NPC Progress Meeting in collaboration with PRIME-XS 26 & 27 January 2015 Media Plaza (Jaarbeurs Utrecht) I Croeselaan 6 I 3521 CA I Utrecht Monday 26 January 09:00-09:30 Coffee & Tea Flame Foyer 09:30-09:45 Welcome by Albert Heck Scientific Director NPC Polar 09:45-10:15 Deciphering receptor tyrosine kinase signaling by functional proteomics Jesper Velgaard Olsen University of Copenhagen, The Novo Nordisk Foundation, Center for Protein Research 10:15-10:45 A quantitative proteomics tool to identify DNA-protein interactions in primary cells or blood Nina Hubner Institute for Molecular Life Sciences, Radboud UMC 10:45-11:15 The Cathedral and the Bazaar: crowd-sourcing proteomes Lennart Martens Ghent University, VIB Department of Medical Protein Research Polar 11:15-11:45 Coffee Break Flame Foyer 11:45-12:45 Parallel sessions Polar 1. Vital statistic or postmortem? Quality control in proteomics Bas van Breukelen (UU) & Lennart Martens (VIB) Spark 2. ULTRA-HIGH-FIELD Orbitrap: Advantages for Proteomics and Data Independent Acquisition Claire Dauly (Thermo Scientific) Flash 3. Biophysical analysis of molecular interactions with electro-switchable biosurfaces: switchSENSE Ulrich Rant (Dynamic Biosensors) 12:45-14:00 Lunch Break & Poster Session Flame Foyer 14:00-14:30 Paola Picotti Institute of Biochemistry, ETH Zürich 14:30-15:00 Ubiquitin-Dependent Degradation: from Signaling to Disease Daniele Guardavaccaro Hubrecht Insitute Polar 15:00-15:30 Coffee Break Flame Foyer 15:30-16:00 Proteogenomics in analysis of mistranslation in bacteria Boris Macek University of Tübingen, Proteome Center Tübingen Polar 16:00-16:30 Myriam Ferro Polar 16:30 Drinks & Bites Flame Foyer Tuesday 27 January 09:30-10:00 Coffee & Tea Flame Foyer 10:00-10:30 Analysis of single cells through time and space my mass cytometry Polar 10:30-11:00 Transcription complex formation and its disruption in metastatic breast cancer Wilbert Zwart Netherlands Cancer Institute, Department of Molecular Pathology Polar 11:00-11:30 An enhanced strategy to identify disulfide-bridged and cross-linked peptides using EThcD Fan Liu Utrecht University, Biomolecular Mass Spectrometry and Proteomics Polar 11:30-12:00 Coffee Break Flame Foyer 12:00-12:30 Analysis of large proteomics datasets with MaxQuant in view of protein FDR Juergen Cox Max Planck Intitute of Biochemistry Polar 12:30-13:00 Drug profiling with Metabolomics Celia Berkers Utrecht University, Biomolecular Mass Spectrometry and Proteomics Polar 13:00-14:30 Lunch & Poser Session Flame Foyer 14:30-15:00 Brian Chait The Rockefeller University, Laboratory of Mass Spectrometry and Gaseous Ion Chemistry Polar 15:00-15:30 Proteomics of biological complex systems Eduard Sabido Aguade Centre for Genomic Regulation, Proteomics Unit Polar 15:30-16:00 Closure & Awards Polar 16:00-17:00 Drinks & Bites Flame Foyer Bernd Bodenmiller University of Zurich, Institute of Molecular Life Sciences