CURRICULUM VITAE William Marvin McClellan, Jr., M.D., M.P.H. Office Address: Emory University Rollins School of Public Health 1518 Clifton Road NE Rm 458 Atlanta, GA 30322 Telephone: (404) -727-6976 Fax: (404) -727-8737 E-mail Address wmcclel@sph.emory.edu Birth Date and Place: March 30, 1947, Alexandria, VA Citizenship: US Current Titles and Affiliations: Academic appointments: I. Primary appointments: Professor, Department of Epidemiology, Rollins School of Public Health, Emory University School of Medicine, 2012-present Professor, Department of Medicine, Division of Renal Medicine, Emory University School of Medicine, 2005-2012 II. Joint and secondary appointments: Professor, Department of Medicine, Division of Renal Medicine, Emory University School of Medicine, 2012-present Professor, Department of Epidemiology, Rollins School of Public Health, Emory University School of Medicine, 2005-12 Associate Professor, Division of Nephrology, Department of Medicine, University of Alabama at Birmingham 2004-2010 Previous Academic and Professional Appointments: I. Clinical Assistant Professor, Department of Medicine, Division of Hypertension, Emory University School of Medicine, 1976-1991 II. Clinical Associate Professor, Department of Medicine, Division of Renal Medicine, Emory University School of Medicine, 1991-1999 III. Clinical Professor, Department of Medicine, Division of Renal Medicine, Emory University School of Medicine, 1999-2005 Licensures/Boards: Georgia. 017629. Issued 1976. American Board Internal Medicine. 52806. 1975. W.M. McClellan, Jr. -p. 2 - Education: B.S.1972 M.S. 1972 . University of Alabama, Birmingham, Alabama University of Alabama, Birmingham, Alabama (Thesis: A proposed model for amino acid transport in the Ehrlich ascites cell). University of Alabama, Birmingham, Alabama Emory University, Atlanta, Georgia. (Thesis: Diet and Risk of early mortality among end-stage renal disease patients treated by dialysis: A prospective cohort study.) M.D. 1972 M.P.H. 1992 Postgraduate Training: Internship 1972-1973 Residency 1973-1974 Fellowship 1974-1975 Straight Medicine Hospital of the University of Pennsylvania Straight Medicine Hospital of the University of Pennsylvania Renal Medicine, Cardiovascular Research Institute, University of California, San Francisco Participant 1980 The Dynamics of Health Services Systems: Strategic Planning for Complex Health Organizations, Massachusetts Institute of Technology Participant 1985 New England Epidemiology Institute Computers in Epidemiology; Logistic Regression and Survival Analysis; Nutritional Epidemiology; University of Massachusetts, Amherst. Participant 1998 Measurement, design and analysis methods for health outcomes research, Harvard School of Public Health, Boston Committee Memberships: National and International: American Kidney Fund Member Selection Committee, AKF Clinical Scholar Program. 1993-1997 Trustee. 1995-1997 American Society of Nephrology Member. Chronic Kidney Disease Advisory Group 2003-2009. National Institutes of Health Member. Working Group for the Development Of NHBPEP Guide for Community High Blood Pressure Control, National High Blood Pressure Education Program. 1979-1980 Consultant. National High Blood Pressure Education Program. 1978-1986 Member. Working Group on Health Education in HBP Control, National High Blood Pressure Program. 1984-1987 Member. Physician Survey Advisory Panel, National High Blood Pressure Education Program. 1985-1986 2 W.M. McClellan, Jr. -p. 3 - Member. Data Safety and Monitoring Committee, Dialysis Access Consortium (DAC) Clopidogrel Prevention of Early AV Fistula Thrombosis Trial, NIDDK. 2005 2007 Member. Scientific Advisory Committee, AV Fistula Maturation Cohort Study. NIDDK. 2009 Member. Steering Committee for the NIDDK National Kidney Disease Education Program. 2001-present Chairman. Scientific Advisory Committee. AASK Nocturnal Blood Pressure Pilot Study, NIDDK. 2007-2012 Chairman. Scientific Advisory Committee. Chronic Kidney Disease Cohort Study, NIDDK. 2002-present National Kidney Foundation Member. Kidney Early Evaluation Program (KEEP) Executive Committee. 2003-2008 Member. President’s Advisory Council 2004-2008 National Kidney Foundation Singapore Member. Medical Advisory Committee. 1998-2003. Roche Foundation for Anemia Research Member. Scientific Advisory Board. 2004-2009. Norman S. Coplon Extramural Grant Program, Satellite Dialysis Member. Scientific Advisory Board. 