Dr. Subramanian’s Research Resume Resume Personnel Details: Name : Date of Birth : Gender: Marital Status : Address (Present): Dr Subramanian S 21 August 1970 Male Married #39/4(13/4), SSL Brindavan Permanent: IV Cross Street, Andal Nagar Adambakkam, Chennai, 6000 88. E-mail: sambandam.subramanian@gmail.com subramanian@scientist.com Mobile: +91-8760624786 & 9444572720 219A, Soriyan Street Veeriyankottai Villege Peravurani Taluk Thanjavur-614804. Key Skills: Research experience with Stem Cell Regenerative Medicine - CD34+ stem cells expansion and transformation using various factors to establish inner hair cells for the cure of deafness in rodent model study. Experience in handling small rodents like rats and mice Research experience with Autoimmune Disease like Arthritis, Alzheimer’s Research experience with Lipid Biochemistry, Drug Discovery and Pre-Clinical Research experience with Piezoelectricity Research on Deafness & P.G. level teaching with Life Science subjects Training in Stem Cell Regenerative Medicine Research: Training Programme on Regenerative Medicine (TPRM) for clinical stem cell research from University of Toronto, Canada at Nichi-In Centre for Regenerative Medicine, NCRM-Japan (Chennai Centre). Research Projects Handled: Stem Cell Regenerative Medicine application for the cure for deafness. This research project involves isolation of inner hair cells from rats and subsequently isolation, purification and expansion of hematopoietic stem cells from rodents and further transformation using transforming factors like neuro-growth factors (Glial cell-line Derived Neurotrophic Factor). This was further under application for everlasting implantation for inner hair cells transformation for the cure of deafness. Study on the piezoelectric property of the middle ear bones. This research project involves isolation of middle ear bones viz., malleus, incus and stapes. Using various laboratory techniques like transmission electron microscopy, scanning electron microscopy, X-ray diffraction techniques, Mass Spectrometry and Raman spectra studies, the piezoelectric behavior on how the transforming wave to become converted to understand sound or voice. The laboratory facility is provided by Indira Gandhi Centre for Atomic Research (IGCAR), Kalpakkam. This project proposal was submitted to Science and Engineering Research Council, DST-India. Drug Discovery - Neuro-Degenerative Disease-Rodent model study at Central Leather Research Institute, Council of Scientific & Industrial Research, Chennai. This ICMR project involves, synthesis of alpha crystalline (alphaB-crystallin) as small heat shock proteins (sHSP) from E. coli bacteria and tested against neuro-inflammation induced in rats for novel drug discovery on Alzheimer's disease. Lipid Research- Rodent model study, Department of Zoology, Government Arts College, University of Madras, Chennai, India. This project is funded by UGC, India. The research project involves studies on the prevention of bad cholesterol by taking gingili oil in food. The gingili oil goodness with cholesterol metabolism was studied using small rodent viz., rats. Dr. Subramanian’s Research Resume Work experience: Research Scientist (From Feb. 2008 to Dec. 2010), International Research Institute For The Deaf (IRID), India, Chennai, India. Research Associate – From Sep.2004 to Dec.2007, Drug Discovery - Rodent model study, Central Leather Research Institute, Council of Scientific & Industrial Research, Chennai, India. Research Associate- (From Feb.2001 to July 2004), Lipid Research - Rodent model study, Department of Zoology, Government Arts College, University of Madras, Chennai, India. Education: Ph.D., University of Madras, Chennai, India/2002. Title of the Ph.D. thesis: Tissue metabolic, biochemical, histopathological, hematological and immunological parameters in the CFA induced arthritic rats (Wistar rats - Rattus norvegicus) - A Laboratory Animal Model Investigation. M.Sc., Zoology, Annamalai University, India/1995 & B.Sc., Zoology, Madras of University, India/1992. Computer Education: Diploma in Computer Application, Loyola Institute of Business Administration and Informatics Centre, Loyola College, Affiliated to the University of Madras, India & Oracle (7.0) - Sabari Computer Education, Chennai, India. Regional Editor Asian Journal of Medical Sciences, Journal of Infectious Diseases and Immunity, Current Research Journal of Biological Sciences, Journal of Bacteriology Research Membership Life Member, Indian Science Congress Association (ISCA) Executive Member Human Right Guild, Tamilnadu, India. Reference Dr. K. Ramalingam, Ph.D. Supervisor/Guide Retd. Prof. of Zoology Govt. Arts College Nandanam, Chennai. Mobile. 