2nd Conference on Cardiac Arrest and Sudden Death – Cardiovascular Therapy June 16-18, 2011, Panum Institute, Blegdamsvej 3B, 2200 Copenhagen N, Denmark Conference of European Society of Cardiology (ESC) Working Group on Cardiovascular Pharmacology and Drug Therapy Scientific program (Note: This is a preliminary program. Not all speakers/chairmen have yet confirmed participation) Thursday 16. June 2011 Opening of Conference Haderup Auditorium 13.30-13.40 Welcome to Copenhagen. President of conference Stig Haunsø, Copenhagen, Denmark. 13.40-13.50 Welcome to the Conference. Chairman of ESC Working Group on Cardiovascular Pharmacology and Drug Therapy Luis Ruilope, Madrid, Spain. 13.50-14.0 Welcome to the Science. Chairman of conference, Vice-chairman of ESC Working Group on Cardiovascular Pharmacology and Drug Therapy Keld Kjeldsen, Copenhagen, Denmark. Symposium 1: Influencing sudden cardiac death by pharmacotherapy - A symposium arranged by European Society of Cardiology Working Group on Cardiovascular Pharmacology and Drug Therapy Haderup Auditorium Chairmen: Bertram Pitt, Ann Arbor, USA and Keld Kjeldsen, Copenhagen, Denmark. 14.00-14.20 Polypharmacy in patients with heart disease – risk of sudden cardiac death Faiez Zannad, Nancy, France 14.20-14.40 How to ensure safe polypharmacy? Joseph Brugada, Barcelona, Spain 14.40-15.00 Anti-aldosterone therapy also to mild heart failure and severe hypertension Luis Ruilope, Madrid, Spain 15.00-15.20 A new era for digoxin Mihai Gheorghiade, Chicago, USA 15.20-15.40 Algorithm to protect patients on psychoactive drugs against sudden cardiac death. Steen Pehrson, Copenhagen, Denmark 1 Symposium 2: The sudden cardiac death burden - epidemiology Hannover Auditorium Chairmen: Christine Albert, Boston, USA and Mads Melby, Copenhagen, Denmark 14.00-14.20 Sudden cardiac death in women Christine Albert, Boston, USA 14.20-14.40 Sudden cardiac death in the young Bo Winkel, Copenhagen, Denmark 14.40-15.0 Sudden death in the general population Sumeet Chugh, Oregon, USA 15.00-15.20 Sudden death in athletes Hanne Rasmusen, Copenhagen, Denmark 15.20-15.40 Register study of sudden cardiac death Mads Melby, Copenhagen, Denmark Free oral presentations based on accepted abstracts session 1 Mødesal Chairmen: Morten Olesen, Copenhagen, Denmark and … 14.00-14.15 14.15-14.30 14.30-14.45 14.45-15.00 15.00-15.15 15.15-15.30 15.30-15.45 Posters (15.45-16.30) Exhibitions (15.45-16.30) Coffee (15.45-16.30) Symposium 3: Danish research in the pipeline in patients at risk of cardiac arrest and sudden death - A symposium co-arranged by Danish Society of Cardiology Haderup Auditorium 2 Chairmen: Christian Hassager and Stig Haunsø, Copenhagen, Denmark 16.30-16.50 Sudden cardiac death risk from drugs in general use Gunnar Gislason, Gentofte, Denmark 16.50-17.10 The DANISH trial - Danish ICD study in non-ischemic heart failure Lars Køber, Copenhagen, Denmark 17.10-17.30 DANPACE - Is dual-chamber pacing superior? Jens Cosedis Nielsen, Århus, Denmark 17.30-17.50 Atrial fibrillation as predictor for sudden cardiac death in patients with aortic stenosis Kristian Wachtell, Gentofte, Denmark 17.50-18.10 Therapeutic hypothermia after cardiac arrest Christian