Preliminary Program
The Growth Hormone/Prolactin Family in Biology and Disease
July 12-17, 2015
Steamboat Springs Grand Resort Hotel
Steamboat Springs, Colorado
Co-organizers:
Christin CARTER-SU, PhD
University of Michigan
Ann Arbor, MI
Linda SCHULER, PhD
University of Wisconsin
Madison, WI
Sunday
July 12, 2015
4:00 PM – 9:00 PM
Conference Registration
5:00 PM – 6:00 PM
FASEB SRC Welcome Reception
6:00 PM – 7:00 PM
Dinner
7:15 PM – 8:30 PM
Chair: Christin CARTER-SU, PhD (University of Michigan, USA)
Robert Kennedy, PhD (University of Michigan, USA)
“Novel nanoscale techniques to measure hormones, neurotransmitters, metabolites
and signal transduction in isolated cells and living animals”
Monday
July 13, 2015
7:30 AM – 9:00 AM
Breakfast
Session 1:
9:00 AM – 12:15 PM
GH/PRL use, abuse and function in adults
Chair: Christian STRASBURGER, MD (Charitè Universitätsmedizin,
Germany)
9:00 AM – 9:15 AM
Welcome from FASEB
9:15 AM – 9:45 AM
Larry BOWERS, PhD (Chief Scientific Officer, US Anti-Doping Agency)
“Use of performance enhancing drugs in sports: Reality and challenges”
9:45 AM – 10:15 AM
Karen K. MILLER, MD (Harvard Medical School, USA)
“The GH Axis in Adults Throughout the Weight Spectrum”
10:15 AM – 10:30 AM
Short Talk Selected From Submitted Abstracts
10:30 AM – 11:00 AM
Group photo & FASEB Sponsored Coffee Break
11:00 AM – 11:15 AM
Short Talk Selected From Submitted Abstracts
11:15 AM – 11:45 AM
Jesus DEVESA, MD, PhD (University of Santiago de Compostela, Spain)
“GH administration in acquired neural injuries”
11:45 AM – 12:15 PM
Ingrid STRUMAN, (University of Liege, Belgium)
“PRL/GH fragments in thrombolysis”
12:15 PM – 1:15 PM
Lunch
Free Afternoon
4:00 PM – 6:00 PM
Poster Session 1
6:00 PM – 7:00 PM
Dinner
Session 2:
7:00 PM – 9:45 PM
GH/PRL synthesis and secretion: unique problems and special insights
Chair: Christopher ORMANDY, PhD (Garvin Institute, Australia)
7:00 PM – 7:30 PM
Arthur GUTIERREZ-HARTMANN, MD (University of Colorado, USA)
“Distinct roles of the Ras/MAPK and PI3K pathways in differentiation vs
proliferation and tumorigenesis in GH4 rat somato-lactotrope tumor cells”
7:30 PM – 8:00 PM
Stephen LIEBHABER, MD (University of Pennsylvania, USA)
“Chromatin structure and hGH gene expression”
8:00 PM – 8:15 PM
Short Talk Selected From Submitted Abstracts
8:15 PM – 8:30 PM
Break
8:30 PM – 8:45 PM
Short Talk Selected From Submitted Abstracts
8:45 PM – 9:15 PM
Frederik STEYN, PhD (University of Queensland, Australia)
“Regulation of pulsatile GH secretion”
9:15 PM – 9:45 PM
Lydia ARBOGAST, PhD (Southern Illinois University, USA)
“Prolactin and progesterone regulation of hypothalamic dopaminergic neurons”
Tuesday,
July 14, 2015
7:30 AM – 9:00 AM
Breakfast
Session 3
9:00 AM – 12:15 AM
Beyond growth and lactation: Non-traditional actions of GH/PRL
Chair: Nira BEN-JONATHAN, PhD (University of Cincinnati, USA)
9:00 AM – 9:30 AM
Carmen CLAPP, PhD (National University of Mexico, Mexico)
