PUBLICATIONS
1. Mukherjee, C. and Biehl, Ed, “An Efficient Synthesis of Benzene Fused Six-Mmembered,
Seven-membered, and Eight Membered Rings Containing Nitrogen and Sulfur by Benzyne
Ring Closure reaction.” Heterocycles, (2004), 63, 2102-2110.
2. Sathunuru, R. and Biehl, Ed, “Facile Synthesis of 4H-Naphtho[2,3-e] Derivatives of 1,3Thiazines, 1,3-Selenazines and Naphtho[2’,3’:4,5] Derivatives of Seleno[2,3-b]pyridines and
thieno[2,3-b]pyridines by the Reaction of Thiazadiens, Selenoazadiens, and Barton Selenium
and Sulfur Esters with 2,3-Didehydronaphthalene” ARKIVOC, (2004), (i) 346-356.
3. Kamila, S. and Biehl, Ed, “ Reaction of 1,3-Dihydroindole-2-thiones with Certain
Dienophiles: Preparation of Benzothiopyrano[2.3-b]indoles. Heterocycles, (2004), 63, 23042316.
3. Rao, U. N., Maguire, J. A. and Biehl, Ed, “Effect of Substituents and Benzyne Generating
Bases on the Orientation to and Reactivity of Haloarynes” ARKIVOC, (2004), (i) 88-100.
4. Kamili, Sukanta and Biehl, Edward R., Heterocycles, “New Synthesis of 3HBenzo[b]thiophen-2-one.” Heterocycles, (2004), 63, 1813-1819.
5. Sathururu, Ramadas and Biehl, Ed, “Nitration of Certain Hydroxy Derivatives of
HeterocyclesUSing CAN”, ARKIVOC, (2004), (i) 202-212.
6.
Sathunuru, Ramadas and Biehl, Ed, “Novel and Regioselective Synthesis of 7,4’-dihydroxy4-phenylchroman-2-ones.” ARKIVOC, (2004), (i) 138-145.
7. Rao, U. Narashima and Biehl, Ed, “Facile Synthesis of Facile Synthesis of 4H-1,3Benzoselenazines by the Aryne Reaction:, Heterocycles, (2004), 63, 1067.
8. Sathurnuru, R. “The Reaction of Acetic Acid 2-Selenoxo-2-pyridin-1-yl Esters with
Benzynes”, J. Heterocyclic Chem., (2004), 41, 13.
9. Sathunuru, R. and Biehl, E. R. “The Use CAN in the Regioselective Nitration of Phenols”,
ARKIVOC, (2003) (xv) 124-133.
10. Han, X. and Biehl, E. R. “Preparation of 1-Substituted and 1,4-Disubstituted Derivatives of
2,6-naphthyridine.” ARKIVOC, (2002), 40.
11. Lu, Y. Wu, C.-H. and Biehl, Ed. “The Reaction of 2-Chloro-1-methoxynaphthalene and 2Bromobiphenylene and 3-Cyanophthalides Under Aryne-forming Conditions: Convenient
Synthesis of Annular Polycyclic Aromatic Compounds. ARKIVOC (2002), 67-71.
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12. Rao, U. Narashima and Biehl, Edward R. “The Reaction of Acetic Acid 2-selenoxo-2Hpyridin-1-yl] Esters With Benzynes.”A convenient Route to Benzo[b]seleno[2,3-b]pyridines,
J. Heterocyclic Chem. (2004), 105.
13. Rao, U. Narasimha; Han, X. and Biehl, E. "Preparation of 3H-pyrrolo[2,3-c] isoquinolines
and 3H-pyrrolo[2,3-c][2,6]- and 3H-pyrrolo[2,3-c][1,7] naphthyridines. ARKIVOC, (2002),
981.
14. Han, X and Biehl, E. R. "Synthesis of 2,6-Naphthrydines", ARKIVOC (2002), 526.
15. Rao, U. Narashima and Biehl, Edward R. "Facile Preparation of Benzo[4,5thieno [2,3b]pyridines and Naptho[b-4,5]thieno[2,3-b] pyridines via the Reaction of Barton Esters and
Benzynes. J. Org. Chem, (2002, 67, 3409.
16. Wang, A., Wu, C-H. and Biehl, E. "Unambigious Synthesis and Spectral Characterization of
1,8-dihydroxy-4-methylanthraquinone". ARKIVOC 2002, 80.
17. Wang, A. and Biehl, E. "Reduction of Nitroarenes Using LDA". ARKIVOC 2002, 71.
18. Rao, U. Narasimha and Biehl, Edward R. "Convenient Synthesis of 3H-Pyrrolo-[2,3-c]
isoquinolines and 3H-Pyrrolo[2,3-c][1,7]-3,4-Benzo[c][1,7]-, and Dihydro pyrido[4,3c][1,8]-naphthyridines via Palladium-assisted Nucleophilic Amination Heterocycles,
Heterocycles, (2002) 56, 443-452.
19. Wang, A. and Biehl, E. "Facile Synthesis of 10-aryl derivatives of 9-aminoanthracenes and
9.10-dihydroanthracene-9-imines". ARKIVOC (2001) Vol. 2, 1004-1017.
20. A. K. Dast, J. J. Bellizzi, S. Tandel, E. Biehl, J. Clardy, and S. L. Hoffman. "Structural Basis
for the Insensitivity of a Serine Enzyme to Phenylmethylsulfonyl Flouride". J. Biol. Chem.
(2001) , 275, 23847.
21. Wang, A. and Biehl, E. "Lithium Diisopropylamide (LDA) Reduction of Nitroarenes.”
ARKIVOC, (2002) , 71.
22. Biehl, E. R. "The Use of Aryne Chemistry in the Synthesis of Nitrogen Containing
Heterocycles". Chapter in Recent Advances in Heterocyclic Chemistry, Vol. 4, edited by E.
