K and L
Glucan compositions and process for preparation thereof
Process of producing ethanol and various other by-products from
cereals
Haloarylnitrile degrading gene, its use, and cells containing the
gene
Controlled regeneration of zea diploperennis hybrids and breeding
strategies therewith
Determination of biomass
Blood culture assembly with an externally actuated valve
Cell growth harvester for roller bottles
Cuvette with non-flexing thermally conductive wall
Methods of preparing epitopes of tumor associated antigens
Real time scanning electrophoresis apparatus for DNA sequencing
Enzyme sensor for determining a concentration of glutamate
Preserving solution for blood or packed blood cells and method for
preserving blood or packed blood cells by using the same
Method and apparatus for incubating cells
Fluorescent dyes and biological and analytical uses thereof
Flow cytomeric measurement of DNA and incorporated nucleoside
analogs
Method for detecting enzymatic activity using particle agglutination
Method for detecting enzymatic activity using particle agglutination
MAB-anti-DNA related to nephritis
Reagent for measuring amylase activity and measuring method
thereof
Analytical element and method for the determination of creatinine
or creatine
Process for measuring sodium levels in biological fluids
Reversible agglutination mediators for separating cells from whole
blood
Method of determining hypersensitivity to an allergen
Optically active substituted butyramide, and process for the optical
separation of substituted butyramide
Apatite immobilized glucanase
Double auxotrophic mutants of Pichia pastoris and methods for
preparation
Process for preparing optically active hydantoins
Membrane, system and process for testing substance diffusion
through the membrane and method for making the membrane
Blood culture system
Hydrolyzable fluorescent substrates and analytical determinations
using same
Continuous process for ethanol production by bacterial
fermentation
Method of performing medical analyses, and a conditioning strip
and apparatus for performing the method
Immunoreactive reagent particles having tracer, receptor
molecules and protein of pI less than 6
Hypocholesterolemically active protein derived from streptococcus
Stable composition of interleukin-2 and human serum albumin
Vaccine against varicella-zoster virus
Long-life membrane electrode for non-ionic species
Swab transport system
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3983
4,814,169
3984
4,814,247
3985
4,814,267
3986
3987
3988
3989
4,814,268
4,814,269
4,814,270
4,814,271
3990
3991
3992
4,814,272
4,814,273
4,814,274
3993
3994
3995
3996
3997
3998
3999
4000
4001
4,814,275
4,814,276
4,814,277
4,814,278
4,814,279
4,814,324
4,814,433
4,814,434
4,815,978
4002
4003
4,816,077
4,816,168
4004
4005
4006
4,816,244
4,816,249
4,816,250
4007
4,816,253
4008
4009
4,816,387
4,816,388
4010
4,816,389
4011
4012
4,816,390
4,816,391
4013
4,816,392
4014
4,816,393
4015
4016
4,816,394
4,816,395
4017
4,816,396
4018
4019
4,816,397
4,816,398
4020
4,816,399
4021
4,816,400
Process for the production of anti-human protein antibody
Method for determining the existance and/or the monitoring of a
pathological condition in a mammal
Method for preparing high conversion syrups and other
sweeteners
Methods for propagating fastidious human viruses and for
producing purified suspensions thereof
Diagnostic testing for antibodies against microorganisms
Production of loaded vesicles
Method for detecting esterolytic and proteolytic enzymes
Process for the biotechnical production of rhamnolipids including
rhamnolipids with only one .beta.-hydroxydecanoic acid residue in
the molecule
Production of organic acids by an improved fermentation process
Production process of encapsulated bodies
Monoclonal hybridoma antibody specific for a human epithelial
antigen
Selective medium for growth of neisseria
Method of inactivating reproductive filterable pathogens
Culture apparatus and method
Incubator for chemical-analytical slide
Sterol inhibitors of testosterone 5.alpha.-reductase
Method for obtaining a papain-free antibody fragment preparation
Inducer of T-suppressor cells
Clinical analysis methods and systems
Process for the preparation of an aqueous solution of a
heteropolysaccharide
Separation of lymphocytes and monocytes from blood samples
Stabilized stain solutions containing aliphatic and aromatic
alcohols
Monoclonal anti-idiotype antibodies
Preparing vaccine against Herpes simplex virus
Novel mutant strain of Listeria monocytogenes and its use in
production of IgM antibodies and as an immunotherapeutic agent
Method for detection of antibodies to HTLV-III and diagnostic test
kit useful therewith
Human prealbumin and related methods and products
Probe for DNA and a process for the detection of "shigellae" and
entero-invasive strains of Escherichia coli
Immunochemical assay of carcinoembryonic antigen and reagent
therefor
Amine stabilized aminoglycoside formulations
Rapid stick test for detection of ciguatoxin and other polyether
toxins from tissues
Nucleoside triphosphate-dependent 1-methylhydantoinase, a
process for obtaining it and the use thereof
Quantitative analysis of 3.alpha.-hydroxysteroid and reagent
useful therefor
Method for predicting chemosensitivity of anti-cancer drugs
Method and vector organism for controlled accumulation of
heterologous gene products in bacillus subtilis
Multichain polypeptides or proteins and processes for their
production
Casein phosphopeptide composition
Continuous process for ethanol production by bacterial
fermentation
Basement membrane collagen degrading enzyme and method of
purifying same
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4022
4023
4,816,401
4,816,402
4024
4,816,403
4025
4026
4027
4028
4,816,404
4,816,405
4,816,406
4,816,409
4029
4,816,411
4030
4031
4,816,419
4,816,559
4032
4033
4034
4035
4036
4,816,563
4,816,565
4,816,566
4,816,567
4,818,268
4037
4038
4039
4040
4041
4042
4043
4,818,406
4,818,516
4,818,528
4,818,623
4,818,677
4,818,678
4,818,679
4044
4045
4046
4047
4,818,680
4,818,681
4,818,682
4,818,683
4048
4049
4,818,684
4,818,685
4050
4051
4,818,686
4,818,688
4052
4053
4,818,689
4,818,690
4054
4,818,691
4055
4,818,692
4056
4057
4058
4059
4,818,693
4,818,694
4,818,695
4,818,696
4060
4061
4062
4063
4,818,697
4,818,698
4,818,699
4,818,700
Serum free cell culture medium
Murine hybridoma and diagnostic antibody produced thereby
Detoxification of chlorinated aromatic compounds by organism
NRRL B-18086
Late differentiation antigens associated with helper T lymphocyte
function
Vectors for transformation by ascomycetes
Inhibition of trichothecene toxins by ancymidol
Method of eliminating tumor cells and device therefor
Method for eliminating turbidity in a biological fluid and reagent
therefor
Fluorescence ligand binding assay using charge-matched dye and
solvent components
Biologically active peptides TAN-866
Process for obtaining transfer factor from colostrum, transfer factor
so obtained and use thereof
Interleukin 2 receptor and a method for production thereof
Polypeptides having interferon activity
Recombinant immunoglobin preparations
Osmoprotectant
Biological degradation of chemicals bearing an oxydibenzene
nucleus
Method of nutritional assessment and therapy
Vaccine against infectious bovine keratoconjunctivitis
Slide glass
Membrane assay using focused sample application
Diagnostic system for the detection of cytomegalovirus
Method for recovering mutant cells
Method and kit involving displacement and rehybridization of
labeled polynucleotide
Fast and specific immobilization of nucleic acids to solid supports
In vitro detection of gastrointestinal cancer
Immunoassay for monoamines
Auto-anti-idiotypic monoclonal antibodies to steroid receptors and
uses thereof
Method and kit for diagnosing bloom's syndrome
Chemical blocking agent against non-specific binding or staining of
an antibody specific for terminal deoxynucleotidyl transferase in
biological specimens during immunoassay
Assays for antibody to hepatitis B core antigen
Late differentiation antigen associated with helper T lymphocyte
function
Method for the determination of plasminogen activators (PA)
Colormetric method for quantification of magnesium using .alpha.glycerophosphate oxidase
Method and reagent compositions for determining alpha amylase
using a blocked and labeled substrate
Methods and materials for enhanced somatic embryo regeneration
in the presence of auxin
Production of herpes simplex viral protein
Immobilized Mucor miehe lipase for transesterification
Rhizobium japonicum symbiosis gene transfer
Techniques for enhancing the permeability of ions through
membranes
Polypeptides and preparation process thereof
Generation of somaclonal non-mendelian variants
Pichia pastoris argininosuccinate lyase gene and uses thereof
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4064
4065
4066
4067
4068
4,818,702
4,818,709
4,818,817
4,820,292
4,820,399
4069
4070
4071
4072
4073
4,820,416
4,820,489
4,820,504
4,820,505
4,820,514
4074
4075
4,820,515
4,820,516
4076
4,820,520
4077
4078
4,820,626
4,820,628
4079
4,820,629
4080
4081
4082
4,820,630
4,820,631
4,820,632
4083
4084
4085
4086
4,820,633
4,820,634
4,820,635
4,820,636
4087
4088
4089
4090
4,820,637
4,820,638
4,820,639
4,820,640
4091
4092
4093
4094
4,820,641
4,820,642
4,820,646
4,820,689
4095
4096
4,820,692
4,820,811
4097
4,822,470
4098
4099
4100
4,822,490
4,822,516
4,822,534
4101
4,822,566
4102
4103
4104
4,822,731
4,822,732
4,822,733
4105
4,822,734
Fecal occult blood test reagent
CEA-family antigens, Anti-CEA antibodies and CEA immunoassay
Enzymatic degradation of lipopolysaccharide bioemulsifiers
Anti-microbial sensitivity test and testing stratum
Enzyme electrodes
Removal of bilirubin by the pseudoperoxidase activity of
immobilized hemoglobin
Test strips and a process for the production thereof
Multi-specimen tissue blocks and slides
Detection of activated platelets with antibodies to thrombospondin
Low dosage of interferon to enhance vaccine efficiency
Method of using interferon in low dosage to regulate appetite and
efficiency of food utilization
Hyaluronidase
Antiseptic agent for food and drink and method of antiseptic
treatment thereof
Method of treating a synthetic or naturally occuring surface with
microvascular endothelial cells, and the treated surface itself
Fetal lung maturity test employing lamellar body solubilization
Immunoassay for antibodies to pseudorabies virus using mediumelaborated viral antigenic factor
Assay for nucleic acid sequences, particularly genetic lesions,
using interactive labels
Deletion mutants and monoclonal antibodies against ras proteins
Agent and process for the detection of redox systems
Process for production of an immune reactive, porous carrier
material for heterogeneous immunological analysis
Immunoassay method and immunoreactive cell reagent
Kit for assaying activation of terminal complement cascade
Electrochemical assay for cis-diols
Detection of fungi and/or algae with stilbene having at least 4
sulpho groups
Novel alpha interferon species produced by recombinant means
Process for enhancing translational efficiency of eukaryotic mRNA
Method of producing dextranase
Monoclonal antibody capable of specifically distinguishing human
hepato-carcinoma cells
Amplified expression vector
Fecal occult blood test method
Pharmaceutical composition containing a glycoprotein
Methylthioribose analogs, their preparation and use as medicinal
agents and biocides
Amine reacted therapeutic agents
Method of and apparatus for cell poration and cell fusion using
radiofrequency electrical pulses
Bacterial compositon and method for recovery of oil-polluted water
and soil
Detergent composition for clothing incorporating a cellulase
Method of producing microspheres
Optimized capacitive sensor for chemical analysis and
measurement
Process for labeling single-stranded nucleic acids and
hybridizaiton probes
Method of concentrating and detecting biomolecules and cells
Lifetime-resolved assay procedures
Method for improving the elicitation of IgG class monoclonal
antibodies to tumor-associated antigens and glycoproteins
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4106
4,822,735
4107
4108
4109
4,822,736
4,822,737
4,822,738
4110
4,822,739
4111
4,822,740
4112
4113
4,822,741
4,822,742
4114
4115
4,822,746
4,822,879
4116
4117
4,824,432
4,824,529
4118
4,824,571
4119
4120
4121
4,824,639
4,824,640
4,824,666
4122
4,824,667
4123
4,824,668
4124
4,824,671
4125
4,824,775
4126
4127
4,824,776
4,824,777
4128
4,824,778
4129
4130
4,824,779
4,824,780
