CP Biology – Cell Cycle, Mitosis and Meiosis Syllabus Guide --with Objectives and Study Guide OBJECTIVE #1 Chromosomes and Their Structure Describe the structure of chromosomes. Know how DNA is organized with its associated proteins. Know the kinds and numbers of chromosomes in humans and generally in other organisms. Compare and contrast sex chromosomes and autosomes. Know the differences between haploid and diploid cells. Lesson Reading Homework Terms for Flashcards Assignment CHROMOSOMES Modern Biology: 8.1 Watch this: histones OR http://learnzillion.com/ non-histone proteins To Review: http://www.ck12.org/book/ lessons/1751-createchromatid http://yhoo.it/1cfRR3K Biology/r11/section/5.2/ an-outline-to-keepcentromere or (just the first four sections) track-of-what-yousex chromosomes http://bit.ly/MTvZiq OR read autosomes https://www.khanacademy. Now use this “boxes homologous chromosomes org/science/biology/celland bullets” method to homologues division/v/chromosomes-- take notes of what you karyotype chromatids--chromatin--etc read or watched. diploid (from 8:50 on) Be ready to use your haploid notes to answer chromosome questions in class. Can you: o Describe the structure of chromosomes. o Describe how DNA is organized with its associated proteins. o List the kinds and numbers of chromosomes in humans and generally in other organisms. o Compare and contrast sex chromosomes and autosomes. o Describe the differences between haploid and diploid cells. OBJECTIVE #2 The Cell Cycle Identify when and for what purpose cells divide. Describe how the cell cycle is organized. Lesson Reading Homework Terms for Flashcards Assignment CELL CYCLE Modern Biology: 8.2 (pages Use the “boxes and binary fission 148-149) bullets” method to take cell cycle To Review: OR notes of what you read or G0 phase http://yhoo.it/1gXmKa http://www.ck12.org/book/Biol watched. G1 phase C ogy/r11/section/5.1/ G2 phase Be ready to use your or OR mitosis notes to answer http://bit.ly/MTvZiq http://www.youtube.com/watch questions in class. M phase ?v=C6hn3sA0ip0 S phase (from 1:30 to 2:27) mitosis meiosis Can you: o Identify when and for what purpose cells divide. o Describe the phases of the cell cycle. OBJECTIVE #3 Mitosis Describe the process of mitosis including the events of each phase and the structures involved. Distinguish between the structures involved in plant and animal mitosis. Explain the role of mitosis in the formation of new cells, and its importance in maintaining chromosome number during asexual reproduction. Lesson Reading & Watching Assignments MITOSIS Modern Biology: 8.2, bottom of 149 to 151. To Review: OR http://www.biology.ariz http://www.ck12.org/book/Biolog ona.edu/cell_bio/activit y/r11/section/5.2/ ies/cell_cycle/cell_cycl (after the first four sections) e.html OR or http://www.bozemanscience.com/ http://bit.ly/MTvZiq mitosis OR http://www.youtube.com/watch?v =C6hn3sA0ip0 Homework Use the “boxes and bullets” method to take notes of what you read or watched. Be ready to use your notes to answer questions in class. Terms for Flashcards anaphase cell plate centriole centrosome cleavage furrow cytokinesis interphase kinetochore kinetochore fiber meiosis metaphase mitosis mitotic spindle polar fiber prophase spindle fiber telophase Can you: o List the phases of mitosis including the events of each phase and the structures involved. o Distinguish between the structures involved in plant and animal mitosis. o Explain what the purpose of mitosis is. o Describe why mitosis maintains chromosome number. OBJECTIVE #4 Meiosis List the events in the stages of meiosis. Describe how the process of meiosis results in the formation of haploid cells. Explain the importance of this process in sexual reproduction, and how gametes form diploid zygotes in the process of fertilization. Describe the additional function of the chromosome to increase genetic diversity through crossing over. Lesson Reading Homework Terms for Flashcards Assignment MEIOSIS Modern Biology: 8.3 Use the “boxes and asexual reproduction OR bullets” method to take crossing over To Review: http://www.ck12.org/book/Biolo notes of what you read gamete http://yhoo.it/1nmuHu gy/r11/section/5.3/ genetic recombination or watched. Be ready 7 OR independent assortment to use your notes to or http://www.bozemanscience.co oogenesis answer questions in http://bit.ly/MTvZiq m/meiosis polar body class. sexual reproduction spermatid spermatogenesis shynapsis tetrad Can you: o List the events in the stages of meiosis. o Describe how haploid