Qing-Yuan Sun’s CV
Born:
Dec 4, 1964, Shandong Province, P.R. China
Marital status:
married with 2 children
Current address:
State Key Laboratory of Reproductive Biology
Institute of Zoology
Chinese Academy of Sciences
Datun Rd., Chaoyang District, Beijing 100101
P.R. China
E-mail:
sunqy@ioz.ac.cn; sunqy1@yahoo.com
Tel:
0086-10-64807050 (O)
Fax:
0086-10-64809050/64807316
Education, training and working experience (from Ph.D.):
1991.09-1994.07
Northeast Agricultural University, Harbin, Animal Embryology, Doctor of Science
1994.08-1996.08
Institute of Zoology, Chinese Academy of Sciences, post-doc
National Institute of Animal Industry, Japan, STA fellow
1996.10-1998.05
Bar-Ilan University, Israel, post-doc
1999.10-2001.08
University of Missouri-Columbia, USA, research associate
2003.03-2003.04
National institute of Agrobiological Sciences, Japan
Invited JSPS fellow
2005.05-2005.08
University of Missouri-Columbia, USA, Visiting professor
2008.04-2008.06
National institute of Agrobiological Sciences, Japan
Invited JSPS fellow
2009.04-2009.07
University of Missouri-Columbia, USA, Visiting professor
1996.09-present
Associate professor (1996.09-1998.11)
Full professor (1998.12-present)
Director, Center for Reproduction, Development and Aging (2002-2006)
Director, State Key Laboratory of Reproductive Biology Institute of Zoology,
Chinese Academy of Sciences(2006-present)
Research fields:
1.
Signal transduction, spindle organization, spindle checkpoint, and chromosome separation during oocyte
-1-
meiotic maturation and fertilization
2.
Assisted reproduction technology and animal cloning
3.
Epigenetics in early development
Editorial Board member:
Biology of Reproduction, editorial board (reviews committee) member (USA, 2007--2009)
Biology of Reproduction, member of board of reviewing editors (USA, 2009--)
Cell Cycle, editorial board member (USA, 2007--)
Reproduction, Fertility and Development, Associate editor (handling)(Australia, 2009---)
Molecular Reproduction and Development, associate editor (USA, 2007--2009)
Journal of Reproduction and Development, editorial board member (Japan, 2004--)
Asian Journal of Andrology, editorial board member (China,2004--)
Progress in Natural Science, editorial board member (China, 2004--)
Progress in Biophysics and Biochemistry (China, 2010--)
Acta Zool Sin, editorial board member (China,2000--)
Chinese J Zool, editorial board member (China,2000--)
J Reproductive Med, editorial board member (China,2001--)
Chinese Journal of Cell Biology, editorial board member (China,2007--)
Current Zoology, editor (China,2009--)
Heredity, associate editor (China, 2010--)
Centrosome Research. Editorial board member (USa, 2011--)
Reproductive Biotechnology, associate editor (Japan, 2011--)
Expert reviewer:
Peer-review Journals:
Nature Protocols
Human Reproduction Update
Journal of Cell Science
Endocrinology
Developmental Biology
Biology of Reproduction
Human Reproduction
Molecular Human Reproduction
-2-
Fertility and Sterility
PLoS ONE
Reproduction
Molecular Reproduction and Development
BMC Developmental Biology
International Journal of Developmental Biology
Developmental Dynamics
Theriogenology
Journal of Cellular Physiology
Cell Cycle
Cell Proliferation
Animal Biology
Proteomics
The American Journal of Physiology - Endocrinology and Metabolism
Trends in Molecular Medicine
BMC Cell Biology
Vaccine
Histochemistry and Cell Biology
Journal of Molecular Endocrinology
Journal of Proteome Research
Cloning and Stem Cells
Molecular Biology Reports
Frontiers in Bioscience
Zygote
Microscopy and Microanalysis
Clinica Chimica Acta
Reproduction, Fertility and Development
Journal of Reproduction and Development
Reproduction in Domestic Animals
Reproductive Biology and Endocrinology
DNA and Cell Biology
Microscopy Research and Technique
Journal of Clinical Medicine and Research
-3-
Cell and Tissue Research
International Journal for Biotechnology and Molecular Biology Research
Developmental and Reproductive Biology
Current Zoology
(Other 27 journals in Chinese are not listed)
Grants:
National Natural Science Foundation of China
Ministry of Science and Technology, China
Natural Science Foundation of Beijing
Wellcome Trust Foundation, UK
Czech Science Foundation, Czech Republic
Awards and honors:
1999, Distinguished Young Scientist, Chinese Academy of Sciences
2002, Distinguished Young Scientist Grant, National Natural Science foundation of China
2003, One of the Ten Outstanding Youths, Chinese Academy of Sciences
2003, National Award for Distinguished Scholars Returned from Abroad
2003, Science and Technology Progress Prize, Xinjiang (1st class, 3rd contributor)
2004, National Distinguished Talents of the New Century
2004, National Award for Distinguished Young Scientists
2005, National Award for Distinguished Youth with Post-doc Experience
2005, Chinese Government Special Expert Allowance
2005, National Natural Science Prize (second class，second contributor)
2006, National Population and Family Planning Council Science and Technology advancement First Prize
(second contributor)
2006, Outstanding Teacher of the Chinese Academy of Sciences Graduate School
2006, Distinguished researcher of the National Population and Family Planning Council
2007，Awardees of Hundred Talents Program of the Chinese Academy of Sciences
2007, BHP Billiton Supervisor Research Award, Graduate School of Chinese Academy of Sciences
2009, Member, Academic Degree Committee，The State Council of China
2011, Outstanding contributor for the National “11th-Five-Year” Science and Technology Programs
Social work:
-4-
President, Chinese Society for Cellular and Molecular Microscopy
Secretary General, Chinese Society for Reproductive Biology
Vice-president, Chinese Society for Zoology
Invited talks (after 2003)
1.
Workshop: From Egg to Fertilization: Involvement of MAPK cascade during mammalian oocyte
maturation and fertilization, 2003, Kobe University, Japan
2.
Invited talk: Regulation of MAPK cascade on oocyte maturation and fertilization, 2003, Tsukuba, National
Institute of Agrobiological Sciences, Japan
3.
Cross-Strait Symposium on Comparative Endocrinology and Reproductive Biology: The role of MAPK
and its regulation during mammalian oocyte maturation and fertilization, 2003, Taiwan, China
4.
International Young Scientists Forum on Modern Reproductive Biology and Biotechnology: Involvement
of mitogen-activated protein kinase cascade during oocyte maturation and fertilization in mammals, 2004,
Huhhot, Inner Mongolia University, China
5.
International Symposium on Reproductive Medicine: Oocyte Growth and Maturation, 2004, Jinan,
Shandong University, China
6.
Symposium and Workshop of In Vitro Maturation (IVM) of Human Oocytes: Oocyte growth and
maturation, 2004, Nanjing, Nanjing Medical University, China
7.
The First Russian-Chinese Symposium of Young Scientists “The Science about Life”: Regulation of oocyte
maturation and fertilization by MAPK cascade, 2004, Pushchino, Russian Academy of Sciences, Russia
8.
2004 KRIBB conference: oocyte maturation workshop: MAPK cascade regulation on pig oocyte
maturation and fertilization, 2004, Daejeon, The Korea Research Institute of Bioscience and Biotechnology,
Korea
9.
The 4th International Symposium of Developmental Biology: The role of MAPK cascade and its regulation
during pig oocyte maturation and fertilization, Suwan, 2004, Korea
10. Invited talk: The role of MAPK pathway during pig oocyte maturation and fertilization. Institute of
Genetics and Developmental Biology, Chinese Academy of Science, Beijing, 2005
11. Microscopy and Microanalysis 2005 Meeting: The regulation of microtubule assembly by small GTPase
Ran in mouse oocyte. 2005, Hawaii, USA
12. First Sino-Canada Bilateral Workshop on Reproductive Health Research: Involvement of mitogen-activated
protein kinase during oocyte meiotic maturation in mammals, 2005, Beijing
13. The 6th Sapporo International Symposium on Ovarian Function: The role of MAPK cascade during pig
oocyte maturation , 2006, Otaru, Japan
-5-
14. Invited talk: MAPK activation in cumulus cells but not in oocyte is required for stimulating ooycte meiotic
resumption. China Medical University, 2006, Shenyang
15. Special invited talk: The role of MAPK in pig oocyte maturation. 2006, Rho International Symposium,
Seoul, Korea
16. 3rd Asian Reproductive Biotechnology Conference: Mitogen-activated protein kinase (MAPK) in pig
oocyte maturation. 2006, Hanoi, Vietnam (chairperson)
17. The second Animal Biotechnology Conference: The role of MAPK in porcine oocyte maturation. 2006,
Nanning
18. Tsukuba Animal Biotechnology Meeting: DNA hypomethylation in aborted bovine clones. Tsukuba, 2007
(chairperson)
19. 33rd Annual Conference of the IETS (International Embryo Transfer Society): Evaluation of oocyte quality:
morphological, cellular and molecular predictors. 2007, Kyoto, Japan
20. United Conference of Chinese Society of Reproductive Medicine and Chinese Society of Reproductive
Biology：Evaluation of oocyte quality: morphological, cellular and molecular predictors. 2007, Hangzhou
21. Invited talks: 1) Evaluation of oocyte quality: morphological, cellular and molecular predictors. 2) The role
of mitogen-activated protein kinase (MAPK) in pig oocyte maturation, 2007, Northwest A&F University,
Yangling
22. Invited talks: The role of mitogen-activated protein kinase (MAPK) cascade during in oocyte maturation.
2007, Beijing Institute of Animal Science and Veterinary Medicine, Beijing
23. International Young Scientist Forum on Mammalian Reproductive Biotechnology: MEK1/2 function and
transportation during mouse oocyte meiotic maturation. 2007, Hohhot
24. Symposium of Epigenetics:Somatic Cell cloning and abnormalities in DNA methylation, 2007, Yantai
25. 07’ International Workshop on Repeated Failure of IVF-ET: Oocyte meiotic spindle checkpoint, 2007,
Guangzhou
26. Second Sino-Cananda Bilateral Workshop on Reproductive Health Research: The role of MEK1/2 during
mouse oocyte meiotic maturation, 2007, Ottawa, Cananda (co-chair)
27. The 4th Annual Conference of Asian Reproductive Biotechnology Society: MEK1/2 function and
transportation during mouse oocyte meiotic maturation. 2007, Singapore (session chair)
28. 2008 Beijing International Congress on Human Reproductive Medicine: DNA methylation, embryo
development and assisted reproduction, 2008, Beijing.
