PATHOLOGY - EXAM QUESTIONS I. General Pathology 1. History of pathology (Morgagni, Rokitansky, Virchow, PurkynÄ›, Treitz, Lambl, Prowazek) 2. Necropsy; surgical pathology (methods; principles) 3. Etiology; pathogenesis (causes of cell injury) 4. Death and postmortal changes 5. Necrosis; gangrene 6. Atrophy 7. Amyloidosis 8. Fatty change (steatosis) 9. Disorders of lipid metabolism 10. Disorders of carbohydrates metabolism (diabetes mellitus; glycogenoses) 11. Calcification 12. Crystals 13. Lithiasis 14. Endogenous pigments 15. Hematogenous pigments 16. Jaundice 17. Exogenous pigments 18. Cysts 19. Adaptation (hypertrophy; hyperplasia) 20. Repair (regeneration; reparation) 21. Inflammation (definition; classification; clinical manifestations) 22. Acute inflammation 23. Chronic inflammation 24. Serous and fibrinous inflammation 25. Suppurative inflammation 26. Pseudomembranous and gangrenous inflammation 27. Specific (granulomatous) inflammation 28. Genetic diseases 29. Streptococcal infections 30. Staphylococcal infections 31. Pneumococcal and neisserial infections 32. Infections by E. coli and Salmonellae 33. Infections by Pasteurellae (Yersiniae) and Brucellae 34. Spirochetal diseases 35. Mycotic diseases 36. Rickettsial and Chlamydial diseases 37. Mycobacterioses (tbc; leprosy) 38. Viral infections - general features; review 39. Varicella - herpes zoster 40. Herpes simplex 41. Influenza 42. Infectious mononucleosis 43. Measles; rubella 44. Mumps; cytomegalovirus 45. Acute hepatitis 46. Chronic hepatitis 47. Diseases caused by parasites 48. Sexually transmitted diseases 49. Environmental diseases - review 50. Adverse effects of smoking 51. Pneumoconioses 52. Injury by therapeutic agents (analgetics, barbiturates, estrogens, antineoplastic drugs, antibiotics, immunosuppressives) 53. Adverse effects of alcohol (acute; chronic) 54. Injury by physical agents (mechanical; thermal; radiation) 55. Nutritional diseases; malnutrition 56. Vitamin deficiencies 57. Obesity-its complications 58. Diet and cancer 59. Disorders of the immune system; transplant rejection 60. Autoimmune diseases 61. Immunodeficiency diseases II. Cardiovascular system l. Congestive heart failure 2. Hypertrophy, dilatation and decompensation of the heart 3. Organ lesions induced by failing circulation 4. Causes of congestive failure 5. Left - sided heart failure 6. Right - sided heart failure 7. Shock 8. Edema;dehydration (formation and drainage of interstitial fluid) 9. Local disorders of blood flow - review 10. Thrombosis 11. DIC - syndrome 12. Embolism 13. Metastasis 14. Hyperemia 15. Ischemia 16. Infarction - generally 17. Hemorrhage - generally 18. Atherosclerosis - review 19. Atherosclerosis - risk factors 20. Atherosclerosis - morphology (gross; histology) 21. Atherosclerosis - pathogenesis 22. Polyarteritis nodosa and related entities 23. Granulomatous arteritis 24. Thrombangiitis obliterans (Buerger) 25. Raynaud°s disease 26. Arterial aneurysms - review 27. Aortic aneurysms 28. Dissecting aneurysm 29. Venous disorders 30. Lymphatic disorders 31. Tumors of vessels 32. Ischemic heart disease - review 33. Coronary artery atherosclerosis 34. Angina pectoris 35. Sudden death 36. Myocardial infarction 37. Morphologic complications of myocardial infarcion 38. Chronic ischemic heart disease 39. Hypertensive heart disease 40. Rheumatic fever and rheumatic heart disease 41. Chronic rheumatic heart disease 42. Congenital heart disease 43. Infective endocarditis 44. Cor pulmonale 45. Pericardial diseases 46. Myocarditis 47. Cardiomyopathy 48. Heart diseases in the elderly (aortic stenosis; mitral annular calcification; amyloidosis) 49. Heart tumors 50. Nonbacterial thrombotic endocarditis 51. Hypertension 52. Calcification in the heart 53. Mitral stenosis 54. Arteriosclerosis III. Oncology 1. Tumors generally (definition; classification) 2. Metaplasia; dysplasia 3. Pseudotumors (cysts; hamartoma; hyperplasia) 