Fatema J Serajee, M.D. Pediatrician and Pediatric Neurologist, Children's Hospital of Michigan Published Articles: Original Observations in Referred Journals 1. Huq AHMM, Chugani DC, Hukku B, Serajee FJ. 2002. Evidence of Somatic Mosaicism in Sturge – Weber Syndrome. Neurology 59:780-781 2. Nabi R, Zhong H, Serajee FJ and Huq AHMM. 2003. No association between single nucleotide polymorphisms in DLX6 and Piccolo genes at 7q21-q22 and autism. Am J Med Genet; 119B:98-101 3. Zhong H, Serajee FJ, Nabi R and Huq AHMM. 2003. No association between the EN2 gene and autistic disorder. J Med Genet 40: e4 4. Serajee FJ, Zhong H, Nabi R and Huq AHMM. 2003. The metabotropic glutamate receptor 8 gene at 7q31: partial duplication and possible association with autism. J Med Genet; 40: e42 Page 1 5. Serajee FJ, Nabi R, Zhong H and Huq AHMM. 2003. Association of INPP1, PIK3CG and TSC2 gene variants with autistic disorder: implications for phosphatidylinositol signalling in autism. J Med Genet, 40: e119 6. Serajee FJ, Nabi R, Zhong H and Huq AHMM 2004. Polymorphisms in xenobiotic metabolism genes and autism. J Child Neurol 19:413 - 7 7. Nabi R, Serajee FJ, Chugani DC, Zhong H and Huq AHMM. 2004. Association of tryptophan 2,3 dioxygenase gene polymorphism with autism. Am J Med Genet, 125B (1):63-8 8. Serajee FJ, Zhong H and Mahbubul Huq AH 2004. Association of Reelin gene polymorphisms in autism. Genomics, 2006;87(1):75-83. 9. Cerghet M, Tapos D, Serajee FJ, and Huq AHM M (2008). Homozygous myotonic dystrophy with craniosynostosis. J Child Neurol; 23:930-3. 10. Serajee FJ, and Huq AHM M (2009). Association of Y chromosome haplotypes with autism. J child Neurology, J Child Neurol. 24:1258-61. 11.Serajee FJ, Sarnaik SA, Altinock D and Huq AHM M. Stroke in sickle cell disease J Pediatric Neurology (in press) ABSTRACTS 1. AHM Mahbubul Huq, Hailang Zhong, Rafiqun Nabi, Diane C Chugani, Fatema J Serajee. Evidence for an additional susceptibility region for autism on human chromosome 7q36. 31st Annual Meeting of the Child Neurology Society in October 9-12, 2002. Ann Neurol 2002; 52(3):S116. 2. Fatema J Serajee, Kipp Chillag, Michael A Nigro, AHM Mahbubul Huq. Novel mutation in MPZ (P0) gene associated with Dejerine-Sottas and congenital hypomyelination phenotypes in the same family. 31st Annual Meeting of the Child Neurology Society in October 9-12, 2002. Ann Neurol 2002; 52(3):S152. 3. Kevin Valentine, Fatema J Serajee, Kipp Chillag, June Ventimiglia, Michael A Nigro, AHM Mahbubul Huq. Biochemical markers and efficacy of the ketogenic diet treatment of refractory pediatric epilepsy. 31st Annual Meeting of the Child Neurology Society in October 9-12, 2002. Ann Neurol 2002; 52(3): S140. 4. Jiang Y, Fatema J Serajee, Harry T Chugani, and AHM Mahbubul Huq. Mitochondrial respiratory chain enzyme complex deficiencies: report of five unique cases. 31st Annual Meeting of the Child Neurology Society in October 9-12, 2002. Ann Neurol 2002; 52(3):S149. 5. Fatema J Serajee, Kipp Chillag, AHM Mahbubul Huq. Early onset olivopontocerebellar atrophies and hypoplasia: report of five unique cases. 31st Annual Meeting of the Child Neurology Society in October 9-12, 2002. Ann Neurol 2002; 52(3):S150. 6. AHM Mahbubul Huq, Diane C. Chugani, Fatema J Serajee. Somatic Mosaicism in Sturge -Weber Syndrome. 31st Annual Meeting of the Child Neurology Society in October 9-12, 2002. Ann Neurol 2002; 52(3):S123. 7. AHM Mahbubul Huq, Hailang Zhong, Rafiqun Nabi, Diane C Chugani, Fatema J Serajee. Serotonergic neurotransmission and autism: A genetic analysis. 31st Annual Meeting of the Child Neurology Society in October 9-12, 2002. Ann Neurol 2002; 52(3):S115. Page 2 8. Fatema J Serajee, Michael Mally, Diane C. Chugani and AHM Mahbubul Huq. Somatic Mosaicism in Sturge -Weber Syndrome. 52nd Annual Meeting of the American Society of Human Genetics, October 15-19, 2002 9. AHM Mahbubul Huq, Hailang Zhong, Rafiqun Nabi and Fatema J Serajee. Analysis of six candidate genes for autism on 7q. 52nd Annual Meeting of the American Society of Human Genetics, October 15-19, 2002 10.Rafiqun Nabi, Hailang Zhong, Diane C Chugani, Fatema J Serajee and AHM Mahbubul Huq. Analysis of five serotonin system genes in autism by association and linkage. 52nd Annual Meeting of the American Society of Human Genetics, October 15-19, 2002 11.Hailang Zhong, Fatema J Serajee, Rafiqun Nabi, and AHM Mahbubul Huq. Association of the metabotropic glutamate receptor 8 gene at 7q31 with quantitative traits in autism. 