PROTEIN SCIENCE LINE A – PENSUM 2007
Whitford, D: “Proteins. Structure and Function” 1st Ed. (2005), Wiley & Sons.
Chap. 2, p. 13-32.
Chap. 3, p. 39-50.
Chap. 5, p. 105-119, 128-132
Chap. 7, p. 195-197, 202-215, 218-221, 237-241
Chap. 9, p. 313-345
Chap. 10, p. 346-360
Chap. 11 p. 379-383, 385-387, 395-415, 426-437
Fersht, AR: “Structure and mechanism in protein science”, Freeman
Chap. 1D, p. 25-34 (minus D6) PS9
Chap. 5, 5A, p. 169-173, 5D, pages 179-181, 5H- 5I, pages 187-189 PS10
Chap. 15E-F, p. 427-430 PS10
Chap. 17D, p. 523-532
Chap. 18, p. 558-563
K. E. van Holde, W. Curtis Johnson, P. Sing Ho ”Physical Biochemistry”
Chap. 3, p. 90-116, 128-136
Chap. 15, p. 593-621 PS8
Wilkinson, K.D: in “Protein-protein interactions. Methods and applications”.
Chap 2, p. 15-31 PS8
Creighton: “Protein” Freeman
Chap. 9.2.6, p. 410-413 PS10
Method Book for Protein Science
Lab-manual Protein Science Basic
Lab-manual Protein Science Advanced – A-line
Lecture Notes
Lecture notes to PS 1 A+C: Slides marked curriculum
Lecture notes for PS9A-F: Slides marked curriculum PS9
Lecture notes to PS10AC: Slides marked curriculum PS10
Notes for NMR Spectroscopy of Proteins; PS4
Notes 2 for NMR spectroscopy of Proteins PS4
Notes on ligand binding. PS8
Scientific papers
1) Qin et al. (2000) Copper(II)-induced Conformational Changes and Protease
Resistance in
Recombinant and Cellular PrP. Effect of Protein Age and Deamidation. J. Biol. Chem.
275, 1912119131 (minus fig. 3)
2) Mercado-Flores Y, Trejo-Aguilar A, Ramirez-Zavala B, Villa-Tanaca L, HernandezRodriguez C.
Purification and characterization of an intracellular aspartyl acid proteinase (pumAi)
from Ustilago
maydis. Can J Microbiol. 2005;51:171-5
3) Deechongkit et al., (2004). Context-dependent contribution of backbone hydrogen
bonding to
β-sheet folding energies. Nature, 430, 101-105.
4) McPherson, A. (2004) Introduction to protein crystallization. Methods 34, 254-265
5) Müller, A., ….., Kelly, D.J. (2007) A Bacterial Virulence factor… J. Mol. Biol. 372,
160-171
6) Heijne, G.v. (1007) The membrane protein universe: what’s out there and why
bother? J. Int.
Med. 261, 543-557
7) Mullan, LJ, (2003) Hydrophathy – a window on the evasion of water. Briefings in
Bioinf. 4,
279-282
8) Clarkson & Wells. (1995) “A hot spot of binding energy in a hormone receptor
interface.
Science, 267, 383-386;
9) Tyers and Mann (2003) From genomics to proteomics. Nature 422, 193-196
(minus Openaccess
proteomics).
10) Lasonder et al. (2002) Analysis of the Plasmodium falciparum proteome by highaccuracy
mass spectrometry. Nature 419, 537-542.
11) Xu et al. (2001) Covalent inhibition revealed by the crystal structure of the
caspase-8/p35
complex. Nature 410, 494-497
12) F. Chiti, C. M. Dobson, Annu.Rev.Biochem. 75, 333-366 (2006)