Simulating Protein Synthesis: Creating a CHNOPS Creature
Procedure:
1. Determine the trait for Gene A. Code the DNA to mRNA and tRNA in table 1.
2. Next use the CODON and “Codon Table” to find each AMINO ACID.
3. Finally, find the trait that each amino acid sequence codes for in Table 2.
4. Repeat procedures 1-3 for Genes B-I
5. Make your own Gene J-L. Include the DNA, mRNA, tRNA, amino acid and trait it
would code.
6. Draw a picture of your CHNOPS Creature using the traits that you found.
TABLE 1: Genes on the CHNOPS Chromosomes
GENE A
DNA: ACC-GGT-TAT
mRNA:_____________________
GENE B
GENE C
DNA: ACG-CGA
DNA: TTT-AAC
mRNA:______________________ mRNA:______________________
tRNA:_____________________
tRNA:_____________________
tRNA:_____________________
aa Chain:____________________
aa Chain:____________________
aa Chain:____________________
TRAIT:_____________________
TRAIT:_____________________
TRAIT:_____________________
GENE D
GENE E
GENE F
DNA: GGA-CGC-CGA
DNA: GGG-AGG-AAA-CCC
DNA: CAA-CAA-CTA
mRNA:______________________ mRNA:______________________ mRNA:______________________
tRNA:_____________________
tRNA:_____________________
tRNA:_____________________
aa Chain:____________________
aa Chain:____________________
aa Chain:____________________
TRAIT:_____________________
TRAIT:_____________________
TRAIT:_____________________
GENE G
GENE H
GENE I
DNA: ACC-ATA-ATA
DNA: TAG-GGT-GCG
DNA: GTG-TTT
mRNA:______________________ mRNA:______________________ mRNA:______________________
tRNA:_____________________
tRNA:_____________________
tRNA:_____________________
aa Chain:____________________
aa Chain:____________________
aa Chain:____________________
TRAIT:_____________________
TRAIT:_____________________
TRAIT:_____________________
GENE J
GENE K
GENE L
DNA:
DNA:
DNA:
mRNA:______________________ mRNA:______________________ mRNA:______________________
tRNA:_____________________
tRNA:_____________________
tRNA:_____________________
aa Chain:____________________
aa Chain:____________________
aa Chain:____________________
TRAIT:_____________________
TRAIT:_____________________
TRAIT:_____________________
TABLE 2: Amino Acid Sequence and Traits
AMINO ACID SEQUENCE
Tryptophan-Glycine- Isoluecine
Tryptophan-Proline-Isoleucine
Tryptophan-Tyrosine-Tyrosine
Cysteine-Tyrosine-Tyrosine
Cysteine-Alanine
Cysteine-Proline
Arginine-Serine-Phenyalanine-Glycine
Proline-Serine-Phenyalanine-Glycine
Lysine-Luecine
Lysine-Phenyalanine
Proline-Alanine- Proline
Proline-Alanine-Alanine
Valine-Valine-Aspartic Acid
Valine-Valine- Glutamic Acid
Methionine-Glutamine-Arginine
Isoluecine-Proline-Arginine
Glutamine-Lysine
Histadine-Lysine
TRAIT
Hairless
Hairy
Plump
Skinny
Four-legged
Five-legged
Long Nose
Short Nose
Freckles
No freckles
Orange Skin
Blue Skin
Male
Female
Small Ears
Big Ears
One Eyed
Three Eyes
DON’T FORGET TO DRAW AND COLOR THE CHNOPS.
QUESTIONS:
1. What is translation?
2. What is transcription?
3. How are translation and transcription different?
4. Where is the specific site where transcription occurs?
5. What is the specific site that translation occurs?
6. How many tRNA nucleotide bases form the anticodon that attach to the mRNA codon?
7. How can one change in the DNA nucleotide base alter the formation of the amino acid sequence?