麻醉
科
師資陣容
戴元基
實驗室分機
請向系上詢問
English Name
職稱
Yuan-Ji Day
副教授主治醫師
實驗室位置
請向系上詢問
Title
畢業學校
（一）美國維吉尼亞大學
School
（一）University of Virginia, USA
學位
（一）博士及碩士
Center
（二）醫學士及碩士
Degree
畢業年次
（一）PhD and MS
（二）MD and MS
（一）2003, 2000
（二） 1984, 1986
Year of graduation
（一）
（二）
研究領域
發炎機制,幹細胞, 基因轉殖, 遺傳,麻醉生理藥理
Research Topic
Inflammation, stem cell, gene targeting, genetic immunology, Anesthesiology
（二）國防醫學院
（ 二 ） National Defense Medical
近五年發表
1.
2.
3.
4.
Li Y, Oskouian RJ, YJ Day, Kern JA, Linden J: Optimization of a Mouse
Locomotor Rating System to Evaluate Compression-Induced Spinal Cord Injury:
Correlation of Locomotor and Morphological Injury Indices. J Neurosurg Spine,
4(2):165-173, 2006. (IF=2.577)
YJ Day, Huang L, Ye H, Li L, Linden J, Okusa MD: Renal Ischemia-Reperfusion
Injury and Adenosine 2A Receptor-Mediated Tissue Protection: The Role of CD4
T Cells and Interferon gamma. J Immunology, 176(5):3108-3114, 2006.
(IF=6.702 )
Li Y, Oskouian RJ, YJ Day, Rieger JM, Liu L, Kern JA, Linden J: Mouse Spinal
Cord Compression Injury is Reduced by Either Activation of the Adenosine A(2a)
Receptor on Bone Marrow-derived Cells or Deletion of the A(2a) Receptor on
Non-bone Marrow-derived Cells. Neuroscience, 141(4):2029-2039, 2006.
(IF=3.456)
AN. Clark, R Youkey, X Liu, L Jia, R Blat, YJ Day, GW. Sullivan, J Linden, AL
Tucker: A1 Adenosine Receptor Activation Stimulates Angiogenesis through
Release of VEGF from Mononuclear Cells. (submitted)
5.
6.
7.
CM Lappas1, YJ Day, MA. Marshall, V Engelhard, J Linden: Adenosine A2A
receptor activation reduces hepatic ischemia-reperfusion injury by inhibiting
CD1d-dependent NKT cell activation. Journal of Experimental Medicine,
203:2639-48, 2006, (IF=14.588)
Yang Z, YJ Day, Toufektsian MC, Xu Y, Romas SI, Marshall M, French BA,
Linden J: Myocardial infarct-sparing effect of adenosine A2A receptor activation
is due to its action on CD4+ T-lymphocytes. Circulation, 114:2056-2064, 2006,
(IF=12.563)
Chen PL, Day YJ, Su BC, Lee PC, Chen CY: Delayed onset of
sevoflurane-induced juvenile malignant hyperthermia after second exposure. Acta
Anaesthesiol Taiwan, 45(3):189-93, 2007.
8.
YJ Day: Fallen from fame--what if anesthesiologist frauds. Acta Anaesthesiol
Taiwan, 45(3):131-34, 2007.
9.
FC Liu, JT Liou, AH. Li, HJ Chiou, YJ Day: Acute Unilateral Parotid Glands
Enlargement Following Endotracheal General Anesthesia：Report of Two Cases.
Chang Gung Med J, 30:453-7, 2007.
10. Clark AN, Youkey R, Liu X, Jia L, Blatt R, Day YJ, Sullivan GW, Linden J,
Tucker AL.: A1 Adenosine Receptor Activation Promotes Angiogenesis and
Release of VEGF From Monocytes. Circ Res,101(11):1130-1138,
2007.(IF=9.408)
11. Huang,Y.J,
Chen,I.S,
Tseng,C.P,
Day,Y.J,
Lin,Y.C,
Liao,C.H.:
(2R,3R)-2-(3',4'-dihydroxybenzyl)-3-(3'',4''-dimethoxybenzyl)
butyrolactone
suppresses fMLP-induced superoxide production by inhibiting fMLP-receptor
binding
in
human
neutrophils.
Biochem.Pharmacol.75(3):688-697,
2008.(IF=3.436)
12. Shen,H.Y.; Coelho,J.E.; Ohtsuka,N.; Canas,P.M.; Day,Y.J.; Huang,Q.Y.;
Rebola,N.; Yu,L.; Boison,D.; Cunha,R.A.; Linden,J.; Tsien,J.Z.; Chen,J.F: A
critical role of the adenosine A2A receptor in extrastriatal neurons in modulating
psychomotor activity as revealed by opposite phenotypes of striatum and
forebrain A2A receptor knock-outs. J.Neurosci. 28(12):2970-2975, 2008.(SCI)
13. Yu,L.; Shen,H.Y.; Coelho,J.E.; Araujo,I.M.; Huang,Q.Y.; Day,Y.J.; Rebola,N.;
Canas,P.M.; Rapp,E.K.; Ferrara,J.; Taylor,D.; Muller,C.E.; Linden,J.;
Cunha,R.A.; Chen,J.F: Adenosine A2A receptor antagonists exert motor and
neuroprotective effects by distinct cellular mechanisms. Ann. Neurol.