4131
4,824,781
4132
4,824,782
4133
4134
4135
4136
4137
4138
4139
4,824,783
4,824,784
4,824,785
4,824,786
4,824,787
4,824,788
4,824,863
4140
4141
4,824,938
4,824,941
T cell growth factor and method of making same
Amplification of adenosine deaminase genes in mammalian cells
using adenosine, alanosine, uridine, and deoxycoformycin
Process for producing ethanol by fermentation
Transducible composite plasmid
Partition proficiency in genetically engineered plasmids for
transforming gram-positive organisms
Bacteria for expressing a polysaccharide depolymerase containing
a novel recombinant plasmid
Biocompatible polyorganosiloxane composition for cell culture
apparatus
Reaction tray for membrane hybridizations
Radiative and non-radiative energy transfer and absorbance
modulated fluorescence detection methods and sensors
Enzyme-inhibitory griseolic acid derivatives, and their use
Method for treating AIDS and other immune deficiencies and
immune disorders
Lipid membrane-based device
Method of and equipment for anaerobic degradation of organic
products
Test device and a method for the detection of a component of a
liquid sample
Transparent test strip system
Method of large scale growth of toxoplasmic microorganisms
Thymidine kinase deletion mutants of bovine herpesvirus-1,
vaccines against infectious bovine rhinotracheitis containing same
and methods for the production and use of same
Attenuated infectious bursal disease virus strain and vaccine
therefrom
In vitro method for producing infective bacterial spores and sporecontaining insecticidal compositions
Cells labeled with multiple Fluorophores bound to a nucleic acid
carrier
Method for increasing the sensitivity of nucleic acid hybridization
assays
Method for determining thyroxine uptake
Immunoassay for measuring the concentration of antigen in a
sample
Method for the determination of the reduced form of nicotinamide
adenine dinucleotide
Method for producing hydroquinone
Microbiologically produced d(-)-mandelate-dehydrogenase
process for obtaining it and its use
DNA base sequence, method for preparing a recombinant plasmid
including the DNA base sequence, and breeding method for
enhancing the protein-secreting ability of a microorganism by
introducing thereinto the recombinant plasmid
Oxidized sulfur derivatives of diaminophosphinyl compounds as
urease inhibitors
Chromogenic solution for immunoassay
Canine corona virus vaccine
Methylotroph cloning vehicle
Roller bottle for tissue culture growth
Humidity chamber for immunoperoxidase staining
Antibiotic A80438
Water-soluble dry solid containing proteinaceous bioactive
substance
Specific antibody to the native form of 2'5'-oligonucleotides, the
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4142
4,824,945
4143
4144
4145
4146
4,824,946
4,825,688
4,826,456
4,826,573
4147
4148
4149
4150
4151
4152
4153
4,826,602
4,826,624
4,826,680
4,826,759
4,826,760
4,826,761
4,826,762
4154
4155
4,826,763
4,826,764
4156
4157
4158
4159
4160
4,826,765
4,826,766
4,826,767
4,826,768
4,826,769
4161
4162
4,826,771
4,826,789
4163
4,826,818
4164
4165
4166
4167
4168
4169
4,826,822
4,826,962
4,827,030
4,827,036
4,828,399
4,828,600
4170
4,828,801
4171
4172
4173
4174
4,828,831
4,828,976
4,828,978
4,828,979
4175
4,828,980
4176
4177
4,828,981
4,828,982
4178
4179
4,828,983
4,828,984
4180
4,828,985
4181
4182
4,828,986
4,828,987
method of preparation and the use as reagents in immunoassays
or for binding 2'5'-oligonucleotides in biological systems
Hypocholesterolemically active RNA fractions
Cell culture microcarrier, method for preparing same and use
thereof for cultivating anchorage-dependent cells
Apparatus for sensing of mass in baths
Electrical connector with compliant section
Method for processing substantially solid organic material
Reduction of trace elements to the elemental form by
microorganisms
Dispersing liquid hydrocarbon into a second liquid
Pharmaceutical composition containing thymus extract fractions
Field assay for ligands
Method for determining helper/suppressor cell ratio in blood
Multilayer analytical element for analysis of cholesterol
Enzymatic temperature change indicator
Process for preparing glucagon or fragments or derivatives thereof
in yeast
Enhancing the translational initiation frequency of a gene
Yeast strains genetically engineered to produce wheat gluten
proteins
Production of amino acids using coupled aminotransferases
Enzymatic synthesis of waxes
Polyoxyalkylene glycol conversion to monocarboxylic acid
Biochemically reacting substrates in subterranean cavities
Procedure to be performed in conjunction with protein blotting or
nucleic acid blotting
Porous inorganic materials
Proteinaceous emulsifier, process for preparing same and
emulsion type cosmetic compositions containing same
Liquid suspensions of polyene antibiotics and use thereof for slime
control in industrial waters
Tetrachlororaffinose and its use in the preparation of sucralose
3-hydroxydicarboxylic acids and process for their production
Pseudo-aminosugars, their production and use
Compost handling machine
Biological inoculant for corn
Device for detecting on a nitrocellulose sheet the presence of
macromolecular complexes, such as antigens/antibodies
New conjugates of vinblastine and its derivatives, process for
preparing them and pharmaceutical compositions containing them
Glucose free media for storing blood platelets
Agglutination reagent and method of preparing same
Nucleotide analogs for nucleic acid labeling and detection
Membrane structure coated with low pI protein or carbohydrate
and methods of making and use
Immunoassays for determining Dirofilaria immitis infection using
antiidiotype monoclonal antibody reagents
Vesticles and use thereof in an enzyme assay
Use of phenols and anilines to increase the rate of peroxidase
catalyzed oxidation of leuco dyes
Composition, synthesis and use of simulated cells
Antibodies against the complex of a small molecule and its binding
protein, their preparation and their use in diagnostic methods
Assay method and diagnostic system for determining the ratio of
APO B-100 to APO A-I in a blood sample
Avian retrovirus-bovine growth hormone DNA
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4183
4184
4185
4186
4,828,988
4,828,989
4,828,990
4,828,991
4187
4188
4189
4,828,992
4,828,993
4,828,994
4190
4,828,995
4191
4,828,996
4192
4,828,997
4193
4194
4,828,998
4,828,999
4195
4196
4,829,000
4,829,001
4197
4198
4199
4200
4201
4,829,002
4,829,003
4,829,004
4,829,005
4,829,006
4202
4,829,010
4203
4204
4,829,012
4,829,098
4205
4206
4,830,708
4,830,764
4207
4,830,828
4208
4209
4210
4,830,849
4,830,959
4,830,960
4211
4212
4213
4214
4215
4216
4217
4218
4219
4220
4,830,961
4,830,962
4,830,963
4,830,964
4,830,965
4,830,966
4,830,967
4,830,968
4,830,969
4,830,970
4221
4222
4223
4,831,020
4,831,117
4,831,120
Hybrid polypeptides comprising somatocrinine and alpha.sub.1 antitrypsin, method for their production from bacterial clones and
use thereof for the production of somatocrinine
Process for purifying a protein
Method for purifying an interferon
Tumor specific monoclonal antibodies
Process for the manufacture of an antifungal
antihypercholesterolemic .beta .
Process for the preparation of organic acids
Bacillus strains with reduced extracellular protease levels
Hybrid cell line for producing monoclonal antibody to a human
thymocyte antigen, antibody, and methods
Materials and method for immobilizing biologically active
substances
Apparatus and process for producing gel beads of microbial cells
or enzymes
Bacteriolytic enzyme product from streptomyces, a process for its
preparation, and a strain suitable for this purpose
Bacteriophage prevention and control of harmful plant bacteria
Reconstituted basement membrane complex with biological
activity
Enzymatic neutralization of hydrogen peroxide
System for metering nutrient media to cell culture containers and
method
Pyroelectric enzyme detector
Roller bottle system
Sedimentation filtration microorganism growth culture system
Centrifugation vial and cluster tray
Immunoassay device enclosing matrixes of antibody spots for cell
determinations
Method for immunological assay of antibodies of various types in a
liquid sample
Immobilized biomolecules and method of making same
Direct biological bleaching of hardwood kraft pulp with the fungus
Coriolus versicolor
Polyoxyalkylene-containing phosphoric acid esters
Method for inhibiting sulfide stress corrosion cracking and
hydrogen induced stepwise cracking
Extravascular circulation of oxygenated synthetic nutrients to treat
tissue hypoxic and ischemic disorders
Electrochemical enzymic assay procedures
Determination of chlamydia trachomatis
Method and test kit for analysis of histamine receptor sites of
mammalian cells
Recombinant diphtheria toxin fragments
Production of acetic acid by an improved fermentation process
Ethanol production by high performance bacterial fermentation
Transposable linkers to transfer genetic information
Process for regenerating corn
Process for producing antibiotic A80438
Wine making inoculants and related means and methods
Process for the rapid and simple isolation of nucleic acids
Nutrient substrate carrier
Ingredient effective for activating immunity obtained from Chlorella
minutissima
Monoclonal antibody specific for human B-cells
Method for recovering a purified animal growth hormone or
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4224
4225
4,831,124
4,831,125
4226
4227
4228
4229
4,831,126
4,832,759
4,832,814
4,832,816
4230
4,832,849
4231
4232
4,832,864
4,832,946
4233
4,832,959
4234
4235
4236
4,833,071
4,833,072
4,833,073
4237
4238
4239
4240
4,833,074
4,833,075
4,833,076
4,833,077
4241
4,833,078
4242
4243
4244
4245
4246
4247
4,833,079
4,833,080
4,833,081
4,833,082
4,833,083
4,833,084
4248
4249
4250
4251
4252
4253
4254
4255
4256
4,833,085
4,833,086
4,833,087
4,833,088
4,833,089
4,833,090
4,833,093
4,833,165
4,834,779
4257
4,834,918
4258
4,834,943
4259
4,834,946
4260
4261
4,834,975
4,834,976
4262
4263
4264
4,834,987
4,835,058
4,835,097
polypeptide analog thereof from a bacterial cell
Recombinant cDNA construction method and hybrid nucleotides
useful in cloning
DNA probe for corynebacterium kutscheri
Antigenic polysaccharide specific to Brucella abortus and Yersinia
enterocolitica serotype 0:9
Microstructures
Electrofusion cell and method of making the same
Electrostatic system for treating liquids
Extraction and purification of an anticoagulant principle from the
south american leech, haementeria ghilianii
Compositions and methods that introduce variations in color
density into cellulosic fabrics, particularly indigo dyed denim
Cosmetic composition
Preparation of polypeptides having human .gamma.-interferon
activity
Peptide composition as anitgen for detection of antibodies to
HTLV-I, as a vaccine for ATL and methods therefor
Antigentic peptides and process for their preparation
Immunoassay for tetrahydrocannabinol metabolites
Purified human granylocyte L1 proteins methods for their
preparation, monospecific antibodies and test kits
Immobilized luciferase for the quantitative determination of ATP
Peptide antibiotics
Method for producing human antibody
Semi-continuous fermentation process for aromatic hydrocarbon
bioconversion
Process for producing 3,7-dihydroxytropolone and antitumor use
thereof
Regulation of eucaryotic gene expression
Bioreactor having cells in beads in a matrix
New restriction enzyme and process for producing the same
Packed bed bioreactor
Monoclonal antibody specific for DNA.RNA hybrids
Monoclonal antibody specific for human colon fibroblast-derived tPA
Microbial degradation of hydrocarbons
Disposable container configured to produce uniform signal
Reagent strip handling mechanism
Pressure incubator
Preservation of glucose in blood
Method of silanization of surfaces
Method of inactivating HTLV-III virus in blood
Process for membrane seperation of gas mixtures
Process and reagent for increasing the quantum yield in
chemiluminescent reactions
Apparatus for the preparation of objects for microscopic
examination
Apparatus for blot screening numerous, small volume, antibody
solutions
Human monoclonal antibodies to serotypic lipopolysaccharide
determinants on gram-negative bacteria and their production
Monoclonal antibodies to pseudomonas aeruginosa flagella
Method of preparing food and composition for protecting
microorganisms used in the preparation of food
Packing material and process for its production
Method for ascertaining the history of a condition of the body from
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4265