29. Invited talk: Regulation of chromosome separation during oocyte meiosis. 2008, Azabu University, Japan
30. Invited talk: Regulation of chromosome separation during oocyte meiosis. 2008, Hiroshima University,
Japan
-6-
31. 08’International Seminar on Repeated Failure of IVF: Oogenesis, follicular recruitment and superovulation,
2008, Guanzhou(session Chair)
32. Invited talk: Oogenesis and follicular development, Qingdao Agricultural University, 2008, Qingdao.
33. International Seminar on Frontiers in ART: Chromosome separation regulation during oocyte meiosis, 2008,
Hefei
34. International Workshop on “Recent Progress in Reproductive Biology”: Chromosome division during
oocyte meiosis, 2008 Beijing.
35. The 8th International Symposium on Developmental Biotechnology: Molecular insights into mechanisms
regulating faithful chromosome reparation during mouse oocyte meiosis. 2008, Korea.
36. Invited talk: Molecular insights into mechanisms regulating faithful chromosome reparation during mouse
oocyte meiosis. 2008,Chunbuk Natioanl University, Korea.
37. The 5th Asian Reproductive Biotechnology Conference： Molecular insights into mechanisms regulating
faithful chromosome reparation during mouse oocyte meiosis. 2008, Kunming
38. The 14th Meeting of China Cellular and molecular Micrsocopy Society: Mechanisms regulating
chromosome segregation in oocyte meiosis. Harbin, 2009.
39. Invited talk: Molecular insights into mechanisms regulating faithful chromosome reparation during mouse
oocyte meiosis. 2009, KonKuk University, Korea
40. The 6th Asian Reproductive Biotechnology Conference: Mechanisms regulating accurate chromosome
segregation during oocyte meiosis. 2009, Cambodia
41. Symposium on Laboratory Approaches and Clinical Intervention of Repeated IVF failure: How to design
experiment for reproductive biomedicine research and how to write scientific papers. 2009, Guangzhou
42. The 3rd Sino-Canada Bilateral Symposium on Reproductive Health： Mechanisms regulating accurate
chromosome segregation during oocyte meiosis. 2009, Nanjing.
43. Invited talk: Mechanisms regulating accurate chromosome segregation during oocyte meiosis. 2009,
Beijing, Capital Teachers’ University
44. Invited talk: Mechanisms regulating accurate chromosome segregation during oocyte meiosis. 2009, The
University of Hong Kong
45. Invited talk: The role of mitogen-activated protein kinase (MAPK) cascade during in oocyte maturation.
2009, The University of Hong Kong
46. Invited talk: Oocyte meiotic maturation, fertilization and assisted reproduction. 2010, Henan University
47. SKLRB Symposia on periimplantation biology: Mechanisms regulating accurate chromosome segregation
during oocyte meiosis. 2010, Beijing
48. 3rd International Congress on Reproductive Endocrinology and Genetics: Mechanisms regulating faithful
-7-
chromosome segregation during oocyte meiosis. 2010, Hangzhou
49. Symposium on Sterility and Reproduction in Earthquake Area: Reason for low fertility of advanced age
women and possible approaches for reproductive ability reconstruction, 2010, Chengdu
50. 2010 Symposium on Developmental Biology：p38α MAPK Is a MTOC-Associated Protein Regulating
Spindle Assembly, Spindle Length and Accurate Chromosome Segregation during Mouse Oocyte Meiotic
Maturation. 2010，Beijing
51. Symposium on Frontiers in Reproductive Medicine: Oocyte meiotic spindle organization, spindle
checkpoint and chromosome segregation, 2010, Guangzhou
52. The 5th National Animal Biotechnology Conference: Oocyte meiotic spindle organization, spindle
checkpoint and chromosome segregation, 2010, Beijing
53. The 2nd SKLAB International Symposium on “Recent progress in Reproductive Biology”：Evaluation of
oocyte quality, 2010, Beijing
54. The 7th Annual Conference of Asian Reproductive Biotechnology Society: p38α MAPK Is a
MTOC-Associated Protein Regulating Spindle Assembly, Spindle Length and Accurate Chromosome
Segregation during Mouse Oocyte Meiotic Maturation. 2010, Malaysia
55. Invited talk: Oocyte meiotic spindle organization, spindle checkpoint and chromosome segregation, 2010,
Shandong Teachers University
56. Invited talk: Meiotic spindle organization, spindle checkpoint and chromosome segregation during
mammalian oocyte maturation, 2011, Guangxi University.
Main publications in peer-reviewed international journals (*correspondence)
Review articles (*correspondence)
1.
Sun QY (2011) Ndc80 complex: New evidence for the existence of spindle assembly checkpoint in
mammalian oocyte meiosis. Cell Cycle. 2011 Mar 15;10(6):877-8.
2.
Schatten H*, Sun QY* (2010) The role of centrosomes in fertilization, cell division and establishment of
asymmetry during embryo development. Seminars in Cell & Developmental Biology. 21:174-184.
3.
Gu L, Wang Q*, Sun QY* (2010) Histone modifications during mammalian oocyte maturation: dynamics,
regulation, and functions. Cell Cycle 2010 May 23;9(10). [Epub ahead of print]
4.
Sun QY*, Miao YL, Schatten H* (2009) Towards a new understanding on the regulation of mammalian
oocyte meiosis resumption. Cell Cycle 2009 Sep 1;8(17):2741-7.
5.
Miao YL, Kikuchi K, Sun QY*, Schatten H*
(2009) Oocyte aging: implications for developmental
potential, and practical significance for assisted reproduction technologies. Human Reproduction Update
15:573-585.
-8-
6.
Schatten H, Sun QY (2009) The functional significance of centrosomes in mammalian meiosis, fertilization,
development, nuclear transfer, and stem cell differentiation. Environ Mol Mutagen. 50(8):620-36
7.
Ai JS, Li M, Schatten H, Sun QY* (2009) Regulatory mechanism of spindle movements during oocyte
meiotic division. Asian-Aust. J. Anim. Sci. 22: 1477 -1481.
8.
Sun QY, Liu K, Kikuchi K (2008) Oocyte-specific knockout: a novel in vivo approach for studying gene
functions during folliculogenesis, oocyte maturation, fertilization, and embryogenesis. Biology of
Reproduction 79:1014-1020.
9.
Yin S, Sun XF, Schatten H, Sun QY* (2008) Molecular insights into mechanisms regulating faithful
chromosome separation in female meiosis. Cell Cycle 7:2997-3005.
10. Liang CG, Su YQ, Fan HY, Schatten H, Sun QY* (2007) Mechanisms regulating oocyte meiotic
resumption: roles of mitogen-activated protein kinase. Molecular Endocrinology 21:2037-2055.
11. Sun QY, Schatten H (2006) Regulation of dynamic events by microfilaments during oocyte maturation and
fertilization. Reproduction 131:193-205.
12. Fan HY，Sun QY* (2004) Involvement of MAPK cascade during oocyte maturation and fertilization in
mammals. Biology of Reproduction 70:535-547.
13. Wang Q, Sun QY*(2007)Evaluation of oocyte quality: morphological, cellular and molecular predictors.
Reproduction Fertility and Development 19:1-12. (cover paper)
14. Sun QY, Schatten H (2007) Centrosome inheritance after fertilization and nuclear transfer. Adv Exp Med
Biol. 591:58-71
15. Sun QY and Schatten H (2006) role of NuMA in vertebrate cells: review of an intriguing multifunctional
protein. Frontiers in Bioscience 11: 1137-1146.
16. Wang WH, Sun QY* (2006) Meiotic spindle, spindle checkpoint and embryonic aneuploidy. Frontiers in
Bioscience 11:620-636.
17. Schatten H, Prather RS, Sun QY (2005) The significance of mitochondria for embryo development in
cloned farm animals. Mitochondrion 5:303-321.
18. Huo LJ，Fan HY，Chen DY，Sun QY* (2004) Function and interaction of maturation-promoting factor and
mitogen-activated protein kinase during meiotic maturation and fertilization of oocyte. Progress in Natural
Science 14:562-567.
19. Sun QY，Nagai T (2003) Molecular mechanisms underlying pig oocyte maturation and fertilization. Journal
of Reproduction and Development 49:347-359.
20. Fan HY, Huo LJ, Sun QY* (2003) Roles of calmodulin-dependent protein kinase II in meiotic maturation
and fertilization of oocytes. Prog Biochem Biophys 30:171-174.
21. Sun QY (2003) Cellular and molecular mechanisms leading to cortical reaction and polyspermy block in
-9-
mammalian eggs. Microscopy Research and Technique 61:342-348.
22. Fan HY, Tong C, Chen DY, Sun QY* (2003) Roles of protein kinase C in oocyte meiotic maturation and
fertilization. Progress in Natural Science 13:402-406.
23. Fan HY, Tong C, Chen DY, Sun QY* (2002) Roles of MAP kinase signaling pathway in oocyte meiosis.
Chinese Science Bulletin 47:1157-1162.
24. Sun QY, Breitbart H and Schatten H (1999) Role of the MAPK cascade in mammalian germ cells.
Reproduction, Fertility and Development 11: 443-450.
