SBRT Implementation, UF Experience and Outcome
時
間：2014 年 04 月 18 日(五) 18:00~20:00
地
點：高雄醫學大學附設中和紀念醫院 啟川大樓 6 樓 第一會議室
高雄市三民區自由一路 100 號
講
師：Chihray Liu, PhD
Professor and Chief Physicist,
Department of Radiation Oncology, University of Florida
活動內容：
18:00 – 18:30 Registration & Dinner Reception
18:30 – 19:40 Lecture – SBRT Implementation, UF Experience & Outcome
19:40 – 20:00 Open Discussion
演講簡介：
Stereotactic Body Radiation Therapy 為目前國際放射治療技術之發展趨勢，本
次演講邀請劉智睿博士分享 University of Florida 放射腫瘤治療中心觀察臨床
SBRT 的研究經驗分享，以作為國內放射腫瘤治療研究發展參考。
Email: liucr@shands.ufl.ed
Address: 2000 Archer Rd. Room 1222, PO Box 100385, Gaineseville, FL 3261
Office Phone: (352) 265-8217
Chihray Liu, PhD
Professor and Chief Physicist
Specialties
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Clinical radiation physics
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Enhanced dynamic wedge
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Dynamic MLC
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Conformal therapy
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IMRT
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Dose calculation and machine output calculation
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Computer modeling of dynamic therapy treatment using multileaf collimator
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Computerized routine treatment procedures
Educational Background
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PhD, Physics, University of Nebraska-Lincoln
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MS, Physics, University of Nebraska-Lincoln
Professional Societies and Committees
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American Association of Physicists in Medicine (AAPM)
Honors and Awards
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Sigma Xi Travel Grant Award, 1988
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National Science Foundation Fellowship, Taiwan, Republic of China, 1979
Publications
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Peng J.L., Kahler D., Li J., Samant S., Yan G., Amdur R., Liu C. Characterization of a real-time surface
image-guided stereotactic positioning system. Med Phys. 2010 Oct; 37(10): 5421-33.
Simon T., Kozelka J., Simon W., Kahler D., Li J., Liu C. Characterization of a multi-axis ion chamber
array. Med Phys. 2010 Nov; 37(10): 6101-11.
Peng JL, Kahler D, Li JG, Samant S, Yan G, Amdur R, Liu C. Characterization of a real-time surface
image-guided stereotactic positioning system. Med Phys. 2010 Oct;37(10):5421-33.
Simon T., Simon W., Kahler D., Li J., Liu C.Wide field array calibration dependence on the stability of
measured dose distributions.Med Phys. 2010 Jul; 37(7):3501-9.
Peng L. Kahler D., Samant S., Li J., Amdur R., Palta J.R., Liu C. Quality assessment of frameless
fractionated stereotactic radiotherapy using cone beam computed tomography. Int J Radiat Oncol Biol
Phys. 2010 December 1;78(5): 1586-1593.
Shi W, Liu C, Lu B, Yeung A, Newlin HE, Amdur RJ, Olivier KR. The effect of intravenous contrast on
photon radiation therapy dose calculations for lung cancer. Am J Clin Oncol. 2010 Apr;33(2):153-6.
Yeung AR, Li JG, Shi W, Newlin HE, Chvetsov A, Liu C, Palta JR, Olivier K. Tumor localization using
cone-beam CT reduces setup margins in conventionally fractionated radiotherapy for lung tumors. Int J
Radiat Oncol Biol Phys. 2009 Jul 15; 74(4):1100-7.
Yeung AR, Li J, Shi W, Newlin H, Morris CG, Samant S, Saito A, Chvetsov A, Liu C, Palta J, Olivier K.
Optimal image-guidance scenario with cone-beam computed tomography in conventionally fractionated
radiotherapy for lung tumors. Am J Clin Oncol. 2010 Jun; 33(3):276-80.
Fox C, Simon T, Simon B, Dempsey JF, Kahler D, Palta JR, Yan G. and Liu CAssessment of the setup
dependence of detector response functions for mega-voltage linear accelerators. Med Phys. 2010 Feb;
37(2):477-84.
Yan G, Lu B, Kozelka J, Liu C, and Li JG. Calibration of a novel 4D diode array. Med Phys 2010 Jan;
37(1):108-15.
Amdur R., Bennett J., Olivier K., Wallace A., Morris, C. G., Liu C., Mendenhall W. M. A Prospective,
Phase II Study Demonstrating the Potential Value and Limitation of Radiosurgery for Spine Metastases.
