Cells: The Basic Units of Life Teacher's Guide 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Cells: The Basic Units of Life Teacher's Guide catalog #2113 Video Produced by ... Chariot Productions Published & Distributed by… AGC/UNITED LEARNING 1560 Sherman Avenue Suite 100 Evanston, IL 60201 1-800-323-9084 24-Hour Fax No. 847-328-6706 Website: http://www.agcunitedlearning.com E-Mail: info@agcunited.com 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com CELLS: THE BASIC UNITS OF LIFE RUNNING TIME: 24 MINUTES PROGRAM SUMMARY This program introduces seventh through ninth grade students to the world of the cell. It is also appropriate for more advanced students because of the depth of the information presented. The first half of the program examines the relationship between cells and living organisms. Examples are provided beginning with the simplest free-living cells of the unicellular bacteria and protozoa up through the complex arrangements of cells that form the tissues of multicellular plants and vertebrate animals. Some history relating to the discovery of cells and the origin of the "Cell Theory" is also presented in this section. The second half of the program is a journey through a typical cell from its nucleus to cell membrane. Each important subcellular structure is identified and its function is described. Animation is used in this section to provide a clear understanding of the relationship between subcellular organelles and specific cell functions. The differences between animal and plant cells are also presented throughout the second part of the program. An optional ten-question Interactive Video Quiz follows the conclusion of this program (the quiz is also provided on Blackine Master 7). Suggestions for its use are given under Teacher Preparation on pages 2 & 3. For your teaching convenience, a script of the video narration is provided in this Teacher's Guide beginning on page 12. 1 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com STUDENT OBJECTIVES After viewing this program and participating in the learning activities, students should be able to… • Describe what cells are. • Name the seven characteristics of all living things. • Name the parts of a cell and describe the function of each part. • Summarize the major differences between the cells of animals and those of plants. • Trace the steps and identify the cell structures involved in the creation, distribution, and export of proteins. SUGGESTED LESSON GUIDE TEACHER PREPARATION 1. Read and review this guide and preview the video before showing it to your class. 2. Read and review the blackline masters and duplicate those you choose to use. 3. NOTE: At the end of this video presentation, there is an Interactive Video Quiz for use in one of several ways: • The quiz is also provided on Blackline Master 7. You can distribute it prior to its presentation on the video and have students answer as the questions are posed. It is your choice as to whether you want them to answer verbally as each question is asked or whether you prefer that each student answer on a sheet of paper. • You may choose to use the Interactive Video Quiz as a study guide. If so, distribute Blackline Master 7 before the viewing with instructions that students read the questions 2 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com first to become familiar with the video content. The students can then be listening for the correct answers during the video presentation. • You could choose to use Blackline Master 7, Interactive Video Quiz, as a review on another day. Note: The Interactive Video Quiz is not intended to be used for evaluation purposes. A 3-part Lesson Quiz is provided on Blackline Masters 8, 9, & 10). 4. Make arrangements to have a VHS player and television set available for use at the time and place selected for viewing. 5. Arrange to have microscopes available for student use. 6. Purchase, or obtain from school collections, the following prepared slides: Allium (onion) root tip mitosis and Basal Ganglion cells stained for the Golgi apparatus. 7. Obtain the living cells of the giant ameba Chaos chaos (Pleomyxa) from a biological supply house. Order these about two weeks before you anticipate using them in class. BLACKLINE MASTER DESCRIPTIONS (An Answer Key for those Blackline Masters that require answers is provided on pages 6, 7, & 8.) Blackline Masters 1 & 2, Vocabulary List, is a list of words used in the video and their definitions. This list can be distributed to the class before the video presentation so students can better understand the terms presented. This list should be retained by students for reference. The list has also been included in this Teacher's Guide on pages 912. Blackline Masters 3 and 3a are diagrams of A Typical Animal Cell. Blackline Masters 4 and 4a are diagrams of A Typical Plant Cell. 3 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Blackline Master 5 is a diagram of Pathways Within the Cell. Blackline Master 6, Crossword Puzzle, gives students an opportunity to use some of the terms introduced in the video. Blackline Master 7, Interactive Video Quiz, is a copy of the questions posed in the interactive video instructional quiz at the end of the video. Suggestions for its use are described under Teacher Preparation on pages 2 & 3. Answers to the quiz are provided on pages 21& 22. Blackline Masters 8, 9, & 10 provide a three-part Lesson Quiz for student evaluation. The EssayQuestions portion of the quiz can be used for extra credit. INTRODUCING THE PROGRAM Introduce this program by telling the students that they are about to enter a very strange and mysterious world--a world that is remote from