Resuscitation SAQ’s With regard to intravenous regional anaesthesia of the upper limb: List the indications List the contra-indications List the potential toxic effects of LA agents and how to minimise them in this context List the indications: • Closed forearm fractures needing reduction List the contra-indications: • Unco-operative patient • <10years old (persistent medullary circulation in humerus may allow access of LA into systemic circulation, unclear if this is of clinical significance, large series in children under ten show no significant complications) • compromised circulation to the limb • compartment syndrome in affected limb • presence of sickle cell disease or Raynaud's disease • fracture humerus on same side • soft tissue injury at tourniquet site • cellulitis/infected extremity • LA allergy • Cardiac conduction abnormalities • Hypertension, systolic >200mg Hg List the potential toxic effects of LA agents and how to minimise them in this context: • Premonitory CNS symptoms: (all potentiated by CO2 , pH) Perioral tingling Dizziness Tinnitus Unresponsiveness Agitation Nystagmus Muscle twitching • Seizures Usually self-limiting due to drug redistribution • CNS depression • Respiratory Hypoventilation, respiratory arrest • CVS Hypotension Arrhythmia (bradycardia, VF/VT) Myocardial depression Palpitations Vasodilation Bupivacaine most cardiotoxic • Allergy Allergy to amides are uncommon Prilocaine is only agent that should be used. Lignocaine and bupivacaine have high incidence of complications and death To minimize complications: Consent + warn patient of premonitory CNS symptoms Two doctors Appropriate area plus resuscitation equipment and drugs IV access in each arm – secured properly and not over joint Double cuff pneumatic tourniquet inflated to systolic BP plus 100mg Hg Check the radial pulse has disappeared before injecting prilocaine Cuff should be inflated for at least 20 minutes and no longer than one hour If toxicity does occur: Treat seizures with benzodiazepines Treat arrhythmias and arrest aggressively as acidosis, CO2, O2 cause worsening of toxicity A 2 year old child with severe dehydration arrives in the emergency department. He is floppy and unresponsive. Soon after arrival he suffers a PEA (Pulseless Electrical Activity) arrest. Question Describe your management Answer Answer and Interpretation FACEM SAQ Exam 2010.2 – Question 7 The overall pass rate for this question was 55/92 (59.8%) Pass Criteria Structured step-wise approach following paediatric ALS algorithm CPR continued throughout Emphasis on early circulatory access, IO if any delay in IV Appropriate weight related resuscitation doses of fluids and adrenaline Identify and treat reversible causes (4Hs and 4Ts) Good candidates also included: family support/discussion, cessation of resuscitation, post resuscitation care Features of unsuccessful answers Poor structure and flow – no smooth sequence of BLS to ALS Adrenaline – wrong dose, delays to administration or none given Failure to give adequate fluids, incorrect fluid volume Use of drugs to intubate (RSI) in cardiac arrest SAQ 080 A 17 year old girl with severe asthma has a respiratory arrest in your ED. Outline how you would go about intubating and ventilating her, and discuss the issues relating to IPPV in severe asthma. A 55 year old man has just undergone endotracheal intubation for severe asthma. Immediately post intubation, his systolic blood pressure falls to 80 mmHg. Question a. Outline the causes of post intubation hypotension in this man. b. Describe your ventilation strategy for this man. Answer Answer and Interpretation FACEM SAQ Exam 2006.2 – Question 5 The overall pass rate for this question was 54/57 (94.7%). Pass Criteria The examiners felt that this was a core emergency medicine question pitched at the right level for this examination. Overall most candidates performed well on this question. Part (a) required a discussion of possible causes which needed to include drugs, effects of PPV, barotrauma, hypoxia of various causes, cardiac events, dehydration and allergy. Part (b) required a structured approach to the problem addressing all the above mentioned conditions. In particular detail was required on the optimal ventilation settings for a patient with this presentation. Features of unsuccessful answers Candidates failed to pass this question if they missed a number