Curriculum Vitae PART I: General Information DATE PREPARED: August 10, 2001 Name: Wesley P. Fairfield, M.D. Office Address: Neuroendocrine Unit, BUL-457B Massachusetts General Hospital Boston, Massachusetts 02114-2696 E-mail: wfairfield@partners.org Fax: (617) 726-5072 Place of Birth: Biddeford, Maine Education: 1990 A.B. Bowdoin College Brunswick, Maine 1995 M.D. Harvard Medical School Boston, Massachusetts Postdoctoral Training: 1995-1996 Internship Internal Medicine Massachusetts General Hospital Boston, Massachusetts 1996-1998 Residency Internal Medicine Massachusetts General Hospital Boston, Massachusetts 1998-1999 Clinical Fellowship Endocrinology Massachusetts General Hospital Boston, Massachusetts 1999-2001 Research Fellowship Neuroendocrinology Massachusetts General Hospital Boston, Massachusetts Licensure and Certification: August 1997 Commonwealth of Massachusetts, Board of Registration in Medicine November 1998 ABIM Certification, Internal Medicine November 2000 ABIM Certification, Endocrinology & Metabolism Academic Appointments: 1995-1998 Clinical Fellow in Medicine Harvard Medical School Boston, Massachusetts 1998-2001 Research Fellow in Medicine Harvard Medical School Boston, Massachusetts 2001- Instructor in Medicine Harvard Medical School Boston, Massachusetts W. P. Fairfield Hospital Appointments: 1998-2000 Clinical and Research Fellow in Medicine Massachusetts General Hospital Boston, Massachusetts 1999- Consultant in Medicine, Associate Staff Massachusetts Eye & Ear Infirmary Boston, Massachusetts 2000- Assistant in Medicine Massachusetts General Hospital Boston, Massachusetts Major Administrative Responsibilities: 1999- Clinical Conference Coordinator Neuroendocrine Unit Massachusetts General Hospital Boston, Massachusetts 2000- Clinical Fellows Computer Orientation Neuroendocrine Unit Massachusetts General Hospital Boston, Massachusetts Professional Societies: 1998- The Endocrine Society Member 1991- Massachusetts Medical Society Member 1991- American Medical Association Member Awards and Honors: Bowdoin College 1990 Magna cum laude Graduate 1990 Summa cum laude, Biology Departmental Honors Massachusetts General Hospital 1999 The Endocrine Society Travel Grant Recipient Postgraduate Course on GH and Growth Factors - Metabolic Disorders Marstrand, Sweden 2000 Recipient, National Research Service Award, National Institutes of Health 2001 The Endocrine Society Travel Grant Award, Denver, Colorado PART II: Research, Teaching, and Clinical Contributions A. Narrative report of Research, Teaching, and Clinical Contributions My research focus stems from an interest in the neuroendocrine controls of body composition. I have trained as a research fellow under the tutelage of Dr. Anne Klibanski, Professor of Medicine at Harvard Medical School and Chief of the Neuroendocrine Unit. I have designed and implemented clinical trials investigating the physiology of glucocorticoid induced osteopenia and sarcopenia and the interactions with the growth hormone/IGF-I axis. As a staff physician in the Neuroendocrine Unit at Massachusetts General Hospital, I supervise and teach students, residents and clinical fellows. The Neuroendocrine Clinical Center attracts a variety of patients with pituitary diseases from all over the world. Teaching in the ambulatory setting is predominantly one-on-one and the experience is enriched by exposure to 2 W. P. Fairfield many different rare and fascinating disorders in the field of neuroendocrinology. In addition, neuroendocrine consultations for inpatients provides another venue in which I supervise and teach students, residents (medicine and surgery) and fellows about inpatient neuroendocrinology. B. Funding Information 1998-2000 NIH, Institutional NRSA PI: Joseph Avruch, M.D. 5 T32 DK07028-25 Training Program in Diabetes, Endocrinology and Metabolism 2000-2002 NIH, Individual NRSA PI: Wesley P. Fairfield, M.D. 1 F32 DK10122-01 IGF-I/BP-3 in glucocorticoid osteopenia and sarcopenia C. Report of Current Research Activities Mechanisms of glucocorticoid sarcopenia and osteopenia Investigator Interaction between glucocorticoids and GH/IGF-I axis Investigator Bone markers after GH receptor antagonist in acromegaly Investigator Cardiovascular risk in Crohn’s patients taking glucocorticoids Investigator D. Report of Teaching 1. Local contributions a. Harvard Medical School 1994-1995 Introduction to clinical medicine, Tutor 2 students, 4 hr/wk 12 months 1995 Introduction to clinical medicine, OSCE Evaluator 50 students, 6 hrs Two sessions 1998-1999 Patient Doctor I, Seminar on thyroid examination 50 students, 4 hrs Annual session 1999- Patient Doctor II, Clinical Preceptor 2 students, 4 hr/wk 2 months/yr e. Advisory and supervisory responsibilities in clinical or laboratory setting 2000 PASTEUR Clinical Research Program, Mentor Supervised 1 student working 40 hrs/wk 3 months/yr 2001 GCRC Summer Clinical Research Program, Mentor Supervised 1 student working 40 hrs/wk 3 months/yr 3 W. P. Fairfield 2000- Preceptor, Neuroendocrine Clinical Center Supervised fellows and residents 40 hrs/year PART III: Bibliography Original Articles Dickinson PS, Fairfield WP, Hetling JR, Hauptman J. Neurotransmitter interactions in the stomatogastric system of the spiny lobster: one peptide alters the response of a central pattern generator to a second peptide. J Neurophysiol 77 (2): 599-610, 1997. Fairfield WP, Finkelstein JS, Klibanski A, Grinspoon S. Osteopenia in eugonadal men with AIDS wasting syndrome. J Clin Endocrinol Metab 86(5): 2020-2026, 2001. Fairfield WP, Treat M, Rosenthal DI, Frontera W, Stanley T, Corcoran C, Costello M, Parlman K, Schoenfeld D, Klibanski A, Grinspoon S. Effects of testosterone and exercise upon regional body composition and muscle leanness in eugonadal men with AIDS wasting. J Applied Phys 90(6): 2166-2171, 2001. Reviews, Chapters, and Editorials Soyka LA, Fairfield WP, Klibanski A. Clinical review 117: Hormonal determinants and disorders of peak bone mass in children. J Clin Endocrinol Metab 85(11): 3951-63, 2000. Thesis Fairfield WP. Analysis of a contingent interaction between red pigment concentrating hormone and proctolin in the stomatogastric nervous system of the spiny lobster. Department of Biology, Bowdoin College, Brunswick, ME, 1990. Educational Material Fairfield WP. Neurocognitive dysfunction in patients with pituitary adenomas. MGH Neuroendocrine Clinical Center Bulletin 1999; 5(1): 4-7. Abstracts Cagliero E, Fairfield WP, Nathan DM. Quality of care provided to type 2 diabetic patients by endocrinologists and internists. American Diabetes Association Scientific Sessions, 1997. Fairfield WP, Berger LK, Klibanski A. Glucocorticoids decrease bone formation markers in healthy young women. The Endocrine Society 83rd Annual Meeting, Denver, CO, 2001. Fairfield WP, Sesmilo G, Katznelson L, Klibanski A. Effects of serum IGF-I normalization with a GH receptor antagonist on bone markers in acromegaly. The Endocrine Society 83rd Annual Meeting. Denver, CO, 2001. 4