Volume 9 Issue 1 Winter 2015 Aspiration Pneumonia See page 4 Local Regional Anesthesia in the ER See page 8 Case Study: Lameness in a Greyhound See page 12 Message from the Chief Executive Officer Thank You In the past couple months we released our 2014 Annual Report announcing a 7% increase in total patients from the previous year to 13,369 and were recognized with several awards and commendations. We are proud and know that we simply couldn't have accomplished this without you. We were recognized as one of the Top 10 Most Admired Companies in nonprofit category by the Portland Business Journal for the eighth year, recognized as one of the Top Animal Non Profits by the Portland Business Journal, awarded the NW Wild Heritage Award in recognition of our support for the relationship between wildlife and humans by the Wild Artist Guild, and ranked the #1 Emergency Veterinary Hospital by Spot Magazine. As an extension of your practice, we share each of these honors with our referring partners. CEO Ron Morgan The reality of our industry consolidating with increasing competition continues to materialize. We understand you have more options now than ever before for your emergency needs and we are thankful each time you refer your patients to DoveLewis. Your referrals allow us to maintain a fully staffed, state-of-the-art facility available to the community 24 hours per day, every single day of the year. As our annual report illustrated, we put $1,396,735 over the year into our community programs. Our community programs make us a truly unique organization and include one of the region’s largest volunteer-based animal blood banks, a nationally recognized pet loss support program, animal-assisted therapy made possible through a partnership with Guide Dogs for the Blind, stabilizing care for lost, stray, wild and abused animals, education and outreach for veterinary professionals as well as the animal loving community, and financial assistance for qualifying low-income families facing pet emergencies. It is only with your referral support and generous donors that we are able to continue and expand these programs. We are grateful the veterinary community keeps supporting DoveLewis with referrals and recommendations, because without your continued support our community may not have access to our many programs. We rely on referring veterinarians and community supporters to help us keep our doors open. Thank you for trusting us with your patients’ care during animal emergencies. Your confidence and support allows us to continue providing our many unique programs to our community. Message from the Chief Medical Officer Think Positive Lee Herold, DVM, DACVECC Chief Medical Officer Daily affirmations were not invented by the Saturday Night Live character Stuart Smalley; however, this character played by comedian Al Franken popularized - though undoubtedly also mocked - the idea of affirmations. Even if you may not know the origin, I’m sure that most people can recite Stuart’s mantra “I’m good enough, I’m smart enough, and doggone it, people like me.” Did this affirmation play a role in jettisoning this comedian to becoming a two term United States senator? Maybe, though we probably shouldn’t discount his Harvard education. But in all seriousness I do believe the daily intentions that we set, whether that is by way of a positive affirmation or a general positive attitude can greatly direct the course of our day and our life. I have used affirmation as a tool to set a positive intention for myself at times when I felt very bleak about an obstacle. My first experience with affirmation was in the summer of 2006. I was daunted by the task of preparing for my critical care specialty board exams. A trusted advisor, my husband, suggested I use an affirmation. I was skeptical, but what harm could it do? I wrote and recited an affirmation daily, along with a lot of studying for 3 months in preparation for boards. The great news is that I passed boards, but when I look back a more important lesson learned that summer was how to create a positive attitude. Though I will never be an outwardly joyful person, I recognize, admire, and enjoy working with people who are positive and upbeat. Fortunately veterinary medicine draws an abundance of truly joyful people so I have the pleasure to work with many of them. Not being a naturally optimistic person, remaining positive is something that I work on daily - it is a goal that is worth the effort it takes. If you are finding yourself despairing at times, I would suggest emulating the positive people around you, but also maybe letting go of the mocking stereotype of Stuart Smalley and try reciting a daily positive affirmation. 2 VetWrap Volume 9 Issue 1 DVM Outreach Corner One of the best parts of my outreach duties is making personal visits to veterinary clinics. Sometimes I make unannounced, drop-in visits with tasty treats and a referral binder because I know you all have busy schedules. Even when I arrive unannounced I always find there is a team member who is gracious enough to give me a tour of the clinic and go through Ladan Mohammadthe highlights of our information binder. The services Zadeh, DVM, I receive the most positive feedback on are the DACVECC overnight monitoring package and the shuttle service – both the routine transport and the critical transport. If you have not utilized either of these services yet, you may be wondering “are they commonly used?” Well I have answers for you! In 2014 we had a total of 279 patients that stayed with DoveLewis under the overnight monitoring package. 37 of those patients stayed multiple nights after being with their primary care veterinarian during the day. The overnight monitoring package was designed to offer continued overnight care for your stable patients for the affordable price of $220. Common examples of cases that stay here under the overnight monitoring package include stable renal failure patients undergoing fluid diuresis, uncomplicated post operative cases, uncomplicated urinary obstruction cases that have an indwelling urinary catheter in place, and patients with gastroenteritis. Disqualifications include the need for EKG monitoring, oxygen therapy, imaging, frequent blood sugar or blood pressure monitoring, fluid boluses or vasopressor support. The cost does include replacement IV catheter if needed, fluid therapy, routine injectable and oral medications, 12 hours of hospitalization and up to two blood panels performed on our Nova machine which provides electrolytes, BUN, creatinine, blood glucose, ionized calcium, lactate and PCV/TS. As with other referrals, you would call to speak to a staff doctor prior to transfer. You might be surprised which cases can fit into the overnight monitoring package. The van transport is another service we offer that has increased in popularity over the last few years. In 2014 we performed 96 routine shuttle transports and 49 critical transports. A routine shuttle is one where a technician assistant only drives the van to transport a stable patient. One way shuttle cost is $35, round trip is $55. A great way to take advantage of this service is in combination with the overnight monitoring. For $275, we can provide round trip shuttle transport and overnight monitoring. Critical transport utilizes the same van, but a doctor accompanies the patients. This enables us to provide fluids, monitoring, oxygen therapy, and even blood transfusions during the transport. The cost of the critical transport is $225. With both the routine shuttle and critical transport, we do require the owners contact information and permission prior to performing the transport. The van services