of the key points above. ALTERNATIVE Describe the issues and process of intubation and ventilation in severe asthma ISSUES - Relative hypovolemia due to dehydration, decreased venous return - High airway pressures ++ - Long expiratory time - Auto/intrinsic PEEP – permissive hypercapnia - Risks of barotrauma, mucus plugging, alveolar collapse Intubation Fluid load Check K (may be low due to salbutamol) Aim for RSI with good pre-oxygenation (?biPAP, allow to sit up until last moment), cricoid pressure Prepare: Area – Full resus facilities with monitoring Equipment – Airway trolley including difficult airway, suction, early NGT (decompress inflated stomach, ileus due to low K), large ETT to allow bronchoscopy Drugs – consider ketamine 1mg/kg, otherwise fent and midaz, may need little if impending arrest, spray cords with lignocaine – avoid laryngospasm, suxamethonium 1.5mg/kg Staff – at least 2 airway-experienced doctors, designated nurses for airway, cricoid, documentation Ventilation Low RR ~ 6 High I:E ratio – allow long expiratory time Volume controlled ventilation 5-7ml/kg Pressure limited Low PEEP 2.5 – 5 if tolerated Optimise bronchodilation with beta-agonist, anticholinergic, MgSO4 via T-piece and po/iv steroid; treat underlying infection; treat pneumothorax with ICC Monitor for complications eg pneumothorax, mucus plugging SAQ 094 A 35 year old woman with known myasthenia gravis presents with a week of fever and productive cough. Her vital signs are: • Temp 38.5'C • P 130 • BP 100/80 • GCS 15 • SaO2 85 % on room air • FVC 750 mls a) Outline your management. (65%) b) Outline how you would go about inducing and maintaining general anaesthesia in this patient (35%) Issues Myasthenia gravis: - autoantibodies to post-synaptic Ach receptors at NMJ - sensitive to depolarizing paralytics - ocular mm. and respiratory mm. Risk of respiratory failure (definition: FVC < 15ml/kg = 900ml for 60kg patient) Probable community acquired pneumonia with hypoxia, hemodynamic compromise and serious comorbidity Management TREATMENT 1. Resus A monitor patency and protection (GCS) B RR, use of accessory muscles Hypoxia and low FVC – impending respiratory failure; will probably need emergent I&V; supplemental O2 15L via non-rebreather mask; biPAP (IPAP 12, EPAP 7, FiO2 to keep sats >93%) C IV access x 2 Fluid resus: early goal directed therapy in sepsis (Rivers et al, NEJM, 2001) Goals MAP 65 – 90 vasoactive agent CVP 8 – 12 IV fluid ScvO2 > 70% BTF to get Hct > 30% Dobutamine I&V to decrease O2 consumpn Shown to decrease in-hospital mortality Therefore: early aggressive fluid resuscitation within the first 6h D monitor GCS, pupils Monitor BSL 2. Specific treatment IV antibiotics: Community acquired pneumonia – Benzylpenicillin 2.4g load then 1.2g qid iv Erythromycin 500mg tds iv Also consider: ?aspiration/pseudomonas – ceftriaxone ?staph – flucloxacillin NB. Avoid aminoglycosides Tetracyclines Beta blockers Morphine Pethidine Antiarrhythmics IA, IB - cause prolonged NMJ block 3. Treatment of complications Coagulopathy, DIC – FFP, platelets, cryoppt Renal dysfunction – IV fluid, monitor UO, +/- hemodialysis Liver dysfunction Cerebral compromise SUPPORTIVE CARE Myasthenia – a. Cholinergic crisis therapy induced bronchorrhea generalized weakness withhold therapy b. Myasthenic crisis resp and pharyngeal paresis often early in Rx or post thymectomy Cholinesterase inhibitors: - neostigmine 2.5mg - pyridostigmine 60mg tabs 1-3tabs 2-4x/day both life-threatening - 4% mortality edrophonium test will distinguish - myasthenic crisis → improves - cholinergic crisis → worsens (resp deterioration, cardiac dysrhythmia) Prednisone 100mg/d Cytotoxics, plasmapheresis Chest physio Analgesics, antiemetics Nebulisers Bronchoscopy and toilet DISPOSAL ICU – monitor gas exchange, hemodynamics, renal function Input from intensivist, respiratory physician GENERAL ANAESTHETIC Issues Resistant to depolarizing agent – double dose Sensitive to non-depolarizing agent – don’t use Little resp reserve – desaturates quickly Elective intubation: Fasted – OT - anaesthetist Gas induction High dose suxamethonium ?awake fibreoptic intubation Emergent intubation: 1. RSI pre-oxygenate sedate with thiopentone or fent/midaz cricoid quick check that can ventilate with bag and mask high dose suxamethonium 200mg 2. Awake intubation pre-oxygenate – sedate – laryngoscopy – cophenylcaine