CGH 302: Epidemiology Fall 2013 Schedule: Tuesdays and Thursdays, 9:00 AM – 11:50 AM ACB 214 *Nov 14: class will be in Burkle14 Office Hours: By appointment Instructor: Kari-Lyn K. Sakuma, Ph.D., MPH Assistant Professor School of Community & Global Health karilyn.sakuma@cgu.edu TA: Mark Dust School of Community & Global Health mark.dust@cgu.edu Textbook: Friis, R.H. & Sellers, T.A. Epidemiology for Public Health Practice: Fifth Edition. Boston: Jones and Bartlett. Available at the bookstore or through Amazon and other online retailers. Online Course Management Announcements and digital handouts will be provided through Sakai. Slides will be provided and posted to Sakai AFTER each class session. If you have trouble accessing Sakai, please contact Maggie Hawkins (Margaret.hawkins@cgu.edu) for assistance. Course description: This course is an introduction to the methods and applications of epidemiology, with an emphasis on applications to community and global health issues. The field of epidemiology is concerned with the distribution and determinants of health and diseases, morbidity, injuries, disability, and mortality in populations. Epidemiologic studies are applied to the control of health problems in populations; therefore, a thorough understanding of epidemiology is essential for research and practice in community and global health. In this course, students will learn the core concepts of epidemiology including measures of morbidity and mortality, sources of data, study designs, measures of effect, screening measures, and practical applications. Students will apply this knowledge to a current community/global health problem of their choice. Learning objectives: After taking this course, students should be able to: Describe the role that epidemiology serves in the discipline of public health, and be able to describe a public health problem in terms of magnitude, people, time, and place. Apply proper terminology and definitions used in epidemiology. Identify key sources of data for epidemiologic studies. Identify various study designs used in epidemiology and describe their strengths and limitations. Calculate the basic statistics used in epidemiology, including morbidity and mortality rates, incidence and prevalence, sensitivity and specificity of screening tests, and measures of effect. Explain the importance of epidemiology for informing scientific, ethical, economic and political discussion of health issues. Comprehend ethical principles pertaining to the collection, maintenance, use and dissemination of data and other epidemiological information. Interpret, articulate, and critique results of epidemiological analyses found in public health studies. Develop written and oral presentation based on epidemiological studies for both public health professionals 1 and educated lay audiences. Course components: Requirement Percent of grade Mid-term exam 20% Final Exam 20% Epi in the news assignment 15% Group Study Critique 20% Group In-Class Activity 20% Class Participation 5% Total 100% Grading system Letter grades are assigned by these standards: Letter Grade A+ A AB+ B BC+ C C- Percent Scale Interpretation 97-100 93-96.9 90-92.9 87-89.9 83-86.9 80-82.9 77-79.9 73-76.9 70-72.9 4.0 4.0 3.7 3.3 3.0 2.7 2.3 2.0 1.7 Truly exceptional performance; rarely given Excellent performance. Very Good performance. Good performance. Acceptable performance. Marginally acceptable performance. Passing but below expectations for graduate work. NO EXTRA CREDIT! You can earn a good grade without extra credit if you do quality work throughout the term. Grades are EARNED not given. Class Structure: Generally, the first 2hrs of class will be devoted to lectures and in-class assignments. The last 50 minutes will generally be spent reviewing concepts covered in class and/or working on your group projects or assignments. Evaluative Criteria: Mid-term exam (20%) and Final Exam (20%): All exams will be primarily multiple choice questions but will also include short-answer questions. Exams will cover all material in the textbook and lectures. Each exam will cover material presented since the previous exam. The final exam may be cumulative due to the nature of the advanced lectures. o Both exams will be CLOSED BOOK but you can have a single, 8½ X 11 sheet of paper (front & back) for notes. o Except for calculators, NO laptops or other electronic devices will be allowed during the quizzes. You cannot use your phone or computer as your calculator. Epi in the News Assignment (15%) Due by 9am on 11/26/2013 Assignments received after 9am will be marked down 5%. For every day an assignment is late, an 2 additional 5% will be deducted from the grade. Directions: Find an example of a news story about an epidemiological study. o Sources may include newspaper, magazine (not scientific journals) or internet (from professional news agencies). Write no more than two pages (typed, font size 12, single spaced) describing the following aspects of the study: 1) What was the research question under study? (Identify exposure and outcome explicitly.) 2) What was the source of the data used in the study? (Identify person, place and time elements.) 3) What study design was used? 4) What were the key results and conclusions? (Be concise but thorough.) 5) Choose two ‘criteria for causation’ that are relevant to the epidemiologic study and describe the extent to which each is (or is not) met. If adequate information is not presented in the article to answer any of the above questions, please do your best to provide an answer and state what information would be required to more fully answer the question. Please attach a hardcopy of your chosen news article to your typed assignment. Study Critique (20%) Due by 9am on 12/17/2013 Assignments received after 9am will be marked down 5%. For every day an assignment is late, an additional 5% will be deducted from the grade. This is a group assignment. Groups will be determined the first week of class start. Since this is a group project, everyone in the group will receive the same grade. o For example, if someone plagiarizes a section of the critique then everyone gets the failing grade. Project Description o Describe a current community/global health issue. This can be a disease (e.g., cancer), a behavior (e.g., sedentary behavior), or an environmental condition (e.g., exposure to a toxic chemical). o Describe the extent of the problem using epidemiologic measures (e.g., incidence, prevalence). o Choose TWO epidemiologic studies to critique. Answer the following questions in a written essay format. 1. Identify the primary research question being addressed by the investigation. 