Cotton, JAI Press, NY, (2000), pp. 251-293.
23. Wang, A. and Biehl, E. "Reaction of Chlorophenothiazine and Chloropromazine with
Nitriles in the Presence of LDA and LiTMP". Novel Preparation of 1-Amino Derivatives.
Heterocycles (2000), 53, 373.
24. Tandel, S.; Zhang, H.; Qadri, M.; Ford, G. P. and Biehl, E. R. "The Reaction of
Bromophenols with Arylacetonitriles in the Presence of LiTMP", J. Chem. Soc., Perkins
Trans I (2000), 587.
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25. Wang, A.; Zhang, H. and Biehl, E. "Preparation of N1-Alkyl-and N1, N1-Dialkylisoquinoline1,3,-diamines and 1-Alkyl- and 1-Phenylisoquinolin-3-amines From the Reaction of Dyaon-o-tolunitrile with Lithium Amides, Alkyllithiums, and Phenyllithium", Heterocycles
(2000), 53, 291.
26. Wang, A. and Biehl, E. "Facile Synthesis of 10-aryl derivatives of 9-aminoanthracenes and
9,10-dihydroanthracene-9-imines", ARIKOV (2001), Part 1, 156.
27. A. Wang, H. Zhang, E. R. Biehl. "The Preparation of Certain Nitrogen and Sulfur
Containing Polychclic Heterocycles by the Reaction of Arynes Possessing Charged Groups
with -lithio-e-thienylacetonitrile", Heterocycles (2000), 52, 1133.
28. Biehl, E. R.; Wendorf, F.; Landry, W,; Desta, A.; Watrous, L. "The Use of Gas
Chromatography and Mass Spectrometry in the Identification of Ancient Sorghum Seeds",
Chapter 7: The Exploitation of Plant Resources in Ancient Africa. Ed., M. v.d. Veen, Kluwer
Academic/Plenum Publishers, NWY, NY (1999), 47-53.
29. Tandel, S. and Biehl, E. R. "Reaction of 3-Chlorophyridinol and Arylacetronitriles".
Heterocycles (1999), 47, 453.
30. Biehl, E.; Wendorf, F.; Wasylikovowa, K.; Schild, R.; Dahlbert, J.; Miller, F.; Evans, J.;
Landry, W.; Han, W.; Watrous, L.; Desta, A.; Alibhai, I. "Use of GC-MS Analysis in the
Identification of 8000 Year ol Sorghum from the Egyptian Sahara". Proceedings of the
Afroarcheologicalbotany Symposium in Leichester, England, Plenum Press (1999). Spring
2000.
31. Wang, A.; Biehl, E. R. "A Novel 2+4 Cycloaddition of Benzyne-3-carboxylate". J. Chem.
Soc. Perkins Transation 1 (1998), 1461.
32. Tandel, S.; Wang, A.; Biehl, E. R. "The Reaction of 2-Chloro-4-nitrophenol and the
Isomeric Chloronitrobenzens with LDA Under Aryne-Forming Conditions". Tetrahedron
(1998), 15147.
33. Wang. A.; Zhang, H.; Biehl, E. R. "Preparation of 3-Benzyl-2-cyanobenzoic Acids from the
Reaction of Bromobenzoic Acids and Certain Arylacetonitriles with LDA in THF". J. Org.
Chem. (1998), 2415.
34. Wang, A.; Sagun, T.; Huang, Y.; Hodeman, T. C.; Biehl, E. R. "Preparation of 7Arylmethyl-1H-pyrrolo[3,4-c]pyridine-1,3-(2HO-diones and -Aryl-3-hydroxy-5-pyridylacetonitriles Using Arynic Methodology". Tetradedron (1998), 3391.
35. Wang, A.; Zhang, H.; Biehl, E. R. "Synthesis of Novel 3-Aminobenz[c,d]indo-2(1H)-ones
via Tandem Addition-Rearrangement Aryne Pathway". Heterocycles (1998), 46, 389.
36. Zhang, H.; Lu, Y.; Biehl, E. R. Acta Cryst. (1998), C54, 4512.
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37. Zhang, H.; Lu, Y.; Biehl, E. R. Acta Cryst. (1998), C54, 462.
38. Wang, A.; Biehl, E. R. "Investigation of the Reaction of 5-Bromonicotine Acid with Certain
Arylacetonitriles and LDA in THF". Heterocycles (1997), 45, 1929.
39. Zhang, H.-M.; Lu, Y.; Biehl, E. R. "Structure of 3-(2'-cyanobenzyl)-1-methoxy-2naphthonitrile", Acta Cryst. (1997), 2371.
40. Zhao, H.; Biehl, E. R. "Preparation of a Variety of naturally-Occuring Anthraquinones
Using an Aryne Reaction". J. Natural Products (1995), 58, 1970.
41. Refat, H. M.; Fadda. A. A.; Lu, Y.; Biehl, E. R. "Preparation of 8, 16-Imino-8-H, 16Hdinaphtho[2,1-b; 2,1-f][1-f][1,5]dioxocin". Heterocycles (1996), 42, 1280.
42. Tran, L.; Bhawal, B.; Biehl, E. R. "Synthesis of 4-arylated Tiglic Acid". Syn. Commun.
(1996), 26, 963.
43. Zhao, H. and Biehl, E. "Synthesis of -nitrilesulfones". Syn. Commun. (1995), 25, 4063.
44. Zhao, H. and Biehl, E. "Preparation of a Variety of Naturally-Occurring Anthraquinones
Using an Aryne Reaction". J. Nat. Prod., (1995), 58, 1970.
45. Refat, Hala Mohanned; Faddo, Ahmed A.; Biehl, Ed. "Reaction of
Bromopentafluorobenzene and Pentaflurophenyllithium with -Lithiated Arylacetonitriles".
