Details of the programme, abstracts and curriculum vitae of the

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The Erasmus Mundus Lecture Series on

Nanotechnology in Modern Society

Herman E. Maes, IMEC, Leuven, Belgium

10 October 2007

12 February – 20 May 2008

The Erasmus Mundus Lecture Series Erasmus Mundus Master of

Nanoscience and Nanotechnology

Nanotechnology in Modern Society

Nanoscience and nanotechnology are relatively new subjects and as such they are accompanied by many uncertainties as to their impact on modern society. Nanotechnology does not only refer to techniques that are used to study the world at nanometer scale (the scale of a few atoms) but also to the technology used to design and fabricate the building blocks with nano-scale precision. These building blocks will allow the development of revolutionary new materials, consumer articles and appliances, a promise already made for years now by nano-scientists. But when can we really expect these new applications? And how can one deal with these technologies in a responsible way?

These are the type of questions that will be treated in this new Series of

Lectures. In the academic year 2007-2008, 8 lectures will be given by international experts on various topics such as new important developments in nanotechnology, the opportunities for nanotechnology applications, the ethics and risks of nanotechnology developments. These

Lectures are organized during the second semester of the Academic Year.

This year however one seminar was already organized in the first semester, on 10 October 2007.

These Lectures are an integral part of the Erasmus Mundus Master program but are also open to others interested in these important and fundamental and societal aspects. The lectures are organized using a

Virtual Classroom concept in which all participating universities will be linked. Each lecture will be followed by a discussion session involving the lecturers, the students and nanotech professionals

Where?

The Virtual Classroom Lectures for Leuven, Belgium take place at the

Audio-Visual Department of the Katholieke Universiteit Leuven

AVNet

Kapeldreef 62

3001 Heverlee

België

Route met de wagen

Via E40 Brussel-Luik en E314 Lummen-Leuven: u verlaat de autosnelweg via uitrit 15 (Leuven). De expresweg die u nu volgt, is de Koning

Boudewijnlaan. Op het tweede kruispunt met verkeerslichten slaat u rechtsaf

(Celestijnenlaan).

Vanaf de Celestijnenlaan slaat u de tweede straat rechts in (Kapeldreef).

AVNet bevindt zich in het laatste gebouw, vlak naast het Innovatie- en Incubatiecentrum

K.U.Leuven.

Lecture Series Erasmus Mundus Master of

Nanoscience and Nanotechnology

Nanotechnology in Modern Society

Speakers and Topics

Wednesday, 10 October 2007, 5-7pm

Prof. Yoshishige Suzuki, Osaka University, Japan

Spin-injection, Spin-Torque Diode Effects and future

Tuesday, 12 February 2008, 5-7pm

Prof. Victor Moshchalkov, K.U.Leuven, Belgium

Enhancing Superconducting Critical Parameters through Nanostructuring: Dream or Reality?

Tuesday, 19 February 2008, 5-7pm

Prof. Gianaurelio Cuniberti, Institute of Materials Science, TU Dresden, Germany

Tuning the conductance of a molecular switch

Tuesday, 11 March 2008, 5-7pm

Dr. Zoran Konkoli, Chalmers University of Technology, Göteborg, Sweden

Diffusion controlled reactions in small and structured spaces as a tool for describing living cell biochemistry

Tuesday, 18 March 2008, 5-7pm

Dr. Stephan Grill, Max Planck Institute of Molecular Cell Biology and Genetics and

Max Planck Institute of Physics of complex Systems, Germany

Transcription by RNA Polymerase II

Tuesday, 8 April 2008, 5-7pm

Dr. Sven Rogge, TUDelft, The Netherlands

The Transistor: from Shockley, Bardeen, and Brattain to single molecules and atoms

Tuesday, 6 May 2008, 5-7pm

Prof. Fredrik Höök, Chalmers University of Technology and Lund University,

Sweden

Miniaturized Bioanalytical Sensors : Challenges and Opportunities

Tuesday, 13 May 2008, 5-7pm

Dr. Hans-Georg Braun, Max Bermann Center, IPF, Germany

The impact of military research on nanotechnology

Wednesday, 10 October 2007, 5-7pm

Prof. Yoshishige Suzuki, Osaka University, Japan

Spin-injection, Spin-Torque Diode Effects and future

Spin-injection magnetization switching technique [1] made it possible to control magnetization by a direct current. A discovery of spontaneous rf oscillation from

CPP-GMR nano-pillars and a real time observation of the switching process have revealed essential amplification function of a precession in the magnetic nano-pillars under a direct current [2]. Beside of those progresses, developments of giant tunneling magneto-resistive (GTMR) effect using an MgO barrier [3] made it possible to utilize a very large resistance change according to the magnetization switching.