2005-2010. Editorships and Editorial Boards Editorial Boards Patient Education and Counseling American Journal of Kidney Disease Clinical Journal American Society Nephrology 1984-1988 1995-2000 2010-present Editorships Journal of American Society of Nephrology Associate Editor, 2001-2007 Manuscript reviewer: (all current) New England Journal of Medicine JAMA American Journal Kidney Disease Kidney International Nephrology, Dialysis and Transplantation JASN CJASN AJN 3 W.M. McClellan, Jr. -p. 4 - Honors and Awards: Bronze Medal for Service, American Heart Association-Georgia Affiliate, 1984. Best Professor, 1999. Selected by student government, Rollins School of Public Health, Emory University Society Memberships: American Society of Nephrology American Association for Advancement of Science Research focus: My current research seeks to understand and reduce racial and socioeconomic (SES) disparities in the treatment and outcomes of patients with kidney disease. Part of this work focuses understanding how chronic disease surveillance systems (the Medicare ESRD Networks and Quality Improvement Organizations) can be used to improve quality of care of ESRD patients. A second emphasis is working to understand the role of SES and race on the occurrence and progression of chronic kidney disease (CKD). Most recently we have begun to examine the association between geospatial factors and the detection, treatment and outcomes of CKD Grant Support: Previous: Special Study Contract with CMS (SS-GA-03) for GMCF contract number 500-02-GA02. Chronic Kidney Disease Pilot Intervention. $860,405. 25%FTE. 9/30/03-10/31/05. Special Study Contract with CMS (SS-GA-0009) for GMCF contract number 500-02-GA02. Academic Medical Center Intervention. $560,448. 25% FTE. 9/03/03-10/31/05. REGARDS - #0000001670 (Funded by an unrestricted grant from AMGEN to UAB) “Renal Ancillary Study of the REGARDS Study (Renal REGARDS) The objective of this study is to determine if anemia and chronic kidney disease are important variables that contribute to the incidence of new cerebrovascular events during the 5 years of the follow-up of the REGARDS cohort. Role: PI (40% FTE). 04/01/08 – 03/31/11 AMGEN - #108074 “Psychological burden of anemia and chronic kidney disease in the REGARDS Study (Renal REGARDS) The objective of this study is to determine if anemia and chronic kidney disease are important variables that contribute to increased disease burden among in the REGARDS cohort. Role: PI (20% FTE). 01/01/09 – 01/01/12 Clinical Service: Nephrology Fellow’s Clinic Attending. Monthly at Grady Memorial Hospital, Grady Health System, 80 Jesse Hill Jr. Dr. SE, Atlanta, GA 30303. 1998-present Medicine ward attending. One to two months yearly at Grady Memorial Hospital. 1977-1986 & 1990-2011 Formal Teaching: Course Director. Epidemiology of Chronic Disease Fall Semester, Emory University, Rollins School of Public Health. 1990-present 4 W.M. McClellan, Jr. -p. 5 - Course Director. Epidemiology of Cardiovascular Disease, Spring Semester, Emory University, Rollins School of Public Health. 1995-present Course Director. Epidemiology of Aging, Spring semester, Emory University, Rollins School of Public Health. 2010-present Supervisory Teaching: Ph.D. students directly supervised: J. Michael Soucie Title: Epidemiology of Kidney Stones in the United States. 1994 Kathryn Alexis Kohler. Title: The Epidemiology of Microalbuminuria in African-American with Type 2 Diabetes. 1999. Jean-Christophe Luthi. Title: Validity and reliability of routinely collected quality indicators to monitor process and outcome of care in Swiss academic medical centers. 2002. Nataliya Volkova. Title: Understanding racial disparities in end-stage renal disease incidence, treatment, and survival: The role of socioeconomic and environmental factors. 2006. Wayne D Phillips. Title: HIV Prevention Research for Men who have Sex with Men: Methodologic Issues, Systematic Review and Meta-analysis. 2010 Rebecca Speckman. Title: Class Discovery: revisiting case definition. 2010 T. Christopher Bond, PhD. Title: Influenza Vaccination in a High-risk Population: An Evidence-Based Approach to Public Health. 2010 Andrea Winquist, MD. Title: Trends in in-hospital acute stroke care processes and stroke patient outcomes observed during operation of the Georgia Coverdell Acute Stroke Registry (GCASR). 2010 Rachel Patzer, MPH. Title: Determinants of Racial Disparities in Access to Renal Transplantation: from Dialysis Initiation to Transplant Referral, Evaluation, Waitlisting, and Transplant. (Candidacy 2010) Idris Guessous, MD Title: Chronic kidney disease, vitamin D and gene-environment interaction. (defense pending) Winn Cashion Title: Polypharmacy and Patterns of Exposure to Renal-Dosed Medications. (defense pending) 5 W.M. McClellan, Jr. -p. 6 - Bibliography: 1. McClellan WM, Schafer JA. Transport of the amino acid analogue 2-amino (2, 2, 1) heptane2-carboxylic acid by Ehrlich ascites tumor cell. Biochem. Biophys. Acta 1973; 311:462-475. 