NAVBO's Vascular Biology Publication Alert
October 2015 Issue (papers published in September 2015)
NAVBO Members are highlighted in dark red
The American Journal of Pathology
Christopher Schuster, Michael Mildner, Albert Botta, Lucas Nemec, Radu Rogojanu, Lucian Beer, Christian Fiala,
Wolfgang Eppel, Wolfgang Bauer, Peter Petzelbauer, Adelheid Elbe-Bürger. Development of Blood and Lymphatic
Endothelial Cells in Embryonic and Fetal Human Skin. Am J Pathol., 185(9):2563–2574
Jie Chen, Jonette Green, Arif Yurdagul Jr., Patrick Albert, Marshall C. McInnis, A. Wayne Orr. αvβ3 Integrins
Mediate Flow-Induced NF-κB Activation, Proinflammatory Gene Expression, and Early Atherogenic
Inflammation. Am J Pathol., 185(9):2575–2589
Biochemical Journal
Oguro A, Oida S and Imaoka S. Down-regulation of EPHX2 gene transcription by Sp1 under high-glucose
conditions. Biochemical Journal, 470:281-291
Blood
No vascular biology related publications this month
Cancer Cell
No vascular biology related publications this month
Cancer Research
Ji W, Li Y, He Y, Yin M, Zhou HJ, Boggon TJ, Zhang H, Min W. AIP1 expression in tumor niche suppresses
tumor progression and metastasis. Cancer Res., 75(17):3492-504
Hughes R, Qian B-Z, Rowan C, Muthana M, Keklikoglou I, Olson OC, Tazzyman S, Danson S, Addison C, Clemons
M, Gonzalez-Angulo AM, Joyce JA, De Palma M, Pollard JW and Lewis CE. Perivascular M2 Macrophages
Stimulate Tumor Relapse after Chemotherapy. Cancer Research, 75:3479-3491
Cell
Serrels A, Lund T, Serrels B, Byron A, McPherson RC, von Kriegsheim A, Gómez-Cuadrado L, Canel M, Muir M,
Ring JE, Maniati E, Sims AH, Pachter JA, Brunton VG, Gilbert N, Anderton SM, Nibbs RJ, Frame MC. Nuclear FAK
Controls Chemokine Transcription, Tregs, and Evasion of Anti-tumor Immunity. Cell, 163(1):160-73
Clinical Science
Ching-Chih Chang, Sun-Sang Wang, Hsian-Guey Hsieh, Wen-Shin Lee, Chiao-Lin Chuang, Han-Chieh Lin, Fa-Yauh
Lee, Shou-Dong Lee, Hui-Chun Huang. Rosuvastatin improves hepatopulmonary syndrome through inhibition
of inflammatory angiogenesis of lung. Clin Sci., 129(6):449-460
María Gabriela Morales, Hugo Olguín, Gabriella Di Capua, Enrique Brandan, Felipe Simon, Claudio CabelloVerrugio. Endotoxin-induced skeletal muscle wasting is prevented by angiotensin-(1–7) through a p38 MAPKdependent mechanism. Clin Sci., 129(6):461-476
Ching-Hsia Hung, Shih-Hung Chan, Pei-Ming Chu, Kun-Ling Tsai. Homocysteine facilitates LOX-1 activation and
endothelial death through the PKCβ and SIRT1/HSF1 mechanism: relevance to human
hyperhomocysteinaemia. Clin Sci., 129(6):477-487
Mark Del Borgo, Yan Wang, Sanja Bosnyak, Morimer Khan, Pia Walters, Iresha Spizzo, Patrick Perlmutter, Lucinda
Hilliard, Kate Denton, Marie-Isabel Aguilar, Robert E. Widdop, Emma S. Jones. β-Pro7Ang III is a novel highly
selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in
conscious spontaneously hypertensive rats. Clin Sci., 129(6):505-513
Development
David M. Barry, Ke Xu, Stryder M. Meadows, Yi Zheng, Pieter R. Norden, George E. Davis and Ondine Cleaver.