their day-to-day experience but upon which their lives depend. Let them know that all living things are made up of one or more cells which are so small that one billion average-sized cells could fit into a one cubic inch container. Make the students aware that fully-grown human beings are composed of about one hundred trillion cells of many different types--yet each is capable of living an independent life if provided with the proper environment (such as is possible in the culturing of human cells in vitro). Emphasize that in the tour of the cell they are about to take, they will be looking at life in its most elementary and basic form. Before starting the video, distribute the blackline masters you've chosen to use during the video presentation., e.g. Blackline Masters 1 & 2, Vocabulary List, and Blackline Master 7, Interactive Video Quiz. (Uses for the Interac4 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com tive Video Quiz are described on pages 2 & 3 under Teacher Preparation.) If you've chosen to use the Interactive Video Quiz, you should inform the students that they will be expected to answer the questions which will appear on the screen following the program. VIDEO PRESENTATION Viewing time: 24 minutes FOLLOW-UP ACTIVITIES Discussion 1. Discuss the fact that all living things are made of cells. Ask "What are the characteristics of living things?" Answer: 1) Grow 2) Repair and maintain themselves 3) Reproduce 4) Undergo change 5) Move 6) Respond to surroundings 7) Grow old and die. 2. Discuss the flow of information in the cell from DNA to RNA to protein. Talk about the role of proteins in the body, for example, the hemoglobin of red blood cells, the enzymes that are needed not only to digest food but that are also involved in regulating every biochemical reaction that takes place within the cell, the collagen for connective tissue, the keratin for hair, and the actin and myosin for muscle fiber, etc. 3. Discuss the concept of "one gene/one protein" and contrast to the classical notion of genes (such as the genes for hair color, blood type, etc.) 4. Point out that all of the different types of cells in the body were derived from the single cell of a fertilized egg by the process called cellular differentiation. Speculate as to how, from the point of view of the information contained in the DNA, this differentiation might have occurred. 5. Discuss the cell membrane's role in diffusion, osmosis, active transport, and the uptake of food by phagocytosis and endocytosis. 5 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com 6. Discuss the cell theory of the 19th century. Answers should include: All living things are made up of cells. Cells are the basic structural units of life. All cells come from other cells. Projects 1. Microscopic Examination of Non-Living Cells PLANT CELLS: Have students examine stained and prepared slides of the root tip cells of an onion. Ask them to locate the nucleus, cytoplasm, cell wall, cell membrane, and chromosomes. ANIMAL CELLS: In the trigeminal ganglion cells stained for the Golgi apparatus, locate the nucleus, nucleolus, cytoplasm, Golgi apparatus, and cell membrane. When students have completed these microscopic examinations, discuss the differences between the cells of animals and those of plants. 2. Microscopic Examination of a Living Cell Using the living cells of the giant ameba Chaos chaos (Pleomyxa), locate the vacuoles, pseudopodia, nuclei (this is a multi-nucleate organism), cytoplasm, and cell membrane. A few students may be lucky enough to observe an ameba feeding by phagocytosis or undergoing reproduction by binary fission. Typically, paramecia are also present in cultures of Chaos chaos. Locate their cilia and observe their contractile vacuoles in action under high power. BLACKLINE MASTER ANSWER KEY Blackline Master 3, Crossword Puzzle 6 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Blackline Master 7, Interactive Video Quiz answers can be found on pages 20 & 21 Blackline Master 8, Lesson Quiz, Part 1 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. I J A G F D C E B H Blackline Master 9, Lesson Quiz, Part 2 True Or False 1. F - Some, such as those living in our intestines, are beneficial. 2. T 3. F - The basic principles of that theory are still accepted today. 4. F - They are in continuous motion. 5. T Fill In The Blank 1. cells 2. 1) grow 2) repair and maintain themselves 3) reproduce 4) undergo change 5) move 6) respond to their surroundings 7) grow old and die 3. unicellular 4. multicellular 5. life 7 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Blackline Master 10, Lesson Quiz, Part 3, Essay Questions Answers will vary but should include the following information: 1. Explain how, nearly four hundred years ago, cells came to be named. Almost 400 years ago, while using a simple microscope to study slices of dried plant tissue, the English scientist, Robert Hooke, saw structures that reminded him of the tiny sleeping rooms called "cells" used by monks that he had seen in medieval monasteries. 2. Briefly explain Theodore Schwann's and M. J. Schlieden's "Cell Theory." It consists of three parts: First, that all living things are made up of cells; second, that cells are the basic structural and functional units of life; and third, that all cells come from other cells. 