Major full research papers published in peer-reviewed international journals (*correspondence)
1.
Liang XW, Ge ZJ, Wei L, Guo L, Han ZM, Schatten H, Sun QY* (2011) The effects of postovulatory aging
of mouse oocytes on methylation and expression of imprinted genes at mid-term gestation. Mol Hum
Reprod. 2011 Mar 22. [Epub ahead of print]
2.
Tong JS, Zhang QH, Huang X, Fu XQ, Qi ST, Wang YP, Hou Y, Sheng J, Sun QY* (2011) Icaritin Causes
Sustained ERK1/2 Activation and Induces Apoptosis in Human Endometrial Cancer Cells. PLoS One
8;6(3):e16781.
3.
Sun SC, Sun QY, Kim NH
(2011) JMY is required for asymmetric division and cytokinesis in mouse
oocytes. Mol Hum Reprod. 2011 Jan 25. [Epub ahead of print]
4.
Huang X, Tong JS, Wang ZB, Yang CR, Qi ST, Guo L, Ouyang YC, Quan S, Sun QY, Qi ZQ, Huang RX,
Wang HL (2011) JNK2 Participates in Spindle Assembly during Mouse Oocyte Meiotic Maturation.
Microsc Microanal. 2011 Jan 31:1-9.
Publications in 2010
1.
Yang CR, Miao DQ, Guo L, Tong JS, Huang X, Hou Y, Schatten H, Li ZH*, Sun QY* (2010) Short-term
preservation of porcine oocytes in ambient temperature: novel approaches. PLoS ONE 5 (12) e14242.
2.
Tong JS, Zhang QH, Wang ZB, Li S, Yang CR, Fu XQ, Hou Y, Wang ZY, Sheng J, Sun QY* (2010)
ER-α36, a Novel Variant of ER-α, Mediates Estrogen-Stimulated Proliferation of Endometrial Carcinoma
Cells via the PKCδ/ERK Pathway. PLoS One 2010 Nov 4;5(11):e15408.
3.
Li S, Ou XH, Wang ZB, Xiong B, Tong JS, Wei L, Li M, Yuan j, OuYang YC, Hou Y, Schatten H, Sun
QY* (2010) ERK3 Is Required for Metaphase-Anaphase Transition in Mouse Oocyte Meiosis. PLoS ONE
5(9) e13074
4.
Ou XH, Li S, Xu BZ, Wang ZB, Quan S, Li M, Zhang QH, Ouyang YC, Schatten H, Xing FQ*, Sun QY*
(2010) p38α MAPK Is a MTOC-Associated Protein Regulating Spindle Assembly, Spindle Length and
Accurate Chromosome Segregation during Mouse Oocyte Meiotic Maturation. Cell Cycle 9:4130-4143.
(Faculty of 1000)
- 10 -
5.
Yaun J, Xu BZ, Qi ST, Tong JS, Wei L, Li M, Ouyang YC Hou Y, Schatten H, Sun QY * (2010)
MAPK-activated
protein
kinase
2
is
required
for
mouse
meiotic
spindle
assembly
and
kinetochore-microtubule attachment. PLoS ONE 28;5(6):e11247.
6.
Wang ZB, Ou XH, Tong JS, Li S, Wei l, Ouyang YC, Hou Y, Schatten H, Sun QY * (2010) The SUMO
pathway functions in mouse oocyte maturation. Cell Cycle Jul 19;9(13):2640-2046.
7.
Zhang QH, Wei L, Tong JS, Qi ST, Li S, Ou XH, Ouyang YC, Hou Y, An LG, Schatten H, Sun QY*
(2010) Localization and function of mSpindly during mouse oocyte meiotic maturation. Cell Cycle. 2010
Jun 25;9(11):2230-2236.
8.
Chang G, Miao YL, Zhang Y, Liu S, Kou Z, Ding J, Chen DY, Sun QY*, Gao S* (2010) Linking
incomplete reprogramming to the improved pluripotency of murine embryonal carcinoma cell-derived
pluripotent stem cells. PLoS ONE 26;5(4):e10320.
9.
Zhu JL, Lin SL, Li m, Ouyang YC, Hou Y, Schatten H, Sun QY* (2010) Septin2 is modified by
SUMOylation and required for chromosome congression in mouse oocytes. Cell Cycle 9(8) 1607-1616.
10. Lin SL, Yan LY, Qiao J, Wang ZY, Sun QY *.(2010) ER-α36, a Variant of ER-α, Promotes Tamoxifen
Agonist Action in Endometrial Cancer Cells via the MAPK/ERK and PI3K/Akt Pathways. PLoS ONE
5(2):e9013.
11. Wei L, Liang XW, Zhang QH, Li M, Yuan J, Li S, Sun SC, Ouyang YC, Schatten H, Sun QY * (2010)
BubR1 is a spindle assembly checkpoint protein regulating meiotic cell cycle progression of mouse oocyte.
Cell Cycle 9(6) 1112-1121. (Cover paper)
12. Zhu JQ, Zhu L, Liang XW, Xing FQ, Schatten H, Sun QY* (2010) Demethylation of LHR in
dehydroepiandrosterone-induced mouse model of polycystic ovary syndrome. Mol Hum Reprod
16:260-266.
13. Sha W, Xu BZ, Li M, Liu D, Feng HL, Sun QY* (2010) Impact of gonadotrophins on oocyte maturation in
vitro: An animal model. Fertility and Sterility 93(5):1650-1661.
14. Lin SL, Qi ST, Sun SC, Wang YP, Schatten H, Sun QY* (2010) PAK1 regulates spindle microtubule
organization during oocyte meiotic maturation. Front Biosci (Elite Ed). 2010 Jun 1;2:1254-64.
15. Sun SC, Lin SL, Zhang DX, Lu SS, Sun QY, Kim NH (2010) Borealin regulates bipolar spindle formation
but may not act as chromosomal passenger during mouse oocyte meiosis. Front Biosci (Elite Ed). 2010 Jun
1;2:991-1000.
16. Wang J, Zhang M, Zhang Y, Kou Z, Han Z, Chen DY, Sun QY, Gao S. (2010) The Histone Demethylase
JMJD2C Is Stage-Specifically Expressed in Preimplantation Mouse Embryos and Is Required for
Embryonic Development. Biol Reprod. 82:105-111.
17. Qiao J, Chen Y, Yan LY, Yan J, Liu P, Sun QY (2010) Changes in histone methylation during human oocyte
- 11 -
maturation and IVF- or ICSI-derived embryo development. Fertil Steril. 93(5):1628-36
18. Ma CH, Yan LY, Qiao J, Sha W, Li L, Chen Y, Sun QY (2010) Effects of tumor necrosis factor-alpha on
porcine oocyte meiosis progression, spindle organization, and chromosome alignment. Fertil Steril.
93:920-926.
Publications in 2009
1.
Li M, Li S, Yuan J, Wang ZB, Sun SC, Schatten H, Sun QY* (2009) Bub3 Is a Spindle Assembly
Checkpoint Protein Regulating Chromosome Segregation during Mouse Oocyte Meiosis. PloS ONE
4:e7701.
2.
Yuan J, Sun QY*. (2009) Astrin regulates meiotic spindle organization, spindle pole tethering and cell
cycle progression in mouse oocytes. Cell Cycle 8(20) 3384-3395.
3.
Sun Y, Kucej M, Fan HY, Yu H, Sun QY, Zou H (2009) Separase is recruited to mitotic chromosomes to
dissolve sister chromatid cohesion in a polynucleotide-dependent manner. Cell 137:123-132.
4.
Lin SL, Yan LY, Liang XW, Wang ZB, Wang ZY, Qiao J, Heide Schatten, Sun QY* (2009) A novel variant
of ER-alpha, ER-alpha36 mediates testosterone-stimulated ERK and Akt activation in endometrial cancer
Hec1A cells. Reproductive Biology and Endocrinology 7:102.
5.
Sun SC, Wei L, Li M, Lin SL, Xu BZ, Liang XW, Kim NH, Schatten H, Lu SS, Sun QY*
(2009 )Perturbation of survivin expression affects chromosome alignment and spindle checkpoint in mouse
oocyte meiotic maturation. Cell Cycle 8(20) 3365-3372.
6.
Yan LY, Qiao J, Chen Y, Huang J, Liu P, Sun QY (2009) Application of 3D- fluorescence in situ
hybridization to human preimplantation genetic diagnosis. Fertility and Sterility 92(4):1492-5.
7.
Miao YL, Sun QY, Zhang X, Zhao JG, Zhao MT, Spate L, Prather RS, Schatten H (2009).Centrosome
Abnormalities During Porcine Oocyte Aging. Environmental and Molecular Mutagenesis 2009
50(8):666-71..
8.
Xu BZ, Lin SL, Li M, Zhu JQ, Li S, Ouyang YC, Chen DY, Sun QY* (2009) Changes in estrogen receptor
ER-alpha36 expression during mouse ovary development and oocyte meiotic maturation. Histochemistry
and Cell Biology 131:347–354.
9.
Xu BZ, Li M, Xiong B, Lin SL, Zhu JQ, Hou Y, Chen DY, Sun QY*. (2009) Involvement of
calcium/calmodulin-dependent protein kinase kinase in meiotic maturation of pig oocytes. Anim Reprod
Sci. 111(1):17-30.
Publications in 2008
1.
Yin S, Ai JS, Shi LH, Wei L, Yuan J, OuYang YC, Hou Y, Chen DY, Schatten H, Sun QY* (2008)
Shugoshin1 may play important roles in separation of homologous chromosomes and sister chromatids
during mouse oocyte meiosis. PLoS ONE 3(10):e3516.
- 12 -
2.
