ANTECH DIAGNOSTICS 17672-A Cowan Avenue Irvine CA 92614 Phone: 800-745-4725 Hemopet/Hemolife 11330 Markon Dr Garden Grove, CA 92841 Accession No. Doctor HPBC00183706 FINK Species Canine Client # 20073 Chart # N Owner WAITZ Krista Sex Male Breed Labradoodle Pet Name TP CASPER Received 12/05/2006 Pet Age 3Yrs Reported 12/11/2006 12:02 PM 28.4 lbs Test Requested T3 (RIA) T3 (RIA) T4 T4 FREE T3 Free T3 FREE T4 (RIA) Free T4 (RIA) T3 AUTOANTIBODIES T3 Autoantibodies T4 AUTOANTIBODIES T4 Autoantibodies THYROGLOBULIN AUTOANTIBODIES Thyroglobulin Autoantibody Results Reference Range Units 95 45-150 ng/dL 1.58 1.0-4.0 g/dL 4.5 1.7-5.3 pg/mL 0.69 0.45-2.06 ng/dL 0.7 Less Than 2.0 0.9 Less Than 2.0 6 NEGATIVE -------------- TGAA SCREENING TEST INTERPRETATION -----------------< 20% = Negative; 20%-35% = Equivocal; > 35% = Positive ... Elevated TGAA levels confirm autoimmune thyroiditis. False positive results can occur if the dog has been vaccinated within 30 to 40 days. Thyroid hormone supplementation can decrease TGAA levels. ... All equivocal and positive TGAA screening test results are verified by the confirmatory NSB (non-specific binding) test. -------------------------------------------------------------------TEST PERFORMED AT ANTECH'S NEW YORK LABORATORY % 12/11/2006 Dear Colleague: The TgAA is negative, so his sluggish basal thyroid levels are not due to autoimmune thyroiditis at this time. Please refer to earlier report for treatment suggestions. Jean cc: By e-mail to client at kristaw@cfl.rr.com Page 1 FINAL 12/11/2006 12:02 PM ANTECH DIAGNOSTICS 17672-A Cowan Avenue Irvine CA 92614 Phone: 800-745-4725 Hemopet/Hemolife 11330 Markon Dr Garden Grove, CA 92841 Tel: 714-891-2022 Fax: 714-891-2123 Client # 20073 Chart # N Accession No. HPBC00183706 Doctor FINK Species Canine Breed Labradoodle Owner WAITZ Krista Sex Male Pet Name TP CASPER Received 12/05/2006 Pet Age 3Yrs Reported 12/06/2006 10:11 AM 28.4 lbs Test Requested Results T3 (RIA) T3 (RIA) 95 T4 T4 1.58 FREE T3 Free T3 4.5 FREE T4 (RIA) Free T4 (RIA) 0.69 T3 AUTOANTIBODIES T3 Autoantibodies 0.7 T4 AUTOANTIBODIES T4 Autoantibodies 0.9 THYROGLOBULIN AUTOANTIBODIES (Pending) Reference Range Units 45-150 ng/dL 1.0-4.0 g/dL 1.7-5.3 pg/mL 0.45-2.06 ng/dL Less Than 2.0 Less Than 2.0 12/6/2006 Dear Colleague: So far, thyroid levels are too low here for a young dog. Are there any clinical signs ? Jean Adult Optimal Levels T4 2T3 50-150 ng/dl FT4 1-3 ng/dl FT3 3-8 pg/ml T4AA < 2.0 T3AA < 2.0 X Thyroid levels are below minimal expectations for a healthy performance adult (at least 1.5 X Thyroid levels are too low. Recommend 6-8 weeks of Soloxine® or equivalent product at 0.1mg per 12-15 lbs twice daily (e.g. 0. 15 – 0. 2 mg BID) is suggested, followed by retesting thyroid profile 4-6 hours post-pill to monitor response levels. Dose at optimum weight. X Optimal therapeutic response levels should be in the upper 1/3 to 25% above the upper limits of the resting optimal ranges at 4-6 hours post-BID thyroid medication. Page 1 PARTIAL 12/ 06/2006 10:11 AM