3. Certain differences exist between the structure of animal and plant cells. Write a few paragraphs that compare and contrast animal and plant cells. Very briefly some of the likes and differences in the structure of animal and plant cells… • Plants get their green color from pigment called chlorophyll that is found in special cytoplasmic organelles, called chloroplasts, that are absent in animal cells. • Animal cells possess tiny structures called centrioles, or centrosomes, that are the focal point for the spindle fibers found in dividing animal cells. Plant cells have spindle fibers but rarely have centrioles and are able to reproduce perfectly well without them. • Both animal and plant cells contain large water-filled sacs called vacuoles. • Animal cells, but not plant cells, have many small rounded structures called lysosomes that are very similar to the food vacuoles of protozoa. • Plants possess a tough outer non-living layer called a cell wall, whereas animals lack a cell wall. • Both plants and animals possess a thick cell membrane, also called a plasmalemma or plasma membrane, that is very important to each type of cell. 8 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com VOCABULARY LIST Cell The smallest biological unit capable of carrying out all of the fundamental activities of life. The basic unit of structure and function of any living thing. Cell Membrane The thin, flexible layer that surrounds a cell and which controls all that enters and leaves the cell. Cell Wall In plant and bacterial cells, the outermost nonliving cellulose layer that surrounds the entire cell, including the cell membrane. Centriole In animal cells, a structure outside the nucleus that organizes the spindle fibers during cell reproduction. Centrosome Another name for the centriole. Chlorophyll A green pigment found in the chloroplasts of plant cells that is essential for photosynthesis. Chloroplasts The chlorophyll-containing organelles found in the cytoplasm of plant and algae cells. Chromatin The coils of DNA and protein that condense to form chromosomes. Chromatin can be thought of as chromosomes with no distinct shape. Chromosomes Distinct wormlike cell structures formed from chromatin during cell reproduction. Contractile Vacuoles Large sacs found in the cells of certain protozoans that remove the water that has accumulated inside the cell by pumping it to the outside of the cell. Cilia Hairlike structures found on the outside of certain cells. The protozoans called ciliates use cilia to propel themselves through the water in which they live. Cytoplasm That part of a cell's protoplasm that lies outside of its nucleus. 9 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Deoxyribonucleic Acid (DNA) A large and very complex biochemical that stores the information needed to construct proteins and that carries the genetic information about an organism. DNA The abbreviation for deoxyribonucleic acid. Endoplasmic Reticulum The intricate system of tubes leading from the nuclear membrane into the cytoplasm that is involved in transporting proteins. Enzyme A special class of proteins that control the rates of biochemical reactions. Flagellum A long, whiplike cell structure used to propel sperm cells as well as the cells of the protozoans known as flagellates. Food Vacuoles The sacs where food particles are digested that are found in the cytoplasm of protozoan cells. Gene The basic unit of heredity, made up of a specific region on a DNA molecule. Also a specific region of a DNA molecule that holds the code for one specific protein. Golgi Apparatus A subcellular organelle involved in packaging proteins for export from the cell. Lysosomes In animal cells, the organelles where large food molecules are broken down into smaller, more useful, food molecules. Microtubules Tiny tubules inside the cell that form the cell's internal "cytoskeleton" and that help rearrange structures inside the cell. Mitochondria The organelles known as the "power houses of the cell" where the stored energy of food is made available for use within the cell. Multicellular A word used to describe organisms made up of many cells. 10 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Nuclear Membrane A layer inside the cell that surrounds the nucleus and contains many tiny pores. Nucleus A large structure within the cell that contains chromatin, the nucleolus, and is surrounded by a nuclear membrane. Nucleolus The "little nucleus" found inside the nucleus which is made up of RNA and protein. Organelle A tiny cell structure; a miniature organ. Ribosomes, mitochondria, and chloroplasts are all organelles. Phagocytosis A method by which cells take in food by surrounding and engulfing it. Amebae and white blood cells take in food by this method. Photosynthesis The process by which plant cells make food and oxygen from water, carbon dioxide, and sunlight. Plasma Membrane Another name for the cell membrane. Plasmalemma Another name for the cell membrane. Protein A class of biochemicals made up of amino acids that can be important in building and repairing cells or in controlling chemical reactions inside the cell. Protoplasm All the living materials inside a cell. Ribonucleic Acid (RNA) A class of nucleic acids that can be used either in reading the genetic information on the DNA or in guiding the process of making proteins. Ribosomes The organelles where proteins are assembled. RNA The abbreviation for ribonucleic acid. Spindle Fibers Microtubules visible during cell division that are involved in separating chromosomes into two separate identical groups. 