“PRL protects against joint destruction and inflammation”
9:30 AM – 10:00 AM
Mark H. VICKERS, PhD (The University of Auckland, New Zealand)
“GH and developmental programming of disease”
10:00 AM – 10:15 AM
Short Talk Selected From Submitted Abstracts
10:15 AM – 10:45 AM
FASEB Sponsored Coffee Break and Group Photo
10:45 AM – 11:15 AM
Andreas FRIEDL, MD (University of Wisconsin, USA)
“PRL and angiogenesis”
11:15 AM – 12:00 PM
David GRATTAN, PhD (University of Orago, New Zealand)
Tracking and modulating PRL action in the central nervous system”
12:00 PM – 12:15 PM
Short Talk Selected From Submitted Abstracts
12:15 PM – 1:15 PM
Lunch
Free Afternoon
4:00 PM – 6:00 PM
Poster Session 2
6:00 PM – 7:00 PM
Dinner
Session 4
7:00 PM – 9:45 PM
Initiation and modulation of GH/PRL signaling pathways
Chair: Ameae WALKER, PhD (University of California Riverside, USA)
7:00 PM – 7:30 PM
Michael WATERS, PhD (University of Queensland, Australia)
“Activation of the GH receptor and its consequences”
7:30 PM – 8:00 PM
Birthe KRAGELUND, PhD (University of Copenhagen, Denmark)
“Activation of the PRL receptor”
8:00 PM – 8:15 PM
Short Talk Selected From Submitted Abstracts
8:15 PM – 8:30 PM
Break
8:30 PM – 8:45 PM
Short Talk Selected From Submitted Abstracts
8:45 PM – 9:15 PM
Maria DIAKONOVA, PhD (University of Toledo, USA)
“Novel centrosomal-dependent mechanism of JAK2 regulation in PRL signaling”
9:15 PM – 9:45 PM
Stuart J. FRANK, MD (University of Alabama at Birmingham, USA)
“GH receptor – PRL receptor interactions and signaling”
Wednesday,
July 15, 2015
7:30 AM – 9:00 AM
Breakfast
Session 5
9:00 AM – 12:15 PM
New insights into GH/PRL physiological regulatory networks
Chair: Peter LOBIE, PhD (National University of Singapore, Singapore)
9:00 AM - 9:30 AM
Ethan WEISS, MD (University of California – San Francisco, USA)
“Physiological consequences of tissue specific deletion of Jak2”
9:30 AM – 10:00 AM
Rhonda KINEMAN, PhD (University of Illinois – Chicago, USA)
“Sexual Dimorphic Impact of Adult-Onset Hepatic GH Resistance on Glucose
and Lipid Metabolism”
10:00 AM – 10:15 AM
Short Talk Selected From Submitted Abstracts
10:15 AM – 10:45 AM
FASEB Sponsored Coffee Break
10:45 AM – 11:15 AM
Yutaka TAKAHASHI, PhD (Kobe University, Japan)
“GH resistance under fasting conditions: the role of SIRT1 in endocrine adaptation”
11:15 AM – 12:00 PM
Armen AKOPIAN, PhD (University of Texas Health Science Center at
San Antonio, USA)
“Role of PRL in regulation of the pain pathway”
12:00 PM – 12:15 PM
Short Talk Selected From Submitted Abstracts
12:15 PM – 1:15 PM
Lunch
1:15 PM – 2:15 PM
Meet the Expert
Free Afternoon
4:00 PM – 6:00 PM
Poster Session 3
6:00 PM – 7:00 PM
Dinner
Session 6
7:00 PM – 9:45 PM
Expanding insights into the role of GH/IGF-1/PRL in cancer
initiation and progression
Chair: Marja NEVALAINEN, MD, PhD (Jefferson Kimmel Cancer
Center, USA)
7:00 PM – 7:30 PM
Vincent GOFFIN, PhD (Inserm and University Paris Descartes, France)