Li M, Yin S, Yuan J, Wei L, Ai JS, Hou Y, Chen DY, Sun QY* (2008) Testosterone potentially triggers
meiotic resumption by activation of intra-oocyte SRC and MAPK in porcine oocytes. Biology of
Reproduction 79: 897-905.
3.
Xiong B, Li S, Ai JS, Yin S, OuYang YC, Sun SC, Chen DY, Sun QY* (2008) BRCA1 is required for
meiotic spindle assembly and spindle assembly checkpoint activation in mouse oocytes. Biology of
Reproduction 79(4):718-726.
4.
Li M, Yin S, Yuan J, Wei L, Ai JS, HouY, Chen DY and Sun QY* (2008) Cdc25A promotes G2/M
transition in oocytes. Cell Cycle 16;7(9) :1301-1302.
5.
Wang Q, Ai JS, Ola SI, Gu L, Zhang YZ, Chen DY and Sun QY* (2008) The spatial relationship between
Heterochromatin Protein 1 alpha and histone modifications during mouse oocyte meiosis. Cell Cycle
7(4):513-520.
6.
Liu JH, Zhu JQ, Liang XW, Yin S, Ola SI, Hou Y, Chen DY, Schatten H, Sun QY* (2008) Diploid
parthenogenetic embryos adopt a maternal type methylation pattern on both sets of maternal chromosomes.
Genomics 91:121-128
7.
Liang XW, Zhu JQ, Miao YL, Liu JH, Wei L, Lu SS, Hou Y, Schatten H, Lu KH, Sun QY* (2008) Loss of
methylation imprint of Snrpn in postovulatory aging mouse oocyte. Biochemical and Biophysical Research
Communications 371:16-21.
8.
Wang L，Wang Z, Zhang X, Harris GF, Baltz JM, Sun QY, Liu XJ (2008) Brefeldin A disrupts asymmetric
spindle positioning in mouse oocytes. Developmental Biology 313:155-166.
9.
Xiong B, Sun SC, Lin SL, Li M, Xu BZ, OuYang YC, Hou Y, Chen DY, Sun QY* (2008) Involvement of
Polo-like kinase 1 in MEK1/2-regulated spindle formation during mouse oocyte meiosis. Cell Cycle
7:1795-1803.
10. Liu JH, Liang XW, Zhu JQ, Wei L, Hou Y, Chen DY, Sun QY* (2008) Aberrant DNA methylation in 5’
regions of DNA methyltransferase genes in aborted bovine clones. Journal of Genetics and Genomics
35:559-568.
11. Ai JS, Wang Q, Yin S, Shi LH, Xiong B, OuYang YC, Hou Y, Chen DY, Schatten H, Sun QY* (2008)
Regulation of Peripheral Spindle Movement and Spindle Rotation during Mouse Oocyte Meiosis: New
Perspectives. Microscopy and Microanalysis 14:349-356.
12. Zhong Z, Hao Y, Li R, Spate L, Wax D, Sun QY, Prather RS, Schatten H (2008) Analysis of heterogeneous
mitochondria distribution in somatic cell nuclear transfer porcine embryos. Microsc Microanal.
14(5):418-32.
13. Ola SL, Ai JS, Liu JH, Wang Q, Wang ZB, Chen DY, Sun QY* (2008) Effects of gonadotrophins, growth
hormone and activin A on enzymatically isolated follicle growth, oocyte chromatin organization and steroid
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secretion. Mol Reprod Dev 75:89-96.
14. Liu JH, Yin S, Xiong B, Hou Y, Chen DY, Sun QY* (2008) Widespread disruption of DNA methylation
imprinting in aborted bovine clones. Mol Repord Dev 75:598-607.
15. Li M, Liang CG, Xiong B, Xu BZ, Lin SL, Hou Y, Chen DY, Schatten H, Sun QY* (2008) PI3-Kinase and
Mitogen-Activated Protein Kinase in Cumulus Cells Mediate EGF-Induced Meiotic Resumption of Porcine
Oocyte. Domestic Animal Endocrinology 34:360-371.
16. Zhu JQ, Liu JH, Liang XW, Xu BZ, Hou y, Zhao XX, Sun QY* (2008) Heat stress causes aberrant DNA
methylation of H19 and Igf-2r in mouse blastocysts. Molecules and Cells 25:211-215.
17. Zhang YZ, OuYang YC, Hou Y, Schatten H, Chen DY, Sun QY* (2008) Mitochondrial behavior during
oogenesis in zebrafish: A confocal microscopy analysis. Dev Growth Differ 50(3):189-201
18. Ai JS, Wang Q, Li M, Shi LH, Ola SI, Xiong B, Yin S, Chen DY, Sun QY*. (2008) Roles of microtubules
and microfilaments in spindle movements during rat oocyte meiosis. J Reprod Dev. 54:391-396.
19. Gu L, Wang Q, Hong Y, Sun SG, Yang SY, Wang JG, Hong Y, Sun QY*, Liu WQ (2008) Distribution and
expression of phosphorylated histone H3 during porcine oocyte maturation. Mol Reprod Dev 75:143-149.
20. Sun SC, Xiong B, Lu SS, Sun QY* (2008)MEK1/2 is a critical regulator of microtubule assembly and
spindle organization during rat oocyte meiotic maturation. Mol Reprod Dev 75(10):1542-1548.
21. Shi LH, Miao YL, Ouyang YC, Huang JC, Lei ZL, Yang JW, Han ZM, Song XF, Sun QY, Chen DY. (2008)
Trichostatin A (TSA) improves the development of rabbit-rabbit intraspecies cloned embryos, but not
rabbit-human interspecies cloned embryos. Developmental Dynamics 237(3):640-8
22. Shi LH, Ai JS, Ouyang YC, Huang JC, Lei ZL, Wang Q, Yin S, Han ZM, Sun QY, Chen DY. (2008)
Trichostatin A and nuclear reprogramming of cloned rabbit embryos. J Anim Sci. 86:1106-1113.
23. Lei ZL, Huang JC, Shi LH, Miao YL, Nan CL, Yang JW, Ouyang YC, Sun QY, Chen DY (2008) Full term
development of normal mice after transfer of IVF embryos derived from oocytes stored at room
temperature for 1 day. Zygote 16(1):21-7.
24. Zhang G, Sun QY, Chen DY (2008) Effects of sucrose treatment on the development of mouse nuclear
transfer embryos with morula blastomeres as donors. Zygote 16(1):15-9.
25. Zhang G, Sun QY, Chen DY (2008) In vitro development of mouse somatic nuclear transfer embryos:
effects of donor cell passages and electrofusion. Zygote 26:1-5.
26. Lei ZL, Huang JC, Shi LH, Miao YL, Nan CL, OuYang YC, Sun QY, Chen DY (2008) Development of
normal mice after microinjection of round spermatids into oocytes stored at room temperature for one day.
Mol Reprod Dev 75:795-800.
Publications in 2007
1.
Yin S, Liu JH, Ai JS, Xiong B, Wang Q, Hou Y, Chen DY, Sun QY* (2007) Cdc20 is required for the
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anaphase onset of the first meiosis but not the second meiosis in mouse oocytes. Cell Cycle 23：2990-2992.
2.
Xiong B, Yu LZ, Wang Q, Ai JS, Yin S, Liu JH, OuYangYC, Houn Y, Chen DY, Sun QY* (2007)
Regulation of intracellular MEK1/2 translocation in mouse oocytes: cytoplasmic dynein/dynactin-mediated
poleward transport and cyclin B degradation-dependent release from spindle poles. Cell Cycle
6(12):1521-1527. (cover paper)
3.
Yu LZ, Xiong B, Gao WX, Wang CM, Zhong ZS, Huo LJ, Wang Q, Hou Y, Liu K, Liu J, Schatten H, Chen
DY, Sun QY* (2007) MEK1/2 regulates microtubule organization, spindle pole tethering and asymmetric
division during mouse oocyte meiotic maturation. Cell Cycle 6(3):330-338.
4.
Zhang D, Yin S, Jiang MX, Ma W, Hou Y, Cheng-Guang Liang CG, Yu LZ, Wang WH, Sun QY* (2007)
Cytoplasmic dynein participates in meiotic checkpoint pathway in mouse oocytes by transporting
checkpoint proteins between cytoplasm and kinetochores. Reproduction 133: 685-695.
5.
Ola SI, Wang Q, Ai JS, Liang CG, Yin S, Sun QY* (2007) Meiotic competence and acetylation pattern of
UV light classified mouse antral oocytes after meiotic arrest with Isobutylmethylxanthine. Mol Reprod Dev
74(5):591-599.
6.
Zhong Z， Spate L，HaoY， Li R， Lai L， Katayama M， Sun QY， Prather RS， Schatten H (2007)
Remodeling of centrosomes in intraspecies and interspecies nuclear transfer porcine embryos. Cell Cycle
6(12) 1510-1520.
7.
Feng C, Yu A, Liu Y, Zhang J, Zong Z, Su W, Zhang Z, Yu D, Sun QY, Yu B (2007) Involvement of protein
kinase B/AKT in early development of mouse fertilized eggs. Biol Reprod 77:560-568.
8.
Huang JC， Yan LY, Lei ZL, Miao YL, Shi LH, Yang JW, Wang Q, OuYang YC, Sun QY, Chen DY (2007)
Changes in Histone Acetylation During Postovulatory Aging of Mouse Oocyte. Biol Reprod 77:666-670.
9.
Yang JW, Lei ZL, Miao YL, Huang JC, Shi LH, OuYang YC, Sun QY and Chen DY (2007) Spindle
assembly in the absence of chromosomes in mouse oocytes Reproduction 134: 731–738.
10. Wang JY, Lei ZL, Nan CL, Yin S, Liu J, Hou Y, Li YL1, Chen DY, Sun QY* (2007) RNA interference as a
tool to study the function of MAD2 in mouse oocyte meiotic maturation. Mol Reprod Dev 74(1):117-125.
