上海中医药大学研究生导师信息表 姓 名 出生年月 刘平 性 别 男 民 族 汉 1953.8 学 历 研究生 学 位 博士 技术职称 教授、研究员 导 类 师 别 二级学院 曙光医院/肝病研究所 职 务 从事专业 中医内科学 研究方向 博士生导师 专业 代码 100506 中医药防治慢性肝病的临床与基础研究 [1] Zhou Y. N., Sun M. Y., Mu Y. P., Yang T., Ning B. B., Ren S., Chen J. M., Liu P. Xuefuzhuyu decoction inhibition of angiogenesis attenuates liver fibrosis induced by CCl(4) in mice[J]. J Ethnopharmacol,2014,153(3):659-666. [2] Wang Xiaoning, Xie Guoxiang, Wang Xiaoyan, Zhou Mingmei, Yu Huan, Lin Yan, Du Guangli, Luo Guoan, Liu Ping. Urinary Metabolite Profiling Offers Potential for Differentiation of Liver-Kidney Yin Deficiency and Dampness-Heat Internal Smoldering Syndromes in Post-Hepatitis B Cirrhosis Patients[J]. Evidence-Based Complementary and Alternative Medicine,2014,vol. 2014, Article ID 464969, 11 pages, 2014. doi:10.1155/2014/464969. [3] Zhang L. J.,Sun M. Y.,Ning B. B.,Zhang W. M.,Chen G. F.,Mu Y. P.,Zhang H., Liu J.,Bian Y. Q.,Liu P. Xiayuxue Decoction (下淤血汤) attenuates hepatic stellate cell activation and sinusoidal endothelium defenestration in CCl4-induced fibrotic liver of mice[J]. Chin J Integr Med,2014,20(7):516-523. [4] Li Qing-Ya, Guo Zhi-Zhong, Deng Xin, Xu Lie-Ming, Gao Yue-Qiu, Zhang Wei, Wang Xiao-Su, Xue Dong-Ying, Lu Yi-Yu, Liu Ping, Su Shi-Bing. Curative Effects of 近五年研究 成果 ZHENG-Based Fuzheng-Huayu Tablet on Hepatitis B Caused Cirrhosis Related to CYP1A2 Genetic Polymorphism[J]. Evidence-Based Complementary and Alternative Medicine,2013,2013:7. [5] Yin X., Peng J., Zhao L., Yu Y., Zhang X., Liu P., Feng Q., Hu Y., Pang X. Structural changes of gut microbiota in a rat non-alcoholic fatty liver disease model treated with a Chinese herbal formula[J]. Syst Appl Microbiol,2013,36(3):188-196. [6] Jiang P., Shi R., Wang Q., Ma Y. M., Cui H. Y., Liu P., Liu C. H. Simultaneous determination of eleven major components in Fugan Fang using high-performance liquid chromatography coupled with mass spectrometry[J]. Biomed Chromatogr,2013,27(7):874-881. [7] Deng Yan-Ru, Ma Hong-Di, Tsuneyama Koichi, Yang Wei, Wang Yin-Hu, Lu Fang-Ting, Liu Cheng-Hai, Liu Ping, He Xiao-Song, Diehl Anna Mae, Gershwin M. Eric, Lian Zhe-Xiong. STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib[J]. Journal of Autoimmunity,2013,46:25-34. [8] Gou X., Tao Q., Feng Q., Peng J., Zhao Y., Dai J., Wang W., Zhang Y., Hu Y., Liu P. Urine metabolic profile changes of CCl4-liver fibrosis in rats and intervention effects of Yi Guan Jian Decoction using metabonomic approach[J]. BMC Complement Altern Med,2013,13:123. [9] Gou X., Tao Q., Feng Q., Peng J., Sun S., Cao H., Zheng N., Zhang Y., Hu Y., Liu P. Urinary metabonomics characterization of liver fibrosis induced by CCl(4) in rats and intervention effects of Xia Yu Xue Decoction[J]. J Pharm Biomed Anal,2013,74:62-65. [10] Liu P. Fuzheng huayu capsule in the treatment of liver fibrosis: clinical evidence and mechanism of action[J]. Chin J Integr Med,2012,18(5):398-400. [11] Wang Xiaoning, Wang Xiaoyan, Xie Guoxiang, Zhou Mingmei, Yu Huan, Lin Yan, Du Guangli, Luo Guoan, Jia Wei, Liu Ping. Urinary Metabolite Variation is Associated