CURRICULUM VITAE NAME: Toshiro Matsui SEX: Male Institute: Department of Bioscience and Bioenvironmental Sciences, Faculty of Agriculture, Graduate School of Kyushu University, 6-10-1, Hakozaki, Higashi-ku, Fukuoka 812-8581, Japan Tel (0081)-92-642-3012 Fax (0081)-92-642-3012 E-mail; tmatsui@agr.kyushu-u.ac.jp BIRTH DATE: August 4, 1962 MARITAL STATUS: Married EDUCATION: B.A., Agricultural Chemistry, Kyushu University, Fukuoka, Japan March 1986 Ph.D. (D. Agric.), Agricultural Chemistry, Kyushu University, Fukuoka, Japan, March 1991 EMPLOYMENT: 1991-2000 Assistant Professor Laboratory of Food Analysis, Department of Food Science and Technology, Faculty of Agriculture, Kyushu University 2000-up to date Associate Professor Laboratory of Food Analysis, Department of Bioscience and Bioenvironmental Sciences, Faculty of Agriculture, Graduate School of Kyushu University, FIELD: My current special field is the" study on the elucidation of food components exerting a physiologically functional property.” Namely, prophylaxis of hypertension and diabetic diseases by bioactive food components, and clarification of their modulating mechanism in vivo. 1 The list of papers: Original papers and reviews (2006-) (1) Toshiro Matsui, Isiaka Ogunwande, Kanthi J. M. Abesundara, and Kiyoshi Matsumoto: Anti-hyperglycemic Potential of Natural Products. Mini-Reviews in Medicinal Chemistry, 6(3), 109-120 (2006). (2) Mitsuru Tanaka, Toshiro Matsui, Yusuke Ushida and Kiyoshi Matsumoto: Vasodilating action of di-peptides in thoracic aortas from spontaneously hypertensive rats. Biosci. Biotechnol. Biochem., 70(9), 2292-2295 (2006). (3) Toshiro Matsui, Xiao Lin Zhu, Keisuke Watanabe, Keisuke Tanaka, Yoko Kusano, Kiyoshi Matsumoto: Combined administration of captopril with an antihypertensive Val-Tyr di-peptide to spontaneously hypertensive rats attenuates the blood pressure lowering effect. Life Sciences, 79(26), 2492-2498 (2006). (4) Xiao Lin Zhu, Keisuke Tanaka, Toshiro Matsui, Kiyoshi Matsumoto: Antihypertensive effect of captopril is greatly attenuated by combined administration of with antihypertensive peptide. J. Hypertension, 24(suppl.6), S204 (2006). (5) Yusuke Ushida, Toshiro Matsui, Kiyoshi Matsumoto, Hirokazu Hosoyama, Atsuhiro Mitomi, Yuko Sagesaka, Takami Kakuda: Endothelium-dependent vasolidating effect of buckwheat extract on rat aortas. J. Hypertension, 24(suppl.6), S319 (2006). (6) Mitsuru Tanaka, Mai Tokuyasu, Toshiro Matsui, Kiyoshi Matsumoto: A screening of bioactive peptide possessing vasodilating action. J. Hypertension, 24(suppl.6), S407 (2006). (7) Toshiro Matsui, Takashi Tanaka, Satomi Tamura, Asami Toshima, Kei Tamaya, Yuji Miyata, Kazunari Tanaka, and Kiyoshi Matsumoto: -Glucosidase Inhibitory Profile of Catechins and Theaflavins. J. Agric. Food Chem., 55(1), 99-105 (2007). (8) Isiaka Ajani Ogunwande, Toshiro Matsui, Tomoko Fujise and Kiyoshi Matsumoto: -Glucosidase Inhibitory Profile of Nigerian Medicinal Plants in Immobilized Assay System. Food Sci. Technol. Res., 13(2), 169-172 (2007). (9) Xiao-Lin Zhu, Toshiro Matsui, Keisuke Watanabe, Koso Shiraishi, Tatsuro Ueki, Kiyoshi Matsumoto: Simultaneous determination of angiotensin I-converting enzyme inhibitory peptides in tryptic casein hydrolysate by high-performance liquid chromatography combined with a replicate heart-cut column-switching technique. J. Agric. Food Chem., 55(21), 8367-8374 (2007). 