1st
Week
2ªF
19/10/
2009
MOLECULAR AND CELLULAR BIOLOGY (Tronco Comum)
1ª Semana 19 a 23/10/2009
Morning
Afternoon
1.Molecules and Cells I:
9:00 - Plenary session 1:
Genomic diversity and gene expression
(Carolino Monteiro)
11:00 - Plenary session 2: The RNA
world (Cecilia Arraiano)
3ªF
20/10/
2009
4ªF
21/10/
2009
5ªF
22/10/
2009
6ªF
23/10/
2.Molecules and Cells II:
9:00 - Plenary session 3: Cell
trafficking (Joana Melo)
11:00 - Plenary session 4: Protein
degradation and autophagy (Sandra
Cardoso)
3.Cell Signalling I:
9:00 – Group work
14:00 - 1.Molecules and Cells I:
(Articles presentation and discussion by students with
Guest Speakers and Coordinator)
1- Polyglycine expansions in eRF3/GSPT1 are
associated with gastric cancer susceptibility.
Carcinogenesis vol.26 no.12 pp.2046–2049, 2005
doi:10.1093/carcin/bgi168. Advance Access publication June 29,
2005. (CM)
2- DMBT1 is frequently downregulated in welldifferentiated gastric carcinoma but more frequently
upregulated across various gastric cancer types
International Journal Of Oncology 30: 1441-1446,
2007(CM)
3- Switching from Repression to Activation:
MicroRNAs Can Up-Regulate Translation. Science
318, 1931 (2007). Shobha Vasudevan, et al.
The Two Faces of miRNA. J. Ross Buchan and Roy
Parker. Science VOL 318 21. December 2007. 1877- 8.
(CA)
4- The exosome contains domains with specific
endoribonuclease, exoribonuclease and cytoplasmic
mRNA decay activities Nature Structural & Molecular
Biology Advance Online Publication
doi:10.1038/nsmb.1528
mRNA decay Cutting in the middle Nature Reviews
Molecular Cell Biology | AoP, published online 15
January 2009; doi:10.1038/nrm2623 (CA)
14:00 - 2.Molecules and Cells II:
(Articles presentation and discussion by students with Guest
Speakers and Coordinator)
5- Roles of mitophagy and the mitochondrial
permeability transition in remodeling of cultured
rat hepatocytes (SC)
14:30 – Plenary session 6: Cell cycle regulation (C
Sunkel)
11:00 - Plenary session 5: Cell
signalling-An overview (Ana Bela
Sarmento)
16:00 - Plenary session 7: Control mechanisms during
cell division (C Sunkel)
4.Cell Signalling II:
11:00 - Plenary session 9- Oxidative
stress in health and disease (Cláudia
Pereira)
14:00 - 3.Cell Signalling I: Applications
(Articles presentation and discussion by students with Guest
Speakers and Coordinator)
6- Loss of PINK1 causes mitochondrial functional
defects and increased sensitivity to oxidative stress
(CP)
7- FK506 can activate transforming growth factor-b
signalling in vascular smooth muscle cells and promote
proliferation. Cardiovascular Research (2008) 79,
519–526 (AS)
9:00 - 4.Cell Signalling II:
(Articles presentation
(Articles presentation and discussion by students with Guest
Speakers and Coordinator)
9:00 – Group work
2009
and discussion by students with Guest
Speakers and Coordinator)
11:00 - Plenary session 8- Epigenetic
and gene regulation (Jaspal Kaeda)
8- AGUARDA ENVIO DE ARTIGO (JK)
16:00 SEMINAR – title to be announced
Jaspal Kaeda
MOLECULAR AND CELLULAR BIOLOGY (Tronco Comum)
2ª Semana 26 a 30/10/2009
2nd
week
2ªF
26/10
2009
3ªF
27/10
2009
4ªF
28/10
2009
5ªF
29/10
2009
Manhã
5.Biology of the Nucleus I:
9:00 - Plenary session 10: Chromosomal
Behaviour in meiosis and mitosis and
biological mechanisms of its errors.
(Isabel M Carreira)
11:00 - Plenary session 11: Implications
of meiotic and mitotic errors in fertility,
mental retardation and cancer. (Isabel M
Carreira)
6. Biology of development I:
9:00 - Plenary session 11
A-Cell differentiation (João Malva)
9:45 - Plenary session 12
B-Developmental biology: bone tissue
(Helena Figueiredo)
11:00 - Plenary session 13
C- Genomic imprinting (Jorge Saraiva)
11:30 - Plenary session 14D-RNA in the embrionic development (I
Palmeirim)
Tarde
Group work
14:00 - 6. Biology of development I:
(Articles presentation and discussion with Guest
Speakers and Coordinator).
1- Neuropeptide Y Promotes Neurogenesis in
Murine Subventricular Zone. STEMCELLS
2008;26:1636–1645 (JM9
2-The diamond concept – open questions Injury,
Int. J. Care Injured (2008) 39S2, S5–S8 (HF)
3- Maternally Inherited Birk Barel Mental Retardation
Dysmorphism Syndrome Caused by a Mutation in the
Genomically Imprinted Potassium Channel KCNK9.
The American Journal of Human Genetics 83, 193–199,
August 8, 2008 (JS)
4- AGUARDA ENVIO DE ARTIGO (IP)
7. Cellular and Molecular Biology
techniques I – Applications
9:00 - Plenary session 15: Security and
Quality Lab control
7. Cellular and Molecular Biology techniques I
– Applications
11:00 - Lab work
7. Cellular and Molecular Biology
techniques I – Applications
Discussion of lab work results
8.Biology of the Nucleus II:
14:00 - Plenary session 16: Why are certain
structural aberrations more frequent than others?
(Orseta Zuffardi)
9:00 - Discussion of lab work results
(cont)
14:00 - Lab work
16:00 - Plenary session 17: Genome-wide array
and prenatal diagnosis. (Orseta Zuffardi)
6ªF
30/10
2009
8. Biology of the Nucleus II:
(Articles presentation and discussion with
Guest Speaker and Coordinator).
5- A systematic, large-scale resequencing
screen of X-chromosome coding exons in
mental retardation. Nature Genetics
Volume 41(5). May 2009. (OZ)
6- Origins and functional impact of copy
number variation in the human genome.
doi:10.1038/nature08516.
Sharp focus on the variable genome. Nat
Vol 461|8 October 2009. (OZ)
7- Duplications of noncoding elements 5′
of SOX9 are associated with
brachydactyly-anonychia. volume 41 |
number 8 | august 2009 | nature genetics
Duplications of non-coding elements 5´
of SOX9 are associated with
brachydactyly/anonychia
I Kurth, E Klopocki, S Stricker, J van
Oosterwijk, S Vanek, J Altmann, H G.
Santos, J van Harssel, T de Ravel, A
O.M. Wilkie, A Gal and S Mundlos
Supplementary Methods (OZ)
8- Mutation of FOXL2 in Granulosa-Cell
Tumors of the Ovary.N engl j med 360;26
nejm.org june 25, 2009
Cancer Genomes on a Shoestring Budget.
n engl j med 10.1056/nejme0903433 pg12 (OZ)
SEMINAR: Genomic variation: a
continuous from SNPs to chromosome
aneuploidy. Orseta Zuffardi