J. of Fluorine Chem. (1996), 76, 99.
46. Han, Wei; Lu, Yingchun; Zhao, He; Dutt, Mahesh; Biehl, Edward R. "The Reaction of
Halogeno Substituted N, N-Dimethylanilines and Polycyclic Aromatic Hydrocarbons with
Certain Arylacetronitriles or Cyano-o-tolunitrile Under Aryne-forming Conditions".
Synthesis (1996), 59.
47. Fadda, A. A.; Berges, M. M.; Biehl, E. R.; Khalad, H. M. "Base Catalyzed Condensation
Reaction of Malonitrile, 2-Hydroxy-1-Naphthaldehyde with Different Ketones".
Heterocycles (1996), 0000.
48. Biehl, E. R.,; Refat, H.; Fadda, H. A. "Reaction of Pentafluoropyridine with _-Lithiated
Arylacetronitriles with _-Butyllithium in Ether". Heterocycles (1995), 41, 1431.
49. Biehl, E. R. and Ford, G. P. "Relative Stabilities of the ortho-Bisdehydro Polycyclic
Aromatice Hydrocarbons: Theoretical Calculations (AM1) and Simple Qualitative
Relationships." Tetrahedron Lett. (1995), 36, 3663.
50. Han, W.; Tran, J*.; Zhang, H.; Jeffrey, S*.: Swartling, D.; Ford, G. P.; Biehl, E. "4-Bromopyrenes with Arylacetonitriles Under Aryne-Forming Conditions". Synthesis (1995), 827.
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51. Rafat, H.; Waggenspack, J.; Dutt, M.; Zhang, H.; Faddo, A. A.; Biehl, E. R. "Reaction of
Hexachlorobenzene and Pentachlorophenyllithium with -Arylacetonitriles". J. Org. Chem
(1995), 60, 1985.
52. Biehl, E. R.; Rafat, H.; Faddo, A. A. "Reaction of Pentachloropyridine with _-Lithiated
Arylacetonitriles and Methyllithium in Diethylether". Heterocycles (1995), 41, 289.
53. Zhang, H. M.; Rafat, H. M.; Biehl, E. R. "Structure of _(3-Methoxyphenry)-2,3,5,6Tetrachlorophenylacetonitrile." Acta. Cryst. (1995), 3451.
54. Biehl, E. R.; Rafat, H.; Faddo, A. A. "Reaction of Pentachloropyridine 2,3,4,5-Tetrachloro4-Pyridyllithium with _-lithiated Arylacetonitriles and N-Butylithium". Heterocycles (1994),
38, 11, 2481.
55. Biehl, E. R. "Synthesis of Polycylics visaAryne-Arylation reaction". Chemia (1994), 48,
502.
56. Swartling, D. J.; Fry, M*.; Morgan, M*.; Biehl, E.; Balzarini, J.; DeClercq, E. "The
Synthesis and Antiviral Studies of 3'-Amino-2',3'-Dideoxythymidine/substituted 10-Cyano-9isothiocyano-anthracene Adducts." Nucleosides and Nucleotides (1994), 13, 2013.
57. Biehl, E. R.; Khanapure, J. P.; Hansen, M.*; Dutt, M.; Swartling, D. "Investigation of the
Reaction of 2-Bromo-1,4-Dimethoxynaphthalene and 9-Bromophenanthrene with Nitriles
Under Aryne-Forming Conditions". Synthesis (1994), 957.
58. Dutt, M.; Fravel, B.*; Ford, G. P.; Biehl, E. R. "Synthesis of Novel Anthrones Imines". J.
Org. Chem. (1994), 59, 497.
59. Dutt, M.; Zhang, H.; Biehl, E. R. "Preparation of 1-Aminoisoquinolines from the Reaction
of 2-Arylmethylbenzonitriles and Lithium Disopropyl Amide". Heterocycles Lett. (1994), 1,
9.
60. Khanapure, S. P.; Swartling, D.; Biehl, E. R. "Synthesis of Fluorine Substituted
Anthraquinones and Azaanthraquinones." J. of Flourine Chemistry (1994), 68, 131.
61. Swartling, D. J.; Fry, M. J.*; Morgan, M. B.*; Biehl, E. R. "The Synthesis of Subsituted 10Cynaoanthracene-9-Isothiocyanates for Use as Fluorescent Dye Labeling Reagents". J. of
Bioconjugate Chemistry (1994), 2357.
62. Biehl, E. R.; Deskmukh, A. R.; Dutt, M. "LDA-Mediated Reactions of 1-Naphthalynes with
Lithiated Acetonitriles and 1,4-Dipolar Nucleophilic Anions." Synthesis (1993), 885.
63. Biehl, E. R.; Fravel, B.*; Dutt, M. "Synthesis of 10-Imino Derivatives of Anthracenes." J.
Chem. Soc. Chem. Commun. (1992), 1520.
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64. Deshmukh, A. R.; Morgan, M. B.*; Tran, L.*; Biehl, E. R. "The Effect of Substituents on
the Computing TARA and Aryne-Arylation Reaction". Heterocycles (1992), 1239.
65. Deshmukh, A. R.; Tran, L.*; Morgan, M.*; Biehl, E. R. "Preparation of 9-Amino-10Anthracene-carbonitrites from the Reaction of Haloarenes and -Cyano-o-Tolunitrile".
Synthesis (1992), 765.
66. Deshmukh, A. R.; Zhang, H.; Tran, L.*; Biehl, E. R. "Tanden-addition Rearrangements in
the Reaction of 2-Butenoic Acid and n(-4-Methoxyphenyl)-2-Butenamide with Methyl
Substituted Benzynes". J. Org. Chem. (1992), 57, 667.
