Unit overview
Human Biological Science Unit 3A
Gene expression
Variation and gene pools
Speciation and evidence
for evolution
Gene expression
Variation and gene pools
Speciation and evidence
for evolution
Disruption to
homeostasis
Homeostasis
Communication – The
endocrine system
Communication – The
nervous system
Content cells
Human form and function
Human diversity and change
The practice of human biology
1.
Disruption to
homeostasis
Homeostasis
Communication – The
endocrine system
Unit content
Communication – The
nervous system
Content cells
Human form and function
Cells, metabolism and
regulation
Cellular activities:
1.1
1.2
role of cell membrane
structure and function in
active transport and as a
receptor
DNA controls the production of
cellular materials
Homeostasis by feedback systems:
1.3
components of a
stimulus–response feedback
model
1.4
homeostatic mechanisms
that control:

body temperature

body fluid composition

blood sugar

gas concentrations

blood pressure
© WestOne Services 2009
SCIENCE1218
1
Content cells
1.5
Speciation and evidence
for evolution
Variation and gene pools
Module 2 Variation – the
spice of life!
Gene expression
Disruption to
homeostasis
Homeostasis
Communication – The
endocrine system
Unit content
Communication – The
nervous system
Module 1 Maintaining the
balance
physiological and
behavioural mechanisms
that influence maintenance
of homeostasis of the above
conditions.
Disruption of homeostasis:
1.6
causes of disruption
1.7
hormonal
eg insulin–diabetes
1.8
behavioural eg drugs,
excessive activity, eating
habits
1.9
disease eg emphysema
1.10
treatments for disruption of
homeostasis.
Body systems
Endocrine systems:
1.11
types and location of
endocrine glands
1.12
relationship between the
hypothalamus and pituitary
1.13
production site, target organ
and effect of various
hormones
1.14
feedback loops involving
endocrine activity
1.15
hormonal modes of actions.
Autonomic nervous system:
1.16
overview of divisions of the
nervous system
© WestOne Services 2009
SCIENCE1218
2
Content cells
1.17
relationship of the autonomic
NS to the body’s nervous
system
1.18
divisions of the autonomic
NS and their effect on
various body organs
1.19
comparison of hormones and
nerves in terms of speed,
duration, transmission and
specificity.
2.
Human diversity and change
Speciation and evidence
for evolution
Variation and gene pools
Module 2 Variation – the
spice of life!
Gene expression
Disruption to
homeostasis
Homeostasis
Communication – The
endocrine system
Unit content
Communication – The
nervous system
Module 1 Maintaining the
balance
Inheritance
Gene expression:
2.1
effect of the environment on
gene expression
eg effect of UV light
exposure on melanin
production and effect of diet
on adipose tissue
2.2
cellular control of gene
expression including
regulator, operator and
promoter genes.
Modes of inheritance and variation:
2.3
polygenic inheritance (no
dihybrid crosses)
2.4
multi-allelic (polymorphic)
inheritance.
Variation and evolution
Gene pools – changes in allele
frequencies due to:
2.5
mutation
2.6
natural selection
2.7
random genetic drift
including Founder effect
2.8
migration
© WestOne Services 2009
SCIENCE1218
3
Content cells
2.9
barriers to gene flow
eg geographical and cultural
2.10
incidence of genetic diseases
in various populations eg
Tay-Sachs disease.
Speciation and evidence
for evolution
Variation and gene pools
Module 2 Variation – the
spice of life!
Gene expression
Disruption to
homeostasis
Homeostasis
Communication – The
endocrine system
Unit content
Communication – The
nervous system
Module 1 Maintaining the
balance
Speciation:
2.11 theory of evolution by
natural selection
Evidence for evolution:
2.12
comparative studies of DNA,
protein sequences, anatomy
including embryology,
homologous and vestigial
organs
2.13
the fossil record:

fossil formation

geological dating and its
limitations

relative dating including
stratigraphy, index
fossils and fluorine
dating

absolute dating
including C-14 dating
2.14
awareness of problems with
the fossil record.
3.
The practice of human biology
Approaches to investigating and
communicating human biology
3.1
use a problem identified by
the student to formulate an
hypothesis
3.2
plan and condust a safe and
ethical investigation
incorporating two different
methods to collect data
© WestOne Services 2009
SCIENCE1218
4
Content cells
3.3
simple analysis of results
including factors that
influence the investigation,
rates, percentages and
frequencies
3.4
refer to other researchers’
findings to analyse and
report data using a variety
of sources of supporting
evidence and scientific
concepts.
Speciation and evidence
for evolution
Variation and gene pools
Module 2 Variation – the
spice of life!
Gene expression
Disruption to
homeostasis
Homeostasis
Communication – The
endocrine system
Unit content
Communication – The
nervous system
Module 1 Maintaining the
balance
The relevance of human biology
to everyday life
Control of homeostatic dysfunction
and hormone replacement therapies
to assist treatment of:
3.5
hyper/hypothyroidism
3.6
control of reproduction and
menopause
3.7
diabetes
3.8
risks, ethical concerns and
benefits associated with
interventions.
© WestOne Services 2009
SCIENCE1218
5
Investigation (20%)
Scenario
questions
(5%)
Tests and examinations (60%)
Notional hours
© WestOne Services 2009
Speciation and evidence
for evolution
Variation and gene pools
Long-term investigation (10%)
Lab cell
membran
e (3%)
Response [extended] (20%)
Gene expression
Disruption to
homeostasis
Homeostasis
Communication – The
endocrine system
Assessment types
Communication – The
nervous system
Assessment weightings
4
Lab
polygenic
inherit.
(3%)
Written
task
(5%)
Ethical
written
task
(5%)
Test –
topics 1,
2
(5%)
Test –
topics 3,
4
(5%)
7
SCIENCE1218
9
8
Lab
dating
fossils
(4%)
Gene
pool ext
ans
(5%)
Test –
topics 5,
6, 7
(10%)
7
8
9
6