2 (10) Xiao-Lin Zhu, Keisuke Watanabe, Koso Shiraishi, Tatsuro Ueki, Yoshiharu Noda, Toshiro Matsui, Kiyoshi Matsumoto: Identification of ACE-inhibitory peptides in salt-free soy sauce that are transportable across caco-2 cell monolayers. Peptides, 29(3), 338-344 (2008). (11) Mitsuru Tanaka, Mai Tokuyasu, Toshiro Matsui, Kiyoshi Matsumoto: Endothelium-independent vasodilation effect of di- and tri-peptides in thoracic aorta of Sprague-Dawley rats. Life Sci. 82(15-16), 869-875 (2008). (12) Isiaka A. Ogunwande, T. Matsui, K. Matsumoto, M. Shimoda and D. Kubmarawa: Constituent of the essential oil from the leaves of Acacia Tortilis (Forsk.) hayne. J. Essential Oil Research., 20(2), 116-119 (2008). (13) Yusuke Ushida, Toshiro Matsui, Mitsuru Tanaka, Kiyoshi Matsumoto, Hirokazu Hosoyama, Atsuhiro Mitomi, Yuko Sagesaka, Takami Kakuda: Endothelium-dependent vasorelaxation effect of rutin-free tartary buckwheat extract in isolated rat thoracic aorta. J. Nutr. Biochem., 19(10), 700-707 (2008). (14) Lieselot Vercruysse, Guy Smagghe, Toshiro Matsui, John Van Camp: Purification and Identification of an Angiotensin I-converting Enzyme (ACE) Inhibitory Peptide from the Gastrointestinal Hydrolysate of the Cotton Leafworm, Spodoptera Littoralis. Process Biochem., 43, 900-904 (2008). (15) Mitsuru Tanaka, Shinpei Watanabe, Mai Tokuyasu, Toshiro Matsui, Kiyoshi Matsumoto: Structure-activity relationship between vasodilating di- and tri-peptides in thoracic aorta of Sprague-Dawley rats. J. Hypertension, 26(suppl.1), S171 (2008). (16) Tomoko Fujise, Norihiko Terahara, Keiichi Fukui, Koichi Sugita, Hideaki Ohta, Toshiro Matsui, Kiyoshi Matsumoto: Durable antihyperglycemic effect of 6-O-caffeoylsophorose with -glucosidase inhibitory activity in rats. Food Sci. Technol. Res., 14(5), 477-484 (2008). (17) Masahiro Yoshiki, Keisuke Tsuge, Yumi Tsuruta, Takashi Yoshimura, Kazuyoshi Koganemaru, Toshihisa Sumi, Toshiro Matsui, Kiyoshi Matsumoto: Production of a new antioxidant compound from mycosporine-like amino acid, Porphyra-334, by heat treatment. Food Chem., 113, 1127-1132 (2009). (18) Toshiro Matsui, Mayu Shimada, Nozomi Saitoh and Kiyoshi Matsumoto: -Glucosidase inhibition assay in an enzyme-immobilized amino-microplate. Anal.Sci. 25(4), 559-562 (2009). (19) Mitsuru Tanaka, Shimpei Watanabe, Zhengquan Wang, Kiyoshi Matsumoto and 3 Toshiro Matsui: His-Arg-Trp potently attenuates contracted tension of thoracic aorta of Sprague-Dawley rats through the suppression of extracellular Ca2+ influx. Peptides, 30, 1502-1507 (2009). (20) Takashi Tanaka, Yuji Miyata, Kei Tamaya, Rie Kusano, Yusuke Matsuo, Shizuka Tamaru, Kazunari Tanaka, Toshiro Matsui, Masamichi Maeda, Isao Kouno: Increase of theaflavin gallates and thearubigins by acceleration of catechin oxidation