67. Deshmukh, A. R.; Biehl, E. R. "The Synthesis of 1-Amino-3,8-dipyridylmethyl-7-methylisoquinoline Involving a Tandem Addition-Rearrangement Pathway". Heterocycles (1992), 34,
99.
68. Deshmukh, A. R.; Tran, L.*; Biehl, E. R. "The Reaction of 2-Butenoic Acid Dianion and Its
N-(4-Methoxyphenyl) Amide With Methoxy-Substituted Arynes". J. Org. Chem. (1992), 57,
667.
69. Waggenspack, J. H.; Tran, L.*; Taylor, S. T.*: Yeung, L. K.*; Morgan, M. A.*; Deshmukh,
R.; Khanapure, S. P.; Biehl, E. R. "Synthesis of Polymethylphenylacetonitriles by the Arnye
Reaction". Synthesis (1992), 765.
70. Biehl, E. R., DePaul, S.*; Khanapure, S. P.; Self, J.*; Taylor, S.*; Tran, L. D.*: Tschantz,
M.*. Conference Proceedings, The Seventh International Conference on Phenothiazines and
Structurally Related Psychotropic Compounds, Krieger Publishers (1992), 41-48.
71. Biehl, E. R.; DePaul, S.*: Khanapure, S. P.; Tran, L.*: Taylor, S.*: Tschantz, M.*. "Crystal
Structure and Reactions of 7-Bromo-2-trifluoromethyl-10-methylphenothiazine".
Heterocycles (1991), 32, 0000.
72. Self, J.*; Khanapure, S. P.; Biehl, E. R. "Reaction of Chloro Derivatives of 10-Benzyl-and
10-(4'-Fluorobenzyl) phenothiazines with Nitriles and Amines Under Aryne-Forming
Conditions". Heterocycles (1991), 32, 311.
73. Self, Jennifer*; Khanapure, S. P.; Zang, H.; Biehl, E. R. "Structure of Cyano-Containing
Phenothiazine". Acta Cryst, C-47 (1991), 2465.
74. Khanapure, S. P.; Biehl, E. R. "A Novel Synthesis of Azaacridones Using 1,4-Dipolar Aryne
Cycloadditions". Heterocycles (1991), 32, 1773.
75. Bhawal, B. M.; Biehle, E. R. "Preparation of cis-Diphenyldibenzodicyclopentadiene". J.
Chem Soc. Chem. Comm. (1991), 743.
76. Self, J.*; Khanapure, S. P.; Zhang, H.; Biehl, E. R. "Reactions of Halo 10-Benzylphenothizines Under Aryne-Forming Conditions". Heterocycles (1991), 32, 343.
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77. Bhawal, B. M.; Khanapure, S. P.; Biehl, E. R. "Preparation of 10-Hydroxy-9-anthracenecarbonitriles and Corresponding Anthraquinones via Aryne Reaction". J. Org Chem. (1991),
56, 2846.
78. Bhawal, B. M.; Khanapure, S. P.; Biehl, E. R. "Methyl Ester of Phenylacetic Acids with
Lithium Alkoxides". Synthesis (1991), 112.
79. Khanapure, S. P.; Biehl, E. R. "The Use of 1,4-Dipolar Aryne Cycloaddition Strategy in
Anthracyclinone Synthesis: The Formal Synthesis of + 4-Demothoxydaunomycinone".
Synthesis (1991), 33.
80. Biehl, E. R., DePaul, S.*; Khanapure, S. P.; Self, J.*; Siriwardane, U.; Taylor, S.*; Tran, L.
S.*; Tschantz, M.*. "Synthesis and Reactions of 7-Bromo-2-trifluoromethyl-10methylpheno-thiazine Under Aryne-Forming Conditions. Heterocycles (1990), 31, 2209.
81. Bhawal, B. M.; Khanapure, S. P.; Biehl, E. R. "Rapid, Low-Temperature Amidation of Ethyl
Cyanoacetate with Lithium Amides Derived From Primary and Secondary Amines". Syn.
Commun. (1990), 20, 3235.
82. Khanapure, S. P.; Bhawal, B. M.; Biehl, E. R. "Use of N-Lithiated Ethyl Anthranilates as
1,4-Dipole Equivalents in 1,4-Dipole-Aryne Cycloaddition: A Novel Approach to the
Synthesis of Acridones". Tetrahedron Lett. (1990), 31, 2869.
83. Khanapure, S. P.; Biehl, E. R. "A Facile One-Step Synthesis of Novel Polysubstituted
Pyridines via Tandem-Addition Rearrangement-Aryne Reactions of 4-Bromo-2,6dimethoxy-3-(methoxymethyl)pyridine". Heterocycles (1990), 30, 505.
84. Siriwardane, U.; Khanapure, S. P.; Biehl, E. R. "9,11-Dihydro-1,6,11-trimethoxy-5,12naphthacenequinone". Acta. Cryst. (1990), C46, 924.
85. Khanapure, S. P.; Biehl, E. R. "Preparation of Novel 4-Substituted 6-Methoxy-6,7Dimethoxy-and 6,7-(Methylenedioxy)isochroman-3-ones. Part 2. J. Org. Chem. (1990), 54,
1471.
86. Siriwardane, L.; Crenshaw, L.; Khanapure, S. P.; Biehl, E. R. "Structure of anti-(2-cyano-3methoxy-6-methylphenyl)-1,2-diphenyl-1-ethanol". Acta Cryst. (1989), C45, 1463.
87. Khanapure, S. P.; Biehl, E. R. "Synthesis of morindapavin-A, An Anitumor Agent, and
Related Anthraquinones". J. Nat. Prod. (1989), 52, 1357.
88. Biehl, E. R. "Application of the Aryne Reaction in the Synthesis of Polycyclics". Accounts
of Chem. Research (1989), 22, 275.