the greater Portland area. You can find the service area map on our website. As you can see, the overnight monitoring and shuttle service are well utilized. But we always have room for more requests. So if you think you have a stable patient that needs affordable overnight care, or an unstable patient that requires oxygen during transport, please call us to see our services will fit your needs. “The overnight monitoring package provided by Dove Lewis has been a life-saver in more ways than one, for our doctors, clients, and patients of St. Johns Veterinary Clinic. It removes the worry over maintaining the recently unblocked cat, the post-op foreign body dog, or the pancreatitis patient that needs more than 8 hours of IV fluid therapy. What a relief to know that our patients will be monitored and cared for in such good fashion, and return to us with updated progress reports. We value this service greatly, with the peace of mind it has offered over the years. Thank you, Dove!” -Mary Blankevoort, DVM Board of Directors CEO Ron Morgan DoveLewis Emergency Animal Hospital President Katherine Wilson, DVM Forest Heights Veterinary Clinic Immediate Past President Adrianne Fairbanks, DVM Mountain View Veterinary Hospital Vice President Governance & Nominating Chair Carol Opfel, DVM PDX Visiting Vet LLC Secretary Andrew Franklin member at large Finance Chair Sang Ahn, CPA McDonald Jacobs PVMA Representative Lori Gibson, DVM Compassionate Care Home Pet Euthanasia Service, P.C. Medical Advisory Chair Elizabeth Altermatt Herman, DVM Murrayhill Veterinary Hospital Human Resources Chair Scott Bontempo Welsh, Carson, Anderson & Stowe Board Personnel Courtney Anders, DVM Pearl Animal Hospital Julie Poduch Marketing Consultant Michael Remsing Dignified Pet Services Steven Skinner, DVM, DACVIM Oregon Vet Specialty Hospital Kelly Zusman U.S. Department of Justice Thomas Mackowiak, DVM Heartfelt Veterinary Hospital DoveLewis Emergency Animal Hospital is recognized as a charitable organization under Internal Revenue Code, Section 501(c)(3). All donations are tax deductible as allowable by law. Federal Tax ID No. 93–0621534. St. Johns Veterinary Clinic, Portland OR Volume 9 Issue 1 VetWrap 3 CRITICALIST Aspiration Pneumonia Erika Loftin, DVM, DACVECC Aspiration pneumonia is, unfortunately, a frequent occurrence in veterinary patients, and is recognized far more commonly in dogs than in cats. The initial injury (aspiration pneumonitis) actually occurs due to chemical irritation from stomach acid with a high risk for subsequent bacterial infection due to altered microenvironment and potentially aspiration of contaminated liquid and/or pathogenic bacteria in the oropharynx. While minor aspiration events probably occur relatively frequently, normal defense mechanisms (coughing, mucociliary clearance, and the immune system) protect against the development of clinical pneumonia. When these systems are impaired or overwhelmed infection occurs. In some cases, acute respiratory distress syndrome (ARDS) can develop, with a worsening prognosis and often a need for ventilator support. should also be evaluated for the cause of the aspiration event, including megaesophagus, gastrointestinal obstruction or pancreatitis. Figure 1 shows the typical radiographic findings of right cranial lung lobe alveolar infiltrate in a patient with aspiration pneumonia, and Figure 2 shows the same patient 24 hours later. Due to progression of his disease despite aggressive initial therapy and suspected ARDS, this patient required mechanical ventilation and 13 days of ICU hospitalization prior to discharge. A complete blood count (CBC) and chemistry panel are recommended in patients with aspiration pneumonia, but findings are often non-specific. CBC may reveal neutrophilia with a left shift or less commonly neutropenia. A chemistry panel is primarily useful for identifying concurrent or underlying diseases. Additional diagnostic testing should be recommended as indicated based on the specific patient. Tracheal wash with cytology and culture is useful to confirm the diagnosis and identify the organism(s) responsible, which allows for targeted antibiotic therapy. Samples can be obtained via bronchoscopy (with bronchoalveolar lavage) or more commonly via endotracheal or trans-tracheal wash. The use of a deep oral swab (DOS) as a surrogate for tracheal wash (TW) to obtain bacterial cultures was recently investigated (Sumner 2011), and the authors concluded that in adult dogs with aspiration pneumonia, there was partial agreement between tracheal wash culture and deep oral swab culture, and that DOS may represent a reasonable alternative sample in patients that are too unstable for TW. Antibiotic administration can decrease Factors shown to predispose to aspiration pneumonia in veterinary patients include gastrointestinal disease, esophageal disease, neurologic disease, upper airway disease, and recent anesthesia. Male large-breed dogs appear to be predisposed. A recent retrospective multicenter study showed a post-anesthetic aspiration pneumonia incidence of ~0.17%, with significant association with patients that had a regurgitation Figure 1a, 1b - Typical ventrodorsal and left lateral radiographic findings of right episode, and those that received hydromorphone at cranial lung lobe alveolar infiltrate in a patient with aspiration pneumonia. induction (Ovbey 2014). The aspiration event is often unwitnessed and initial clinical signs can be delayed for hours to days. Physical examination findings can include fever, weakness, lethargy, increased respiratory rate and effort, coughing, abnormal lung sounds on auscultation (including crackles and/or dull regions), and nasal discharge. Interestingly, in a recent retrospective study, only about 50% of the patients presented with signs of aspiration pneumonia and 26% actually had normal lung sounds on thoracic auscultation (Tart 2010), so it is important to keep aspiration pneumonia in mind for patients even without specific signs of this disease. The diagnosis of aspiration pneumonia is usually made on the basis of radiographic findings, most commonly a dependent alveolar lung pattern. Other differentials to consider should include infectious bronchopneumonia, hemorrhage, neoplasia, atelectasis, and lung lobe torsion. The right middle lung lobe is the most frequently affected, although the cranial lung lobes are also commonly implicated. When aspiration is suspected, it may be helpful to obtain a left lateral radiograph as this will increase the ability to detect right-sided infiltrates. It is not uncommon for radiographic changes to correlate poorly with the stage and/or severity of disease. Radiographs 4 VetWrap Volume 9 Issue 1 Figure 2a, 2b – Recheck ventrodorsal and right lateral radiographs taken 24 hours later document significant progression in pulmonary pathology, which necessitated mechanical ventilation. Note the changes are far less obvious on the right lateral film than on the left lateral film shown in Figure 1. the yield of bacterial culture, and culture samples should ideally be obtained prior to initiation of antibiotic therapy. A variety of bacteria can be found in respiratory cultures, with Escherichia coli and Pasturella typically the most common. Other pathogenic respiratory bacteria include Staphylococcus, Mycoplasma, Klebsiella, Pseudomonas, Enterococcus, and Streptococcus species. Polymicrobial cultures are relatively common, likely due to aspiration of oropharyngeal and/or enteric bacteria. A recent study (Epstein 2010) demonstrated that patients with more severe respiratory signs (respiratory failure requiring ventilator support) had a higher incidence of antimicrobial