4,835,098
4266
4,835,099
4267
4268
4269
4,835,100
4,835,101
4,835,102
4270
4,835,103
4271
4,835,104
4272
4,835,105
4273
4,835,256
4274
4275
4276
4,835,258
4,835,260
4,835,262
4277
4278
4,835,263
4,835,339
4279
4280
4,836,855
4,836,918
4281
4282
4283
4284
4285
4286
4287
4288
4,836,928
4,836,987
4,837,016
4,837,018
4,837,022
4,837,028
4,837,043
4,837,144
4289
4290
4,837,145
4,837,146
4291
4,837,147
4292
4,837,148
4293
4294
4295
4296
4,837,149
4,837,150
4,837,151
4,837,152
4297
4,837,153
4298
4299
4300
4,837,154
4,837,155
4,837,156
4301
4,837,162
a single blood sample
Characterization of HLA alleles with locus-specific DNA probes
Signal enhancement in immunoassay by modulation of enzymatic
catalysis
Method and test kit for detecting an aflatoxin B.sub.1 and G.sub.1
using novel monoclonal antibodies
Luminescent analyses with enhanced storage stability
Tissue equivalent test systems
Differential binding of membrane potential sensitive materials to
lymphocytes
Process for producing and purifying 2',3'-dideoxynucleosides, and
process for producing 2',3'-dideoxy-2',3'-didehydronucleosides
Process for the preparation of high-purity gamma- and alphacyclodextrins
Human gamma interferon polypeptide having glutamine as the
ninth n-terminal amino acid
Conjugation of aromatic amines or nitro-containing compounds
with proteins or polypeptides by photoirradiation of the azide
derivatives with ultraviolet light in order to produce antibodies
against the haptens
Erythropoietin composition
Process for preparing pectin
Novel compounds containing an oligonucleotide sequence bonded
to an intercalating agent, a process for their synthesis and their
use
Tomato anther culture
Additive of protein nature for hydraulic cements, mortars &
concretes, and use thereof in the field construction
Apparatus for gas-producing treatment of organic material
Separation method, separation device and separation apparatus
for separating body fluid into respective components
Test tube assembly for serum separation
Protozoal antigen
Vaccines for fowl colibacillosis
Composition containing tissue plasminogen activator
Liposomes with enhanced circulation time
Process for the production of test strips by casting method
Method of measuring lipid-bound sialic acid
Layered immunoassay using antibodies bound to transport
particles to determine the presence of an antigen
Forecasting the risk of sclerotinia stem rot in crops
PhO81 promotor of Saccharomyces cerevisiae and use thereof for
heterologous gene expression
Autonomous replication sequences for yeast strains of the genus
pichia
Novel saframycin A derivatives and process for producing the
same
Oxidation processes
Live vaccines comprising two mutations and foreign antigen
Process for regenerating soybeans
Compost air injection and evacuation system with improved air
control
Selective growth medium for isolation of Mobiluncus from vaginal
fluid
Method of growing trichoderma
Tilting lauter tun
Non-fluorescing, non-reflective polyamide for use in diagnostic
testing
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4302
4303
4,837,167
4,837,169
4304
4305
4306
4307
4,837,170
4,837,171
4,837,189
4,837,304
4308
4309
4310
4311
4,837,306
4,837,313
4,837,361
4,837,373
4312
4313
4314
4315
4316
4317
4,837,390
4,837,395
4,837,399
4,837,733
4,839,017
4,839,046
4318
4319
4320
4,839,142
4,839,169
4,839,194
4321
4322
4,839,275
4,839,276
4323
4,839,277
4324
4,839,278
4325
4326
4327
4328
4329
4,839,279
4,839,280
4,839,281
4,839,282
4,839,283
4330
4331
4332
4,839,284
4,839,285
4,839,286
4333
4,839,287
4334
4,839,288
4335
4,839,289
4336
4,839,290
4337
4338
4,839,291
4,839,292
4339
4340
4,839,293
4,839,296
Immunoassay for multi-determinant antigens using high-affinity
Polypyridine Fluorescent labels for immunoassay
Monoclonal antibody, measuring method of glucosylated protein
by utilizing the monoclonal antibody, and kit therefor
Anti-epiglycanin monoclonal antibodies
Surfactant modified metal catalysts
Inhibitor of ribonucleotide reductase
Method for selecting hybridomas producing antibodies specific to
the P-glycoprotein cell suface antigen and a cDNA clone encoding
the C-terminal portion of the antigen
Polygalactosamine PF-192 and salts thereof
A process for the preparation of cysteine from cystine
Test strips
Hyperbaric organ preservation apparatus and method for
preserving living organs
Single step heterogeneous assay
Napthoquinone antibiotics from fuserium solani
Signal processing method in autoradiography
Potential-causing membrane for immunosensor
Bio-reactor chamber
High temperature, short time heating system and method of
sterilizing or pasteurizing heat sensitive biological fluids
Synergistic combination of t-PA and prostacyclin
Methods of preparing tissue samples
Circulating antigens of dirofilaria immitis, monoclonal antibodies
specific therefor and methods of preparing such antibodies and
detecting such antigens
Interference - resistant liposome specific binding assay
Method for purification of HBc antigen and method for
measurement of HBc antibody by using said purified HBc antigen
Integral multilayer analytical element for measurement of alkaline
phosphatase activity
Method for the quantitative determination of physiological
components in biological fluids
Apparatus for applying stress to cell cultures
Lactobacillus strains and methods of selection
Preparation of 3-oxo-.DELTA..sup.1,4 -steroids
Method of expressing alpha-1-antitrypsin in yeast
Murine host-vector system capable of amplifying and expressing
transfected genes
Method for production of cytidine and/or deoxycytidine
Method of biosynthesis and cells therefor
Process for the transesterification of triglycerides in an aqueous
microemulsion reaction medium in the presence of lipase enzyme
Retrovirus capable of causing AIDS, antigens obtained from this
retrovirus and corresponding antibodies and their application for
diagnostic purposes
Monoclonal antibodies to a broad range of mammalian terminal
deoxynucleotidyl transferases
Process for producing cytotoxic T-cells and compositions
produced by said process
Disposable biological indicator test pack for monitoring steam and
ethylene oxide sterilization cycles
Cell culture flask utilizing a membrane barrier
DNA encoding streptavidin, streptavidin produced therefrom, fused
polypeptides which include amino acid sequences present in
streptavidin and uses thereof
Blood plasma test method
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4341
4342
4343
4344
4345
4346
4347
4348
4,839,297
4,839,298
4,840,034
4,840,035
4,840,771
4,840,772
4,840,784
4,840,785
4349
4350
4351
4352
4353
4354
4355
4,840,793
4,840,794
4,840,802
4,840,807
4,840,891
4,840,892
4,840,893
4356
4357
4358
4,840,894
4,840,895
4,840,896
4359
4360
4,840,897
4,840,898
4361
4,840,899
4362
4363
4,840,900
4,840,901
4364
4,840,902
4365
4,840,903
4366
4367
4368
4,840,904
4,840,905
4,840,906
4369
4370
4371
4,840,907
4,840,908
4,840,934
4372
4373
4374
4375
4,841,023
4,841,024
4,841,055
4,842,693
4376
4377
4378
4,842,767
4,842,857
4,842,869
4379
4380
4,842,871
4,842,935
4381
4382
4,842,995
4,842,996
Test carrier and method for the analytical determination of a
component of a body fluid
Virus inactivating diluents used in immunoassays
Method of freezing vital body fluids
Method of freezing tissue
Incubator for reagents
Antiglaucoma compositions and methods
Use of pyrylium and thiapyrylium compounds as biological stains
Mammal intestinal hormone precursor and its use
Method of reducing tissue damage at an inflammatory site using a
monoclonal antibody
Mastitis vaccine containing antigens from S. aureus
Process for brewing beer while enhancing yeast growth
Branched dextrin production and compositions containing same
Encapsulation of sperm for artificial insemination
Polynucleotide hybridization probes
Electrochemical assay for nucleic acids and nucleic acid probes
Method for detecting a marker for essential hypertension and
diagnostic use thereof
Monoclonal antibodies reactive with immune complexes
Heteropolymeric protein
Modified human insulin and its use as starting material for the
preparation of human insulin
High temperature method for the production of ribavirin
Method for the production of ribavirin using high robose donor
concentrations
Continuous process for the preparation of immobilized
glucoamylase
Restriction endonuclease Dra II
Continuous process for ethanol production by bacterial
fermentation using pH control
Process for producing ethanol from plant biomass using the
fungus paecilomyces sp.
Recovery and reuse of cellulase catalyst in an exzymatic cellulose
hydrolysis process
Process for culturing biological material
Plant generation method
Process for producing optically active dichloropropanol using
microorganism
Culture bottle assembly
Therapeutic method using T cell growth factor
Inactivation of viruses in labile protein-containing compositions
using fatty acids
Purification of antibodies
Desmosine derivatives and reagent for preparing artificial antigens
Apparatus for removing water from ethanol
Heavy duty built aqueous liquid detergent composition containing
stabilized enzymes
Glyphomicins A and B
Method for making fermented beverages
Method and inoculant for preserving agricultural products for
animal feed
Filler for separating optical isomer
Diagnostic method for the evaluation of clinical parameters by
direct collection of biological materials and device for its
accomplishment
Probes comprising modified adenine groups, their preparation and
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4383
4384
4385
4386
4387
4388
4,842,997
4,842,998
4,842,999
4,843,000
4,843,001
4,843,002
4389
4,843,003
4390
4391
4392
4393
4,843,004
4,843,005
4,843,006
4,843,007
4394
4395
4396
4,843,008
4,843,009
4,843,010
4397
4398
4,843,011
4,843,012
4399
4,843,019
4400
4,843,105
4401
4402
4403
4404
4405
4406
4,843,146
4,844,869
4,844,893
4,844,897
4,844,966
4,845,025
4407
4408
4409
4410
4,845,026
4,845,027
4,845,028
4,845,029
4411
4412
4413
4,845,030
4,845,031
4,845,032
4414
4415
4,845,033
4,845,034
4416
4417
4418
4419
4420
4421
4422
4423
4424
4425
4,845,035
4,845,036
4,845,037
4,845,038
4,845,042
4,845,194
4,845,195
4,845,196
4,845,197
4,845,198
their uses
Enhanced luminescent and luminometric assay
Heterohybridoma screening method
Canine heartworm vaccine and diagnostic test
Simultaneous calibration heterogeneous immunoassay
Conjugate for enzyme immuno determinations
Method of selecting recombinant DNA-containing streptomyces
Process for producing shortened target DNA fragments usable in
sequencing large DNA segments
Method for the production of human T-T cell hybrids and
production suppressor factor by human T-T cell hybrids
Process for regenerating corn
RecA promoter dependent polypeptide production
Alcaligenes eutrophus for biodegrading PCBs
Novel microorganisms and a novel process for producing
antibiotics
Pseudomonas putide capable of degrading PCBs
Polymerization-induced separation immunoassays
Monoclonal antibodies for binding HTLV-III proteins, and cell lines
for their production
Novel composition for nucleic acid purification
Immunoassay for detecting acino-foetal differention protein
associated with cancer of the pancreas
Process for the preparation of filler-containing, antionically
modified polyurethane (urea) compositions, the polyurethane
(urea) compositions so-obtained, and the use thereof
Immunologically active polypeptides useful for the preparation of
antimalarial vaccines and of diagnostic kits for the detection of
antisporozoite antibodies
Immunoassay apparatus
EX vivo effector cell activation for target cell killing
Anti-tumor protease preparations
Assaying total IgE levels with fluorogenic enzyme labeled antibody
Biological sample mixing apparatus and method
Assay systems for detecting cell-free T cell antigen receptor
related molecules and the clinical utilities of the assays
Fluorometric assay of allergic reactions
Composition for lipase assay
Method for the determination of sarcosine creatine or creatinine
Use of aniline derivates as coupling components in oxidative color
formation reactions
Recombinant DNA process for producing useful polypeptides
Process for the isolation and purification of alpha-interferons
Process for a continuous fermentative production of low aliphatic
alcohols or organic solvents
Biochemically reacting substrates in subterranean cavities
Enzyme immobilization with a hydrolyzed polysaccharide graft
copolymer
Process for isolation of the B oligomer of pertussis toxin
Process for producing antibiotic LL-D42067.alpha.