2. McClellan, WM. Jones, J. Prolonged blood pressure control in a rural outpatient hypertension clinic: A description of methodology and results. Am Journal of Rural Health 1980; 6:33-38. 3. McClellan, WM. Community hypertension control, the rural perspective. Journal of the South Carolina Medical Assoc 1980; 9:2-9. 4. McClellan, WM. The West Georgia Community Hypertension Control Program; a rural health alliance. In Workshops in primary Care. Steven Marlow and Martha McGowan, eds. The National Primary Care Associates, Waterville, ME., 1980. 5. McClellan, WM. Practical steps toward improving patient compliance with antihypertensive therapy. J Med Assoc Georgia 1981; 70: 357-360. 6. Chiapini, M., Henson, M.A., Wilber, J.A., McClellan, W.M. Statewide community high blood pressure control programs. J Med Assoc Georgia 1981; 70: 357-360. 7. McClellan, WM., Wilber, J.A., Hypertension Control in the Community. In Community Hypertension Control Programs in the U.S.: A decade’s experience. JB. Rosenfeld, DS. Silverburg and R. Viskoper, eds., John Libby, London, 1985. 8. McClellan, WM., Gilber, J.A., Hall, WD. Physician Hypertension Practice in Georgia-Results of the 1989 American Heart Association/Georgia Affiliate Physician Survey. J Med Assoc Georgia 1984; 73: 217-233. 9. McClellan, WM., Connel L. Improved Follow-up Care of the Hypertensive Patients by a Nurse Practitioner in a rural clinic. J Rural Health 1985; 1:34-41 10. McClellan WM., Owens S. The American Heart Association-Georgia Affiliate Hypertension Education Network for Physicians. J Med Assoc Georgia 1985; 74:151-163. 11. McClellan WM. The physician and patient education: A review. Patient Education and Counseling 1986; 74: 591-594. 12. McClellan WM., Hall, WD., Brogan D., Martinez B., Wilber JA. Isolated systolic hypertension: Declining prevalence in the elderly. Preventive Med 1987; 16: 686-695. 13. McClellan WM., Hall WD., Brogan D., Wilber JA. Continuity of Care: An important correlate of blood pressure control among aware hypertensive. Arch Intern Med 1988; 148:525-528. 14. McClellan WM., Tuttle E., Issa A. Racial differences in the incidence of hypertensive ESRD are not entirely explained by differences in the prevalence of hypertension. Am J Kidney Disease 1988; 12: 285-290. 15. McClellan WM., Neel J., Owen S. Correlates drug therapy of diastolic blood pressure between 80-89 mm Hg by physicians in the community. Am J of Hypertension 1989; 2:869871. 16. McClellan WM. The Epidemiology of end-stage renal disease in Georgia. J Med Assoc Georgia 1990; 79:153-156. 17. McClellan WM., Anson C., Birkeli K., Tuttle E. Functional status and quality of life: Predictors of early mortality among patients entering treatment for end-stage renal disease. J Clin Epid 1991; 44:83-89. 18. Soucie JM, Neylan JF, McClellan WM. Race and Sex Differences in the Identification of Candidates for Renal Transplantation. Am J Kidney Disease 1992; 19:414-419. 19. McClellan WM, Flanders WD, Gutman RA. Variable Mortality Rates among Dialysis Treatment Centers. Ann Intern Med 1992; 117: 332-336. 20. McClellan WM. The Study of Hypertensive end-stage renal disease (ESRD) in Blacks: The role of ESRD surveillance in the ESRD Networks. Am J Kidney Disease 1993; 21 (SUPP. 1):25-30. 6 W.M. McClellan, Jr. -p. 7 21. McClellan WM, Anson CA, Stanwyck DJ. Social Support and Subsequent Mortality among 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 7 patients with ESRD. J Am Soc Nephr 1993; 4:1028-1035. McClellan WM. The Epidemic of end-stage renal disease in the United States: A public health perspective on ESRD prevention. AKF Nephrology Newsletter 1993; 10:29-40. Gomez-Farias MA, McClellan WM, Soucie JM, Mitch WE. A prospective comparison of methods for determining if cardiovascular disease is a predictor of mortality in dialysis patients. Am J Kidney Disease 1994; 23:382-388. McClellan WM, Soucie JM. Facility Mortality Rates for New End-Stage Renal Disease Patients: Implications for Quality Improvement. Am J Kidney Diseases1994; 24:280-289. Soucie JM, Thun MJ, Coates RJ, McClellan WM, Austin H. Demographic and Geographic Variability of Kidney Stones In The U.S. Kidney Int 1994; 46:893-899. McClellan WM. Using continuous quality improvement to improve the care of patients receiving Epoetin Alfa. New Directions in Anemia 1994; 5:1-6. Farias, MG Soucie JM, McClellan WM, Mitch WE. Race and the risk of peritonitis: An analysis of factors associated with initial episode. Kid Intern 1994; 46:1392-1397. McClellan WM. Epidemic end-stage renal disease in the United States (Editorial). Artificial Organs 1994; 18:413-415. McClellan WM, Helgerson S, Frederick P, Wish J. Implementing the Health Care Quality Improvement Program in the Medicare End-Stage Renal Disease Program: A new era of quality improvement. Advances in Renal Replacement Therapy 1995; 