Cdc42 is required for cytoskeletal support of endothelial cell adhesion during blood vessel formation.
Development, 142(17):3058-70
Manderfield LJ, Aghajanian H, Engleka KA, Lim LY, Liu F, Jain R, Li L, Olson EN and Epstein JA. Hippo signaling is
required for Notch-dependent smooth muscle differentiation of neural crest. Development, 142:2962-2971
Palpant NJ, Pabon L, Roberts M, Hadland B, Jones D, Jones C, Moon RT, Ruzzo WL, Bernstein I, Zheng Y and
Murry CE. Inhibition of β-catenin signaling respecifies anterior-like endothelium into beating human
cardiomyocytes. Development, 142:3198-3209
Yu JA, Castranova D, Pham VN and Weinstein BM. Single-cell analysis of endothelial morphogenesis in vivo.
Development, 142:2951-2961
Developmental Biology
Jang DG, Sim HJ, Song EK, Medina-Ruiz S, Seo JK and Park TJ. A thioredoxin fold protein Sh3bgr regulates
Enah and is necessary for proper sarcomere formation. Developmental Biology, 405:1-9
Developmental Cell
No vascular biology related publications this month
Developmental Dynamics
No vascular biology related publications this month
EMBO
F. Tuorto, F. Herbst, N. Alerasool, S. Bender, O. Popp, G. Federico, S. Reitter, R. Liebers, G. Stoecklin, H. J. Grone, G.
Dittmar, H. Glimm and F. Lyko. The tRNA methyltransferase Dnmt2 is required for accurate polypeptide
synthesis during haematopoiesis. EMBO J, 34: 2350-2362
EMBO Reports
No vascular biology related publications this month
FASEB Journal
P. Amadio, D. Baldassarre, E. Tarantino, E. Zacchi, S. Gianellini, I. Squellerio, M. Amato, B. B. Weksler, E. Tremoli
and S. S. Barbieri. Production of prostaglandin E2 induced by cigarette smoke modulates tissue factor
expression and activity in endothelial cells. FASEB J, 29:4001-4010
C. T. Kesler, E. R. Pereira, C. H. Cui, G. M. Nelson, D. J. Masuck, J. W. Baish and T. P. Padera. Angiopoietin-4
increases permeability of blood vessels and promotes lymphatic dilation. FASEB J, 29:3668-3677
K. A. Parham, J. R. Zebol, K. L. Tooley, W. Y. Sun, L. M. Moldenhauer, M. P. Cockshell, B. L. Gliddon, P. A. Moretti,
G. Tigyi, S. M. Pitson and C. S. Bonder. Sphingosine 1-phosphate is a ligand for peroxisome proliferatoractivated receptor-gamma that regulates neoangiogenesis. FASEB J, 29:3638-3653
Genes & Development
No vascular biology related publications this month
Journal of Biological Chemistry
P. Koenig, C. V. Lee, S. Sanowar, P. Wu, J. Stinson, S. F. Harris and G. Fuh. Deep Sequencing-guided Design of a
High Affinity Dual Specificity Antibody to Target Two Angiogenic Factors in Neovascular Age-related Macular
Degeneration. J Biol Chem, 290:21773-21786
A. C. Mar, C. H. Chu, H. J. Lee, C. W. Chien, J. J. Cheng, S. H. Yang, J. K. Jiang and T. C. Lee. Interleukin-1
Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth
Factor A in Colon Cancer Cells and Induce Angiogenesis. J Biol Chem, 290:22212-22224
