Dr. Huang, Yi-Hsiang Contact Information Phone Email +886-2-28757826 Ext. 2972 yhhuang@vghtpe.gov.tw Educations 2004 Ph.D., National Yang-Ming University 1991 M.D., National Yang-Ming University Experiences 2011 2007 2007 2006 Professor, Institute of Clinical Medicine, Natl. Yang-Ming Univ., Taipei, Taiwan Associate Professor, Institute of Clinical Medicine, Natl. Yang-Ming Univ., Taipei, Taiwan Associate Professor, Faculty of Medicine, Natl. Yang-Ming Univ., Taipei, Taiwan Postdoctoral fellow, National Cancer Institute, NIH Research Interests 1. Viral immunology 2. Tumor Immunology 3. Hepatology Honors and Awards 2010 Best Research Paper Award, Taipei Veterans General Hospital 2006 Taiwan Merit Scholarship, National Science Council, ROC 2004 Physician Research Scholarships, Institute of Biomedical Science, Academic Sinica Physician Research Scholarships, Institute of Biomedical Science, Academic Sinica 2003 2001 Academic Award of Prof. JL Sung’s Research Foundation 2001 Physician Research Scholarships, Institute of Biomedical Science, Academic Sinica 2000 Physician Research Scholarships, Institute of Biomedical Science, Academic Sinica Selected publications Title Survival impact of delayed treatment in patients with Journal Year IF(2010) SCANDINAVIAN hepatocellular carcinoma undergoing locoregional therapy: Is JOURNAL OF 2007 1.758 2007 5.332 2007 2.384 2007 6.642 LIVER INTERNATIONAL 2008 2.908 there a lead-time bias? GASTROENTEROLOGY Positive selection of hepatitis delta antigen in chronic JOURNAL OF hepatitis D patients VIROLOGY The predictive ability of serum alpha-fetoprotein for JOURNAL OF SURGICAL hepatocellular carcinoma is linked with the characteristics of ONCOLOGY the target population at surveillance Genetic polymorphisms of manganese superoxide dismutase, JOURNAL OF NAD(P)H : quinone oxidoreductase, glutathione S-transferase HEPATOLOGY M1 and T1, and the susceptibility to drug-induced liver injury Natural history and prognostic factors of primary biliary cirrhosis in Taiwan: a follow-up study up to 18 years Validation of the HCC-MELD for dropout probability in CLINICAL patients with small hepatocellular carcinoma undergoing 2008 1.915 2008 5.308 TRANSPLANTATION locoregional therapy Hepatitis B surface antigen levels and sequences of natural JOURNAL OF hepatitis B virus variants influence the assembly and VIROLOGY secretion of hepatitis D virus Successful radiofrequency ablation therapy for hepatocellular JOURNAL OF THE carcinoma in a male patient with early stage primary biliary CHINESE MEDICAL cirrhosis and positive serum hepatitis B core antibody ASSOCIATION 2008 JOURNAL OF THE Cholestatic jaundice as the predominant presentation in a CHINESE MEDICAL 2008 patient with autoimmune hepatitis ASSOCIATION Characteristics and outcome of patients with dual hepatitis B and C-associated hepatocellular carcinoma: are they different LIVER INTERNATIONAL 2009 2.987 from patients with single virus infection? Fatal Reactivation of Hepatitis B Virus in a Patient Who Was Hepatitis B Surface Antigen Negative and Core Antibody JOURNAL OF CLINICAL Positive Before Receiving Chemotherapy for Non-Hodgkin GASTROENTEROLOGY 2009 Lymphoma 2.207 Selecting a Short-term Prognostic Model for Hepatocellular Carcinoma Comparison Between the Model for End-stage JOURNAL OF CLINICAL Liver Disease (MELD), MELD-sodium, and Five Cancer GASTROENTEROLOGY 2009 2.207 2009 2.207 2009 7.818 2009 2.207 2009 7.818 Staging Systems Fatal Reactivation of Hepatitis B Virus in a Patient Who Was Hepatitis B Surface Antigen Negative and Core Antibody JOURNAL OF