Hassager, Copenhagen, Denmark Symposium 4: Heritability in sudden cardiac death Hannover Auditorium Chairmen: Carlo Napolitano, Pavia, Italy and Jacob Tfelt-Hansen, Copenhagen, Denmark 16.30-16.50 Underlying genetic causes of sudden cardiac death Jacob Tfelt-Hansen, Copenhagen, Denmark 16.50-17.10 Genetic modifiers of LQT/Brugada syndromes Carlo Napolitano, Pavia, Italy 17.10-17.30 The J-wave syndrome – a unifying diagnosis? Michel Haïsseguerre, Bordeaux-Pessac, France 17.30-17.50 Genome wide association studies Arthur Wilde, Amsterdam, Netherlands 17.50-18.10 Genetically based treatment of catecholaminergic polymorphic ventricular tachycardia Bjorn Knollmann, Nashville, USA Workshop 1: What is optimum plasma-potassium? - A workshop arranged by European Society of Cardiology Working Group on Cardiovascular Pharmacology and Drug Therapy Mødesal Chairmen: Luis Ruilope, Madrid, Spain and Dan Atar, Oslo, Norway Panellists: Stefan Agewall, Oslo, Norway, Angeles Alonso, Madrid, Spain, Mihai Gheorghiade, Chicago, USA, Keld Kjeldsen, Copenhagen, Denmark, Kurt Stochitzky, Gras, Austria, Faiez Zannad, Nancy, France 16.30-16.50 What to learn on potassium from recent trials? 3 16.50-17.10 17.10-17.30 17.30-17.50 17.50-18.00 18.00- Bertram Pitt, Ann Arbor, USA Update on potassium pharmacology and physiology Torben Clausen, Århus, Denmark Mechanisms for potassium associated arrhythmia Oleg Osadchii, Copenhagen, Denmark News from potassium-pump studies on atrial fibrillation, hypo- and hyperkalemia Cao Tran, New York, USA Discussion and conclusion by panellists, speakers and chairmen Meeting of the Nucleus of ESC Working Group on Cardiovascular Pharmacology (Only for nucleus members) Mødesal 20.00- Tivoli Gardens. Conference dinner at Restaurant Hercegovina (entrance from Tivoli Gardens) Friday 17. June 2011 Symposium 5: Non-pharmacological prevention of sudden cardiac death - A symposium co-arranged by European Heart Rhythm Association. Haderup Auditorium Chairmen: Angelo Auricchio, Lugano, Switzerland and Jesper Hastrup Svendsen, Copenhagen, Denmark. 08.30-08.50 Should all patients with low EF have an ICD? Massimo Santini, Rome, Italy 08.50-09.10 Cardiac resynchronization therapy: Past, present and future Angelo Auricchio, Lugano, Switzerland 09.10-09.30 Catheter ablation to prevent ventricular arrhythmia Michel Haïssaguerre, Bordeaux, France 09.30-09.50 Remote monitoring of ICD-patients: Will early arrhythmia detection reduce the risk of sudden ventricular arrhythmia? Helen Høgh Petersen, Copenhagen, Denmark 09.50-10.10 Atrial fibrillation as a risk factor of sudden arrhythmic death Andreas Goette, Paderborn, Germany Symposium 6: Recommendations for everyday living after cardiac arrest 4 - Allied personal symposium Hannover Auditorium Chairmen: Thor Edvardsen, Oslo, Norway and Selina Kikkenborg Berg, Copenhagen, Denmark 08.30-08.50 Driving recommendations after cardiac arrest Tone Norekval, Bergen, Norway 08.50-09.10 Physical activity – what to recommend? Luc Vanhees, Leuven, Belgium 09.10-09.30 Physiological reactions – recommendations for professional follow-up Samuel Sears, Greenville, USA 09.30-09.50 Recommendations for relatives Ann-Birgitte Vogelsang, Århus, Denmark 