2:89-95. McClellan WM, Frederick P, Helgerson S, Hayes R, Ballard D, McMullan M. A Health Care Quality Improvement Program for end-stage renal disease (ESRD). Health Care Financing Review, 1995: 16; 129-140. Barker-Cummings C, McClellan WM, Soucie JM, Krisher J. Racial disparities in peritoneal dialysis used by new end-stage renal disease patients. JAMA, 1995; 274:1858-62. Soucie JM, Coates RJ, McClellan WM, Austin H, Thun M. Risk factors associated with Prevalent Kidney Stones. American Journal of Epidemiology, 1996:143:487-95. McClellan WM, Wish J, Cangialose C. Epidemic end-stage renal disease and Nephrology Manpower Trends: Crisis or Opportunity? Seminars in Dialysis, 1995. Rocco M.V., Soucie JM., Reboussin D., McClellan WM. Risk factors for hospital utilization in chronic dialysis patients. J Am Soc Nephrol. 1996; 7:889-896. McClellan WM. Quality of patient care in the Medicare End-Stage Renal Disease (ESRD) Program: The basic and Implementation of the 1994-1997 ESRD Health Care Quality Improvement Program (HCQRP). Nephrology and Hypertension. 1996; 5;224-229.43 Freedman BI, Soucie JM; McClellan WM Family history of end-sage renal disease among incident dialysis patients J Am Soc Nephrol 1997:8:1942-45 McClellan WM., Knight D, Karp H, Brown WW. Early detection and treatment of renal disease in hospitalized Medicare patients: Important differences between practice and published guidelines. Am J Kidney Dis, 1997; 29:368-375. Helgerson SD, McClellan WM, Frederick PR, Beaver SK., Frankenfield DL, McMullan M. Improvement in adequacy of delivered dialysis for adult in-center hemodialysis patients in the United States, 1993 to 1995 Am J Kidney Dis, 1997; 29:851-861. Rocco MV, Flanigan MJ, Beaver S, Frederick P, Gentile DE, McClellan WM, Polder J, Prowant BF, Taylor L, Helgerson SD. Report from the 1995 Core Indicators for Peritoneal Dialysis Study Group. Am J Kidney Dis 1997; 30:165-173. Astin GT; Honig E; Shipp C; Moore B; McClellan W. Initial antibiotic management of community acquired pneumonia. J Med Assoc Ga 1997; 86:105-8 McClellan WM; Soucie JM; Krisher J; Caruana R; Haley W; Farmer C. Improving the care of patients treated with hemodialysis: a report from the Health Care Financing Administration's ESRD Core Indicators Project. Am J Kidney Dis 1998; 31(4):584-92 W.M. McClellan, Jr. -p. 8 42. McClellan WM, Soucie JM, Flanders WD. Mortality in end-stage renal disease (ESRD) is 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 8 associated with differences in physician supervision and adequacy of hemodialysis treatments. J Am Soc Nephrol 1998; 98:1940-1947. Mitch W, McClellan WM. Working patterns of nephrologists: Implications for nephrology training and manpower policies (with editorial comment). Am J Kidney Disease 1998; 32:551-556 McClellan WM, Frankenfield D, Frederick P, Rocco M, Flanders F, Helgerson SD. Can dialysis therapy be improved? A report from the ESRD Core Indicators Project. Am J Kidney Dis 1998; 31:584-592. McClellan WM, Frankenfield DL, Frederick PR, Flanders WD, Alfaro-Correa A, Rocco M, Helgerson SD Can dialysis therapy be improved? A report from the ESRD Core Indicators Project. Am J Kidney Dis. 1999; 34:1075-82. Bright RA, Torrence ME, Daley WR, McClellan WM. Preliminary survey of the occurrence of anaphlactoid reactions during hemodialysis (Letter). Nephrology and Transplantation 1999; 14:779 Frankenfield D, McClellan WM, Helgerson SD, Lowrie E, Rocco M, Owen W. Relationship between urea reduction ratio (URR), demographic characteristics and body weight for patients in the 1996 ESRD Core Indicators Project. Am J Kid Dis 1999; 33:584-591. McClellan WM, Rocco MV, Flanders WD. Epidemiology and the study of critical nutritional issues in the care of the dialysis patient: Report of the Epidemiology Working Group. J Renal Nutrition (invited commentary) 1999; 9:133-137. Bailie GR, Frankenfield DL, Prowant BF, McClellan WM, Rocco MV. Erythropoietin and iron use in peritoneal dialysis patients. Report from the 1997 HCFA End-Stage Renal Disease Core Indicators Project. Am J Kidney Dis. 1999; 33:11877-1180. Frankenfield DL, Rocco MV, Pugh J, McClellan WM, Owen WF. Race/Ethnic analysis of selected intermediate outcomes for in-center hemodialysis ESRD Patients: Results from the 1997 ESRD Core Indicators Project. Am J Kidney Dis 1999; 34:721-30 Freedman BI, Soucie JM, Chapman A, Krisher J, McClellan WM. Racial variation in autosomal dominant polycystic kidney disease. Am J Kidney Dis 2000; 35:35-9 Flanders WD, Tucker G, Krishnadasan A, Martin D, Honig E, McClellan WM. Validation of the pneumonia severity index. Importance of study-specific recalibration. J Gen Intern Med. 1999;14:333-40. McClellan WM, Krisher JO. Collecting and using patient and treatment center data to improve