11 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Tissue Layers of closely related cells that work together to perform a specific function, such as muscle tissue, liver tissue, nervous tissue, etc. Unicellular An organism composed of just one cell. SCRIPT OF VIDEO NARRATION CELLS: THE BASIC UNITS OF LIFE Living things, from the simplest microscopic organisms, up through the largest, most complex animals and plants, are alike in one basic respect: All of them are made up of cells. Most cells are so small they can only be seen by looking through a microscope, and, by using powerful electron microscopes, scientists have discovered that these tiny cells are themselves made up of many highly-organized components. All living cells can grow, repair and maintain themselves, reproduce, undergo change, move, respond to their surroundings, and all living cells will eventually grow old and die. Because cells are the smallest biological structures capable of performing all of these life activities, they are called "the basic units of life." In this program, we will learn what cells are, what their components are, and how these components work together to carry out the unique activities of life. UNICELLULAR ORGANISMS Many of nature's simplest creatures are nothing more than single, independently living cells and, therefore, are called "unicellular organisms." By looking at a drop of pond water under a microscope, we can see some of these free-living cells. 12 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com The smallest and most primitive living cells are the bacteria we see here. Some bacterial cells are dangerous to humans and can cause infections, such as strep throat and tuberculosis, while other bacteria, such as those that live in our intestines, are beneficial. Larger and more complicated free-living cells found in a drop of pond water are the protozoa seen here. Protozoan cells come in many different sizes, shapes, and colors. Because they live as independent organisms, many protozoans have developed special cell structures that allow them to move through the water in search of food. The cell of a paramecium is covered with tiny hair-like structures called cilia, which rapidly beat the water, resulting in cell locomotion. An ameba slides over surfaces by extending out parts of its cell, called pseudopods, or false feet, which then pull the rest of the cell along behind them. And this protozoan uses a whip-like flagellum to move its cell through the water. MANY-CELLED ORGANISMS Cells of many protozoans gather together to form colonies of identical cells. The Volvox seen here is one such colony of cells. But in larger, more biologically advanced creatures, called "multicellular organisms," many different kinds of cells are joined together to perform specialized tasks. Generally speaking, the more cells a multicellular organism possesses, the larger its body will be. For example, it 13 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com is estimated that an adult human being is made up of about one hundred trillion cells--whereas a smaller multicellular organism, such as a butterfly, would have only a few billion cells. Within the bodies of multicellular organisms, most cells of the same type will join together to form layers, called tissues. Tissue layers of different cell types can be very clearly seen in this stained section of a frog's stomach. The reddish tissue layer seen here is made up of smooth muscle. These specialized cells are quite long and thin and can contract to help move food down the digestive tract. And these thick rectangular epithelial cells that make up the stomach's lining are specialized to release chemicals into the stomach sac to help digest food. Plants have tissues just like animals do. Here in this section of a plant stem, many distinct layers of cells can be very clearly seen, and they tell an interesting story about how cells were discovered. Almost four hundred years ago, while using a simple microscope like this to study slices of dried plant tissue, the English scientist, Robert Hooke, saw structures that reminded him of the tiny sleeping rooms, called "cells," used by monks that he had seen in medieval monasteries. So it was, through this unlikely connection, that cells, the basic units of life, were named. For over two centuries after their discovery, scientists debated the importance and function of cells. Then, around 1839, two German scientists, Theodore Schwann and M. J. Schlieden, came up with a theory to explain the role of cells in living things. 14 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com The "Cell Theory" of Schlieden and Schwann consists of three parts: First, that all living things are made up of cells; second, that cells are the basic structural and functional units of life; and third, that all cells come from other cells. Today scientists still accept the basic principles of this early nineteenth century theory. And now many wonderful new scientific instruments, especially the electron microscope, have allowed contemporary biologists to probe deeply within cells to unlock some of the mysteries they contain. THE STRUCTURE OF CELLS The basic material of all living cells is a jelly-like substance called protoplasm. The protoplasm of the simplest living creatures, such as bacteria, lacks the complicated structures found in more advanced organisms. But the protoplasm that makes up the cells of fungi, protozoa, plants and animals is divided into two basic parts, easily distinguishable under a light microscope, namely a nucleus and the cytoplasm that surrounds it. Let us look more closely at the cytoplasm and nuclei of some of these more advanced calls. THE NUCLEUS The nucleus is normally an oval or spherical structure found near the center of the cell. The nucleus is very important because it is the control center for the entire cell. The nucleus regulates and directs all of the cell's activities--from how it reproduces to how it uses food. In cells that are not dividing, the interior of the nucleus is filled with threadlike coils called chromatin that is made