in a new fermented tea product obtained by tea-rolling processing of loquat (Eriobotrya japonica) and green tea leaves. J. Agric. Food Chem., 57(13), 5816-5822 (2009). (21) Toshiro Matsui, Masao Sato, Mitsuru Tanaka, Yasuna Yamada, Shimpei Watanabe, Yumiko Fujimoto, Katsumi Imaizumi, Kiyoshi Matsumoto: Vasodilating di-peptide Trp-His can prevent atherosclerosis in apolipoprotein E-deficient mice. Br. J. Nutr., in press. (22) Toshiro Matsui, Sachiko Korematsu, Eui-Baek Byun, Taichi Nishizuka, Shunji Ohshima and Tomomasa Kanda: Apple Procyanidins Induce Vascular Relaxation in Isolated Rat Aorta through NO/cGMP Pathway in Combination with Hyperpolarization by Multiple K+ Channel Activations. Biosci. Biotechnol. Biochem., 73(10), 2246-2251 (2009). (23) Norihiko Terahara, Toshiro Matsui,Kanako Minoda, Kanae Nasu, Risa Kikuchi, Keiichi Fukui, Hiroshi Ono, and Kiyoshi Matsumoto: Functional new acylated sohoroses and deglucosylated anthocyanins in a fermented red vinegar. J. Agric. Food Chem., 57(18), 8331-8338 (2009). (24) Takashi Hasegawa, Toshiro Matsui, and Kiyoshi Matsumoto: Application of confocal laser scanning microscope technique to visualize dynamic sorption behavior of perylene in cellulose acetate film. J. Appl. Polym. Sci., in press (25) Takashi Hasegawa, Toshiro Matsui, and Kiyoshi Matsumoto: Comparative study of additives on visualized dynamic sorption behavior of perylene in cellucose acetate film by confocal laser scanning microscope technique. J. Appl. Polym. Sci., in press. (26) Kei Tamaya, Toshiro Matsui, Asami Toshima, Mai Noguchi, Qui Jui, Yuji Miyata, Takashi Tanaka and Kazunari Tanaka: Suppression of blood glucose level by a new fermented tea obtained by tea-rolling processing of loquat (Eriobotrya japonica) and green tea leaves in disaccharides-loaded Sprague-Dawley rats. J Sci. Food Agr., in press. 4 Recent books: 1) Toshiro Matsui and Mitsuru Tanaka: Anti-hypertensive peptides and their underlying mechanisms (chapter 2) In Biologically Active Food Proteins and Peptides in HealthFundamental and Clinical aspects- (Eds.) Mine, Y., Li-Chan, E.C.Y., Jiang, B., IFT Book Series, Wiley Blackwell (Iowa), 2009. 2) Toshiro Matsui and Norihiko Terahara: Structure-Bioactivity Relations of Acylated Anthocyanins and their Related Polyphenols In Annual Reviews in Phytomedicine (Eds.) Mahmud Tareq Hassan Khan., Bentham Science Publisher, The Netherlands, 2009. 3) Norihiko Terahara and Toshiro Matsui: Stability and Functionality of acylated anthocyanins, ed. by Tetsuya Konishi and Takashi Ichiyanagi in “Anthocyanins as food factor: Recent Progress in Studies on Bioavailability and Health Promotion Effects, 2008”, Research Signpost, India 2008. 4) Norihiko Terahara and Toshiro Matsui: Structures and functionalities of acylated anthocyanins. 232nd ACS Symposium Series, San Francisco, USA, 2006. 5) T T.Matsui, and K.Matsumoto, in " Antihypertensive Peptides from Natural Resources (Chapter 15)", ed. by M.T.H.Khan and A.Ather, "Lead Molecules from Natural Products: Discovery and Trends". Elsevier B.V., The Netherlands, pp.259-276 (2006). 5