2. Identify the primary independent (exposure) and dependent (disease outcome) variables being examined (i.e. if “this,” then “that”). 3. Describe the subjects involved in the investigation. 4. Explain how the exposure and outcome variables were defined and measured. 5. Identify the basic type of study design utilized. 6. Identify the key results, i.e. the reported association between the exposure and the outcome. 7. Recognize potentially confounding variables, potential sources of differential misclassification (i.e. selection bias and measurement bias), and potential sources of non-differential misclassification. Also recognize efforts to deal with each of these; and evaluate the adequacy of these efforts. 8. Recognize situations in which confounding, measurement bias, and/or selection bias are NOT likely explanations for the findings and explain why. 9. Determine whether the interpretation of the results and conclusions of the author(s) are justified by the findings. 10. Summarize the major strengths and weaknesses of the study. Please use a professional, scientific writing style, and make sure the writing is your own. Be concise. Longer is not better. Critiques should not be longer than 10 pages (12 point font, single-spaced, don’t forget to use appropriate citations). You are expected to present your critique to the class on 12/17/2013. Most students find it helpful to use PowerPoint presentations with bullet points, tables, and/or graphs to organize their presentations. 3 Presentations should be around 20 minutes with 5 minutes for questions. Please turn in a paper copy of the two articles your group chose to critique, the written critique, and a copy of the slides presented to the class. In-Class Activity (20%) Teaching is the best way to learn something inside and out. You will be assigned to a group at the beginning of the semester and will be expected to teach, demonstrate, and answer questions surrounding the lecture topic to the rest of the class. Creativity is key! This class activity should last no more than 20 minutes. Schedule of classes Date Instructor Topic 10/29 Sakuma Introduction History and scope of epidemiology Practical applications of epidemiology -Group presentation example 10/31 Sabado Measures of morbidity and mortality used in epidemiology 11/5 Sakuma Descriptive epidemiology: Person, place, time -Group A presentation (Ch. 3) 11/7 Sakuma Sources of data for use in epidemiology -Group B presentation (Ch. 4) 11/12 Sakuma Study designs: Ecologic, cross-sectional, case-control 11/14 Dust Study designs: *Burkle Cohort, experimental 14 -Group C presentation (Ch. 6) 11/19 Sakuma Measures of effect Data interpretation issues -Group D presentation (Ch. 7) -Group E presentation (Ch. 8) 11/21 Mid-Term Exam 11/26 Epi in the News DUE at 9am Sakuma Mid-term Exam Review Answers Study Critique Exercise and Example THANKSGIVING BREAK 12/3 Sakuma Screening for disease in the community Epidemiology of infectious diseases 12/5 Sabado Psychologic, behavioral, social, genetic epidemiology -Group F presentation (Ch. 11) -Group G presentation (Ch.12) 12/10 Sakuma Ogata Environmental and Occupational Epidemiology; Epidemiology as a profession 12/12 12/17 Sakuma Class Recap- Review for Final Critique Papers are Due by 9am Group Critique Presentations Final Exam 12/19 Reading Chapters 1,2 Chapter 3 Chapter 4 Chapter 5 Chapter 6 Chapters 7, 8 Chapters 9, 10 Chapters 11, 12 Chapters 14 (skim), 15 Chapters 13, 16 Course Policies: Any student requesting academic accommodations based on a disability is required to register with the office of Disability Services. A letter of verification for approved accommodations can be obtained from Disability Services. Please be certain the letter is delivered to me as early in the semester as possible. The Disability 4 Services office is located in Harper Hall, Lower Level, Room 14. The phone number is (909) 607-8779 or you may email them at disabilityservices@cgu.edu. The website is: http://www.cgu.edu/pages/1154.asp. Academic Integrity: Students of Claremont are expected to do their own work and respect the intellectual properties of others. You are held to the University’s Code of Academic Integrity. All students are responsible for reading and following the Student Conduct Code, which can be found at http://www.cgu.edu/pages/1132.asp. Violation of academic integrity can result in serious consequences such as, but not limited to receiving an “F” on the assignment and/or in the final grade of the course, or being expelled from the University. There is a “zero tolerance” policy in this class. Academic misconduct will be reported to the University for Independent Review. Misconduct can include using unapproved notes or talking during exams, using materials in your papers without proper citation, and plagiarizing others’ work or using your own work from other classes and turning it in for credit in this class. Unexcused late work. There will be no make-up in-class assignments or presentations offered or accepted. There will be no extra credit offered. FINAL EXAMS CANNOT BE MISSED. THE FINAL EXAM IS ON DEC 19 from 9am to 11:50am. Acceptable excuses such as medical emergencies must be accompanied by a note by a physician or health clinic. E-mail Courtesy: Please do not email at 10pm the night before an exam expecting an immediate answer. Please give us at least 24 hours during the work week to respond to emails. We may get to it prior to then but do not rely on instant contact 24/7. I know this may be difficult but like you, we have many other responsibilities that need our attention and extending this courtesy to us will be greatly appreciated. E-mailed papers and papers delivered to mailboxes or left in the offices of the professor or teaching assistant will not be considered “received” or “turned in” until the professor or teaching assistant get it, open the document, and acknowledge receipt of it. If you send any files or attachments, please include the course number, content or file, and your name in the electronic file name as follows: CGH302_<type of doc>_<lastname>.doc (i.e., CGH302_finalpaper_Sakuma.doc). Grammar, spelling and writing ability are important. Please edit all written assignments and turn-in written materials that are error-free and meet the quality standards of the university. OPEN DOOR: I strongly encourage you to speak with me and/or the teaching assistant if you have any questions or concerns about any particular assignment, concept, or perhaps about the class in general. If you are having a difficult time in this class or meeting the demands of the coursework, please communicate with me or the teaching assistant. You may email us and make an appointment or you can simply catch one of us before or after class. Our doors are open. 5