In this talk, several attempts to utilize interplay between spin-torque and giant-TMR effect will be presented referring to a “spin-torque diode effect”[4] and other properties such like rf noise control and possible signal amplification using magnetic tunnel junctions (MTJs).

If time allows, new results on the spin-injection into the C60[5], Rubrene, Alq3 and graphine[6] will be introduced.

References:

[1] J. C. Slonczewski, J. Magn. Magn. Mater. 159, L1 (1996) , L.

Berger, Phys. Rev. B 54, 9353 (1996), and E. B. Myers, et al., Science 285, 867

(1999).

[2] S. I. Kiselev et al., Nature 425, 380 (2003), I. N. Krivorotov et al., Science, 307,

228 (2005).

[3] W. Wulfhekel, et al. Appl. Phys. Lett. 78, 509--511 (2001), M.

Bowen, et al. Appl. Phys. Lett. 79, 1655--1657 (2001), J.

Faure-Vincent, et al. Appl. Phys. Lett. 82, 4507--4509 (2003), S.

Yuasa, et al., Jpn. J. Appl. Phys. Part 2, 43, L588 (2004), S. Yuasa, et al., Nature Mat.

3, 868 (2004), S. S. P. Parkin et al., Nature Mat.

3, 862 (2004), and D. D. Djayaprawira et al., Appl. Phys. Lett. 86,

092502 (2005).

[4] A. A. Tulapurkar, et al., Nature, 438, 339 (2005).

[5] S. Miwa, et al., “Spin-Dependent Transport in C60-Co Nano-Composites”,

Japanese Journal of Applied Physics, Vol. 45, No.

28, 2006, pp. L717-L719.

[6] M. Oishi, et al., “Spin injection into a Graphene thin film at room temperature”,

Japn. J. Appl. Phys., 46, No. 25 (2007) L605-L607.

Prof. Dr. Yoshishige SUZUKI

Affiliation:

Full professor at Osaka University, Graduate School of Engineering Science,

Department of Materials Engineering Science,

Career:

March 1984 Master degree, Tsukuba University

"Current controlled LPE growth of GaAs"

Apr. 1984 Electrotechnical Laboratory, AIST, MITI, Japan (Researcher)

"Research on magnetic artificial superlattices".

July, 1990 Doctor of Engineering Science, Tsukuba University

(by paper application.)

Aug. 1993-Sep. 1994 Visiting scientist at Universite Paris-Sud,

Institute d'electronique fondamentales Apr. 1998- Electrotechnical Laboratory,

AIST, MITI, Japan (Labo. Leader)

"Nanostructured spin-electronics materials"

Apr. 2001- Institute of Advanced Industrial Science and Technology(AIST)

(Senior Researcher / Group Leader)

“Researches on spintronics-devices and materials”

Mar. 2003- Osaka University, Graduate School of Engineering Science, (Professor)

“Researches on spintronics-devices and materials”

Apr. 2003- Guest researcher at AIST, Tsukuba

Aug. 2007- Visiting fellow at IMEC

Tuesday, 12 February 2008, 5-7pm

Prof. Victor Moshchalkov, K.U.Leuven, Belgium

Enhancing Superconducting Critical Parameters through Nanostructuring:

Dream or Reality?

Superconductivity is a remarkable example of macroscopic quantum phenomena. It exists only below the critical surface in the space of the three variables: temperature – magnetic field – current. Superconducting condensate is confined by the sample boundaries, very much like the wave function being confined by a quantum box.

Through the optimisation of the confinement, the superconducting critical parameters can be substantially improved. This concept of nanostructuring is applied systematically to different nanostructured superconductors by moving from individual nanoplaquettes via their clusters to their huge arrays.

If boundaries of nanostructures themselves define a potential well confining the quantum condensate of Cooper pairs, then why not to use it to tune superconducting critical parameters by changing only the topology of the samples taking the same superconducting material to make these samples? This was checked in experiments on the samples of different topology: the critical field separating the normal from the superconducting state indeed has turned out to be strongly topology dependent! It means that the statement “critical fields of a superconductor are determined by the material”, mentioned in textbooks on superconductivity, is not correct for nanostructured materials for which the superconducting critical field is dependent not only on material but also on the topology and the length scale used for the nanostructuring of that material. Lateral nanostructuring can in fact create such conditions for the flux line pinning by huge arrays of nanofabricated antidots or magnetic dots which maximize also the second important superconducting critical parameter - critical current- up to its theoretical limit - depairing current. It implies that “quantum design” of the two important superconducting critical parameters - critical current and critical field – is a reality.