Am J Clin Oncol. 2009 Oct;32(5):515-520
Simon T, Kahler D, Simon W, Fox C, Li J, Palta J, and Liu C. An MLC calibration method using a
detector array. Medical Physics. 36:4495-4503 October 2009.
Simon T, Kahler D, Simon W, Fox C, Li J, Palta J, and Liu C. An MLC calibration method using a
detector array. Medical Physics. 36:4495-4503 October 2009.
Li JG, Yan G, and Liu C. Comparison of two commercial detector arrays for IMRT quality
assurance. Journal of Applied Clinical Medical Physics. 10:62-74, May 2009.
Saito AI, Li JG, Liu C, Olivier KR, and Dempsey JF. Accurate heterogeneous dose calculation for lung
cancer patients without high-resolution CT densities. Journal of Applied Clinical Medical Physics.
10:92-103, May 2009.
Yeung AR, Li JG, Shi W, Newlin H, Chvetsov A, Liu C, Palta J, and Olivier K. Tumor localization using
cone-beam CT reduces setup margins in conventionally fractionated radiotherapy for lung tumors.
International Journal of Radiation Oncology, Biology, Physics. 74:1100-1107, July 2009.
Yan G, Liu C, Simon TA, Peng L-C, Fox C, and Li JG. On the sensitivity of patient-specific IMRT QA
to MLC positioning errors.Journal of Applied Clinical Medical Physics. 10:120-128, February 2009.
Yan G, Fox C, Liu C, and Li JG. The extraction of true profiles for TPS commissioning and its impact on
IMRT patient-specific QA. Med Phys. 35:3661-3670, August 2008.
Song WY, Kamath S, Ozawa S, Alani S, Chvetsov A, Bhandare N, Palta J, Liu C,and Li JG. A Dose
Comparison Study between XVI and OBI CBCT Systems. Med Phys. 35:480-486, 2008.
Yan G, Liu C, Lu B, Palta JR, Li JG. Comparison of analytic source models for head scatter factor
calculation and planar dose calculation for IMRT. Phys Med and Biol. 53:2051-2067, April 2008.
Palta JR, Liu C, Li JG. Current External Beam Radiation Therapy Quality Assurance Guidance: Does It
Meet the Challenges of Emerging Image-Guided Technologies? Int J Radiat Oncol, Biol, Phys. 71: 13-17,
2008.
Palta JR, Liu C, Li JG. Quality Assurance of Intensity-Modulated Radiation Therapy. Int J Radiat Oncol,
Biol, Phys. 71: 108-112, 2008.
Liu C, Simon TA, Fox C, Li J, Palta JR. Multileaf Collimator Characteristics and Reliability
Requirements for IMRT Elekta System. Int J Radiat Oncol, Biol, Phys. 71: 89-92, 2008.
Amdur RJ, Liu C, Li J, Mendenhall W, Hinerman R. Matching Intensity-Modulated Radiation Therapy to
an Anterior Low Neck Field. Int J Radiat Oncol, Biol, Phys. 69: 46-48,2007.
Chang DT, Olivier KR, Morris CG, Liu C, Dempsey JF, Benda RK, Palta JR. The Impact Of
Heterogeneity Correction On Dosimetric Parameters That Predict For Radiation Pneumonitis. Int J Radiat
Oncol, Biol, Phys. 65: 125-131, 2006 .
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Li JG, Liu C, Kim S, Amdur RJ, and Palta JR. Match IMRT Fields with Static Photon Field in the
Treatment of Head and Neck Cancer. Med Dosim. Volume 30, Issue 3, Autumn 2005, Pages 135-138.
Jin H, Chung H, Liu C, Palta J, Suh TS, and Kim S. A Novel Dose Uncertainty Model And Its
Application For Dose Verification. Med Phys. 32, 1747 (2005).
Chung H, Jin H, Dempsey JF, Liu C, Palta J, Suh TS, and Kim S. Evaluation of Surface and Build-Up
Region Dose for Intensity-Modulated Radiation Therapy in Head and Neck Cancer. Med Phys. 32, 2682
(2005).
Kim S, Akpati HC, Li JG, Liu CR, Amdur RJ, and Palta JR. An immobilization system for
claustrophobic patients in head and neck intensity-modulated radiation therapy. Int J Radiat Oncol, Biol,
Phys. 59: 1531-1539, 2004. (August).
Kim S, Akpati HC, Kielbasa JE, Li JG, Liu CR, Amdur RJ, and Palta JR. Evaluation of intrafraction
patient movement for CNS and head and neck IMRT. Med Phys. 31(3), 500-506, 2004.