resistance on bacterial cultures, suggesting that these patients should probably be started on more aggressive antibiotic regimens pending culture results. In this patient population, 98% of the bacteria cultured were susceptible to amikacin and 91% were susceptible to imipenem, as compared to only 35% susceptible to amoxicillin-clavulonate and 48% susceptible to enrofloxacin. Another recent study (Proulx 2014) showed that 26% of patients with bacterial pneumonia that had a respiratory culture performed had at least 1 bacterial isolate that was resistant to the empirically selected antimicrobials. The incidence was even higher (57%) in patients that had received antibiotics over the preceding 4 weeks. This suggests that airway cultures should be routinely recommended, and that care should be taken to select different antibiotics in patients that have recently undergone treatment. pneumonia. It has been suggested that movement of colloid molecules across the damaged alveolar endothelium may lead to increased interstitial fluid accumulation. However, it is also possible that the more critically ill patients were more likely to receive colloids and that there is not a causative link. Respiratory physiotherapy 2-4 times daily is helpful to mobilize and eliminate respiratory secretions in patients with pneumonia. In veterinary patients, this is most commonly provided as nebulization (instillation of very small water droplets capable of reaching the lower airways) and coupage (rhythmic clapping against the sides of the thorax to stimulate coughing). While studies are equivocal on the benefits of this practice, it is commonly recommended in veterinary patients. No benefit has been shown to nebulization of antibiotics, and this can cause airway irritation and inconsistent antibiotic delivery due to poor lung penetration. Empiric antibiotic therapy should be started pending bacterial culture results, or when airway sampling is not feasible due to patient stability or financial constraints. Cytology can be evaluated quickly in hospital, and can help guide selection. In stable patients with mild clinical signs, monotherapy with amoxicillin-clavulanic acid may be adequate. Patients that are more clinically compromised should be treated with combination therapy (such as a potentiated penicillin along with either a fluoroquinolone or an aminoglycoside). Alternative antibiotic strategies may be necessary in patients that are not showing a good clinical response, patients that have been on recent antibacterial therapy, or based on known hospital bacterial populations and resistance patterns. The need for oxygen supplementation is determined by both subjective and objective means. Pulse oximetry (SpO2) measurements assess the percentage of hemoglobin saturation with oxygen and can be obtained non-invasively, but can be difficult to measure in non-compliant patients, those with pigmented mucous membranes, and those with arrhythmias. In general, patients with SpO2 <95% will benefit from supplementation oxygen. Arterial blood gas measurement is a more accurate assessment of oxygenation, but is also more invasive and requires specialized equipment. Subjective evaluation of the respiratory status of the patient can also be useful, and includes monitoring respiratory rate and effort, as well as observing appetite and ability to rest. Oxygen supplementation can be provided in a variety of ways, including an oxygen cage, oxygen mask, nasal prongs or tubes, an oxygen “hood” constructed from a covered E-collar, and via endotracheal tube. Oxygen supplementation is typically at ~40% initially, but can be provided at higher concentrations depending on the method and patient requirements. Oxygen supplementation at high concentrations (60% or above) can cause toxicity due to free radical accumulation, and use should ideally be limited to 24 hours or less. Patients with severe respiratory impairment may require mechanical ventilation. Some patients with aspiration pneumonia do not require hospitalization, and can be managed with oral antibiotics. Radiographs should be monitored serially to help determine response to therapy, and duration of antibiotic treatment should ideally continue for 2 weeks past clinical and radiographic resolution of disease. Many patients are sick enough that they require hospitalization for supportive care. Fluid therapy should be used as needed to maintain hydration and perfusion, and febrile patients in particular can have increased insensible losses and easily become dehydrated. However, excessive administration of intravenous fluids should be avoided as pulmonary capillaries may have increased permeability due to the acute inflammatory response; this can lead to interstitial edema and worsening hypoxemia. This risk is higher in patients with cardiac disease. Patients with sepsis may require vasopressor support to help maintain perfusion. A recent retrospective study (Tart 2010) identified colloid therapy as a negative prognostic indicator in patients with aspiration Bronchodilators such as terbutaline or theophylline are sometimes used in patients with aspiration pneumonia, and can theoretically be useful in ameliorating the bronchospasm that can accompany chemical injury to the airways. However, bronchodilators can potentially impede the cough reflex and also worsen hypoxemia by opening airways that lead to diseased alveoli and increasing dead-space ventilation. Recent human ARDS trials have not shown any improvement with bronchodilator therapy. While glucocorticoids could theoretically be beneficial to reduce pulmonary inflammation, they are also immunosuppressive which can be deleterious in the face of bacterial infection. Glucocorticoids are likely only indicated in the presence of concurrent inflammatory lung disease, with upper airway swelling, and with hypoadrenocorticism or other concurrent steroid-responsive conditions. Cough suppressants are generally contraindicated in aspiration pneumonia as they can impair clearance of respiratory secretions. In some cases, oral or intravenous N-acetylcysteine Continued on page 6 Volume 9 Issue 1 VetWrap 5 Continued from page 5 (mucomyst) may be useful as a mucolytic, but this medication should not be nebulized due to airway irritation and bronchospasm. Furosemide should not be used as it can result in drying and trapping of infectious debris in the lower airways. Preventive measures are very important, especially in patients that have known risk factors for aspiration. Rapid induction and endotracheal intubation is critical for patients undergoing general anesthesia, particularly those that have not been appropriately fasted. Some references have suggested that increasing gastric pH via administration of H2 blockers or proton pump inhibitors can decrease risk of airway acid injury in the event of aspiration, while others have shown increased risk of bacterial pulmonary infection in human patients that are on these medications. Use of a prokinetic such as metoclopramide has been shown to decrease risk of aspiration in humans when given 12 hours prior as well as on the day of anesthesia. If regurgitation occurs in an anesthetized patient, care should be taken to swab or suction the oral cavity, and it may be indicated to remove the endotracheal tube with the cuff still partially inflated. These patients should also be monitored very closely for signs of pneumonia. Patients receiving enteral nutritional support are also considered at increased risk of aspiration pneumonia, as well as those with decreased gag reflex, diseases causing dysphagia, and decreased mentation. Patients with laryngeal paralysis (with or without arytenoid