11. Miao YL, Shi LH, Lei ZL, Huang JC, Yang JW, OuYang YC, Sun QY*, Chen DY* (2007) Effects of
caffeine on in vivo and in vitro oocyte maturation in mice. Theriogenology 68:640-645.
12. Tang LS, Wang Q, Xiong B, Hou Y, Zhang YZ, Sun QY, Wang SY (2007) Dynamic changes in histone
acetylation during sheep oocyte maturation. J Reprod Dev 53:556-563.
13. Huang JC, Lei ZL, Shi LH, Miao YL, Yang JW, Ouyang YC, Sun QY, Chen DY (2007) Comparison of
histone modifications in in vivo and in vitro fertilization mouse embryos. Biochem Biophys Res Commun.
354(1):77-83.
14. Zhao ZJ, Li RC, Cao HH, Zhang QJ, Jiang MX, Ouyang YC, Nan CL, Lei ZL, Song XF, Sun QY, Chen
- 15 -
DY.(2007) Interspecies nuclear transfer of Tibetan antelope using caprine oocyte as recipient. Mol Reprod
Dev 74(4):412-9.
15. Zhu ZY, Sun QY, Chen DY (2007) Cytoskeletal and nuclear reorganization in mouse embryos derived from
nuclear transfer and ICSI: a comparison of agamogony and syngamy before and during the first cell cycle.
Mol Reprod Dev 74(5):655-663.
16. Nan CL, Sun QY, Chen DY (2007) Time course of meiotic progression after transferring primary
spermatocyte into ooplasm at different stages. Mol Reprod Dev 74:1072-1080.
17. Nan CL, Lei ZL, Zhao ZJ, Shi LH, Ouyang YC, Song XF, Sun QY, Chen DY (2007) Increased Th1/Th2
(IFN-gamma/IL-4) cytokine mRNA ratio of rat embryos in the pregnant mouse uterus. J Reprod Dev.
53:219-228.
Publications in 2006
1.
Wang Q, Wang CM, Ai JS, Xiong B, Yin S, Hou Y, Chen DY, Schatten H, Sun QY* (2006) Histone
phosphorylation and pericentromeric histone modifications in oocyte meiosis. Cell Cycle 5(17) 1974-1982.
2.
Yin S, Wang Q, Liu JH, Ai JS, Liang CG, Hou Y, Chen DY, Schatten H, Sun QY* (2006) Bub1 prevents
chromosome misalignment and precocious anaphase during mouse oocyte meiosis. Cell Cycle 5(18)
2130-2137.(cover paper)
3.
Xiong B, Yin S, Hou Y, Chen DY, Schatten H, Sun QY* (2006) Histone deacetylation is required for the
orderly meiotic maturation in porcine oocytes. Cell Cycle 5:766-774.
4.
Fan HY, Sun QY, Zou H (2006) Regulation of separase in meiosis: Separase is activated at the metaphase
I-II transition in Xenopus oocytes during meiosis. Cell Cycle 5(2):198-204.
5.
Huo LJ, Zhong ZS, Liang CG, Wang Q, Yin S, Ai JS, Yu LZ, Chen DY, Schatten H, and Sun QY* (2006)
Degradation of securin in mouse and pig oocytes is dependent on ubiquitin-proteasome pathway and is
required for proteolysis of the cohesion subunit, Rec8, at the metaphase-to-anaphase transition. Frontiers in
Bioscience 11:2193-2202.
6.
Chen T, Zhang YL, Jiang Y, Liu JH, Schatten H, Chen DY, Sun QY* (2006) Interspecies nuclear transfer
reveals that demethylation of specific repetitive sequences is determined by recipient ooplasm but not by
donor intrinsic property in cloned embryos. Molecular Reproduction and Development 73:313-317.
7.
Meng XQ, Zheng KG, Yang Y, Jiang MX, Zhang YL, Sun QY, and Li YL (2006) Proline-rich tyrosine
kinase2 is involved in F-actin organization, during in vitro maturation of rat oocyte. Reproduction 132:
859-867.
8.
Chen DY, Jiang MX, Zhao ZJ, Wang HL, Sun QY, Zhang LS, Li RC, Cao HH, Zhang QJ, Ma DL (2006)
Cloning of Asian Yellow Goat (C. hircus) by somatic cell nuclear transfer: telophase enucleation combined
with whole cell intra-cytoplasmic injection. Mol Reprod Dev 74(1):28-34.
- 16 -
9.
Yan LY, Huang JC, Zhu ZY, Lei ZL, Shi LH, Nan CL, Zhao ZJ, OuYang YC, Song XF, Sun QY, Chen DY
(2006)NuMA distribution and microtubule configuration in rabbit oocytes and cloned embryos.
Reproduction 132: 869-876.
10. Zhao ZJ, Ou Yang YC, Nan CL, Lei ZL, Song XF, Sun QY, Chen DY.(2006) Rabbit Oocyte Cytoplasm
Supports Development of Nuclear Transfer Embryos Derived from the Somatic Cells of the Camel and
Tibetan Antelope. J Reprod Dev. 52:449-459.
11. Liu ZH, Schatten H, HaoYH, Lai LX, Wax D, Samuel1 M, Zhong ZS, Sun QY, Prather RS (2006) The
nuclear mitotic apparatus (NuMA) protein is mainly contributed by the donor cell nucleus in cloned
porcine embryos. Frontiers in Bioscience 11:1945-1957.
12. Yan LY, Shi LH, Liu SZ, Huang JC, Zhu ZY, OuYang YC, Lei ZL, Zhong ZS, Sun QY, Chen DY (2006)
Dynamic changes in NuMA and microtubules in monkey-rabbit nuclear transfer embryos. Frontiers in
Bioscience 11: 1892-1900.
13. Jiang Y, Chen T, Wang K, Jiang MX, Liu SZ, Ouyang YC, Sun QY, Chen DY (2006) Different fates of
donor mtDNAs in bovine-rabbit and cloned bovine-rabbit reconstructed embryos during preimplantation
development. Frontiers in Bioscience 11:1425-1432.
Publications in 2005
1.
Liang CG, Huo LJ, Zhong ZS, Chen DY, Schatten H, Sun QY* (2005) cAMP-dependent activation of
MAPK in cumulus cells is essential for germinal vesicle breakdown of porcine cumulus-enclosed oocytes.
Endocrinology 144:4437-4444.
2.
Zhong ZS, Zhang G, Meng XQ, Zhang YL, Chen DY, Schatten H, Sun QY* (2005) Function of donor cell
centrosome in intraspecies and interspecies nuclear transfer embryos. Experimental Cell Research
306:35-46.
3.
Chen T, Jiang Y, Zhang YL, Liu JH, Hou Y, Schatten H, Chen DY, Sun QY*(2005) DNA hypomethylation
of individual sequences in aborted cloned bovine fetuses. Frontiers in Bioscience 10:3002-8.
4.
Reddy P, Shen L, Ren C, Boman K, Lundin E, Ottander U, Lindgren P, Liu YX, Sun QY, Liu K (2005)
Activation of Akt (PKB) and suppression of FKHRL1 in mouse and rat oocytes by stem cell factor during
follicular activation and development. Developmental Biology 281:160-170.
5.
Ma W, Zhang D, Hou Y, Li YH, Sun QY, Sun XF, Wang WH (2005) Reduced expression of MAD2, Bcl-2,
and MAP kinase activity in pig oocytes after in vitro aging are associated with defects in sister chromatid
segregation during meiosis II and embryo fragmentation after activation Biology of Reproduction
72:373-393.
6.
Huo LJ, Liang CG, Yu LZ, Zhong ZS, Yang ZM, Fan HY, Chen DY and Sun Q-Y*(2005) Inducible nitric
oxide synthase-derived nitric oxide regulates germinal vesicle breakdown and first polar body emission in
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mouse oocyte. Reproduction 129:403-409.
7.
Zhong ZS, Huo LJ, Liang CG, Chen DY, Schatten H, Sun QY* (2005) Small GTPase RhoA is required for
ooplasmic segregation, spindle rotation, but not for spindle organization and chromosome separation
during mouse oocyte maturation, fertilization, and early cleavage. Molecular Reproduction and
Development 71:256-261.
8.
Zheng ZY, Li QZ, Chen DY, Schatten H, Sun QY* (2005) Translocation of phospho-PKCs implies their
roles in meiotic spindle organization, polar body emission and nuclear activity in mouse eggs.
Reproduction 129:229-234.
9.
Zhang D, Li M, Ma W, Hou Y, Li YH, Li SW, Sun QY, Wang WH (2005) Localization of Mitotic Arrest
Deficient 1 (MAD1) in mouse oocytes during the first meiosis and its functions as a spindle checkpoint
protein. Biology of Reproduction 72:58-68.
10. Liu SZ, Yao LJ, Jiang MX, Lei ZL, Zhang YL, Sun QY, Zheng YL, Song XF, Chen DY (2005) Apoptosis
in rabbit embryos produced by fertilization or nuclear transfer with fibroblasts and cumulus cells.
Reproduction 130:359-366.
11. Zhang YL, Chen T, Jiang Y, Zhong ZS, Liu SZ, Hou Y, Schatten H, Chen DY, Sun QY* (2005) Active
demethylation of individual genes in intracytoplasmic sperm injection rabbit embryos. Molecular
Reproduction and Development 72:530-533.
12. Cao YK, Zhong ZS, Chen DY, Zhang GX, Schatten H & Sun QY* (2005) Cell cycle-dependent
localization and possible roles of small GTPase Ran in mouse oocyte maturation, fertilization and early
cleavage. Reproduction 130:431-440.
13. Yao LJ, Sun QY* (2005) Characterization of Aurora-A in porcine oocytes and embryos implies its
functional roles in regulation of meiotic maturation, fertilization and cleavage. Zygote 13:23-30.
