DNA and PROTEIN SYNTHESIS Study Guide Name:________________________________________________________ per____ 1. DNA and RNA are both polymers. What is the name for this type of polymer and what do we call the monomer that makes them up? Polymer- nucleic acid Monomer- nucleotides 2. What are the three types of RNA. Messenger, ribosomal and transfer 3. Place a checkmark in the box if the statement applies to that kind of RNA. mRNA rRNA tRNA Made in the nucleus Used in protein production X X X X Carries amino acids Makes up a ribosome X X Nucleic Acid Has Codons X X X X X X Has Anticodons Made of nucleotides X 4. Describe the following: (including what is being made and where it occurs) a. Replication DNA DNA (IN NUCLEUS) b. Transcription DNA RNA (IN NUCLEUS) c. X X X Translation RNA PROTEIN (IN CYTOPLASM ON RIBOSOME) Remember: What order do the above processes occur in? Transcription before Translation (Replication is independent) 5. Be as specific and complete as possible. How does DNA code for a protein? The order of nucleotides in a gene (DNA) carries a code of what order to put amino acids in to make a protein. Since DNA can’t leave the nucleus, it must be TRANSCRIBED into a strand of mRNA. mRNA then leaves the nucleus to meet up with the ribosome (rRNA). The ribosome “reads” the code by allowing tRNA molecules to add amino acids to the chain one by one in the correct order. tRNA’s float around in the nucleus carrying their specific amino acid waiting to be “called on” by the ribosome. Once the ribosome is on the CODON (mRNA) that matches the tRNA’s ANTICODON, it will match up (codon to anticodon) and transfer it’s amino acid from the tRNA to the amino acid chain. If any of these lines of code are known, the others can be determined: DNA mRNA tRNA protein TAC ATG CTA GGT AUG UAC GAU CCA UAC AUG CUA GGU Methionine Tyrosine Aspartate Proline Fill in the blanks. ATC UAG AUC STOP GCT CGA GCU Arginine CAC GUG CAC Valine GGT CCA GGU Proline DNA mRNA ATG UAC TAC AUG GAT CUA CCA GGU TAG AUC CGA GCU GTG CAC CCA GGU tRNA protein AUG Tyrosine UAC Methionine GAU CCA UAG CGA GUG CCA Leucine Glycine Isoleucine Alanine Histidine glycine DNA mRNA tRNA TAC AUG UAC ATG UAC AUG CTA GAU CUA GGT CCA GGU ATC UAG AUC GCT CGA GCU CAC GUG CAC GGT CCA GGU protein Methionine Tyrosine Aspartate Proline STOP Arginine Valine Proline 1. What are the 3 base sections of mRNA called?_______codons________ 2. What are the 3 base sections of tRNA called?________anticodons__________________ 3. What do you notice about DNA and tRNA? Why could you have predicted this? They are both complementary to the mRNA, so they are the same except for the U’s and T’s 4. In table one, you use the DNA blueprint of bases to make RNA. This is called transcription. 5. You then make a string of amino acids to form a __protein______________. 6. What is that process called (when you join amino acids using the RNA as a blueprint?) translation