4. Characteristics of benign and malignant neoplasms 5. Tumor metastasis 6. Granding and staging of cancer 7. Benign mesenchymal tumors 8. Malignant mesenchymal tumors 9. Benign epithelial tumors 10. Malignant epithelial tumors 11. Carcinogenesis (etiology of cancer) 12. Effects of tumors on host (benign vs. malignant) 13. Paraneoplastic syndromes 14. Geographic factors in occurrence of neoplasms 15. Precancerous lesions 16. Non-Hodgkin°s lymphomas 17. Hodgkin°s disease 18. Acute leukemias 19. Chronic leukemias 20. Myeloproliferative disorders 21. Plasma cell dyscrasias 22. Histiocytoses 23. Storage diseases 24. Tumors of the respiratory system - review 25. Bronchogenic carcinoma 26. Mesothelioma 27. Tumors of the oral cavity and nasopharynx 28. Salivary gland tumors 29. Esophageal tumors 30. Gastric tumors 31. Small intestine tumors 32. Large intestine tumors 33. Liver tumors 34. Biliary tract tumors 35. Exocrine pancreas tumors 36. Endocrine pancreas tumors 37. Kidney tumors 38. Tumors of the urinary collecting system 39. Testicular tumors 40. Carcinoma of the prostate 41. Tumors of the uterine cervix 42. Tumors of endometrium 43. Tumors of myometrium 44. Tumors of the ovary 45. Trophoblastic disease 46. Tumors of the breast - review 47. Carcinoma of the breast 48. Endocrine gland tumors 49. Bone tumors 50. Synovial, skeletal muscle and muscle sheath tumors 51. Soft tissue tumors 52. Brain tumors 53. Peripheral nerve tumors 54. Skin tumors (epidermoid Ca; basal cell Ca) 55. Pigmented nevi; melanoma 56. Mixed tumors; teratomas; tumor multiplicity IV. Organ pathology 1. Posthemorrhagic and hemolytic anemias 2. Anemias of diminished erythropoiesis; pernicious anemia 3. Polycythemia 4. Bleeding disorders 5. Lymphnode pathology - review 6. Spleen pathology - review 7. Thymus pathology - review 8. Pulmonary thromboembolism 9. Pulmonary hypertension 10. Respiratory distress syndrome 11. Sudden infant death syndrome 12. Chronic bronchitis 13. Lung emphysema 14. Bronchial asthma 15. Bronchiectasis 16. Pulmonary infections - review 17. Lobar pneumonia 18. Bronchopneumonia 19. Lung tuberculosis 20. Sarcoidosis 21. Pleural lesions - review 22. Lesions of the upper respiratory tract 23. Lesions of the oral cavity 24. Salivary gland diseases 25. Esophageal lesions 26. Gastric lesions - review 27. Gastritis 28. Peptic ulcer 29. Small bowel lesions - review 30. Crohn°s disease 31. Malabsorption syndrome 32. Small bowel obstruction 33. Large bowel lesions - review 34. Hirschprung°s disease 35. Enterocolitis 36. Lesions of the appendix 37. Lesions of the peritoneum - review 38. Herniae 39. Lesions of the liver - review 40. Hepatic failure; jaundice 41. Viral hepatitis 42. Liver cirrhosis 43. Alcoholic liver disease 44. Hemochromatosis 45. Lesions of the gallbladder and bile ducts 46. Lesions of the pancreas - review 47. Renal failure; uremia 48. The nephrotic syndrome 49. The nephritic syndrome 50. Pyelonephritis 51. Acute tubular necrosis 52. Vascular lesions of the kidney; nephrosclerosis 53. Malformations and cysts of the kidney 54. Renal stones 55. Kidney in diabetes mellitus 56. Lesions of the male genital system - review 57. Venereal diseases 58. Lesions of the vulva, vagina and cervix 59. Lesions of the uterine body (except tumors) 60. Lesions of fallopian tubes 61. Diseases of pregnancy 62. Pathology of the neonate 63. Lesions of the breast (except tumors) 64. Lesions of the pituitary gland 65. Lesions of the thyroid gland and parathyroid glands 66. Lesions of the adrenals 67. Diabetes mellitus 68. Lesions of the bones - review 69. Lesions of the joints - review 70. Lesions of skeletal muscle - review 71. Systemic lupus erythematosus 72. Rheumatoid arthritis 73. Systemic sclerosis; polymyositis 74. AIDS 75. Meningitis 76. Encephalitis 77. Vascular disease of the brain 78. Intracranial hemorrhage 79. Cerebral trauma 80. Degenerative and demyelinating diseases of the brain