Cell culture vial
Adjuvant for immunization
Glycopeptide recovery process
Inhibitor of ribonucleotide reductase
Modified interferon gammas
Monoclonal antibodies and methods for fungal pathogen detection
Hybridoma antibody which binds IL-2 receptor
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4426
4427
4428
4429
4,846,975
4,847,081
4,847,096
4,847,128
4430
4,847,193
4431
4,847,194
4432
4433
4,847,195
4,847,196
4434
4,847,197
4435
4,847,198
4436
4437
4438
4439
4440
4441
4,847,199
4,847,200
4,847,201
4,847,202
4,847,203
4,847,245
4442
4443
4444
4445
4446
4447
4,847,284
4,848,139
4,849,008
4,849,077
4,849,089
4,849,108
4448
4449
4450
4,849,217
4,849,329
4,849,330
4451
4,849,331
4452
4,849,332
4453
4,849,334
4454
4455
4,849,335
4,849,336
4456
4457
4,849,337
4,849,338
4458
4,849,339
4459
4460
4461
4462
4463
4464
4465
4466
4,849,340
4,849,341
4,849,342
4,849,343
4,849,345
4,849,346
4,849,347
4,849,348
Anaerobic digestion process
Synthetic bovine parainfluenza viral proteins
Process for treating whey proteins, and product obtained
Miniaturized yeast identification system
Signal amplification in an assay employing a piezoelectric
oscillator
Colorimetric detection of delta-5-3-ketosteroid isomerase and
immunoassay based thereon
Glucose-6-phosphate dehydrogenase conjugates useful in
polyiodothyronine assays
Stabilized composition of tetrazolium salts
Method for determining the disinfecting effect of a disinfectant and
a test strip suitable therefor
Detection and indentification of bacteria by means of ultra-violet
excited resonance Raman spectra
Agglutination immunoassay and kit for determination of a
multivalent immune species using a buffered salt wash solution
Biosynthesis of unnatural cephalosporins
DNA encoding for CSF-1 and accompanying recombinant systems
Heterocyclic inhibitors of serine proteases
Fermentation vessels
N-demethylefrotomycin
Antifungal fermentation product and derivatives and compositions
thereof
Determining amount of biological material
Root crop growth promotants
Process for solid phase-sequencing of nucleic acid fragments
Disposable electromanipulation chamber
Process for purifying waste water
Novel isolates of bacilus thuringiensis having activity against the
alfalfa weevil, hypera brunneipennis
Process for preparing lymphokine activated killer cells
Photoresponsive redox detection and discrimination
Human papillomavirus 44 nucleic acid hybridization probes and
methods for employing the same
Human papillomavirus 35 nucleic acid hybridization probes and
methods for employing the same
Human papillomavirus 43 nucleic acid hybridization probes and
methods for employing the same
Method for detecting the mutagenicity of substances susceptible of
inducing the deterioration of cellular DNA, utilizing the production
of an SOS response
Oligonucleotide derivatives and production thereof
Assaying allergen specific IgE levels with fluorogenic enzyme
labeled antibody
Simultaneous calibration heterogeneous immunoassay
Method for determination and diagnosis of non-goodposture
glomerulonephritis
Reaction system element and method for performing prothrombin
time assay
Diagnostic test for Staphylococcal mastitis in cattle
Method for carrying out enzyme assays
Process for analysis using a lipid membrane
L-phenylalanine dehydrogenase and use thereof
Method for determining thioredoxin reductase activity
Colorimetric biological assay
Post-transcriptional heme regulated heterologous gene expression
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4467
4468
4469
4470
4,849,349
4,849,350
4,849,351
4,849,352
4471
4472
4473
4,849,353
4,849,354
4,849,355
4474
4,849,356
4475
4,849,357
4476
4477
4478
4479
4,849,358
4,849,359
4,849,360
4,849,403
4480
4481
4482
4483
4484
4,849,411
4,849,500
4,849,505
4,849,506
4,849,507
4485
4486
4487
4488
4489
4490
4,849,509
4,849,510
4,851,115
4,851,210
4,851,235
4,851,329
4491
4,851,330
4492
4493
4,851,331
4,851,332
4494
4,851,333
4495
4,851,334
4496
4,851,335
4497
4498
4499
4500
4501
4502
4503
4504
4,851,336
4,851,337
4,851,338
4,851,339
4,851,340
4,851,341
4,851,342
4,851,343
4505
4506
4507
4508
4509
4,851,344
4,851,345
4,851,346
4,851,347
4,851,348
in yeast using the leg hemoglobin leader sequence
Genes for biologically active proteins
Novel DNA, production and use thereof
Multiple reading frame Escherichia coli expression vectors
Antibody purification process
Immunocapture of enzyme inhibitor, enzyme complexes and uses
thereof
Process for producing menaquinone-4
Method of transferring genes into cells
Fructosyl transferase and the preparation of fructose oligomers
therewith
Method for the preparation of a hydrophobic enzyme-containing
composition and the composition produced thereby
Method for culturing bordetella pertussis, a pertussis toxoid and a
pertussis vaccine
Fish growth hormone polypeptide
Apparatus and method for confining and decontaminating soil
Protein C activator, methods of preparation and use thereof
Modulation of animal cellular responses with compositions
containing 8-substituted guanine derivatives
Polyamide from diacetylene dicarboxylic acid compound
Detectable molecules, method of preparation and use
Leukoregulin, an antitumor lymphokine, and its therapeutic uses
Human suppressor factor
Monoclonal antibodies against melanoma-associated antigens and
hybrid cell lines producing these antibodies
Process for preparing glycosidic linkage related antigen
Separator with movable receptacles
Blood typing device
Production of fermented whey products containing an emulsifier
Immunoassay employing optical pulse particle size analysis
Method for detection, identification and quantitation of non-viral
organisms
Method and kit for polynucleotide assay including primerdependant DNA polymerase
Choriocarcinoma monoclonal antibodies and antibody panels
Method and composition for the detection and diagnosis of
Legionella pneumophila
Monoclonal antibodies specific to in vivo fragments derived from
human fibrinogen, human fibrin I or human fibrin II
Process and reagent for the specific determination of HDL
cholesterol in serum or plasma
Composition, kit, and method for assaying heparinano a method
for making the composition
Extraction of test substances
Method for diagnosing the presence of bacteria
Extraction of anti-mutagenic pigments from algae and vegetables
Strains of Bacillus toxic to Coleoptera
Immunoaffinity purification system
Method for producing acrylamide using a microorganism
Microbiological production of essential fatty acids
Microbial reduction of monocarboxylic and dicarboxylic acids in the
presence of carbon monoxide and/or formates plus mediators
Fibrinophilic urokinase complex and method for production thereof
Chemically defined growth medium
Bulk starter medium
Biologically pure escherichia coli cell line which is a deoR.sup.-
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4510
4511
4512
4513
4514
4515
4,851,349
4,851,350
4,851,351
4,851,353
4,851,354
4,851,356
4516
4517
4518
4519
4520
4,851,393
4,851,510
4,851,511
4,851,512
4,851,560
4521
4522
4,851,572
4,853,210
4523
4524
4525
4526
4,853,231
4,853,262
4,853,324
4,853,325
4527
4528
4,853,326
4,853,327
4529
4530
4531
4,853,328
4,853,329
4,853,330
4532
4,853,331
4533
4534
4,853,332
4,853,333
4535
4536
4,853,334
4,853,335
4537
4,853,464
4538
4539
4,855,045
4,855,051
4540
4,855,108
4541
4542
4543
4,855,149
4,855,224
4,855,225
4544
4545
4,855,226
4,855,227
4546
4547
4548
4,855,228
4,855,229
4,855,230
mutant and which is more transformation efficient with foreign
plasmids than deoR.sup.+ escherichia coli cell lines, processes for
obtaining these cell lines, methods of use
Expression vectors encoding cardionatrin and cardiodilatin
Microbial desulfurization of coal
Culture vessel
Method and test composition for determination of lipid peroxide
Apparatus for mechanically stimulating cells
Immunoassay for human chorionic gonadotropin
Method for utilizing an exocellular polysaccharide isolated from
zoogloea ramigera
Monoclonal antibodies to novel melanoma-associated antigens
Monoclonal antibody that specifically binds to disialosyl Le.sup.a
Novel human interleukin-2 polypeptide derivative
Inositol triphosphates
.gamma.-L-glutamyl-4-nitroanilide derivatives and process for
determining .gamma.-GTP activity using the same
Method of staining cells with a diazo dye and compositions thereof
Method for preparation of tastable matters consisting primarily of
low molecular weight peptides
Cover film for microscopy
Liver assist device employing transformed cell lines
Saliva test for feline leukemia virus
Carbohydrate perturbations of viruses or viral antigens and
utilization for diagnostic prophylactic and/or therapeutic
applications
Enhanced phthalazinedione chemiluminescence
Reagent for assaying hydrogen peroxide and method of
quantitative assay for hydrogen peroxide
Stabilization of microbial rennet
Human tissue plasminogen activator
Cloning and expression of Bacillus thuringiensis toxin gene toxic to
beetles of the order Coleoptera
Structural genes, plasmids and transformed cells for producing
cysteine depleted muteins of biologically active proteins
Production of rotavirus in yeast
Method for the degradation of volatile chlorinated aliphatic
hydrocarbons using pseudomonas fluorescens
Colloidal gold particle concentration immunoassay
Hybridoma cell line XMMBR-B14 and monoclonal antibody which
is specific for a non-cross reactive epitope of CEA
Method and apparatus for the separation of organic substances
from a suspension or solution
Microbial treatment of wastewater to remove tertiary butyl alcohol
Member of analytical element for the analysis of liquid sample
containing solid
Method for producing novel dried compositions containing
polysaccharides
Molecularly cloned diagnostic product and method of use
Method of detecting electrophoretically separated oligonucleotides
Novel competitive assay for theophylline and reagent for use
therein
Rapid detection of mycoplasmas
Multiple oxidative indicator system for visual determination of
hydrogen peroxide
Measurement method of peroxidase activity
Microorganism inhibition of frost damage to plants
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4549
4550
4551
4,855,231
4,855,232
4,855,233
4552
4553
4554
4,855,234
4,855,235
4,855,236
4555
4,855,237
4556
4557
4558
4559
4560
4561
4562
4,855,238
4,855,242
4,855,409
4,855,494
4,856,073
4,857,152
4,857,273
4563
4,857,300
4564
4565
4,857,318
4,857,319
4566
4,857,339
4567
4568
4569
4,857,451
4,857,452
4,857,453
4570
4,857,454
4571
4,857,455
4572
4573
4,857,456
4,857,457
4574
4575
4576
4577
4578
4579
4580
4,857,458
4,857,459
4,857,460
4,857,461
4,857,462
4,857,463
4,857,464
4581
4582
4,857,465
4,857,466
4583
4584
4585
4,857,467
4,857,468
4,857,469
4586
4587
4588
4,857,470
4,857,474
4,857,634
4589
4,857,639
Regulatory region for heterologous gene expression in yeast
Method for production of glucose by use of transglucosidase
Process for carrying out enzymatic reactions in an organic solvent
Biologically active protein immobilized with a polymeric fibrous
support
Monoclonal antibodies to human leukocyte antigens
Process for plant tissue culture propagation
Double-stranded DNA having sequences complementary to a
single-stranded DNA and derived from a bean golden mosaic virus
Recombinant gamma interferons having enhanced stability and
methods therefor
Method of detecting antibodies
Novel polypeptides and method of producing same
Process for producing citric acid
Automated microbiological testing apparatus and method