care: Adequacy of hemodialysis and end-stage renal disease surveillance. Kidney Intern 2000; 57 (suppl 74): s7-s13. Luthi Jean-Christophe, McClellan WM, Fitzgerald D, Herrin J, Abrams F, Krumholz H, Bratzler D, Elward K, Hayes R, Ballard D. Hospital-to-hospital variations in the quality of care of heart failure among hospitalized Medicare beneficiaries. Eff Clin Pract 2000; 3:6977. Kutner NG, Zhang R, McClellan WM. Patient-reported quality of life in dialysis treatment: Effects associated with usual physician activity Nephrol Nurs J. 2000; 27:357-67; discussion 368, 424. Rocco M, Soucie JM, Pastan S, McClellan WM. Peritoneal dialysis adequacy and risk of death. Kidney Int. 2000; 58:446-57. Rocco MV, Frankenfield DL, Frederick PR, Pugh J, McClellan WM, Owen WF. Intermediate outcomes by race and ethnicity in peritoneal dialysis patients: Results from the 1997 ESRD Core Indicators Project. Perit Dial Int. 2000; 20:328-35. Kohler KA, McClellan WM, Ziemer DC, Kleinbaum DG, Boring JR. Microalbuminuria in urban African-Americans with type 2 diabetes. Possible link to Insulin resistance syndrome? Am J Kidney Dis. 2000; 36:903-913. W.M. McClellan, Jr. -p. 9 59. McClellan WM, Frankenfield DL, Wish JB, Rocco MV, Owen WF. Subcutaneous and 60. 61. 62. 63. 64. 65. 66. 67. 68. 69. 70. intravenous erythropoietin use among adult hemodialysis patients in the US in 1997: Results from the ESRD Core Indicators Project. Am J Kidney Dis. 2001; 37:E36. McClellan WM, Goldman RS. Continuous quality improvement in dialysis units: Basic tools. Adv Ren Replace Ther. 2001 Apr; 8(2):95-103. Freedman BI, Soucie JM, Kenderes B, Krisher J, Garrett LE, Caruana RJ, McClellan WM. Family history of end-stage renal disease does not predict dialytic survival. Am J Kidney Dis 2001; 38:547-552. Ramirez SP, Hsu SI, McClellan W. Low body weight is a risk factor for proteinuria in multiracial Southeast Asian pediatric population. Am J Kidney Dis. 2001; 38:1045-54. Rocco MV, Bedinger MR, Milam R, Greer JW, McClellan WM, Frankenfield DL. Duration of dialysis and its relationship to dialysis adequacy, anemia management, and serum albumin level. Am J Kidney Dis. 2001; 38:813-23. Kohler KA, McClellan WM, Ziemer DC, Kleinbaum DG, Boring JR. Smoking and Microalbuminuria: A case-control study in African-Americans with type 2 diabetes. Diabetes Care. 2002; 25:243-245. Rossert JA, McClellan WM, Roger SD, Verbeelen DL, Horl WH. Contribution of anaemia to progression of renal disease: a debate. Nephrol Dial Transplant. 2002; 17 Suppl 1:60-66. Rossert J, McClellan WM, Roger SD, Verbeelen DL. Epoetin treatment: what are the arguments to expect a beneficial effect on renal disease progression? Nephrol Dial Transplant. 2002; 17:359-62. Luthi JC, McClellan WM, Fitzgerald D, Krumholz HM, Delaney RJ, Bratzler DW, Elward K, Cangialos CB, BallardDJ. Mortality associated with the quality of care of patients hospitalized with congestive heart failure. Int J Qual Health Care. 2002; 14:15-24. Kutner NG, Zhang R, McClellan WM, Cole SA. Psychosocial predictors of non-compliance in haemodialysis and peritoneal dialysis patients. Nephrol Dial Transplant. 2002; 17:93-99. Eggers PW, Frankenfield DL, Greer JW, McClellan W, Owen WF Jr, Rocco MV. Comparison of mortality and intermediate outcomes between medicare dialysis patients in HMO and fee for service. Am J Kidney Dis. 2002; 39:796-804. Hoehner CM, Greenlund KJ, Rith-Najarian S, Casper ML, McClellan WM. Association of the Insulin Resistance Syndrome and Microalbuminuria among Nondiabetic Native Americans. The Inter-Tribal Heart Project. J Am Soc Nephrol. 2002; 13:1626-34. 71. Pastan S, Soucie JM, McClellan WM. Vascular access and increased risk of death among hemodialysis patients. Kidney Int. 2002; 62:620-6. 72. McClellan WM, Flanders WD, Langston RD, Jurkovitz C, Presley R. Anemia and Renal 73. 74. 75. 76. 9 Insufficiency Are Independent Risk Factors for Death among Patients with Congestive Heart Failure Admitted to Community Hospitals: A Population-Based Study. J Am Soc Nephrol. 2002; 13:1928-36. Fink JC, Zhan M, Blahut SA, Soucie M, McClellan WM. Measuring the efficacy of a quality improvement program in dialysis adequacy with changes in center effects. J Am Soc Nephrol. 2002; 13:2338-44. Ramirez SP, McClellan W, Port FK, Hsu SI. Risk factors for proteinuria in a large, multiracial, southeast asian population. J Am Soc Nephrol. 2002; 13:1907-17. Jurkovitz C, Franch H, Shoham D, Bellanger J, McClellan WM. Abnormal renal function and prevalence of risk factors for renal disease among family members of patients treated for renal disease. Am J Kidney Dis. 2002; 40:1173-8. Luthi JC, McClellan W, Flanders D, Pitts S, Burnand B. Quality of health care surveillance systems: review and implementation in the Swiss setting. Swiss Med Wkly. 2002; 132:461469. W.M. McClellan, Jr. -p. 10 77. McClellan W. As to diseases, make a habit of two things - to help, or at least do no harm. J Am 78. 