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February 2016
Volume 136, Issue 2
About the Cover
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2014 Impact Factor: 7.216*
#1 Journal in Dermatology
*2014 Journal Citation Reports® Science Edition (Thomson Reuters, 2015)
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SkinPods
Video
3 February 2016: Matthew Rodeheffer, PhD of Yale University discusses his talk,"
Understanding how we get fat: Dietary regulation of adipocyte precursors," presented at the 2015
Montagna Symposium on the Biology of Skin."
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JID Author Corner
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Elsewhere in Dermatology
From the Journal of the American Academy of Dermatology:
Cutaneous adverse events (AEs) of anti-programmed cell death (PD)-1 therapy in patients with
metastatic melanoma: A single-institution cohort
From the Journal of Dermatological Science:
Impaired function of regulatory T cells in patients with psoriasis is mediated by phosphorylation
of STAT3
Publishing Partners
Society for Investigative Dermatology (SID)
European Society for Dermatological Research (ESDR)
 February 2016
 Volume 136, Issue 2
Current Issue
This Month's Highlights
ORIGINAL ARTICLE
microRNAs in Psoriasis FREE
MicroRNAs (miRNAs) are approximately 22 nucleotide non-coding RNAs that bind
messengerRNA (mRNA) and disrupt translation into protein or trigger mRNA degradation.
MiRNAs regulate at least one third of all protein-coding genes. This review discusses those
miRNAs implicated in psoriasis.
IMMUNOLOGY/INFECTION
Prevalence of contact allergy to p-phenylenediamine (PPD) in the European general
population FREE
A cross-sectional study of over10,000 people in 5 European countries confirms a high rate of pphenylenediamine (PPD) contact allergy, especially among users of hair colorants and those with
black henna tattoos.
Photo credit: NHS choices: hair dye reactions (http://www.nhs.uk/conditions/hair-dyeallergy/Pages/Introduction.aspx
LETTER TO THE EDITOR
Distinct histologic subtypes and risk factors for early onset basal cell carcinoma: A
populationbased case control study from New Hampshire FREE
Among 1578 newly diagnosed BCCs identified in New Hampshire US, 674 occurred before age
50 years (early onset) at an average age of 43 years. Of these, 62% occurred in women and were
2.8 times more likely to have an aggressive histology than those in older patients. Sensitivity to
first seasonal sun exposure, number of painful and blistering childhood sunburns, and
recreational sun exposure were associated with BCC development in both age groups, but more
strongly in early onset cases.
Photo credit: Sand et al, Head Face Med June 4;6:7, 2010.
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Articles in Press
Most Read
Most Cited
DUX4 is de-repressed in late-differentiating keratinocytes in conjunction with
loss of H3K9me3 epigenetic repression
Orla M. Gannon, Lilia Merida de Long, Nicholas A. Saunders
DOI: http://dx.doi.org/10.1016/j.jid.2016.01.027
Publication stage: In Press Accepted Manuscript
Journal of Investigative Dermatology
Published online: February 9 2016
AbstractPDF
The alarmin IL-33 derived from HSV-2-infected keratinocytes triggers mast cellmediated antiviral innate immunity
Rui Aoki, Tatsuyoshi Kawamura, Fumi Goshima, Youichi Ogawa, Susumu
Nakae, Kohji Moriishi, Atsuhito Nakao, Shinji Shimada
DOI: http://dx.doi.org/10.1016/j.jid.2016.01.030
Publication stage: In Press Accepted Manuscript
Journal of Investigative Dermatology
Published online: February 9 2016
AbstractPDF
Plasminogen-dependent matriptase activation accelerates plasmin generation by
differentiating primary human keratinocytes
Ya-Wen Chen, Shi Yin, Ying-Jung J. Lai, Michael D. Johnson, Chen-Yong Lin
DOI: http://dx.doi.org/10.1016/j.jid.2016.01.029
Publication stage: In Press Accepted Manuscript
Journal of Investigative Dermatology
Published online: February 9 2016
AbstractPDF
Independent loss of methylthioadenosine phosphorylase (MTAP) in Primary
Cutaneous T-cell Lymphoma
Wesley J. Woollard, Nithyha P. Kalaivani, Christine L. Jones, Catherine Roper,
Lam Tung, Jae Jin Lee, Bjorn R. Thomas, Isabella Tosi, Silvia Ferreira, Carl Z.
Beyers, Robert C.T. McKenzie, Rosie M. Butler, Anna Lorenc, Sean J. Whittaker,
Tracey J. Mitchell
DOI: http://dx.doi.org/10.1016/j.jid.2016.01.028
Publication stage: In Press Accepted Manuscript
Journal of Investigative Dermatology
Published online: February 9 2016
AbstractPDF
Monosodium urate crystals induce functional expression of P2Y14 receptor in
human keratinocytes
Hideya Uratsuji, Yayoi Tada, Carren Sy Hau, Sayaka Shibata, Masahiro Kamata,
Tomohiko Kawashima, Yoshihide Asano, Makoto Sugaya, Takafumi Kadono,
Akihiko Asahina, Shinichi Sato
DOI: http://dx.doi.org/10.1016/j.jid.2016.01.026
Publication stage: In Press Accepted Manuscript
Journal of Investigative Dermatology
Published online: February 9 2016
AbstractPDF
View More Articles in Press
Most Downloaded JID Articles Published Since 2014
microRNAs in Psoriasis
Jason E. Hawkes, Giang Huong Nguyen, Mayumi Fujita, Scott R. Florell, Kristina Callis
Duffin, Gerald G. Krueger, Ryan M. O’Connell
DOI: http://dx.doi.org/10.1038/JID.2015.409
Journal of Investigative Dermatology, Vol. 136, Issue 2
AbstractFull-Text HTMLPDFSupplemental Materials
Progress toward Treatment and Cure of Epidermolysis Bullosa: Summary of the DEBRA
International Research Symposium EB2015
Jouni Uitto, Leena Bruckner-Tuderman, Angela M. Christiano, John A. McGrath,
Cristina Has, Andrew P. South, Brett Kopelan, E. Clare Robinson
DOI: http://dx.doi.org/10.1016/j.jid.2015.10.050
Journal of Investigative Dermatology, Vol. 136, Issue 2
AbstractFull-Text HTMLPDFSupplemental Materials
SnapshotDx Quiz: February 2016
Jennifer Baker, Mariya Miteva
DOI: http://dx.doi.org/10.1016/j.jid.2015.12.016
Journal of Investigative Dermatology, Vol. 136, Issue 2
AbstractPDFSupplemental Materials
Prevalence of Contact Allergy to p-Phenylenediamine in the European General
Population
Thomas L. Diepgen, Luigi Naldi, Magnus Bruze, Simone Cazzaniga, Marie-Louise
Schuttelaar, Peter Elsner, Margarida Goncalo, Robert Ofenloch, Åke Svensson
DOI: http://dx.doi.org/10.1016/j.jid.2015.10.064
Journal of Investigative Dermatology, Vol. 136, Issue 2
AbstractFull-Text HTMLPDF
Longitudinal, 3D Imaging of Collagen Remodeling in Murine Hypertrophic Scars In
Vivo Using Polarization-Sensitive Optical Frequency Domain Imaging
William C.Y. Lo, Martin Villiger, Alexander Golberg, G. Felix Broelsch, Saiqa Khan,
Christine G. Lian, William G. Austen Jr., Martin Yarmush, Brett E. Bouma
DOI: http://dx.doi.org/10.1038/JID.2015.399
Journal of Investigative Dermatology, Vol. 136, Issue 1
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