14. Huo LJ, Sun QY*
(2005) Cell cycle dependent subcellular localization of cyclin B1，phosphorylated
cyclin B1 and p34cdc2 during oocyte meiotic maturation and fertilization in mouse. Zygote 13:45-53.
15. Wen DC, Bi CM, Xu Y, Yang CX, Zhu ZY, Sun QY, Chen DY (2005) Hybrid embryos produced by
transferring panda or cat somatic nuclei into rabbit MII oocytes can develop to blastocyst in vitro. Journal
of Experimental Zoology 303A: 689-697.
16. Zheng YL, Sun QY, Chen DY (2005) Production of mouse by inter-strain inner cell mass replacement.
Zygote 13:73-77.
17. Liu SZ, Jiang MX, Yan LY, Jiang Y, Ouyang YC, Sun QY, Chen DY (2005) Parthenogenetic and nuclear
transfer rabbit embryo development and apoptosis after activation treatments. Molecular Reproduction and
Development 72: 48-53.
18. Jiang MX, Zhu Y, Zhu ZY, Sun QY, Chen DY (2005) Effects of cooling, cryopreservation and heating on
- 18 -
sperm proteins, nuclear DNA, and fertilization capability in mouse. Molecular Reproduction and
Development 72:129-134.
19. Zhang M, Tao Y, Zhou B, Xie H, Wang F, Lei L, Huo LJ, Sun QY and Xia G (2005) Atrial natriuretic
peptide inhibits the actions of FSH and forskolin in meiotic maturation of pig oocytes via different
signaling pathways. Journal of Molecular Endocrinology 34:459-472.
20. Jiang MX, Lei ZL, Ouyang YC, Zhu ZY, Zheng YL, Sun QY, Chen DY (2005) Full-term development of
mouse eggs transplanted with male pronuclei derived from round spermatids: The effect of synchronization
between male and female pronucleus on embryonic development. Molecular Reproduction and
Development 71:439-443.
21. Kong FY, Sun QY, Chen DY (2005) Transplantation of male pronucleus derived from in vitro fertilization
of enucleated oocyte into parthenogenetically activated oocytes results in live offspring in mouse. Zygote
13:35-38.
22. Tan X, Peng A, Wang YC, Wang Y, Sun QY (2005) Participation of the ubiquitin proteasome pathway in rat
oocyte activation. Zygote 13:87-95.
23. Tan X, Wang YC, Sun QY, Peng A, Chen DY, Tang YZ (2005) Effect of MAP kinase pathway and other
factors on meiosis of Urechis unicinctus Eggs. Molecular Reproduction and Development 71:67-76.
24. Zhang LS, Yao LJ, Jiang MX, Lei ZL, Sun QY, Chen DY (2005)Transplantation of somatic nuclei into
oocyte cytoplasm reveals that the chromosome properties determine the chromosome separation fate in
rabbit. Zygote 13(:109-14.
25. Jiang Y, Chen T, Nan CL, Ouyang YC, Sun QY, Chen DY (2005) In vitro culture and mtDNA fate of
ibex-rabbit nuclear transfer embryos. Zygote 13:233-240.
26. Jiang MX, Zheng YL, Liu SZ, Yang CX, Zhang LS, Ouyang YC, Sun QY, Chen DY (2005) Effects of
oocyte collection time and injection position on pronucleus formation and blastocyst development in round
spermatid injection in mouse. Zygote 13:249-253.
Publications in 2004
1.
Chen T, Zhang YL, Jiang Y, Liu SZ, Schatten H, Chen DY, Sun QY* (2004) DNA methylation pattern in
normal and cloned rabbit embryos. FEBS Letters 578: 69-72.
2.
Huo LJ, Fan HY, Liang CG,Yu LZ, Zhong ZS,Chen Dy, Sun QY* (2004) Regulation of
ubiquitin-proteasome pathway on pig oocyte meiotic maturation and fertilization. Biology of Reproduction
71:835-862.
3.
Yao LJ, Zhong ZS, Chen DY, Schatten H, Sun QY* (2004) Auroa-A is a critical regulator of microtubule
organization and nuclear activity in pig oocytes, fertilized eggs and early embryos. Biology of
Reproduction 70:1392-1399.
- 19 -
4.
Fan HY, Huo LJ, Chen DY, Schatten H, Sun QY* (2004) Protein kinase C and mitogen-actuivated protein
kinase cascade in mouse cumulus cells:crosstalk and effect on meiotic resumption of oocytes. Biology of
Reproduction 70:1178-1187.
5.
Huo LJ, Fan HY, Zhong ZS, Chen DY, Schatten H, Sun QY* (2004) Ubiquitin-proteasome pathway
modulates mouse oocyte meiotic maturation and fertilization via regulation of MAPK cascade and cyclin
B1 degradation. Mechanisms of Development 121:1275-1287.
6.
Sun QY, Fuchimato D, Nagai T (2004) Regulatory roles of ubiquitin-proteasome pathway in pig oocyte
meiotic maturation and fertilization. Theriogenology 62：245-255.
7.
Zhang LS, Jiang MX, Lei ZL, Li RC, Sang D, Sun QY, Chen DY (2004) Development of goat embryos
reconstituted with somatic cells: the effect of cell-cycle coordination between transferred nucleus and
recipient oocytes. Journal of Reproduction and Development 50:661-616.
8.
Jiang MX, Yang CX, Zhang LS, Zheng YL, Liu SZ, Sun QY, Chen DY (2004) The effects of chemical
enucleation combined with whole cell intracytoplasmic injection on panda-rabbit interspecies nuclear
transfer. Zygote 12:315-320.
9.
Zhang LS, Jiang MX, Lei ZL, Li RC, Sang D, Sun QY，Chen DY (2004) Development of goat embryos
reconstituted with somatic cells: the effect of cell-cycle coordination between transferred nucleus and
recipient oocytes. Journal of Reproduction and Development 50:661-666.
10. Han ZM, Chen DY, Li JS, Sun QY, Wan QH, Kou ZH, Rao G, Lei L, Liu ZH, Fang SG (2004)
Mitochondrial DNA heteroplasmy in calves cloned by using adult somatic cell. Molecular Reproduction
and Development 67:207-214.
11. Zhang LS，Zhang KY, Yao LJ, Liu SZ,Yang CX, Zhong ZS, Zheng YL, Sun QY, Chen DY (2004)
Somatice cell nuclear remodeling in Rassir oocyte cytoplasm. Zygote 12：179-184.
12. Liu SZ, Zhou ZM, Chen T, Zhang YL, Wen DC, Kou ZH, Li ZD, Sun QY, Chen DY (2004) Blastocysts
produced by nuclear transfer between chicken blastodermal cells and rabbit oocytes. Molecular
Reproduction and Development 69:296-302.
13. Zhang D, Ma W, Li YH, Hou Y, Li SW, Meng XQ, Sun XF, Sun QY, Wang WH (2004) Intraoocyte
Localization of MAD2 and its relationship with kinetochores, microtubules, and chromosomes in rat
oocytes during meiosis. Biology of Reproduction 71:740-748.
14. Zheng YL, Jang MX, Zhang YL, Sun QY, Chen DY (2004) Effects of oocyte age, cumulus cells and
injection methods on in vitro development of intracytoplasmic sperm injection rabbit embryos. Zygote
12:75-80.
15. Li M, Li YH, Hou Y, Sun XF, Sun QY, Wang WH (2004) Isolation and culture of pluripotent cells from in
vitro produced porcine embryos. Zygote 12:43-48.
- 20 -
16. Meng XQ, Fan HY, Zhong ZS, Zhang G, Li YL, Chen DY, Sun QY* (2004) Localization of -tubulin in
mouse eggs during meiotic maturation, fertilization and early embryonic development. Journal of
Reproduction and Development 50:97-105.
17. Yao LJ, zhang LS, Kou ZH, Chen DY, Sun QY* (2004) Translocation of -tubulin during porcine oocyte
maturation and activation. Prog. Biochem Biophys 31:339-344.
18. Li M, Hou Y, Sun XF, Sun QY, Wang WH (2004) Improved isolation and culture of ES cells from Chinese
miniature pigs. Journal of Reproduction and Development 50:237-244.
19. Fan HY，Huo LJ，Sun QY* (2004) Methodology for detection of spindle-associated proteins by confocal
microscopy in mammalian oocytes. Prog. Biochem Biophys 31: 54-58
20. Quan HM, Meng XQ, Hou Y, Sun QY* (2004) Sperm penetration of immature and maturing oocytes does
not affect phosphorylation of mitogen-activated protein kinase in pigs. Reproduction Fertility and
Development 15:383-387.
21. Li YH, Hou Yi, Ma W, Yuan JX, Zhang D, Sun QY, Wang WH (2004) Localization of CD9 in pig oocytes
and its effects on sperm-egg interaction. Reproduction 127:151-157.
22. Yang CX, Kou ZH, Wang K, Jiang Y, Mao WW, Sun QY, Sheng HZ, Chen DY. (2004) Quantitative
analysis of mitochondiral DNAs in macaque embryos reprogrammed by rabbit oocytes. Reproduction
127:201-205.
Publications in 2003
1.
Fan HY Huo LJ, Meng XQ, Zhong ZS, Hou Y, Chen DY, Sun QY* (2003)Involvement of
calcium/calmodulin-dependent protein kinase II (CaMKII) in meiotic maturation and activation of pig
oocytes. Biology of Reproduction 69:1552-1564.
2.
Fan HY, Tong C, Lian L, Li SW, Gao WX, Cheng Y, Chen DY, Schatten H, Sun QY* (2003)
Characterization of ribosomal protein kinase p90rsk during meiotic maturation and fertilization in pig
oocytes: mitogen-activated protein kinase-associated activation and localization. Biology of Reproduction
68:968-977.
3.