lateralization surgery) have an increased risk of aspiration pneumonia. With rapid recognition and treatment, the prognosis for aspiration pneumonia is relatively good. A recent retrospective study (Tart 2010) showed a survival rate of approximately 82% in patients treated for aspiration pneumonia. A statistically significant association was documented between number of lung lobes affected radiographically, and survival. No prognostic difference was found among patients based on signalment, culture results or specific treatment protocol. Suggested Reading RADLAB Radiology Case Study Alan Lipman, DVM, DACVR An 8 year old Springer Spaniel presented with a 48 hour history of lethargy and vomiting. Physical examination determined the patient had a distended, tense abdomen and was mildly dehydrated. Abdominal radiographs were performed and a lateral view of the abdomen is included for evaluation. Describe significant radiographic findings and list possible differential diagnoses. Please determine what additional diagnostic imaging may be useful. Continued on page 11 Radiology Services OUTPATIENT SERVICES & FEES Radiographs (two views and interpretation; no exam). .......................$235.00 Radiograph Interpretation (per case).................................................$37.00 Interpretation of digital or plain films by Dr. Lipman Abdominal Ultrasound.......................................................................$330.00 Second Cavity Ultrasound (same patient)........................................$170.00 Dear JD. Bacterial pneumonia in dogs and cats. Vet Clin North Am Small Anim Pract. 2014;44(1):143-159. Echo / Single Organ Ultrasound.......................................................$265.00 Epstein SE, Mellema MS, Hopper K. Airway microbial culture and susceptibility patterns in dogs and cats with respiratory disease of varying severity. J Vet Emerg Crit Care 2010;20(6):587-594. Ultrasound–guided Fluid Drainage*................................................$240.00 Kogan DA, Johnson LR, Sturges BK, Jandrey KE, and Pollard RE. Etiology and clinical outcome in dogs with aspiration pneumonia: 88 cases (2004-2006). J Am Vet Med Assoc 2008;233:1748-1755. Ultrasound–guided FNA*..................................................................$100.00 Ultrasound–guided Fluid Aspirate*................................................. $50.00 Ultrasound–guided Cystocentesis*................................................. $40.00 *All Ultrasound-guided procedure pricing does not include sedation if necessary CT of Chest, Abdomen, Nasal or Brain............................................$ 879.00 Ovbey DH, Wilson DV, Bednarski RM, Hauptman JG, Stanley BJ, Radlinsky MG, Larenza MP, Pypendop BH, Rezende ML. Prevalence and risk factors for canine postanesthetic aspiration pneumonia (1999-2009): a multicenter study. Vet Anaesth Analg 2014;41(2):127-136. (includes contrast, anesthesia & exam fee) Proulx A, Hume DZ, Drobatz KJ, Reineke EL. In vitro bacterial isolate susceptibility to empirically selected antimicrobials in 111 dogs with bacterial pneumonia. J Vet Emerg Crit Care 2014;24(2):194-200. CT Ortho additional study (same visit). ............................................$ 625.00 CT Lung Met Check (includes anesthesia and exam). .......................$379.00 Sumner CM, Rozanski EA, Sharp CR, Shaw SP. The use of deep oral swabs as a surrogate for transoral tracheal wash to obtain bacterial cultures in dogs with pneumonia. J Vet Emerg Crit Care 2011;21(5):515-520. Dr. Alan Lipman, DVM, DACVR Phone: 971.255.5964 Diagnostic Imaging Coordinator: Katie Olsen, CVT Phone: 971.255.5964 Tart KM, Babski DM, Lee JA. Potential risks, prognostic indicators, and diagnostic and treatment modalities affecting survival in dogs with presumptive aspiration pneumonia: 125 cases (2005-2008). J Vet Emerg Crit Care 2010;20(3):319-329. 6 VetWrap Volume 9 Issue 1 CT additional study (same visit).........................................................$325.00 CT Orthopedic (includes contrast, anesthesia & exam fee)................$914.00 Phone consultations are welcomed! DoveLewis Education & Outreach Program Third Thursday Rounds Continuing Education We invite all doctors and support staff in the community to attend our free Third Thursday Rounds. Rounds cover all topics in veterinary medicine. For more information on topics and registration visit dovelewis.org/third-thursday-rounds. Focused on business. Passionate about community. Pacific Continental Bank proudly supports DoveLewis Emergency Animal Hospital. 503-350-1205 therightbank.com Experience you can trust to care for your patients overnight. TECHNICIAN LECTURES BROUGHT TO YOU IN PARTNERSHIP WITH s “Thank you for alway zed, emphasizing organi ning, consistent staff trai development and skills acquisition.” d., -Liz Hughston, ME VTS (SAIM, ECC) RV T, CV T, Dove overnight monitoring includes exam, ER or ICU monitoring as determined by a DoveLewis veterinarian with fluids, pain management—antibiotics, or oral medications as prescribed by the referring veterinarian (if indicated) and patient status lab work (if necessary). The medical team at Frontier Veterinary Hospital is so thankful and appreciative of Dove’s overnight monitoring package and their shuttle service. We have utilized both services many times. It is such a relief to be able to send over our stable post-operative/milder medical patients and know that we don’t have to worry about them at home overnight – essentially the overnight monitoring package is an extension of our hospital’s continued care... Thank you, Dove! -Lisa Yung, DVM main 503.228.7281 • backline 971.255.5990 • fax 503.228.0464 Volume 9 Issue 1 VetWrap 7 DVM Block Party: Local Regional Anesthesia in the ER Josh Cruz, DVM If pain control was a party, the opioids, NSAIDs, and neuromodulating therapies would be the most glamorous and gregarious attendees. But sometimes a very effective member of the party is the often forgot wallflower, the local regional block. Local regional anesthesia, or local blocks, is an essential component to managing pain in a wide variety of our patients in the emergency and critical care setting. Of course, the primary goal of these blocks is to provide relief from current painful stimuli, or to prevent the sensation of pain caused by our own intervention. A local block’s use, however, extends beyond this simple classification. Allowing for the minimization of other analgesics and sedatives, ease of administration with minimal risk, and overall cost effectiveness, make local anesthesia one of the more interesting and useful characters at this party. Understanding basic nerve anatomy and physiology is essential for understanding how local anesthesia works. Rapid changes to an electrical gradient across nerve membranes allows for transmission of various signals (pain, sensation, motor) through nerve fibers. These action potentials of electrical energy are typically managed by sodium gated channels. Local blocks utilize these channels to inhibit propagation of nerve signals, hence, anesthesia. At greater doses of blockade, not only pain sensation but motor function may be inhibited. While the basic function is similar among local anesthetics, there are many local anesthetics that vary in duration and strength of action, positive/negative side effects, and motor and sensory blockade. Lidocaine and bupivacaine are the most notable and widely used sodium channel blockers in the ER/ICU setting, and will be the focus of this article. Many local regional anesthesia dose variations and recipes involving lidocaine/bupivacaine have been described in 8 VetWrap Volume 9 Issue 1 veterinary