CELL REPRODUCTION Chapter 8 1. DNA molecules twist into tightly packed chromosomes. These chromosomes are made up of segments called genes. Chromosomes direct all chemical reactions that determine inherited traits in organisms. 2. Each species is unique due to number of chromosomes & arrangement of genes on the chromosomes. 3. Chromosome structure: a) thin strands of DNA called chromatin twist into thick strands called chromatids & can be easily seen with a microscope b) chromosome is formed when 2 chromatids are held together by a centromere 4. Body cells are called somatic cells & are diploid because they contain both chromosomes of each homologous pair. 5. Sex cells (sperm & egg) are haploid & contain only 1 chromosome from each homologous pair. 6. For growth & repair, cell numbers are constantly increasing. This occurs in a continuous series of events called the cell cycle. a) most of cell’s life is spent in interphase: 1) G1 Phase - rapid growth in size & organelle number 2) S Phase - DNA replication 3) G2 Phase - growth & preparation for division b) M Phase - mitosis - nucleus divides c) cytokinesis - splitting of the cell into 2 new cells identical to original cell 7. Once body cells reach maximum size, the phases of mitosis begin: 1st - prophase: 1) chromatin coils tightly into chromosomes 2) nucleolus & nuclear membrane breakdown & disappear 3) centrioles appear & move toward poles 4) spindle fibers develop & extend between centrioles 2nd - metaphase: chromosomes line up along spindle fibers at the equator 3rd - anaphase: centromere of each chromosome divides & chromatids separate & move toward opposite poles 4th - telophase: 1) identical sets of chromatids cluster at opposite poles 2) centrioles & spindle fibers disappear while nuclear membrane & nucleolus reappear 3) cleavage furrow forms as membrane pinches inward at cell’s equator to separate the 2 new nuclei & other organelles 8. Gametes (sex cells - sperm & egg) form in a process called meiosis when the number of chromosomes is reduced by half to allow sperm & eggs to contain only 1 chromosome from each homologous pair. When fertilization occurs, homologous pairs join & produce inherited characteristics of the offspring. The zygote formed when egg is fertilized by a sperm is a diploid cell. 9. Meiosis is 2 different divisions involving of prophase, metaphase, anaphase, & telophase. 1 diploid cell becomes 4 haploid cells: 1st - meiosis I: parent cell produces 2 daughter cells that each contains 1 chromosome from each homologous pair - because of replication, each chromosome has twice the amount of original DNA 2nd - meiosis II: does not involve replication - within nuclei of each cell, chromatids separate & 4 daughter cells with half the original number of chromosomes are created from original parent cell 10. A mistake called nondisjunction may occur during meiosis when chromosomes fail to separate correctly. 1 daughter cell receives an extra chromosome & the other daughter cell is missing a chromosome. Organisms with extra chromosomes often survive, but those lacking chromosomes usually do not. 11. Every species of living things must reproduce or it will face extinction. Depending on the species, offspring may be produced by asexual or sexual reproduction. a) asexual reproduction does not involve the union of sperm & eggs – many offspring can be produced in a short time, but the offspring are genetically identical to the parent 1) binary fission – cell division (bacteria & protists) 2) budding – an outgrowth of the parent (hydra & sponges) 3) fragmentation – breaking & regrowth (starfish) b) sexual reproduction produces offspring through the union of sperm & eggs – this increases genetic variety among species & enables them to more easily adjust to changing environments