up of protein and a huge information storage molecule called DNA, short for deoxyribonucleic acid. 15 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Special areas of the giant DNA molecule, called genes, hold the information needed to construct proteins that are used to build and repair cells and are also critical to all normal cell functions. The DNA also carries the hereditary characteristics of a cell. In the case of a unicellular organism, like this paramecium, the genes of its DNA contain all the information needed to make a new paramecium that is an exact copy of the original parent cell. During cell reproduction, when two cells are formed from one cell, the chromatin condenses to form little worm-like structures called chromosomes that, having been duplicated, slide into the newly-forming cells…and then change back into chromatin again. In this way, the hereditary characteristics of the cell are passed from one generation to the next. Inside of the nucleus, along with the chromatin, is a small rounded object called the nucleolus or "little nucleus." The nucleolus is very dense and contains a large amount of a chemical similar to DNA, called RNA, or ribonucleic acid. The special kind of RNA found in the nucleolus, called ribosomal RNA, passes into the cytoplasm through pores in the nuclear membrane that surrounds the nucleus. CYTOPLASMIC CELL STRUCTURES Here in the cytoplasm, the ribosomal RNA forms hundreds of thousands of tiny organs, or organelles, called ribosomes. It is on the surface of the ribosomes that the directions for making new proteins, that arrive from the DNA in the form of another kind of RNA called messenger RNA, are translated as new proteins are formed. 16 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Most, but not all, of the ribosomes in the cytoplasm are found attached to a very complicated system of flattened tubes called the endoplasmic reticulum. The proteins made by the ribosomes in one part of the cell can pass through the tubes of the endoplasmic reticulum on their way to other parts of the cell. Some cells actually export the proteins they make. These types of cells usually have a special system of tubular membranes, called the Golgi apparatus, which seems to be part of the endoplasmic reticulum, and that helps "package" proteins for transport outside of the cell. The Golgi apparatus even works in the opposite direction as it transports substances already inside the cell into the tubes of the endoplasmic reticulum. Spread throughout the cytoplasm are other organelles, much larger than ribosomes, called mitochondria. Some cells, such as human liver cells, may possess a thousand or more mitochondria. The mitochondria are known as the "powerhouses of the cell," for within the tiny folds of these organelles, food materials, like sugars, are converted into special energyrich molecules used by the cell to power its life processes. Because the mitochondria contain a small amount of DNA-enough for about fifty genes--some biologists believe that mitochondria, developed millions of years ago as very simple free-living organism similar to bacteria, invaded other living cells and then took up permanent residence inside of them. PLANT CELLS VERSUS ANIMAL CELLS As might be expected, certain differences exist between the structure of animal and plant cells. Plants get their green color from a pigment called chlorophyll that is found in special cytoplasmic organelles, called 17 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com chloroplasts, that are absent in animal cells. Within the chloroplasts of plants, the energy of the sun is captured as carbon dioxide and water are chemically combined to create sugars and oxygen by a process called photosynthesis. Plants, and animals that eat plants, then use these sugars for food. Like mitochondria, chloroplasts are believed to have developed from simple organisms that took up residence inside of other larger cells. The possibility of such an event occurring is not as unlikely as it might seem. Today single-celled, plant-like algae that can carry out photosynthesis are commonly found dwelling in the cytoplasm of the large cell of the protozoan, called stentor, seen here. These algae presumably escaped being digested to assume a symbiotic relationship with the stentor. As a result of this mutually beneficial relationship, the stentor obtains food and oxygen from the algae in its cytoplasm, and the algae are protected from creatures that might eat them in the outside environment. Another difference between the cells of plants and animals is that animal cells possess tiny structures called centrioles, or centrosomes, that are the focal point for the spindle fibers found in dividing animal cells. Plant cells have spindle fibers but rarely have centrioles and are able to reproduce perfectly well without them. The spindle fibers found in dividing cells attach to the doubled chromosomes and then separate them into two equal groups. Spindle fibers are composed of the microtubules that make up a large part of the cell's cytoskeleton. Microtubules are very important in controlling both the shape and the 18 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com internal arrangement of the organelles within a living cell. Both animal and plant cells also contain large water-filled sacs called vacuoles. Very often, plants will have just one large vacuole…whereas animal cells will usually have several, much smaller, vacuoles. When the vacuoles of plant cells are filled with water, the plant and its leaves will be fairly rigid, but in the absence of water, the vacuoles empty out and the plant wilts. Here we see a contractile vacuole