79. 80. 81. 82. 83. 84. 85. 86. 87. 88. 89. 90. 91. 92. 10 Soc Nephrol. 2002; 13:2817-9. Phillips LS, Hertzberg VS, Cook CB, El-Kebbi IM, Gallina DL, Ziemer DC, Miller CD, Doyle JP, Barnes CS, Slocum W, Lyles RH, Hayes RP, Thompson DN, Ballard DJ, McClellan WM, Branch WT Jr. The Improving Primary Care of African Americans with Diabetes (IPCAAD) project: rationale and design. Control Clin Trials. 2002; 23:554-69. Hayes PR, Baker DW, Luthi JC, Baggett RL, McClellan WM, Fitzgerald D, Abrams RL, Bratzler D, BallardDJ. The effect of external feedback on the management of Medicare in-patients with congestive heart failure. Am J Medical Quality: 2002; 17; 225-236. Reddan DN, Frankenfield DL, Klassen PS, Coladonato JA, Szczech L, Johnson CA, Besarab A, Rocco M, McClellan W, Wish J, Owen Jr WF, Jr.: Regional variability in Anaemia management and haemoglobin in the US. Nephrol Dial Transplant 18:147-152., 2003 Frankenfield DL, Rocco MV, Roman SH, McClellan WM. Survival advantage for adult Hispanic hemodialysis patients? Findings from the end-stage renal disease clinical performance measures project. J Am Soc Nephrol. 2003; 14:180-6 St. Peter WL, Schoolwerth AC, McGowan T, McClellan WM. Chronic Kidney Disease Issues and Establishing Programs and Clinics For Improved Patient Outcomes. Am J Kidney Dis. 2003; 41:903-24. Powell KE, Diseker RA, Presley RJ, Tolsma D, Harris S, Viel K, Conn DL, McClellan WM. Administrative data as a tool for arthritis surveillance: estimating prevalence and utilization of services. J Public Health Manag Pract. 2003; 9:291-8. McClellan WM, Ramirez SP, Jurkovitz C. Screening for chronic kidney disease: unresolved issues. J Am Soc Nephrol. 2003 Jul;14(7 Suppl 2):S81-7 McClellan WM, Flanders WD. Risk factors for progressive chronic kidney disease. J Am Soc Nephrol. 2003 Jul;14(7 Suppl 2):S65-70. Frankenfield DL, Ramirez SPB, McClellan WM, Kimmel PL, Rocco MV, Frederick PR, Besarab A, Agodoa LT, Owen WF Jr. Differences in Intermediate Outcomes for Asian and non-Asian Adult Hemodialysis Patients: Findings from the End Stage Renal Disease (ESRD) Clinical Performance Measures (CPM) Project. Kidney Int. 2003; 64:623-31. Langston RD, Presley R, Flanders WD, McClellan WM. Renal insufficiency and anemia are independent risk factors for death among patients with acute myocardial infarction. Kidney Int. 2003; 64:1398-405. Sugarman JR, Frederick PR, Frankenfield DL, Owen WF Jr, McClellan WM; Dialysis Outcomes Quality Initiative Clinical Practice Guidelines. Developing clinical performance measures based on the Dialysis Outcomes Quality Initiative Clinical Practice Guidelines: process, outcomes, and implications. Am J Kidney Dis. 2003; 42:806-12. Luthi JC, Lund MJ, Sampietro-Colom L, Kleinbaum DG, Ballard DJ, McClellan WM. Readmissions and the quality of care in patients hospitalized with heart failure. Int J Qual Health Care. 2003; 15:413-21. Jurkovitz CT; Abramson J; Vaccarino LV; Weintraub WS; McClellan WM. The Association of high serum creatinine and Anemia Increases the Risk of Cardiovascular Events: Results from the Prospective Community-Based Atherosclerosis Risk in Communities (ARIC) Study. J Am Soc Nephrol. 2003; 14:2919-25. Abramson JL, Jurkovitz CT, Vaccarino V, McClellan, W Renal Insufficiency, Anemia, and Risk of Incident Stroke in a Middle-Aged, Community-Based Population: The ARIC Study. (Kidney Int. 2003; 64:610-5. McClellan WM, Frankenfield DL, Frederick PR, Helgerson SD, Wish JB, Sugarman JR. Improving the Care of ESRD Patients: A Successful Application of the Medicare Health Care Quality Improvement Program. Health Care Financ Rev. 2003; 24:89-100. W.M. McClellan, Jr. -p. 11 93. McClellan WM, Ziemer D, Millman L, Presley R, Couzins J, Flanders WD. Improving diabetes care by primary care physicians: Results of a group-randomized intervention. J Clin Epidemiol. 2003; 56:1210-7. 94. Luthi JC, Burnand B, McClellan WM, Pitts SR, Flanders WD. Is readmission to hospital an indicator of poor process of care for patients with heart failure? Qual Saf Health Care. 2004; 13:46-51. 95. McClellan WM, Hodgin E, Pastan S, McAdams L, Soucie M. A Randomized Evaluation of Two Health Care Quality Improvement Program (HCQIP) Interventions to Improve the Adequacy of Hemodialysis Care of ESRD Patients: Feedback Alone versus Intensive Intervention. J Am Soc Nephrol. 2004; 15:754-60. 96. Ritz E, McClellan WM. Overview: increased cardiovascular risk in patients with minor renal dysfunction: an emerging issue with far-reaching consequences. J Am Soc Nephrol. 2004; 15:513-6. 