Chlorine: Guidance for Health Care Providers

Virginia Department of Health
Chlorine: Overview for Healthcare Providers
Potential Sources
Route of Exposure
Risk Indicators
Cause of Death
Laboratory tests/
Sample collection
CAS number: 7782-50-5
UN number: 1017
Yellowish green gas with bleach-like, sharp, burning odor
Odor detection: 0.2 – 3.5 ppm; mild symptoms: 1-3 ppm; lowest reported lethal level: >430 ppm
Immediately Dangerous to Life or Health (IDLH): 10 ppm
Chlorine is one of the most common industrial chemicals used in manufacturing and is transported
in large tanker cars by rail and highway. It is often shipped as a liquid but readily becomes a gas
when released from its container. Commonly used for disinfecting water. Chlorine comes in
other forms such as sodium hypochlorite (bleach).
Most common route of exposure is by inhalation. Injury can also occur from skin contact.
Contamination: Patients with gas exposure are unlikely to have secondary contamination and pose
little risk of causing harm to healthcare providers. Liquid products, such as industrial-strength
chlorine bleach, can off-gas from contaminated clothing, hair and skin. Patients contaminated
with liquid product pose a risk of releasing chlorine gas into the breathing space of healthcare
providers. Decontamination: Decontaminate outside of hospital. Clothing removal and copious
water rinse are adequate to decontaminate an exposure to liquid product. After decontamination,
standard precautions are adequate for handling patients. NOTE: a chlorine (bleach) odor may
persist on the patient’s skin despite adequate decontamination.
Extent of injury depends on the concentration and duration of exposure. Chlorine exposure may
exacerbate underlying chronic diseases. Those with reactive airways disease, chronic pulmonary
diseases, or cardiovascular disease are more susceptible to smaller exposures and may have
serious effects.
Deaths are due to respiratory compromise or cardiovascular effects from respiratory compromise.
Extremely high concentrations (especially in enclosed space) can result in asphyxiation.
Most exposures result in immediate irritant symptoms. Mild symptoms typically resolve within a
few hours. Delayed pulmonary edema has developed hours after exposure in patients with
persistent or severe symptoms at the time of exposure.
 ENT: Burning eyes, nose and throat
 Respiratory: Cough, chest pain (burning sensation), shortness of breath, wheezing,
hypoxemia, tachypnea, hemoptysis, delayed pulmonary edema
SKIN: Gas exposure can cause irritation of skin. Direct skin contact with high concentrations or
prolonged duration causes corrosive burns. Serious skin injuries are likely to have associated
inhalational injury.
Confirmatory diagnostic testing: None. On-scene environmental monitoring may provide the best
evidence of the presence of chlorine.
Monitor clinical effects and complications: CXR, ABG, oxygen saturation, peak flow as indicated.
CXR findings are not specific for chlorine but may confirm the presence of acute lung injury.
Supportive Care: Fresh air, humidified oxygen, and bronchodilators. Aerosolized sodium
bicarbonate has sometimes been used as a therapy but with unproven benefit.
Antidotes: None
Pitfall: Not recognizing patients at risk for progressive lung injury. Those with significant
signs of toxicity shortly after exposure may improve but exhibit persistent symptoms and several
hours later have a worsening condition with noncardiogenic pulmonary edema.
Disposition: Asymptomatic patients and those who experienced only minor symptoms that resolve
within 1-2 hours may be released.
All chemical exposures should be reported to the regional poison center at 1-800-222-1222.
Outbreaks and unusual occurrences are reportable to your local health department. If this is a
suspected emergency then report the incident to the local 911 center.
For more information, refer to: Virginia Department of Health, and the Centers for Disease Control and
Prevention, or
Updated 07/19/2004