CLINICAL Positive Before Receiving Chemotherapy for Non-Hodgkin GASTROENTEROLOGY Lymphoma Generation of cytotoxicity against hepatitis delta virus JOURNAL OF genotypes and quasispecies by epitope modification HEPATOLOGY Selecting a Short-term Prognostic Model for Hepatocellular Carcinoma Comparison Between the Model for End-stage JOURNAL OF CLINICAL Liver Disease (MELD), MELD-sodium, and Five Cancer GASTROENTEROLOGY Staging Systems Risk factors for early and late recurrence in hepatitis JOURNAL OF B-related hepatocellular carcinoma HEPATOLOGY JOURNAL OF THE 2009 Novel H1N1 Influenza: The Impact of Viral Genomic CHINESE MEDICAL 2009 Reassortment on Immune Evasion and Vaccine Strategy ASSOCIATION Renal failure in patients with hepatocellular carcinoma and LIVER INTERNATIONAL 2010 3.840 ascites undergoing transarterial chemoembolization Hepatitis B Virus Reactivation After 23 Months of JOURNAL OF THE Rituximab-based Chemotherapy in an HBsAg-negative, CHINESE MEDICAL Anti-HBs-positive Patient With Follicular Lymphoma ASSOCIATION Core Antigen Expression Is Associated with Hepatic CLINICAL AND 2010 0.678 2010 2.471 histology in HBeAg-negative chronic hepatitis B: a novel role LIVER INTERNATIONAL 2010 3.840 Necroinflammation in e Antigen-Negative Chronic Hepatitis VACCINE B Patients with Low DNA Loads IMMUNOLOGY Correlation between clinical indication for treatment and liver of alpha-fetoprotein Fibrosis and AST to platelet ratio index predict post-operative HEPATOLOGY prognosis for solitary small hepatitis B-related hepatocellular 2010 2.963 LIVER INTERNATIONAL 2010 3.840 INTERNATIONAL carcinoma Diabetes mellitus as an independent prognostic predictor and its association with renal dysfunction in patients with hepatocellular carcinoma Transarterial Chemoembolization in Patients With JOURNAL OF CLINICAL Hepatocellular Carcinoma and Renal Insufficiency GASTROENTEROLOGY 2010 2.752 A new prognostic model for hepatocellular carcinoma based JOURNAL OF 2010 9.334 2010 5.131 Survival Rates Are Comparable After Radiofrequency CLINICAL Ablation or Surgery in Patients With Small Hepatocellular GASTROENTEROLOGY 2011 5.286 Carcinomas AND HEPATOLOGY on total tumor volume: The Taipei Integrated Scoring system HEPATOLOGY Selecting an Optimal Staging System for Hepatocellular CANCER Carcinoma Comparison of Radiofrequency Ablation and Transarterial LIVER Chemoembolization for Hepatocellular Carcinoma Within the 2011 3.068 2011 2.963 2011 4.713 2011 1.598 2011 2.752 2011 3.410 2012 2.752 TRANSPLANTATION Milan Criteria: A Propensity Score Analysis Early identification of poor responders to transarterial HEPATOLOGY chemoembolization for hepatocellular carcinoma INTERNATIONAL The protective role of natural phytoalexin resveratrol on MOLECULAR inflammation, fibrosis and regeneration in cholestatic liver NUTRITION & FOOD injury RESEARCH EUROPEAN JOURNAL Risk factors for long-term prognosis in hepatocellular OF carcinoma after radiofrequency ablation therapy: the clinical GASTROENTEROLOGY implication of aspartate aminotransferase-platelet ratio index & HEPATOLOGY Liver Failure After Transarterial Chemoembolization for JOURNAL OF CLINICAL Patients With Hepatocellular Carcinoma and Ascites GASTROENTEROLOGY Incidence, Risk Factors, and Prognostic Prediction Impact of body mass index and viral load on liver histology in CLINICAL NUTRITION hepatitis B e antigen-negative chronic hepatitis B Younger Hepatocellular Carcinoma Patients Have Better JOURNAL OF CLINICAL Prognosis After Percutaneous Radiofrequency Ablation GASTROENTEROLOGY Therapy Lab Members Lab Photos