forming in a paramecium cell. These vacuoles slowly fill up with water that accumulates inside the cell and then pump it to the outside. By doing this, contractile vacuoles prevent cells from blowing apart. In this ameba cell, food vacuoles form as pseudopods surround particles of food material in a process called phagocytosis. Digestion takes place inside of these food vacuoles in most unicellular organisms, and after digestion is complete, these vacuoles are filled up with undigested waste that is then released to the outside of the cell. Animal cells, but not plant cells, have many small rounded structures called lysosomes that are very similar to the food vacuoles of protozoa. Lysosomes contain digestive enzymes. Within them large food molecules are broken down into smaller molecules that can then be used by the mitochondria to produce energy for the cell. Lysosomes also help organisms get rid of dead and dying cells. When a tadpole begins to lose its tail as it is transformed into a tail-less adult frog, the lysosomes within the tail cells carry out this job. 19 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com One other major difference between the cells of animals and those of plants is that plants possess a tough outer nonliving layer called a cell wall, whereas animals lack a cell wall. The cell walls of plants join together to create rigid layers allowing trees and other large plants to grow tall and upright. Both plants and animals possess a thin cell membrane, also called a plasmalemma or plasma membrane, that is very important to each type of cell. In plant cells, the cell membrane is found just inside of the cell wall, whereas in animals, the cell membrane creates the outer boundary of each individual cell. The cell membrane is a highly organized structure that performs a number of very important tasks. Everything the cell needs, including food, water, and oxygen, must pass through this membrane to enter the cell. Likewise, waste products exit the cell through this membrane. By controlling what enters and leaves the cell, the cell membrane helps maintain a state of perfect balance within the cell, called homeostasis. In animal and many protozoan cells, the cell membrane also performs the critical role of creating a physical boundary between the delicately balanced internal environment of the cell and the often dangerous, chaotic conditions that can exist outside the cell. Finally, the cell membrane allows the cell itself to be flexible and elastic. This allows the cells of animals and most protozoans to easily change shape, and this is a great help in creating an ease of motion that would be impossible in a rigid organism. 20 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com CONCLUSION In this program, we have been introduced to the world of cells. We have taken a brief look at their most important structures and have learned their primary functions. Yet, many of the biochemical reactions which underlie those cellular functions are complex and not understood by even the most highly trained scientists using the most modern and sophisticated equipment. Still, cell research has shown that all of the structures in normal healthy living cells work harmoniously together performing whatever needs to be done to perpetuate life. Every second of every day, an individual cell performs thousands of incredibly diverse and yet interrelated jobs. And at all times, the internal structures of the cell are in continuous motion--throbbing, moving, breaking apart, coming together, stretching and contracting. In the final analysis, cells can be thought of as marvelous and complex miniature factories whose final product is none other than life itself. VIDEO QUIZ 1. True or False: Cytoplasm is the part of a cell's protoplasm found inside of the nucleus. A. False 2. True or False: The nucleus contains very little of the cell's DNA. A. False 3. True or False: Genes are made up of DNA. A. True 4. These organelles called __________ are where proteins are assembled. A. ribosomes 5. These organelles called __________ are thought of as the "powerhouses of the cell." A. mitochondria 21 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com 6. Layers of identical cells found in most multicellular organisms are called __________. A. tissues 7. The outer, non-living, layer of plant cells is called the _______ ________. A. cell wall 8. Both animal and plant cells contain a thin, flexible layer called the __________ __________ that is very important in controlling what enters and leaves the cell. A. cell membrane (sometimes called the plasma membrane) 9. True or False: Proteins can be packaged for export outside of the cell by a special structure called the Golgi apparatus. A. True 10.Photosynthesis is carried out in these organelles called __________. A. chloroplasts END 22 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com 1 Name _______________________________ CELLS: THE BASIC UNITS OF LIFE VOCABULARY LIST Cell The smallest biological unit capable of carrying out all of the fundamental activities of life. The basic unit of structure and function of any living thing. Cell Membrane The thin, flexible layer that surrounds a cell and which controls all that enters and leaves the cell. Cell Wall In plant and bacterial cells, the outermost non-living cellulose layer that surrounds the entire cell, including the cell membrane. Centriole In animal cells, a structure outside the nucleus that organizes the spindle fibers during cell reproduction. Centrosome Another name for the centriole. Chlorophyll A green pigment found in the chloroplasts of plant cells that is essential for photosynthesis. Chloroplasts