1 CURRICULUM VITAE 1. PERSONAL DETAILS Name: Date of birth: Citizenship: Marital status: Telephone: Fax: E-mail address: Marjukka Kolehmainen (os. Tiainen) January 15th, 1968 Finnish Married; two children (born 2002 and 2004) 017 163 617 (work), 040 539 7922 (mobile) 017 162 785 marjukka.kolehmainen@uku.fi 2. QUALIFICATIONS 2003, University of Kuopio, Department of Clinical Nutrition Doctor of philosophy (PhD), Topic: Metabolic studies on adipose tissue in severe obesity (May 10th academic dissertation, May 27th doctoral degree), special degrees are not given 1995, Terveydenhuollon oikeusturvakeskus, Authorized nutritionist 1993, University of Kuopio, Department of Clinical Nutrition, Master of Science in clinical nutrition, Topic: Diet and nutritional status in children with cow's milk allergy, graduated with 'Laudatur'-degree 3. EXPERIENCE University of Kuopio, Food and Health Research Centre/Department of Clinical Nutrition: - Consortium Manager & Scientific secretary of Nordic Centre of Excellence (NCoE) on Systems biology in controlled dietary interventions and cohort studies (SYSDIET), May 1st, 2007- Finnish Academy Post doctoral researcher April 1st 2005 - 31st July 2008 - Senior researcher, November 1st 2004- Project manager, researcher January 11th 2003-October 30th 2004 - Researcher responsible of plans for ‘Obesity research unit’, maternity leave February 25th, 2002-January 10th, 2003 - Researcher responsible of plans for ‘Obesity research unit’, March 1st, 2001-February 24th, 2002 University of Kuopio, Department of Clinical Nutrition: - PhD-student in Kuopio doctoral program of medical sciences, January 1st,1999February 28th, 2001 INSERM Unit 449, Faculté de Médecine, R.T.H. Laennec, Lyon, France, Dr. Hubert Vidal’s research group : - adipose tissue gene expression (mRNA) in severely obese subjects ; methodology and analysis of samples using reverse transcriptase competetive polymarese chain reaction, August 28th – November 26th, 2000 - training for using reverse transcriptase competetive polymarese chain reaction – methodology in gene expression (mRNA) analysis in adipose tissue, first analysis, February 8th-March 25th, 1999. University of Kuopio, Department of Clinical Nutrition, studying adipose tissue metabolism in severely obese subjects: - part time March 1st, 2001-May 10th, 2003 - PhD-student January 1st, 1995-February 28th, 2001, including various smaller clinical interventions University of Kuopio, Department of Clinical Nutrition: 2 - research assistant/ nutritionist in clinical intervention for testing pharmacological agent meant for weight reduction (Hoffman-La Roche), August 8th, 1993-December 31st, 1994 4. RESEARCH FUNDING Nordforsk Nordic Centre of Excellence (NCoE) on Systems biology in controlled dietary interventions and cohort studies (SYSDIET), 1.5.2007 - 31.12.2011, writing of application, consortium manager & scientific secretary Finnish Academy, 1.5.2005- 30.4.2008, Postdoctoral studies in Changes in gene expression in adipose tissue after long-term life-style intervention – the Genobin- and Fungenut-study Finnish Funding Agency for Technology and Innovation, 1.1.2003-31.12.2005, functional genomics and nutritional factors - the Fungenut study group Kuopio Doctoral Program of Medical Sciences, January 1st,1999-February 28th, 2001 Doctoral program in Applied bioscience – Bioengineering, Food and Nutrition, Environment, January 1st- June 30th,1995 (temporary post during a maternity leave) 5. GRANTS Yrjö Jahnsson Foundation, 2006: 25 000 € for studying the interaction of dietary and genetic factors in adipose tissue of subjects with metabolic syndrome Juho Vainio Foundation, 2003: 10 000 € for Affymetrix application used in ‘Functional Genomics and Nutritional Factors’-project Finnish Cultural Foundation of Northern Savo, 2003: 6 000 € for applying and setting