9710039843 Dr. Subramanian’s Research Resume PPublications Year 1 2011 2 2011 3 2010 4 2010 5 2009 6 2009 7 2009 8 2009 9 2009 10 2006 11 2005 12 2005 13 2004 14 2004 15 2003 16 2003 17 2003 18 2003 19 2002 20 2002 21 2000 22 2000 23 2000 Title Journal Does stem cell regenerative medicine could provide good Under Preparation clinical outcome for deafness? – The focus on current difficulties on clinical application A hypothetical note on electrical field created by piezoelectric Under Preparation middle ear bone on inner hair cell regeneration. Fibroblast growth factor-2 (Fgf-2) Role on Inner Hair Cell Current Research Journal of Biological Regeneration and Tumor Growth with regards to Sciences. Vol. 2(2): 51-55. Regenerative Medicine – A Review. http://www.maxwellsci.com Immunological and Biochemical Factors in liver Amyloidosis Journal of Experimental Biological of Adjuvant arthritic rats Rattus norvegicus Sciences. Vol. 1(1): 101- 105. www.ajebs.com Musculo-skeletal joint inflammatory diseases - New vistas Journal of Biochemical Technology. from animal model studies – An overview 1(4):108-113. http://jbiochemtech.com Etiopathogenesis of RA have misunderstood of non- Journal of Medical Sciences. infectious 1(2): 1-9. http://www.maxwellsci.com Immune mediated and drug toxicity caused structural Current Research Journal of Biological changes in different regions of adjuvant-induced arthritis – A Sciences. histopathological study. 1(2): 27-33. http://www.maxwellsci.com Diclofenac induced toxic manifestations on adjuvant induced Journal of Toxicology and arthritic rats pheripheral and reproductive organ of male Environmental Health Sciences. Wistar rats Rattus norvegicus 1 (1) pp. 012-021. http://www.academicjournals.org/JTEHS Does intrinsic defect in immune system to common microbial Biology and Medicine. antigen play important role in the manifestation of rheumatoid 1 (3): Rev1. http://www.biolmedonline.com. arthritis? Role of brain metabolites as substantial factors and enzymes Journal of Nature Conservators. 18(2)in immune complex formation in CFA induced inflammation 333-339. (arthritis) in Wistar rats Rattus norvegicus Adjuvant induced alterations in metabolites and enzyme Journal of Nature Conservator. system in the muscle region of Rattus norvegicus 17(2):273-282. Electron microscopic evidence on the participation of Asian Journal of Microbiology, Cytotoxic T-lymphocyte and macrophages in MTB- adjuvant Biotechnology & Environmental induced connective tissue inflammation and arthritogenesis Sciences. in Rattus norvegicus 7(2) 227-233. Cell mediated and humoral immune response in CFA Journal of Ecotoxicol & Environmental induced arthritis in Rattus norvegicus Monitoring. 14(14):291-298. Distribution of monoamines in the brain regions of Journal of Nature Conservator. 16(1), Rana tigrina 211-15. Metabolites alteration in systemic circulation during CFA cum Journal of Nature Conservator. 15(1): IFA induced arthritogenesis in Rattus norvegicus 183-190. Enzymes activity and trace elements concentration in Journal of Nature Conservator. 15(1): systemic circulation during CFA cum IFA induced 151-158. arthritogenesis in Rattus norvegicus CFA without booster dose of adjuvant (IFA) in arthritogenesis Uttar Pradesh Journal of Zoology. and the role of neuronal organ, in Wistar rats Rattus 23 (1): 57-65. norvegicus Effect of DDT, Malathion and Mercury on the Hematology of Journal of Ecobiology. Sarotherodon mossambicus 13(2): 159-160. Sex differences in delayed hypersensitivity response in Uttar Pradesh Journal of Zoology. Wistar rats Rattus norvegicus to CFA 22(1): 85-88. Agglutinating property of cell free haemolymph (serum) of Uttar Pradesh Journal of Zoology. Penaeus monodon to RBCs, bacteria and yeast 22(3): 231-236. Significance of CFA induced inflammatory changes on tissue Academic Science Letters. metabolites and enzymes in Rattus norvegicus 23: (5-6) 86-92. Serum proteins and hematological profile for prolonged Journal of Ecotoxicol & Environmental immunogenecity of adjuvant induced rheumatoid arthritis in Monitoring. Rattus norvegicus 11(2): 141-145. Significance of differential distribution on lactate and lactate Journal of Ecobiology. dehydrogenase activity in the muscular regions of Scylla 12(3): 229-232. tranquebarica