THEMATIC PLAN OF LECTURES ON TOXICOLOGICAL CHEMISTRY for 5 teaching year students of foreign faculty speciality 8.110201 "Pharmacy" 2014/2015 ed. Year № 1. 2. 3. 4. 5. 6. 7. 8. Topic 1 Module Introduction into Toxicological Chemistry. Amount of hours Date 1 22.01.2015 23.01.2015 29.01.2015 30.01.2015 5.02.2015 6.02.2015 12.02.2015 13.02.2015 19.02.2015 20.02.2015 26.02.2015 27.02.2015 5.03.2015 6.03.2015 12.03.2015 13.03.2015 Group of substances isolated from the biological material by mineralization. Methods of mineralization. Analysis of the mineralizate by the chemical method. 1 Group of substances isolated by steam distillation. Methods of volatile poison isolation. Chemical method of the volatile poison analysis. 1 Analysis of volatile poisons in the biological fluids by GLC. Pesticides. Classification, toxicological value, chemical-toxicological analysis. The basic regularities of the toxic substance behaviour in the body. Methods of natural and artificial decontamination at acute poisonings. 1 Head of the department, prof. 1 1 1 1 I.A. Zhuravel THEMATIC PLAN OF LABORATORY CLASSES ON TOXICOLOGICAL CHEMISTRY for 5 teaching year students of foreign faculty speciality 8.110201 "Pharmacy" 2014/2015 ed. year № Topic Amount Date of hours Rating 4 19.01 – 23.01 26.01 – 30.01 3–4 2.02– 6.02 3–5 + 1 Module 1. 2. 3. 4. 5. 6. 7. 8. Introduction into Toxicological Chemistry. Making the plan of forensic toxicological examination. External examination of the sample and some preliminary tests. The group of substances isolated from the biological material by mineralization. Methods of the biological material mineralization. Examination of the mineralizate by the chemical method. Destruction of the biological material and examination of the destructate for mercury (II) cation. Quantitative determination of lead compounds in the mineralizate by photocolorimetric method. The Test. The group of subtances isolated from the biological material by steam distillation (volatile poisons). The methods of volatile poison isolation from the biological material. Identification of volatile poisons by chemical method. Examination of the distillates for cyanide, formaldehyde and halocarbons Identification of volatile poisons by chemical method. Examination of the distillate 2 for monobasic alcohols, acetone, phenol and acetic acid. Analysis of the distillates and biological fluids (blood and urine) for volatile poisons by gas-liquid chromatography (GLC) method. The group of substances isolated from the biological material by organic solvent extraction (pesticides). Chemical toxicological analysis of organophosphorus pesticides. The Test. Final control class of the 1 module mastering 4 4 4 9.02– 13.02 4 16.02 – 20.02 23.02 – 27.02 2.03– 6.03 4 4 4 32 All Head of the department, prof. 9.03– 13.03 2–4 10–16 2–4 2–4 2–4 2–4 + 10–16 25–40 61–100 I.A. Zhuravel