spray to cords – ETT Maintenance of GA: Sedate with propofol or midaz only AVOID ongoing paralysis - spontaneous breathing with PEEP & PS SAQ 108 A term baby is delivered in an ambulance at the entrance to your ED. The child has no palpable cardiac output, no spontaneous respirations and is generally cyanosed at one minute of age. There is meconium in the baby's mouth. Outline your management. INTRO This is a time critical situation with immediate threat to life of newborn. Significant factors to consider 1-Baby- est weight 3.5KG -Asphyxia –Apgar between 1-3 at 1 minute nil CO or resp effort –CPR needed -meconium aspiration-associated complications aspiration,pneumothoraces, pulmonary hypertension 2-Mother-second patient issues- Medical- maternal conditions leading to asphyxia of infant ie, APH , Also likely needs to complete third stage -Psychological-unexpected life threat to her newborn infant- ideally separate staff member assigned to support. 3 -Father-psychosocial 4-Staff ,ambulance, nursing and medical need for de-brief post resuscitation I would call for help-paediatrics, midwife/obstetrics, and social worker. Two teams Team 1 baby Neonatal resuscitiaire overhead heater, timing device to start, full non invasive monitoring If the baby was still hypotonic with no respiratory effort I would Intubate 3.5 ETT baby and extubate suctioning simultaneously with meconium aspirator device. AIRWAY I would then immediately re-intubate and confirm ETT placement –Direct vision tube through cords, ETT CO2 (unreliable whilst no CO), bilateral air entry, ventilation aiming for chest wall rise and hopefully improvement in heart rate and colour. BREATHING If after 5 breaths with good chest rise there is no improvement of HR > 60BPM team member to commence chest compressions. CIRCULATION Chest compressions hand encircling technique thumbs in midline on sternum just below inter-nipple line aim for compression third depth of chest. 3 compressions to 1 ventilation once HR and palpable output > 60bpm and rising compressions can cease. If no response to above measure and lung inflation and adequate ventilation confirmed would administer 10mcg/kg of adrenaline 0.35mls 1 in 10,000 via IO/Umbilical venous catheter. Continue in cycles every 3-5minutes. History of volume loss re APH would give 10mls /kg of N.saline DISABILITY Dextrostix- BSL <2.5mmol/L slow bolus of 2-5mls/KG of 10% dextrose DRY baby use overhead heater maintain normothermia Throughout the resuscitation continual re-evaluation and team communication. DISPOSITION If good response to resuscitation will need admission to intensive care neonatal nursery. Potential need for inter-hospital transfer. Ideally allow mother to see, touch hold baby if condition allows. If no signs of cardiac output at 10 minutes outcome likely to be very poor, decision and discussion to stop effort should be made in conjunction with parents and paediatrician and team. If baby dies parents to have time to be with baby in private with staff member assigned for support. Need for debrief of all staff needed. TEAM 2 -mother Assessment ideally with midwife in team attention especially to psychological support. Completion of third stage of labour management of any complications. Disposition to post natal ward parents to be kept fully informed of babies condition. SAQ 331 A 42-year-old male is brought to your emergency department by ambulance after jumping off a nearby 3-storey building. His observations on arrival are: GCS 11/15 (E-3, M-5, V-3) HR 142 BP 78/40 RR 32 SaO2 94% (on 15 l/min O2 via non-rebreathing mask) T 36.9 (a) Outline your assessment of this patient. (50%) (b) Outline your management of this patient. (50%) 42 year old jumped from 3 stories • Hypotensive, tachycardic – likely hypovolaemic shock ?source of blood loss • GCS 11/15 ?major head injury • Tachypnoeic, Sats 94% on O2 • Probable suicide attempt Priorities 1) airway remains patent and protected and ventilation is adequate 2) Identify immediately treatable causes of hypotension/tachypnoea • Haemo/pneumothorax • Pelvic fractures esp. vertical shear with potential for major haemorrhage • Long bone fractures with potential haemorrhage 3) If no other cause identified and limited or no response to initial fluid resuscitation then should have exploratory laparotomy to exclude/treat intraabdominal source of bleeding. 