Peroxide electrodes
Biosensors
Cytological and histological fixative formulation and methods for
using same
Bordetella bronchiseptica pilus subunit protein vaccine effective
against bordetella pertussis
Method for preserving liposomes
Method for making cereal products naturally sweetened with
fructose
Method of compensating and calibrating a flow cytometer, and
microbead standards kit therefor
Assay for carcinoma of breast, colon and ovary
Immunoassay device
Spectrophotometric method for kinetic absorbance measurements
in two-phase enzyme immunoassay and apparatus therefor
Method for the determination of peroxidase using fluorogenic
substrates
Assay of Bone morphogenetic protein (BMP) and anti-BMP
antibody for the diagnosis of bone disorders
Screening test for large intestinal cancer
Installation and plant for the recovery of energy from waste and
residues
Stain for acid-fast bacilli
Cycloheximide resistant gene
Continuous process for the enzymatic preparation of isomaltulose
Process for obtaining D(+)-naproxen
Method of preparing intracellular parasites for storage
Mist cultivation of cells
Whole plant regeneration via organogenesis and somaclonal
variation in glycine species
Probe for detection of specific human leukemias
Carbon and energy source markers for transformation of strains of
the genes Pichia
Process for preparing optically active 2-halo-1-phenyl ethanol
Process for preparing optically active mercapto compound
Method for the preparation of bacterial clones carrying optimal
genetic information for the production of the factor for release of
human growth hormone in Escherichia coli
Phycoerythrins useful in fluorescent conjugates
Peptides useful in vaccination against enteroviruses
A-associated H-antigens, monoclonal antibodies specific thereto
and methods for employing the same in blood typing
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4590
4591
4592
4593
4594
4,859,377
4,859,419
4,859,421
4,859,464
4,859,474
4595
4,859,506
4596
4597
4598
4,859,538
4,859,581
4,859,582
4599
4,859,583
4600
4,859,584
4601
4602
4603
4604
4605
4,859,585
4,859,586
4,859,587
4,859,588
4,859,589
4606
4607
4,859,590
4,859,591
4608
4,859,592
4609
4610
4,859,593
4,859,594
4611
4612
4613
4614
4,859,595
4,859,596
4,859,597
4,859,598
4615
4,859,599
4616
4617
4,859,600
4,859,601
4618
4619
4620
4,859,602
4,859,603
4,859,604
4621
4622
4623
4,859,609
4,859,610
4,859,613
4624
4,859,655
4625
4,859,736
4626
4627
4628
4,861,381
4,861,482
4,861,509
4629
4,861,519
Starch encapsulation of entomopathogens
Diagnostic manifold apparatus
Disposable antigen concentrator and detector
Method for the purification of parasite antigenic factors
Method of making an enzyme sweetened cereal product
Dispersion for protective coatings and method for applying such
coatings
Novel lipid-protein compositions and articles and methods for their
preparation
Endoglycosidase assay
Fluorescent conjugates for analysis of molecules and cells
Chemiluminescent immunochemical technique for low molecular
weight antigens
Cell growth rate determination by measurement of changes in
cyanine dye levels in plasma membranes
In-vitro methods for identifying compositions which are agonists
and antagonists of estrogens
Device for cultivating bacteria
Recombinant herpes simplex viruses, vaccines and methods
Production of a single cell protein
Enzymatic method for preparation of epoxy compounds
Enzymatic synthesis of cyclodextrins using .alpha.-glucosyl
fluoride as substrate for cyclodextrin
.alpha.(1.fwdarw.4)glucosyltransferase
Transamination process for producing amino acids
Production of picolinic acid and pyridine products via
pseudomonas
New physiologically active substance, arphamenine and
production thereof
Microorganisms for biodegrading toxic chemicals
Method for preparing rabbit monoclonal antibodies, the cell lines
used therein and the antibodies produced thereby
Cloning system for Kluyveromyces species
Production of phage and phage-associated lysin
Antibiotic LL-D42067.beta.
Antibiotic A26201-1 and antibiotic A26201-2 produced by a novel
strain of actinoplanes
Recombinant procaryotic cell containing correctly processed
human growth hormone
Streptomyces Bgl protein gene promoter
Process for the preparation of stereoisomers of 1aminoalkylphosphonic and phosphinic acids
Personal diagnostic kit
Composition for stabilization of diagnostic reagents
Novel receptors for efficient determination of ligands and their
antagonists or agonists
Immunoassay incubation device
Immunoassays for glutathione and antibodies useful therein
Urdamycin G and derivatives thereof, a process for their
preparation and their use
Synthetic polystyrene resin and its use in solid phase peptide
synthesis
Process for the enzymatic preparation from sucrose of a mixture of
sugars having a high content of isomaltose, and products obtained
Selenium detoxification
Enzymatic detergent and bleaching composition
Method for volume reduction of low activity organic wastes from
nuclear power plants by anaerobic decomposition
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4630
4631
4,861,552
4,861,581
4632
4,861,589
4633
4634
4635
4636
4,861,704
4,861,705
4,861,706
4,861,707
4637
4,861,708
4638
4639
4640
4641
4642
4643
4644
4645
4,861,709
4,861,710
4,861,711
4,861,712
4,861,713
4,861,714
4,861,715
4,861,716
4646
4,861,717
4647
4648
4649
4650
4,861,718
4,861,719
4,861,720
4,861,721
4651
4,861,722
4652
4,861,723
4653
4654
4655
4,861,724
4,861,725
4,861,796
4656
4657
4,861,869
4,863,565
4658
4659
4660
4,863,688
4,863,689
4,863,727
4661
4,863,728
4662
4663
4,863,729
4,863,732
4664
4665
4666
4667
4668
4669
4,863,847
4,863,848
4,863,849
4,863,850
4,863,851
4,863,852
Biological reaction layer and its preparation
Detection of necrotic malignant tissue and associated therapy
Method for therapeutically treating abnormal cells expressing a
major histocompatibility complex class II antigen using cytolytic
inducer T4 cells
Processes for development of acceptance of transplanted organs
and tissues
Method for removing components of biological fluids
Assay for hepatitis a virus
Human immunodeficiency virus antigen
Restriction fragment analysis of individuals using cardiovascular
system probes
Detection and/or identification of microorganisms in a test sample
using bioluminescence or other exogenous genetically-introduced
marker
Recombinant DNA clone encoding laminin receptor
Sheet-like diagnostic device
Analysis element for determination of a coagulation parameter
Novel method for determining cholinesterase activity
Weighted collagen microsponge for immobilizing bioactive material
Process for the production of nourseothricine and its adsorbate
Rearrangement process
Microorganisms and plasmids for the constitutive formation of
creatinamidinohydrolase and processes for the production thereof
Gene coding for thermostable beta-galactosidase, bacillus subtilis
having the gene, enzyme coded by the gene and a process for the
production thereof
DNA constructs for retrovirus packaging cell lines
Oncornavirus vaccines and feline alpha-type interferon
Bacteria for cellulose digestion
Coryneform bacteria carrying recombinant plasmids and their use
in the fermentative production of L-lysine
Microbiological desulfurization of coal and coal water admixture to
provide a desulfurized fuel
Process for preparing optically active 2,2'-dihydroxy-1,1'binaphthyl
Mammalian cell culture apparatus
Gentisic acid derivatives having antibiotic activity
Coupling agents for joining radionuclide metal ions with
biologically useful proteins
Sheeted products formed from reticulated microbial cellulose
Method of decontaminating surfaces on or near living cells with
vapor hydrogen peroxide
Apparatus for the detection of chemiluminescence
Combination therapy using interleukin-2 and tumor necrosis factor
Monoclonal anti-alpha-amylase antibody which non-specifically
inhibits the enzyme activity of human alpha-amylase
Method for preparing a macromolecular monoclonal antibody
composition
Injectable composition for inductive bone repair
Process for directly determining apurinic and apyrimidinic sites in
DNA
Double-stranded vector and process using it
Automatable process for sequencing nucleotide
Method for diagnosis of rheumatoid arthritis
Monoclonal antibody to prostate secretory protein
Method of detecting, isolating and purifying clostridium difficile
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4670
4671
4,863,853
4,863,854
4672
4,863,855
4673
4,863,856
4674
4675
4676
4677
4,863,857
4,863,858
4,863,859
4,863,860
4678
4,863,861
4679
4680
4681
4682
4,863,862
4,863,863
4,863,864
4,863,865
4683
4684
4685
4,863,866
4,863,867
4,863,868
4686
4,863,869
4687
4688
4,863,872
4,864,019
4689
4,864,020
4690
4,865,771
4691
4692
4693
4694
4695
4696
4,865,841
4,865,871
4,865,966
4,865,967
4,865,968
4,865,969
4697
4,865,970
4698
4699
4700
4701
4702
4,865,971
4,865,972
4,865,973
4,865,974
4,865,975
4703
4704
4705
4706
4,865,976
4,865,977
4,865,978
4,865,979
4707
4,865,980
4708
4,865,981
toxin A and its receptors
Method of determining the diagnostic value of monitoring serumCEA-levels in a carcinoma patient undergoing therapy
Monoclonal antibodies to mucin-like human differentiation antigens
Novel cloning vehicles for polypeptide expression in microbial
hosts
Weighted collagen microsponge for immobilizing bioactive
materials
Polypeptide complementary to peptides or proteins having an
amino acid sequence or nucleotide coding sequence at least
partially known
Restriction endonucleas DRA III
Process for preparing optically active glycerol derivatives
Fat processing
Biochemical process to produce catechol or 1,2dihydroxycyclohexa-3,5-diene compound(s)
Microbial method of producing C.sub.3 and/or C.sub.4
hydrocarbons
Method of producing somatic hybrids of the genus Lycopersicon
Glucoamylase gene of rhizopus oryzae
Preservation by cold storage
Bradyrhizobium japonicum mutants exhibiting superior soybean
nodulation
Gas permeable bio-test pack
Apparatus for detecting the presence of micro organism in liquid
Anti-human IGM immunoadsorbent and process for producing said
immunoadsorbent
Novel pseudomonas microorganism for biodegradation of liquid
scintillation cocktails
Antibodies to inhibin and conjugates produced therefrom
Monoclonal antibodies and cell lines for parathyroid tissue-specific
antigen parathyroid-specific
Process for preparing L(-)-carnitine chloride from 3,4-epoxybutyric
esters and novel intermediate compounds
Methods and compositions for transient elimination of humoral
immune antibodies
Method for cryopreparing biological tissue
Method for detecting antibodies to human immunodeficiency virus
Autoradiographic gene-screening method
DNA sequencing
Production of microorganisms
Method of detecting ribosomal protein antibodies in systemic lupus
erythematosus
Monoclonal antibody specific to a common determinant site of
neutrophils and eosinophils
Antibody-based bioassay for enzyme-inducing chemicals
Process for extractive fermentation
Bacterial methionine N-terminal peptidase
Process for recuperation of the proteins lost by the dairy industry
Method of cyclodextrin manufacture using an immobilized
cyclodextrin glycosyltransferase
Increasing monascus pigment production
Lipolytic splitting of fats and oils
Novel bacteriophage and method for breeding thereof
Monoclonal antibodies for DNA-RNA hybrid complexes and their
uses
Cloning and expression of Bacillus Thuringiensis toxin gene toxic