medicine. Combining both shorter acting lidocaine with longer acting bupivacaine is often used. Mixing local blocks with sodium bicarbonate, in an attempt to minimize patient discomfort and increase onset of anesthesia is still controversial. Mixing with a vasoconstrictor (epinephrine) has also been used to prolong duration of analgesia, but may alter regional pH limiting clinical benefit. Opioids, alpha-2 agonists, and NMDA antagonists (ketamine) have also been used in conjunction with sodium channel blockade to achieve regional anesthesia. Ultimately it is difficult to determine the effectiveness and benefit of adjunctive mixtures to the primary sodium channel blockage anesthetics. Often in the emergency setting, keeping it simple is often the best. Patient selection and reason for anesthesia should help guide your choice but there is nothing wrong with one drug selection for local blocks. Various complications exist with performing local blocks. These complications are usually rare. With appropriate dose, technique, and patient selection, complications become insignificant. Systemic absorption and subsequent side effects to the cardiovascular and central nervous systems are definitely possible, but using appropriate drug volumes and understanding species difference should help prevent this complication. Injection at any site that may already be compromised from severe trauma or infection should not be performed. Moving the injection site further up the neurologic pathway, or increasing the circumference of the block, may be reasonable options assuming safety of injection and dosage is still appropriate. Hemorrhage is always a concern, but understanding landmarks, knowing rough location of major vessels, and aspirating back prior to injection will help prevent this complication. Also having a good understanding of patient systemic health is essential (eg. coagulation parameters, drug sensitivities, and concurrent medications). Reconsider performing local anesthesia on patients with coagulopathies and thrombocytopathies. Nerve trauma is of course possible, but less likely in the majority of blocks performed in the ER. Local Block Techniques The following are four of my favorite, and most commonly used local blocks. This is meant to be a quick guideline, for a more in depth anatomy and description, other resources should be consulted. The techniques described below are by no means meant to be all inclusive. Dental, topical, intraarticular, testicular, ring, epidural, and brachial plexus (all-time favorite) blocks are all useful, but usually used preemptively prior to more advanced surgery or painful stimuli, and not as practical in the ER setting. As with all blocks, calculating total doses prior to injection, site preparation (clip/scrub), aseptic technique (sterile gloves, needles), and aspirating prior to injection is essential. Incisional Line Block Sacrococcygeal Block Retrobulbar Block The most commonly used block in the ER. One of the biggest perceived failures of this block is its failure to work adequately. Ensuring accurate dosage and allowing time to pass (>5 minutes) is essential. Most traumatic wounds requiring local regional anesthesia typically also require thorough hair clipping, cleaning, and flushing. Usually by performing a local block prior to final wound cleaning, but well before induced injury, you are able to give enough time to allow complete anesthesia to occur. Also remember to block those areas not near the wound site but near areas of future pain (i.e. drain placement). While typically associated with male feline urinary catheter placement, any procedure in which caudal pudendal and tail anesthesia is required could make use of this block. This block is only recently described and further investigation into its effectiveness is warranted. However, it has been used effectively, and for some cases, allowing urinary catheterization without use of general anesthesia. Because of this, assuming the patient already has systemic analgesia and sedation, a sacrococcygeal block is attempted on the majority of my patients in which a urinary catheter needs to be placed. Depending on block’s effectiveness, you can either move on towards catheterization or general anesthesia if needed. In the ER setting, the retrobulbar block is typically performed prior to enucleation post traumatic proptosis. Patient selection is essential in deciding whether to perform this block, and controversy still exists regarding the preferred technique and overall effectiveness. Traumatized anatomy, increased vagal tone, and unseen bacterial contamination may lead to increased procedural risks. Also due to its location, the risk for injury and systemic/ CNS absorption is higher. Regardless, this block can still be used to good effect and should be considered. Intrapleural/ Intercostal Block An easy, often underutilized option for analgesia in critical patients suffering from pancreatitis, painful pleural space disease, or diaphragmatic disease is the intrapleural/intercostal block. Many patients already on systemic multimodal analgesia that still exhibit refractory pain may see dramatic benefit from these blocks. For most of the pain expected in these patients, initial administration of lidocaine, followed by bupivacaine should be performed. Hopefully after reading this, if you are new to local blocks you will be more comfortable performing these various techniques. If you are already well versed in local blocks, let this be a gentle reminder. I like to think that if it is painful, and I can get close to or around the nerves responsible for the pain with a needle, local regional anesthesia should be considered. Remember, sometimes even the wallflower has something to add. After all, everyone is invited to a block party. Technique Dosage Description Comments Incisional Line Lidocaine 2% 2-4 mg/kg Bupivacaine 0.5%: 1-2 mg/kg 25 or 22 gauge needle. Dilute with saline as needed for volume, or 0.3mls of sodium bicarbonate per 10 mls. Sacrococcygeal Lidocaine 2%: 0.25-0.5 mls 25 gauge needle inserted 30-45 degrees into most mobile joint caudal to sacrum. Sacrococcygeal joint, or first 2 coccygeal joints are acceptable. Feel for “pop”. Retrobulbar Lidocaine 2%: 1-2mls 22 gauge 1.5 inch needle. Bent at middle 20 degrees, inserted at midline or just lateral to midline under inferior eyelid. Aim slightly dorsally and nasally after initial insertion about 1-2 cm. Feel for “pop”. Intrapleural Lidocaine 2%: 1.5mls/kg, followed by bupivacaine 0.5%: 1.5mls/kg Injected at middle of 9th rib space. 25 to 22 gauge needle in small patients. 