89. Siriwardane, U.; Khanapure, S. P.; Biehl, E. R. "Structure of 8-Methoxy-5-methyl-3,4-cisdiphenylisochroman-1-one". Acta. Cryst. (1989), C45, 1239.
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90. Biehl, E. R.; Khanapure, S. P.; Siriwardane, U.; Tschantz, M.*. "The Reaction of 2-Chloro10-methylphenothiazine with Aromatic Nitriles and Lithium Dialkylamides in THF".
Heterocycles (1989), 29, 485.
91. Siriwardane, U.; Rawalpally, T. R.; Biehl, E. R. "Structure of N, N,-Diisopropyl -(2-methoxy-6-methyl)- -cyanoacetamide". Acta. Cryst. (1989), C45, 338.
92. Siriwardane, U.; Khanapure, S. P.; Chu, s. S.; Biehl, E. R. "6-(3-Methoxybenzyl)-5-methylo-anisonitrile". Acta Cryst. (1988), C44, 200.
93. Siriwardane, U.; Khanapure, S. P.; Chu, S. S.; Biehl, E. R. "2-(2,5-Dimethoxybenzl)-3,6dimethoxy-4-methlybenzonitrile". Acta. Cryst. (1988), C44, 374.
94. Khanapure, S. P.; Crenshaw, L. C.; Biehl, E. R. "Preparation of 2-Azaanthraquinones via
Aryne Reaction". Heterocycles (1988), 27, 2643.
95. Siriwardane, U.; Razzuk, A.; Biehl, E. R. "Crystal Structure of 10-(Phenyl)-5,10-Dihydro-NPhenylphenarsazine. J. Neterocyclic Chem. (1988), 25, 1555.
96. Crenshaw, L.; Khanapure, S. P.; Siriwardane, U.; Biehl, E. R. "A Stereocontrolled Synthesis
of cis-3,4-Diarylisochroman-1-one Through Diastereoselective Reaction of Benzaldehyde
and a-Lithio-2-cyanodiarylmethane Intermediate". Tetrahedron Lett. (1988), 29, 3777.
97. Siriwardane, Upali; Reddy, R. Thimma; Chu, S.S.C.; Biehl, Edward R. "1,2-Dihydro-5,6dimethoxybenzocyclobuten-1-(3',5'-dinitro)benzoate". Acta. Cryst. (1988), C44, 198.
98. Siriwardane, Upali; Khanapure, Subhash; Chu, S. C.; Biehl, Edward R. "Structure of (2Cyano-3-methoxy-6-methyl)-3-'methoxyphenylmethane". Acta Cryst. (1988), C44, 200.
99. Khanapure, Subhash P.; Crenshaw, Lori; Reddy, R. Thimma; and Biehl, Edward R.
"Synthesis of Polysubstituted Benzenes via the Tandem Addition-Rearrangement Aryne
Reaction of Substituted 2-Bromoanisoles and Lithioarenenitriles". J. Org. Chem. (1988),
53, 4915.
100. Khanapure, Subhash; Rawalpally, T. R.; Biehl, Edward R. "Preparation of
Anthraquinone via Aryne Reaction." J. Org. Chem. (1987), 52, 5685.
101. Siriwardane, Upali; Khanapure, Subhash; Biehl, Edward. "Structure of 2-(1,4Dimethoxy-2-naphthyl)-2-phenylacetronitrile 2,7-dimethoxynaphthylacetonitrile". Act.
Cryst. (1987), C43, 2246.
102. Razzuk, Aziz and Biehl, Edward R. "The Aryne Reaction of Polymethoxyhaloarenes
with Various Amines and Nitrile Anions". J. Org. Chem. (1987), 52, 3619.
Edward R. Biehl
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103. Khanapure, Subhash and Biehl, Edward F. "The Preparation of 4-Alkyl-and 4-Aryl
Derivatives of 6-Acetoxyisochroman-3-one". J. Org. Chem. (1987), 52, 1333.
104. de Meester, Patrice; Chu, Shirley S. C.; Khanapure, Subhash; and Biehl, Edward R. "a(2',5'-Dimethoxyphenyl)-3,4,5-trimethoxyphenylacetonitrile". Acta. Cryst. (1987), C43,
370.
105. Jovanovic, Misa V. and Biehl, Edward R. "Correlation of Bihedral Angles with 13C
Chemical Shifts of Quanternary Carbon Atoms of Some Phenothiazine and Pyrido[3,2b][1,4]benzothiazine Derivaties". J. Heterocyclic Chem. (1987), 24, 51.
106. Jovanovic, Misa V. and Biehl, Edward R. "Substituent and Solvents Effects on
Tautomeric Equilibrium of Barbituric Acid Derivatives and Isosterically Related
Compounds". J. Heterocyclic Chem. (1987), 24, 191.
107. deMeester, Patrice; Chu, Shirley S. C.; Jovanovic, Misa V.; and Biehl, Edward R.
"Structure of 3.7-Dibromo-10-ethylphenothiazine". Acta. Cryst. (1986), C42, 1794.
108. deMeester, Patrice; Chu, Shirley S. C.; and Biehl, Edward R. "Structure of 10-(4Nitrophenyl (pyrido[3,2ab][1,4]-benzothiazine". Acta. Cryst. (1986), C42, 877.
109. Xin, Han Yu; Khanapure, Subhas P.; Jovanovic, Misa V.; and Biehl, Edward R. "The
Reaction of 4-Bromo-1,2-dimethylbenzene with Various Nucleophiles via Aryne Reaction".
J. Org. Chem. (1986), 51, 5157.
110. Jovanovic, Misa V. and Biehl, Edward R. "Mechanism of the H/D/Exchange Mechanism
of Benzylbarbituric Acid Erivatives". Heterocycles (1986), 24, 3129.