A. M. Orogo, E. R. Gonzalez, D. A. Kubli, I. L. Baptista, S. B. Ong, T. A. Prolla, M. A. Sussman, A. N. Murphy and A.
B. Gustafsson. Accumulation of Mitochondrial DNA Mutations Disrupts Cardiac Progenitor Cell Function and
Reduces Survival. J Biol Chem, 290:22061-22075
P. R. Ortiz de Montellano. Heme and I. J Biol Chem, 290:21833-21844
Y. Cao, S. Zhang, N. Yuan, J. Wang, X. Li, F. Xu, W. Lin, L. Song, Y. Fang, Z. Wang, Z. Wang, H. Zhang, Y. Zhang, W.
Zhao, S. Hu, X. Zhang and J. Wang. Hierarchal Autophagic Divergence of Hematopoietic System. J Biol Chem,
290:23050-23063
M. B. Nijaguna, V. Patil, S. Urbach, S. D. Shwetha, K. Sravani, A. S. Hegde, B. A. Chandramouli, A. Arivazhagan, P.
Marin, V. Santosh and K. Somasundaram. Glioblastoma-derived Macrophage Colony-stimulating Factor (MCSF)
Induces Microglial Release of Insulin-like Growth Factor-binding Protein 1 (IGFBP1) to Promote
Angiogenesis. J Biol Chem, 290:23401-23415
L. Yan, S. Lee, D. R. Lazzaro, J. Aranda, M. B. Grant and B. Chaqour. Single and Compound Knock-outs of
MicroRNA (miRNA)-155 and Its Angiogenic Gene Target CCN1 in Mice Alter Vascular and Neovascular Growth
in the Retina via Resident Microglia. J Biol Chem, 290:23264-23281
N. Das, L. Xie, S. K. Ramakrishnan, A. Campbell, S. Rivella and Y. M. Shah. Intestine-specific Disruption of
Hypoxia-inducible Factor (HIF)-2alpha Improves Anemia in Sickle Cell Disease. J Biol Chem, 290:23523-23527
A. Foryst-Ludwig, M. C. Kreissl, V. Benz, S. Brix, E. Smeir, Z. Ban, E. Januszewicz, J. Salatzki, J. Grune, A. K.
Schwanstecher, A. Blumrich, A. Schirbel, R. Klopfleisch, M. Rothe, K. Blume, M. Halle, B. Wolfarth, E. E. Kershaw
and U. Kintscher. Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the
Lipokine C16:1n7-Palmitoleate. J Biol Chem, 290:23603-23615
Journal of Cell Biology
Vandersmissen I, Craps S, Depypere M, Coppiello G, van Gastel N, Maes F, Carmeliet G, Schrooten J, Jones EA,
Umans L, Devlieger R, Koole M, Gheysens O, Zwijsen A, Aranguren XL, Luttun A. Endothelial Msx1 transduces
hemodynamic changes into an arteriogenic remodeling response. J Cell Biol., 210(7):1239-56
Journal of Cell Science
No vascular biology related publications this month
Journal of Clinical Investigation
Liao X, Zhang R, Lu Y, Prosdocimo DA, Sangwung P, Zhang L, Zhou G, Anand P, Lai L, Leone TC, Fujioka H, Ye F,
Rosca MG, Hoppel CL, Schulze PC, Abel ED, Stamler JS, Kelly DP, Jain MK. Kruppel-like factor 4 is critical for
transcriptional control of cardiac mitochondrial homeostasis. J Clin Invest., 125(9):3461-76
Kazenwadel J, Betterman KL, Chong CE, Stokes PH, Lee YK, Secker GA, Agalarov Y, Demir CS, Lawrence DM,
Sutton DL, Tabruyn SP, Miura N, Salminen M, Petrova TV, Matthews JM, Hahn CN, Scott HS, Harvey NL. GATA2
is required for lymphatic vessel valve development and maintenance. J Clin Invest., 125(8):2979-94