22 gauge 1.5 inch needle for larger patients. Block can be instilled into chest tubes, but will likely need saline as flush down tube. Volume 9 Issue 1 VetWrap 9 COMMUNITY PROGRAM When to Say ‘Goodbye’ A discussion with Ron Morgan & Enid Traisman, M.S.W., CT With so many great community programs at DoveLewis, it was hard to choose just one to write about. But it was my recent experience saying goodbye to our pug, Lucy, which led me to our Pet Loss Support Program. I asked our Director of the program, Enid Traisman, certified grief counselor, to help co-write this article. Lucy Morgan Ron: I work in a building where end of life for animals is, unfortunately, sometimes a reality. We see pet parents struggle with the decision to euthanize their beloved companion animals. Whether their pet has been battling a disease for years or suffered a recent injury, it is never easy. But when is it time to say ‘goodbye’? Medically, we can discuss all the statistics, survival rates, treatment options and pain the pet is experiencing. But the decision is ultimately in the pet parents’ hands, and what it really comes down to is the human-animal bond and quality of life. Enid, many of us have experienced having to make this decision, sometimes more than once - what is it that makes it so difficult for us to decide when to say ‘goodbye’? Enid: It is unfortunate that our companion animal life spans are not as long as ours, thus many of us who share that special bond are faced with very difficult end-of-life issues. Judging whether or not to euthanize a beloved pet can be among life’s most difficult decisions. When faced with this, people often feel that they have been put unfairly in a God-like position, having to decide between life and death for someone they love and for whom they are responsible. As compassionate guardians we are also very concerned about whether our animal is suffering or has lost quality of life. Ron: With more than a decade as the CEO of an emergency veterinary hospital, I still struggle just as others do when facing my pet’s life coming to a close. Our dearest Lucy, whom many of you saw in the last issue of VetWrap and on Twitter if you are following me, had been living with diabetes for almost 5 years. The reality is DoveLewis was able to give us so much more time with her than we imagined after learning of her diabetes and we are grateful for that. But as a family, we started talking about euthanasia after many hospital visits and even more so after diabetes took her vision. The dialogue that each person will have with themselves and their family will likely center around quality of life, as did my own. What guidance can you provide for pet parents having to make this decision? Enid: Many people ask me how they will know if it is time to choose euthanasia for their beloved companion animal. The term “euthanasia” means “the good death,” a death without pain or suffering. To choose this for a pet is both an honor and a burden. I tell them to first consult with their veterinary professional about prognosis and then to trust their hearts and intuition which is based on the bond they share and the unspoken communication they have with their pet. I tell them to talk about it with themselves, their family and friends. And as difficult as it is, it’s important for them to express their feelings, observations and philosophies about quality of life. Continuing to do this until they come to a decision or identify a “signal’ from their pet letting them know it is time can be helpful in making this tough decision. It is important to note that quality of life is interpreted uniquely by each individual. For some folks, any life is life. For others, if their pet can no longer enjoy his or her normal activities, quality of life has been lost. There is no right or wrong answer; everyone has a unique perspective. Ron: When we came to the hard decision in December to let Lucy go run somewhere that she could see again and feel no pain for the first time in a long time, we knew it was the right thing to do, the selfless thing to do. Just as my family did, there are so many emotions that people will go through. Tell us about the emotional response and what people can do after you have made this tough decision to say goodbye. Enid: In pet loss groups, we often discuss the ‘5 stages of grief’. Specifically, when euthanasia was involved, we often discuss feelings of guilt, which I describe as anger turned inward. This is a normal part of the grieving process. We do this because in loving and grieving our pets, we wish we could have done more, or wish we did not have to choose euthanasia. Working toward forgiving ourselves is essential. Releasing the guilt doesn’t mean that we don’t/didn’t care for our pet; instead it will allow us to freely tap into all the wonderful memories of a lifetime shared. But please know that whenever your clients make this tough decision, we are here for them. The Pet Loss Support Program offers guidance and healing opportunities to those who have said ‘goodbye’ to their beloved pets. 10 VetWrap Volume 9 Issue 1 Reward Theory { Education rewards everyone it touches } CE should reward not only you, but also your patients, clients and practice. So the IDEXX Learning Center provides a comprehensive curriculum. And learning options that’ll have every member of your team wagging their tail: the veterinarian who wants to learn from experts face-to-face, techs who love the convenience of online courses, and the practice manager who’s eager to have protocols communicated consistently across the practice—and with clients. To turn theory into reality, visit idexxlearningcenter.com. Knowledge you can put into practice™ IDEXX Learning Center © 2011 IDEXX Laboratories, Inc. All rights reserved. • 9304-00 • All ®/TM marks are owned by IDEXX Laboratories, Inc. or its affiliates in the United States and/or other countries. The IDEXX Privacy Policy is available at idexx.com. RADLAB Radiology Diagnosis Continued from page 6 There is increased soft tissue opacity within the dorsal to mid abdomen which is displacing the colon ventrally adjacent to the urinary bladder. There is a loss of serosal margin detail within the retroperitoneal space with a lack of visualization of the kidneys and normal retroperitoneal fat. The increased opacity within this portion of the abdomen has a wispy, streaking appearance. These findings are consistent with retroperitoneal effusion. No gross evidence of peritoneal effusion is identified. Differential diagnoses for retroperitoneal effusion include retroperitoneal hemorrhage secondary to a bleeding mass, trauma or coagulopathy, urinary tract leakage, or less likely a purulent exudate. Abdominal ultrasound may be useful to evaluate for a neoplastic process involving the retroperitoneal space (most likely involving kidneys or adrenal glands). Definitive diagnosis of urinary tract rupture would require excretory urography or surgical exploratory. Abdominal ultrasound was performed which demonstrated retroperitoneal effusion, large bilateral adrenal masses with invasion of the right adrenal mass into the caudal vena cava (image included) as well as suspected metastatic nodules involving the cortices of both kidneys. Differential diagnoses for the adrenal tumors included adenocarcinoma, pheochromocytoma and hemangiosarcoma given the large size of the masses and aggressive vascular invasion of the caudal vena cava. Volume 9 Issue 1 VetWrap 11 SURGICAL Lameness in a Greyhound Coby Richter, DVM, DACVS Zoe, a 6 year old female spayed greyhound presented on emergency following a witnessed accident earlier that day. While exercising at a park, the dog tripped going down concrete stairs resulting in laceration and abrasions to both rear limbs. She was otherwise in good health, current on vaccination and preventive veterinary care, and had no history of lameness. Zoe is a retired racing dog with an unknown history of injury or reason for retirement. At the initial outpatient visit, Zoe’s laceration and abrasions (over both left and right metatarsals) were treated with standard wound care and bandaging. The dog was most sensitive to palpation of the left rear limb but did not show lameness at a walk or trot in the hospital. She was discharged on oral antibiotics and pain medications with a plan for a recheck evaluation with her primary care DVM. Two weeks following the initial trauma, the owner noticed a consistent lameness in the left forelimb. Zoe had been on exercise restriction since the first tripping incident and the owner was not aware of any trauma that could have resulted in front limb lameness. At the primary care veterinary clinic, a lameness exam showed a consistent left front lameness but no soft tissue swelling or joint effusion. The