4) Rapidly identify and treat neurosurgical cause of altered GCS 5) Identify / manage all other injuries along standard lines (many potential injuries) 6) Consider, identify and treat potential ingestions if confirmed suicide attempt Assessment and management occur concurrently and this should occur in a resuscitation area with a full trauma team response. (a) Assessment: History (collateral from witnesses / ambulance personnel): 1) This event • How landed • Injuries apparent, evidence of blood loss • Vital signs, conscious state and progression over time • Treatment so far eg. Fluids, analgesia, sedation and response to treatment • Evidence of drug ingestion eg. Note, pill packets, collateral 2) Past history (need to consult chart/family/sources collateral) • Past medical and surgical history • Past psychiatric history and social situation • Medications (?potential ingestions available) • Allergies Examination: Airway: • Assess for injury/patency and ability to protect, reevaluate continuously • C-spine examination not useful in view of conscious state Breathing: • Evidence of chest trauma, rib fractures (crepitus), pneumothorax (decr AE or expansion, s/c emphysema) , aspiration, contusion • Monitor resp rate/sats/oxygenation Circulation: • peripheral perfusion, PR, BP and response to treatment. • IDC & hourly urine measures • ?sources blood loss uising, urethral bleeding, abn prostate – bruising, tenderness, guarding, distension, PR • peripheral pulses • ? potential compartment syndrome areas Disability: • ?intracranial lesion needing OT: GCS, pupillary abnormality, hemiparesis, etc • head trauma, BOS#, facial fractures • ?spinal injury – complete neurological assessment including PR for documentation of spinal injury, level etc. • log roll and examination of entire spine Other specific examination: • Orthopaedic: above • Cardiothoracic: – bruits, pulse deficits or inequalities, BP differences – muffled heart signs, Kussmaul’s, distended neck veins • Soft tissue wounds or injury • Evidence of any toxidromes due to ingestion Investigations: Bedside: • BSL • ECG ?evidence of myocardial contusion etc • ABG to assess gas exchange, ventilation, acid-base status (?shock), initial Hb. Laboratory: • FBE – baseline Hb, platelets • UEG/LFT – baseline renal function and electrolytes, evidence of hepatic or tissue damage • Lipase - ? pancreatic injury X-match 4-6 units • Coag profile if requiring significant blood transfusion • Paracetamol/salicylate and other levels as indicated Radiology: • CXR & Pelvis – detection of injuries as above • C-spine/T-spine/L-spine indicated by mechanism and conscious state • X-rays any injured joint/bones in view mechanism • USS FAST of abdomen in conjunction surgeons – useful if hypotension/ongoing fluid requirements in the presence of other causes hypotension (major pelvic or long bone fractures or chest injury or spinal) to clarify need for immediate laparotomy • CT to detect injuries as above CTA chest viscous injury, pancreas) source of bleeding. • ?Pelvic angiography if haemodynamically unstable pelvic fractures Other • ?TOE in OT or ED to investigate aorta if instability or other injuries preclude CTA • DPL/DPA by surgical team as indicated (see below) (b) Management: Specific treatment: Airway: • GCS of 11/15 + RR32/sats 94% on 15 l/min + shock = elective intubation with RSI reasonable (not initially mandated). Ongoing assessment/monitoring essential if not intubated. • Entire spinal precautions with collar, log rolling etc Breathing: • Treat identified trauma along standard lines eg. ICC’s for haemo/pneumothorax • High flow oxygen (15 l/min) • Monitor adequacy ventilation/gas exchange with Sats and ABG Circulation: • Large bore peripheral access – 2 x 16g or larger • Initial fluid resuscitation of 2 litres N. Saline bolus. • Aim for MAP of 65-70 mm Hg or SBP> 100, PR < 100, UO >= 1ml/kg/hr, normal acid-base status. • no response to saline then packed cells, 2 units initially ?response. • Urgent surgical assessment required from outset and failure to respond to fluid resuscitation in absence of obvious cause (haemopneumothorax, peripheral fractures, pelvic fractures) indicates laparotomy. • Unstable pelvic fractures = pelvic binder or sheet tie • Major pelvic fractures + shock = DPL/DPA/or FAST to clarify need for laparotomy and use of ex-fix and/or angiography as per orthopods • External haemorrhage control. • Warm