cells are formed. o Explain how gametes form diploid zygotes in the process of fertilization. o Define independent assortment. o Describe the function and advantage of crossing over. CP Biology – Cell Cycle, Mitosis and Meiosis Study Guide From: http://biologyjunction.com/cell_division_notes.htm OBJECTIVE #1 Chromosomes and Their Structure The plans for making cells are coded in ____________________. ________________________________ is a long thin molecule that stores genetic information. DNA in a human cell is estimated to consist of _____________________ pairs of nucleotides. DNA is organized into giant molecules called __________________________________. Chromosomes are made of ______________ and a ____________molecule which is tightly coiled and visible only when the cell divides. When a cell is not dividing the DNA is less visible and is called ___________________. DNA in eukaryotic cells wraps tightly around proteins called ______________________ to help pack the DNA during cell division. ________________________ proteins help control the activity of specific DNA genes. ______________________ hold duplicated chromosomes together before they are separated in mitosis. _____________________________are the ends of chromosomes which are important in cell aging When DNA makes copies of itself before cell division, each half of the chromosome is called a _____________________________________. DNA of ________________ (bacteria) is one, _____________ chromosome attached to the inside of the cell membrane. Humans _____________ cells have _____ pairs of chromosomes or 46 chromosomes (diploid or 2n number). Homologous chromosomes have genes that code for the same _____________ but are not ________________. Human __________________(sperms & eggs) have one set or _____ chromosomes (haploid or 1n number). Every organism has a specific chromosome __________________. (see chart for a hint) Organism Chromosome Number (2n) Human 46 Fruit fly 8 Lettuce 14 Goldfish 94 ___________ chromosomes, either X or Y, determine the sex of the organism. Two X chromosomes, XX, will be ___________ and XY will be ______________. All other chromosomes, except X & Y, are called ___________________. Chromosomes from a cell may be arranged in pairs by size starting with the longest pair and ending with the sex chromosomes to make a ___________________. A human karyotype has 22 pairs of _________________ and 1 pair of ___________ chromosomes (23 total). OBJECTIVE #2 The Cell Cycle Identify when and for what purpose cells divide. Describe how the cell cycle is organized. All cells are derived from ______________ cells (Cell Theory). C___________ d___________ is the process by which cells produce new cells. Cell division differs in prokaryotes (bacteria) and eukaryotes (protists, fungi, plants, & animals) Prokaryotes perform one type of cell division: __________ fission, where genetic material is segregated equally between two daughter cells. Eukaryotes perform two types of cell division: ______________: in which the number of chromosomes in the daughter cells is the same as in the parent cell. ______________: in which the number of chromosomes in the daughter cells is half the number in the parent cell. The reasons for cell division are for: Cell _________________, ___________ and ________________ of damaged cell parts, ___________________ of the species Some tissues must be repaired often such as the lining of gut, white blood cells, skin cells with a short lifespan. So cells in these tissues divide _________________. Other tissue cells do not divide at all after birth (such as ________________). Since the instructions for making cell parts are encoded in the DNA, each new cell must get a __________________ set of the DNA molecules. This requires that the DNA be ___________________ before cell division. Cell division includes both ______________ (the division of the nucleus) and cytokinesis (the division of the ________________). Cells go through a _________ ___________ during their life before they divide to form new cells The cell cycle includes 2 main parts --- _________, and __________. _____________ is the longest part of a cell's life cycle and is called the ____________ ________ because the cell isn't dividing Cells grow, develop, & carry on all their normal metabolic functions during _________________. Interphase consists of 3 parts --- ___, ____, and ______ phases G1 occurs _______ a cell has undergone cell division Cells mature & increase in size by making more __________ and _________ while