This work was supported by the Belgian IAP, the Flemish GOA and FWO

Programmes and the ESF “NES” Programme.

Professor Victor V. Moshchalkov

M.Sc. in Physics, 1975, cum laude, ranking the first among 450 M.Sc graduates in Physics;

Ph.D in Physics, 1978; “Habilitation”, 1985; Head of the Laboratory of High Temperature

Superconductivity, 1988-1991; - all at Lomonosov Moscow State University; Professor of

Physics at the K.U.Leuven, 1991- up to now, since 2005 – Director of INPAC-Institute for

Nanoscale Physics and Chemistry. Over 640 publications in international journals - more than

6800 SCI-citations. Promoter of 37 Ph.D theses. Chairman of the ESF Pogrammes VORTEX,

1999-2004; NES, 2007-… Co-Editor “Superconductor Science and Technology” 2007-…,

“Physica C” 2007-….

Laureate of the USSR State Prize for Young Researchers, 1986; Laureate of the USSR Ministry of High Education Scientific Prize, 1988; ISI Thomson Scientific Award

“Top Cited Paper in Flanders”, 2000; Laureate of the Belgian FWO Dr. A. De Leeuw -Damry-

Bourlart Prize for Exact Sciences, 2005.

Tuesday, 19 February 2008, 5-7pm

Prof. Gianaurelio Cuniberti, Institute of Materials Science,

TU Dresden, Germany http://nano.tu-dresden.de/new/

Tuning the conductance of a molecular switch

One key element to realize nanoscale electronics is the ability to manipulate in a controlled way the conductance of single molecules. Azobenzene, which undergoes a trans-cis isomerization transition upon irradiation, offers the possibility to realize a conformational, light-driven molecular switch. It is thus crucial to clarify the electrical transport characteristics of this molecule. Here, we investigate theoretically charge transport in a system consisting of carbon nanotubes (CNTs) acting as electrodes which are bridged by cis/trans azobenzene. In clear contrast to Au-electrodes, CNTs can act as true nanoscale electrodes, inducing a strong chirality-dependent renormalization of electronic states near the Fermi level. The low energy conduction properties may thus be dramatically modified by changing the molecule-CNT contact topology and/or the tubes chirality. We propose some possible experimental ways to realize a controlled electrical switching with CNT electrodes.

[1] M. del Valle, R. Gutiérrez-Laliga, C. Tejedor, and G. Cuniberti, Nature

Nanotechnology 2 , 176 (2007); arXiv:0705.0527v1

Figure caption: Schematic view of the unimolecular switching device.

Prof. Dr. Gianaurelio Cuniberti

Affiliation

Institute for Materials Science, Dresden University of Technology

Career

1970

1981

1997

1998

Born, April 28, Genoa, Italy

Laurea (M.S.) in Physics University of Genoa, Italy

Ph.D. in Theoretical Physics University of Genoa, Italy

Post Doc University of Hamburg, Germany

1999-2002 Guest scientist Max Planck Institute for the Physics of

Complex Systems, Dresden, Germany

2003 -2008 Group Leader

2007

University of Regensburg, Germany

Chair Professor (W3, Ordinarius), Dresden University of Technology,

Germany

Tuesday 11 March 2008, 5-7pm

Dr. Zoran Konkoli, Chalmers University of Technology, Sweden

Diffusion controlled reactions in small and structured spaces as a tool for describing living cell biochemistry

Chemical reaction kinetics in vivo differs significantly from the one in pipette and care has to be taken when devising computational frameworks or experimental setup to deal with such environment. For example, geometry can be quite complicated and there is an experimental evidence that cell is structured in many ways, already starting that the cytoplasm level. Cytoplasm is not smooth and homogeneous; for a single cell total amount of protein content can be as high as 17-30% by weight which results in extremely structured and crowded space. In addition, cell interior (roughly 10 in diameter) is further partitioned in smaller spaces such as organelles (e.g. mitochondria with 50 nm in diameter), and roughly 50% of cell volume is filled by organelles. Also, for typical physiological concentrations one has ca 1000 copies of individual protein molecules which results in large spatial fluctuations of protein number across the cell interior and delivery of proteins can become an issue.

Which theory should one use to describe such environment? The lecture will provide some of the answers to this question.

Prof. Zoran Konkoli

Associate Professor in the field of Theoretical and Applied Biology since 2007.