fluids to 37C Disability: • Neurosurgical lesion suspected = neurosurgical r/v, CT if able. Supportive management along standard lines for head injury. • Spinal cord injury = immobilisation, orthopaedic review re reduction of dislocations or decompressive surgery, methylprednisolone depending on local practices Other management of identified injuries or ingestions along standard lines Supportive care: • Analgesia – morphine in aliquots of 2.5 mg IV • Antiemetic as indicated • NGT as indicated • Maintain normothermia • Counsel relatives/friends Disposition: • OT as indicated • Likely to require HDU or ICU level monitoring in view of conscious state, hypotension, likely injuries. Certainly necessary if intubated. • Will need psychiatric input and assessment to clarify situation and ensure safety once recovering. 1. A 12 month old infant is brought to your ED after being found submerged and unresponsive in a local home swimming pool. CPR is in progress, and there has been no return of spontaneous circulation. 2. (a) Describe the technique you use to establish an intraosseous line. (70%) (b) What are the complications of an intraosseous line (30%) Describe the factors you use to decide the time to discontinue resuscitation of out of hospital cardiac arrest. 3. SAQ 1 2006/1 4. a. Outline the evidence for therapeutic hypothermia in post cardiac arrest patients. (30%) 5. b. Describe a protocol for therapeutic hypothermia in your ED. (70%) 6. SAQ 7 2006/1 7. A 55 year old man presents to triage complaining of throat tightness, itch, generalised erythema and 8. lip swelling whilst eating at a local Thai restaurant. 9. a. Outline your history and examination of this patient. (50%) 10. b. Describe your management of this patient. (50%) 11. 12. 13. SAQ 4 2007/1 14. Compare and contrast the cardiac arrest algorithm for asystole between adults and children older than one year. (100%) FACEM SAQ Exam 2007.1 – Question 4 The overall pass rate for this question was 22/55 (40.0%). Pass Criteria The examiners felt that this was an excellent core knowledge question on a topic recently overviewed in widely discussed concensus statements (ILCOR/AHA/ARC). It was thought to have been overall answered very poorly by most candidates. Good responses identified the differences in pathophysiology (and hence, priorities) in children, highlighted the potential reversible causes and exhibited knowledge of the recently published algorithms in this area. Features of unsuccessful answers Common errors in answering this question were incorrect drug doses, incorrect CPR ratios/rates, failure to mention intraosseous vascular access techniques and disregard of the differing pathophysiology. 15. SAQ 3 2007/2 16. A 72 year old man presents to the emergency department with a two day history of abdominal pain. A CT scan undertaken to investigate recent weight loss and jaundice shows a pancreatic mass lesion. 17. On examination, he is confused and jaundiced with maximal tenderness in the right upper quadrant. 18. His observations are: 19. Temp 39.8oC 20. 21. 22. 23. 24. PR 120 per min BP 100/65 mmHg RR 22 per min O2 Sat 98% on oxygen 6 LPM Describe your management. (100%) 25. 26. SAQ 5 2007/2 27. Discuss the pharmacological options available (including dosages and modes of delivery) to treat anaphylaxis in the emergency department. (100%) 28. 29. SAQ 6 2007/2 30. A 58 year old patient who is undergoing Continuous Ambulatory Peritoneal Dialysis for end stage renal disease presents with a 6 hour history of severe abdominal pain and vomiting. 31. His observations are: 32. Temp 38.8oC 33. PR 110 per min 34. BP 150/90 mmHg 35. RR 22 per min 36. O2 Sat 98% on oxygen 6 LPM 37. Describe your assessment. (100%) Discuss the strategies available in the event of a failed orotracheal intubation. ~ You are preparing to semi-urgently intubate a patient a.) outline how you assess the likelihood of this being a difficult intubation b.) describe your approach to managing a potentially difficult intubation. 