BIOL 345 Anatomy and Physiology I (Nervous and Endocrine Systems) Spring, 2011 Course Syllabus Instructor: Office: Phone: E-mail: Bob Rosenberg, Professor of Biology Stanley 133 765-983-1464 rosenbo@earlham.edu Lecture: Lab: Office hours: Drop-in: TR 8:30-9:50, Dennis 014 R 1:00-5:00 Stanley 034 and Stanley 052 W 2:30-6:00 and evenings as requested, Stanley 133 Please feel free to drop by my office anytime. If I’m busy with something else, I’ll ask to schedule an appointment. E-mail questions anytime. I try to respond quickly. If your questions require a lot of words or drawing on the board, I may ask to schedule a get-together. E-mail Required texts: Vander’s Human Physiology, 12th edition, by Widmaier, Raff, and Strang (McGraw Hill, 2011). This textbook was chosen for its in-depth text, up-to-date information, and adequate figures. It has the appropriate level of detail for this course. It is more accurate and has fewer errors than other physiology texts. (You’d be surprised at some of the mistakes in many textbooks.) The 12th edition is new this year. The 11th edition is an acceptable alternative. The page numbers are different, but the content is close enough. The reading assignment pages are for the 12th edition, but the equivalent pages in the 11th edition should be easy to figure out. The Anatomy Coloring Book 3rd edition, by Kapit and Elson (Benjamin Cummings, 2002). This text was chosen because the act of coloring the names and structures helps you learn them. The text is focused and informative, so the small-print texts are part of the “coloring” assignments. This is not a kids’ book; many medical students use it to help them learn (and re-learn) anatomy. Additional text resources (on reserve in the Science Library): Medical Physiology by Boron and Boulpaep. This is a massive reference book. Use it to look up a specific detail or to answer a specific question. The answer is there! Atlas of Human Anatomy (4th edition) by Netter. This is the “bible” of human anatomy. Use it to look up a specific detail or to answer a specific question. The answer is there! Course Objectives: Physiology is the study of the function of biological systems (i.e. “how it works”). Anatomy is the study of the structure of biological systems (i.e. “how it is put together”). Understanding the anatomy of a system is often helpful in understanding its physiology, and vice versa. The goal of this course is to understand more about the structures and functions of the human body, focusing on the nervous system, skeletal muscle, and cardiovascular system. Other essential systems (respiratory, urinary, digestive, and endocrine) are covered in BIOL 347. Course Philosophy: Why study human anatomy and physiology? Each of you has reasons, but two may be at the top of your list: (1) To understand the interesting and beautiful structures of your body and how they work (i.e. to understand the physical “you”); and (2) To help you prepare for entrance exams and graduate study in biomedical research or programs in medicine, dentistry, nursing, physical therapy, and others health-related careers. 1 Human physiology and anatomy constitute an enormous amount of material. You will be expected to learn many new anatomical and physiological terms. This is similar to learning a whole new language. In many cases I use the “immersion” approach to the language; I will use the terminology, and if I say something that you don’t understand from the context, I expect you to ask questions. You will also learn many new physiological concepts, some of which are difficult to understand and master. Thus, it is important that you keep up with the material. Read, take notes, color, do problems, and/or review lecture notes every day. Falling behind and then cramming for tests will not be successful. I strongly recommend that you form a small study group that meets regularly. Explaining the material to each other is an excellent way to learn it. If you are falling behind and not doing well on quizzes and exams, please meet with me – I may have suggestions for how to study the material and prioritize it. Reading and Coloring Assignments: Reading and anatomy assignments should be done when assigned. That way you can identify what you don’t understand and make sure I clarify those concepts in class. Most reading assignments are reasonable in length, so you should be able to keep up. You are responsible for key information in the text even if I didn’t cover it in detail in class. Although I will not collect the coloring assignments, you should actually color the assigned pages. This is a form of “active learning.” You are expected to know the content of the assigned pages in the Coloring Book (including the text) whether you color the pages or not. Your coloring aesthetic and ability to color inside the lines will not be evaluated. Using multiple neural pathways (e.g. reading, hearing, writing, explaining, coloring, etc.) for the same set of information helps you learn and master it. Use multiple learning strategies! Problem Sets: There is an ancient Chinese proverb: “I hear, and I forget; I see, and I remember; I do, and I understand.” Problems are designed to help you understand the material by challenging you to “do” stuff with it. You may work with other students, but you should write your own answers. If you work with others, please indicate on your answers who you worked with. Please contact me if you would like clarification or guidance on any question – I’m happy to help because I want you to learn from doing the problems and answering the questions. Don’t wait until the deadline is looming to start working on the problem sets because some problems may take some time to figure out. Late problem sets will be penalized 10% for each day late. If you have a