ACP’s Antibiotics for Acute Respiratory Tract Infections paper Embargoed until 5:00PM Eastern January 18, 2016 Embargoed for release until 5:00 p.m. Eastern Time on Monday, January 18, 2016 (1) Announcer: Respiratory tract infections are the most common reason for outpatient antibiotic prescriptions for adults. But an estimated 50 percent of prescriptions may be unnecessary or inappropriate. The American College of Physicians and the Centers for Disease Control and Prevention offer advice for prescribing antibiotics in a new paper. Dr. Tanveer Mir, Chair, Board of Regents, American College of Physicians (2) Dr. Tanveer Mir: Inappropriate use of antibiotics for conditions like the common cold, acute sinusitis, acute bronchitis or sore throat leads to adverse drug reactions and antibiotic resistance. This accounts for about two million illnesses a year and twenty-three thousand deaths, which is a public health hazard. (3) Announcer: It is estimated that 5 to 25% of patients who take antibiotics will have adverse events, and about 1 in 1,000 will have a serious adverse event. (4) Dr. Tanveer Mir: Antibiotics are responsible for the largest number of adverse drug reactions. One in five emergency room visits are attributed to antibiotic reactions. (5) Announcer: ACP and the CDC advise doctors to educate patients and reassure them that they likely will get better without antibiotics. (6) Dr. Tanveer Mir: Patient education is so important because patients need to understand that symptom-based therapies or simple over-thecounter medications can help them get over the common cold, get over a sinus infection or an uncomplicated bronchitis. ACP’s Antibiotics for Acute Respiratory Tract Infections paper Embargoed until 5:00PM Eastern January 18, 2016 (7) Announcer: Another strategy is for doctors to use a symptomatic prescription pad to provide recommendations for management of symptoms and offer the possibility of future antibiotic treatment if the condition fails to improve. For more information go to acponline.org. Additional soundbites Dr. Tanveer Mir Chair, Board of Regents, American College of Physicians Should physicians prescribe antibiotics for the common cold? Physicians should not prescribe antibiotics for the common cold. If the period of recovery is extended beyond two weeks then they may seek medical attention for that. Usually, symptombased therapies are the way to go for the common cold and to provide quick relief and improvement in the medical conditions. What should physicians do for uncomplicated bronchitis? For uncomplicated bronchitis, physicians should not perform testing or prescribe antibiotics unless pneumonia is suspected. Symptomatic relief with agents like antihistaminics, betaagonists, cough suppressants or even simple things like aspirin or acetaminophen may be the way to go. What should physicians do for sore throat? For sore throat, physicians should recommend analgesic therapy like aspirin, acetaminophen, non-steroidals, anti-inflammatory agents or throat lozenges to minimize pain. What is the usual course for a sore throat and what should a physician do to reassure patients about treatment with antibiotics? Physicians should reassure patients that sore throat routinely lasts less than one week and the use of antibiotics is not indicated. This leads to a larger number of side effects without improving the condition. What should physicians do for streptococcal pharyngitis? When streptococcal pharyngitis is confirmed by rapid strep assay or by a culture that is positive for group A streptococcus, antibiotics are indicated. What should physicians do for sinus infection? Uncomplicated sinus infection does not require antibiotics. The majority of patients with uncomplicated sinus infections may suffer from side effects rather than benefit from antibiotic therapy. Supportive management is indicated in the management of uncomplicated sinus ACP’s Antibiotics for Acute Respiratory Tract Infections paper Embargoed until 5:00PM Eastern January 18, 2016 infections. When should physicians use antibiotic treatment for sinus infection? Physicians should reserve antibiotics in the management of sinus infection when symptoms are persistent for ten days or more or severe symptoms are noted for three days or more that consist of high fever, facial pain, and nasal discharge. In addition, if a viral illness that was improving initially continues for five days or more, antibiotics may be indicated as well. What is a symptomatic prescription pad and how can it be used? A symptomatic prescription pad can be used to provide recommendations for symptomatic relief and the possibility of future antibiotic use if symptoms don’t improve. So physicians can use simple terminologies like you know, the common cold, which makes it very common and something that patients would accept. For bronchitis they can call it a simple chest cold or they can call it a viral upper respiratory tract infection. Once we start using those terminologies, patients are a little more comfortable and they better understand what the condition is and the use of symptom-based therapies rather than antibiotics becomes more acceptable to them. Courtesy the American College of Physicians, publisher of Annals of Internal Medicine ###