CALL FOR EUROPEAN RESEARCH CENTERS INTERESTED IN RECEIVING A FELLOW FROM ANOTHER EUROPEAN COUNTRY Name of the Institution: _IIS-FUNDACION JIMENEZ DIAZ____ Web site of the Institution: http://www.fjd.es/instituto_investigacion/inicio.html Contact person: __ALBERTO ORTIZ________________________ Address:_______DIALYSIS, FUNDACION JIMENEZ DIAZ AV REYES CATOLICOS 2 Postal code: _28040____ City: ___MADRID__________ Country: ___SPAIN__________________________ Phone: ___915504800 EXT 3518______ Fax: E-mail: AORTIZ@FJD.ES ALBERTORETINA@HOTMAIL.ES Synopsis on research programme in Nephrology/ Dialysis/ Transplantation (the synopsis must not exceed 3500 character –font 12, word format only-). The renal unit at Fundacion Jimenez Diaz (Chief and Full Professor Jesus Egido) was designed to accommodate Clinical care, research and teaching activities. From a clinical point of view there are clinical nephrology, hemodialysis, peritoneal dialysis and transplantation programs. From a research point of view, more than 30 basic researchers collaborate with clinical staff and researcher in a lab with up-to-date research facilities. This results a constant stream of high level publications, including the top journals in nephrology such as JASN, Kidney Int and NDT. The h index for the two main principal investigators in the unit is 56 and 29, respectively. The Fundacion Jimenez Diaz renal unit is integrated in several European Union projects, ERA-EDTA working groups (it has representatives in both the Immunonephrology and EURECA-m working groups core members) and is integrated in other European initiatives such as the EUROKUP COST action and in the Spanish renal research network (REDINREN). The research centre of the Fundacion Jimenez Diaz, the IIS-Fundacion Jimenez Diaz is a joint venture with the Universidad Autonoma de Madrid. For over 30 years clinical and research fellows from Spain, other European countries (Rumania, Bulgaria), South America (Peru, Ecuador, Argentina, Chile, Uruguay, Paraguay) and Asia (China, Japan) have been trained at our Unit. Current lines of research. A) clinical research: EURECA-m Registry and biobanking of a dialysis cohort: involves characterizing vascular and bone disease, managing samples, echography, data analysis and paper writing B) Clinically oriented research of either if the following topics: * diabetic nephropathy: in search of novel therapeutic targets and biomarkers. It involves clinical phenotyping, clinical sample management, cell and animal models of diabetes, cell and molecular biology * pathogenesis of proteinuria: in search of novel therapeutic targets and biomarkers. It involves clinical sample management, cell and animal models of podocyte injury, cell and molecular biology * Molecular mechanisms of kidney injury in Fabry disease: in search of novel therapeutic targets and biomarkers. It involves cell and (probably soon) animal models of Fabry disease, cell and molecular biology * Novel mediators of kidney fibrosis and inflammation: It involves cell and animal models of kidney fibrosis and inflammation, cell and molecular biology * Pathogenesis and early diagnosis of acute kidney injury (AKI): in search of novel therapeutic targets and biomarkers. It involves clinical phenotyping, clinical sample management, cell and animal models of AKI and nephrotoxicity, cell and molecular biology + urine and tissue proteomics Research/es in which the Fellow will be involved. The fellow may choose from the following possibilities A) clinical research: EURECA-m Registry and biobanking of a dialysis cohort: involves characterizing vascular and bone disease, managing samples, echography, data analysis and paper writing B) Clinically oriented research of either if the following topics: * diabetic nephropathy: in search of novel therapeutic targets and biomarkers. It involves clinical phenotyping, clinical sample management, cell and animal models of diabetes, cell and molecular biology * pathogenesis of proteinuria: in search of novel therapeutic targets and biomarkers. It involves clinical sample management, cell and animal models of podocyte injury, cell and molecular biology * Molecular mechanisms of kidney injury in Fabry disease: in search of novel therapeutic targets and biomarkers. It involves cell and (probably soon) animal models of Fabry disease, cell and molecular biology * Novel mediators of kidney fibrosis and inflammation: It involves cell and animal models of kidney fibrosis and inflammation, cell and molecular biology * Pathogenesis and early diagnosis of acute kidney injury (AKI): in search of novel therapeutic targets and biomarkers. It involves clinical phenotyping, clinical sample management, cell and animal models of AKI and nephrotoxicity, cell and molecular biology Please, return this form, as an attachment, to the following e-mail address: fellowships@era-edta.org