with Pathological Progression of the Post-Hepatitis B Cirrhosis Patients[J]. J Proteome Res,2012,11(7):3838-3847. [12] Zhang H., Lv H., Huang P. X., Lin Y., Hu X. C., Liu P. Comparative Study of TCM Syndrome Scale for Liver Disease and Chronic Liver Disease Questionnaire Based on Assessment of Posthepatitic Cirrhosis[J]. Evid Based Complement Alternat Med,2012,2012:496575. [13] Du J. X., Sun M. Y., Du G. L., Li F. H., Liu C., Mu Y. P., Chen G. F., Long A. H., Bian Y. Q., Liu J., Liu C. H., Hu Y. Y., Xu L. 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Huangqi decoction inhibits apoptosis and fibrosis, but promotes Kupffer cell activation in dimethylnitrosamine-induced rat liver fibrosis[J]. BMC Complement Altern Med,2012,12:51. [18] Yao C., Tang N., Xie G., Zheng X., Liu P., Fu L., Xie W., Yao F., Li H., Jia W. Management of hepatic encephalopathy by traditional chinese medicine[J]. Evid Based Complement Alternat Med,2012,2012:835686. [19] Liu P. Modern research of TCM etiology and pathogenesis theory and translational medicine[J]. Journal of Translational Medicine,2012,10(Suppl 2):A36. [20] Chen Yue-Lei, Lv Jing, Ye Xiao-Lei, Sun Ming-Yu, Xu Qin, Liu Cheng-Hai, Min Li-Hua, Li Hui-Ping, Liu Ping, Ding Xiaoyan. Sorafenib inhibits transforming growth factor β 1-Mediated Epithelial-Mesenchymal Transition and apoptosis in mouse hepatocytes[J]. Hepatology,2011,53(5):1708-1718. [21] Fu W. W., Fu J. N., Zhang W. M., Sun L. X., Pei Y. H., Liu P. Platycoside O, a new triterpenoid saponin from the roots of Platycodon grandiflorum[J]. Molecules,2011,16(6):4371-4378. [22] Fu Wen-Wei, Tan Chang-Heng, Zhuang Peng-Yu, Yang Shu-Min, Luo Hong-Feng, Tan Jun-Jie, Liu Ping, Zhu Da-Yuan. Purinium Derivatives with Antitumor Activities from Heterostemma alatum Wight[J]. Heterocycles,2011,6(83):1405-1408. [23] Zhang W. M., Fu W. W., Sun M. Y., Sun L. X., Jia Y. R., Liu P. Simultaneous determination of five nucleosides and nucleobases of Rehmannia glutinosa Libosch. by high performance liquid chromatography[J]. Yao Xue Xue Bao,2011,46(11):1380-1384. [24] Chen T., Xie G., Wang X., Fan J., Qiu Y., Zheng X., Qi X., Cao Y., Su M., Wang X., Xu L. X., Yen Y., Liu P., Jia W. Serum and urine metabolite profiling reveals potential biomarkers of human hepatocellular carcinoma[J]. Mol Cell Proteomics,2011,10(7):M110-M4945. [25] Liu C., Tao Q., Sun M., Wu J. Z., Yang W., Jian P., Peng J., Hu Y., Liu C., Liu P. Kupffer cells are associated with apoptosis, inflammation and fibrotic effects in hepatic fibrosis in rats[J]. Lab Invest,2010,90(12):1805-1816. [26] Hu X. D., Jiang S. L., Liu C. H., Hu Y. Y., Liu C., Sun M. Y., Chen G. F., Liu P. Preventive effects of 1,25-(OH)2VD3 against ConA-induced mouse hepatitis through promoting vitamin D receptor gene expression[J]. Acta Pharmacol Sin,2010,31(6):703-708. *请按课题名称、课题级别及来源、课题经费**万元填写 目前在研课 题 招生 类别 扶正化瘀片抗肝纤维化的美国Ⅲ期临床试验前研究,国家科技重大专项 (重大新药创制),1400 万元 基于 Smad7 蛋白表达调控解析黄芪总皂苷与甘草酸配伍抗肝纤维化的 效应机制,国家自然科学基金面上项目,75 万元 扶正化瘀方抗肝纤维化作用机制的网络药理学及其关键技术研究,上海 市科委,60 万元 茵陈蒿汤片创新药物的临床研究,国家科技部重大新药专项,400 万元 学生 类别 博士生/硕士生 学位类别 科学学位