CURRICULUM VITAE
Jan Nedergaard
CURRICULUM VITAE: Jan Nedergaard
Professional address: The Wenner-Gren Institute. Stockholm University
SE-106 91 Stockholm, Sweden
PhD-degree : 1980: The Wenner-Gren Institute, Stockholm University,
PhD in Zoological Physiology
Control of fatty acid utilization in brown adipose tissue Thesis:
Docent :
Current position :
1982: Stockholm University, in Zoological Physiology
Full Professor in Physiology, The Wenner-Gren Institute, Stockholm
University, since 1999
Previous positions : 1994-1998: Professor, The Wenner-Gren Institute, Stockhol University
1984-1994: Associate Professor, The Wenner-Gren Institute,
Stockholm University
1981-1984: Assistant Professor, The Wenner-Gren Institute,
Stockholm University
1981 and 1985, 6 months at each occasion Parental leaves :
Current research activities: The physiology of thermogenesis
Awarded doctorates: Since 1984, 17 PhD:s (main supervisor)
Since 1984, 14 PhD:s (co-supervisor)
Currently supervisor for 4 PhD-students
Postdoc working or worked in Cannon/Nedergaard’s research group: 26, since 1983
Major running scientific grants:
2011-2013 PI VR-NT 3 300 kkr
2009-2011 PI VR-M 1 200 kkr
2008-2012 Co-PI EU-ADAPT 445 k€
2009-2011 Co-PI Mitotech 1 250 kkr
2011 PI Metabolic Solutions 900 kkr
National and international assignments of importance :
Since 2003: Member of the National Committee of Physiology, Pharmacology and
Neurobiology; Secretary of the Committee since 2008
2003-2008: Dean of the Subfaculty of Biology, Stockholm University
2003-2008: Chairman of the Faculty Appointments Committee;
Member of the Committee 1990-1993
1993-2002: Chairman of the Faculty Docent Committee
1989-1995: Member of the Biology Committee of the Swedish Natural Science Research
Council
CURRICULUM VITAE
Jan Nedergaard
Bibliometric data: about 150 primary articles and of about 100 review articles and book chapters. H-index 45. Number of citations: 6879
Total citations during 2010: 744
Ten selected publications (from the last 10 years):
Petrovic, N., Walden, T.B., Shabalina, I.G., Timmons, J.A., Cannon, B. and Nedergaard, J. (2010) Chronic activation of epididymally derived white adipocyte cultures reveals a population of thermogenically competent,
UCP1-containing adipocytes molecularly distinct from classical brown adipocytes. J. Biol. Chem. 285, 7153-7164.
Feldmann, H.M., Golozoubova, V., Cannon, B. and Nedergaard, J. (2009) UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutrality. Cell Metab.
9, 203-209.
Timmons, J.A., Wennmalm, K., Larsson, O., Walden, T.B., Lassmann, T., Petrovic, N., Hamilton, D.L., Gimeno, R.
E., Wahlestedt, C., Baar, K., Nedergaard, J. and Cannon, B. (2007) Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proc. Natl. Acad. Sci. USA 104, 4401-4406.
Nedergaard, J., Bengtsson, T. and Cannon, B. (2007) Unexpected evidence for active brown adipose tissue in adult humans. Am. J. Physiol . 293, E444-E452.
Golozoubova, V., Cannon, B. and Nedergaard, J. (2006) UCP1 is essential for adaptive adrenergic nonshivering thermogenesis. Am. J. Physiol .
291, E350-E357
Shabalina, I.G., Jacobsson, A., Cannon, B. and Nedergaard, J. (2004) Native UCP1 displays simple competitive kinetics between the regulators purine nucleotides and fatty acids . J. Biol. Chem. 279,
38236-38248.
Cannon, B. and Nedergaard, J. (2004) Brown adipose tissue: function and physiological significance. Physiol. Rev .
84, 277-359.
Golozoubova, V., Hohtola, E., Matthias, A., Jacobsson, A., Cannon, B. and Nedergaard, J. (2001) Only UCP1 can mediate adaptive nonshivering thermogenesis in the cold. FASEB J . 15, 2048-2050.
Matthias, A., Ohlson, K.B.E., Fredriksson, J.M., Jacobsson, A., Nedergaard, J. and Cannon, B. (2000) Thermogenic responses in brown-fat cells are fully UCP1-dependent. UCP2 or UCP3 cannot substitute for UCP1 in adrenergically or fatty-acid induced thermogenesis. J. Biol. Chem . 275, 25073-25081.
Fredriksson, J.M., Lindquist, J.M., Bronnikov, G.E. and Nedergaard, J. (2000) Norepinephrine induces vascular
-adrenoceptor/cAMP/protein kinase A pathway involving Src but independently of Erk1/2. J. Biol. Chem.
275, 13802-13811.