only pain localization was upon squeezing the nail of the 4th digit. Radiographs were taken of the forelimb (Figure 1) with the primary significant finding being an absence of the distal end of P3 of the 4th digit. Full bloodwork was collected at that time showing mild elevation in HCT 64%, lipase 759 (138-755), albumin 4.0 (2.7-3.9), glucose 118 (63-114), phosphorus 2.4 (2.5-6.1), creatinine 1.6 (0.51.5) and BUN of 19 (9-31). acute-on-chronic injury to the digit was also possible. Infection was considered less likely with the total lack of soft tissue involvement, normal white cell count and normothermia. Injury at the time of the park stair incident is also possible, potentially obscured by the more obvious and painful soft tissue trauma to both rear limbs. Options discussed at that time included toe amputation, survey radiographs of thorax and longbones, oncology referral and continued medical management. The owner elected to try nonsteroidal anti-inflammatory medication and continue monitoring. Zoe was started on carprofen (0.9mg/ kg PO BID) and continued exercise restriction. A recheck evaluation three weeks later showed a left forelimb lameness of 2-3/5 in the left forelimb with soft tissue swelling centered at the distal interphalangeal joint (Figure 2). The owner reported that lameness improved on carprofen, but never completely resolved. The dog was doing well otherwise. Biopsy (incisional or needle) was discussed but was not felt to be likely to produce a diagnosis with less than an excision procedure (amputation). Furthermore, amputation was considered likely to be central to the treatment plan regardless of diagnosis. The owner elected digit amputation at that time. Zoe was anesthetized in a routine manner and the 4th digit amputated at the proximal interphalangeal joint. The entire resected segment was placed in formalin for submission. Zoe was recovered in a spoon splint to protect the surgical site. She was managed in a splint for one week, then a simple foot bandage for an additional two weeks. At the two week recheck and suture removal, Zoe showed no lameness in the left forelimb. The foot was bandaged to protect the delicate skin for a final week. The initial histopathology of the soft tissues indicated mild reactive fibroplasia with mild mastocytic and neutrophilic inflammation. Decalcification and histopathology of the digit followed revealing an expansile mass that arose from the nailbed epithelium and was compressing the underlying third phalanx. The final diagnosis was a nailbed keratoacanthoma; completely excised. Zoe was started on tramadol and referred to DoveLewis for surgical consult. The owner reported that there was no perceptible change in lameness over the four days on tramadol (3mg/kg PO TID). Upon presentation, Zoe was grade 3/5 lame in the left forelimb. There was no palpable or visible soft tissue swelling, joint effusion or crepitus. Full range of motion was possible in all joints (including digits) without evidence of pain. Similar to the referring DVM visit of the previous week, the only pain localization was when the nail of the 4th digit was squeezed. All toenails were long but otherwise unremarkable. The abrasions and laceration from the original trauma 2.5 weeks earlier had healed well. Subungual (nailbed) neoplasia is relatively common in the dog, however keratoacanthoma is one of the more rare diagnoses in this group. Squamous cell carcinomas represent 30-50% of subungual tumors, followed by malignant melanoma, osteosarcoma, soft tissue sarcomas and mast cell tumors. Subungual SCC is locally invasive and has a low metastatic potential. Regional lymph node or distant metastasis after excision to the level of P1 has been reported in 10-30% of cases. Subungual melanomas develop distant metastasis (lymph nodes, lungs, other systemic sites) in approximately 30-50% of cases. Prognosis following complete excision of a subungual melanoma is fair to guarded. Soft tissue sarcomas of the nailbed are typically locally aggressive. Approximately 75% of nailbed tumors result in osteolysis that is appreciable on standard foot radiographs. Other potential causes for local bone lysis would be infection, trauma and previous surgery. The differentials at this point included a)neoplasia, b)trauma and c)infection. Zoe’s age and breed make osteosarcoma one of the top cancers to consider. However, with her racing history, an Keratoacanthoma is a benign proliferation that arises from the superficial epithelium. When a keratoacanthoma forms beneath the nail, the tumor’s growth is directed instead at the space 12 VetWrap Volume 9 Issue 1 The experience you trust for emergencies, available for scheduled critical procedures too! Consultation & Referral Scheduling Available 24/7, 365 • P hone consultations • C onsultations • Same-day surgery referrals (Please speak to a surgeon or staff DVM prior to patient’s arrival.) main 503.228.7281 • backline 971.255.5990 • fax 503.228.0464 Figure 1 Figure 2 occupied by the third phalanx. Gradual expansion results in pressure necrosis and resorption of P3 such as that seen in Figure 1. Treatment for solitary tumors is excision and prognosis is excellent. In Zoe’s case, the toe involved was a weightbearing digit, thus amputation was expected to have a permanent effect upon her gait. At 3 months post-surgery, the owner reported that Zoe was sound in most of her activities, although occasionally she would stumble or take one or two lame steps. DoveLewis would like to thank the Pearl Animal Hospital and Zoe’s owner for allowing her case to be used for teaching purposes. Selected References: Canine digital tumors: a Veterinary Comparative Oncology Group retrospective study of 64 dogs. Henry CJ et al. JVIM 10:720-724, 2005. Radiographic changes associated with digital, metacarpal and metatarsal tumors and pododermatitis in the dog. Vet Radiol Ultrasound. 37:327-335, 1996. Volume 9 Issue 1 VetWrap 13 TECHNICIAN End Tidal C02: Worth the Investment? Megan Brashear, BS, CVT, VTS (ECC) If I were to take away all of your fancy anesthesia monitoring equipment and you could save ONE monitoring parameter, which would you choose to keep? Between heart rate/ ECG, ETC02, Sp02, blood pressure (noninvasive but you can choose Doppler unit or oscillometric), and temperature which would you choose? Thankfully many of us have the luxury of using all of these parameters plus our own eyeballs and fingers to monitor our anesthetized patients, but if I were down to just one, I do not want to monitor anesthesia without capnometry to measure end tidal C02. End tidal C02 is the measurement of carbon dioxide in each exhaled breath. Before getting into everything we can gain by monitoring this value, let’s think about why it is important to monitor. Carbon dioxide is the gas that drives respiration. We (and our patients) inhale because the respiratory center in our brain detects higher than normal levels of carbon dioxide in the blood. We inhale oxygen, and then exhale that carbon dioxide every minute of every day of our lives. If carbon dioxide levels get too high, our respiratory rate will increase so that we are exhaling more C02. If levels get too low, our respiratory rate decreases so that we hang on to more C02. In our normal patients without lung disease or metabolic disease, this process is sufficient to keep their C02 levels perfectly normal. When we anesthetize that patient, the drugs we use can decrease the ventilatory drive in the brain and relax the intercostal muscles which can cause changes in ETC02. Changes that, because they are anesthetized, the patient cannot correct on their own. Do we really need to monitor ETC02? We can see