BIOGRAPHICAL SKETCH
NAME
POSITION TITLE
Casimir A. Kulikowski
Board of Governors Professor of Computer Science
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION
Yale University, New Haven, CT
Yale University, New Haven, CT
University of Hawaii, Honolulu, HI
DEGREE
(if applicable)
YEAR(s)
FIELD OF STUDY
B.E.
M.S.
Ph.D
1965
1966
1970
Electrical Engineering
Engr. & Applied Science
Electrical Engineering
A. Positions and Honors. List in chronological order previous positions, concluding with your present
position. List any honors. Include present membership on any Federal Government public advisory
committee.
Professional Experience
1970-1973
1973-1977
1977-1997
199719801983-1991
19841984-1987
1984-1990
1985-1994
1985-1996
1988-1992
Assistant Professor of Computer Science
Associate Professor of Computer Science
Professor of Computer Science
Board of Governors Professor of Computer Science
Editorial Board, Computers in Biology and Medicine
Director, Rutgers Research Resource on AI in Medicine
Member, Graduate Faculty in Biomedical Engineering
Board of Scientific Counselors, National Library of Medicine, NIH
Chairman, Department of Computer Science
Editorial Board of Expert Systems: Research and Applications
Director, Laboratory for Computer Science Research
Committee on Review, Social Security Administration Systems Modernization, Bd. on
Telecomm. and Computer Applications, National Research Council
1993-1997 National Advisory Board, NJ Comprehensive Immunization Project
1993-1998 Editorial Board, Journal of the American Medical Informatics Association
1997-1999 Chair, Biomedical Library Review Committee, National Library of Medicine,
NIH. (Member, 1994-97).
1999Editorial Board, Methods of Information in Medicine
2000Co-Editor, Yearbook of Medical Informatics-Int Med Inf Assoc (IMIA)
2001 Associate Editor, Artificial Intelligence in Medicine Journal
2002 - 2004 BIOINFOMED Advisory Committee to the European Commission
2003
BISTIC Advisory Committee to the NIH
2002Committee on Emerging Issues and Data on Environmental Contaminants, NRC-NAS
2004
Co- Chair, Scientific Program Committee, World Congress of Medical Informatics
(Medinfo 2004).
Honors, Awards and Memberships
Member, Institute of Medicine of the National Academy of Sciences (IOM)
Fellow, Institute of Electrical and Electronics Engineers (IEEE),
American Association for the Advancement of Science (AAAS)
Founding Fellow, American College of Medical Informatics (ACMI) and
American Association of Artificial Intelligence (AAAI)
Prize Scientific Exhibit - American Academy of Ophthalmology
Fellow. American Institute of Medical and Biological Engineering (AIMBE)
B. Original Publications:
Nordyke RA, Kulikowski CA, Kulikowski CW. A Comparison of Methods for the Automated Diagnosis of
Thyroid Dysfunction. Comp. Biomed. Res., 4:374-389 (1971).
Weiss S, Kulikowski CA, Safir A. Glaucoma Consultation by Computer. Comp. Biol. and Med., 8:25-40
(1978)
Weiss S, Kulikowski C, Amarel S, Safir A. A Model-based Method for Computer-aided Medical Decision
Making, Journal of Artifical Intelligence, 11:145-172 (1978).
Weiss S, Kulikowski C. EXPERT: A System for Developing Consultation Models. Proc. Sixth
International Joint Conference on Artificial Intelligence, Tokyo, pp. 942-947 (1979).
Kulikowski CA. Artificial Intelligence Methods and Systems for Medical Consultation. IEEE Trans. on
Pattern Analysis and Machine Intelligence, PAMI-2, 5:464-476 (1980).
Kulikowski CA and Weiss SM. Representation of Expert Knowledge for Consultation: The CASNET and
EXPERT Projects. Ch. 2 in Artificial Intelligence in Medicine (P. Szolovits, ed.), pp.21-55, AAAS
Selected Symposia Series, Westview Press, Boulder, CO, (1982).
Weiss SM, Kulikowski CA, Galen RS. Representing Expertise in a Computer Program: The Serum Protein
Diagnostic Program. J. Clin. Lab. Automation, 3:383-387 (1983).
Lindberg DAB, Sharp GC, Kay DR, Kingsland LC, Roeseler G, Kulikowski CA Weiss SM. The Expert
Consultant as Teacher. Moebius, 3:30-36 (1983).
Kastner JK,Dawson CR., Weiss SM, Kern K B, Kulikowski CA. An Expert Consultation System for
Frontline Health Workers in Primary Eye Care. J. Med.Sys. 8:389-397 (1984).
Weiss SM and Kulikowsi CA. A Practical Guide to Designing Expert Systems, Rowman & Allanheld,
Totowa, NJ, (1984).
Kulikowski CA. Domain Knowledge, In Encyclopedia of Artificial Intelligence (S. Shapiro, ed.), J.WileyInterscience, pp.251-253 (1987).
Zimmerman DE, Kulikowski CA, Wang L, Lyons B, Montelione G. Automated Sequencing of Amino Acid
Spin Systems in Proteins Using Multidimensional HCC(CO)NH-TOCSY Spectroscopy and Constraint
Propagation Methods from Artificial Intelligence. J. Biomolecular NMR, 4: 241-256, (1994).
Kulikowski CA and Gong L. Medical Imaging Informatics in the Age of High Performance Computing.
Yearbook of Medical Informatics, North-Holland, Amsterdam, pp.61-68 (1994).
Cohen D, Kulikowski CA, Berman H. Automated Generation of Machine Learning Experiments in
Training Data Selection: A Knowledge-Based Approach to Learning DNA Hydration Pattern Predictors.