63(3):338-346, 2008.(SCI)
14. FC. Liu; YJ Day; JT. Liou; YT. Lau; HP. Yu: Sirtinol attenuates hepatic injury
and pro-inflammatory cytokine production following trauma-hemorrhage in male
Sprague-Dawley rats. Acta Anaesth Scand 52(5):635-640, 2008 (SCI)
15. Luk,H.N.; Lo,C.P.; Tien,H.C.; Lee,D.; Chen,Z.L.; Wang,F.; Hsin,S.T.; Day,Y.J.:
Mechanical characterization of rabbit pulmonary vein sleeves in in vitro intact
ring preparation. J.Chin.Med.Assoc. 71(12):610-618, 2008.
16. Liao,C.C.; Day,Y.J.; Yang,M.W.; Lin,T.S.: Neurological impairment following
myocardial ischemia associated with postoperative epidural analgesia. Acta
Anaesthesiol.Taiwan.46(4):194-198, 2008.
17. Liao,C.H.; Lin,S.Z.; Tseng,C.P.; Day,Y.J.; Chang,C.S.; Chang,Y.H.; Kuo,S.C.: A
benzodiazepines derived compound, 4-(3-chlorophenyl)-1,3-dihydronaphtho
[2,3-b][1,4]diazepin-2-one (ND700C), inhibits fMLP-induced superoxide anion
release by activating protein phosphatase 2A in human neutrophils.
Biochem.Pharmacol.76(12):1728-39, 2008.
18. Liu,F.C.; Liao,C.H.; Chang,Y.W.; Liou,J.T.; Day,Y.J.*: Splitomicin suppresses
human platelet aggregation via inhibition of cyclic AMP phosphodiesterase and
intracellular Ca++ release. Thromb.Res.124: 199-207, 2009.
19. Liu,F.C.; Day,Y.J.; Liao,C.H.; Liou,J.T.; Mao,C.C.; Yu,H.P.: Hemeoxygenase-1
upregulation is critical for sirtinol-mediated attenuation of lung injury after
trauma-hemorrhage in a rodent model. Anesth.Analg.108(6): 1855-61, 2009.
20. Fu-Chao Liu,Chang-Hui Liao ,Yao-Wen Chang, Jiin-Tarng Liou, Yuan-Ji Day*:
Hydroxyethyl starch interfere human blood ex vivo coagulation, platelet function
and sedimentation. Acta Anaesthesiol Taiwan 47(2):71-8, 2009.
21. Yao-Wen Chang, Chang-Hui Liao, Yuan-Ji Day*: Platelet Function Analyzer
(PFA-100®) obtains higher sensitivity and specificity than Thromboelastography
(TEG®) in Detection of Platelet Dysfunction. Acta Anaesthesiol Taiwan
47(3):110-7, 2009.
22. Po-Liang Chen, Yung-Chih Hsiang, Yao-Wen Chang, Chun-Yu Chen, Yuan-Ji
Day*: Novel Variants near the Central Domain of RYR1 in Two Malignant
Hyperthermia Susceptible Families from Taiwan. Anesth.Analg.109(4):1273-77,
2009.
23. Liu,F.C.; Liao,C.H.; Chang,Y.W.; Liou,J.T.; Day,Y.J.*: A new insight of
anti-platelet effects of sirtinol in platelets aggregation via cyclic AMP
phosphodiesterase. Biochem.Pharmacol. 77(8): 1364-73, 2009.
24. Day,Y.J.*: Will the platelets be the novel target of peri-operative inflammation?
Acta Anaesthesiol Taiwan 47(2):53-5, 2009.
25. Huang,J.P.; Huang,S.S.; Deng,J.Y.; Chang,C.C.; Day,Y.J.; Hung,L.M. Insulin and
resveratrol act synergistically, preventing cardiac dysfunction in diabetes, but the
advantage of resveratrol in diabetics with acute heart attack is antagonized by
insulin. Free Radic.Biol.Med.49(11):1710-1721, 2010
26. Hsieh,Y.H.; Huang,S.S.; Day,Y.J.; Wei,F.C.; Hung,L.M. Involvement of YC-1 in
extracellular signal-regulated kinase action in rat cremasteric muscle.
J.Pharm.Pharmacol.62(12):1746-1752, 2010
27. Liao,C.H.;
Chen,J.J.;
Lin,J.E.;
Liu,C.H.;
Tseng,C.P.;
Day,Y.J.
5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,7-dimethoxy-4H-chromen-4-one
(MSF-2) suppresses fMLP-mediated respiratory burst in human neutrophils by
inhib-iting phosphatidylinositol 3-kinase activity. J.Cell Physiol.(online, in press),
2010
28. Liu,F.C.; Liou,J.T.; Li,A.H.; Day,Y.J.; Yu,H.P. The effect of warmed ropivacaine
to body temperature on epidural sensory block characteristics.
J.Clin.Anesth.22(2): 110-114, 2010
29. Liou,J.T.; Lui,P.W.; Liu,F.C.; Lai,Y.S.; Day,Y.J*. Exogenous granulocyte
colony-stimulating factor exacerbate pain-related behaviors after peripheral nerve
injury. J Neuroimmunol. 232(1-2):83-93, 2011
Jiin-Tarng Liou ;Fu-Chao Liu; Chih-Chieh Mao; Ying-Shu Lai; Y.J. Day*;
Inflammation Confers Dual Effects on Nociceptive Processing in a Chronic
Neuropathic Pain Model. Anesthesiology 114(3):660-672, 2011