Boscolo E, Limaye N, Huang L, Kang KT, Soblet J, Uebelhoer M, Mendola A, Natynki M, Seront E, Dupont S,
Hammer J, Legrand C, Brugnara C, Eklund L, Vikkula M, Bischoff J, Boon LM. Rapamycin improves TIE2mutated venous malformation in murine model and human subjects. J Clin Invest., 125(9):3491-504
Journal of Experimental Medicine
Ridder DA, Wenzel J, Müller K, Töllner K, Tong XK, Assmann JC, Stroobants S, Weber T, Niturad C, Fischer L,
Lembrich B, Wolburg H, Grand'Maison M, Papadopoulos P, Korpos E, Truchetet F, Rades D, Sorokin LM, SchmidtSupprian M, Bedell BJ, Pasparakis M, Balschun D, D'Hooge R, Löscher W, Hamel E, Schwaninger M. Brain
endothelial TAK1 and NEMO safeguard the neurovascular unit. J Exp Med., 212(10):1529-49
Journal of Immunology
Hossain M, Qadri SM, Xu N, Su Y, Cayabyab FS, Heit B, Liu L. Endothelial LSP1 Modulates Extravascular
Neutrophil Chemotaxis by Regulating Nonhematopoietic Vascular PECAM-1 Expression. J Immunol.,
195(5):2408-16
Journal of Lipid Research
No vascular biology related publications this month
Molecular and Cellular Biology
No vascular biology related publications this month
Molecular Biology of the Cell
Sankar P. Chaki, Rola Barhoumi, and Gonzalo M. Rivera. Actin remodeling by Nck regulates endothelial lumen
formation. Mol. Biol. Cell, 26(17):3047-3060
Leslie Pomeraniec, Melissa Hector-Greene, Marcelo Ehrlich, Gerard C. Blobe, and Yoav I. Henis. Regulation of
TGF-β receptor hetero-oligomerization and signaling by endoglin. Mol. Biol. Cell, 26(17):3117-3127
Nature
Ronen Durst, Kimberly Sauls, David S. Peal, Annemarieke deVlaming, Katelynn Toomer, Maire Leyne, Monica
Salani, Michael E. Talkowski, Harrison Brand, Maëlle Perrocheau, Charles Simpson, Christopher Jett, Matthew R.
Stone, Florie Charles, Colby Chiang, Stacey N. Lynch, Nabila Bouatia-Naji, Francesca N. Delling, Lisa A. Freed,
Christophe Tribouilloy, Thierry Le Tourneau, Hervé LeMarec, Leticia Fernandez-Friera, Jorge Solis, Daniel Trujillano,
Stephan Ossowski, Xavier Estivill, Christian Dina, Patrick Bruneval, Adrian Chester, Jean-Jacques Schott, Kenneth
D. Irvine, Yaopan Mao, Andy Wessels, Tahirali Motiwala, Michel Puceat, Yoshikazu Tsukasaki, Donald R. Menick,
Harinath Kasiganesan, Xingju Nie, Ann-Marie Broome, Katherine Williams, Amanda Johnson, Roger R. Markwald,
Xavier Jeunemaitre, Albert Hagege, Robert A. Levine, David J. Milan, Russell A. Norris & Susan A. Slaugenhaupt.
Mutations in DCHS1 cause mitral valve prolapse. Nature, 525(7567):109–113
Ke Wei, Vahid Serpooshan, Cecilia Hurtado, Marta Diez-Cuñado, Mingming Zhao, Sonomi Maruyama, Wenhong
Zhu, Giovanni Fajardo, Michela Noseda, Kazuto Nakamura, Xueying Tian, Qiaozhen Liu, Andrew Wang, Yuka
Matsuura, Paul Bushway, Wenqing Cai, Alex Savchenko, Morteza Mahmoudi, Michael D. Schneider, Maurice J. B.