Zoran received his PhD in 1996 in the field of Theoretical Chemistry and since then worked on number of problems on border between Physics, Chemistry, and Biology.

Zoran actively contributed in developing methods for theoretical analysis of wide range of problems: diffusion controlled reactions (many-particle density function formalism, field theory, stochastic simulation, and number of other methods); macromolecular dynamics (protein folding, polymer translocation); Quantum

Chemistry first principle calculations (multi-configuration perturbation theory, vibrational spectroscopy). His current research interests focus on understanding workings of diffusion controlled reactions in environments reminiscent of the living cell (structured spaces with large, medium, and small volumes) and development of appropriate calculation methods. His research interests are clustered around understanding various topics related to metabolic control, signalling, chemotaxis, and biocomputing.

Tuesday, 18 March 2008, 5-7pm

Dr. Stephan Grill, Max Planck Institute of Molecular Cell Biology and Genetics and

Max Planck Institute of Physics of complex Systems, Germany

Transcription by RNA Polymerase II

RNA polymerase II (RNAP II) is responsible for transcribing all mRNAs in eukaryotic cells in a highly regulated process that serves as a central control point for cellular function. We have investigated the transcription dynamics of single RNAP II molecules against force in the presence and absence of TFIIS, a transcription elongation factor that enables the enzyme to remove copy errors. Using a single- molecule dual-trap optical-tweezers assay, we found that the response of RNAP II to force is entirely determined by enzyme backtracking. We show that backtrack pause durations follow a t^−3/2 power law, implying that during backtracking RNAP II performs a random walk in discrete base-pair steps and suggesting that backtracks may account for most of RNAP II pauses. Unexpectedly, we find the polymerase to be naturally biased in the downstream direction while backtracked, possibly due to transient secondary structures that form behind the polymerase within the RNA transcript. Finally, we propose that this intrinsic force bias is a novel mechanism that is central to transcription and that acts to prevent the occurrence of fatally long pauses.

Dr. Stephan Grill

From 2006

Group-Leader, jointly at the Max-Planck-Institute of Molecular Cell Biology and

Genetics, Dresden, and the Max-Planck-Institute for the Physics of Complex Systems,

Dresden

2004-2005

Postdoctoral work at the Department of Physics, University of California in Berkeley

2003

Postdoctoral work at MPI-CBG Dresden

1998-2002

PhD work at EMBL Heidelberg; PhD in Physics from the Technical University

München

Tuesday, 8 April 2008, 5-7pm

Dr. Sven Rogge, TUDelft, The Netherlands

The Transistor: from Shockley, Bardeen, and Brattain to single molecules and atoms

In this lecture we will review the working principles of transistors and their evolution from the first bipolar device in 1947 to state-of-the-art field-effect nanodevices that will power future computers. This evolution was not only based on the invention of the transistor concept. The key development was actually material control--

Germanium in the beginning, then Silicon, now compound semiconductors--which remains a core issue for today’s nanodevices. We will focus both on the quest for smaller, faster and more energy efficient industrial devices as on the ultimate limit of transistors where a single molecule or atom determines the current flow in the device.

The functionality of the latter is not based on the evolutionary scaling of the original transistor concept, but rather on the quantum nature of the device. Besides the bulk physics of the bipolar and field-effect transistor, the atomistic approach needed to understand the ultimate limit of transistors such as resonant tunneling, charging and orbital effects will be discussed. Finally, a brief outlook will be given on the combination of electronics and photonics which is a current trend to solve communication problems on ultrafast chips and enhance their functionality.

Dr. Sven Rogge

Sven Rogge, age 37, obtained his Ph.D. from Stanford University in 1997 (Stanford,

USA). In 2003 he was appointed as faculty member at the Kavli Institute of Nano-

Science (Delft, The Netherlands) where he is the group leader for atomic-scale electronics.

Tuesday, 6 May 2008, 5-7pm

Prof. Fredrik Höök, Chalmers University of Technology and Lund University,

Sweden

Miniaturized Bioanalytical Sensors : Challenges and Opportunities

Within diagnostics and drug discovery there is currently an eager search for new technical solutions that provide high-through-put analysis of pathogenic markers and drug candidates. The intensive research devoted to this area has provided numerous new bioanalytical concepts capable of detecting biorecognition reactions related to many disease states. However, despite promising, very few of these techniques have yet reached the clinics or the pharmaceutical industry. The reasons for this are many fold, but there is no doubt that one critical component is the need for more efficient interdisciplinary research efforts. In parallel with the progress made by electrical, physical and chemical engineers, who currently make significant progress with respect to highly sensitive transducer principles, biochemists, biophysicists and biologists gain deeper and deeper insights about the chemical pathways that orchestrate living organisms. With particular emphasis on means to probe cellmembrane mediated biorecognition reactions, the importance of interdisciplinary efforts will be exemplified by presenting our work devoted on miniaturized bioanalytical sensors.