Fan HY, Tong C, Teng CB, Lian L, Li SW, Yang ZM, Chen DY, Schatten H, Sun QY* (2003)
Characterization of polo-like kinase-1 in rat oocytes and early embryos implies its functional roles in the
regulation of meiotic maturation, fertilization and cleavage. Molecular Reproduction and Development
65:318-329.
4.
Zhu ZY, Chen DY, Li JS, Lian L, Lei L, Han ZM, Sun QY (2003) Rotation of MII spindle is controlled by
microfilaments in mouse oocytes. Biology of Reproduction 68:934-937.
5.
Quan HM, Fen HY, Meng XQ, Huo LJ, Chen DY, Scahtten H, Sun QY* (2003) Effect of protein kinase C
activation on mouse oocyte meiotic maturation, fertilization and early embryo development. Zygote
- 21 -
11:329-337.
6.
Liu RH, Sun QY, Li YH, Jiao LH, Wang WH (2003) Maturation of porcine oocytes after cooling at the
germinal vesicle stage. Zygote 11:299-305.
7.
Yao LJ, Fan HY, Tong C, Chen DY, Schatten H, and Sun QY* (2003) Polo-like Kinase-1 in Porcine Oocyte
Meiotic Maturation, Fertilization and Early Embryonic Mitosis. Cellular and Molecular Biology 49:
399-405.
8.
Wen DC, Yang CX, Cheng Y, Li JS, Liu ZH, Sun QY, Zhang JX, Lei L, Kou ZH, Chen DY (2003)
Comparision of developmental capacity for intra- and interspecies cloned cat (Felis catus) embryos.
Molecular Reproduction and Development 66: 38-45.
9.
Wa W,Hou Y, Sun QY, Sun XF, Wang WH (2003) Localization of centrosome proteins and their association
with chromosomes and microtubules during meiotic maturation of pig oocytes. Reproduction 126:731-738.
10. Yang CX, Han ZM，Wen DC, Sun QY, Zhang KY, Zhang LS , Wu YQ, Kou ZH, Sheng HZ, Chen DY
(2003) In vitro development and mitochondria fate of macaque-rabbit cloned embryos. Molecular
Reproduction and Development 65:396-401.
11. Tong C, Fan HY, Li SW, Chen DY, Song XF, Schatten H, Sun QY* (2003) Effect of MEK inhibitor U0126
on meiotic progression in mouse oocytes: microtubule organization, asymmetric division and metaphase II
arrest. Cell Research 13:375-383.
12. Han ZM, Chen DY, Li JS, Sun QY, Wang PY, Du J, Zhang HM (2003) Flow cytometric cell-cycle analysis
of cultured fibroblast cells from the giant panda, Ailuropoda melanoleuca L. Cell Biology International
27:349-353.
13. Chen DY, Li JS, Han ZM, Lai L, Liu ZH, Kou ZH, Ma SY, Du QK, Sun QY (2003) somatic cell bovine
cloning: Effect of donor cell and recipients. Chinese Science Bulletin 48:549-554.
14. Cheng Y， Fan HY，Wen DC， Tong C， Zhu ZY， Lei L， Sun QY， Chen DY (2003) Asynchronous
cytoplast and karyoplast transplantation in mouse oocytes. Molecular Reproduction and Development
65:278-282.
15. Liu RU, Sun QY, Li YH, Jiao LH, Wang WH (2003) Effects of cooling on oocyte maturation, meiotic
spindle structure and chromosome alignment in in vitro maturing porcine oocytes. Molecular Reproduction
and Development 65:212-218.
16. Cheng Y, Han ZM, Sun QY, Chen DY (2003) Development of mouse embryos derived from oocytes
reconstructed by metaphase I spindle transfer. Zygote 11:53-59.
Publications in 2002
1.
Sun QY, Wu GM, Lai L, Bonk A, Cabot R, Park K, Day BN,Prather RS, Schatten H. (2002) Regulation of
mitogen-activated protein kinase phosphorylation, chromatin behavior, microtubule organization, and cell
- 22 -
cycle progression by protein phosphatases during pig oocyte maturation and fertilization in vitro. Biology
of Reproduction 66:580-588.
2.
Lu Q, Smith G, Chen DY, Han ZM, Sun QY*(2002) Activation of protein kinse C induces MAP kinase
dephosphorylation and pronucleus formation in rat oocytes. Biology of Reproduction 67:64-69.
3.
Fan HY, Tong C, Lian L, Chen DY, Schatten H, Sun QY* (2002) Translocation of classical protein kinase
C (cPKC) isoforms in porcine oocytes: implications of PKC involvement in the regulation of nuclear
activity and cortical granule exocytosis. Experimental Cell Research 277:183-191.
4.
Tong C, Fan HY, Lian L, Chen DY, Schatten H, Sun QY* (2002) Polo-like kinase is a pivotal regulator of
microtubule organization during mouse oocyte maturation, fertilization and early embryonic mitosis.
Biology of Reproduction 67:546-554.
5.
Fan HY, Li MY, Tong C, Chen DY, Xiao GL, Sun QY* (2002) Inhibitory effects of cAMP and protein
kinase C on meiotic maturation and MAP kinase phosphorylation in porcine oocytes. Molecular
Reproduction and Development 63:480-487.
6.
Yu HQ, Chen DY, Shorgan B, Sun QY* (2002) Phosphorylation of MAP kinase and p90rsk and its
regulation during in vitro maturation of cumulus-enclosed rabbit oocytes. Zygote 10:311-316.
7.
Fan HY, Tong C, Li SW, Chen DY, Sun QY* (2002) Microtubule organization during in vitro development
of rat oocytes. Prog. Biochem Biophys 29:708-713.
8.
Cheong HC, Park KW, Im GS, Lai L, Sun QY, Day BN, Perather RS (2002) Effect of elevated Ca2+
concentration in fusion/activation medium on the fusion and development of porcine fetal fibroblast
nuclear transfer embryos. Molecular Reproduction and Development 61:488-492.
9.
Li JS, Chen DY, Han ZM, Zhu ZY, Wen DC, Sun QY, Liu ZH, Wang MK, Lian L, Du J, Wang PY, Zhang
HM (2002) Serial nuclear transfer improves the development of interspecies constructed giant panda
embryos. Chinese Science Bulletin 47:467-469.
10. Li MY, Fan Hy, Tong C, Chen DY, Xia GL, Sun QY* (2002) MAPK regulates cell cycle progression in pig
oocytes and fertilized eggs. Chinese Science Bulletin 47:843-847.
11. Park, KW, Lai L, Cheong HT, Cabot R, Sun QY, Wu G, Rucker EB, Durtschi D, Bonk A, Samuel M, Rieke
A, Day BN, Murphy CN, Carter DB, Prather RS (2002) Mosaic gene expression in nuclear transfer-derived
embryos and the production of cloned transgenic pigs from ear-derived fibroblasts. Biology of
Reproduction. 66: 1551-1559.
12. Wu GM, Sun QY, Mao J, Lai L, McCauley TC, Park KW, Prather RS, Didion BA, Day BN (2002) High
developmental competence of pig oocytes after meiotic inhibition with a specific M-phase promoting factor
kinase inhibitor, butyrolactone I. Biology of Reproduction 67:170-177.
13. Chen DY, Wen DC, Zhang YP, Sun QY, Han ZM, Shi P, Jingong XY, Chen YC, Wang PY, Zhang HM
- 23 -
(2002) Interspecies implantation and mitochondria fate of panda-rabbit cloned embryos. Biology of
Reproduction 67:634-642.
Publications in 2001
1.
Sun QY, Lai L, Park KW, Kuhholzer B, Prather RS and Schatten H (2001) Dynamic events are differently
mediated by microfilaments, microtubules, and mitogen-activated protein kinase during porcine oocyte
maturation and fertilization in vitro. Biology of Reproduction 64: 871-889.
2.
Lu Q, Smith GD, Chen DY, Yang Z, Han ZM, Schatten H, Sun QY* (2001) Phosphorylation of
mitogen-activated protein kinase is regulated by protein kinase C, cyclic 3’,5’-adenosine monophosphate,
and protein phosphatase modulators during meiotic resumption in rat oocytes. Biology of Reproduction
64:1444-1450.
3.
Sun QY, Lai L, Bonk A, Prather RS and Schatten H (2001) Cytoplasmic changes in relation to nuclear
maturation and early embryo developmental potential of porcine oocytes: effects of gonadotropins,
cumulus cells, folliclular size and protein synthesis inhibition. Molecular Reproduction and Development
59: 131-137.
4.
Sun QY, Wu GM, Lai LX, Park KW, Day BN, Prather RS and Schatten H (2001) Translocation of active
mitochondria during pig oocyte maturation, fertilization and early embryos development in vitro.
Reproduction 122:155-163.
5.
Sun QY, Lai LX, Wu GM, Park KW, Day BN Prather RS and Schatten H (2001) Microtubule assembly
after treatment of pig oocytes with taxol: correlation with chromosomes, -tubulin and MAP kinase.
Molecular Reproduction and Development 60:481-490.
6.
Wang MK, Chen DY, Liu JL, Li GP and Sun QY (2001) In vitro fertilization of mouse oocytes
reconstructed by transfer of metaphase II chromosomes results in live birth. Zygote 9: 9-14.
7.
Tan X, Chen DY, Yang Z, Wang YC, Schatten H and Sun QY*(2001) Phosphorylation of p90rsk during
meiotic maturation and pathenogenic activation of rat oocytes: correlation with MAP kinase. Zygote
9:269-276.
8.
Li GP, Chen DY, Lian L, Sun QY, Wang MK, Song XF, Meng L and Schatten H (2001) Mouse-rabbit
germinal vesicle transfer reveals that factors regulating oocyte meiotic progression are not species-specific
in mammals. Journal of Experimental Zoology 289: 322-329.
9.
Li GP, Chen DY, Lian L, Sun QY, Wang MK, Lui JL, Li JS and Han ZM (2001) Viable rabbits derived
from reconstructed oocytes by germinal vesicle transfer after intracytoplasmic sperm injection. Molecular
Reproduction and Development 58: 180-185.
