Central Michigan University
College of Arts & Sciences
Course Syllabus
CHM 211
Desg. No.
I.
Quantitative Analysis
Title
4(3-5)
Credit(Mode)
Bulletin Description
Gravimetric, volumetric, spectroscopic, and electroanalytical methods of analysis.
II.
Prerequisites
CHM 132 or 161, or advanced placement
III.
Rationale for Course Level
No change
IV.
Textbooks and Other Materials to be Furnished by the Student
Textbook on elementary quantitative analysis (instructor's choice), laboratory notebook,
and safety goggles.
V.
Special Requirements of the Course
None
VI.
General Methodology Used in Conducting the Course
Formal lectures (three hours per week) with extra time set aside for problem solving &
discussion. Laboratory: Laboratory work for (a minimum of) five hours per week with
extra time set aside for lab/lecture discussions and additional experimental work.
Quantitative analysis on several unknown samples are preformed.
VII.
Course Objectives
VII.
Course Outline
Representative Textbook:
D.C. Harris, Quantitative Chemical Analysis, 3rd Ed., W.H.
Freeman & Co., 1991.
Required Course Materials: Laboratory notebook, Safety Goggles.
Course Evaluation:
Examination and Homework
Laboratory Results
70%
30%
Course Description:
The following topics should be covered in any course in
elementary quantitative analysis. These are primarily lecture
topics, but will also supplement the understanding on laboratory
exercises and experiments in this course.
I.
Introduction - What are Quantitative Analysis and
Analytical Chemistry?
II.
Fundamental Concepts (1 week)
A)
Units and Concentrations
B)
Tools of the Trade
III.
Data Treatment (1 week)
A)
Accuracy and precision
B)
Significant figures
C)
Determination & indeterminant errors
D)
Confidence limits
IV.
Gravimetric Methods (1 week)
A)
Precipitation phenomena
B)
Gravimetric factor
C)
Gravimetric method
V.
Solubility Factors (1 week)
A)
Ionic strength
B)
Activity coefficients
C)
Equilibrium constants
VI.
Volumetric Methods (6 weeks)
A)
Acid - Base equilibria
B)
Precipitation methods
C)
Complex formation
D)
Redox titrations
VII.
Spectrophotometry (2 weeks)
A)
Electromagnetic spectrum
B)
Interacttion of energy with molecules
C)
Beer's Law
D)
Ultraviolet - Visible (Molecular)
E)
Ultraviolet - Visible (Atomic)
F)
Instrumentation
G)
Applications
H)
Errors
IV.
Final Exam
Representative Laboratory Schedule:
1st Week:
Check into Lab. Introduction of Analytical Mettler balance and
volumetric glassware. Calibration of a 10 ml transfer pipet and 50 ml
buret.
2nd Week:
Volumetric standardization of sodium hydroxide ((NaOH) with primary
standard potassium acid phthalate (KPH). Analysis of unknown KHP and
NaOH. Potentiometric titration of unknown KHP and NaOH.
3rd Week:
Volumetric standardization of hydrochloric acid (HCl) with primary
standard sodium carbonate (NA2CO3). Analysis of unknown Na2CO3 with
HCl. Potentiometric titration of unknown Na2CO3 with HCl.
4th Week:
Volumetric standardization of silver nitrate (AgNO3) with standard
sodium chloride (NaCl). Volumetric determination of unknown chloride
using AgNO3. Potentiometric titration of unknown chloride AgNO3.
5th Week:
Potentiometric standardization of ceric bisulfate [Ce(HSO4)4] with
primary standard ferrous ammonium sulfate [Fe(NH4)2(SO4)2].
Potentiometric determination of unknown iron in an ore with [Ce(HSO4)4].
6th - 8th Week:
Spectrophotometric (UV-VIS molecular) standardization using five
primary standard ferrous ammonium sulfate [Fe(NH4)2(SO4)2] and 1,10phenanthroline calibration solutions. Spectrophotometric determination of
unknown trace iron using Beer's Law calibration plot from above
standardization.
9th - 10th Week:
Voltammetry experiment
11th - 12th Week:
Coulometry experiment
13th - 15th Week:
Atomic Absorption or Emission experiment
Supplementary References:
1.
2.
3.
4.
W.J. Blaedal and V.W. Meloche, Elementary Quantitative Analysis, 2nd Ed., Harper and
Row, 1963.
G.H. Ayres, Quantitative Chemical Analysis, 2nd Ed., Harper and Row, 1968.
L.F. Hamilton and S.G. Simpson, Calculations of Analytical Chemistry, 7th Ed.,
McGraw-Hill, 1985.
D.A. Skoog, D.M. West, F.J. Holler, Fundamentals of Analytical Chemistry, Saunders,
1992.
IX
Evaluation
Thirty percent of the grade is determined by the student's accuracy and precision in his
analysis of several unknowns. Seventy percent of the grade is determined by the
student's performance on several hour exams and a final examination.
X.
Bibliography
1.
W.J. Blaedal and V.W. Meloche, Elementary Quantitative Analysis, 2nd Ed.,
Harper and Row, 1963.
2.
3.
G.H. Ayres, Quantitative Chemical Analysis, 2nd Ed., Harper and Row, 1968.
L.F. Hamilton and S.G. Simpson, Calculations of Analytical Chemistry, 7th Ed.,
McGraw-Hill, 1985.
D.A. Skoog, D.M. West, F.J. Holler, Fundamentals of Analytical Chemistry,
Saunders, 1992.
4.
Syllabus prepared by:
John P. Warriner
Name
4/2/92
Date