09.50-10.10 Recommendations for gender specific care Susanne Pedersen, Rotterdam, Netherlands Workshop 2: How to reduce the risks in polypharmacy? - A workshop arranged by European Society of Cardiology Working Group on Cardiovascular Pharmacology and Drug Therapy Mødesal Chairmen: Faiez Zannad, Nancy, France and Luis Ruilope, Madrid, Spain Panellists: Stefan Agewall, Oslo, Norway, Dan Atar, Oslo, Norway, Keld Kjeldsen, Copenhagen, Denmark, Basil Lewis, Haifa, Israel, Giuseppe Rosano, Sulmona, Italy, Atul Pathak, Toulouse, France, Harald Schmidt, Bonn, Germany, Kurt Stoschitzky, Graz, Austria, Sven Wasmann, Bonn/Montreal, Germany/Canada 08.30-08.50 Are clinical trails reflecting “real life” patients? Mihai Gheorghiade, Chicago, USA 08.50-09.10 May the personalized polypill improve compliance? Angeles Alonso, Madrid, Spain 09.10-09.30 Will new anticoagulants and antiplatelets reduce bleeding – Role of genetics? Steen Husted, Århus, Denmark 09.30-09.50 Can computer programmes ensure rational polypharmacy? Emilia Villa, Madrid, Spain 09.50-10.10 Discussion and conclusion by panellists, speakers and chairmen Free oral presentations based on accepted abstracts session 2 Sofastue Chairmen: Anders Holst, Copenhagen, Denmark and… 5 08.30-08.45 08.45-09.00 09.00-09.15 09.15-09.30 09.30-09.45 09.45-10.00 10.00-10.15 10.15-14.30 Meeting of the nucleus of ESC Working Group on Cardiovascular Pharmacology (Only for nucleus members) Mødesal Posters (10.10-11.00) Exhibitions (10.10-11.00) Coffee (10.10-11.00) Symposium 7: Treatment of out-of-hospital cardiac arrest Haderup Auditorium Chairmen: Pyotr Platonov, Lund, Sweden and Steen Pehrson, Copenhagen, Denmark 11.00-11.20 Automated external defibrillators – where should they be located? Fredrik Folke, Gentofte, Denmark 11.20-11.40 New ESC guidelines for treatment of cardiac arrest Morten Rosenqvist, Stockholm, Sweden 11.40-12.0 0 Improving prehospital treatment of cardiac arrest Freddy Lippert, Copenhagen, Denmark 12.00-12.20 Work-up of patients surviving cardiac arrest. Henning Bundgaard, Copenhagen, Denmark Symposium 8: ECG parametres in drug evaluation Hannover Auditorium Chairmen: Jean-Philip Couderc, Rochester, USA and Egon Toft, Aalborg, Denmark 11.00-11.20 Tales from the T-wave: What have we learned form the congenital LQT-syndrome? Jørgen Kanters, Copenhagen, Denmark 11.20-11.40 Dynamic evaluation of repolarization variability in drug studies Nils Edvardsson, Mölndal, Sweden 6 11.40-12.00 T-wave morphology as a covariate to QTc in drug safety evaluation Claus Graff, Aalborg, Denmark 12.00-12.20 Results from the Telemetric and Holter ECG Warehouse Jean-Philip Couderc, Rochester, USA Young investigators award session based on accepted abstracts - A session co-arranged by European Society of Cardiology Council on Basic Cardiovascular Science Sofastue Chairmen: Axel Pries, Berlin, Germany, Karin Sipido, Leuven, Belgium, Carlo Napolitano, Pavia, Italy, Michael McKenna, Melbourne, Australia, and Niels-Henrik Holstein-Rathlou, Copenhagen, Denmark 11.00-11.20 11.20-11.40 11.40-12.00 12.00-12.20 Exhibitions (12.20-14.30) Lunch (12.20-14.00) Moderated posters (13.30-14.30) Chairmen: Bo Winkel, Copenhagen, Denmark