van den Hoff, Manish J. Butte, Phillip C. Yang, Kenneth Walsh, Bin Zhou, Daniel Bernstein, Mark Mercola & Pilar
Ruiz-Lozano. Epicardial FSTL1 reconstitution regenerates the adult mammalian heart. Nature, 525(7570):479–
485
Nature Cell Biology
No vascular biology related publications this month
Nature Genetics
No vascular biology related publications this month
Nature Medicine
Anna Cantalupo, Yi Zhang, Milankumar Kothiya, Sylvain Galvani, Hideru Obinata, Mariarosaria Bucci, Frank J
Giordano, Xian-Cheng Jiang, Timothy Hla and Annarita Di Lorenzo. Nogo-B regulates endothelial sphingolipid
homeostasis to control vascular function and blood pressure. Nature Medicine, 21(9):1028–1037
Jesmond Dalli, Nan Chiang and Charles N Serhan. Elucidation of novel 13-series resolvins that increase with
atorvastatin and clear infections. Nature Medicine, 21(9):1071–1075
PNAS
Kunert C, Baish JW, Liao S, Padera TP, Munn LL. Mechanobiological oscillators control lymph flow. Proc Natl
Acad Sci U S A, 112(35):10938-43
Kanatani S, Honda T, Aramaki M, Hayashi K, Kubo K, Ishida M, Tanaka DH, Kawauchi T, Sekine K, Kusuzawa S,
Kawasaki T, Hirata T, Tabata H, Uhlén P, Nakajima K. The COUP-TFII/Neuropilin-2 is a molecular switch steering
diencephalon-derived GABAergic neurons in the developing mouse brain. Proc Natl Acad Sci U S A,
112(36):E4985-94
Liu CH, Sun Y, Li J, Gong Y, Tian KT, Evans LP, Morss PC, Fredrick TW, Saba NJ, Chen J. Endothelial microRNA150 is an intrinsic suppressor of pathologic ocular neovascularization. Proc Natl Acad Sci U S A,
112(39):12163-8
Science
No vascular biology related publications this month
Member Submissions
Guzzardi DG, Barker AJ, van Ooij P, Malaisrie SC, Puthumana JJ, Belke DD, Mewhort HE, Svystonyuk DA, Kang S,
Verma S, Collins J, Carr J, Bonow RO, Markl M, Thomas JD, McCarthy PM, Fedak PW. Valve-Related
Hemodynamics Mediate Human Bicuspid Aortopathy: Insights From Wall Shear Stress Mapping. J Am Coll
Cardiol., 66(8):892-900
Jongman RM, van Klarenbosch J, Molema G, Zijlstra JG, de Vries AJ, van Meurs M. Angiopoietin/Tie2 Dysbalance
Is Associated with Acute Kidney Injury after Cardiac Surgery Assisted by Cardiopulmonary Bypass. PLoS
One., 10(8):e0136205
Prabhakar P, Zhang H, Chen D, Faber JE. Genetic variation in retinal vascular patterning predicts variation in
pial collateral extent and infarct volume after middle cerebral artery occlusion. Angiogenesis, 18(1):97-114
Moore SM, Zhang H, Maeda N, Doerschuk, Faber JE. Cardiovascular risk factors cause premature rarefaction
of the collateral circulation and greater ischemic tissue injury. Angiogenesis, 18:265-281
Zhang H, Faber JE. De-novo collateral formation following acute myocardial infarction: Dependence on
CCR2+ bone marrow cells. J Molec Cell Cardiol., 87:4-16
Shibasaki M, Wang JG, Figueiredo JL, New SE, Quillard T, Goettsch C, Koga JI, Sonoki H, Matsumoto J, Aikawa M,
Aikawa E. Pitavastatin Reduces Inflammation in Atherosclerotic Plaques in Apolipoprotein E-Deficient Mice
with Late Stage Renal Disease. PLoS One, 10(9):e0138047
Chow W, Amaya CN, Rains S, Chow M, Dickerson EB, Bryan BA. Growth Attenuation of Cutaneous
Angiosarcoma With Propranolol-Mediated β-Blockade. JAMA Dermatol.,16:1-4
Kheirolomoom A, Kim CW, Seo JW, Kumar S, Son DJ, Gagnon MK, Ingham ES, Ferrara KW, Jo H. Multifunctional
Nanoparticles Facilitate Molecular Targeting and miRNA Delivery to Inhibit Atherosclerosis in ApoE(-/-) Mice.
ACS Nano., 9(9):8885-97
Lola A. Brown, Parid Sava, Cesar Garcia, Anjelica L. Gonzalez. Proteomic Analysis of the Pericyte Derived
Extracellular Matrix. Cellular and Molecular Bioengineering, 8(3):349-363
Pedrosa AR, Trindade A, Carvalho C, Graça J, Carvalho S, Peleteiro MC, Adams RH, Duarte A.
Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions.
Oncotarget, 6(27):24404-23