Amdur RJ, Li J, Liu C, Hinerman RW, and Mendenhall WM. Unnecessary Larynx Irradiation in the
IMRT Era. Head Neck. 2004 Mar; 26(3):257-64.
Li JG, Dempsey JF, Ding L, Liu C, and Palta JR. Validation of Dynamic MLC-Controller Log Files
Using a Two-Dimensional Diode Array. Med Phys. 30(5), 799-805, 2003.
Bahmaid M, Kim S, Liu C, Palta JR. Dosimetric Characteristics of Thermo–Shield Materialfor
Orthovoltage Photon Beams. Med Phys. 30(6), 1000-1003, 2003.
Liu C, Kim S, Kahler DL, and Palta JR. Generalized Monitor Unit Calculation for the Varian Enhanced
Dynamic Wedge Field.Med Phys. 30(7), 1891-1896, 2003.
Ma C-M, Chair, Coffey CW, DeWerd LA, Liu C, Nath R, Seltzer SM, and Seuntjens JP. AAPM protocol
for 40–300 kV x-ray beam dosimetry in radiotherapy and radiobiology.Med Phys. 28 (6),868-893, 2001.
Kim S, Liu C, and Palta JR. Two Effective Source Method For The Calculation Of In Air Output
Factors. Med Phys. 26 (6),949-955, 1999.
Liu C, Li Z, and Palta JR. QC in virtual simulation for 3-d radiation therapy. Adv for Admin in Radio &
Rad Onc. V8 N5, 35-40, 1998.
Kim S, Liu C, Zhu TC, and Palta JR. Photon beam skin dose analysis for different clinical setup. Med
Phys. 25(6), 860-866, 1998.
Li Z, Mitchell TP, Palta JR, and Liu C. A quality assurance test tool for high dose-rate remote
afterloading brachytherapy units. Med Phys. 25 (2), 232-235, 1998.
Liu C, Li Z, and Palta JR. Characterizing output for the Varian enhanced dynamic wedge field. Med Phys.
26(1), 64-70, 1998.
Li Z, Liu C, and Palta JR. Optimized dose distribution of a high dose rate vaginal cylinder. Int. J. Radiat.
Oncol. Biol. Phys. 41, 29-244, 1997.
Zhu T.C., Ding L., Liu C., and Palta J.R.: Performance evaluation of a diode array for enhanced dynamic
wedge dosimetry. Med Phys. 24(7),1173-1180, 1997.
Bova FJ, Buatti JM, Friedman WA, Yang C, and Liu C. The University of Florida frameless
high-precision stereotactic radiotherapy system. Int J Radiat Oncol Biol Phys. 38, 875-882, 1997.
Liu CR, Waugh B, Li Z, Zhu TR, and Palta JR. Commissioning the enhanced dynamic wedge on a
ROCS RTP system. Med Dosim. V22, 231-236, 1997.
Liu CR, Zhu TC, and Palta JR. Characterizing output for dynamic wedge.Med Phys. 23, 1213 1218,
1996.
Komanduri A, Saw C, and Liu C. Optimization of catheters and seeds for I-125 brain
implants. Proceedings of the XIth International Conference on the Use of Computers in Radiation
Therapy. 310-311, 1994.
Liu CR, Gao B, and Starace AF. Variationally stable treatment of two- and three-photon detachment of
H- including electron correlation effects. Phys Rev A.1992.
Waterman FW, Tupchong L, Liu CR.Modified thermal clearance technique for determination of blood
flow during local hyperthermia. Int J Hyperthermia. 7: 719-733, 1991.
Liu CR, Du NY, and Starace AF. One and two-photon detachment of H- with excitation of H (n=2). Phys
Rev A. 43: 5891, 1991.
Liu CR and Starace AF. Low-energy features of the e–H (n=2) system exhibited in fast H- detachment
collisions. Phys Rev Lett. 62: 407, 1989.
Liu C.R. and Starace AF. Doubly differential cross section for fast H– rare gas collisions. Phys. Rev. A
42: 2684, 1990.
Gao B, Pan C, Liu CR, and Starace AF. Variational methods for high-order multiphoton processes. J Opt
Soc Am B 7: 622, 1990.
Liu CR and Starace AF. Doubly differential detachment cross section for 0.5 MeV H- on He including
projectile excitation to H (n=2).Phys Rev A. 40: 4926, 1989.
Liu CR and Starace AF. Atomic hydrogen in a uniform magnetic field: low-lying energy levels for fields
above 109 G. Phys Rev A.35: 647, 1987.