52nd Annual Meeting of the American Society of Human Genetics, October 15-19, 2002 12.AHM M Huq, Fatema J Serajee, Rafiqun Nabi, William E Watson, and Hailang Zhong. Candidate genes for autism on chromosome 7q. 55th Annual Meeting of the American Academy of Neurology, March 29-April 3, 2003 13.Huq AHMM, Serajee FJ, Nabi R, Zhong H and. Investigation of 40 positional and functional candidate genes for Autism. 32nd Annual Meeting of Child Neurology Society, 2003; Ann Neurol 2003; 54(7):S119] 14.Serajee FJ, Nabi R, Zhong H and Huq AHMM. Investigation of 40 positional and functional candidate genes for Autism. XIth World congress of Psychiatric Genetics, 2003; Am J Med Genet 2003; 122B(1):117 15.R Nabi, F J Serajee, H Zhong, and AHM M Huq. Association analyses of 50 candidate genes for autism from 7q21-36 region. 33rd Annual Meeting of Child Neurology Society, 2004; Ann Neurol 2004; 56(S8): 100. 16.F J Serajee, R Nabi, H Zhong, and AHMM Huq. Association of Reelin Gene Polymorphisms with Autism. 33rd Annual Meeting of Child Neurology Society, 2004; Ann Neurol 2004; 56(S8): 99. 17.F J Serajee, R Nabi, H Zhong, and AHMM Huq. Immunogenetic studies in autism: association with IL4R and ICAM5 genes. 33rd Annual Meeting of Child Neurology Society, 2004; Ann Neurol 2004; 56(S8): 101. 18.R Nabi, F J Serajee, H Zhong, and AHM M Huq. Serotonin neurotransmitter system in autism: association with HTR4, HTR6 and TDO2 polymorphisms. 33rd Annual Meeting of Child Neurology Society, 2004; Ann Neurol 2004; 56(S8): 99. 19.R Nabi, F J Serajee, H Zhong, and AHM M Huq. Genetics of phosphatidylinositol signaling in autism. 33rd Annual Meeting of Child Neurology Society, 2004; Ann Neurol 2004; 56(S8): 103. 20.F J Serajee, R Nabi, H Zhong, and AHM M Huq. Association of chromosome 15 GABA-A receptor subunit genes with autism. 33rd Annual Meeting of Child Neurology Society, 2004; Ann Neurol 2004; 56(S8): 103. 21.R Nabi, F J Serajee1, H Zhong, and AHM M Huq. Distribution and heritability of phenotypic traits in autism. 33rd Annual Meeting of Child Neurology Society, 2004; Ann Neurol 2004; 56(S8): 105. 22.R Nabi, F J Serajee, H Zhong, and AHM M Huq. Association analyses of EN2 gene in autism. 34th Annual Meeting of Child Neurology Society, 2005; Ann Neurol 2005; 58(S9): 108. Page 3 23.F J Serajee, R Nabi, H Zhong, and AHM M Huq. Association of mitochondrial aspartate/glutamate carrier SLC25A12 and SLC25A13 genes with autism. 34th Annual Meeting of Child Neurology Society, 2005; Ann Neurol 2005; 58(S9): 105. 24.F J Serajee, R Nabi, H Zhong, and AHM M Huq. Association of Y chromosome haplotypes with autism. 34th Annual Meeting of Child Neurology Society, 2005; Ann Neurol 2005; 58(S9): 82. 25.Fatema. J. Serajee, Hailang Zhong, AHM M Huq. Prevalence of common mitochondrial point mutations in autism. Platform presentation at the 10th International Child Neurology Congress, June 11-16, 2006, Montreal, Canada, Abstract 577 26.Fatema. J. Serajee, Hailang Zhong, AHM M Huq. Immunogenetic studies in autism. Platform presentation at the 10th International Child Neurology Congress, June 11-16, 2006, Montreal, Canada, Abstract A693 27.Fatema. J. Serajee, Hailang Zhong, AHM M Huq. Y Chromosome Effect in Autism. 60th Annual Meeting of the American Academy of Neurology, April 12 -April 19, 2008 (recipient of travel research award) 28. Fatema. J. Serajee, Hailang Zhong, AHM M Huq. Mitochondrial haplogroups in Autism. 60th Annual Meeting of the American Academy of Neurology, April 12 -April 19, 2008 29.Ridwan Alam, Fatema J. Serajee, AHM M Huq. Dose Response to Oxcarbazepine in Children with Newly Diagnosed Partial Epilepsy. 61st Annual Meeting of the American Academy of Neurology, April 25 – May 02, 2009 30.Huq Naznin Mahmood, Farhan Murshed, Fatema J. Serajee, AHM M Huq. Ketogenic Diet Treatment of Intractable Epilepsy. 61st Annual Meeting of the American Academy of Neurology, April 25 – May 02, 2009 31.Fatema J. Serajee, AHM M Huq. Genetic Association Studies of Immune Genes in Autism (recipient of travel research award). 61st Annual Meeting of the American Academy of Neurology, April 25 – May 02, 2009 32.Fatema J. Serajee, AHM M Huq. Metabolite testing in developmental delay. Abstract # 27, 38th annual meeting of Child Neurology Society, October 14-17, 2009; Annals of Neurology 66 (suppl 13): S106, 2009 33.Fatema J. Serajee, Huq F, Wu Y, AHM M Huq. A mitochondrial polymorphism reduces the risk of autism. Abstract 28, 38th annual meeting of Child Neurology Society, October 14-17, 2009; Annals of Neurology 66 (suppl 13): S106, 2009 34.Fatema J. Serajee, Elizabeth Leleszi, AHM M Huq. Oligogenic inheritance in a mitochondrial disorder. Abstract *22, 38th annual meeting of Child Neurology Society, October 14-17, 2009; Annals of Neurology 66 (suppl 13): S104, 2009 Page 4