Curriculum Vitae
Name: Jiahao Sha
Academic qualifications: Ph.D
Previous academic positions held (with dates):
1981-1994
Assistant professor Nanjing Medical University
1994-1997
Associate professor Nanjing Medical University
1997-Now
Professor
Nanjing Medical University
Present academic position:
Professor and Supervisor of Ph.D and Head of Lab.
Previous relevant research work:
Jiahao Sha, Ph.D. (M), is a Professor and Director for the Laboratory of Reproductive Medicine, Nanjing
Medical University. Prof. Sha has 20 years expertise in the reproductive research. The relevant research work is
to clarify the mechanism underlying gametogenesis, including spermatogenesis, oogenesis and embryogenesis.
Previous funding records and experience in coordinating large-scale research projects:
2011-2016
Chinese National 973 Program (2011CB944300), chief scientist
The molecular mechanisms of stable transmission of genetic information in the sperm
2009-2011
Major research program of NSFC (90919014), project manager
Functions of Maternal proteins involved in modification of early embryogenesis
2006-2011
Chinese National 973 Program (2006CB504002), project manager
Sperm function related proteins and diseases
2006-2011
Chinese National 973 Program (2006CB944002), project manager
Sperm function related basic and clinical research
2007-2010
Major Program of National Natural Science Foundation of China (MNSFC, 30630030),
project manager
Expression and functional research of Human Testis Protein
2005-2008
National Science Foundation for Distinguished Young Scholars (30425006), project manager
Reproductive Physiology
2005-2006
Major State Basic Research Development Program of The Department of Science & Technology
China (2004CCA06800), project manager
Functional Research of NYD-SPn genes
2002-2004
National Natural Science Foundation of China (NSFC, 30170356), project manager
Construction Of Cloning And Expression Profile Of Human Ovary Developmental Genes
2000-2005
Chinese National 973 Program (G1999055901), project manager
Basic Research on Male Reproductive Health
Publication records:
Section A – Five most representative publications in recent five years
1.
Yu Y, Wu J, Fan Y, Lv Z, Guo X, Zhao C, Zhou R, Zhang Z, Wang F, Xiao M, Chen L, Zhu H, Chen W, Lin
M, Liu J, Zhou Z, Wang L, Huo R, Zhou Q, Sha J. Evaluation of blastomere biopsy using mouse model
indicates the potential high-risk of neurodegenerative disorders in the offspring. Mol Cell Proteomics.
2009;8:1490-1500.
2.
Yin L, Chung CM, Huo R, Liu H, Zhou C, Xu W, Zhu H, Zhang J, Shi Q, Wong HY, Chen J, Lu Y, Bi Y,
Zhao C, Du Y, Ma M, Cai Y, Chen WY, Fok KL, Tsang LL, Li K, Ni Y, Chung YW, Zhou Z, Sha J, Chan
HC. A sperm GPI-anchored protein elicits sperm-cumulus cross-talk leading to the acrosome reaction. Cell
Mol Life Sci. 2009; 66(5):900-8.
3.
Ma M, Guo X, Wang F, Zhao C, Liu Z, Shi Z, Wang Y, Zhang P, Zhang K, Wang N, Lin M, Zhou Z, Liu J,
Li Q, Wang L, Huo R, Sha J, Zhou Q. Protein expression profile of the mouse metaphase-II oocyte. J
Proteome Res. 2008;7(11):4821-30.
4.
Cui Y, Zhu H, Zhu Y, Guo X, Huo R, Wang X, Tong J, Qian L, Zhou Z, Jia Y, Lue YH, Hikim AS, Wang C,
Swerdloff RS, Sha J. Proteomic analysis of testis biopsies in men treated with injectable testosterone
undecanoate alone or in combination with oral levonorgestrel as potential male contraceptive. J Proteome
Res. 2008;7(9):3984-93.
5.
Huang XY, Guo XJ, Shen J, Wang YF, Chen L, Xie J, Wang NL, Wang FQ, Zhao C, Huo R, Lin M, Wang
X, Zhou ZM, Sha JH. Construction of a proteome profile and functional analysis of the proteins involved in
the initiation of mouse spermatogenesis. J Proteome Res. 2008;7(8):3435-46.
Section B – Five representative publications beyond the recent five-year period with the latest publication
entered first
1.
Zhu H, Zhu JX, Lo PS, Li J, Leung KM, Rowlands DK, Tsang LL, Yu MK, Jiang JL, Lam SY, Chung YW,
Zhou ZM, Sha JH, Chang Chan H. Rescue of defective pancreatic secretion in cystic-fibrosis cells by
suppression of a novel isoform of phospholipase C. Lancet
2.
2003;362:2059-2065.
Xu M, Xiao JH, Chen J, Li JM, Yin LL, Zhu H, Zhou ZM, Sha JH. Identification and characterization of a
novel human testis-specific Golgi protein, NYD-SP12. Molecular Human Reproduction 2003;9(1):9-17.
3.
Cheng LJ, Li JM, Chen J, Ge YH, Yu ZR, Han DS, Zhou ZM, Sha JH*. NYD-SP16, a novel gene
associated with spermatogenesis of human testis. Biology of Reproduction. 2003;68(1):190-198.
4.
Cheng LJ, Zhou ZM, Li JM, Zhu H, Zhu H, Zhou YD, Wang LR, Lin M, Sha JH. Expression of a novel
HsMCAK mRNA splice variant, tsMCAK gene in human testis. Life Science 2002;71(23):2741-2757.
5.
Zhou ZM, Sha JH, Li JM, Lin M, Zhu H, Zhou YD, Wang LR, Zhu H, Wang YQ, Zhou KY. Expression of
a novel reticulon-like gene in human testis. Reproduction 2002,123:227.