Humoral (IgE and IgG) Immune Response Dependent Signaling in Human Allergic Disease 18th Annual Johns Hopkins Asthma and Allergy Center Symposium Friday, November 21, 2008 TO REGISTER: By email: ndietz@jhmi.edu By phone: 410-550-2052 7:30 a.m.- 8:20 a.m. 8:20 a.m. - 8;30 a.m. Registration and Continental Breakfast Welcome: 8:30 a.m. – 9:15 a.m. S.G.O. Johansson, M.D. (Sweden) IgE and IgE-Antibody in Allergy (Clinical Significance of the Ratio of Circulating Specific IgE to Total IgE) 9:15 a.m. – 10:00 a.m. Rob Aalberse, Ph.D. (Netherlands) IgG Antibodies as Modulators of Allergic Disease (Protective properties of IgG4; Significance of Naturally Occurring IgG anti-IgE responses) 10:00 a.m. – 10:30 a.m. Coffee Break 10:30 a.m. – 11:15 a.m. Rudolph Valenta, M.D. (Vienna) Molecular-Chip and Component Based Diagnosis and Treatment of Allergic Disease (Clinical importance of recombinant allergen specific Immune response profiles) 11:15 a.m.- 12:00 noon Hannah Gould, Ph.D. (England) Network of IgE and IgG Receptors in Allergic Disease. (Molecular Signaling with Monomeric IgE; Focus on High affinity IgE receptor) 12 noon-1:30 pm Lunch 1:30 p.m. – 2:15 p.m. Dan Conrad, Ph.D. (USA) IgE Immune Responses Via the Low Affinity IgE Receptor 2:15 p.m. – 3:00 p.m. Dean Metcalfe, M.D. (USA) The FcRI-KIT Axis: Relevance to Clinical Disorders of Mast Cell Function” Coffee and Pastry Break 3:00 p.m. – 3:15 p.m. 3:15 p.m. – 4:00 p.m. Andy Saxon, MD. (USA) Fc-gamma/Fc-epsilon Targeting Molecules As Therapeutics for Allergic Disease Talks will be ~35-40 minutes in length followed by ~10 minutes of discussion TO REGISTER: By email: ndietz@jhmi.edu By phone: 410-550-2052