111. Jovanovic, Misa V., Biehl, Edward R.; de Meester, Patrice; and Chu, Shirley S. C.
"Synthesis, 13C NMR Spectrum and Crystal Structure of 10-Phenyl-pyrido[3,2][1,4] benzothiazine 5-oxide. J. Heterocyclic Chem. (1986), 23, 797.
112. Jovanovic, Misa V., Biehl, Edward R.; de Meester, Patrice; and Chu, Shirley S. C.
"Determination of Structure and 13C Chemical Shift Assignments of the Nitration Products of
2-chloro-10-methylphenothiazine, X-ray Molecular Structure of 2-cholor-7-nitro-10methylphenothiazine-5-oxide". J. Heterocyclic Chem. (1986), 23, 801.
113. de Meester, Patrice; Chu, Shirley, S. C., Jovanovic, Misa V. and Biehl, Edward R.
"Crystal Structure of 2-Chloro-10-phenylphenothiazene". Acta. Cryst. (1986), C42, 750.
114. de Meester, Patrice; Jovanovic, Misa V.; Chu, Shirley S. C. and Biehl, Edward R.
"Investigation of the Structure and 13C NMR Spectrum of 5-Phenylbarbituric Acid". J.
Heterocycl. Chem. (1986), 23, 337.
115. Tate, John W. Tinnerman II*, William N.; Jurevics, Vita; Jeskey, Harold and Biehl,
Edward R. "Preparation of 5-substituted Barbituric Acids and Effect of the Benzyl and
Edward R. Biehl
10
substituted Benzyl Groups on the Acidity of Barbituric Acid". J. Heterocycl. Chem. (1986),
23, 9.
116. de Meester, Patrice; Chu, Shirley, S. C.; Jovanovic, Misa V. and Biehl, Edward R.
"Synthesis and Crystal Structure of 5-Methyl-5,10-dihydrophenarsazine". J. Heterocycl.
Chem. (1986), 23, 1131.
117. de Meester, Patrice; Chu, Shirley, S. C.; Jovanovic, Misa V. and Biehl, Edward R. "10(4' Methoxy)-pyrido [3,2-b][1,4]benzothiazine". Acta. Cryst. (1985), C41, 1246.
118. de Meester, Patrice; Chu, Shirley, S. C.; Jovanovic, Misa V. and Biehl, Edward R. "The
Crystal Structure of 3'-Methoxy-5-phenyl-5,10-dihydrophenarsazine". J. Heterocycl. Chem.
(1985), 22, 1237.
119. Chu, Shirley S. C.; de Meester, Patrice; Jovanovic, Misa V. and Biehl, Edward R. "The
Crystal Structure of 10-Methylphenothiazine 5-oxide". Acta. Cryst. (1985), C41, 1111.
120. Jovanovic, Misa V., Biehl, Edward R.; de Meester, Patrice; and Chu, Shirley S. C.
"Molecular Structure and 13C NMR Spectral Assignments of 1-(2'Pyrido)-pyrido[3,2-b][1,4]benzothiazine Using 10-Phenyl[3,2-b][1,4]benzothiazine as the Model Compound". J.
Heterocycl. Chem. (1985), 22, 777.
121. Han, Yu Xin; Jovanovic, Misa V and Biehl, Edward R. "The Reaction of 2-Bromo-1,4dimethoxybenzene with Various Nucleophiles via Aryne Reaction". J. Org. Chem. (1985),
50, 1334.
122. de Meester, Patrice; Chu, Shirley S. C.; Jovanovic, Misa V.; and Biehl, Edward R. "10(2-Methoxyphenyl)pyrido[3,2-b][1,4]benzothiazine, C18H14N2OS". Acta. Cryst. (1984), C40,
1753.
123. Jovanovic, Misa V. and E. R. Biehl. "13C Nmr Spectral Assignments of Chlorpromazine
and Its 5-Oxide. Literature Correction." J. Heterocycl. Chem. (1984), 21, 1589.
124. Jovanovic, Misa V., and E. R. Biehl, Patrice de Meester, and Shirley S. C. Chu. "Radical
Cation Formation and Crystal Structure Determination of 4'-Dimethylamino-10-phenylpyrido[3,2-b]benzothiazine". J. heterocyclic Chem. (1984), 21, 1425.
125. Jovanovic, Misa V. and Edward R. Biehl. "Crystal Structure Determination of 2-Nitro10-Phenyl-phenothiazine". J. Heterocyclic. Chem. (1984), 21, 885.
126. Jovanovic, Misa V. and Edward R. Biehl. "Crystal Structures of 10-(2'-Pyrazyl) Phenothiazine and Spectroscopic Identification of its radical-cation and dications". J. Heterocyclic
Chem. (1984), 21, 661.
127. Jovanovic, Misa V. and Edward R. Biehl. "Bromination of 10-Phenylphenothiazine and
10-Phenyl-phenoxazine". J. Heterocyclic Chem. (1984), 49, 1950.
Edward R. Biehl
11
128. Jovanovic, Misa V. and Edward R. Biehl. "13C Nuclear Magnetic Resonance and
Conformational Analysis of Some 10-Arylphenothiazines and 10-Arylpyridobenzothiazines".
Organic Magnetic Resonance (1984), 22, 491.
129. Xin, Han Yu and Edward R. Biehl. "Reaction of Various Nucleophiles with 2-Bromo-pxylene, 4-Bromo-veratrol and 4-Bromo-o-xylene via Aryne Reaction". J. Org. Chem.
(1983), 48, 4397.
130. Jovanovic, Misa V. and Edward R. Biehl. "One-Pot Synthesis and Structure of 10Hetero-arylphenothiazines". J. heterocyclic Chem. (1983), 20, 1677.
131. Uribe, Jose; Graham, Robert E. and Biehl, Edward R. "Determination of
Corticosteriods". J. Assoc. Off. Anal. Chem. (1983), 65, #3.