97. McClellan WM, Langston RD, Presley R. Medicare patients with cardiovascular disease have a high prevalence of chronic kidney disease and a high rate of progression to end-stage renal disease. J Am Soc Nephrol. 2004; 15:1912-9. 98. Luthi JC, Flanders WD, Pitts SR, Burnand B, McClellan WM. Outcomes and the quality of care for patients hospitalized with heart failure. Int J Qual Health Care. 2004; 16:201-10. 99. Frankenfield DL, Roman SH, Rocco MV, Bedinger MR, McClellan WM. Disparity in outcomes for adult Native American hemodialysis patients? Findings from the ESRD Clinical Performance Measures Project, 1996 to 1999. Kidney Int. 2004; 65:1426-34. 100. Vupputuri S, Soucie JM, McClellan W, Sandler DP. History of kidney stones as a possible risk factor for chronic kidney disease. Ann Epidemiol. 2004; 14:222-8. 101. Speckman RA, Frankenfield DL, Roman SH, Eggers PW, Bedinger MR, Rocco MV, McClellan WM. Diabetes is the strongest risk factor for lower-extremity amputation in new hemodialysis patients. 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McClellan WM, Warnock DG, Judd S, Muntner P, Patzer RE, Bradbury BD, McClure LA, Newsome BB, Howard G. Association of family history of ESRD, prevalent albuminuria, and reduced GFR with incident ESRD. Am J Kidney Dis. 2012; 59(1):25-31. PubMed PMID: 22078058. 202. Parikh DS, Inrig JK, Kipp A, Szczech LA, McClellan W, Patel UD. Veterans more likely to start hemodialysis with an arteriovenous fistula. Semin Dial. 2011 Sep-Oct;24(5):570-5. PubMed PMID: 21913987. 203. Bowling CB, Inker LA, Gutiérrez OM, Allman RM, Warnock DG, McClellan W, Muntner P. Age-specific associations of reduced estimated glomerular filtration rate with concurrent chronic kidney disease complications. Clin J Am Soc Nephrol. 2011 Dec;6(12):2822-8. PubMed PMID: 22034504; PubMed Central PMCID: PMC3255373. 204. Patzer RE, Perryman JP, Pastan S, Amaral S, Gazmararian JA, Klein M, Kutner N, McClellan WM. Impact of a Patient Education Program on Disparities in Kidney Transplant Evaluation. Clin J Am Soc Nephrol. 2012 Feb 16. [Epub ahead of print] PubMed PMID: 22344515. 205. Chang TI, Gao L, Brown TM, Safford MM, Judd SE, McClellan WM, Limdi NA, Muntner P, Winkelmayer WC. Use of Secondary Prevention Medications among Adults with Reduced Kidney Function. Clin J Am Soc Nephrol. 2012 Feb 16. [Epub ahead of print] PubMed PMID: 22344513. 206. Lilly MP, Lynch JR, Wish JB, Huff ED, Chen SC, Armistead NC, McClellan WM. Prevalence of Arteriovenous Fistulas in Incident Hemodialysis Patients: Correlation With Patient Factors That May Be Associated With Maturation Failure. Am J Kidney Dis. 2012 Feb 16. [Epub ahead of print] PubMed PMID: 22342212. 207. Rizk DV, Gutierrez O, Levitan EB, McClellan WM, Safford M, Soliman EZ, Warnock DG, Muntner P. Prevalence and prognosis of unrecognized myocardial infarctions in chronic kidney disease. Nephrol Dial Transplant. 2011 Dec 13. [Epub ahead of print] PubMed PMID: 22167594. 208. Binder EF, White HK, Resnick B, McClellan WM, Lei L, Ouslander JG. A prospective study of outcomes of nursing home residents with chronic kidney disease with and without anemia. J Am Geriatr Soc. 2012; 60:877-83. PubMed PMID: 22568452. 209. Amaral S, Patzer RE, Kutner N, McClellan W. Racial disparities in access to pediatric kidney transplantation since share 35. J Am Soc Nephrol. 2012; 23:1069-77. PubMed PMID: 22539831. 210. McClellan AC, Plantinga L, McClellan WM. Epidemiology, geography and chronic kidney disease. Curr Opin Nephrol Hypertens. 2012; 21:323-8. PubMed PMID: 22388555. 211. Bell EK, Gao L, Judd S, Glasser SP, McClellan W, Gutiérrez OM, Safford M, Lackland DT, Warnock DG, Muntner P. Blood pressure indexes and end-stage renal disease risk in adults with chronic kidney disease. Am J Hypertens. 2012; 25:789-96. PubMed PMID:22573012. 212. Mohan S, Tanriover B, Ali N, Crew RJ, Dube GK, Radhakrishnan J, Hardy MA, Ratner LE, McClellan W, Cohen D. Availability, Utilization and Outcomes of Deceased Diabetic Donor Kidneys; Analysis Based on the UNOS Registry. Am JTransplant. 2012; 12:2098-105. PubMed PMID: 22758926. 213. Patzer RE, McClellan WM. Influence of race, ethnicity and socioeconomic status on kidney disease. Nat Rev Nephrol. 2012; 8:533-41. PubMed PMID: 22735764. 200. 18 W.M. McClellan, Jr. -p. 19 - Crews DC, McClellan WM, Shoham DA, Gao L, Warnock DG, Judd S, Muntner P, Miller ER, Powe NR. Low Income and Albuminuria Among REGARDS (Reasons for Geographic and Racial Differences in Stroke) Study Participants. Am J Kidney Dis. 2012 Jun 11.PubMed PMID: 22694949. 215. Bond TC, Spaulding AC, Krisher J, McClellan W. Mortality of Dialysis Patients According to Influenza and Pneumococcal Vaccination Status. Am J Kidney Dis. 2012 Jun 11. PubMed PMID: 22694948. 