7. An 86 year-old woman is brought in by ambulance from her nursing home. She was found unconscious in her room, 12 hours after being seen to be her usual self. Preliminary findings: GCS 3 (tolerating oro-pharyngeal airway) BP 200/110 mmHg HR 50 bpm Temp 31 deg C Outline your approach to this case (100%). Issues Immediate control of critically unwell patient – assume team leadership, and establish order and direction early Preliminary assessment: o Immediate life threats o Cause of coma – stroke, incl ICH o Complications of coma – hypothermia, hypoglycaemia, other Preliminary management o Airway support o Rewarming o Metabolic correction (eg hypoglycaemia) Ongoing: o CT Brain – with our without ETT o End of Life Consideration - depends on more info from NOK, NH, GP etc o Palliative care is paramount. Additional Rx beyond this is subject to multiple factors, including time. o Appropriate disposition Liaison with family / NOK is crucial SAQ 2 Discuss the use of non-invasive ventilation in the emergency department. (100%) The overall pass rate for this question was 39/67 (58.2%). Pass criteria Primary rationale for CPAP is correction of hypoxaemia versus correction of hypercarbia for BiPAP Understanding of the physiologic advantages of these therapies – both decrease work of breathing and improve V/Q matching Specific concerns re risk of aspiration Specific concerns re patient tolerability / acceptability Technical / nursing load and demands created by both therapies SAQ 4 Compare and contrast the cardiac arrest algorithm for asystole between adults and children older than one year. (100%) The overall pass rate for this question was 22/55 (40.0%). The examiners felt that this was an excellent core knowledge question on a topic recently overviewed in widely discussed concensus statements (ILCOR/AHA/ARC). It was thought to have been overall answered very poorly by most candidates. Good responses identified the differences in pathophysiology (and hence, priorities) in children, highlighted the potential reversible causes and exhibited knowledge of the recently published algorithms in this area. Common errors in answering this question were incorrect drug doses, incorrect CPR ratios/rates, failure to mention intraosseous vascular access techniques and disregard of the differing pathophysiology. SAQ 6 A 62 year old man with known chronic renal failure presents with respiratory failure, secondary to pulmonary oedema. Oxygen saturation is 89% on 100% oxygen utilizing bi-level positive airway pressure (BiPAP). His observations are: Glasgow Coma Score 14 Temperature 37.0oC Respiratory Rate 32 /min Systolic blood pressure 90 mmHg Electrocardiograph Rate of 105 /min with a regular broad complex rhythm. An urgent Potassium level of 8.7 mmol/L (Reference Range: 3.5-4.9 mmol/L) has been recorded. Discuss rapid sequence induction in this man. (100%) The overall pass rate for this question was 23/56 (41.1%). Examiners noted that this was a challenging question that required far more than a simple description of an RSI template. In particular as a discuss question it required consideration of whether RSI was appropriate at all, alternative approaches, the clinical context of a patient with life threatening hyperkalaemia and the pros and cons of elements of RSI such as drugs, posture, haemodynamics etc. SAQ 2 Discuss the role of adrenaline and vasopressin in cardiac arrest. The overall pass rate for this question was 33 / 64 (51.6%). It was expected that a good answer would explain the current place of both drugs in resuscitation guidelines but with an appreciation of the limited evidence for the efficacy of either. As a discuss question a solid list of pros and cons was expected with this being a good opportunity to discuss some of the quality of evidence issues. Failing answers lacked pros and cons, had limited detail and made incorrect assertions regarding the role of the drugs. 2008.2 SAQ 4 Compare and contrast propofol and ketamine for procedural sedation in the emergency department. (100%) SAQ 4 Describe a detailed protocol for the use of propofol in the emergency department. The overall pass rate for this question was 22 / 44 (50%). The expectation was that candidates would provide substantial detail in this answer on a topic in which they could reasonably be expected to have a high level of knowledge. Although technical issues such as pharmacology, dosing, indications were clearly required this in itself was not sufficient to pass. Since the question asked for a detailed protocol examiners expected that more managerial issues such as consent, credentialing of staff and audit would be addressed. 2. What features would you want in a patient trolley (bed) for a resuscitation area? Justify your answer.