to bettles of the order coleoptera
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4709
4,865,982
4710
4711
4712
4713
4714
4715
4716
4,865,983
4,865,984
4,865,985
4,865,986
4,865,987
4,865,988
4,865,989
4717
4,865,990
4718
4719
4720
4721
4722
4723
4724
4,865,995
4,865,998
4,866,033
4,866,034
4,866,081
4,866,166
4,866,167
4725
4,867,797
4726
4727
4728
4729
4730
4,867,975
4,868,001
4,868,103
4,868,104
4,868,105
4731
4,868,106
4732
4733
4734
4735
4736
4737
4,868,107
4,868,108
4,868,109
4,868,110
4,868,111
4,868,112
4738
4739
4740
4,868,113
4,868,114
4,868,115
4741
4742
4,868,116
4,868,117
4743
4744
4,868,118
4,868,119
4745
4746
4747
4,868,120
4,868,121
4,868,122
4748
4749
4750
4751
4752
4,868,123
4,868,124
4,868,125
4,868,130
4,868,131
Cloned streptomycete gene
Cleaning compositions containing protease produced by vibrio and
method of use
Dynamic continuous flow enzyme reactor
Containers for culturing and testing of vertebrate lenses
Temperature control apparatus
Thermal gradient-incubator
Microbiological culture device
Eukaryotic vectors and plasmids having PGK regulatory signals
Protein adsorbent including a colored compound containing a
quaternary ammonium especially amidinium or guanidimium
cationic group and a cellulose reactive group
Method for measuring a concentration of saccharides having a low
molecular weight and sensor for measuring the same
Monoclonal antibodies to human lung cancers and method
Oligopeptides from bovine blood
Refined detoxified endotoxin
Microbicidal preservative composition
Bioassay for transforming genes and genes detected thereby
Detection of human oral cells by nucleic acid hybridization
Method for cleaning instruments used for analyzing proteincontaining biological liquids
Live attenuated temperature-sensitive avian infectious bronchitis
virus vaccines and preparation and use thereof
Feed for animals and process for producing same
Analyte detection by means of energy transfer
Homogeneous assay for specific polynucleotides
Solution phase nucleic acid sandwich assay
Analytical element and method for determining a component in a
test sample
Method for detecting antibodies against neuropeptides and drugs
in human body fluid
Multiple-antibody detection of antigen
Immunological antibody complex, its preparation and its use
Methods and device for detection of microorganisms
Gram-positive expression control sequences
Novel procoagulant proteins
Recombinant DNA vector encoding human endothelial cell growth
factor
Method for elevating glutathione levels
Enzyme composition
Introduction and expression of foreign genetic material in epithelial
cells
BBM-1675, a new antitumor antibiotic complex
Cloning and expression of the 47-kilodalton antigen of treponema
pallidum
Hematopoietic growth factors
Method of recovering both silver and a base for sensitive materials
from sensitive materials by utilizing micro-organisms
Islet isolation process
Arrangement for growing permanent forms of microorganisms
Apparatus for the intensive, controlled production of
microorganisms by photosynthesis
Vapor sterilizable bioreactor
Promoter
Methods for conducting specific binding assays
Competitive binding immunoassay process
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4753
4754
4755
4756
4757
4758
4,868,159
4,868,285
4,868,293
4,868,767
4,869,017
4,869,819
4759
4,869,826
4760
4761
4,869,875
4,869,877
4762
4763
4,869,901
4,870,002
4764
4765
4766
4767
4,870,003
4,870,004
4,870,005
4,870,006
4768
4769
4,870,007
4,870,008
4770
4771
4772
4,870,009
4,870,011
4,870,012
4773
4,870,013
4774
4775
4,870,014
4,870,015
4776
4777
4778
4779
4780
4,870,016
4,870,017
4,870,018
4,870,019
4,870,020
4781
4782
4,870,021
4,870,022
4783
4,870,023
4784
4785
4,870,026
4,870,053
4786
4787
4788
4789
4,870,159
4,870,165
4,870,172
4,870,185
4790
4791
4792
4793
4,871,386
4,871,440
4,871,539
4,871,571
Novel substances KS-501 and KS-502 and process for their
preparation
Antibiotic production
Polysaccharide polymer made by xanthomonas
Reflectance gradient densitometer
Macroalgae culture methods
Apparatus for biomethanation
Cellular adsorbents for removal of viral contaminants from blood
and complex protein solutions
Method of detecting or determining histamine in histamine
containing materials, particularly body fluids and an analytical
agent for use in such method
Composting facility
Method and compositions for helmintic, arthropod ectoparasitic
and acaridal infections with novel agents
Method of prevention of oxidative injury to cells
Simultaneous enzyme immunoassay for detecting antigen and/or
antibody in humans
Apparatus and method of analyzing nucleic acid molecules
Multilayer analysis element
Antigenic material for a chagas' disease detection system
Immobilized biotinylated receptor in test device, kit and method for
determining a ligand
Secretory expression in eukaryotes
Method of obtaining gene product through the generation of
transgenic animals
Method for obtaining lipids from fungus bodies
Bacterial method and compositions for linalool degradation
SV40 early and RSV promoters useful in saccharomyces
expression
Cloning of thermolabile glucoamylase gene into saccharomyces
cerevisiae
Method and composition for producing lectin in microorganisms
Process of chemical modfication of protides and the products thus
modified
Bacterial methionine N-terminal peptidase
Process and apparatus for gassing liquids
Antibiotic LL-C19004
Preparation of compositions including acid-resistant bifidobacteria
Pure culture of antibiotic A42125-producing strains of Nocardia
aerocolonigenes
Apparatus and method for producing miso
Recombinant baculovirus occlusion bodies in vaccines and
biological insecticides
Non-A, non-B. hepatitis, virus, methods of identification
purification, characterization, diagnosis and immunization
Novel compositions and processes
LEU3 gene sequence of S. cerevisiae and use in regulation of
amino acid synthesis
Antifungal antibiotics
Bisucaberin
Hapalindoles
Biological control of wild poinsettia and other weedy spurges with
a fungal pathogen
Biosensor
Biodeodorizer and process for preparing same
Dietetic foodstuff containing low calorie bulking agent
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4794
4,871,659
4795
4,871,660
4796
4797
4798
4,871,661
4,871,662
4,871,663
4799
4800
4,871,664
4,871,665
4801
4802
4,871,666
4,871,667
4803
4,871,668
4804
4,871,669
4805
4806
4,871,670
4,871,671
4807
4808
4809
4810
4,871,673
4,871,674
4,871,675
4,871,676
4811
4812
4,871,677
4,871,683
4813
4,871,711
4814
4815
4816
4817
4818
4819
4,871,716
4,871,824
4,871,834
4,871,835
4,871,838
4,871,866
4820
4821
4822
4823
4,872,986
4,873,016
4,873,186
4,873,187
4824
4825
4826
4827
4828
4829
4,873,188
4,873,189
4,873,190
4,873,191
4,873,192
4,873,194
4830
4,873,195
4831
4832
4,873,196
4,873,230
Reagent for detecting non-A, non-B viral hepatitis (NANBH) and
an immunoenzymatic method for detecting NANBH antigens in
fecal extracts
Luminescence immuno-test kits, method for stabilizing same and
quality control thereof
Process for testing the carcinogenicity of a material or the
presence of cancer-inducing factors in an environment
Device for shipping microbiology test samples
Exporession vector for human TnF
Type II restriction endonuclease Dsa I with process for obtaining it
and the use thereof
Process for the preparation of exocellular biopolymers
Process for preparing a lipid composition having upon
saponification a high gama-linolenic acid content
Process for preparing muconic acid
Microorganism ATCC53716 and process for producing
acetophenone
Production of natural flavor aldehydes from natural source primary
alcohols C.sub.2 -C.sub.7
Molecular cloning and characterization of a gene sequence coding
for human relaxin
Immobilization of biological cells in polytetrafluoroethylene matrix
Process for the decontamination of soil by means of
microorganisms
Culture cell
Storage container of samples for analysis
Cell culture incubator
Method of collecting and analyzing a sample of blood when
monitoring heparin therapy
Apparatus and method using a new reaction capsule
Active material produced from metal oxide/hydroxide particles and
phosphate esters
Magnetically responsive, hydrophilic microspheres for
incorporation of therapeutic substances and methods of
preparation thereof
Variably crosslinked polymeric supports
Monoclonal antibodies specific to CEA
Analogs of hGH having antagonistic activity, and uses thereof
Probes and methods for detecting activated ras oncogenes
Lysocellin solids purification process
Use of bacteria for control of algal bloom in wastewater, lagoons,
or ponds
Enzymatic detergent composition
Cornea storage medium
Bifunctional DNA-protein conjugating agent
Method, monoclonal antibody, and monoclonal antibody fragments
for detecting human non-small cell lung carcinomas and cell line
for producing such antibodies
Monoclonal antibodies to bluetongue virus antigen
Heterodimeric T lymphocyte receptor
Genetic transformation of zygotes
Process for site specific mutagenesis without phenotypic selection
Process for preparing enzyme preparation
Block-formed basidiomycete and a method of cultivation for the
same
Protoplasts of temperature-sensitive strains of neurospora crassa
OS-1
Composition for the preservation of organs
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4833
4,873,313
4834
4835
4836
4,873,316
4,873,317
4,874,044
4837
4838
4839
4,874,616
4,874,690
4,874,691
4840
4841
4,874,692
4,874,693
4842
4,874,694
4843
4,874,695
4844
4845
4846
4847
4848
4849
4,874,696
4,874,697
4,874,698
4,874,699
4,874,700
4,874,701
4850
4851
4,874,702
4,874,703
4852
4,874,704
4853
4854
4855
4,874,705
4,874,706
4,874,707
4856
4,874,708
4857
4,874,710
4858
4859
4,874,748
4,874,845
4860
4861
4862
4863
4864
4,874,853
4,875,921
4,876,024
4,876,067
4,876,186
4865
4,876,187
4866
4,876,188
4867
4868
4,876,189
4,876,190
4869
4,876,191
Specific hybridoma cell line and monocolonal antibodies produced
from such specific hybridoma cell line and method of using such
monoclonal antibodies to detect carcinoembryonic antigens
Isolation of exogenous recombinant proteins from the milk of
transgenic mammals
Method of separating or purifying proteins and other biopolymers
Method for oil recovery using a modified heteropolysaccharide
Method for producing mucoid and phage resistant group N
streptococcus strains from non-mucoid and phage sensitive parent
strains
Lyophilization of red blood cells
Membrane-supported immunoassays
Binder composition and analytical element having stabilized
peroxidase in layer containing the composition
Method for assessing placental dysfunction
Use of phosphoprotein patterns for diagnosis of neurological and
psychiatric disorders
Rapid indentification of yeast and other fungal microorganisms by
enzyme detection
Novel bacterium inducible to produce unique steroid-transforming
enzymes: preparation and applications thereof
Novel Host e. coli and use thereof
Process for producing tryptophan
Reaction method for transesterifying fats and oils
Process for the production of L-malic acid
Preparation of coniferylaldehyde by a microorganism
Vectors and methods for making such vectors and for expressive
cloned genes
Expression vectors for use in E. coli
Method for inhibiting food-borne human pathogens and preventing
microbial spoilage in refrigerated foods using a Lactobacillus
DNA encoding an antigenic protein derived from Eimeria tenella
and vaccines for prevention of coccidiosis caused by Eimeria
tenella
Manufacture and use of tagetitoxin
