Treatment injury case study March 2009 Sharing information to enhance patient safety EVENT: Failure to diagnose varicella pneumonia INJURY: Death Case study Tom, a 28-year-old, became unwell a few months after starting a new job as an early childhood teacher. Initially, Tom experienced a fever, which was soon followed by spots over much of his body and inside his mouth. As a number of children from his kindergarten were suffering from chickenpox, Tom went to see his GP. The GP noted that Tom had extensive vesicles and muscle aches, and was off his food but drinking well. She prescribed symptomatic treatment Key points • Adults with chickenpox may have, or may develop, pneumonia • Patients most at risk include pregnant women, smokers, those with impaired immune status, chronic lung disease, severe rash or persistent fever • Physical signs may be minimal – therefore an X-ray is essential if symptoms suggest pneumonia • Survival is improved by early antiviral treatment for high-risk groups, and hospitalisation of X-ray-proven cases. ACC216756_pr#6.indd 1 in the form of paracetamol and ibuprofen, but didn’t make any particular review arrangements. Two days later Tom began vomiting, was having trouble sleeping and still had no appetite. He returned to his GP and said he was feeling much worse. The GP found that Tom’s temperature was 38.1 degrees, but she took no further action other than to reassure Tom and send him home. The following evening Tom presented to the after-hours clinic with his partner. He told the after-hours doctor that he was exhausted, and his partner mentioned that she was very concerned about Tom’s condition. The doctor noted that Tom was distressed and took his temperature, which showed 37.9 degrees. There was no record of further examination, and once again Tom was reassured and sent home. Sadly, Tom died in his sleep that night. A Coroner’s post-mortem examination established the cause of death as varicella pneumonia. 09/03/2009 13:14:55 Case study Expert commentary Ian St George, General Practitioner, MD FRACP FRNZCGP DipEd GPs should be alert to the possibility of pneumonitis in any patient with chickenpox. Although difficult to diagnose, varicella pneumonia progresses to fatal respiratory failure in 5-10% of cases. This mortality can be considerably reduced with aggressive treatment (respiratory support and intravenous antiviral therapy) in hospital. The incidence of adult chickenpox has doubled in recent years, along with an increase in hospital admissions and mortality. Varicella pneumonia is the most common and serious complication of chickenpox in adults, with an incidence 25 times higher than in children. Pregnant women, previous or current smokers, and patients with impaired immune status or chronic lung disease all have an increased risk of developing pneumonia, as do those who have a severe rash or persistent fever. Varicella pneumonia usually presents one to six days after the onset of the rash, and can be associated with tachypnoea, chest tightness, cough, dyspnoea, fever and occasionally with pleuritic chest pain and haemoptysis – although chest symptoms may start before the skin rash. How ACC can help your patients following treatment injury Many patients may not require assistance following their treatment injury. However, for those who need help and have an accepted ACC claim for treatment injury, a range of help is available. This help will depend on the specific nature of the injury and the applicant’s personal circumstances, but may include things like: Physical findings are often minimal, but chest X-rays typically reveal nodular or interstitial pneumonitis. With the exception of hypoxia, physical signs are a poor indication of severity. The risk of developing respiratory failure requiring artificial ventilation is difficult to predict early in the disease. In one report, X-ray abnormalities were detected in nearly 16% of enlisted military personnel who developed varicella, yet only one-quarter of these had a cough and only 10% of those with X-ray abnormalities developed tachypnoea. Acyclovir has become standard therapy for patients with, or at risk of developing, complications of varicella infection. Currently, the consensus is to use acyclovir daily for 7-10 days, but this use should be tailored to each patient’s clinical assessment. References 1. Wilkins EGL, Leen CLS, McKendrick MW, Carrington D. Management of chickenpox in the adult – a review prepared for the UK Advisory Group on Chickenpox on behalf of the British Society for the Study of Infection. J Infect 1998; 36 (Suppl 1): 49-58. 2. Mohsen AH, McKendrick M. Varicella pneumonia in adults. Eur Respir J 2003 May;21(5):886-91. (http://erj.ersjournals.com/cgi/content/ full/21/5/886) 3. Shepherd J, Harris T, Harrison T and Hilton S. General practice survey of the management of chickenpox: appropriate targeting of antiviral therapy. Family Practice 2001; 18: 249–252. Claims information Between July 2005 and January 2009, ACC received 28 treatment injury claims relating to a delay or failure in diagnosing or treating infections. Of these, 16 claims (57.1%) were accepted. Various types of infection were represented in the accepted claims, including septicaemia, wound infection and septic arthritis. Two accepted claims related to pneumonia. The most common reasons for declining claims were that the treatment (including diagnosis) was reasonable in the circumstances, or that the perceived failure to diagnose or treat, did not cause an injury. • a contribution towards treatment costs • weekly compensation for lost income (if there’s an inability to work because of the injury) • help at home, with things like housekeeping and childcare • a contribution to the cost of travel to and from treatment About this case study • changes to the home, such as the installation of rails and wheelchair ramps • personal aids, such as crutches and wheelchairs. This case study is based on information amalgamated from a number of claims. The name given to the patient is therefore not a real one. No help can be given until a claim is accepted, but it’s a good idea to keep receipts for any injury-related costs, as ACC may be able to reimburse these. It’s important to make a claim for a treatment injury as soon as possible after the injury. This will ensure ACC is able to investigate, make a decision and, if covered, help your patient with their recovery. The case study has been produced by ACC’s Treatment Injury Centre, to provide health professionals with: • • an overview of the factors leading to treatment injury expert commentary on how similar injuries might be avoided in the future. Send your feedback: AdminTeamTI&PS@acc.co.nz ACC5080 Printed March 2009 ©ACC 2009 ACC216756_pr#6.indd 2 09/03/2009 13:14:56