good reason why your problem set will be late, and we discuss it before the deadline (in person or via email), I am likely to give you a no-penalty extension. Course Grading: The grading rubric for the course is below. Exams will be in-class, closed-book. Quizzes will be self-scheduled in the science library, closed book (~30 minutes). I try to focus questions on important information and concepts and try not to focus on minor details. But it may be difficult for you to separate significant points of information from minor details, and I welcome your questions. You should save all your quizzes, exams, and problem sets in case there is a question about your final grade. Section exams (3 @ 150) 450 Final exam (cumulative) 150 Quizzes (4 @ 40) 160 Problem sets (3 @ 40) 120 Lab participation 120 Total 1000 2 You will notice that there are five quizzes on the schedule but only four in the grading rubric. That’s because under some circumstances (see below) your lowest quiz grade will be dropped from the final course grade calculation. However, in order for a quiz grade to be dropped, you must take it and get at least a 50% on it. The “senior option” will be offered to all seniors who have a weighted course average of 80% or higher for all the other scores (section exams, all five quizzes, problem sets, and lab participation). Attendance and make-up policy: Attendance in lecture and lab is required. If you miss a lecture, it is your responsibility to obtain class notes from another student. If you miss a lab due to illness or emergency, it is your responsibility to tell me why and reschedule the missed activities with me within a week. If you know ahead of time that you will miss a lab for legitimate reasons, it is your responsibility to contact me as soon as possible to make arrangements. You are allowed one unexcused absence from lab. After that, 20 points will be subtracted from your lab participation grade for each missed session. If you miss a quiz, problem set, or exam due to illness or emergency, please try to contact me before the deadline so we can make arrangements to re-schedule it for you. Class participation: You will get more out of the course, and will help others get more out of the course, if you raise your hand, ask your questions, state your confusion, and/or answer my didactic questions. I’m a better teacher if I respond to your questions in class. If I use terminology or concepts that I think you already know but don’t then I am not communicating well. Please don’t hesitate to speak up. I’m also happy to meet with you individually or in small groups. Disability accommodations: If you have a disability you must contact Academic Support Services (Donna Keesling) during the first two weeks of the semester. With the appropriate documentation, reasonable accommodations will be made. Academic Integrity: I entrust students to fully embrace the Earlham College academic integrity policy. Please review the policy at (www.earlham.edu/handbook/student/content/academic/integrity.html). Communication: Course announcements, changes, assignments, notes, study guides, etc. will be distributed in class, via email, and/or through Moodle. It’s your responsibility to check these resources regularly. Course Evaluations: I welcome your feedback and criticism at any time. Feel free to email or talk with me about the course and what would make it better. Or leave a note in my mailbox. Formal course evaluations will be done in class on the last day. 3 BIOL 345 Anatomy and Physiology I (Nervous and Endocrine Systems) Spring, 2011 Course Schedule Week Date Subject Human Physiology (12th edition) assignment 1 1/13 Introduction / review / solute transport pp. 66-78 and 95-109 1/18 Cell signaling review – receptors, G proteins, intracellular cascades pp. 118-134 2 3 4 5 6 7 8 9 10 Anatomy Coloring Book assignment Lab No lab 1, 2, 23 1/20 Nervous system – neurons and membrane potentials pp. 135-147 15, 71, 72 1/25 Nervous system – synaptic and action potentials pp. 147-156 31, 33, 45, 56, 57 1/27 Nervous system – synapses and neurotransmitters pp. 156-169 54, 55, 58 2/1 Nervous system – molecular mechanisms and neuronal modeling pp. 169-175 27, 49, 50 2/3 Cellular neurophysiology – catch up and review 2/8 EXAM 1 2/10 Nervous system – autonomic, central, and peripheral nervous systems pp. 175-180 70, 73, 83, 93, 94 2/15 Nervous system – touch pp. 186-202 91, 88, 78 2/17 Early semester break 2/22 Nervous system – vision pp. 202-212 95, 97 2/24 Nervous system – hearing pp. 212-220 98, 99 3/1 Nervous system - smell and taste pp. 220-222 100 3/3 Skeletal muscle pp. 250-263 79, 44, 40, 61, 62, 3/8 Nervous system – motor control pp. 263-275 63, 64, 3/10 Nervous system – motor control pp. 296-309 65, 66 3/15 Spring Break 3/17 Spring Break Introduction cadaver, skeleton, and computers Upper torso Upper limb PS 1 due 1/23 Upper torso Upper limb Quiz 1 due 1/30 Back and upper limb Quiz 2 due 2/6 Sheep brain Upper limb No lab Quiz 3 due 2/16 (Wed) Cow eye Lower limb PS 2 due 2/27 Lower limb Quiz 4 due 3/6 Lower limb No lab 4 Problem sets and quizzes 11 12 13 14 15 16 17 3/22 Nervous system – catch up and review 3/24 Endocrine – overview, anatomy, hormones 3/29 EXAM 2 3/31 pp. 311-323 51, 151 Torso Endocrine – hypothalamus and pituitary pp. 325-331 152, 153 Torso 4/5 Endocrine – pituitary and thyroid pp. 332-335 154 4/7 Endocrine – adrenal, growth hormone, and parathyroid pp. 336-348 155 4/12 Reproduction – overview, anatomy, male pp. 593-600 157, 158 4/14 Reproduction - female pp. 603-614 160, 161, 162, 163 4/19 Reproduction – pregnancy pp. 614-626 4/21 Endocrine – Catch up and review 4/26 EXAM 3 4/28 Molecular mechanisms of diseases, course evaluations 5/2 10:30 am Final Exam (Cumulative) 5 PS 3 due 4/10 Thorax Quiz 5 due 4/17 Thorax