Curriculum Vitae of CHEE LOONG SAW Education 1998 - 2001 : Instrumentation and Analytical Sciences, PhD, University of Manchester, England. Thesis Advisor : Prof. P A Payne, Prof. R J Dewhurst Post-Doctoral Training 2006 – 2008 : Post doctoral fellow, Department of Pathology, Emory University Hospital 2003 – 2005: Post doctoral fellow, TzuChi Marrow Donor Registry, Taiwan 2001 – 2003: Post doctoral fellow, Institute of Biochemistry and Genetics, University of Basel, and Basel Cantonal Hospital, Switzerland. Positions and Appointments 2008/6 – present : TRALI Working Group Consultant, Canadian Blood Services, Canada. 2008/6 – present : Scientific Director, Platelet and Neutrophil Immunology Laboratory, Canadian Blood Services, Winnipeg, Canada. 2006/01 – 2008/5 : Director-in-Training / fellow at Emory University Hospital, Atlanta, Georgia. 2003/08 – 2005/12 : Fellow at Tzu Chi General Hospital, Hualien, Taiwan at Immunogenetics Laboratory (major laboratory) for TzuChi Marrow Donor Registry, and Virus Laboratory. 2001/09 – 2003/06 : Fellow at NCCR Nanotechnology in Medicine, collaborator between Physical Chemistry Department, University Hospital and Institute of Biochemistry and Genetics. 2001/02 – 2001/03 : Intern at Fraunhofer Institute of Biomedical Engineering, St. Ingbert, Germany. Clinical Experience (Grants Coordinator/Project Consultant) 1) Clinical Trials in Organ Transplantation (CTOT-1), Noninvasive Monitoring to Predict Outcome in De Novo Kidney Transplant Recipients. Sponsor : NIAID 2) Immune Tolerance Network (ITN), Identification and mechanistic investigations of tolerant kidney, Alloantibody and flow crossmatch Core. 3) Industrial grants from BMS Clinical Trial Five projects, recruiting some 2000 patients from 5 centers (USA, Europe, South Africa, South America, Asia Pacific), HLA Alloantibody Profiling. Awards 2001/02 – 2001/03 Deutscher Akademischer Austauschdienst (DAAD German Academic Exchange) Junior Scientist Awards, and Alumni Membership (at Fraunhofer Institute) 1998/09 – 2001/09 National Heart Research Fund, Leeds, UK for PhD research Publications : (A) Papers and Book Chapters (1) CL Saw, HM Gebel, RA Bray, Differential expression of HLA Class I on B cell subsets, 2007 (in preparation). (2) CL Saw, RA Bray, HM Gebel, Cytotoxicity and antibody binding by flow cytometry : A single assay to simultaneously assess two parameters, Clinical Cytometry B, 2008 September, 75(5); 287-94. (3) CL Saw, D Heaney, RA Bray, HM Gebel, Relevance of Antibody Screening and Crossmatching in Solid Organ, Hematopoietic Stem Cells Transplantation and Blood Transfusion, Handbook of Human Immunology (Ed. By Mary Leffell et al), CRC Press, 2007. (4) P Broz, S Benito, CL Saw et al, Cell targeting by a generic receptor-targeted polymer nanocontainer platform, Journal of Controlled Release, 2005 February, 102; 2, 475-488. (5) P Broz, S Benito, CL Saw, et al, Receptor-programmable polymer nanocontainers: A novel targeting system for the vulnerable plaque, Brief communication, Circulation 2004 AHA No. 2004/441253, 2004 September. (6) PA Payne, CL Saw, K Roome, J Hatfield, R Dewhurst, Towards an intra-arterial probe for imaging and therapy using laser-generated ultrasound, Acoustical Imaging, Springer Publisher, 2006, 177-182. 978-0-306-46516-1 (Print) 978-0-306-47107-0 (Online) (7) P Hunziker et al, Nanotechnology in Medicine : Moving from the bench to the Bedside, CHIMIA 2002, 56, No 10, 520-526. (contribution towards paper) (B) Conference Proceedings (1) CL Saw, RA Bray, DL Heaney, HM Gebel, Cytotoxicity and antibody binding by flow cytometry : one assay to assess two parameters, 33rd ASHI Annual Meeting, Minneapolis, 2007, Human Immunology, 68, S1, 117. (2) P Brannon, DL Heaney, CL Saw et al, Improved detection of HLA antibodies by LABSCREEN® Single Antigen using a biotin-streptavidin complex system, 33rd ASHI Annual Meeting, Minneapolis, 2007, Human Immunology, 68, S1, 21. (3) HM Gebel, CL Saw, DL Heaney, RA Bray, A simple solution to a complex situation, (Ed. PI Terasaki). Advanced Histocompatibility Workshop, Cancun, Mexico, 2007. (4) RA Bray, P Brannon, CL Saw et al, Improved detection of HLA antibody by Labscreen® using biotin-streptavidin complex system, (Ed. PI Terasaki). Advanced Histocompatibility Workshop, Cancun, Mexico, 2007. (5) CL Saw, RA Bray, HM Gebel, Differential expression of HLA Class I on B cell subsets, 32nd ASHI Annual Meeting, San Diego, 2006, Human Immunology, 67, S1, 1. (6) TD Lee, HH Huang, CL Saw, et al, High throughput bead chip HLA genotyping of asian bone marrow donors, 19th European Immunogenetics and Histocompatibility Conference, Istanbul, Turkey, 23-26 April 2005, Genes and Immunity, 6, S53. (7) YF Chen, CL Saw, et al, Characterization of thin film formation on electrochemical biosensor for SARS virus detection, 1st International Conference on Nanotechnology, Singapore, 2004 July. (8) S Benito, P Broz, CL Saw, et al, Functionalised ABA triblock copolymer nanocontainers for active drug delivery, 141th Annual Meeting 2003: Second Joint French - Swiss Meeting on Medicinal Chemistry, Beaune, July 1-4, 2003, (the Swiss Chemical Society Poster Prize). (9) P Broz, CL Saw, et al, Targeting the vulnerable plaque : a task for nanocontainer ? Gemeinsame Jahrestagung der Schweiz. Gesellschaften für Kardiologie; Thorax-, Herz-, und Gefässchirurgie; Intensivmedizin, 2003 May. (10) S Benito, S Graff, CL Saw, et al, Functionalized Nanocontainers for Drug Delivery, 7. Nachwuchstage der Kolloid- und Grenzflächenforschung, Heidelberg, Germany, 2003 May. (11) CL Saw, P Hunziker, et al, Nanocontainer Drug-targeting : Binding and cellular handling, NCCR Nanoscience Workshop, Nanotechnology in Medicine, Pontresina, GR, Switzerland. 2002 September. (12) CL Saw, PA Payne, R Dewhurst, Towards an intra-arterial probe for imaging and therapy using laser-generated ultrasound, 25th International Acoustical Imaging Symposium, Bristol, UK. 2000 March.