The chlorophyll-containing organelles found in the cytoplasm of plant and algae cells. Chromatin The coils of DNA and protein that condense to form chromosomes. Chromatin can be thought of as chromosomes with no distinct shape. Chromosomes Distinct wormlike cell structures formed from chromatin during cell reproduction. Contractile Vacuoles Large sacs found in the cells of certain protozoans that remove the water that has accumulated inside the cell by pumping it to the outside of the cell. Cilia Hairlike structures found on the outside of certain cells. The protozoans called ciliates use cilia to propel themselves through the water in which they live. Cytoplasm That part of a cell's protoplasm that lies outside of its nucleus. Deoxyribonucleic Acid (DNA) A large and very complex biochemical that stores the information needed to construct proteins and that carries the genetic information about an organism. DNA The abbreviation for deoxyribonucleic acid. Endoplasmic Reticulum The intricate system of tubes leading from the nuclear membrane into the cytoplasm that is involved in transporting proteins. Enzyme A special class of proteins that control the rates of biochemical reactions. Flagellum A long, whiplike cell structure used to propel sperm cells as well as the cells of the protozoans known as flagellates. Food Vacuoles The sacs where food particles are digested that are found in the cytoplasm of protozoan cells. Gene The basic unit of heredity, made up of a specific region on a DNA molecule. Also a specific region of a DNA molecule that holds the code for one specific protein. Golgi Apparatus A subcellular organelle involved in packaging proteins for export from the cell. (Continued on Blackline Master 2) ©1994 Chariot Productions Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Name _______________________________ 2 CELLS: THE BASIC UNITS OF LIFE VOCABULARY LIST (Continued from Blackline Master 1) Lysosomes In animal cells, the organelles where large food molecules are broken down into smaller, more useful, food molecules. Microtubules Tiny tubules inside the cell that form the cell's internal "cytoskeleton" and that help rearrange structures inside the cell. Mitochondria The organelles known as the "power houses of the cell" where the stored energy of food is made available for use within the cell. Multicellular A word used to describe organisms made up of many cells. Nuclear Membrane A layer inside the cell that surrounds the nucleus and contains many tiny pores. Nucleus A large structure within the cell that contains chromatin, the nucleolus, and is surrounded by a nuclear membrane. Nucleolus The "little nucleus" found inside the nucleus which is made up of RNA and protein. Organelle A tiny cell structure; a miniature organ. Ribosomes, mitochondria, and chloroplasts are all organelles. Phagocytosis A method by which cells take in food by surrounding and engulfing it. Amebae and white blood cells take in food by this method. Photosynthesis The process by which plant cells make food and oxygen from water, carbon dioxide, and sunlight. Plasma Membrane Another name for the cell membrane. Plasmalemma Another name for the cell membrane. Protein A class of biochemicals made up of amino acids that can be important in building and repairing cells or in controlling chemical reactions inside the cell. Protoplasm All the living materials inside a cell. Ribonucleic Acid (RNA) A class of nucleic acids that can be used either in reading the genetic information on the DNA or in guiding the process of making proteins. Ribosomes The organelles where proteins are assembled. RNA The abbreviation for ribonucleic acid. Spindle Fibers Microtubules visible during cell division that are involved in separating chromosomes into two separate identical groups. Tissue Layers of closely related cells that work together to perform a specific function, such as muscle tissue, liver tissue, nervous tissue, etc. Unicellular An organism composed of just one cell. ©1994 Chariot Productions Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com 3 Name _______________________________ CELLS: THE BASIC UNITS OF LIFE A TYPICAL ANIMAL CELL ©1994 Chariot Productions Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com 3a 11 Name _______________________________ CELLS: THE BASIC UNITS OF LIFE CLOSE-UP OF A TYPICAL ANIMAL CELL ©1994 Chariot Productions Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Name _______________________________ 4 CELLS: THE BASIC UNITS OF LIFE A TYPICAL PLANT CELL ©1994 Chariot Productions Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Name _______________________________ 4a 12 CELLS: THE BASIC UNITS OF LIFE CLOSE-UP OF A TYPICAL PLANT CELL ©1994 Chariot Productions Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com 5 Name _______________________________ CELLS: THE BASIC UNITS OF LIFE PATHWAYS WITHIN THE CELL 1. Chromatin contains DNA instructions for proteins. 4. Enzyme proteins digest food chemicals in the lysosomes. 2. Proteins are made on ribosomes. 5. Food chemicals are converted into energy in the mitochondria. 3. Proteins and protein information travel in the Endoplasmic Reticulum. ©1994 Chariot Productions 6. Cell products, such as some proteins, are packaged for export outside the cell by the Golgi Apparatus. Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Name _______________________________ 6 CELLS: THE BASIC UNITS OF LIFE CROSSWORD PUZZLE 2 1 3 4 8 6 7 5 9 10 11 12 DOWN 1. The basic unit of structure and function of any living thing. 2. The powerhouses of the cell. 3. All the protoplasm outside the nucleus. 4. Layers of closely-related cells that work together to perform specific tasks. 