Process for producing an aqueous suspension of nitrifying bacteria
Process for the preparation of intra-venously administered
gamma-globulins and the gamma-globulins obtained
Assay and product in which binder and liposomes are supported
on a solid support
Cloning vectors for streptomyces and use thereof in macrolide
antibiotic production
T lymphocyte receptor subunit
Synthetic oligonucleotides useful in diagnosis of chronic
myelogenous leukemia
Bacterial agricultural inoculants
Enzymatic detergent additive, a detergent, and a washing method
Multilayer test strip device with a dissolvable reagent layer
Detection and differentiation of coxiella burnetii in biological fluids
Nucleic acid compositions with scissile linkage useful for detecting
nucleic acid sequences
Novel immunochemical method for assaying stable glycosylated
hemoglobin
Process for the quantification of cell populations or subpopulations
and a reagent suitable therefor
Peridinin-chlorophyll complex as fluorescent label
Immobilization of biologically active substances with carrier bond
antibody
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4870
4871
4,876,192
4,876,193
4872
4873
4,876,194
4,876,195
4874
4875
4876
4,876,196
4,876,197
4,876,198
4877
4878
4879
4880
4881
4882
4883
4884
4885
4886
4,876,199
4,876,200
4,876,201
4,876,202
4,876,207
4,876,288
4,876,335
4,877,036
4,877,582
4,877,615
4887
4888
4,877,616
4,877,659
4889
4890
4,877,725
4,877,726
4891
4,877,727
4892
4,877,728
4893
4894
4895
4,877,729
4,877,730
4,877,731
4896
4897
4,877,732
4,877,733
4898
4899
4,877,734
4,877,735
4900
4,877,736
4901
4,877,737
4902
4903
4904
4,877,738
4,877,739
4,877,740
4905
4,877,741
4906
4907
4908
4909
4,877,746
4,877,747
4,877,776
4,877,864
Detection of antibodies against a chorionic gonadotropin-like
substance
Determination of suppressor functional reserve
Protein L and subfragments thereof, with immunoglobulin binding
activity, a process for preparing thereof, reagent kit,
pharmaceutical composition and a peptococcus magnus strain
Process for producing 2-keto-D-glucaric acid
Method of continuously producing ethanol from sugar-containing
substrates
Eukaryotic regulatable transcription
Method for production of an enzyme granulate
Hybridomas producing monoclonal antibodies to mono-, di-, and
trifucosylated type 2 chain
New strains of pseudomonas putida
Method for biodegrading PCBS
Chimeric plasmids
Compositions for the detection of high levels of hydrogen peroxide
Carrier material for immobilization of microorganisms
Poly-labelled oligonucleotide derivative
Swab transport system
Chemical sensor device with field effect transistor
Antifungal product
Process for preparing xerosin II and xerosin III, improved
biological response modifiers
Multiwell assay/culture strip
Immunoassays for antibodies which bind to the acquired
immunodeficiency virus
Method for the detection of acute-phase toxoplasma infection
Substrate for determining leucine aminopeptidase or gammaglutamyltranspeptase activity
Biotransformation of L-tyrosine and L-phenylalanine to 2,5dihydroxyphenylacetic acid followed by polymerization to melanin
pigments
Recombinant DNA encoding novel family of primate hematopoietic
growth factors
Microbiological method for producing ethylene
Fermentation process for carboxylic acids
Biochemical process for the preparation of new organofluorine
compounds
Glucose dehydrogenase and its production
Microbiologically produced .alpha.-acetylamino cinnamic acid
acylase, method of its production and its use
Process for producing 2-keto-L-gulonic acid
Aerobic microorganism for the degradation of chlorinated aliphatic
hydrocarbons
Attenuated pseudorabies virus which has a deletion in at least a
portion of a repeat sequence and vaccine containing same
Biological control of damping off and root rot and inoculum
preparation therefor
Antiammonia azotobacter and the use thereof
Production of cells
Treatment of human plasma with brown recluse spider toxin to
emulate a lupus anticoagulant
Methods of carrying out assays for lipoproteins and
apolipoproteins
Optical assay: method and apparatus
K-252 compounds
Osteoinductive factors
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4910
4,877,865
4911
4912
4913
4,877,867
4,877,868
4,878,312
4914
4915
4916
4,878,936
4,879,112
4,879,211
4917
4,879,212
4918
4,879,213
4919
4920
4,879,214
4,879,215
4921
4922
4923
4924
4925
4926
4,879,216
4,879,217
4,879,218
4,879,219
4,879,220
4,879,221
4927
4928
4,879,222
4,879,223
4929
4,879,224
4930
4931
4932
4933
4934
4,879,225
4,879,226
4,879,227
4,879,228
4,879,229
4935
4936
4937
4,879,230
4,879,231
4,879,232
4938
4,879,233
4939
4,879,234
4940
4941
4942
4943
4,879,235
4,879,236
4,879,237
4,879,238
4944
4,879,239
4945
4,879,240
4946
4,879,241
4947
4948
4949
4,879,249
4,879,282
4,879,283
Bovine interferon
Antibodies for the detection of mammalian ras gene products,
method of preparing and method of using same
Radionuclide antibody coupling
Method for culturing and cultivating fungi
Method to enhance root nodulation in legumes and inoculum
preparation therefor
Monoclonal antibodies agaisnt GnRH
Rapid immunoagglutination test for presence of HIV in body fluids
Peptide composition and method for the detection of antibodies to
HTLV-III
Synthetic polypeptides and antibodies related to Epstein-Barr virus
early antigen-diffuse
Differentiation of nucleic acid segments on the basis of nucleotide
differences
Concentrating immunochemical test strip
Specific antibody against heart muscle light chains, a process for
the preparation thereof and a reagent containing it
Test for Rhizoctonia brown and yellow patch
Antibody for C.difficile
Immunoassay utilizing monoclonal high affinity IgM antibodies
Crosslinking receptor-specific probes for electron microscopy
Process for determination of .gamma.-GTP activity
Method of isolating tumor-secreted products using a novel proteinfree medium
Method for producing protein containing nonprotein amino acids
DNA sequences, recombinant DNA molecules and processes for
producing human phospholipase inhibitor polypeptides
Enhanced production of antibodies utilizing insolubilized immune
complexes
Novel human physiologically active polypeptide
Production of a recombinant human colony stimulating factor
Microbial production of polyfructose
Method for preparing 2,5-diketo-D-gluconic acid
Escherichia coli Candida maltosa Saccharomyces cerevisiae
shuttle vectors and method for making
Transformation of yeasts of the genus pichia
Multilayered structure containing immobilized blud-green algae
Novel Aspergillus niveus microorganism used for the chiral
reduction of carbonyl groups
Process for the purification and recovery of formatedehydrogenase (FDH) from Candida boidinii, and FDH-containing
product
Process for producing protease by cultivating a proteaseproducing mold in a liquid medium
Method for producing a recombinant baculovirus expression vector
Use of peptides in control of cell attachment and detachment
Deodorant and method for preparing and storing same
Method of culturing freeze-dried microorganisms and resultant
preparation
Microbial control of hydrogen sulfide production by sulfate
reducing bacteria
Tylosin resistance-conferring gene, designated tlrB, for use in
streptomyces and other organisms
Linker compounds, linker-compound-ligands and linkercompound-receptors
Medical application for heparin and related molecules
Solution for the preservation of organs
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4950
4951
4952
4,879,374
4,879,431
4,880,542
4953
4,880,647
4954
4,880,731
4955
4956
4957
4958
4,880,732
4,880,734
4,880,735
4,880,736
4959
4960
4961
4962
4963
4964
4,880,737
4,880,738
4,880,739
4,880,740
4,880,741
4,880,742
4965
4966
4,880,743
4,880,744
4967
4,880,745
4968
4,880,746
4969
4970
4971
4972
4973
4974
4975
4,880,747
4,880,749
4,880,750
4,880,751
4,880,752
4,880,776
4,880,786
4976
4,880,915
4977
4978
4979
4,881,109
4,882,013
4,882,058
4980
4,882,147
4981
4,882,226
4982
4983
4,882,268
4,882,269
4984
4,882,270
4985
4986
4,882,271
4,882,272
4987
4,882,273
4988
4,882,274
Bovine interleukin-1.beta. DNA sequence
Tubeless cell harvester
Biofilter for the treatment of sour water
Process for mild heat treatment of concentrated fluids from
membranes
Process and reagent for the determination of a reaction partner of
an immunological reaction
Process for the rapid determination of sperm cell count and/or
living sperm count
Eukaryotic regulatable transcription
Process for producing antibiotic A47934
Production of uridine
Process for the preparation of L-alpha-amino acid and d-alphaamino acid amide
Production of amino acids using coupled enzyme systems
Method of cultivation of pseudomonas bacteria
Microbial reduction of iron ore
Process for transformation of Yarrowia lipolytica
Prostaglandin biosynthesis inhibitors
Bacterial composition for inhibiting psychrotrophic bacteria in
cream or milk based products
Method of culturing protoplasts
Pseudomonas gladioli and a process for biologically controlling
fusarium diseases using Pseudomonas gladioli pv. gladioli
Streptomycetes plasmid PSG5, a process for obtaining it, and its
use
Fusarium sporotrichioides mutant strain capable of producing both
dideacetylcalonectrin and deacetylcalonectrin
Analytical element and its use in a whole blood hemoglobin assay
Individual-specific antibody identification methods
Immunoglobulin adsorption
Dielectric waveguide sensors and their use in immunoassays
Plasmin A-chain urokinase B-chain hybrid protein
Additive solution for blood preservation and activation
Method for purifying a physiologically active substance produced
by recombinant DNA technique
Sensor using a field effect transistor and method of fabricating the
same
Application of tetrathiafulvalenes in bioelectrochemical processes
Organic waste recycling system and method
Novel polynucleotide analogs, methods for inhibiting nucleic acid
polymerases and methods for inducing synthesis of interferon
Carrier material for use in chromatography or carrying out
enzymatic reactions
Method for determining tissue of origin and degree of malignancy
of tumor cells
Amplified hybridization assay
Monoclonal antibodies to placental isoferritin for use in detecting
oncofetal ferritin associated with breast cancer and Hodgkins
disease
Process for preparation of high molecular weight cell-associated
protein of campylobacter pylori and use for serological detection of
campylobacter pylori infection
High molecular weight kininogen assay
Method of screening microorganisms for the production of
extracellular enzymes
Method for solubilization of low-rank coal using a cell-free
enzymatic system
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4989
4,882,275
4990
4991
4992
4993
4994
4995
4996
4997
4998
4999
5000
5001
5002
5003
5004
5005
5006
5007
5008
5009
4,882,276
4,882,277
4,882,278
4,882,279
4,882,280
4,882,281
4,882,282
4,882,283
4,882,284
4,882,423
4,882,424
4,882,425
4,882,451
4,883,579
4,883,641
4,883,661
4,883,673
4,883,750
4,883,751
4,883,752
5010
5011
5012
4,883,753
4,883,754
4,883,755
5013
5014
4,883,756
4,883,757
5015
5016
5017
5018
5019
4,883,758
4,883,759
4,883,760
4,883,761
4,883,762
5020
5021
5022
5023
5024
5025
5026
5027
4,883,765
4,883,865
4,885,163
4,885,166
4,885,170
4,885,178
4,885,207
4,885,235
5028
5029
5030
5031
4,885,236
4,885,237
4,885,238
4,885,239
5032
4,885,240
Method of purifying endothelial cell growth factors using
immobilized heparin
Process for producing physiologically active substance by