and... Abstracts will be published in Fundamental & Clinical Pharmacology. Symposium 9: Handling of relatives to young sudden cardiac death victims -A symposium co-arranged by Centre for Inherited Cardiac Diseases, Rigshospitalet, Copenhagen, Denmark Haderup Auditorium Chairmen: Arthur Wilde, Amsterdam, Netherlands and Henning Bundgaard, Copenhagen, Denmark 14.30-14.50 Autopsy in young sudden cardiac death victims: An algorithm for the pathologist Mary Sheppard, London, UK 14.50-15.10 Cardiomyopathies and sudden cardiac death in the young Carolyn Ho, Boston, USA 15.10-15.30 Molecular autopsy in sudden cardiac death victims 7 Laurence Nunn, London, UK 15.30-15.50 Outcome and psychological impact of screening of child relatives Morten Jensen, Copenhagen, Denmark 15.50-16.10 Work-up of relatives to young sudden cardiac death victims Arthur Wilde, Amsterdam, Netherlands Symposium 10: News on mechanisms in cardiac arrest - A symposium co-arranged by ESC Council on Basic Cardiovascular Sciences Hannover Auditorium Chairmen: Axel Pries, Berlin, Germany and Søren-Peter Olesen, Copenhagen, Denmark 14.30-14.50 Update on molecular mechanisms Karen Sipido, Leuven, Belgium 14.50-15.10 Modelling LQT syndrome Morten Grunnet, Copenhagen, Denmark 17.30-17.50 New methods for predicting mutation pathogenicity Lior Gestein, Haifa, Israel 15.30-15.50 Patch-clamp in cardiomyocytes Karl-Ludwig Laugwiz, Munich, Germany 15.50-16.10 Whole Exon sequencing Yalda Jamshidi, London, UK Free oral presentations based on accepted abstracts session 3 Mødesal Chairmen: Cao Tran, New York, USA and … 14.30-14.45 14.45-15.00 15.00-15.15 15.15-15.30 15.30-15.45 15.45-16.00 16.00-16.15 Free oral presentations based on accepted abstracts session 4 Sofastue Chairmen: Bo Winkel, Copenhagen, Denmark 14.30-14.45 8 14.45-15.00 15.00-15.15 15.15-15.30 15.30-15.45 15.45-16.00 16.00-16.15 Exhibitions (16.10-16.30) Coffee (16.10-16.30) Workshop 3: How to avoid sudden cardiac death in sports? Mødesal Chairmen: Michael McKenna, Melbourne, Australia and Michael Kjær, Copenhagen, Denmark Panellists: Stefan Agewal, Oslo, Norway, Henning Bundgaard, Copenhagen, Denmark, Andreas Goette, Paderborn, Germany, Samuel Sears, Greenville, USA, Luc Vanhees, Leuven, Belgium, 16.30-16.50 Epidemiology Eva Prescott, Copenhagen, Denmark 16.50-17.10 ECG in athletes Mats Borjesson, Corrado, Italy 17.10-17.30 Potassium during exercise Michael McKenna, Melburne, Australia 17.30-17.50 Should all elite athletes be screened for heart disease? Jan Kyst Madsen, Gentofte, Copenhagen 17.50-18.00 Discussion and conclusion by panellists, speakers and chairmen Free oral presentations based on accepted abstracts session 5 Sofastuen Chairmen: Morten Jensen, Copenhagen, Denmark and… 16.30-16.45 16.45-17.00 17.00-17.15 17.15-17.30 17.30-17.45 17.45-18.00 9 Evening free Saturday 18. June, 2011 Ad hoc workshop 4 Mødesal Chairmen: To be determined 09.30-09.50 09.50-10.10 10.10-10.30 Break 10.50-11.10 11.10-11.30 11.30-11.50 Free oral presentations based on accepted abstracts session 6 Sofastue Chairmen: To be determined 09.30-09.45 09.45-10.00 10.00-10.15 10.15-10.30 Break 11.00-11.15 11.15-11.30 11.30-11.45 11.45-12.00 Conference is closed 10