“Use of probasin-PRL transgenic mice as a research, discovery and
preclinical tool for prostate tumors”
7:30 PM – 8:00 PM
Szeman Ruby CHAN, PhD (Washington University, USA)
“Stat1-Socs1 regulation of ERα+ mammary tumorigenesis”
8:00 PM – 8:15 PM
Short Talk Selected From Submitted Abstracts
8:15 PM – 8:30 PM
Break
8:30 PM – 8:45 PM
Short Talk Selected From Submitted Abstracts
8:45 PM – 9:15 PM
Richard MORIGGL, PhD (Ludwig Boltzmann Institute for Cancer research, Austria)
“GH-induced Jak2-Stat5 signaling and the influence by the glucocorticoid
receptor pathway in liver cancer and metabolic diseases”
9:15 PM – 9:45 PM
Valentine MACAULAY, MD, PhD (University of Oxford, United Kingdom)
“IGF signalling in tumour biology”
Thursday,
July 16, 2015
7:30 AM – 9:00 AM
Breakfast
Session 7
9:00 AM – 12:15 PM
Genomic and epigenetic perspectives on GH/PRL function
Chair: Kay-Uwe WAGNER, PhD (University of Nebraska Medical Center,
USA)
9:00 AM – 9:30 AM
Willis Li, PhD (University of California – San Diego, USA)
“Jak/Stat regulation of cellular epigenetic states”
9:30 AM – 10:00 AM
David FRANK, MD, PhD (Dana Farber Cancer Institute, USA)
“Stats as components of transcriptional networks”
10:00 AM – 10:15 AM
Short Talk Selected From Submitted Abstracts
10:15 AM – 10:45 AM
FASEB Sponsored Coffee Break
10:45 AM – 11:00 AM
Short Talk Selected From Submitted Abstracts
11:00 AM – 11:30 AM
Diane ROBINS, PhD (University of Michigan, USA)
“Dynamic interplay between Stat5b and a KRAB-ZFP repressor”
11:30 AM – 12:00 PM
David WAXMAN, PhD (Boston University, USA)
“Hepatic Actions of GH: microRNAs, lincRNAs and chromatin states”
12:00 PM – 12:45 PM
Business Meeting
12:45 PM – 1:45 PM
Lunch
Free Afternoon
1:00 PM – 6:00 PM
Optional Organized Group Activity
4:00 PM – 6:00 PM
Poster Session 4
6:00 PM – 7:00 PM
Dinner
Session 8:
7:00 PM – 9:45 PM
Targeting GH-PRL signals for therapeutic benefit
Chair: John KOPCHICK, PhD (Ohio University, USA)
7:00 PM – 7:30 PM
James TURKSON, PhD (University of Hawaii, USA)
“Therapeutic modulators of Jak/Stat signaling for human diseases”
7:30 PM – 8:00 PM
Jens Sandhal CHRISTIANSEN, MD, DMSc (Aarhus University, Denmark)
“Diagnosis and treatment of GH deficiency in adults”
8:00 PM – 8:15 PM
Short Talk Selected From Submitted Abstracts
8:15 PM – 8:30 PM
Break
8:30 PM – 8:45 PM
Short Talk Selected From Submitted Abstracts
8:45 PM – 9:15 PM
George BRIGHT, MD (Versartis, USA) (invited)
“GH and IGF-I therapy in humans: 90 years and counting”
9:15 PM – 9:45 PM
Charles V. CLEVENGER, MD, PhD (Virginia Commonwealth
University, USA)
“PRL-related targets in breast cancer”
9:45 PM -
Christin CARTER-SU and Linda SCHULER: concluding remarks
10:00 PM
Social gathering
Friday,
July 17, 2015
7:30 AM – 8:30 AM
Breakfast
8:30 AM
Departures
Boxed Lunches Available
END OF CONFERENCE
For additional information contact:
FASEB Summer Research Conferences
9650 Rockville Pike
Bethesda, MD 20814
@faseb.org
www.faseb.org/src