Machine Learning, 21:81-101 (1995),.
Kulikowski CA, Gong L, Mezrich RS. Knowledge-Based Medical Image Analysis and Representation for
Integrating Content Definition with the Radiological Report. Methods of Information in Medicine,
34:96-103 (1995).
Gong L and Kulikowski CA. Composition of Image Analysis Processes through Object-Centered
Hierarchical Planning. IEEE Trans.Pattern An. & Machine Intelligence PAMI-17:997-1009 (1995).
Kulikowski CA. The Scope of Medical Informatics as Art and Science. Methods of Information in
Medicine 3:185-188 (1996).
Kulikowski CA and Gong L. Advances in Image Processing. In: Handbook of Medical Informatics, (J.
H.van Bemmel and M.A. Mussen, eds.) Springer, Heidelberg pp.413-422 (1997).
Kulikowski CA. Medical Imaging Informatics: Challenges of Definition and Integration. JAMIA 4:252253, (1997).
Zimmerman DE, Kulikowski CA, Huang Y, Feng W, Shimotakahara S, Chien C, Powers R, Montelione GT.
Automated Analysis of Protein NMR Assignments Using Methods from
Artificial Intelligence. J.
Mol Biol, 269:592-610, (1997).
Gelfand I., Kister, A., Kulikowski C, Stoyanov O. Geometric Invariant Core for the Vl and Vh Domains of
Immunoglobulin Molecules. Protein Eng, 11:1015-1025, (1998).
Poe X, Kulikowski CA, Muchnik, I., Dubchak, I., Wolf, D., Spengler, S., Zorn, M., Analysis of Ribosomal
RNA Sequences by Combinatorial Clustering, Proc 7th Int Conf Intell Systems in Molecular Biology
(ISMB'99)", 287-296, (1999).
Hagerty CG, Muchnik, I, Kulikowski C, Kim S-H. Two indices can approximate four hundred and two
amino acid properties. Proc IEEE Int Conf on Automatic Control/Intelligent Systems & Semiotics",
365-369, (1999.
Kulikowski CA. Synopsis: Image and Signal Processing. Yearbook of Medical Informatics: The Promise
of Medical Informatics (J.H. van Bemmel and A. McCray, eds.), Schattauer, Stuttgart, 429-432, (1999).
Kulikowski CA. Artificial Intelligence in Medicine: History, Evolution, and Prospects, in Handbook of
Biomedical Engineering, 2nd Ed. (J. Bronzino, Ed.), CRC Press & IEEE Press Boca Raton, FL, 181.1181.19, (2000).
Muchnik I, Kulikowski C. Montelione GT. Structural Domain Parsing from Protein Sequences. Proc Int
Math Mod Sim Conf (IMACS-2000)
Chang S, Kulikowski CA., Dunn SM, Levy S, Weisel J. Skeletonization of Fibrin Networks. Proc
Microscopy and Microanalysis (2000)
Hagerty CG, Pickens D Kulikowski CA, Sonnenber FA. HGML: A Hypertext Guideline Markup Language.
Proc Annual AMIA Symposium, (2000)
Stoyanov O, Kister, A, Gelfand, I, Kulikowski, C, and Chothia, C, Geometric invariant core for the
Cl and Chl domains of immunoglobulin molecules, J Comp. Biol. 7:673-684, 2000
Kulikowski CA The Micro-Macro Spectrum of Medical Informatics Challenges : From Molecular
Medicine to Transforming Health Care in a Globalizing Society, Meth Inform Medicine
41:20-24; 2002
Genkin A, Kulikowski CA, Muchnik I, Set covering submodular maxiomization: An optimal
algorithm for data mining in bioinformatics and medical informatics, J Intel & Fuzzy Systems
12(1):5-17 (2002)
Haux R Kulikowski CA, Editorial: Quality of Health Care: The Role of Informatics, In: 2003
IMIAYearbook of Medical Informatics , International Medical Informatics Association,
Schattauer Pub, Stuttgart, 2003, pp. 5-7
Maojo V, Kulikowski C, Bioinformatics and medical informatics: Collaborations on the road to
genomic medicine? J Amer Med Infor Assoc 10(5):512-514 (2003).
Kulikowski CA Stefanelli M Editorial: Medinfo 2004 – An opportunity to shape the future course
of Medical Informatics together Meth Inform Medicine 2004 43:122-123.
Kulikowski, CA Haux H Editorial: The Road to Clinical Bioinformatics IMIA Yearbook of
Medical Informatics 2004 Schattauer, Stuttgart, 3-5.
Martin-Sanchez F Iakovidis I Norager S Maojo V deGroen P van der Lei J Jones T AbrahamFuchs K Apweiler R Babic A Baud R Breton V Cinquin P Doupi P Dugas M Eils R Engelbrecht E
Ghazal P Jehenson P Kulikowski C Lampe K De Moor G Orphanoudakis S Rossing N Sarachan B
Sousa A Spekowius G Thireos G Zhlmann G Zvarova J Hermosilla I Vincente FJ Synergy
between medical informatics and bioinformatics: facilitating genomic medicine for future health
care J Biomedical Informatics 2004, 37:30-34.
Knaup P, Amenwerth E, Brandner R, Brigl B, Fischer G, Garde S, Lang E, Pilgram R, Ruderich F, Singer R,
Wolff AC, Haux R, Kulikowski C, Towards clinical bioinformatics: Advancing genomic medicine with
informatics methods and tools Meth Inform Medicine 43(3):302-307 (2004)
Vashisht A Muchnik I Kulikowski CA Target Sequences for new protein structures using
automatic screening for ortholog clusters in a set of genomes Proc Int Conf on Structural
Genomics, Washington DC, Nov 2004.