132. Sogandares-Bernal, F., M. V. Dennis, S. Graham*, E. Biehl, and M. Voge*. "Secretory
Excretory Antigens Produced by Tetrathyridia of Mesocestoides corti Defined by SDS-Page
and HLPC". Vet. Parasitology (1982), 10, 221.
133. Donato, Jr., H. and E. R. Biehl. "The Reaction of Nitro-Blue Tetrazolium with d, 1-LTetra-hydrofolate: The Effect of pH, Oxygen, Formaldehyde and Palladium (II)". ChemBiol. Inter, (1982), 39, 31.
134. Hansen, Lydell B.; Gabriel D. Castillo and Edward R. Biehl. "Gas ChromatographicMass Spectrometric Characterization of an Alteration Product of Malathion Detected in
Stored Rice". J. Assoc. Off. Anal. Chem. (1981), 64, #5, 1232.
135. Williams, Patricia and Edward R. Biehl. "High Pressure Liquid Chromatographic
Determination of Corticosteriods in Topical Pharamaceuticals". J. Pharm. Sci. (1981), 70,
530.
136. El-Sheikh, Mustafa I., Alan Marks, and Edward R. Biehl. "Investigation of the Synthesis
of Benzoxazoles via Aryne Reaction". J. Org. Chem. (1981), 46, 3256.
137. Sohal, Raj and Edward R. Biehl. "Effect of Age and Metabolic Rate on Lipid
Peroxidation in the Houseful". Musca domestica, Mechanics of Ageing and Development
(1981), 16, 159.
138. Graham, R. E., E. R. Biehl and C. T. Kenner. "Separation and Determination of
Testosterone and Testosterone Esters in Selected Pharmaceutical Formulations". J. Pharm.
Sci. (1979), 68, 871.
139. Shu, B., E. R. Biehl and P. C. Reeves. "General Synthetic Route to Monosubstituted
Cyclo-heptadienes from Organometallic Compounds". Synthesis (1978).
Edward R. Biehl
12
140. Bayoud, R., E. R. Biehl and P. C. Reeves. "Reaction of Unsymmetrically Subsituted
Pentadienyliron Tricarbonyl Cations in Water". J. Organometallic Chem. (1978), 150, 75.
141. Williams, Patricia and Edward R. Biehl. "Rapid Determination of Corticosteriods". J.
Pharm. Sci. (1978), 67, 792.
142. Biehl, E. R., W. Steward*, A. Marks*, and P. Reeves. "Influence of Cyano Group on
Orientation to Aryne". J. Org. Chem. (1979), 44, 3674.
143. Hanus, Jim, Humberto Guerrero and Edward R. Biehl. "Identification and Analysis of
Fraudulent Drugs". 1. Orotic adic LIB no. 2195, FSB/EDRO, Washington, DC.
144. Hanus, Jim, Huberto Guerrero and Edward R. Biehl. "Determination of Polynuclear
Aromatic Compounds in Shellfish". LIB no. 2119, FSB/EDRO, Washingon, DC.
145. Hanus, Jim, Humberto Guerrero, and Edward R. Biehl. "High Pressure Liquid Chromaographic Determination of Polynuclear Aromatic Hydrocarbons in Oysters". J. Assoc.
Official Anal. Chem. (1979), 62, 29.
146. Biehl, Edward R., Robert Wooten*, C. T. Kenner, and Robert E. Graham. "Kinetics and
Mechanistic Studies of the Blue Tetrazolium Reaction with Phenolhydrazines". J. Pharm.
Sci. (1978), 67, 927.
147. Graham, Robert E., Edward R. Biehl, and Charles T. Kenner. "Influence of Light on
Tetrazolium Reactions and Stability of Formazan in Various Solvents". J. Pharm. Sci.
(1977), 66, 965.
148. Graham, R. E., E. R. Biehl, and C. T. Kenner. "Analysis of Betamethasone and its
Organic Esters in Pharmaceutical Products". J. Pharm. Sci. (1978), 67, 360.
149. Pruitt, P., E. R. Biehl and P. C. Reeves. "Photochemical Reactions of 1,2Dimethylcyclobutadieneiron Tricarbonyl with Various Acetylenes". J. Org. Chem.
(1977),134.
150. Pruitt, P., E. R. Biehl and P. C. Reeves. "Substituent Effects in Cyclobutadieneiron
Tricarbonyl System". J. Chem. Soc. Perkin II (1977), 907.
151. Flynn, Bill and Edward R. Biehl. "Effects of Wne Conengers on Behavior in the Rat". J.
Studies on Alcohol (1977), 38, 25.
152. Graham, R. E., E. R. Biehl, C. T. Kenner, G. H. Luttrell, and D. L. Middleton.
"Mechanism of the Blue Tetrazolium Reaction". J. Pharm. Sci. (1977), 66.
153. Hanus, Jim, Huberto Guerrero, and Edward R. Biehl. "High Pressure Liquid
Chromatography of Benzo(a)phrene and Behzo(ghi)peryline in Oil-contaiminated Shellfish".
J. Assoc. Off. Anal. Chem. (1977), 59, 989.
Edward R. Biehl
13
154. Graham, Robert E., Edward R. Biehl, C. T. Kenner. "Effects of Solvent on Tetrazolium
Reaction". J. Pharm. Sci. (1976), 65, 1048.
155. Chiou, H. P. Reeves, and E. R. Biehl. "Mechanistic Aspects of the Bromintion of 10Substituted Phenothiazines". J. Hetero. Chem. (1976), 13, 77.
156. Biehl, Edward F., Levine, Robert. "Reaction of o-Chlorotoluene with alkali Amides.
Metal Effects in Benzyne Reaction". J. Org. Chem. (1975), 40, 2416.
