Public Health Surveillance of Illness Related to Harmful Algal Blooms: Florida's Experience Harmful Algal Blooms (HABs) occur throughout the world with Florida having the distinction of being home to all major toxin-producing marine, estuarine and freshwater microalgae. The subtropical warm climate, 1200 miles of coastline, varied aquatic habitats, and the human interface through seafood consumption and from water activities compose an environment where the presence of aquatic toxins can have a significant impact on public health. During the past 2 decades there has been a dramatic increase in the population along Florida’s coastline; 80% of the population lives near the coast and greater numbers either vacation or participate in recreational activities at the shore. Coincident with this increase in population, has been an apparent increase in frequency and distribution of toxic blooms. The increased reliance of the state on tourism for its economic health together, with an increasing population at risk for exposure to HABs makes the assessment of health related illness from aquatic toxins an important and emerging public health issue. Florida is fortunate that there are surveillance and reporting systems that offer the opportunity for the identification and description of HAB related illness. The Florida Poison Information System, the Florida Department of Health Reportable Disease Network (Merlin) and the syndromic surveillance system (ESSENCE) provide a mechanism for documenting health impacts from human exposures to HABs including Karenia brevis red tides, ciguatera fish poisonings, saxitoxin related poisonings, and cyanobacteria (blue green algae) associated illness. These reports are now tracked and collated using the newly implemented CDC Harmful Algal Bloom Illness Surveillance System (HABISS). HABISS is the innovative system that uniquely provides a federal perspective for HAB related illness in the US with a centralized system. This presentation will address the implementation of a statewide HAB surveillance effort including historically important illness (such as neurotoxic shellfish poisoning) and newly emerging illness (brevetoxin associated respiratory illness, cyanobacteria related illness). The linkage to the CDC HABISS system will be highlighted including use by public health managers for response decision making and collaborations across state boundaries. The importance of including HAB related illness as part of comprehensive public health illness surveillance and reporting system will be emphasized including development of partnerships between local, state, and federal entities.