10. Park K, Kuhholzer B, Lai L, Machaty Z, Sun QY, Day BN, Pather RS (2001) Development and expression
of the green fluorescent protein in porcine embryos derived fro nucleat transfer of transgenic
- 24 -
granulose-derived cells. Animal Reproduction Science 68: 111-120.
11. Gobert GN, Hueser CH, Curran EM, Sun QY and Schatten H (2001) Immunolocalization of NuMA and
phosphorylated proteins during the cell cycle in human breast and prostate cancer cells as analysed by
immunofluorescence and postembedding immunodetection microscopy. Histochemistry and Cell Biology
115：381-395.
12. Lai LX, Tao T, Machaty Z, Kuhholzer B, Sun QY, Park KW Day BN, Prather RS(2001) Feasibility of
producing porcine nuclear transfer by using G2/M-stage fetal fibroblasts as donors. Biology of
Reproduction 65:1558-1564.
13. Liu JL, Wang MK, Sun QY, Zhang XR, Jiang Lk, Chen DY (2001) Refrigeration of donor cells in
preparation for bovine somatic nuclear transfer. Reproduction 122:801-808.
14. Lai L, Sun QY, Wu GM, Murphy CN, Kuhholzer B, Park KW, Day BN, Prather RS (2001) Development of
porcine embryos and offspring after intracytoplasmic sperm injection with liposome transfected or
non-transfected sperm into in vitro matured oocytes. Zygote 9:339-346.
15. Park KW, Lai L, Cheong K, Im GS, Sun QY, Day BN, Prather RS (2001) Developmental potential of
procine nuclear transfer embryos derived from transgenic fetal bibroblasts infected with the gene for the
green fluorescent protein: comparision of different fusion/activation conditions. Biology of Reproduction
65:1681-1685.
16. Han ZM, Chen DY, Li JS, Sun QY, Wang PY, Huang Y, Du J (2001) The culture of fibroblass from
diaphyram of giant panda. In Vitro Animal 37: 37:644-645.
Publications in 2000
1.
Sun QY, Lai LX, Prather RS and Schatten H (2000) Antioxidants stimulate meiosis resumption, but inhibit
MAP kinase phosphorylation and farther cell cycle progression in porcine oocytes. Reproduction, Fertility
and Development 12:383-389.
2.
Liu JL, Wang MK, Sun QY, Xu Z and Chen DY (2000) Effect of teleophase enucleation on bovine somatic
nuclear transfer. Theriogenology 54: 989-998.
3.
Luria A, Tennenbaum T, Sun QY, Rubinstein S and Breitbart H (2000) Differential localization of
conventional protein kinase C isoforms during mouse oocyte development. Biology of Reproduction
62:1564-1570.
4.
Li GP, Tan JH, Sun QY, Meng QG, Yue KZ, Sun XS, Li ZY, Wang HB, Xu LB (2000) Cloned piglets born
after nuclear transplantation of embryonic blastomeres into porcine oocytes matured in vitro. Cloning 2:
45-52.
Publications before 2000
1.
Sun QY, Rubinstein S and Breitbart H (1999) MAP kinase activity is downregulated by phorbol ester
- 25 -
during mouse oocyte maturation and egg fertilization. Molecular Reproduction and Development 52:
380-386.
2.
Sun QY, Lu Q, Breitbart H and Chen DY (1999) cAMP inhibits MAP kinase activation and reinitiation of
meiosis, but exerts no effects after germinal vesicle breakdown (GVBD) in mouse oocytes. Reproduction,
Fertility and Development 11: 81-86.
3.
Sun QY, Lax Y, Rubinstein S and Breitbart H (1999) Mitogen-activated protein kinase and cell cycle
progression during mouse egg activation induced by various stimuli. Z Naturforsch[C] 54:285-294.
4.
Sun QY, Rubinstein S and Breitbart H (1999) MAP kinase in human eggs. Zygote 7:181-185.
5.
Liu JL, Chen YC, Sun QY, Song XF, Chen DY (1999) Culture of skeletal muscle cells from giant panda. In
Vitro Cell Dev Biol Anim 35(10):553-4.
6.
Zhuang DZ, Song XF, Hu GJ, Sun QY, Chen DY (1999) Sperm antigen MSH27 participates in sperm-egg
membrane fusion. Chinese Science Bulletin 44:1483-1488.
7.
Liu JL, Wang MK, Lian L, Gao SR, Sun QY, Song XF, Zhang DM, Li Y, Xu Z, Chen DY (1999) Nuclear
transfer using non-quiescent adult fibroblasts from a bovine ear. Chinese Science Bulletin 44: 1971-1974.
8.
Ding B, Shi P, Xianyu J, Zhang YP, Sun QY, Han ZM, Chen DY (1999) Microsatellite DNA analysis
proves that nucleus of interspecies reconstructed blastocyst comes from giant panda donor cells. Chinese
Science Bulletin 45:1883-1885.
9.
Lu Q, Sun QY, Duan CW, Brietbart H and Chen DY (1999) Expression and phosphorylation of
mitogen-activated protein kinase during mouse spermatogenesis and epididymal maturation. Archives of
Andrology 43:55-66.
10. Chen DY, Sun QY, Liu JL, Li GP, Lian L, Wang MK, Han ZM, Song XF, Li JS, Sun Q, Zhang YP, Ding B
and Chen YC (1999) The giant panda (Ailuropoda melanoleuca) somatic cell nucleus can dedifferentiate in
rabbit ooplasm and surpport early development of reconstructed egg. Science in China (Series C)
42:346-353.
11. Sun QY, Luria A, Rubinstein S and Breitbart H (1998) Protein kinase inhibitors activate mouse
eggs via
inactivation of MAP kinase. Zygote 6: 277-284.
12. Sun QY*, Wang WH, Hosoe M, Taniguchi T, Chen DY and Shioya Y (1997) Activation of protein kinase C
induces cortical granule exocytosis in a Ca2+-independent manner, but not the resumption of cell cycle in
porcine eggs. Development, Growth & Differentiation 39:523-529.
13. Sun QY, Liu H and Chen DY (1997) Calcium-independent, egg-age-dependent parthenogenic activation of
mouse eggs by staurosporine. Journal of Reproduction and Development 43:189-197.
14. Wang WH, Sun QY, Hosoe M, Shioya Y and Day BN (1997) Quantified analysis of cortical granule
distribution and exocytosis of porcine oocyte meiotic maturation and activation. Biology of Reproduction
- 26 -
56: 1376-1382.
15. Wang WH, Sun QY, Hosoe M and Shioya Y (1997) Calcium and meiotic spindle-independent activation of
porcine oocytes by inhibition of staurosporine-sensitive protein kinase. Zygote 5: 75-82.
16. Liu L, Sun QY, Duan CW, Liu H Song XF, Qian JF and Chen DY (1997) Subzonal fertilization of mouse
round spermatids. Science in China (Series C) 40: 152-158.
17. Chen DY, Du M, Zou X, Song XF, Sun QY, Duan CW, Liu H (1997) Mechanism of sperm-egg recognitioin
during subzonal (perivitelline space) insemination. Chinese Science Bulletin 41:1559-1663.
18. Sun QY, Liu H, Li XB, Song XF, Yu JQ, Li GH and Chen DY (1996) The role of Ca2+ and protein kinase
C in the acrosome reaction of giant panda sperm. Theriogenology 46:359-367.
19. Chen DY, Song XF, Duan CW, Li MW, Sun QY, Liu H, Zhang A, Ye ZY (1996)Applying bases for “double
control” artificial breeding of giant panda in captivity. Chinese Science Bulletin 42:775-779.
20. Li MW, Jiao R, Sun QY, Hu GJ, Duan CW, Liu H, Song XF, Chen DY (1996) Signal transduction pathways
in guinea pig sperm. Science in China (Series C) 41:363-368.
21. Feng HL, Liu JM, Wen XH, Sun QY, Qin PC (1994) Follicular oocyte maturation and sperm penetration in
vitro in the silver fox. Animal Reproduction Science 36: 163-170.
22. Feng HL, Yang QZ, Sun QY, Qin PC (1994) Development of early bovine embryos in different culture
systems. Veterinary Record 135:304-306.
(A total of 54 papers published in Chinese journals are not listed)
Book and book chapters:
1.
Chen DY, Sun QY, Li GP (2002) Fertilization Biology, Science Press, Beijing
2.
Yang ZM, Sun QY, Xia GL (2005) Reproductive Biology, Science Press, Beijing
3.
Sun QY (2003) Molecular Events of Development (In LI YL eds：Mammalian Developmental Biology,
Shandong Science Press
4.
Sun QY and Fan HY (2004) MAP kinase activity during fertilization. In:Schatten H (eds), Methods in
Molecular Biology: Germ Cell Protocols, pp293-304,Humana Press, USA
5.
Fan HY and Sun QY (2004) In vitro fertilization of pig oocytes . In: Schatten H (eds), Methods in
Molecular Biology: Germ Cell Protocols, pp227-233,Humana Press, USA.
6.
Sun QY, Schatten H (2006) Centrosomal inheritance after fertilization and nuclear transfer. In P Sutovasky
(eds), Somatic Cell Nuclear Transfer, pp58-71,Lands Bioscience, USA
7.
Sun QY, Chen DY (2006) Manipulating the Mouse Embryo: A Laboratory Manual (Third edition), China
Chemical Industry Press, Beijing. (English to Chinese Translation).
8.
Chen DY, Sun QY, Jiang Y (2005) Cloning: Xerox machine in life sciences. Shao-Nian-Er-Tong Publishing
- 27 -
House, Shanghai.
9.
Wang WH and Sun QY (2007) Reproduction Revolution: New Era of Test-Tube Baby. Science Press,
Beijing.
- 28 -