157. Woods, T.*, T. Boyd*, E. Biehl, and P. Reeves. "Directed Effects in the Hydroboration
of Vinylferrocenes". J. Org. Chem. (1975), 40, 2416.
158. Biehl, E. R., H. Chiou, J. Keepers*, S. Kennard*, and Perry C. Reeves. "The Influence
of Substituents on Spectral Properties of Radical-Cations and Dications Derived from Certain
Phenothiazines". J. Hetero. Chem. (1975), 12, 397.
159. Graham, Robert E., Charles T. Kenner, and E. R. Biehl. "The Determination of
Iodochlor-hydroxyquin and Corticosteroids in Pharmaceutical Formulations". J. Pharm. Sci.
(1975), 64, 1013.
160. Graham, Robert E., C. T. Kenner, and Edward R. Biehl. "A Study of the Reduction of
Blue Tetrazolium by Corticosteriods". J. Pharm. Sci. (1975), 64, 226.
161. Biehl, Edward R., V. Patrizi*, S. Lapis*, and Perry C. Reeves. "Preparation of Certain 2N-Alkylamino-and2-N,N-Dialkylamino-10-methylphenothiazines via Phenothiazyne". (la),
J. Hetero. Chem. (1974), 11, 965.
162. Biehl, Edward R., and Perry C. Reeves. "Synthesis of Vinylcyclobutadieneiron
Tricarbonyl Complexes". Synthesis (1974), 883.
163. Stierle, D.*, Edward R. Biehl, and Perry C. Reeves. "Cyclobutadieneiron Tricarbonyl
Carboxylic Acids: Synthesis and Acidity". J. Org. Chem. (1974), 72, 221.
164. Biehl, E. R., S. Lapis*, and Perry C. Reeves. "Investigation of the Mechanism of
Reductive Dehalogenation of Haloanisoles Under Aryne-Forming Conditions". J. Org.
Chem. (1974), 39, 1900.
165. Biehl, Edward R., and Perry C. Reeves. "The Reaction of Vinylferrocenes with
Tetracyano-ethylene". J. Org. Chem. (1974), 39, 477.
166. Biehl, E. R., Tom Daniel*, P. C. Reeves, and Susan Lapis*. "Improved Synthesis of 3Bromo-10-Methyl-and 3-Bromo-10-Ethylphenothiazine". J. Hetero. Chem. (1974), 11, 247.
Edward R. Biehl
14
167. Biehl, Edward R., and Perry C. Reeves. "A Convenient, High-Yield Synthesis of the
Carboxylic Acid Derivative of Ferrocene and Cyclopentadienylmagnesium Tricarbonyl".
Synthesis (1974).
168. Biehl, Edward R., and Perry C. Reeves. "Hydroboration of Organometallic Compounds".
Tetrahydron Letters (1972), 2955.
169. Biehl, E. R., S. M. Smith*, S. Lapis*, and P. C. Reeves. "Elucidation of the Mechanism
of Reductive Dehalogenation of o-Haloanisoles under Aryne-forming conditions". J. Org.
Chem. (1972), 37.
170. Wu, A., E. R. Biehl, and P. C. Reeves. "Transmission of Substituent Effects in Phenoltricarbonylchromium Compounds". J. Chem. Soc. Perkin II (1972), 449.
171. Biehl, E. R., Susan M. Smith*, Robert Patrizi, and Perry C. Reeves. "Synthesis of N,NDialkylaromatic Amines via Benzyne Reaction". J. Org. Chem. (1972), 37, 137.
172. Biehl, E. R., Robert Patrizi, and P. C. Reeves. "Synthesis of Certain Meta Derivatives of
N-Alkylanilines via Aryne Reactions in Primary Aliphatic Amine Solvents". J. Org. Chem.
(1971), 36, 3252.
173. Wu, Angela*, E. R. Biehl, and P. C. Reeves. "Transmission of Substituent Effects in
Aniline-tricarbonylchromium Compounds". J. Org. Chem. (1971), 33, 53.
174. Biehl, Edward R., Susan M. Smith*, and Perry C. Reeves. "The Synthesis of NAlkylanilines via Aryne Reaction in Primary Armine Solvent". J. Org. Chem. (1971), 36,
1841.
175. Biehl, E. R., K. C. Hsu and Edward Nieh. "A Novel Catalytic Salt Effect in Base
Initiated Aryne Reactions and Dimethylamine Solvent". J. Org. Chem. (1970), 35, 2454.
176. Biehl, Edward R. and Edward Nieh. "Substituent Effects on the Reactivity of Arynes.
Product Distributions as Index of Relative Reactivities of Arynes in Methylamine and
Dimethylamine Solvents". J. Org. Chem. (1969), 34, 3595.
177. Biehl, Edward R., Edward Nieh, Hsueh-Ming li and Chun-I Hong. "The Orientation and
Reactivity in Nucleophilic Addition to Arynes Possessing Charged Substituents. 1.
Orientation and Reactivity in Nucleophilis Addition to Benzyne-3- and 4-Carboxylate". J.
Org. Chem. (1969), 34, 500.
178. Biehl, Edward R., and Hsueh-Ming Li. "The Quantitative Analysis of Mixtures of the
Isomeric Aminobenzoic Acids". Anal. Chem. (1966), 38, 1422.
179. Biehl, Edward R. "The Reaction of o-Chlorobenzoic Acid with Certain Active Hydrogen
Compounds and Sodamide in Liquid Ammonia". J. Org. Chem. (1966), 31, 602.
Edward R. Biehl
180.
15
Biehl, Edward F. "Semiconductors". Technical Report, USAG (1962).
181. Hollingsworth, D. W., Daryl McDaniel, Edward R. Biehl. "Lithium Aluminum Amides
as Catalysts for the Reaction of Lithium Aluminum Hydride with 1-Hexyne". J. Am. Chem.
Soc. (1960), 82, 3560.