5. The outer, non-living, layer of plant cells. 6. The organelles where proteins are assembled. 7. The thin, flexible layer that surrounds animal cells. ©1994 Chariot Productions ACROSS 1. Wormlike cell structures derived from chromatin during cell reproduction. 3. A structure in animal cells that organizes the spindle fibers during cell reproduction. 5. The organelles of plants where photosynthesis occurs. 6. The abbreviation for ribonucleic acid. 8. A threadlike material of DNA and protein found in the nuclei of non-dividing cells. 9. The organelles in animal cells where large molecules are broken down into smaller molecules. 10. The abbreviation for deoxyribonucleic acid. 11. The cytoplasm's intricate network of tiny tubes is called the __________ reticulum. 12. The __________ apparatus is used to export certain proteins to the outside of the cell. Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com 7 Name _______________________________ CELLS: THE BASIC UNITS OF LIFE INTERACTIVE VIDEO QUIZ 1. True or False: Cytoplasm is the part of a cell's protoplasm found inside of the nucleus. 2. True or False: The nucleus contains very little of the cell's DNA. 3. True or False: Genes are made up of DNA. 4. These organelles called _________________ are where proteins are assembled. 5. These organelles called _________________ are thought of as the "powerhouses of the cell." 6. Layers of identical cells found in most multicellular organisms are called_______ __________. 7. The outer, non-living, layer of plant cells is called the _________ __________. 8. Both animal and plant cells contain a thin, flexible layer called the __________ _____________ that is very important in controlling what enters and leaves the cell. 9. True or False: Proteins can be packaged for export outside the cell by a special structure called the Golgi apparatus. 10.Photosynthesis is carried out in these organelles called _________________. ©1994 Chariot Productions Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Name _______________________________ 8 CELLS: THE BASIC UNITS OF LIFE LESSON QUIZ, PART 1 VOCALULARY WORD MATCH Place the alpha character from the list on the right on the line preceding the matching word on the left. ___ Cell A. Distinct wormlike cell structures formed from chromatin during cell reproduction. ___ Cell Wall B. A class of biochemicals made up of amino acids that can be important in building and repairing cells or in controlling chemical reactions inside the cell. ___ Chromosomes ___ Deoxyribonucleic Acid (DNA) ___ Enzyme ___ Gene C. A large structure within the cell that contains chromatin, the nucleolus, and is surrounded by a nuclear membrane. D. The basic unit of heredity, made up of a specific region on a DNA molecule. Also a specific region of a DNA molecule that holds the code for one specific protein. E. The process by which plant cells make food and oxygen from water, carbon dioxide, and sunlight. ___ Nucleus F. A special class of proteins that control chemical reactions. ___ Photosynthesis ___ Protein G. A large and very complex biochemical that stores the information needed to construct proteins and that carries the genetic information about an organism. ___ Ribonucleic Acid (RNA) H. A class of nucleic acids that can be used either in reading the genetic information on the DNA or in guiding the process of making proteins. I. The basic unit of structure and function of any living thing. The smallest biological unit capable of carrying out all the fundamental activities of life. J. In plant and bacterial cells, the outermost non-living cellulous layer that surrounds the entire cell, including the cell membrane. ©1994 Chariot Productions Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com 9 Name _______________________________ CELLS: THE BASIC UNITS OF LIFE LESSON QUIZ, PART 2 TRUE OR FALSE - Place a T for True and an F for False in the box preceding each statement. 1. All bacterial cells are dangerous to humans. 2. Plants and animals both have tissue. 3. Scientists no longer accept the basic principles of the early 19th century "Cell Theory" of Theodore Schwann and M. J. Schlieden. 4. The internal structures of the cell are at rest at times. 5. Even highly trained scientists using the most modern and sophisticated equipment do not understand many of the complex biochemical reactions which underlie cellular functions. FILL IN THE BLANK 1. Living things are all made up of _________. 2. All living things have 7 characteristics. List at least five of them below. 3. Many of nature's simplest creatures are nothing more than single, independently living cells and are called ______________ organisms. 4. In larger, more biologically advanced creatures called ________________, many different kinds of cells are joined to perform specialized tasks. 5. Cells can be thought of as marvelous and complex miniature factories whose final product is _________. ©1994 Chariot Productions Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com Name _______________________________ 10 CELLS: THE BASIC UNITS OF LIFE LESSON QUIZ, PART 3 ESSAY QUESTIONS. Use the back of this sheet or another sheet of paper if necessary. 1. Explain how, nearly four hundred years ago, cells came to be named. 2. Briefly explain Theodore Schwann's and M. J. Schlieden's "Cell Theory." 3. Certain differences exist between the structure of animal and plant cells. Write a few paragraphs that compare and contrast animal and plant cells. ©1994 Chariot Productions Distributed by AGC/United Learning 1560 Sherman Av., Suite 100 Evanston, IL 60201 1-800-323-9084 Fax 847-328-6706 www.agcunitedlearning.com e-mail: info@agcunited.com