Besides the challenges that must be overcome in order to eventually reach practical applications, I will discuss in some detail our current efforts aimed to extend already well-established macroscopic sensors to highly miniaturized formats, exemplified with label-free single-molecule studies and localized-surface plasmon resonance concepts made compatible with studies of cell-membrane mimics.

Prof. Dr. Fredrik Höök

FREDRIK HÖÖK

is a Professor of Biological Physics at Chalmers University of Technology, Göteborg,

Sweden. In 1992, he earned a master degree in physics from Chalmers University of Technology, Sweden. In

1997, he completed Ph.D. studies in physics at Chalmers, where he worked under the supervision of Prof. Bengt

Kasemo (Dept of Applied Physics) and Prof. Peter

Brzezinski (Dept of Biochemistry and Biophysics). From

1998-2000, he was Postdoctoral Fellow under the direction of Prof. Hans Elwing at the Dept of Cell and

Molecular Biology, Göteborg University. He was appointed Assistant Professor of biological physics at

Chalmers in 2000. In 2004 he was appointed professor in nanoscience for biophysics at the Dept of Physics at Lund

University, Sweden, and moved in 2007 to his current position at Chalmers. He has been granted several awards and honors for his research, including AkzoNobels Nordic research award in 2002 and the prestigious Individual Grant for the Advancement Research Leaders in 2005. He has authored more than 50 research publications, including PNAS, JACS and Nano

Letters, and has many patents and patents pending. He is co-founder of Q-Sense AB,

Sweden, who manufactures the internationally recognized quartz crystal microbalance with dissipation (QCM-D) monitoring technique and LayerLab AB, who develops smart lipid-based surface modifications. Professional activities include participation in numerous scientific societies and consultation on research directions for Swedish and

European funding agencies. His research is currently funded by several federal

(including European) and industrial sources. His current research interests include miniaturized bioanalytical sensors, supported cell-membrane mimics, antibody arrays and micro-/nanofluidics.

Tuesday, 13 May 2008, 5-7pm

Dr. Hans-Georg Braun, Max Bermann Center, IPF, Germany

The impact of military research on nanotechnology

The success of military actions either offensive or defense measures has often been related to the progress in military based research. During history several people of high reputation in art, science and engineering such as Archimedes or Leonardo da

Vinci were engaged in the development of “military machinery”.

From the beginning of the still increasing interest in nanotechnology (around 1990) some enthusiastic interest from military people for this area of science could be recognized. It even increased after September 11 due to new technological demands related to the “US war against terrorism”. With respect to these developments a number of questions arises as for example:

1) What are the main areas of interest in nanotechnology (from the viewpoint of military people)?

2) How much do especially the US support military oriented research at universities and public research institutions ?

3) Can we already recognize areas of research that are still highly speculative but that could have a strong impact on the civil society both negative and positive?

4) Has a new race in the nanotechnology armament already started or is it about to start?

The lecture should address some areas of interest which are still at the fundamental research level and which could branch both into a useful or dangerous direction for the future social existence.

Dr. Hans-Georg BRAUN

Affiliation:

Group leader at the Leibniz Institute of Polymer Research Dresden , Max Bergmann

Center of Biomaterials

Career:

1980

1980-1984

1984-1985

Diploma in chemistry at the University of Freiburg i. Br.

(Thesis on “

Electron microscopic investigations on the the oligomerisation and polymerization of Distyrlpyrazine”

PhD Thesis at the Institute of Macromolecular Chemistry of Freiburg with

Prof. G. Wegner on the topic: The oligomerisation of Distyrylpyrazine in the solid state – A topochemical single crystal to single crystal reaction (1980/81)

Guest visitor at the Institut of Materials Science University of Saarbrücken at

Prof. Gleiter / Prof. Petermann)

Post-doc at the Dept. of Chemical Eng. University of Kyoto (Japan) with

Prof. T. Hashimoto

1985-1994 Head of the Electron Microscopy Laboratory at the Polymer Physics departement of BASF Central Research Laboratory in Ludwigshafen

1994-today Head of the Polymer Micro- and Nanostructure Group at the IPF (Max

Bergmann Center of Biomaterials)

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