carrying normal metabolic activities in G1 S Phase follows G1 and the genetic material of the cell (DNA) is _________________. G2 occurs _________ S Phase and the cell makes all the structures needed to _____________. Prokaryotes such as bacteria do not have a __________. Prokaryotes divide into two identical new cells by the process of ___________ ___________. Binary fission is an ___________ method of reproduction Eukaryotes have a ___________ and ___________organelles which must be copied exactly so the _______ new cells formed from division will be exactly alike The original ____________ cell and the resulting two new daughter cells must have ___________ chromosomes Both the nucleus (__________) and the ___________ (cytokinesis) must be divided during cell division in eukaryotes OBJECTIVE #3 Mitosis Describe the process of mitosis including the events of each phase and the structures involved. Distinguish between the structures involved in plant and animal mitosis. Explain the role of mitosis in the formation of new cells, and its importance in maintaining chromosome number during asexual reproduction. Stages of Mitosis: Division of the ______________ or mitosis occurs first Mitosis is an ______________ method of reproduction Mitosis consists of 4 stages --- P_______________, M______________, A____________, & T__________ Prophase: Metaphase: Anaphase: Telophase: Cytokinesis: Cancer is Uncontrolled Mitosis: Mitosis must be ________________, otherwise growth will occur without limit (cancer) Control is by special ___________________ produced by oncogenes ___________________ in control proteins can cause cancer ____________________ proteins bind to centromere and attach chromosome to the spindle in mitosis. The centrosomes of plant cells lack _____________. A ________________ _______________ divides an animal cell into two during cytokinesis. Plant cells are divided during cytokinesis by the growing _____________________. OBJECTIVE #4 Meiosis List the events in the stages of meiosis. Describe how the process of meiosis results in the formation of haploid cells. Explain the importance of this process in sexual reproduction, and how gametes form diploid zygotes in the process of fertilization. Describe the additional function of the chromosome to increase genetic diversity through crossing over. Fertilization, joining of the egg & sperm, restores the _____________ chromosome number in the zygote (fertilized egg cell) New cells have a single copy of chromosomes (23 total in humans) but are not identical to each other or the original parent cell Used for making _______________ ( sperm and eggs) with the haploid or n number In meiosis, cells divide _____________ after a single DNA duplication Meiosis I separates ________________ & the Meiosis II separates ___________ _______________ Meiosis I stages are Prophase I, Metaphase I, Anaphase I, & Telophase I Meiosis II stages are Prophase II, Metaphase II, Anaphase II, & Telophase II Produces _______haploid cells or gametes When a sperm fertilizes an egg to form a zygote, the diploid number of chromosomes is restored (23 + 23 = 46 in humans) Egg cells or ova (ovum, singular) are larger , ______________ cells Gametoogenesis is __________________ producing eggs & occurs in the female's ovaries Sperms contain less _______________ so they're smaller & have a flagellum to swim to the egg _________________________ is meiosis producing sperm cells & occurs in the testes Meiosis I: The cell that undergoes Meiosis I is a primary spermatocyte or oocyte Prophase I: Metaphase I: Anaphase I: Telophase I: Meiosis II Prophase II: o Cells called Secondary Spermatocytes or oocytes o DNA is not copied before cell divides o Chromatids attach to spindle fiber Metaphase II: Anaphase II: o Sister chromatids separate randomly o Called ____________________assortment Telophase II: o Cytokinesis occurs producing _______cells in males called spermatids o Spermatids mature & form flagellum to become sperm o Cytokinesis in females produces a 2nd Polar Body that dies and an _________ o Ootids mature to become _____________ Asexual & Sexual reproduction: ________________ is the slow process of change in living populations over time Variations are differences that occur due to __________________among members of a sexually reproducing population Variations are important to the ________________ of individuals in a population (some must survive to reproduce) ____________________ reproducing organisms rarely show variations because the organisms have identical genes