our patient breathing, we 14 VetWrap Volume 9 Issue 1 have the Sp02 giving us good numbers, why bother? First of all, our trusty pulse oximeter is only giving us part of the picture. With some fancy new models, we can get some impressive perfusion information from our pulse oximeter, but it is still only giving us oxygenation status of our patient. It is measuring the percentage of hemoglobin that is saturated with oxygen. This number tells us that the patient is receiving enough oxygen. When that patient is anesthetized and breathing 100% oxygen, a low patient Sp02 may be masked by the increase in inhaled oxygen. And the Sp02 monitor has its limitations – ambient light, probe placement, movement, and decreased peripheral perfusion can all alter the reading. By monitoring ETC02 we are able to determine our patient’s ventilation status. This is the physical movement of air in and out of the lungs and upper respiratory system. By using both ETC02 and Sp02 we are getting a more complete picture of our patient under anesthesia. Depending on who you read and where you work, the normal range for ETC02 may differ slightly, but I prefer to use 35mmHg-45mmHg as my ideal range for an anesthetized patient. Not only are we monitoring ventilation and respiratory drive with that normal range, we are also protecting the patient from acid/ base changes. Elevated levels of carbon dioxide can lead to acidosis which can bring additional problems to our anesthetized patient. By monitoring, we can intervene to keep the ETC02 within that normal range. An elevated ETC02 (>45mmHg), or hypercapnia, signifies that the patient is hypoventilating. Common causes for this include: too deep a plane of anesthesia, an airway obstruction, pneumothorax, body position of the patient, and disease process (remember that obesity is a disease, especially when we place those patients in dorsal recumbency). To correct hypercapnia, increase the patient’s respiratory rate until the ETC02 reaches a normal level, and adjust anesthesia as needed. Troubleshooting the patient may be necessary if a pneumothorax is present or the patient is not responding as anticipated. A decreased ETC02 (<35mmHG) or hypocapnia, signifies that the patient is hyperventilating. Common causes for this include: too light a plane of anesthesia, pain resulting in tachypnea, panting, pronounced hypothermia, decreased cardiac output, or excessive dead space in the anesthetic circuit. To correct hypocapnia, pain management or deeper anesthesia may be required to allow a lower respiratory rate, as well as monitoring other vital signs (such as temperature). Further troubleshooting may be necessary if the patient is not responding as anticipated. In addition to exhaled carbon dioxide, a capnometer will also display the inhaled C02 with each breath. This number is ideally zero, but it is acceptable for a patient to be rebreathing a small amount of C02, so a value of 1mmHg or 2mmHg is tolerable. Higher inhaled C02 numbers can indicate exhaustion of C02 granules or a malfunction with the anesthetic machine or circuit. In very small or debilitated patients, increased inhaled C02 numbers may signify a need for mechanical ventilation or switching to a non-rebreathing circuit. Many capnometers will also display each breath as a waveform, called a capnograph. Interpreting capnography is outside the scope of this article, but can give valuable information about breathing patterns, the presence of an airway obstruction, an airway leak, and breathing over a ventilator. As mentioned, an end tidal C02 monitor reads the amount of C02 exhaled with each breath. Whether a mainstream or side stream machine, you are looking at the result of not only ventilation, but also blood flow, cellular metabolism, and alveolar ventilation. In order for C02 to make it out of the lungs and into your capnometer, your patient must be perfusing cells and transporting C02 back to the lungs to be exhaled. ETC02 is reliant on ventilation and perfusion. It is also an instantaneous result, giving you up to the minute results of what is happening with your patient. We have discussed the respiratory monitoring, but ETC02 numbers are also a clue to the patient’s perfusion and circulation. Decreased cardiac output can lead to decreased ETC02. The patient continues to ventilate, exhaling C02, and if perfusion decreases there is less C02 being brought back to the lungs to be exhaled. A rapid drop in ETC02 is cause for alarm, as this can signify impending arrest. Watching ETC02 in relation to other vital signs under anesthesia will help you as the anesthetist gain a better overall understanding of your patient. For instance, you gather the following vitals on a 5 year old MN Doberman who is undergoing an elective procedure. He has been under anesthesia for 30 minutes when you record the following: • Heart rate – 52bpm (ECG normal) • Respiratory rate – 10bpm (on an anesthesia ventilator) • Mucous membranes – pink, CRT 1-2 seconds • SP02 – 99% • Temperature – 97.6°F • Blood pressure – 112/78 (MAP 84) • ETC02 – 33mmHg This is a young, healthy dog, and looking at his vitals you might be concerned about his bradycardia, but his blood pressure looks good, his gums are pink, he is doing fine, right? His ETC02 of 33mmHg is pretty close to normal - does his bradycardia really need to be addressed? Remember that ETC02 is also a measurement of metabolism and perfusion. The dog is hypothermic but not severe, the respiratory rate is not increased, but this patient may be hypoperfused due to his bradycardia. After treatment for his bradycardia with glycopyrrolate, this same patient then had the following vital signs: • Heart rate – 104bpm • Respiratory rate – 10bpm • Mucous membranes – pink, CRT 1-2 seconds • Sp02 – 99% • Temperature – 97.6°F • Blood pressure – 119/81 (MAP 89) • ETC02 – 41mmHg By increasing the heart rate we were able to see a slight increase in blood pressure, but the ETC02 came up to normal. As we improved perfusion, we improved ETC02. As mentioned previously, watch ETC02 for sudden changes, especially dropping. A level that is normal and suddenly decreases can signal impending arrest. As the animal stops perfusing, they exhale their C02 and blood flow is too poor to bring any new C02 to the lungs to be exhaled. That patient is in danger and needs help immediately. Using that same logic, monitoring ETC02 on a patient undergoing CPR can let you know when that patient has a return of spontaneous circulation. ETC02 readings in a patient that has arrested will be low, into the low teens or maybe even single digits, but as that animal begins perfusing their cells again the number will begin to slowly rise. Even if you are not convinced enough to say that ETC02 is your one and only monitoring parameter if you are forced to pick only one, hopefully you are convinced that monitoring ventilation and perfusion is a good idea, and worth the investment in an end tidal C02 monitor for your multi-parameter anesthesia monitor. A Big Heart USI works with many Northwest organizations and we understand the varied and complex issues you face in growing your business and protecting your assets. We specialize in providing: · · · · · Health & Wellness Benefits Retirement Plan Services Commercial Insurance Risk Management Private Client Wealth Management Elizabeth Templeton Vice President Employee Benefits 503.417.9231 Elizabeth.Templeton@usi.biz Volume 9 Issue 1 VetWrap 15 Connect with DoveLewis <<firstname>> <<lastname>>, <<title>> <<clinicname>> <<address>> <<city>>, <<state>> <<zip>> Volume 9 Issue 1 Winter 2015 Address changed? Want to switch to email? Contact James Gabrio jgabrio@dovelewis.org or 971.255.5937