216. Tanner RM, Gutiérrez OM, Judd S, McClellan W, Bowling CB, Bradbury BD, Safford MM, Cushman M, Warnock D, Muntner P. Geographic Variation in CKD Prevalence and ESRD Incidence in the United States: Results From the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Am J Kidney Dis. 2012 Dec 7. PubMed PMID: 23228944. 217. Beaubrun AC, Kanda E, Bond TC, McClellan WM. Form CMS-2728 Data Versus Erythropoietin Claims Data: Implications for Quality of Care Studies. Ren Fail. 2012 Dec 11. [Epub ahead of print] PubMed PMID: 23227806. 218. Erickson KF, Lea J, McClellan WM. Interaction between GFR and Risk Factors for Morbidity and Mortality in African Americans with CKD. Clin J Am Soc Nephrol. 2013 Jan;8(1):75-81. doi: 10.2215/CJN.03340412. Epub 2012 Oct 18. PubMed PMID: 23085727; PubMed Central PMCID: PMC3531654. 219. Gutiérrez OM, Judd SE, Muntner P, Rizk DV, McClellan WM, Safford MM, Cushman M, Kissela BM, Howard VJ, Warnock DG. Racial differences in albuminuria, kidney function, and risk of stroke. Neurology. 2012 Oct 16;79(16):1686-92. doi: 10.1212/WNL.0b013e31826e9af8. Epub 2012 Sep 19. PubMed PMID: 22993285; PubMed Central PMCID: PMC3468778. 220. McClellan AC, Luthi JC, Lynch JR, Soucie JM, Kulkarni R, Guasch A, Huff ED, Gilbertson D, McClellan WM, DeBaun MR. High one year mortality in adults with sickle cell disease and end-stage renal disease. Br J Haematol. 2012 Nov;159(3):360- . doi: 10.1111/bjh.12024. Epub 2012 Sep 12. PubMed PMID: 22967259. 221. Tuot DS, Plantinga LC, Judd SE, Muntner P, Hsu CY, Warnock DG, Gutiérrez OM, Safford M, Powe NR, McClellan WM. Healthy Behaviors, Risk Factor Control and Awareness of Chronic Kidney Disease. Am J Nephrol. 2013 Jan 31;37(2):135-143. PubMed PMID: 23392070. 222. McClellan WM, McClellan CB. Poverty and mortality in hemodialysis patients. J Am Soc Nephrol. 2013 Feb;24(2):165-7. doi: 10.1681/ASN.2012121176. PubMed PMID: 23334391. 223. Bowling CB, Muntner P, Bradbury BD, Kilpatrick RD, Isitt JJ, Warriner AH, Curtis JR, Judd S, Brown CJ, Allman RM, Warnock DG, McClellan W. Low Hemoglobin Levels and Recurrent Falls in U.S. Men and Women: Prospective Findings from the REasons for Geographic And Racial Differences in Stroke (REGARDS) Cohort. Am JMed Sci. 2013 Jan 16. PubMed PMID: 23328832. 224. Tanner RM, Gutiérrez OM, Judd S, McClellan W, Bowling CB, Bradbury BD, Safford MM, Cushman M, Warnock D, Muntner P. Geographic Variation in CKD Prevalence and ESRD Incidence in the United States: Results From the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Am J Kidney Dis. 2013; 61(3):395-403. PMID:23228944. 225. Kulshreshtha A, Vaccarino V, Judd SE, Howard VJ, McClellan WM, Muntner P, Hong Y, Safford MM, Goyal A, Cushman M. Life's Simple 7 and Risk of Incident Stroke: The Reasons for Geographic and Racial Differences in Stroke Study. Stroke. 2013 ;44(7):1909-14. PMID: 23743971. 214. 19 W.M. McClellan, Jr. -p. 20 - Patzer RE, Sayed BA, Kutner N, McClellan WM, Amaral S. Racial and ethnic differences in pediatric access to preemptive kidney transplantation in the United States. Am J Transplant. 2013; 13(7):1769-81. PMID: 23731389. 227. Plantinga L, Howard VJ, Judd S, Muntner P, Tanner R, Rizk D, Lackland DT, Warnock DG, Howard G, McClellan WM. Association of duration of residence in the southeastern United States with chronic kidney disease may differ by race: the REasons for Geographic and Racial Differences in Stroke (REGARDS) cohort study. Int J Health Geogr. 2013;12: 17. PMCID: PMC3606831. 228. Muntner P, Judd SE, Gao L, Gutiérrez OM, Rizk DV, McClellan W, Cushman M, Warnock DG. Cardiovascular Risk Factors in CKD Associate with Both ESRD and Mortality. J Am Soc Nephrol. 2013 Jun;24(7):1159-65. PMCID: PMC3699822. 229. Bulka C, Nastoupil LJ, McClellan W, Ambinder A, Phillips A, Ward K, Bayakly AR, Switchenko JM, Waller L, Flowers CR. Residence proximity to benzene release sites is associated with increased incidence of non-Hodgkin lymphoma. Cancer. 2013 Jul 29. doi: 10.1002/cncr.28083. [Epub ahead of print] PubMed PMID:23896932. 226. Books and chapters. William M. McClellan, Anton C. Schoolwerth, Todd Gehr. Clinical Management of Chronic Kidney Disease. Professional Communications; Caddo, OK. 2006 Franch, Harold; McClellan, William; and Mitch, William. Chronic kidney Disease: Pathophysiology and influence of dietary protein. In. Robert J. Alpern and Steven C. Hebert. The Kidney: Physiology and Pathophysiology, 4th edition, 2007 Masud,Tahsin and McClellan, William. The Heart and Kidney Disease In. Valentin Fuster, R. Wayne Alexander, Robert A. O'Rourke, Robert Roberts, Spencer B. King, Eric N. Prystowsky, Ira Nash. Hurst's The Heart, 11th Edition, 2008; 12th Edition, in press William M. McClellan and Friedrich K. Port. Epidemiology of chronic kidney disease. In Donald A. Molony, M.D., Jonathan C. Craig. Evidence-Based Nephrology, 2008. 20