up quantitative PCR methodology for the analysis of human adipose tissue gene expression Saastamoinen Foundation, 2000: 30 000 FIM for traveling and personal costs and the laboratory work in Dr.Hubert Vidal’s laboratory, France Jenny and Antti Wihuri Foundation, 1996: 50 000 FIM for PhD studies in 'Adipose tissue metabolism in severely obese subjects' 6. SUPERVISED ACADEMIC THESIS Doctor of Philosophy: Mager Ursula: The role of ghrelin in obesity and insulin resistance (May, 2008) Currently supervising, PhD-students: Jenni Lappi: Short and long term mechanisms underlying the health effects caused by consumption of whole grain foods, Maija Vaittinen: Functional studies of genes responsive to weight reduction, Lappalainen Tiina: Effect of lifestyle changes on genetic factors regulating lipid and glucose metabolism, Tolppanen Anna-Maija: Role of tenomodulin in fat tissue and development of type 3 diabetes, Siitonen Niina: Genes encoding 2B-adrenergic receptor, adiponectin and adiponectin receptors as candidate genes for type 2 diabetes and obesity, Salopuro Titta: Interaction of life style interventions and genes on insulin resistance and conversion to type 2 diabetes, Kallio Petteri: Effects of dietary carbohydrate modification on glucose metabolism and gene expression in adipose tissue applying nutrigenomics methodology, Master in science: Anne Riikonen (2008): The effect of berry diet on lipid metabolism in subjects with features of metabolic syndrome (Finnish), Suvi Heinonen (2008): The effects of berry diet 3 on glucose metabolism in subjects with features of metabolic syndrome (Finnish), Jenni Lappi(2008): The factors having an effect on the posprandial glucose and insulin responses of breads in persons with insulin resistance (Finnish), Uski Virpi (2006): Effect of weight reduction on glucose-insulin- and lipid-metabolism and relevant gene expression (Finnish). Ilomäki Heidi (2003): Effect of weight reduction on substrate utilization at rest and during exercise (English), Mursu Jaakko (2000): Effect of physical exercise on weight maintenance after weight reduction program (Finnish), Virtanen Jyrki (2000): Effect of creatine supplementation on exercise performance and body composition (English), Männistö Kirsi (1999): Sufficiency of food labeling in in compilling the diet of food allergic children (Finnish), Turtola Kati (1999): Effect of resistance or aerobic training on weight maintenance in Finnish men (Finnish), Ruottinen Soile (1997): Follow-up study of children with cow’s milk allergy (Finnish). Currently supervising, Master’s students: Katja Mäkelä: Effect of dietary modification on serum lipid and lipoprotein concentrations and their association to inflammation markers in subjects with insulin resistance, Anu Hongisto: Effect of dietary modification on glucose metabolism, insulin sensitivity, adiponectin and ghrelin in subjects with insulin resistance. 7. REFEREE DUTIES Journal of Cereal Science 2007, European Journal of Obstetrics & Gynecology and Reproductive Biology, January 2006, Journal of Clinical Endocrinology and Metabolism, January 2004, Diabetes Research and Clinical Practice, January, 2003 8. INVITED SPEECHES C&E Spring Meeting 2007, 2.-3.5.2007, Montpellier, France: Effects of cereal foods on glucose and insulin metabolism - a Nutrigenomics approach Dietary Fibre 2006, Multifunctional Complex of Components, 12.-14.6.2006, Finland, Helsinki: Nutrigenomics approach to study effects of cereals on glucose and insulin metabolism ICC Jubilee Conference 2005, July 3rd – 6th, Vienna, Austria: Nutrigenomics approach to study effects of cereals on glucose and insulin metabolism. Functional Foods; Course organized by Graduate School for Applied Biosciences, Helsinkin 1.9.2004: Nutrigenomics Chemistry days 2003, Helsinki: Uudet molekyylibiologian menetelmät ravitsemustutkimuksessa. .