multienzyme process
Continuous process for preparing organic acids by fermentation
Non-toxinogenic vibrio cholerae mutants
Site selective genomic modification of yeast of the genus pichia
Uricase and a method for the preparation thereof
Probe for electrofusion, electroporation, or like procedure
DNA sequences encoding bovine interleukin-2
Heat exchange apparatus
Method for quantitating and differentiating white blood cells
Substance-conjugated complement component C1q
Activation antigen
Receptor specific proteins and their use in receptor typing
Optically active compounds and process for producing thereof
Photoresponsive redox detection and discrimination
Closure and container assembly for biological sterility indicator
Use of arginine as an lymphokine synergist
Method for inhibiting bacterial spoilage and resulting compositions
Detection of specific sequences in nucleic acids
Specific immunoassay for heparin
Method for preparing monoclonal antibody to Hbsag
High-yield methane production process by culture of
Methanobacterium thermoautotrophicum or any other
methanogenic bacterium having the same physiological growth
properties
Bacterial FC receptors
Method of reendothelializing vascular linings
pTN1060, a conjugal plasmid and derivatives thereof that confer
phage resistance to group N streptococci
Bioemulsifier production by Acinetobacter calcoaceticus strains
Biologically pure culture of the microorganism Streptomycas
tropolofaciens used for producing 3,7-dihydroxytropolone and
antitumor use
Fermentation method and apparatus
Device for performing enzyme immunoassays
Pertussis toxin gene: cloning and expression of protective antigen
Stabilized isoenzyme control products
Method for the quantitative determination of lipoprotein
components in a body fluid and method for separating lipoproteins
from blood
Recovery of pres2+s antigen
Topical use of IGF-II for wound healing
Hybrid interferons
Antibiotic A80509
Method of making a soybean protein food product
Biocompatible protein or ligand immobilization system
Method for rapid and sensitive detection of HIV-1 antibodies
Method for determining tissue of origin and presence and extent of
cellular abnormalities
Detection of cellular DNA
Immortalized human bronchial epitherial mesothelial cell lines
Rapid differentiation of bacteria using polyether antibiotics
Use of organic buffers to reduce dehydroascorbic acid interference
in analytical methods
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5033
5034
5035
5036
5037
4,885,241
4,885,242
4,885,243
4,885,244
4,885,245
5038
4,885,246
5039
5040
5041
4,885,247
4,885,248
4,885,249
5042
4,885,250
5043
4,885,251
5044
5045
5046
4,885,252
4,885,253
4,885,256
5047
5048
4,885,358
4,885,359
5049
5050
5051
5052
5053
4,885,696
4,885,697
4,886,593
4,886,655
4,886,664
5054
5055
4,886,673
4,886,740
5056
5057
4,886,741
4,886,742
5058
5059
5060
5061
5062
5063
4,886,743
4,886,744
4,886,745
4,886,746
4,886,747
4,886,748
5064
4,886,749
5065
4,886,750
5066
5067
4,886,751
4,886,752
5068
4,886,754
5069
4,886,755
5070
5071
4,886,756
4,886,757
5072
4,886,758
Ethanol production by zymomonas cultured in yeast-conditioned
media
Genes from pichia histidine pathway and uses thereof
Process for producing A-21978C derivatives
Method of producing hyaluronic acid
Process for producing L-tryptophan
Optically active carbacyclin intermediates and processes for the
preparation thereof
Recovery and purification of lactate salts from whole fermentation
broth by electrodialysis
Transfer vector
Aspergillus niger transformation system
Enzyme immobilization and bioaffinity separations with
perfluorocarbon polymer-based supports
Recombinant DNA expression vectors and DNA compounds which
encode isopenicillin N synthetase
Recombinant DNA expression vectors and DNA compounds that
encode isopenicillin N synthetase from aspergillus nidulans
Universal biological indicator system
Monoclonal antibodies to cholesterol and methods
Monoclonal antibodies specific for synthetic glycosphingolipids
having abnormal branched structure
Method for the purification of LPF-HA
Signal processing method for determining base sequence of
nucleic acid
Method of identifying spectra
Device for destroying bacteria
Method of detecting infection or immunity in ruminants
Low-water-activity inocula for biological control
Method of preserving meat products and microorganisms for the
stabilization of meat products
Enzyme-electrode sensor with organosilane treated membrane
Use of volume exclusion agents for the enhancement of in situ
hybridization
Enzyme immunoassay for detecting HIV antigens in human sera
Diagnostic reagents based on unique sequences within the
variable region of the T cell receptor and uses thereof
Fluorescent conjugates and biological diagnostic assay system
Monoclonal antibody specific for human basal cell surface antigen
Heat-stable, salt-tolerant microbial xanthanase
Nucleic acid encoding TGF-.beta. and its uses
DNA encoding flagellin and vector having the same
Process for producing diadenosine tetraphosphate and derivatives
thereof
Process for the preparation of a pharmaceutically active
compound in a stereospecific form of the formula
Process for the production of ethanol through molasses
fermentation
Microbial production of ultrafine-grained magnetite
Recombinant bateriophage for heterologous cloning of bacillus
microorganisms and method for its production
Preparation of polymeric thiol gels for covalent bonding of
biologically active ligands
Novel restriction endonuclease SplI and process for the production
of the same
Spiramycin resistance-conferring cloning vectors
Method of determining incompatibility-reaction-causing substances
in blood products as well as a method of inactivating said
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5073
4,886,759
5074
4,886,760
5075
5076
4,886,779
4,886,836
5077
4,888,170
5078
5079
5080
5081
4,888,171
4,888,274
4,888,275
4,888,276
5082
5083
5084
5085
5086
4,888,278
4,888,279
4,888,280
4,888,281
4,888,282
5087
4,888,283
5088
4,888,284
5089
4,888,285
5090
4,888,286
5091
4,888,287
5092
5093
5094
5095
5096
4,888,288
4,888,289
4,888,290
4,888,291
4,888,292
5097
4,888,293
5098
5099
5100
5101
5102
4,888,294
4,888,296
4,888,416
4,888,695
4,889,691
5103
4,889,797
5104
4,889,798
5105
4,889,799
5106
4,889,800
5107
5108
5109
4,889,801
4,889,802
4,889,803
incompatibility-reaction-causing substances
Germination floor systems
Stable chemical compositions containing chromogenic materials,
peroxides, and stabilizing chemicals
Inactivation of human immunodeficiency virus (HIV) in proteincontaining solutions by phenols
Activated medium with low non-specific protein adsorption
Vaccines obtained from antigenic gene products of recombinant
genes
Granular product of dried microorganism cells and manufacturing
method therefor
RecA nucleoprotein filament and methods
Diagnosing and monitoring cancer
Method and composition for the diagnosis of Lyme disease
In-situ hybridization to detect nucleic acid sequences in
morphologically intact cells
Novel immunosorbent assays employing antibiotic keying agents
Hybrid proteins produced by an ultrahigh prokaryotic expression
Method of catalyzing chemical reactions
Synthetic gene for acyl carrier protein
Selective inhibitors of benzylaminoxidases with respect to other
aminoxidases
Dipeptidase, its isolation from lactic acid bacteria, antibodies
against the dipeptidase, the use of the dipeptidase and of the
antibodies against it
Enzyme immobilization on a water-insoluble amino groupcontaining carrier
Production of gene and protein analogs through synthetic gene
design using double stranded synthetic oligonucleotides
Rapid differentiation of fungi from bacteria using polyene
antibiotics
Vesicles resistant to enzyme lysis and use thereof in an enzyme
assay
Reagent for determining creatine kinase
Monoclonal antibody specific to HIV antigens
Human epithelium originating from cell cultures
Deodorant and method for preparing and storing same
Adapting bacteria to low pH and high arsenic concentration for use
in oxidizing sulfide ores
Apparatus and method for the continuous cultivation of
microorganisms in a culture liquid
Monoclonal antibodies recognizing L-thyroxine
Method for stabilizing somatotropins
Signal processing method in autoradiography
Modular tissue superfusion chamber
Dry analytical element having a spread control area for assaying
enzyme activity
Heterologous system for the detection of chemically labeled DNA
and other biological materials providing a receptor or target moiety
thereon
Reagent kit producing shortened target DNA segments usable in
sequencing large DNA segments
Synthetic polypeptides and receptor molecules derived therefrom
and methods of use
3.alpha.-hydroxysteroid oxidase and quantitative analysis of
3.alpha.-hydroxysteroid making use of same
Enhanced production of recombinant proteins in myeloma cells
Production of interferon gamma
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5110
4,889,804
5111
5112
4,889,805
4,889,806
5113
5114
4,889,807
4,889,808
5115
4,889,809
5116
5117
5118
5119
5120
5121
5122
5123
4,889,810
4,889,811
4,889,812
4,889,816
4,889,818
4,889,916
4,889,918
4,889,919
5124
5125
5126
4,889,922
4,889,992
RE32,016
5127
5128
RE32,079
RE32,153
5129
5130
RE32,271
RE32,333
5131
5132
5133
5134
RE32,350
RE32,423
RE32,455
RE32,499
5135
RE32,557
5136
RE32,672
5137
5138
5139
RE32,696
RE32,874
RE33,047
5140
RE33,064
Biochemical preparation of alkene derivatives
Continuous process of optimized fermentation for the production of
alcohol
Large DNA cloning system based on yeast artificial chromosomes
Microorganisms of the Phanerochaete chrysosporium strain and
their use
Method of enchancing t-PA and SCU-PA production
Tylosin resistance-conferring gene, designated tlrC, for use in
streptomyces fradiae
Method and compositions for improving the nutritive value of foods
via Lactobacillus Ferementum
Methods for making leather
Bioreactor apparatus
Process and apparatus for carrying out specific binding assays
Purified thermostable enzyme
Protein label and drug delivery system
Protein tokin from bacillus thiringiensis which is toxic to coleoptera
Biologically active PDGF derived A-chain homodimers
Monoclonal antibody specific for human colon fibroblast-derived TPA
Automatic infrared microorganism detection instrument
Analysis of lactic acid or lactate using lactate oxidase
Method and starter compositions for the growth of acid producing
bacteria and bacterial compositions produced thereby
Highly thermostable glucoamylaseand process for its production
Isolation of plasminogen activators useful as therapeutic and
diagnostic agents
A-21978 Antibiotics and process for their production
Thermal convection counter streaming sedimentation and forced
convection galvanization method for controlling the sex of
mammalian offspring
Infectious bronchitis virus strain
A-21978 antibiotics and process for their production
Method for quantitative analysis for limonin
Method of determining pregnanediol in female urine and test
device for use therein
Method for simultaneously cleaning and disinfecting contact
lenses using a mixture of peroxide and proteolytic enzyme
Enzymatic immunological method for determination of antigens
and antibodies
Plasma-free medium for platelet storage
Process for producing a high-purity maltose
Method for the determination of species in solution with an optical
wave-guide
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